Objective:To study the correlation between CT dynamic enhanced scanning parameters and serum tumor markers before and after radiofrequency ablation in patients with lung cancer.Methods:60 patients with advanced non-sm...Objective:To study the correlation between CT dynamic enhanced scanning parameters and serum tumor markers before and after radiofrequency ablation in patients with lung cancer.Methods:60 patients with advanced non-small cell lung cancer who were treated in this hospital between January 2015 and January 2017 were divided into control group(n=30)and observation group(n=30)by random number table method.Control group received conventional intravenous chemotherapy,and observation group received intravenous chemotherapy combined with radiofrequency ablation.The differences in CT dynamic enhanced scanning parameter levels and serum tumor marker contents were compared between the two groups of patients before and after treatment.Pearson test was used to evaluate the correlation between CT dynamic enhanced scanning parameters and serum tumor marker contents in patients with advanced non-small cell lung cancer.Results:Before treatment,the differences in CT dynamic enhanced scanning parameter levels,non-organ-specific tumor marker contents and vascular tumor marker contents were not statistically significant between the two groups of patients(P>0.05).After treatment,CT dynamic enhanced scanning parameters PH and perfusion value levels of observation group were lower than those of control group(P<0.05);serum non-organ specific tumor markers CA125,CA153,CEA and CYFRA21-1 contents of observation group were lower than those of control group;serum vascular tumor markers VEGF,Ang-2,HIF-1 and MMP-9 contents were lower than those of control group(P<0.05).Pearson test showed that CT dynamic enhanced scanning parameters PH and perfusion value levels in patients with non-small cell lung cancer were positively correlated with serum non-organ specific tumor marker and vascular tumor marker contents.Conclusion:Adjuvant radiofrequency ablation can significantly reduce the tumor malignancy of patients with advanced non-small cell lung cancer.展开更多
Insulinomas are the most common category of pancreatic endocrine tumors,with an annual incidence of 1-4 cases per million people.Most are intrapancreatic,benign and solitary.Therefore,they have an excellent prognosis ...Insulinomas are the most common category of pancreatic endocrine tumors,with an annual incidence of 1-4 cases per million people.Most are intrapancreatic,benign and solitary.Therefore,they have an excellent prognosis after surgical resection.However,the localization diagnosis of insulinomas still poses a challenge to surgeons and radiologists.In this case,the tumor was occult and could not be found by either abdominal enhanced spiral computed tomography(CT)or ultrasonography.Therefore,we tried a new method of CT scanning and localized the tumor.展开更多
Aim:To explore the diagnostic value of spiral CT chest enhanced scan for adults with active pulmonary tuberculosis.Methods:The clinical data of 60 adult patients with active pulmonary tuberculosis who were treated in ...Aim:To explore the diagnostic value of spiral CT chest enhanced scan for adults with active pulmonary tuberculosis.Methods:The clinical data of 60 adult patients with active pulmonary tuberculosis who were treated in our hospital from January 2018 to November 2019 were retrospectively analyzed.All patients underwent conventional chest radiography and spiral CT chest enhanced scan.The number of tuberculosis diagnosis,the detection rate of special site lesions,and the detection rate of active pulmonary tuberculosis signs by the two methods were compared.Results:In 60 patients,the pathological results confirmed the existence of 75 tuberculosis lesions.The detection rate of spiral CT was 98.67%,which was not statistically significant compared with the detection rate of 92.00%(P>0.05)in the conventional chest X-ray.The detection rate of spiral CT enhanced scans for tuberculosis lesions in special sites was 100.00%,which was significantly higher than that of conventional chest X-ray of 7.69%,and the accuracy rate of active pulmonary tuberculosis signs was 98.85%higher than that of conventional chest X-ray of 79.31%.P<0.05).The difference was statistically significant(P<0.05).Conclusion:Spiral CT chest enhanced scan can not only find special tuberculosis lesions that cannot be detected by conventional chest radiography,but also accurately determine active pulmonary tuberculosis in adults,which is of high diagnostic value.展开更多
Objective:To investigate the diagnostic effects of enhanced CT scan on hemorrhage corpus luteum cyst(HCLC).Methods:The clinical data of 24 patients with hemorrhage corpus luteum cyst diagnosed by surgery and pathology...Objective:To investigate the diagnostic effects of enhanced CT scan on hemorrhage corpus luteum cyst(HCLC).Methods:The clinical data of 24 patients with hemorrhage corpus luteum cyst diagnosed by surgery and pathology in our hospital were collected.All patients received enhanced CT scan to evaluate the diagnostic value of CT.Results:The average diameter of the cysts in this group of patients was 5.1cm by CT.Further detection of the ruptured cyst wall showed that there was a liquid lowdensity shadow.Some of the cysts were accompanied by signs of increased density,indicating the presence of blood clots;all patients received surgical treatment.Intraoperative ultrasound examination of the cysts had an average diameter of 5.2cm and a wall of 0.2~0.4mm.Among them,19 cases of cysts contained"coffee-colored"liquid with varying degrees of blood clots,and 5 cases had no blood clots in the cysts but there were a lot of blood clots beside the cysts.Conclusion:The application of enhanced CT scan in patients with hemorrhage corpus luteum cyst is of great value.It can provide accurate data reference for clinical treatment and is worthy of promoting its clinical application.展开更多
Objective: to investigate the application value of enhanced CT delayed scan in differential diagnosis of liver tumors. Methods: in this paper, 102 patients with liver tumor who were enrolled in a hospital in this city...Objective: to investigate the application value of enhanced CT delayed scan in differential diagnosis of liver tumors. Methods: in this paper, 102 patients with liver tumor who were enrolled in a hospital in this city from January 2020 to March 2021 were analyzed and studied. All patients received CT enhanced time-delay scan to analyze the influence of CT on manifestations and to study and analyze the diagnostic results. Results: the difference between the results of enhanced delayed CT scanning and pathological diagnosis was only about 10%. Conclusion: CT enhanced delayed scanning has good safety and high diagnostic accuracy in the diagnosis of liver tumors, which has clinical application value.展开更多
Objective: to analyze the role of dynamic magnetic resonance enhancement in imaging diagnosis of early hepatocellular carcinoma. Methods: sixty-two patients with hepatocytic lesions who were enrolled in our hospital f...Objective: to analyze the role of dynamic magnetic resonance enhancement in imaging diagnosis of early hepatocellular carcinoma. Methods: sixty-two patients with hepatocytic lesions who were enrolled in our hospital from June 2019 to June 2020 were selected as the research subjects. All patients were examined by dynamic enhanced CT scan and liver MRI. The diagnostic results of the two different methods were analyzed based on pathological examination, and their diagnostic value was compared. Conclusion: liver MRI examination in patients with HCC has relatively high sensitivity and specificity, and excellent application effect, which can provide accurate basis for early diagnosis and later targeted treatment by doctors, and is worthy of clinical application and vigorous promotion.展开更多
Objective: to study the diagnostic value of solitary pulmonary nodules on dynamic enhancement of CT scan. Methods: the clinical data of 100 patients with solitary pulmonary nodules in our hospital from January 2018 to...Objective: to study the diagnostic value of solitary pulmonary nodules on dynamic enhancement of CT scan. Methods: the clinical data of 100 patients with solitary pulmonary nodules in our hospital from January 2018 to December 2020 were analyzed retrospectively. All patients underwent dynamic enhancement of CT scanning, and the results of pathological examination and CT scanning were compared and analyzed. Results: in the comparison between dynamic enhancement of CT scan and pathological examination, 95.83% were the diagnostic coincidence rate of malignant pulmonary nodules and 93.33% were benign pulmonary nodules. The coincidence rate of benign and malignant pulmonary nodules before and after enhanced scan was significantly lower than that after enhanced scan (P < 0.05);There was significant difference in CT value between benign and malignant pulmonary nodules (P < 0.05). Conclusion: in the differential diagnosis and diagnosis of solitary pulmonary nodules by dynamic contrast-enhanced CT scanning, it is worthy of clinical application and has high application value.展开更多
BACKGROUND: Surgeons are always concerned about the localization of pancreatic functioning islet cell tumor. If the tumor is accurately localized before operation, resection of the pancreatic body and tail without int...BACKGROUND: Surgeons are always concerned about the localization of pancreatic functioning islet cell tumor. If the tumor is accurately localized before operation, resection of the pancreatic body and tail without intention can be avoided. The purpose of this study was to evaluate spiral CT localization of pancreatic functioning islet cell tumors and CT techniques. METHODS: CT manifestations in 6 patients with clinically and pathologically proved pancreatic functioning islet cell tumors ware analyzed retrospectively. RESULTS: In 4 patients with insulinomas and 2 patients with glucagonomas, 5 were localized accurately by CT be- fore surgery and 1 was detected retrospectively. The en- hancement of tumors was greater than that of normal pan- creas in arterial phase and pancreatic parenchymal phase. Four patients showed mild high-density and 2, iso-density in the portal venous phase. CONCLUSION: Spiral CT multi-phase enhanced scan with 1.5 ml/kg contrast agent and 2-5 mm slice width can loca- lize functioning islet cell tumors accurately.展开更多
An efficient design-for-testability (DFT) technique is proposed to achieve low overhead for scan-based delay fault testing. Existing techniques for delay test such as skewed-load or broadside make the test generatio...An efficient design-for-testability (DFT) technique is proposed to achieve low overhead for scan-based delay fault testing. Existing techniques for delay test such as skewed-load or broadside make the test generation process complex and produce lower coverage for scan-based designs as compared with non-scan designs, whereas techniques such as enhanced-scan test can make the test easy but need an extra holding latch to add substantial hardware overhead. A new tri-state holding logic is presented to replace the common holding latch in enhanced-scan test to get a substantial low hardware overhead. This scheme can achieve low delay overhead by avoiding the holding latch on the critical timing scan path. What's more, this method can also keep the state and signal activity in the combinational circuit from the scan during data scan-in operation to reduce the power dissipation. Experiment results on a set of ISCAS89 benchmarks show the efficiency of the proposed scheme.展开更多
Objectives: To evaluate the specific manifestations of pancreatic carcinoma on spiral multi-phase CT and its resectability before operation. Methods: Ninety-seven patients were confirmed oper- atively and pathological...Objectives: To evaluate the specific manifestations of pancreatic carcinoma on spiral multi-phase CT and its resectability before operation. Methods: Ninety-seven patients were confirmed oper- atively and pathologically. Enhanced CT scan was performed with intravenous injection bolus of ap- proximately 75-120 ml (1-1.5 ml/kg body weight) contrast medium at a rate of 2.5-3 ml/s. In 68 pa- tients receiving dual-phase scan, the delayed scan time of arterial and venous phases was 18-20 s and 60-70 s, respectively, and in 29 patients receiving three-phase scan, the delayed scan time of arterial, pancreatic and portal venous phases was 18 s, 40 s and 75 s, respectively, with a slice of 3-5 mm thick- ness, a pitch of 1-1.5, and a reconstruction interval of 2.5-4.8 mm. Results: Positive and negative predictive values of un- resectable tumors were 97.65% and 75.86%, respec- tively. The sensitivity and accuracy were 90.67% and 90. 72%, respectively. Positive predictive values of dual-phase and three-phase were 95.83% and 100%, respectively; negative predictive values were 75% and 77.78%, respectively. Conclusions: Spiral multi-phase CT is superior in re- vealing the involvement of peripancreatic vessels, the invasion of the neighboring organs, the size, shape and range of carcinoma, and the metastasis of liver and lymph node. The predictability of resection is obviously increased for patients with pancreatic car- cinoma.展开更多
In optical scanning holography, one pupil produces a spherical wave and another produces a plane wave. They interfere with each other and result in a fringe pattern for scanning a three-dimensional object. The resolut...In optical scanning holography, one pupil produces a spherical wave and another produces a plane wave. They interfere with each other and result in a fringe pattern for scanning a three-dimensional object. The resolution of the hologram reconstruction is affected by the point spread function(PSF) of the optical system. In this paper, we modulate the PSF by a spiral phase plate, which significantly enhances the lateral and depth resolution. We explain the theory for such resolution enhancement and show simulation results to verify the efficacy of the approach.展开更多
Background:A uterine leiomyosarcoma is a relatively rare malignant tumor of the uterus with a high degree of malignancy that is prone to distant metastasis and recurrence in the early stages,and therefore has a poor p...Background:A uterine leiomyosarcoma is a relatively rare malignant tumor of the uterus with a high degree of malignancy that is prone to distant metastasis and recurrence in the early stages,and therefore has a poor prognosis.Plain and enhanced CT scans are important for the early diagnosis of uterine leiomyosarcoma.Case report:We report the case of a 47-year-old woman with a uterine leiomyosarcoma.A preoperative plain CT scan showed significant uterine enlargement,whereas an enhanced CT scan showed an uneven and significantly enhanced mass.A large mass was observed in the lower and middle parts of the abdomen intraoperatively.The large mass in the abdominal and pelvic cavities was a uterine mass with bilateral adnexal lesions,approximately 20 cm×20 cm×15 cm in size.Bilateral retroperitoneal masses were palpated.A total hysterectomy,left salpingectomy,right adnexectomy,and resection of the retroperitoneal mass were performed.The pathologic diagnosis was uterine leiomyosarcoma with bleeding and necrosis.Conclusions:Diagnosis of uterine leiomyosarcoma lacks clinical specificity.Imaging is helpful for early diagnosis,treatment,disease course assessment,and efficacy evaluation.Ultimately,a pathologic examination and biopsy are required to confirm the diagnosis.展开更多
Background Quantitative dynamic contrast enhancement MR imaging (DCE-MRI),used to measure properties of tissue microvasculature and tumor angiogenesis,is a promising method for distinguishing benign and malignant tu...Background Quantitative dynamic contrast enhancement MR imaging (DCE-MRI),used to measure properties of tissue microvasculature and tumor angiogenesis,is a promising method for distinguishing benign and malignant tumors and characterizing tumor response to antiangiogenic treatment.The aim of this study was to assess the feasibility of quantitative parameters derived from clinically used DCE-MRI for distinguishing benign from malignant tumors in the sinonasal area,which may be potentially useful for prediction and monitoring of treatment response to chemoradiotherapy of sinonasal tumors.Methods One hundred and forty-three patients with sinonasal tumors,including 78 malignant tumors and 65 benign tumors and tumor-like lesions,underwent clinically used DCE-MRI.Parametric maps were obtained for quantitative parameters including Ktrans,kep and ve.Two radiologists reviewed these maps and measured Ktrans,kep and ve in the tumor tissue.Data were analyzed using independent T-test or Mann-Whitney U test analysis and receiver operating characteristic curves.Results Ktrans,kep and ve showed significant differences between benign and malignant tumors in the sinonasal area (P=-0.000 1).The accuracy of Ktrans,kep and ve in differentiation between benign and malignant sinonasal tumors were 72.0%,76.2% and 67.1%,respectively.There were significant differences in kep and ve between malignant epithelial sinonasal tumors and lymphomas (P <0.05).Using a ve value of 0.213 as the threshold value differentiated malignant epithelial tumors from lymphomas with an accuracy of 78.3%,sensitivity of 88.2%,specificity of 68.0%,positive predictive value of 66.7%,and negative predictive value of 90.9%.However,no significant difference in Ktrans and kep was found between malignant epithelial and non-epithelial tumors in the sinonasal area (P >0.05).Conclusions It is feasible that quantitative parameters of tumors can be derived from clinically used DCE-MRI in the sinonasal region.Preliminary findings suggest an increased value for quantitative DCE-MRI in the evaluation of sinonasal tumors in clinical practice.展开更多
基金Health and Family Planning Commission of Zigong(No.2017wZCS09)
文摘Objective:To study the correlation between CT dynamic enhanced scanning parameters and serum tumor markers before and after radiofrequency ablation in patients with lung cancer.Methods:60 patients with advanced non-small cell lung cancer who were treated in this hospital between January 2015 and January 2017 were divided into control group(n=30)and observation group(n=30)by random number table method.Control group received conventional intravenous chemotherapy,and observation group received intravenous chemotherapy combined with radiofrequency ablation.The differences in CT dynamic enhanced scanning parameter levels and serum tumor marker contents were compared between the two groups of patients before and after treatment.Pearson test was used to evaluate the correlation between CT dynamic enhanced scanning parameters and serum tumor marker contents in patients with advanced non-small cell lung cancer.Results:Before treatment,the differences in CT dynamic enhanced scanning parameter levels,non-organ-specific tumor marker contents and vascular tumor marker contents were not statistically significant between the two groups of patients(P>0.05).After treatment,CT dynamic enhanced scanning parameters PH and perfusion value levels of observation group were lower than those of control group(P<0.05);serum non-organ specific tumor markers CA125,CA153,CEA and CYFRA21-1 contents of observation group were lower than those of control group;serum vascular tumor markers VEGF,Ang-2,HIF-1 and MMP-9 contents were lower than those of control group(P<0.05).Pearson test showed that CT dynamic enhanced scanning parameters PH and perfusion value levels in patients with non-small cell lung cancer were positively correlated with serum non-organ specific tumor marker and vascular tumor marker contents.Conclusion:Adjuvant radiofrequency ablation can significantly reduce the tumor malignancy of patients with advanced non-small cell lung cancer.
文摘Insulinomas are the most common category of pancreatic endocrine tumors,with an annual incidence of 1-4 cases per million people.Most are intrapancreatic,benign and solitary.Therefore,they have an excellent prognosis after surgical resection.However,the localization diagnosis of insulinomas still poses a challenge to surgeons and radiologists.In this case,the tumor was occult and could not be found by either abdominal enhanced spiral computed tomography(CT)or ultrasonography.Therefore,we tried a new method of CT scanning and localized the tumor.
文摘Aim:To explore the diagnostic value of spiral CT chest enhanced scan for adults with active pulmonary tuberculosis.Methods:The clinical data of 60 adult patients with active pulmonary tuberculosis who were treated in our hospital from January 2018 to November 2019 were retrospectively analyzed.All patients underwent conventional chest radiography and spiral CT chest enhanced scan.The number of tuberculosis diagnosis,the detection rate of special site lesions,and the detection rate of active pulmonary tuberculosis signs by the two methods were compared.Results:In 60 patients,the pathological results confirmed the existence of 75 tuberculosis lesions.The detection rate of spiral CT was 98.67%,which was not statistically significant compared with the detection rate of 92.00%(P>0.05)in the conventional chest X-ray.The detection rate of spiral CT enhanced scans for tuberculosis lesions in special sites was 100.00%,which was significantly higher than that of conventional chest X-ray of 7.69%,and the accuracy rate of active pulmonary tuberculosis signs was 98.85%higher than that of conventional chest X-ray of 79.31%.P<0.05).The difference was statistically significant(P<0.05).Conclusion:Spiral CT chest enhanced scan can not only find special tuberculosis lesions that cannot be detected by conventional chest radiography,but also accurately determine active pulmonary tuberculosis in adults,which is of high diagnostic value.
文摘Objective:To investigate the diagnostic effects of enhanced CT scan on hemorrhage corpus luteum cyst(HCLC).Methods:The clinical data of 24 patients with hemorrhage corpus luteum cyst diagnosed by surgery and pathology in our hospital were collected.All patients received enhanced CT scan to evaluate the diagnostic value of CT.Results:The average diameter of the cysts in this group of patients was 5.1cm by CT.Further detection of the ruptured cyst wall showed that there was a liquid lowdensity shadow.Some of the cysts were accompanied by signs of increased density,indicating the presence of blood clots;all patients received surgical treatment.Intraoperative ultrasound examination of the cysts had an average diameter of 5.2cm and a wall of 0.2~0.4mm.Among them,19 cases of cysts contained"coffee-colored"liquid with varying degrees of blood clots,and 5 cases had no blood clots in the cysts but there were a lot of blood clots beside the cysts.Conclusion:The application of enhanced CT scan in patients with hemorrhage corpus luteum cyst is of great value.It can provide accurate data reference for clinical treatment and is worthy of promoting its clinical application.
文摘Objective: to investigate the application value of enhanced CT delayed scan in differential diagnosis of liver tumors. Methods: in this paper, 102 patients with liver tumor who were enrolled in a hospital in this city from January 2020 to March 2021 were analyzed and studied. All patients received CT enhanced time-delay scan to analyze the influence of CT on manifestations and to study and analyze the diagnostic results. Results: the difference between the results of enhanced delayed CT scanning and pathological diagnosis was only about 10%. Conclusion: CT enhanced delayed scanning has good safety and high diagnostic accuracy in the diagnosis of liver tumors, which has clinical application value.
文摘Objective: to analyze the role of dynamic magnetic resonance enhancement in imaging diagnosis of early hepatocellular carcinoma. Methods: sixty-two patients with hepatocytic lesions who were enrolled in our hospital from June 2019 to June 2020 were selected as the research subjects. All patients were examined by dynamic enhanced CT scan and liver MRI. The diagnostic results of the two different methods were analyzed based on pathological examination, and their diagnostic value was compared. Conclusion: liver MRI examination in patients with HCC has relatively high sensitivity and specificity, and excellent application effect, which can provide accurate basis for early diagnosis and later targeted treatment by doctors, and is worthy of clinical application and vigorous promotion.
文摘Objective: to study the diagnostic value of solitary pulmonary nodules on dynamic enhancement of CT scan. Methods: the clinical data of 100 patients with solitary pulmonary nodules in our hospital from January 2018 to December 2020 were analyzed retrospectively. All patients underwent dynamic enhancement of CT scanning, and the results of pathological examination and CT scanning were compared and analyzed. Results: in the comparison between dynamic enhancement of CT scan and pathological examination, 95.83% were the diagnostic coincidence rate of malignant pulmonary nodules and 93.33% were benign pulmonary nodules. The coincidence rate of benign and malignant pulmonary nodules before and after enhanced scan was significantly lower than that after enhanced scan (P < 0.05);There was significant difference in CT value between benign and malignant pulmonary nodules (P < 0.05). Conclusion: in the differential diagnosis and diagnosis of solitary pulmonary nodules by dynamic contrast-enhanced CT scanning, it is worthy of clinical application and has high application value.
文摘BACKGROUND: Surgeons are always concerned about the localization of pancreatic functioning islet cell tumor. If the tumor is accurately localized before operation, resection of the pancreatic body and tail without intention can be avoided. The purpose of this study was to evaluate spiral CT localization of pancreatic functioning islet cell tumors and CT techniques. METHODS: CT manifestations in 6 patients with clinically and pathologically proved pancreatic functioning islet cell tumors ware analyzed retrospectively. RESULTS: In 4 patients with insulinomas and 2 patients with glucagonomas, 5 were localized accurately by CT be- fore surgery and 1 was detected retrospectively. The en- hancement of tumors was greater than that of normal pan- creas in arterial phase and pancreatic parenchymal phase. Four patients showed mild high-density and 2, iso-density in the portal venous phase. CONCLUSION: Spiral CT multi-phase enhanced scan with 1.5 ml/kg contrast agent and 2-5 mm slice width can loca- lize functioning islet cell tumors accurately.
基金This project was supported by the National Natural Science Foundation of China (90407007).
文摘An efficient design-for-testability (DFT) technique is proposed to achieve low overhead for scan-based delay fault testing. Existing techniques for delay test such as skewed-load or broadside make the test generation process complex and produce lower coverage for scan-based designs as compared with non-scan designs, whereas techniques such as enhanced-scan test can make the test easy but need an extra holding latch to add substantial hardware overhead. A new tri-state holding logic is presented to replace the common holding latch in enhanced-scan test to get a substantial low hardware overhead. This scheme can achieve low delay overhead by avoiding the holding latch on the critical timing scan path. What's more, this method can also keep the state and signal activity in the combinational circuit from the scan during data scan-in operation to reduce the power dissipation. Experiment results on a set of ISCAS89 benchmarks show the efficiency of the proposed scheme.
基金This study was supported by the grant from the Program of Social Development Fund of the Jiangsu Provincial Science and Technology Commission (BS97046).
文摘Objectives: To evaluate the specific manifestations of pancreatic carcinoma on spiral multi-phase CT and its resectability before operation. Methods: Ninety-seven patients were confirmed oper- atively and pathologically. Enhanced CT scan was performed with intravenous injection bolus of ap- proximately 75-120 ml (1-1.5 ml/kg body weight) contrast medium at a rate of 2.5-3 ml/s. In 68 pa- tients receiving dual-phase scan, the delayed scan time of arterial and venous phases was 18-20 s and 60-70 s, respectively, and in 29 patients receiving three-phase scan, the delayed scan time of arterial, pancreatic and portal venous phases was 18 s, 40 s and 75 s, respectively, with a slice of 3-5 mm thick- ness, a pitch of 1-1.5, and a reconstruction interval of 2.5-4.8 mm. Results: Positive and negative predictive values of un- resectable tumors were 97.65% and 75.86%, respec- tively. The sensitivity and accuracy were 90.67% and 90. 72%, respectively. Positive predictive values of dual-phase and three-phase were 95.83% and 100%, respectively; negative predictive values were 75% and 77.78%, respectively. Conclusions: Spiral multi-phase CT is superior in re- vealing the involvement of peripancreatic vessels, the invasion of the neighboring organs, the size, shape and range of carcinoma, and the metastasis of liver and lymph node. The predictability of resection is obviously increased for patients with pancreatic car- cinoma.
基金supported in part by the Research Grants Council of the Hong Kong Special Administrative Region,China, under project 7131–12Ethe NSFC RGC grant under project N–HKU714–13
文摘In optical scanning holography, one pupil produces a spherical wave and another produces a plane wave. They interfere with each other and result in a fringe pattern for scanning a three-dimensional object. The resolution of the hologram reconstruction is affected by the point spread function(PSF) of the optical system. In this paper, we modulate the PSF by a spiral phase plate, which significantly enhances the lateral and depth resolution. We explain the theory for such resolution enhancement and show simulation results to verify the efficacy of the approach.
基金supported by the National Natural Science Foundation of China(82160348 to BY)the Major Science and Technology Special Plan Project of Yunnan Provincial Department of Science and Technology(202302AA3100018 to BY)the Kunming Health Technology Talent Training Project(2022-SW(Reserve)-01 to BY).
文摘Background:A uterine leiomyosarcoma is a relatively rare malignant tumor of the uterus with a high degree of malignancy that is prone to distant metastasis and recurrence in the early stages,and therefore has a poor prognosis.Plain and enhanced CT scans are important for the early diagnosis of uterine leiomyosarcoma.Case report:We report the case of a 47-year-old woman with a uterine leiomyosarcoma.A preoperative plain CT scan showed significant uterine enlargement,whereas an enhanced CT scan showed an uneven and significantly enhanced mass.A large mass was observed in the lower and middle parts of the abdomen intraoperatively.The large mass in the abdominal and pelvic cavities was a uterine mass with bilateral adnexal lesions,approximately 20 cm×20 cm×15 cm in size.Bilateral retroperitoneal masses were palpated.A total hysterectomy,left salpingectomy,right adnexectomy,and resection of the retroperitoneal mass were performed.The pathologic diagnosis was uterine leiomyosarcoma with bleeding and necrosis.Conclusions:Diagnosis of uterine leiomyosarcoma lacks clinical specificity.Imaging is helpful for early diagnosis,treatment,disease course assessment,and efficacy evaluation.Ultimately,a pathologic examination and biopsy are required to confirm the diagnosis.
基金This work was supported by grants from Beijing Excellent Talents Foundation (No.2010D003034000033),Beijing Municipal Natural Science Foundation (No.7112030),High Levels of Health Technical Personnel in Beijing City (No.2011-3-047) and China Postdoctoral Science Foundation (No.2011M500026).
文摘Background Quantitative dynamic contrast enhancement MR imaging (DCE-MRI),used to measure properties of tissue microvasculature and tumor angiogenesis,is a promising method for distinguishing benign and malignant tumors and characterizing tumor response to antiangiogenic treatment.The aim of this study was to assess the feasibility of quantitative parameters derived from clinically used DCE-MRI for distinguishing benign from malignant tumors in the sinonasal area,which may be potentially useful for prediction and monitoring of treatment response to chemoradiotherapy of sinonasal tumors.Methods One hundred and forty-three patients with sinonasal tumors,including 78 malignant tumors and 65 benign tumors and tumor-like lesions,underwent clinically used DCE-MRI.Parametric maps were obtained for quantitative parameters including Ktrans,kep and ve.Two radiologists reviewed these maps and measured Ktrans,kep and ve in the tumor tissue.Data were analyzed using independent T-test or Mann-Whitney U test analysis and receiver operating characteristic curves.Results Ktrans,kep and ve showed significant differences between benign and malignant tumors in the sinonasal area (P=-0.000 1).The accuracy of Ktrans,kep and ve in differentiation between benign and malignant sinonasal tumors were 72.0%,76.2% and 67.1%,respectively.There were significant differences in kep and ve between malignant epithelial sinonasal tumors and lymphomas (P <0.05).Using a ve value of 0.213 as the threshold value differentiated malignant epithelial tumors from lymphomas with an accuracy of 78.3%,sensitivity of 88.2%,specificity of 68.0%,positive predictive value of 66.7%,and negative predictive value of 90.9%.However,no significant difference in Ktrans and kep was found between malignant epithelial and non-epithelial tumors in the sinonasal area (P >0.05).Conclusions It is feasible that quantitative parameters of tumors can be derived from clinically used DCE-MRI in the sinonasal region.Preliminary findings suggest an increased value for quantitative DCE-MRI in the evaluation of sinonasal tumors in clinical practice.