Enamel,the inorganic tissue covering the crowns of teeth,is known for its remarkable resilience and hardness.These properties originate from its high proportion of mineralized matrix and complex internal microarchitec...Enamel,the inorganic tissue covering the crowns of teeth,is known for its remarkable resilience and hardness.These properties originate from its high proportion of mineralized matrix and complex internal microarchitecture.On an ultrastructural level,it consists of directionally arranged enamel prisms.Continuously growing rodent incisors are an exemplary case of this phenomenon.Their enamel has a consistent decussation pattern,providing teeth with extremely high resistance and ensuring they remain constantly sharp.While the decussation pattern has been described in detail,mechanisms behind its formation have not been experimentally proven.Here,we show that the highly organized enamel micropattern is generated by directional epithelial sliding of enamel-forming ameloblasts in vivo.Our results detail how enamel micropatterning stems from individual cell cluster segregation and subsequent reciprocal interweaving.Based on this determination,we introduce and experimentally demonstrate a new model of enamel decussation pattern formation.展开更多
Enamel demineralization,the formation of white spot lesions,is a common issue in clinical orthodontic treatment.The appearance of white spot lesions not only affects the texture and health of dental hard tissues but a...Enamel demineralization,the formation of white spot lesions,is a common issue in clinical orthodontic treatment.The appearance of white spot lesions not only affects the texture and health of dental hard tissues but also impacts the health and aesthetics of teeth after orthodontic treatment.The prevention,diagnosis,and treatment of white spot lesions that occur throughout the orthodontic treatment process involve multiple dental specialties.This expert consensus will focus on providing guiding opinions on the management and prevention of white spot lesions during orthodontic treatment,advocating for proactive prevention,early detection,timely treatment,scientific follow-up,and multidisciplinary management of white spot lesions throughout the orthodontic process,thereby maintaining the dental health of patients during orthodontic treatment.展开更多
Enamel demineralization often occurs in the early stage of dental caries.Studying the microscopic mechanism of enamel demineralization is essential to prevent and treat dental caries.Terahertz(THz)technolo⁃gy,especial...Enamel demineralization often occurs in the early stage of dental caries.Studying the microscopic mechanism of enamel demineralization is essential to prevent and treat dental caries.Terahertz(THz)technolo⁃gy,especially continuous wave(CW)THz near-field scanning microscopy(THz-SNOM)with its nanoscale reso⁃lution,can be promising in biomedical imaging.In addition,compared with traditional THz time-domain spec⁃troscopy(TDS),portable solid-state source as the emission has higher power and SNR,lower cost,and can ob⁃tain more precise imaging.In this study,we employ CW THz-SNOM to further break the resolution limitations of conventional THz imaging techniques and successfully achieve the near-field imaging of demineralized enamel at the nanoscale.We keenly observe that the near-field signal of the enamel significantly lowers as demineralization deepens,mainly due to the decrease in permittivity.This new approach offers valuable insights into the micro⁃scopic processes of enamel demineralization,laying the foundation for further research and treatment.展开更多
From June 3 to June 7,2025,the"Enamel Art Exhibition:The Evolution from Jingtailan to Contemporary Artworks"and related events took place at China Cultural Center in Madrid.The exhibition showcased Chinese e...From June 3 to June 7,2025,the"Enamel Art Exhibition:The Evolution from Jingtailan to Contemporary Artworks"and related events took place at China Cultural Center in Madrid.The exhibition showcased Chinese enamel art in Spain,facilitating the exchange of professional techniques and concepts,as well as public dissemination and popularization.展开更多
The objective of this investigation is to explore the region-dependent damage behavior of enamel, as well as to develop a good understanding of the deformation mech- anisms of enamel with numerical modeling. Nanoinden...The objective of this investigation is to explore the region-dependent damage behavior of enamel, as well as to develop a good understanding of the deformation mech- anisms of enamel with numerical modeling. Nanoinden- tation experiments have been performed to investigate the load-penetration depth responses for outer and inner enamel. Results show that the unloading curve does not follow the loading curve, and degradation of stiffness in the unloading curve is observed. Based on the experimental data, a physi- cal quantity, the chain density in protein, has been introduced to the Drucker-Prager plastic model. Numerical simulations show that the simulated load-penetration depth curves agree with the experiments, and the stiffness degradation behav- iors of outer and inner enamel are captured by the numerical model. The region-dependent damage behavior of enamel could be revealed by the numerical model. The micro dam- age affected area at inner enamel is larger than that at outer enamel, indicating that the inner enamel experiences more micro damage than the outer one. Compared with its outer counterpart, the inner enamel which is rich in organic protein could break more internal protein chains to dissipate energy and to enhance its resistance to fracture accordingly.展开更多
Inside the exhibition hall of the 2025 Osaka World Expo in Japan,crowds gathered before a cloisonne enamel painting titled The Pomegranate of Ethnic Unity.The pomegranate,outlined with gold filigree,appears full and r...Inside the exhibition hall of the 2025 Osaka World Expo in Japan,crowds gathered before a cloisonne enamel painting titled The Pomegranate of Ethnic Unity.The pomegranate,outlined with gold filigree,appears full and ripe;Tibetan auspicious motifs intertwine with Han-style cloud patterns,and the enamel glaze reflects brilliant colors under the lights.Created by teachers and students from Nyingchi Vocational and Technical School(hereafter“Nyingchi Vocational School”),this artwork not only drew admiration from countless visitors but also became a“silent envoy”of dialogue between Tibetan culture and the world.展开更多
基金supported by the Czech Science Foundation (23-06160S)by the Faculty of Medicine of Masaryk University (MUNI/A/1738/2024)。
文摘Enamel,the inorganic tissue covering the crowns of teeth,is known for its remarkable resilience and hardness.These properties originate from its high proportion of mineralized matrix and complex internal microarchitecture.On an ultrastructural level,it consists of directionally arranged enamel prisms.Continuously growing rodent incisors are an exemplary case of this phenomenon.Their enamel has a consistent decussation pattern,providing teeth with extremely high resistance and ensuring they remain constantly sharp.While the decussation pattern has been described in detail,mechanisms behind its formation have not been experimentally proven.Here,we show that the highly organized enamel micropattern is generated by directional epithelial sliding of enamel-forming ameloblasts in vivo.Our results detail how enamel micropatterning stems from individual cell cluster segregation and subsequent reciprocal interweaving.Based on this determination,we introduce and experimentally demonstrate a new model of enamel decussation pattern formation.
基金funded with National Key R&D Program of China(2022YFC2405904)National Natural Science Foundation of China(11932012,and 32171348).
文摘Enamel demineralization,the formation of white spot lesions,is a common issue in clinical orthodontic treatment.The appearance of white spot lesions not only affects the texture and health of dental hard tissues but also impacts the health and aesthetics of teeth after orthodontic treatment.The prevention,diagnosis,and treatment of white spot lesions that occur throughout the orthodontic treatment process involve multiple dental specialties.This expert consensus will focus on providing guiding opinions on the management and prevention of white spot lesions during orthodontic treatment,advocating for proactive prevention,early detection,timely treatment,scientific follow-up,and multidisciplinary management of white spot lesions throughout the orthodontic process,thereby maintaining the dental health of patients during orthodontic treatment.
基金Supported by the National Natural Science Foundation of China(61988102,62401113,92463308)。
文摘Enamel demineralization often occurs in the early stage of dental caries.Studying the microscopic mechanism of enamel demineralization is essential to prevent and treat dental caries.Terahertz(THz)technolo⁃gy,especially continuous wave(CW)THz near-field scanning microscopy(THz-SNOM)with its nanoscale reso⁃lution,can be promising in biomedical imaging.In addition,compared with traditional THz time-domain spec⁃troscopy(TDS),portable solid-state source as the emission has higher power and SNR,lower cost,and can ob⁃tain more precise imaging.In this study,we employ CW THz-SNOM to further break the resolution limitations of conventional THz imaging techniques and successfully achieve the near-field imaging of demineralized enamel at the nanoscale.We keenly observe that the near-field signal of the enamel significantly lowers as demineralization deepens,mainly due to the decrease in permittivity.This new approach offers valuable insights into the micro⁃scopic processes of enamel demineralization,laying the foundation for further research and treatment.
文摘From June 3 to June 7,2025,the"Enamel Art Exhibition:The Evolution from Jingtailan to Contemporary Artworks"and related events took place at China Cultural Center in Madrid.The exhibition showcased Chinese enamel art in Spain,facilitating the exchange of professional techniques and concepts,as well as public dissemination and popularization.
基金supported by the National Natural Science Foundation of China(11172161)the Science and Technology Commission of Shanghai Municipality(10410701900,11195820900 and 10ZR1423400)+2 种基金the Innovation Program of Shanghai Municipal Education Commission(12ZZ092)the State Key Laboratory of Oral Diseases(Sichuan University)(SKLODSCU2009KF03)the Shanghai Leading Academic Discipline Project(S30106)
文摘The objective of this investigation is to explore the region-dependent damage behavior of enamel, as well as to develop a good understanding of the deformation mech- anisms of enamel with numerical modeling. Nanoinden- tation experiments have been performed to investigate the load-penetration depth responses for outer and inner enamel. Results show that the unloading curve does not follow the loading curve, and degradation of stiffness in the unloading curve is observed. Based on the experimental data, a physi- cal quantity, the chain density in protein, has been introduced to the Drucker-Prager plastic model. Numerical simulations show that the simulated load-penetration depth curves agree with the experiments, and the stiffness degradation behav- iors of outer and inner enamel are captured by the numerical model. The region-dependent damage behavior of enamel could be revealed by the numerical model. The micro dam- age affected area at inner enamel is larger than that at outer enamel, indicating that the inner enamel experiences more micro damage than the outer one. Compared with its outer counterpart, the inner enamel which is rich in organic protein could break more internal protein chains to dissipate energy and to enhance its resistance to fracture accordingly.
文摘Inside the exhibition hall of the 2025 Osaka World Expo in Japan,crowds gathered before a cloisonne enamel painting titled The Pomegranate of Ethnic Unity.The pomegranate,outlined with gold filigree,appears full and ripe;Tibetan auspicious motifs intertwine with Han-style cloud patterns,and the enamel glaze reflects brilliant colors under the lights.Created by teachers and students from Nyingchi Vocational and Technical School(hereafter“Nyingchi Vocational School”),this artwork not only drew admiration from countless visitors but also became a“silent envoy”of dialogue between Tibetan culture and the world.
