To unlearn the meaning of a sustainable water resource conservation is now an essential issue in using of sustained, sound, and high-quality water in the world. In this paper, a water quality purification by the Schum...To unlearn the meaning of a sustainable water resource conservation is now an essential issue in using of sustained, sound, and high-quality water in the world. In this paper, a water quality purification by the Schumann frequencies was first considered through the murmuring sound of upper reach at the mountain stream (Kyoto Pref., Japan) regarding the conservation of water resources. Second, water is changing freely and easily accepting the wavelength of all the sounds. We therefore referred to a flow and dynamic equilibrium to realize and understand the water quality purification process. Finally, a “consciousness only Buddhist philosophy” of water quality as an analogical approach was introduced to realize and understand the water purification process. As a result, we have confirmed the water purification capability by Schmann frequencies in an experiment on water quality. And through the experiment, we have realized the importance/significance to find the meaning for a person’s primary meaningless such as 1) meaning connection among life, environment, and economics as a condition of human life, 2) energy, entropy and fluctuation under law of thermodynamics, 3) a metaphor between water quality and mutual possession of the ten worlds based on conscious-only theory, and 4) sense of wonder through the water purification process.展开更多
In Xujiadai,a small village in east China,baseball,a niche sport in the country,has become an engine for rural growth.To date,the village,located in Jiaxing City,Zhejiang Province,has hosted over ioo baseball and soft...In Xujiadai,a small village in east China,baseball,a niche sport in the country,has become an engine for rural growth.To date,the village,located in Jiaxing City,Zhejiang Province,has hosted over ioo baseball and softball tournaments,earning it the title of China's No.I Baseball Village.A decade ago,most villagers in Xujiadai were engaged in pig farming.In recent years,as China advanced nationwide rural environmental improvement efforts,the village also undertook cleanup initiatives.展开更多
In the countryside of east Zhejiang Province,a quiet village has hit a home run.Xujiadai,once a place known for pig farming and environmental pollution,is drawing visitors from across China with a sport still uncommon...In the countryside of east Zhejiang Province,a quiet village has hit a home run.Xujiadai,once a place known for pig farming and environmental pollution,is drawing visitors from across China with a sport still uncommon in the country:baseball.展开更多
Human cardiac organoids have revolutionized the study of cardiac development,disease modeling, drug discovery, and regenerative therapies. This review systematically discusses strategies and progress in the constructi...Human cardiac organoids have revolutionized the study of cardiac development,disease modeling, drug discovery, and regenerative therapies. This review systematically discusses strategies and progress in the construction of cardiac organoids, categorizing them into three main types:cardiac spheroids, self-organizing/assembloid organoids, and organoid-on-a-chip systems. This review uniquely integrates the advances in vascularization, organ-on-chip design, and environmental cardiotoxicity modeling within cardiac organoid platforms, offering a critical synthesis that is absent in the literature. In the context of escalating environmental threats to cardiovascular health, there is an urgent need for physiologically relevant models to accurately identify cardiac toxicants and elucidate their underlying mechanisms of action. This review highlights advances in cardiac organoid applications for disease modeling-including congenital heart defects and acquired cardiovascular diseases-drug development, toxicity screening, and the study of environmentally induced cardiovascular pathogenesis. In addition, it critically examines ongoing challenges and underscores opportunities brought by bioengineering approaches. Finally, we propose future directions for developing standardized cardiac organoid platforms with clinical predictability, aiming to expand the utility of this technology across broader research applications.展开更多
As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to ...As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to 21 July 2025.This trip to Gansu Province was organised under the China-Africa Joint Centre for Agricultural Demonstration and Training in Arid Regions programme,an initiative aligned with President Xi Jinping’s call for deeper China-Africa cooperation.展开更多
Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general contr...Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general control zones—are established based on the ecological red line,the lower-limit line for environmental quality,and the resource use line.Human activities are regulated through a permit system.Integrated and multifactorial protection of soil,plant,hydrological,and atmospheric elements is promoted at the regional level.A follow-up assessment contributes to the improvement of policy implementation and effectiveness.This study demonstrates the achievements of the TLOP policy in Sichuan Province.Results show that(1)276 protection zones have been established under the ecological red line,covering key ecosystems and protected areas to ensure environmental security.Under the lower-limit line,1,626 functional(priority,key,and general control)zones have been designated to regulate air,water,and soil quality,enhancing environmental capacity and pollution control.(2)Through the integration and merging of the three lines,1,128 integrated management zones have been established,including 375,625,and 128 priority protection,critical control,and general control zones,respectively.Each zone has its own list of environmental permits to regulate human activities according to different environmental protection and natural resource development regimes.(3)The design of the follow-up assessment index system was informed by regional primary functions and industrial structure.The index system for provinces and cities is structured around three primary indicators—implementation updating,application,and guarantees—and 15 secondary indicators.The system for critical control zones is structured around environmental access,management,and effectiveness and 14 secondary indicators.A stringent environmental zoning system has been established through the TLOP policy,thereby safeguarding environmental security,promoting harmonious existence between humans and nature,and supporting the vision of Beautiful China.展开更多
A novel layered cobalt–magnesium double hydroxide composite(L-CMs)was successfully prepared using a simple onestep co-precipitation method.Static adsorption experiments were conducted to examine the removal efficacy ...A novel layered cobalt–magnesium double hydroxide composite(L-CMs)was successfully prepared using a simple onestep co-precipitation method.Static adsorption experiments were conducted to examine the removal efficacy of U(Ⅵ)from aqueous solutions by the L-CMs and analyze the removal mechanism.L-CMs efficiently removed U(Ⅵ)from the aqueous solution under an adsorption time of 60 min,dosage of 0.4 g/L,and pH of 5.5 at room temperature,and the removal efficiency of U(Ⅵ)reached 94.59%with an initial U(Ⅵ)concentration of 10 mg/L.The adsorption process was fitted to the pseudosecond-order kinetic and Langmuir models,indicating that monolayer chemical adsorption occurred primarily.The maximum adsorption capacity fitted using the Langmuir model was 105.49 mg/g.Thermodynamic analysis revealed that U(Ⅵ)adsorption by L-CMs was endothermic.Structural characterization results showed that the primary mechanism involved the complexation of U(Ⅵ)by–OH,CO_(3)^(2-)and ion exchange by Mg^(2+)and the presence of layered Co(OH)_(2) in the L-CMs,which potentially facilitated ion exchange.The preparation of the composite materials was simple,and the synergistic effect between the materials enhanced the ion exchange of Mg^(2+)in the materials and enriched the content of functional groups,making it a potential candidate for the treatment of uranium-containing wastewater.展开更多
Poor solubility often results in low efficacy of antitumor drugs.Nevertheless,limited research has been conducted on the potential decrease in drug efficacy following the self-assembly of hydrophobic pure drugs into n...Poor solubility often results in low efficacy of antitumor drugs.Nevertheless,limited research has been conducted on the potential decrease in drug efficacy following the self-assembly of hydrophobic pure drugs into nanodrugs,and solutions to this problem are even rarer.Loading water-insoluble antitumor drugs into nanocarriers offers a promising solution.However,intricate carrier preparation,limited drug loading capacity,and carrier-associated safety remain key challenges.In this study,based on the discovery that hydrophobic gambogic acid(GA) self-assembles into nanostructures with diminished antitumor efficacy in aqueous environments,we developed a carrier-free nanodrug system,designated as GA-S-S-AS nanoparticles(NPs),characterized by straightforward preparation,high drug loading,fluorescence imaging,tumor-targeting,and responsive drug release in reducing environments.Specifically,the hydrophobic GA was covalently linked to the hydrophilic aptamer through a disulfide bond and then self-assembled into the nanodrugs.About 92 % of drug was encapsulated in self-assembled NPs,demonstrating remarkable stability under physiological conditions and controlled release of GA in the high-glutathione environment characteristic of tumor sites.Furthermore,by utilizing the synergistic interaction between the enhanced permeability and retention(EPR) effect and ligand-receptor active targeting mechanisms,the nanodrugs significantly increased the accumulation of GA at tumor locations.Consequently,the nanodrugs exhibited optimal therapeutic efficacy against the tumor both in vitro and in vivo,significantly inhibiting tumor growth.Furthermore,the nanodrugs demonstrated enhanced biosafety compared to free GA,effectively reducing GA-induced hepatotoxicity.Taken together,these findings underscore the significant potential of this multifunctional carrier-free nanodrugs for the targeted delivery of GA,thereby laying a foundation for future endeavors aimed at developing novel formulations of hydrophobic antitumor drugs.展开更多
Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantati...Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantation process including preoperative evaluation,donation,organ and patient transportation,surgery,postoperative recovery,and follow-up.This is a topic that has not been fully addressed yet,but its importance is being increasingly appreciated in surgery.The aim of this study was to investigate the carbon footprint associated with transplantation and propose sustainable mitigating solutions.A comprehensive review of the existing literature on transplantation was conducted and supplemented with findings from the broader fields of surgical and perioperative care,given the scarcity of available data.The analysis identified the most involved environmental factors and attempted to offer practical solutions based on current sustainability practices.Notably,no study has yet examined the carbon footprint associated with the entire transplantation procedure.Only five studies have attempted to assess the environmental impact of kidney or liver transplants,but they focused,almost explicitly,on specific steps of the process.By employing an extrapolative methodology from the broader surgical field,we determined that the primary contributors to the environmental impact of transplantation are energy,consumables and materials,anesthesia and pharmaceuticals,transportation,and water.This review offers practical solutions utilizing the 5R framework,emphasizing sustainability to ensure transplantation remains clinically and environmentally relevant.展开更多
Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems....Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems.However,biogeographical research on the biomass of forest bryophytes is inadequately studied and has been limited to elevational gradients.We conducted a systematic cross-regional survey of bryophyte biomass across 413 forest sites in Sichuan Province,China.We analyzed how each environmental variable,including climatic and atmospheric factors,overstory covers,and soil nutrients,relates to bryophyte biomass and quantified their relative contributions.The results indicate that,largely similar to previous local investigations and experiments,at a large scale,bryophytes are abundant in forests with lower temperature,nitrogen deposition,vapor pressure deficit,and tree and herb covers,as well as higher light availability.Moreover,bryophyte biomass is positively associated with soil carbon and nitrogen content.These environmental variables are closely related and jointly influence bryophyte biomass,with mean annual temperature being the most significant factor(accounting for 83%of the relative contribution).The biogeographical patterns of bryophyte biomass contribute to deepening our understanding of their adaptations to multiple environmental variables and enable us to predict their responses to global climate change.These patterns also provide essential evidence for establishing more accurate terrestrial vegetation ecosystem models.展开更多
Environment serves as the pivotal medium to produce fermented food,with fluctuations in environmental factors exerting a profound impact on the modulation of fermentation microbial communities.Such shifts are crucial ...Environment serves as the pivotal medium to produce fermented food,with fluctuations in environmental factors exerting a profound impact on the modulation of fermentation microbial communities.Such shifts are crucial for the distinctiveness of fermented food flavor and the variability in quality.Chinese liquor(Baijiu)is one of the typical representatives of spontaneous fermented food.In this review,the multifaceted relationship between regional environmental attributes and the fermentation dynamics of Baijiu was examined,with a spotlight on the strong-flavor,sauce-flavor,and light-flavor varieties.It reveals the influence of regional environmental factors and brewing environmental factors on microbial function and metabolism,which results in the formation of unique flavor characteristics of Baijiu.The 9 main factors affecting the microecology of Baijiu fermentation were further explored,including environmental sensitivity,microbial interactions,biogeographic patterns,and key abiotic factors such as temperature and humidity.Environmental factor management is crucial for controlling microbial community in fermentation.Intelligent detection of the fermentation system is combined with artificial intelligence to realize the digitalization of Baijiu fermentation,with a view to further studying the environmental mechanism or quantitative control relationship of natural fermentation,improving the environmental stability of natural fermentation,and promoting the mechanization and intelligence of fermentation production.展开更多
Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications i...Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.展开更多
Ascorbate(Asc),commonly known as vitamin C,is a vital molecule for plant growth,development,and stress resilience.It is also known to play a crucial role in various physiological processes,including photosynthesis,cel...Ascorbate(Asc),commonly known as vitamin C,is a vital molecule for plant growth,development,and stress resilience.It is also known to play a crucial role in various physiological processes,including photosynthesis,cell division,and differentiation.This article thoroughly explores the processes governing the metabolism of Asc in plants and its roles in physiological functions.It lays down a robust theoretical groundwork for delving into Asc production,transportation,functions,and its potential applications in stress alleviation and horticulture.Furthermore,recent studies indicate that Asc plays a role in regulating fruit development and affecting postharvest storage characteristics,thereby influencing fruit ripening and resilience to stress.Hence,there is a growing importance in studying the synthesis and utilization of Asc in plants.Although the critical role of Asc in controlling plant redox signals has been extensively studied,the precise mechanisms by which it manages cellular redox homeostasis to maintain the equilibrium between reactive oxygen scavenging and cell redox signaling remain elusive.This gap in knowledge presents fresh opportunities to explore how the production of Asc in plants is regulated and how plants react to environmental stressors.Furthermore,this article delves into the potential for a comprehensive investigation into the essential function of Asc in fruits,the development of Asc-rich fruits,and the enhancement of postharvest storage properties.展开更多
On January 23,during the 2026 CEFCO,the China Council for the Promotion of International Trade(CCPIT)released the Annual Report on China's Exhibition Industry.Wu Shengrong,Director-General of the CCPIT Exhibition ...On January 23,during the 2026 CEFCO,the China Council for the Promotion of International Trade(CCPIT)released the Annual Report on China's Exhibition Industry.Wu Shengrong,Director-General of the CCPIT Exhibition Management Department,stated that in 2025,the environment for China's exhibition industry continued to improve.展开更多
Epimedium is commonly used to treat bone injury and kidney disease,with prenylated flavonol glycosides(PFGs)as its active ingredients.It has attracted much attention due to prominent healthcare and therapeutic effects...Epimedium is commonly used to treat bone injury and kidney disease,with prenylated flavonol glycosides(PFGs)as its active ingredients.It has attracted much attention due to prominent healthcare and therapeutic effects,but faces problems of adulteration with closely related species and confusion about geographical origins.In this study,multiple technical approaches were employed to identify its genetic characteristics and metabolic differences.Based on DNA barcoding,20 batches of samples were analyzed.The genetic distances of matK,ITS and psbA-trnH within species were all smaller than those between species,and psbA-trnH along with ITS+psbA-trnH proved most effective in distinguishing botanical sources.With Inter-simple sequence repeat(ISSR)technology,12 highly polymorphic and reproducible primers were selected from 21,and 189 alleles were detected.Epimedium sagittatum showed distinct genetic diversity.Samples with similar genetic distance and geographical location also tended to cluster together.Eight index components were analyzed,and their contents showed significant differences.The total content ranged from 0.50%to 7.09%,and icariin and epimedin C were identified as potential biomarkers.Integrative analysis revealed that the differences in index components were jointly driven by genetic diversity and ecological factors.Additionally,“mean temperature of driest quarter”,“precipitation seasonality”,and“temperature annual range”were identified as key environmental factors.This study provides a reliable experimental basis for the authenticity and quality evaluation of Epimedium.展开更多
A visible-light induced cascade sulfonation/cyclization reaction of 3-allyl-2-arylquinazolinones employing water as an environmentally friendly solvent was revealed.This transition metal-free protocol,using 9-mesityl-...A visible-light induced cascade sulfonation/cyclization reaction of 3-allyl-2-arylquinazolinones employing water as an environmentally friendly solvent was revealed.This transition metal-free protocol,using 9-mesityl-10-methylacridinium perchlorate as the photocatalyst,represents a masterly tactic for the synthesis of sulfonated dihydroisoquinolino[1,2-b]quinazolinones featuring mild conditions,facile operation,and broad substrate scope.展开更多
Non-structural carbohydrates(NSCs)are critical for plant drought adaptation,but their environmental drivers under prolonged drought remains unclear.We investigated seasonal NSCs dynamics in the leaf,stem and root of P...Non-structural carbohydrates(NSCs)are critical for plant drought adaptation,but their environmental drivers under prolonged drought remains unclear.We investigated seasonal NSCs dynamics in the leaf,stem and root of Picea crass ifolia(Qinghai spruce)during the growing seasons of2021-2023 under intensifying drought at three altitudes in Qilian Mountains,Northwest China.Our results revealed synchronous seasonal patterns in soluble sugar,starch,and total non-structural carbohydrate within the same year,contrasting with marked altitudinal disparities.As drought progressed(from 2021 to 2023),soluble sugars initially increased(2022)then declined(2023),while starch showed consistent reduction(except leaves).Moreover,the altitude of peak NSCs concentrations shifted from 3200 m in 2021to 2700 m in 2023.In particular,prolonged drought alters the environmental factors affecting NSCs.NSCs demonstrated significant positive correlations with soil temperature during humid 2021,then negatively with air temperature,vapor pressure deficit,and precipitation during 2022's initial drought,whereas under 2023's persistent drought conditions,soil temperature and water content emerged as dominant drivers.Concurrently,the ratio of soluble sugar to starch transitioned from air temperature and precipitation associations(2021-2022)to soil parameter dependence in2023.These findings provide new insights into the seasonal carbon dynamics of Qinghai spruce and the environmental response mechanisms under increasing drought stress,contributing to a better understanding of tree physiological adaptations in drought stress.展开更多
Starting from the foundational static traits underlying the growth and development of flue-cured tobacco, this research conducts a systematic examination of the phenomena and theoretical principles associated with env...Starting from the foundational static traits underlying the growth and development of flue-cured tobacco, this research conducts a systematic examination of the phenomena and theoretical principles associated with environment-driven adaptive changes during its cultivation. It was found that environmental variables-including temperature, light, and moisture-elicit directional shifts in static traits ( e.g. , chemical composition, morphological architecture, and leaf tissue structure) toward enhanced environmental adaptation, characterized by graduality, juvenility, similarity, and correlativity. Upon alterations in ambient conditions, flue-cured tobacco modulates its static traits through integrated physical, chemical, and biological-genetic mechanisms, aiming to optimize resource utilization, mitigate environmental constraints, and preserve internal homeostasis alongside metabolic balance. The investigation further reveals that the adaptive scope of flue-cured tobacco to field environments is malleable and can be extended and elevated via adaptive conditioning commencing at the juvenile stage. In addition, the adaptive alignment between static traits and environmental parameters exerts a substantial impact on the plant s growth dynamics, yield performance, and quality attributes. Beyond its relevance to flue-cured tobacco, the proposed theory offers a meaningful framework for elucidating the pervasive adaptive strategies employed by plants and broader biological systems in response to environmental contingencies.展开更多
The surge in environmental pollution in recent years driven by numerous pollutants has necessitated the search for efficient removal methods.Phytoremediation is an eco-friendly technique that provides multiple benefit...The surge in environmental pollution in recent years driven by numerous pollutants has necessitated the search for efficient removal methods.Phytoremediation is an eco-friendly technique that provides multiple benefits over conventional methods of removing contaminants.Despite the numerous benefits of this technique,it has certain limitations that can be addressed by incorporating nanoparticles to improve its effectiveness.This review paper aims to explore the impact of heavy metal pollution on plants and human health.It highlights the role and mechanism of nanoparticles in enhancing phytoremediation,their application in the detection of heavy metals,and the strategies for the safe disposal of phytoremediation biomass.Biosynthesized nanoparticles are eco-friendly and non-toxic,with applications in biomedical and environmental fields.Nanoparticles can be used in the form of nano biosensors like smartphone-operated wireless sensors made from Cinnamomum camphora,enabling efficient detection of heavy metal ions.According to the studies,nanoparticles remove 80%–97%of heavy metals by various methods like reduction,precipitation,adsorption,etc.The phytoremediation biomass disposal can be done by heat treatment,phytomining,and microbial treatment with some modifications to further enhance their results.Phytoremediation is an environmentally friendly technique but requires further research and integration with biomass energy production to overcome scalability challenges and ensure safe biomass disposal.展开更多
Purpose: Normobaric hypoxia(NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless, the versa...Purpose: Normobaric hypoxia(NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless, the versatility of administration methods may influence the outcomes.Methods: Web of Science, Scopus, SPORTDiscus and Pub Med/MEDLINE were searched to identify studies assessing the effect of NH administered by face mask or chamber/tent equipment on maximal oxygen uptake( VO2max) after a training period. An overall meta-analysis and sub-analysis of total program session volume(low, moderate, high), participants' training level(trained, active, sedentary), and the severity of hypoxia(moderate, severe) were conducted to explore the effects of the NH-administration system.Results: Eighteen studies were included. Compared with normoxia, NH showed a moderate global improvement in VO2max(standardized mean difference [SMD] = 0.74;p = 0.06), favoring the chamber/tent(SMD = 1.30;p< 0.01) over the face mask. Sub-analysis showed a very large effect in support of the hypoxic chamber/tent among sedentary individuals and training programs with a high volume of sessions. Severe hypoxia did not yield conclusive findings in VO2max improvements, although the chamber/tent proved more effective(SMD = 1.42;p< 0.01) than the face mask under moderate hypoxia.Conclusions: Chambers/tents may slightly accentuate the benefit of NH on aerobic performance, particularly in participants with limited training experience following a high volume of sessions under moderate hypoxia.However, the variability of sub-analysis factors(session volume, participants' training level, and methodological approaches) between studies using each type of hypoxia-generating equipment may influence this result.展开更多
文摘To unlearn the meaning of a sustainable water resource conservation is now an essential issue in using of sustained, sound, and high-quality water in the world. In this paper, a water quality purification by the Schumann frequencies was first considered through the murmuring sound of upper reach at the mountain stream (Kyoto Pref., Japan) regarding the conservation of water resources. Second, water is changing freely and easily accepting the wavelength of all the sounds. We therefore referred to a flow and dynamic equilibrium to realize and understand the water quality purification process. Finally, a “consciousness only Buddhist philosophy” of water quality as an analogical approach was introduced to realize and understand the water purification process. As a result, we have confirmed the water purification capability by Schmann frequencies in an experiment on water quality. And through the experiment, we have realized the importance/significance to find the meaning for a person’s primary meaningless such as 1) meaning connection among life, environment, and economics as a condition of human life, 2) energy, entropy and fluctuation under law of thermodynamics, 3) a metaphor between water quality and mutual possession of the ten worlds based on conscious-only theory, and 4) sense of wonder through the water purification process.
文摘In Xujiadai,a small village in east China,baseball,a niche sport in the country,has become an engine for rural growth.To date,the village,located in Jiaxing City,Zhejiang Province,has hosted over ioo baseball and softball tournaments,earning it the title of China's No.I Baseball Village.A decade ago,most villagers in Xujiadai were engaged in pig farming.In recent years,as China advanced nationwide rural environmental improvement efforts,the village also undertook cleanup initiatives.
文摘In the countryside of east Zhejiang Province,a quiet village has hit a home run.Xujiadai,once a place known for pig farming and environmental pollution,is drawing visitors from across China with a sport still uncommon in the country:baseball.
基金supported by the Innovation Promotion Program of NHC and Shanghai Key Labs,SIBPT(grant number PT2025-01)。
文摘Human cardiac organoids have revolutionized the study of cardiac development,disease modeling, drug discovery, and regenerative therapies. This review systematically discusses strategies and progress in the construction of cardiac organoids, categorizing them into three main types:cardiac spheroids, self-organizing/assembloid organoids, and organoid-on-a-chip systems. This review uniquely integrates the advances in vascularization, organ-on-chip design, and environmental cardiotoxicity modeling within cardiac organoid platforms, offering a critical synthesis that is absent in the literature. In the context of escalating environmental threats to cardiovascular health, there is an urgent need for physiologically relevant models to accurately identify cardiac toxicants and elucidate their underlying mechanisms of action. This review highlights advances in cardiac organoid applications for disease modeling-including congenital heart defects and acquired cardiovascular diseases-drug development, toxicity screening, and the study of environmentally induced cardiovascular pathogenesis. In addition, it critically examines ongoing challenges and underscores opportunities brought by bioengineering approaches. Finally, we propose future directions for developing standardized cardiac organoid platforms with clinical predictability, aiming to expand the utility of this technology across broader research applications.
文摘As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to 21 July 2025.This trip to Gansu Province was organised under the China-Africa Joint Centre for Agricultural Demonstration and Training in Arid Regions programme,an initiative aligned with President Xi Jinping’s call for deeper China-Africa cooperation.
基金supported by the National Natural Science Foundation of China(grant numbers 42171085)and the National Key R&D Program of China(Grant No.2024YFF1307801,2024YFF1307804).
文摘Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general control zones—are established based on the ecological red line,the lower-limit line for environmental quality,and the resource use line.Human activities are regulated through a permit system.Integrated and multifactorial protection of soil,plant,hydrological,and atmospheric elements is promoted at the regional level.A follow-up assessment contributes to the improvement of policy implementation and effectiveness.This study demonstrates the achievements of the TLOP policy in Sichuan Province.Results show that(1)276 protection zones have been established under the ecological red line,covering key ecosystems and protected areas to ensure environmental security.Under the lower-limit line,1,626 functional(priority,key,and general control)zones have been designated to regulate air,water,and soil quality,enhancing environmental capacity and pollution control.(2)Through the integration and merging of the three lines,1,128 integrated management zones have been established,including 375,625,and 128 priority protection,critical control,and general control zones,respectively.Each zone has its own list of environmental permits to regulate human activities according to different environmental protection and natural resource development regimes.(3)The design of the follow-up assessment index system was informed by regional primary functions and industrial structure.The index system for provinces and cities is structured around three primary indicators—implementation updating,application,and guarantees—and 15 secondary indicators.The system for critical control zones is structured around environmental access,management,and effectiveness and 14 secondary indicators.A stringent environmental zoning system has been established through the TLOP policy,thereby safeguarding environmental security,promoting harmonious existence between humans and nature,and supporting the vision of Beautiful China.
基金financially supported by the National Natural Science Foundation of China(Nos.22266003,22006013,12005037)Academic and Technical Leaders of Major Disciplines in Jiangxi Province(20225BCJ23020)Graduate Science and Technology Innovation Project of Jiangxi Province(YC2023-S563)。
文摘A novel layered cobalt–magnesium double hydroxide composite(L-CMs)was successfully prepared using a simple onestep co-precipitation method.Static adsorption experiments were conducted to examine the removal efficacy of U(Ⅵ)from aqueous solutions by the L-CMs and analyze the removal mechanism.L-CMs efficiently removed U(Ⅵ)from the aqueous solution under an adsorption time of 60 min,dosage of 0.4 g/L,and pH of 5.5 at room temperature,and the removal efficiency of U(Ⅵ)reached 94.59%with an initial U(Ⅵ)concentration of 10 mg/L.The adsorption process was fitted to the pseudosecond-order kinetic and Langmuir models,indicating that monolayer chemical adsorption occurred primarily.The maximum adsorption capacity fitted using the Langmuir model was 105.49 mg/g.Thermodynamic analysis revealed that U(Ⅵ)adsorption by L-CMs was endothermic.Structural characterization results showed that the primary mechanism involved the complexation of U(Ⅵ)by–OH,CO_(3)^(2-)and ion exchange by Mg^(2+)and the presence of layered Co(OH)_(2) in the L-CMs,which potentially facilitated ion exchange.The preparation of the composite materials was simple,and the synergistic effect between the materials enhanced the ion exchange of Mg^(2+)in the materials and enriched the content of functional groups,making it a potential candidate for the treatment of uranium-containing wastewater.
基金the National Natural Science Foundation of China (Nos.21907076 and 31901908)the Natural Science Foundation of Tianjin (No.22JCQNJC01570)。
文摘Poor solubility often results in low efficacy of antitumor drugs.Nevertheless,limited research has been conducted on the potential decrease in drug efficacy following the self-assembly of hydrophobic pure drugs into nanodrugs,and solutions to this problem are even rarer.Loading water-insoluble antitumor drugs into nanocarriers offers a promising solution.However,intricate carrier preparation,limited drug loading capacity,and carrier-associated safety remain key challenges.In this study,based on the discovery that hydrophobic gambogic acid(GA) self-assembles into nanostructures with diminished antitumor efficacy in aqueous environments,we developed a carrier-free nanodrug system,designated as GA-S-S-AS nanoparticles(NPs),characterized by straightforward preparation,high drug loading,fluorescence imaging,tumor-targeting,and responsive drug release in reducing environments.Specifically,the hydrophobic GA was covalently linked to the hydrophilic aptamer through a disulfide bond and then self-assembled into the nanodrugs.About 92 % of drug was encapsulated in self-assembled NPs,demonstrating remarkable stability under physiological conditions and controlled release of GA in the high-glutathione environment characteristic of tumor sites.Furthermore,by utilizing the synergistic interaction between the enhanced permeability and retention(EPR) effect and ligand-receptor active targeting mechanisms,the nanodrugs significantly increased the accumulation of GA at tumor locations.Consequently,the nanodrugs exhibited optimal therapeutic efficacy against the tumor both in vitro and in vivo,significantly inhibiting tumor growth.Furthermore,the nanodrugs demonstrated enhanced biosafety compared to free GA,effectively reducing GA-induced hepatotoxicity.Taken together,these findings underscore the significant potential of this multifunctional carrier-free nanodrugs for the targeted delivery of GA,thereby laying a foundation for future endeavors aimed at developing novel formulations of hydrophobic antitumor drugs.
文摘Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantation process including preoperative evaluation,donation,organ and patient transportation,surgery,postoperative recovery,and follow-up.This is a topic that has not been fully addressed yet,but its importance is being increasingly appreciated in surgery.The aim of this study was to investigate the carbon footprint associated with transplantation and propose sustainable mitigating solutions.A comprehensive review of the existing literature on transplantation was conducted and supplemented with findings from the broader fields of surgical and perioperative care,given the scarcity of available data.The analysis identified the most involved environmental factors and attempted to offer practical solutions based on current sustainability practices.Notably,no study has yet examined the carbon footprint associated with the entire transplantation procedure.Only five studies have attempted to assess the environmental impact of kidney or liver transplants,but they focused,almost explicitly,on specific steps of the process.By employing an extrapolative methodology from the broader surgical field,we determined that the primary contributors to the environmental impact of transplantation are energy,consumables and materials,anesthesia and pharmaceuticals,transportation,and water.This review offers practical solutions utilizing the 5R framework,emphasizing sustainability to ensure transplantation remains clinically and environmentally relevant.
基金supported by the National Natural Science Foundation of China(No.31600316)the Sichuan Science and Technology Program(2023NSFSC0198)。
文摘Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems.However,biogeographical research on the biomass of forest bryophytes is inadequately studied and has been limited to elevational gradients.We conducted a systematic cross-regional survey of bryophyte biomass across 413 forest sites in Sichuan Province,China.We analyzed how each environmental variable,including climatic and atmospheric factors,overstory covers,and soil nutrients,relates to bryophyte biomass and quantified their relative contributions.The results indicate that,largely similar to previous local investigations and experiments,at a large scale,bryophytes are abundant in forests with lower temperature,nitrogen deposition,vapor pressure deficit,and tree and herb covers,as well as higher light availability.Moreover,bryophyte biomass is positively associated with soil carbon and nitrogen content.These environmental variables are closely related and jointly influence bryophyte biomass,with mean annual temperature being the most significant factor(accounting for 83%of the relative contribution).The biogeographical patterns of bryophyte biomass contribute to deepening our understanding of their adaptations to multiple environmental variables and enable us to predict their responses to global climate change.These patterns also provide essential evidence for establishing more accurate terrestrial vegetation ecosystem models.
基金financially supported by the National Natural Science Foundation of China(22138004)National Treasure Ecological Research Synergetic Innovation Center.
文摘Environment serves as the pivotal medium to produce fermented food,with fluctuations in environmental factors exerting a profound impact on the modulation of fermentation microbial communities.Such shifts are crucial for the distinctiveness of fermented food flavor and the variability in quality.Chinese liquor(Baijiu)is one of the typical representatives of spontaneous fermented food.In this review,the multifaceted relationship between regional environmental attributes and the fermentation dynamics of Baijiu was examined,with a spotlight on the strong-flavor,sauce-flavor,and light-flavor varieties.It reveals the influence of regional environmental factors and brewing environmental factors on microbial function and metabolism,which results in the formation of unique flavor characteristics of Baijiu.The 9 main factors affecting the microecology of Baijiu fermentation were further explored,including environmental sensitivity,microbial interactions,biogeographic patterns,and key abiotic factors such as temperature and humidity.Environmental factor management is crucial for controlling microbial community in fermentation.Intelligent detection of the fermentation system is combined with artificial intelligence to realize the digitalization of Baijiu fermentation,with a view to further studying the environmental mechanism or quantitative control relationship of natural fermentation,improving the environmental stability of natural fermentation,and promoting the mechanization and intelligence of fermentation production.
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-Level Talent Introduction Scientific Research Support Project.
文摘Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.
基金supported by the Lendület/Momentum Programme of the Hungarian Academy of Sciencesthe National Research, Development, and Innovation Office, Hungary (Grant Nos. LP2024/21 and K146791)+2 种基金Bayers fellowship program MEDHA and Department of Botany, University of Calicutthe financial assistance provided in the form of Junior Research Fellowship from the University Grants Commission (UGC), Indiathe financial assistance provided by the Council for Scientific and Industrial Research(CSIR), India
文摘Ascorbate(Asc),commonly known as vitamin C,is a vital molecule for plant growth,development,and stress resilience.It is also known to play a crucial role in various physiological processes,including photosynthesis,cell division,and differentiation.This article thoroughly explores the processes governing the metabolism of Asc in plants and its roles in physiological functions.It lays down a robust theoretical groundwork for delving into Asc production,transportation,functions,and its potential applications in stress alleviation and horticulture.Furthermore,recent studies indicate that Asc plays a role in regulating fruit development and affecting postharvest storage characteristics,thereby influencing fruit ripening and resilience to stress.Hence,there is a growing importance in studying the synthesis and utilization of Asc in plants.Although the critical role of Asc in controlling plant redox signals has been extensively studied,the precise mechanisms by which it manages cellular redox homeostasis to maintain the equilibrium between reactive oxygen scavenging and cell redox signaling remain elusive.This gap in knowledge presents fresh opportunities to explore how the production of Asc in plants is regulated and how plants react to environmental stressors.Furthermore,this article delves into the potential for a comprehensive investigation into the essential function of Asc in fruits,the development of Asc-rich fruits,and the enhancement of postharvest storage properties.
文摘On January 23,during the 2026 CEFCO,the China Council for the Promotion of International Trade(CCPIT)released the Annual Report on China's Exhibition Industry.Wu Shengrong,Director-General of the CCPIT Exhibition Management Department,stated that in 2025,the environment for China's exhibition industry continued to improve.
基金supported by Beijing Nova Program(20240484546)the Fundamental Research Funds for the Central Public Welfare Research Institutes(No.ZZ13-YQ-049,ZXKT22001)Shaanxi Province Key R&D Program Projects(2024SF-ZDCYL-03-10).
文摘Epimedium is commonly used to treat bone injury and kidney disease,with prenylated flavonol glycosides(PFGs)as its active ingredients.It has attracted much attention due to prominent healthcare and therapeutic effects,but faces problems of adulteration with closely related species and confusion about geographical origins.In this study,multiple technical approaches were employed to identify its genetic characteristics and metabolic differences.Based on DNA barcoding,20 batches of samples were analyzed.The genetic distances of matK,ITS and psbA-trnH within species were all smaller than those between species,and psbA-trnH along with ITS+psbA-trnH proved most effective in distinguishing botanical sources.With Inter-simple sequence repeat(ISSR)technology,12 highly polymorphic and reproducible primers were selected from 21,and 189 alleles were detected.Epimedium sagittatum showed distinct genetic diversity.Samples with similar genetic distance and geographical location also tended to cluster together.Eight index components were analyzed,and their contents showed significant differences.The total content ranged from 0.50%to 7.09%,and icariin and epimedin C were identified as potential biomarkers.Integrative analysis revealed that the differences in index components were jointly driven by genetic diversity and ecological factors.Additionally,“mean temperature of driest quarter”,“precipitation seasonality”,and“temperature annual range”were identified as key environmental factors.This study provides a reliable experimental basis for the authenticity and quality evaluation of Epimedium.
基金funds from Natural Science Foundation of Guangxi Province(Nos.2023GXNSFBA026304,2023GXNSFDA026063)the Guangxi Science and Technology Base and Special Talents(No.Guike AD20159047).
文摘A visible-light induced cascade sulfonation/cyclization reaction of 3-allyl-2-arylquinazolinones employing water as an environmentally friendly solvent was revealed.This transition metal-free protocol,using 9-mesityl-10-methylacridinium perchlorate as the photocatalyst,represents a masterly tactic for the synthesis of sulfonated dihydroisoquinolino[1,2-b]quinazolinones featuring mild conditions,facile operation,and broad substrate scope.
基金supported by the National Natural Science Foundation of China(No.42277481,42007410,32271667,42207537)。
文摘Non-structural carbohydrates(NSCs)are critical for plant drought adaptation,but their environmental drivers under prolonged drought remains unclear.We investigated seasonal NSCs dynamics in the leaf,stem and root of Picea crass ifolia(Qinghai spruce)during the growing seasons of2021-2023 under intensifying drought at three altitudes in Qilian Mountains,Northwest China.Our results revealed synchronous seasonal patterns in soluble sugar,starch,and total non-structural carbohydrate within the same year,contrasting with marked altitudinal disparities.As drought progressed(from 2021 to 2023),soluble sugars initially increased(2022)then declined(2023),while starch showed consistent reduction(except leaves).Moreover,the altitude of peak NSCs concentrations shifted from 3200 m in 2021to 2700 m in 2023.In particular,prolonged drought alters the environmental factors affecting NSCs.NSCs demonstrated significant positive correlations with soil temperature during humid 2021,then negatively with air temperature,vapor pressure deficit,and precipitation during 2022's initial drought,whereas under 2023's persistent drought conditions,soil temperature and water content emerged as dominant drivers.Concurrently,the ratio of soluble sugar to starch transitioned from air temperature and precipitation associations(2021-2022)to soil parameter dependence in2023.These findings provide new insights into the seasonal carbon dynamics of Qinghai spruce and the environmental response mechanisms under increasing drought stress,contributing to a better understanding of tree physiological adaptations in drought stress.
基金Supported by Changsha Tobacco Company Science and Technology Project(2020-2024A04).
文摘Starting from the foundational static traits underlying the growth and development of flue-cured tobacco, this research conducts a systematic examination of the phenomena and theoretical principles associated with environment-driven adaptive changes during its cultivation. It was found that environmental variables-including temperature, light, and moisture-elicit directional shifts in static traits ( e.g. , chemical composition, morphological architecture, and leaf tissue structure) toward enhanced environmental adaptation, characterized by graduality, juvenility, similarity, and correlativity. Upon alterations in ambient conditions, flue-cured tobacco modulates its static traits through integrated physical, chemical, and biological-genetic mechanisms, aiming to optimize resource utilization, mitigate environmental constraints, and preserve internal homeostasis alongside metabolic balance. The investigation further reveals that the adaptive scope of flue-cured tobacco to field environments is malleable and can be extended and elevated via adaptive conditioning commencing at the juvenile stage. In addition, the adaptive alignment between static traits and environmental parameters exerts a substantial impact on the plant s growth dynamics, yield performance, and quality attributes. Beyond its relevance to flue-cured tobacco, the proposed theory offers a meaningful framework for elucidating the pervasive adaptive strategies employed by plants and broader biological systems in response to environmental contingencies.
文摘The surge in environmental pollution in recent years driven by numerous pollutants has necessitated the search for efficient removal methods.Phytoremediation is an eco-friendly technique that provides multiple benefits over conventional methods of removing contaminants.Despite the numerous benefits of this technique,it has certain limitations that can be addressed by incorporating nanoparticles to improve its effectiveness.This review paper aims to explore the impact of heavy metal pollution on plants and human health.It highlights the role and mechanism of nanoparticles in enhancing phytoremediation,their application in the detection of heavy metals,and the strategies for the safe disposal of phytoremediation biomass.Biosynthesized nanoparticles are eco-friendly and non-toxic,with applications in biomedical and environmental fields.Nanoparticles can be used in the form of nano biosensors like smartphone-operated wireless sensors made from Cinnamomum camphora,enabling efficient detection of heavy metal ions.According to the studies,nanoparticles remove 80%–97%of heavy metals by various methods like reduction,precipitation,adsorption,etc.The phytoremediation biomass disposal can be done by heat treatment,phytomining,and microbial treatment with some modifications to further enhance their results.Phytoremediation is an environmentally friendly technique but requires further research and integration with biomass energy production to overcome scalability challenges and ensure safe biomass disposal.
基金supported by the Andalusian FEDER Operational Program [B-CTS-374-UGR20 and C-SEJ-015-UGR23]the Spanish Ministry of Science,Innovation and Universities [PGC2018-097388-BI00-MCI/AEI/FEDER,UE]。
文摘Purpose: Normobaric hypoxia(NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless, the versatility of administration methods may influence the outcomes.Methods: Web of Science, Scopus, SPORTDiscus and Pub Med/MEDLINE were searched to identify studies assessing the effect of NH administered by face mask or chamber/tent equipment on maximal oxygen uptake( VO2max) after a training period. An overall meta-analysis and sub-analysis of total program session volume(low, moderate, high), participants' training level(trained, active, sedentary), and the severity of hypoxia(moderate, severe) were conducted to explore the effects of the NH-administration system.Results: Eighteen studies were included. Compared with normoxia, NH showed a moderate global improvement in VO2max(standardized mean difference [SMD] = 0.74;p = 0.06), favoring the chamber/tent(SMD = 1.30;p< 0.01) over the face mask. Sub-analysis showed a very large effect in support of the hypoxic chamber/tent among sedentary individuals and training programs with a high volume of sessions. Severe hypoxia did not yield conclusive findings in VO2max improvements, although the chamber/tent proved more effective(SMD = 1.42;p< 0.01) than the face mask under moderate hypoxia.Conclusions: Chambers/tents may slightly accentuate the benefit of NH on aerobic performance, particularly in participants with limited training experience following a high volume of sessions under moderate hypoxia.However, the variability of sub-analysis factors(session volume, participants' training level, and methodological approaches) between studies using each type of hypoxia-generating equipment may influence this result.
