BACKGROUND Ulcerative colitis(UC)is a chronic and debilitating inflammatory bowel disease.Cumulative evidence indicates that excess hydrogen peroxide,a potent neutrophilic chemotactic agent,produced by colonic epithel...BACKGROUND Ulcerative colitis(UC)is a chronic and debilitating inflammatory bowel disease.Cumulative evidence indicates that excess hydrogen peroxide,a potent neutrophilic chemotactic agent,produced by colonic epithelial cells has a causal role leading to infiltration of neutrophils into the colonic mucosa and subsequent development of UC.This evidence-based mechanism identifies hydrogen peroxide as a therapeutic target for reducing agents in the treatment of UC.CASE SUMMARY Presented is a 41-year-old female with a 26-year history of refractory UC.Having developed steroid dependence and never achieving complete remission on treatment by conventional and advanced therapies,she began treatment with oral R-dihydrolipoic acid(RDLA),a lipid-soluble reducing agent with intracellular site of action.Within a week,rectal bleeding ceased.She was asymptomatic for three years until a highly stressful experience,when she noticed blood in her stool.RDLA was discontinued,and she began treatment with oral sodium thiosulfate pentahydrate(STS),a reducing agent with extracellular site of action.After a week,rectal bleeding ceased,and she resumed oral RDLA and discontinued STS.To date,she remains asymptomatic with normal stool calprotectin while on RDLA.CONCLUSION STS and RDLA are reducing agents that serve as highly effective and safe therapy for the induction and maintenance of remission in UC,even in patients refractory or poorly controlled by conventional and advanced therapies.Should preliminary findings be validated by subsequent clinical trials,the use of reducing agents could potentially prevent thousands of colectomies and represent a paradigm shift in the treatment of UC.展开更多
The sulfate-reducing bacteria(SRB)corrosion of H70 brass,H80 brass and T2 copper was systematically studied using microstructure characterizations and electrochemical measurements.The results showed that H70 brass,H80...The sulfate-reducing bacteria(SRB)corrosion of H70 brass,H80 brass and T2 copper was systematically studied using microstructure characterizations and electrochemical measurements.The results showed that H70 brass,H80 brass and T2 copper exhibited good corrosion resistance in the sterile environment,and the corrosion products were mainly metal oxides,such as Cu_(2)O,CuO and ZnO.The SRB metabolism sharply accelerated the corrosion process of three types of copper alloys,especially the T2 copper.In the inoculated environment,an additional mixture of Cu_(2)S,ZnS and CuSO_(4)existed in the corrosion products.Pitting corrosion was the main corrosion style for the H70 brass and H80 brass,while general corrosion and pitting corrosion simultaneously dominated the corrosion process of the T2 copper in this environment.The results provide a new insight to the microbiological corrosion of copper alloys.展开更多
Cement production,while essential for global infrastructure,contributes significantly to carbon dioxide emissions,accounting for approximately 7%of total emissions.To mitigate these environmental impacts,flash calcina...Cement production,while essential for global infrastructure,contributes significantly to carbon dioxide emissions,accounting for approximately 7%of total emissions.To mitigate these environmental impacts,flash calcination of kaolinitic clays has been investigated as a sustainable alternative.This technique involves the rapid heating of clays,enabling their use as supplementary cementitious materials.The primary objective of this study was to modify the color of calcined clay in various atmospheres(oxidizing,inert,and reducing)to achieve a grayish tone similar to commercial cement while preserving its reactive properties.The experimental procedure employed a tubular reactor with precise control of gas flows(atmospheric air,nitrogen,and a carbon monoxide–nitrogen mixture).Physicochemical characterization of the raw clay was conducted before calcination,with analyses repeated on the calcined clays following experimentation.Results indicated that clay calcined in an oxidizing atmosphere acquired a reddish hue,attributed to the oxidation of iron in hematite.The Clay exhibited a pinkish tone in an inert atmosphere,while calcination in a reducing atmosphere yielded the desired grayish color.Regarding pozzolanic activity,clays calcined in oxidizing and inert atmospheres displayed robust strength,ranging from 82%to 87%.Calcination in a reducing atmosphere resulted in slightly lower strength,around 74%,likely due to the clay’s chemical composition and the calcination process,which affects compound formation and material reactivity.展开更多
This study numerically investigates the seismic response of a nine-story self-centering concentrically braced frame building incorporating force-limiting connections between the floor system and the lateral force-resi...This study numerically investigates the seismic response of a nine-story self-centering concentrically braced frame building incorporating force-limiting connections between the floor system and the lateral force-resisting system.Nonlinear earthquake simulations are conducted under design basis earthquake ground motions,and the results are compared against a baseline model with rigid-elastic connections.The study discusses connection design considerations and evaluates the effectiveness of force-limiting connections in mitigating higher-mode effects.The findings show that force-limiting connections significantly reduce the magnitude and variability of floor accelerations,brace forces,and connection forces,while maintaining comparable story drifts.limiting Force-connections primarily reduce the contribution of higher-mode responses,while the controlled rocking base mechanism modifies the first-mode response.Overall,the reduced dispersion in structural response improves the reliability of seismic design and enhances resilience by minimizing damage to both structural components and acceleration-sensitive nonstructural elements.展开更多
Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy se...Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy sector.Methanol plays an important role in the natural gas industry,typically serving as a solvent or hydrate inhibitor.Therefore,the accurate estimation of thermodynamic properties for methane/methanol binary is extremely important to optimise the operating parameter,maximise the dehydration effect,and reduce the cost.As the Helmholtz energy equation of state is expected to offer high accuracy in predicting the vapour-liquid equilibrium of methane/methanol binary,four reducing parameters were derived based on collected experimental data.Additionally,the sensitivities of various reducing parameter combinations were simultaneously investigated.The results demonstrated a strong agreement between predicted fractions and experimental data,with the UMADs(uncertainty-weighted mean absolute deviation)of 3.484 and 0.665 for liquid and vapour phases,respectively.Meanwhile,it is deemed“very likely”,“likely”,and“unlikely”to achieve acceptable prediction for 3-parameter optimisation,2-parameter optimisation and,1-parameter optimisation,respectively.展开更多
Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an ...Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an urgent priority,particularly in low-and middle-income countries(LMICs).This study aimed to evaluate the effectiveness of the Acceptance&Commitment to Empowerment:Linking Youths AND‘Xin’(Hearts)(ACE-LYNX)intervention in reducing stigma,improving psychological well-being,and enhancing the MHL and empowerment practices of university mental health providers in China.Methods:A total of 124 trained providers participated in this longitudinal study.Quantitative data were collected at baseline,immediately post-intervention,and three-month follow-up using the validated scale(CAMI,DASS-21)and weekly activity logs recording empowerment practices.Generalized estimating equations(GEEs)and qualitative content analysis were used for data analysis.Results:Quantitative analysis showed a significant reduction in stigma immediately postintervention,particularly in the Social Restriction subscale(β=1.35,p<0.001),though this effect diminished by the 3-month follow-up(β=1.80,p=0.001).Notably,a lasting reduction in the providers’stress levels was maintained.Activity logs showed the highest level of engagement at the individual level(51.4%),followed by group level(32.0%),organizational level(10.5%),and community level(6.1%).Qualitative analysis revealed three themes:Skill-based empowerment enhances professional efficacy,embedded interventions expand service boundaries,and organizational empowerment fosters sustainability.Conclusions:This dual-focus ACE-LYNX intervention effectively improved MHL and both attitudinal and functional competencies among providers.It provides a scalable framework for fostering sustainable and inclusive campus mental health ecosystems,with significant implication for enhance psychological services in resource-constrained educational settings.展开更多
Redox dyshomeostasis is a critical factor in the initiation of numerous diseases,making the accurate evaluation of the redox status of the cellular environment an important aspect of physiological research.However,mai...Redox dyshomeostasis is a critical factor in the initiation of numerous diseases,making the accurate evaluation of the redox status of the cellular environment an important aspect of physiological research.However,maintaining redox homeostasis relies on a complex and dynamic physiological system involving multiple substrate-enzyme interactions,so its accurately detection remains a challenge.With this research,we developed an activable fiuorescence switching platform by incorporating different conjugate acceptors to a fiuorophore using ester bonds and resulting in fiuorescence quenching due to donor-excited photo-induced electron transfer(d-Pe T),which was confirmed through density functional theory calculations.The reaction-based probe was deployed for recognizing all major intracellular reducing sulfur species(RSS),including H_(2)S,cysteine(Cys),homocysteine(Hcy),glutathione(GSH),and protein free thiols.The quenched fiuorescence was significantly recovered by RSS,through releasing the fiuorophore and diminishing the d-Pe T effect.Furthermore,the fiuorescent probe was used for the sensing and imaging RSS in living cells,demonstrating good cell-permeability,low cytotoxicity,and negative correlation with reactive oxygen species content,enabling the evaluating of global thiols redox state in Hep G2 cellular lines during ferroptosis processes.展开更多
In the article“Silencing of the long non-coding RNA LINC00265 triggers autophagy and apoptosis in lung cancer by reducing protein stability of SIN3A oncogene”(Oncology Research.2024,Vol.32,No.7,pp.1185–1195.doi:10....In the article“Silencing of the long non-coding RNA LINC00265 triggers autophagy and apoptosis in lung cancer by reducing protein stability of SIN3A oncogene”(Oncology Research.2024,Vol.32,No.7,pp.1185–1195.doi:10.32604/or.2023.030771,https://www.techscience.com/or/v32n7/57163),an inadvertent error occurred during the compilation of Fig.3H.This needed corrections to ensure the accuracy and integrity of the data presented.展开更多
Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with ca...Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.展开更多
[Objective] The aim was to investigate the effects of plant growth regulators on contents of reducing sugar and starch in potato（Solanum tuberosum L.）.[Method]A potato cultivar named ＇Holand-212＇ with three treatm...[Objective] The aim was to investigate the effects of plant growth regulators on contents of reducing sugar and starch in potato（Solanum tuberosum L.）.[Method]A potato cultivar named ＇Holand-212＇ with three treatments by spraying Diethyl aminoethyl hexanoate（DTA-6）,Uniconazole（S3307）and SOD mimics（SODM）were employed to compare differences of the contents of reducing sugar and starch in potato leaves,stolons and tubers in a field experiment.[Result]DTA-6 treatment could significantly reduce the contents of starch and reducing sugar in potato stolons in the period of 100-110 d after seeding,and it could also reduce the content of reducing sugar in tubers,but there is an opposite result in leaves in the same period,significantly.S3307 could extremely significantly increase the content of starch,and can promote the transfer of starch in stolons,in addition,it also could reduce the content of reducing sugar in tubers,and extremely significantly increase the content of starch in leaves at the 110 d after sowing.Moreover,there is a similar effect between SODM and S3307.[Conclusion]The research results are significant for understanding mechanisms of plant growth regulators and promoting application of plant growth regulator in potato.展开更多
Anyplace where differences are found leaves room for stereotypes.Each of us hears or makes stereotypical comments every day,and although sometimes it is necessary to make stereotypes in foreign language teaching and l...Anyplace where differences are found leaves room for stereotypes.Each of us hears or makes stereotypical comments every day,and although sometimes it is necessary to make stereotypes in foreign language teaching and learning,we should always be aware of the negative effects of stereotyping people from other cultures when we use them to interpret behavior.This paper defines stereotypes,discusses how they impede communication and then focuses on some ways to challenge and reduce stereotypes in cross-cultural communication.展开更多
The effect of reducing agents and surfactants on controlling the silver nanoplates was studied. Two reducing agents, trisodium citrate dehydrate (TSC) and potassium tartrate, were used to reduce the AgNO3 solution. In...The effect of reducing agents and surfactants on controlling the silver nanoplates was studied. Two reducing agents, trisodium citrate dehydrate (TSC) and potassium tartrate, were used to reduce the AgNO3 solution. In this redox system, polyvinylpyrrolidone (PVP), sodium dodecyl sulfate (SDS) and arabic gum were served as surfactants. The results showed that reducing agents and surfactants both act as the capping agent adhering to the certain facets of silver seeds to block this surface to grow. The relative intensity of reducing agents also takes an active part in influencing the growth rate and direction of silver seeds. It was also found that halides can accelerate the speed of Ostwald ripening by adding Cl?, Br? and I?into the aqueous and have some effects on the morphology of the nanoplates.展开更多
Drag reduction phenomenon in pipelines has received lots of attention during the past decades due to its potential engineering applications, especially in fluid transporting industries. Various methods to enhance drag...Drag reduction phenomenon in pipelines has received lots of attention during the past decades due to its potential engineering applications, especially in fluid transporting industries. Various methods to enhance drag reduction have been developed throughout the years and divided into two categories;non-additives method and additives method. Both categories have different types of methods, with different formulations and applications which will generally be discussed in this review. Among all the methods discussed, drag reduction using polymer additive is as one of the most enticing and desirable methods. It has been the subject of research in this field and has been studied extensively for quite some time. It is due to its ability to reduce drag up to 80% when added in minute concentrations. Reducing drag in the pipe will require less pumping power thus offering economic relieves to the industries. So, this paper will be focusing more on the use of polymer additives as drag reducing agent, the general formulations of the additives, major issues involving the use of drag reducing polymers, and the potential applications of it. However, despite the extensive works of drag reduction polymer, there are still no models that accurately explain the mechanism of drag reduction. More studies needed to be done to have a better understanding of the phenomenon. Therefore, future research areas and potential approaches are proposed for future work.展开更多
The morphology and chemical compositions of surface and corrosion phases for two aluminum alloys(7075 and 2024 ) in the aqueous mediums containing sulfate reducing bacteria(SRB) were studied by the methods of scanning...The morphology and chemical compositions of surface and corrosion phases for two aluminum alloys(7075 and 2024 ) in the aqueous mediums containing sulfate reducing bacteria(SRB) were studied by the methods of scanning electron microscopy (SEM) and energy dispersive x ray analysis (EDXA). The results showed that serious pitting corrosion took place when aluminum alloys were exposed in the mediums containing SRB, whereas no pitting corrosion were found on the surfaces of aluminum alloys only exposed in blank mediums non containing SRB. It was demonstrated with EDXA that corrosion of aluminum alloys exposed in the solutions containing SRB, whereas the corrosion in the solution non containing microorganisms was attributed to the presence of chloride ions(Cl ).展开更多
Cities ability reducing earthquake disasters is a complex system involving numerous factors, moreover the re-search on evaluating cities ability reducing earthquake disasters relates to multi-subject, such as earthqua...Cities ability reducing earthquake disasters is a complex system involving numerous factors, moreover the re-search on evaluating cities ability reducing earthquake disasters relates to multi-subject, such as earthquake sci-ence, social science, economical science and so on. In this paper, firstly, the conception of cities ability reducing earthquake disasters is presented, and the ability could be evaluated with three basic elements the possible seis-mic casualty and economic loss during the future earthquakes that are likely to occur in the city and its surround-ings and time required for recovery after earthquake; based upon these three basic elements, a framework, which consists of six main components, for evaluating citys ability reducing earthquake disasters is proposed; then the statistical relations between the index system and the ratio of seismic casualty, the ratio of economic loss and re-covery time are gained utilizing the cities prediction results of earthquake disasters which were made during the ninth five-year plan; at last, the method defining the comprehensive index of cities ability reducing earthquake disasters is presented. Thus the relatively comprehensive theory frame is set up. The frame can evaluate cities ability reducing earthquake disasters absolutely and quantitatively and consequently instruct the decision-making on reducing cities earthquake disasters loss.展开更多
The present study was aimed to assess the ability of Bacillus sp.JDM-2-1 and Staphylococcus capitis to reduce hexavalent chromium into its trivalent form.Bacillus sp.JDM-2-1 could tolerate Cr（Ⅵ）（4800 μg/mL） and ...The present study was aimed to assess the ability of Bacillus sp.JDM-2-1 and Staphylococcus capitis to reduce hexavalent chromium into its trivalent form.Bacillus sp.JDM-2-1 could tolerate Cr（Ⅵ）（4800 μg/mL） and S.capitis could tolerate Cr（Ⅵ）（2800 μg/mL）.Both organisms were able to resist Cd^2＋（50 μg/mL）,Cu^2＋（200 μg/mL）,Pb^2＋（800 μg/mL）,Hg^2＋（50 μg/mL） and Ni2＋（4000 μg/mL）.S.capitis resisted Zn^2＋ at 700 μg/mL while Bacillus sp.JDM-2-1 only showed resistance up to 50 μg/mL.Bacillus sp.JDM-2-1 and S.capitis showed optimum growth at pH 6 and 7,respectively,while both bacteria showed optimum growth at 37°C.Bacillus sp.JDM-2-1 and S.capitis could reduce 85% and 81% of hexavalent chromium from the medium after 96 h and were also capable of reducing hexavalent chromium 86% and 89%,respectively,from the industrial effuents after 144 h.Cell free extracts of Bacillus sp.JDM-2-1 and S.capitis showed reduction of 83% and 70% at concentration of 10 μg Cr（Ⅵ）/mL,respectively.The presence of an induced protein having molecular weight around 25 kDa in the presence of chromium points out a possible role of this protein in chromium reduction.The bacterial isolates can be exploited for the bioremediation of hexavalent chromium containing wastes,since they seem to have a potential to reduce the toxic hexavalent form to its nontoxic trivalent form.展开更多
Forty-six candidate phenol/benzoate degrading-iron reducing bacteria were isolated from long term irrigated tropical paddy soils by enrichment procedures.Pure cultures and some prepared mixed cultures were examined fo...Forty-six candidate phenol/benzoate degrading-iron reducing bacteria were isolated from long term irrigated tropical paddy soils by enrichment procedures.Pure cultures and some prepared mixed cultures were examined for ferric oxide reduction and phenol/benzoate degradation.All the isolates were iron reducers,but only 56.5%could couple iron reduction to phenol and/or benzoate degradation,as evidenced by depletion of phenol and benzoate after one week incubation.Analysis of degradative capability using Biolog...展开更多
Optimized nitrogen(N)management can increase N-use efficiency in intercropping systems.Legume-nonlegume intercropping systems can reduce N input by exploiting biological N fixation by legumes.Measurement of N utilizat...Optimized nitrogen(N)management can increase N-use efficiency in intercropping systems.Legume-nonlegume intercropping systems can reduce N input by exploiting biological N fixation by legumes.Measurement of N utilization can help in dissecting the mechanisms underlying N uptake and utilization in legume-nonlegume intercropping systems.An experiment was performed with three planting patterns:monoculture maize(MM),monoculture soybean(SS),and maize-soybean relay intercropping(IMS),and three N application levels:zero N(NN),reduced N(RN),and conventional N(CN)to investigate crop N uptake and utilization characteristics.N recovery efficiency and 15N recovery rate of crops were higher under RN than under CN,and those under RN were higher under intercropping than under the corresponding monocultures.Compared with MM,IMS showed a lower soil N-dependent rate(SNDR)in 2012.However,the SNDR of MM rapidly declined from 86.8%in 2012 to 49.4%in 2014,whereas that of IMS declined slowly from 75.4%in 2012 to 69.4%in 2014.The interspecific N competition rate(NCRms)was higher under RN than under CN,and increased yearly.Soybean nodule dry weight and nitrogenase activities were respectively 34.2%and 12.5%higher under intercropping than in monoculture at the beginning seed stage.The amount(Ndfa)and ratio(%Ndfa)of soybean N2 fixation were significantly greater under IS than under SS.In conclusion,N fertilizer was more efficiently used under RN than under CN;in particular,the relay intercropping system promoted N fertilizer utilization in comparison with the corresponding monocultures.An intercropping system helps to maintain soil fertility because interspecific N competition promotes biological N fixation by soybean by reducing N input.Thus,a maize-soybean relay intercropping system with reduced N application is sustainable and environmentally friendly.展开更多
Delayed liver laceration following transjugular intrahepatic portosystemic shunt (TIPS) is a serious and likely underdiagnosed complication. It is however an important complication following TIPS, which remains one of...Delayed liver laceration following transjugular intrahepatic portosystemic shunt (TIPS) is a serious and likely underdiagnosed complication. It is however an important complication following TIPS, which remains one of the most technically challenging interventional procedures performed. In addition to laceration, a number of complications regarding bleeding and perforation are well described following TIPS procedures. We feel the adoption of techniques such as ours and that of other authors described in the literature using an ultrasoundguided percutaneous transhepatic approach with a small caliber needle provides a safer and less traumatic procedure and should reduce complications of bleeding and almost completely eliminate the risk of liver laceration. Our procedure was successfully performed under conscious sedation rather than general anaesthesia further reducing the overall procedural risk to the patient.展开更多
In this paper, a new pressure reducing valve （PRV） with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulatio...In this paper, a new pressure reducing valve （PRV） with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulation method was used to investigate the PRV internal flow field and to analyze the throttling effects of the orifice plate and the transform of thermal parameters as outlet pressure, outlet temperature, velocity, and superheat. A structure improvement method for the valve body and orifice plate is put forward to reduce energy loss. The governing equations for internal flow numerical simulation are composed of the continuity, momentum, energy and k-e transport equations, based on isotropic eddy viscosity theory. Different valve plug displacement models were built to describe the double throttling process. Our analysis shows that the steam pressure drops twice and the degree of superheat increases. There are also lots of eddies which clog the flow channel and disturb the steam flow in the valve cavity after the valve plug and the outlet cavity. After modifying the structure, the numerical results show a better performance of steam flow.展开更多
文摘BACKGROUND Ulcerative colitis(UC)is a chronic and debilitating inflammatory bowel disease.Cumulative evidence indicates that excess hydrogen peroxide,a potent neutrophilic chemotactic agent,produced by colonic epithelial cells has a causal role leading to infiltration of neutrophils into the colonic mucosa and subsequent development of UC.This evidence-based mechanism identifies hydrogen peroxide as a therapeutic target for reducing agents in the treatment of UC.CASE SUMMARY Presented is a 41-year-old female with a 26-year history of refractory UC.Having developed steroid dependence and never achieving complete remission on treatment by conventional and advanced therapies,she began treatment with oral R-dihydrolipoic acid(RDLA),a lipid-soluble reducing agent with intracellular site of action.Within a week,rectal bleeding ceased.She was asymptomatic for three years until a highly stressful experience,when she noticed blood in her stool.RDLA was discontinued,and she began treatment with oral sodium thiosulfate pentahydrate(STS),a reducing agent with extracellular site of action.After a week,rectal bleeding ceased,and she resumed oral RDLA and discontinued STS.To date,she remains asymptomatic with normal stool calprotectin while on RDLA.CONCLUSION STS and RDLA are reducing agents that serve as highly effective and safe therapy for the induction and maintenance of remission in UC,even in patients refractory or poorly controlled by conventional and advanced therapies.Should preliminary findings be validated by subsequent clinical trials,the use of reducing agents could potentially prevent thousands of colectomies and represent a paradigm shift in the treatment of UC.
基金the financial support of the National Natural Science Foundation of China(No.51971191)Scientific Research Project of Education Department of Hunan Province(Nos.22B0178,22C0075)+1 种基金Hunan Provincial Innovation Foundation for Postgraduate(No.CX20220558)the National Scholarship Foundation(No.202008430013)。
文摘The sulfate-reducing bacteria(SRB)corrosion of H70 brass,H80 brass and T2 copper was systematically studied using microstructure characterizations and electrochemical measurements.The results showed that H70 brass,H80 brass and T2 copper exhibited good corrosion resistance in the sterile environment,and the corrosion products were mainly metal oxides,such as Cu_(2)O,CuO and ZnO.The SRB metabolism sharply accelerated the corrosion process of three types of copper alloys,especially the T2 copper.In the inoculated environment,an additional mixture of Cu_(2)S,ZnS and CuSO_(4)existed in the corrosion products.Pitting corrosion was the main corrosion style for the H70 brass and H80 brass,while general corrosion and pitting corrosion simultaneously dominated the corrosion process of the T2 copper in this environment.The results provide a new insight to the microbiological corrosion of copper alloys.
基金financial support for the research and for the publication costs of the articlesupported by Santa Catarina State Research Support Foundation(FAPESC)National Council for Scientific and Technological Development(CNPq no 302903/2023-2).
文摘Cement production,while essential for global infrastructure,contributes significantly to carbon dioxide emissions,accounting for approximately 7%of total emissions.To mitigate these environmental impacts,flash calcination of kaolinitic clays has been investigated as a sustainable alternative.This technique involves the rapid heating of clays,enabling their use as supplementary cementitious materials.The primary objective of this study was to modify the color of calcined clay in various atmospheres(oxidizing,inert,and reducing)to achieve a grayish tone similar to commercial cement while preserving its reactive properties.The experimental procedure employed a tubular reactor with precise control of gas flows(atmospheric air,nitrogen,and a carbon monoxide–nitrogen mixture).Physicochemical characterization of the raw clay was conducted before calcination,with analyses repeated on the calcined clays following experimentation.Results indicated that clay calcined in an oxidizing atmosphere acquired a reddish hue,attributed to the oxidation of iron in hematite.The Clay exhibited a pinkish tone in an inert atmosphere,while calcination in a reducing atmosphere yielded the desired grayish color.Regarding pozzolanic activity,clays calcined in oxidizing and inert atmospheres displayed robust strength,ranging from 82%to 87%.Calcination in a reducing atmosphere resulted in slightly lower strength,around 74%,likely due to the clay’s chemical composition and the calcination process,which affects compound formation and material reactivity.
基金financial support provided by Lehigh University,the Advanced Technology for Large Structural Systems(ATLSS)Engineering Research Center,and the Department of Structural Engineering at the University of California,San Diegolarge research team led by Professor Robert B.Fleischman under the project“NEESR:Inertial Force-Limiting Floor Anchorage Systems for Seismic Resistant Building Structures”with the support of grants from the National Science Foundation,award no.CMMI-1135033in the George E.Brown,Jr.Network for Earthquake gineering En-Simulation Research(NEESR)program and award no.CMMI-0402490 for the George E.Brown,Jr.Network for Earthquake ing Engineer-Simulation(NEES)consortium operations.
文摘This study numerically investigates the seismic response of a nine-story self-centering concentrically braced frame building incorporating force-limiting connections between the floor system and the lateral force-resisting system.Nonlinear earthquake simulations are conducted under design basis earthquake ground motions,and the results are compared against a baseline model with rigid-elastic connections.The study discusses connection design considerations and evaluates the effectiveness of force-limiting connections in mitigating higher-mode effects.The findings show that force-limiting connections significantly reduce the magnitude and variability of floor accelerations,brace forces,and connection forces,while maintaining comparable story drifts.limiting Force-connections primarily reduce the contribution of higher-mode responses,while the controlled rocking base mechanism modifies the first-mode response.Overall,the reduced dispersion in structural response improves the reliability of seismic design and enhances resilience by minimizing damage to both structural components and acceleration-sensitive nonstructural elements.
基金supported financially by the National Natural Science Foundation of China(52202434)the National Natural Science Foundation of Ningbo(2023J275).
文摘Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy sector.Methanol plays an important role in the natural gas industry,typically serving as a solvent or hydrate inhibitor.Therefore,the accurate estimation of thermodynamic properties for methane/methanol binary is extremely important to optimise the operating parameter,maximise the dehydration effect,and reduce the cost.As the Helmholtz energy equation of state is expected to offer high accuracy in predicting the vapour-liquid equilibrium of methane/methanol binary,four reducing parameters were derived based on collected experimental data.Additionally,the sensitivities of various reducing parameter combinations were simultaneously investigated.The results demonstrated a strong agreement between predicted fractions and experimental data,with the UMADs(uncertainty-weighted mean absolute deviation)of 3.484 and 0.665 for liquid and vapour phases,respectively.Meanwhile,it is deemed“very likely”,“likely”,and“unlikely”to achieve acceptable prediction for 3-parameter optimisation,2-parameter optimisation and,1-parameter optimisation,respectively.
基金funded by the National Natural Science Foundation of China(NSFC,grant 81761128033)the Canadian Institutes of Health Research(CIHR,FRN 154986)through the Collaborative Health Program of the Global Alliance for Chronic Disease(GACD).
文摘Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an urgent priority,particularly in low-and middle-income countries(LMICs).This study aimed to evaluate the effectiveness of the Acceptance&Commitment to Empowerment:Linking Youths AND‘Xin’(Hearts)(ACE-LYNX)intervention in reducing stigma,improving psychological well-being,and enhancing the MHL and empowerment practices of university mental health providers in China.Methods:A total of 124 trained providers participated in this longitudinal study.Quantitative data were collected at baseline,immediately post-intervention,and three-month follow-up using the validated scale(CAMI,DASS-21)and weekly activity logs recording empowerment practices.Generalized estimating equations(GEEs)and qualitative content analysis were used for data analysis.Results:Quantitative analysis showed a significant reduction in stigma immediately postintervention,particularly in the Social Restriction subscale(β=1.35,p<0.001),though this effect diminished by the 3-month follow-up(β=1.80,p=0.001).Notably,a lasting reduction in the providers’stress levels was maintained.Activity logs showed the highest level of engagement at the individual level(51.4%),followed by group level(32.0%),organizational level(10.5%),and community level(6.1%).Qualitative analysis revealed three themes:Skill-based empowerment enhances professional efficacy,embedded interventions expand service boundaries,and organizational empowerment fosters sustainability.Conclusions:This dual-focus ACE-LYNX intervention effectively improved MHL and both attitudinal and functional competencies among providers.It provides a scalable framework for fostering sustainable and inclusive campus mental health ecosystems,with significant implication for enhance psychological services in resource-constrained educational settings.
基金the National Natural Science Foundation of China(Nos.21907080,22278330)Youth Innovative Team(No.xtr052022012)+3 种基金Fundamental Research Funds for the Central University(No.xzy012023010)from Xi’an Jiaotong Universitysupported by Natural Science Basic Research Program of Shaanxi(No.2023-JC-QN-0246)China/Shaanxi Postdoctoral Science Foundation(Nos.2023M732811,2023BSHEDZZ20)the University of Bath and the Open Research Fund of the School of Chemistry and Chemical Engineering,Henan Normal University(No.2020ZD01)for support。
文摘Redox dyshomeostasis is a critical factor in the initiation of numerous diseases,making the accurate evaluation of the redox status of the cellular environment an important aspect of physiological research.However,maintaining redox homeostasis relies on a complex and dynamic physiological system involving multiple substrate-enzyme interactions,so its accurately detection remains a challenge.With this research,we developed an activable fiuorescence switching platform by incorporating different conjugate acceptors to a fiuorophore using ester bonds and resulting in fiuorescence quenching due to donor-excited photo-induced electron transfer(d-Pe T),which was confirmed through density functional theory calculations.The reaction-based probe was deployed for recognizing all major intracellular reducing sulfur species(RSS),including H_(2)S,cysteine(Cys),homocysteine(Hcy),glutathione(GSH),and protein free thiols.The quenched fiuorescence was significantly recovered by RSS,through releasing the fiuorophore and diminishing the d-Pe T effect.Furthermore,the fiuorescent probe was used for the sensing and imaging RSS in living cells,demonstrating good cell-permeability,low cytotoxicity,and negative correlation with reactive oxygen species content,enabling the evaluating of global thiols redox state in Hep G2 cellular lines during ferroptosis processes.
文摘In the article“Silencing of the long non-coding RNA LINC00265 triggers autophagy and apoptosis in lung cancer by reducing protein stability of SIN3A oncogene”(Oncology Research.2024,Vol.32,No.7,pp.1185–1195.doi:10.32604/or.2023.030771,https://www.techscience.com/or/v32n7/57163),an inadvertent error occurred during the compilation of Fig.3H.This needed corrections to ensure the accuracy and integrity of the data presented.
文摘Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.
基金Supported by Daqing Scientific and Technological Project in Heilongjiang Province(SGG2007-054)Demonstration and Promotion Projects of Potato Comprehensive High Yield Cultivation Technologyin Western Regions of Heilongjiang Province(PC07B09)~~
文摘[Objective] The aim was to investigate the effects of plant growth regulators on contents of reducing sugar and starch in potato（Solanum tuberosum L.）.[Method]A potato cultivar named ＇Holand-212＇ with three treatments by spraying Diethyl aminoethyl hexanoate（DTA-6）,Uniconazole（S3307）and SOD mimics（SODM）were employed to compare differences of the contents of reducing sugar and starch in potato leaves,stolons and tubers in a field experiment.[Result]DTA-6 treatment could significantly reduce the contents of starch and reducing sugar in potato stolons in the period of 100-110 d after seeding,and it could also reduce the content of reducing sugar in tubers,but there is an opposite result in leaves in the same period,significantly.S3307 could extremely significantly increase the content of starch,and can promote the transfer of starch in stolons,in addition,it also could reduce the content of reducing sugar in tubers,and extremely significantly increase the content of starch in leaves at the 110 d after sowing.Moreover,there is a similar effect between SODM and S3307.[Conclusion]The research results are significant for understanding mechanisms of plant growth regulators and promoting application of plant growth regulator in potato.
文摘Anyplace where differences are found leaves room for stereotypes.Each of us hears or makes stereotypical comments every day,and although sometimes it is necessary to make stereotypes in foreign language teaching and learning,we should always be aware of the negative effects of stereotyping people from other cultures when we use them to interpret behavior.This paper defines stereotypes,discusses how they impede communication and then focuses on some ways to challenge and reduce stereotypes in cross-cultural communication.
基金Project(51373097)supported by The National Natural Science Foundation of China
文摘The effect of reducing agents and surfactants on controlling the silver nanoplates was studied. Two reducing agents, trisodium citrate dehydrate (TSC) and potassium tartrate, were used to reduce the AgNO3 solution. In this redox system, polyvinylpyrrolidone (PVP), sodium dodecyl sulfate (SDS) and arabic gum were served as surfactants. The results showed that reducing agents and surfactants both act as the capping agent adhering to the certain facets of silver seeds to block this surface to grow. The relative intensity of reducing agents also takes an active part in influencing the growth rate and direction of silver seeds. It was also found that halides can accelerate the speed of Ostwald ripening by adding Cl?, Br? and I?into the aqueous and have some effects on the morphology of the nanoplates.
基金supported by the Ministry of Higher Education, Malaysia [grant number FRG0416-TK-1/2015]UMSGreat funding from Universiti Malaysia Sabah [grant number GUG0052-TK2/2016]
文摘Drag reduction phenomenon in pipelines has received lots of attention during the past decades due to its potential engineering applications, especially in fluid transporting industries. Various methods to enhance drag reduction have been developed throughout the years and divided into two categories;non-additives method and additives method. Both categories have different types of methods, with different formulations and applications which will generally be discussed in this review. Among all the methods discussed, drag reduction using polymer additive is as one of the most enticing and desirable methods. It has been the subject of research in this field and has been studied extensively for quite some time. It is due to its ability to reduce drag up to 80% when added in minute concentrations. Reducing drag in the pipe will require less pumping power thus offering economic relieves to the industries. So, this paper will be focusing more on the use of polymer additives as drag reducing agent, the general formulations of the additives, major issues involving the use of drag reducing polymers, and the potential applications of it. However, despite the extensive works of drag reduction polymer, there are still no models that accurately explain the mechanism of drag reduction. More studies needed to be done to have a better understanding of the phenomenon. Therefore, future research areas and potential approaches are proposed for future work.
文摘The morphology and chemical compositions of surface and corrosion phases for two aluminum alloys(7075 and 2024 ) in the aqueous mediums containing sulfate reducing bacteria(SRB) were studied by the methods of scanning electron microscopy (SEM) and energy dispersive x ray analysis (EDXA). The results showed that serious pitting corrosion took place when aluminum alloys were exposed in the mediums containing SRB, whereas no pitting corrosion were found on the surfaces of aluminum alloys only exposed in blank mediums non containing SRB. It was demonstrated with EDXA that corrosion of aluminum alloys exposed in the solutions containing SRB, whereas the corrosion in the solution non containing microorganisms was attributed to the presence of chloride ions(Cl ).
文摘Cities ability reducing earthquake disasters is a complex system involving numerous factors, moreover the re-search on evaluating cities ability reducing earthquake disasters relates to multi-subject, such as earthquake sci-ence, social science, economical science and so on. In this paper, firstly, the conception of cities ability reducing earthquake disasters is presented, and the ability could be evaluated with three basic elements the possible seis-mic casualty and economic loss during the future earthquakes that are likely to occur in the city and its surround-ings and time required for recovery after earthquake; based upon these three basic elements, a framework, which consists of six main components, for evaluating citys ability reducing earthquake disasters is proposed; then the statistical relations between the index system and the ratio of seismic casualty, the ratio of economic loss and re-covery time are gained utilizing the cities prediction results of earthquake disasters which were made during the ninth five-year plan; at last, the method defining the comprehensive index of cities ability reducing earthquake disasters is presented. Thus the relatively comprehensive theory frame is set up. The frame can evaluate cities ability reducing earthquake disasters absolutely and quantitatively and consequently instruct the decision-making on reducing cities earthquake disasters loss.
文摘The present study was aimed to assess the ability of Bacillus sp.JDM-2-1 and Staphylococcus capitis to reduce hexavalent chromium into its trivalent form.Bacillus sp.JDM-2-1 could tolerate Cr（Ⅵ）（4800 μg/mL） and S.capitis could tolerate Cr（Ⅵ）（2800 μg/mL）.Both organisms were able to resist Cd^2＋（50 μg/mL）,Cu^2＋（200 μg/mL）,Pb^2＋（800 μg/mL）,Hg^2＋（50 μg/mL） and Ni2＋（4000 μg/mL）.S.capitis resisted Zn^2＋ at 700 μg/mL while Bacillus sp.JDM-2-1 only showed resistance up to 50 μg/mL.Bacillus sp.JDM-2-1 and S.capitis showed optimum growth at pH 6 and 7,respectively,while both bacteria showed optimum growth at 37°C.Bacillus sp.JDM-2-1 and S.capitis could reduce 85% and 81% of hexavalent chromium from the medium after 96 h and were also capable of reducing hexavalent chromium 86% and 89%,respectively,from the industrial effuents after 144 h.Cell free extracts of Bacillus sp.JDM-2-1 and S.capitis showed reduction of 83% and 70% at concentration of 10 μg Cr（Ⅵ）/mL,respectively.The presence of an induced protein having molecular weight around 25 kDa in the presence of chromium points out a possible role of this protein in chromium reduction.The bacterial isolates can be exploited for the bioremediation of hexavalent chromium containing wastes,since they seem to have a potential to reduce the toxic hexavalent form to its nontoxic trivalent form.
文摘Forty-six candidate phenol/benzoate degrading-iron reducing bacteria were isolated from long term irrigated tropical paddy soils by enrichment procedures.Pure cultures and some prepared mixed cultures were examined for ferric oxide reduction and phenol/benzoate degradation.All the isolates were iron reducers,but only 56.5%could couple iron reduction to phenol and/or benzoate degradation,as evidenced by depletion of phenol and benzoate after one week incubation.Analysis of degradative capability using Biolog...
基金supported by the National Natural Science Foundation of China(31671625,31271669)the National Key Research and Development Program of China(2016YFD0300202)
文摘Optimized nitrogen(N)management can increase N-use efficiency in intercropping systems.Legume-nonlegume intercropping systems can reduce N input by exploiting biological N fixation by legumes.Measurement of N utilization can help in dissecting the mechanisms underlying N uptake and utilization in legume-nonlegume intercropping systems.An experiment was performed with three planting patterns:monoculture maize(MM),monoculture soybean(SS),and maize-soybean relay intercropping(IMS),and three N application levels:zero N(NN),reduced N(RN),and conventional N(CN)to investigate crop N uptake and utilization characteristics.N recovery efficiency and 15N recovery rate of crops were higher under RN than under CN,and those under RN were higher under intercropping than under the corresponding monocultures.Compared with MM,IMS showed a lower soil N-dependent rate(SNDR)in 2012.However,the SNDR of MM rapidly declined from 86.8%in 2012 to 49.4%in 2014,whereas that of IMS declined slowly from 75.4%in 2012 to 69.4%in 2014.The interspecific N competition rate(NCRms)was higher under RN than under CN,and increased yearly.Soybean nodule dry weight and nitrogenase activities were respectively 34.2%and 12.5%higher under intercropping than in monoculture at the beginning seed stage.The amount(Ndfa)and ratio(%Ndfa)of soybean N2 fixation were significantly greater under IS than under SS.In conclusion,N fertilizer was more efficiently used under RN than under CN;in particular,the relay intercropping system promoted N fertilizer utilization in comparison with the corresponding monocultures.An intercropping system helps to maintain soil fertility because interspecific N competition promotes biological N fixation by soybean by reducing N input.Thus,a maize-soybean relay intercropping system with reduced N application is sustainable and environmentally friendly.
文摘Delayed liver laceration following transjugular intrahepatic portosystemic shunt (TIPS) is a serious and likely underdiagnosed complication. It is however an important complication following TIPS, which remains one of the most technically challenging interventional procedures performed. In addition to laceration, a number of complications regarding bleeding and perforation are well described following TIPS procedures. We feel the adoption of techniques such as ours and that of other authors described in the literature using an ultrasoundguided percutaneous transhepatic approach with a small caliber needle provides a safer and less traumatic procedure and should reduce complications of bleeding and almost completely eliminate the risk of liver laceration. Our procedure was successfully performed under conscious sedation rather than general anaesthesia further reducing the overall procedural risk to the patient.
基金Project (No. 2012C11018-1) supported by the Science and Technology Department of Zhejiang Province,China
文摘In this paper, a new pressure reducing valve （PRV） with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulation method was used to investigate the PRV internal flow field and to analyze the throttling effects of the orifice plate and the transform of thermal parameters as outlet pressure, outlet temperature, velocity, and superheat. A structure improvement method for the valve body and orifice plate is put forward to reduce energy loss. The governing equations for internal flow numerical simulation are composed of the continuity, momentum, energy and k-e transport equations, based on isotropic eddy viscosity theory. Different valve plug displacement models were built to describe the double throttling process. Our analysis shows that the steam pressure drops twice and the degree of superheat increases. There are also lots of eddies which clog the flow channel and disturb the steam flow in the valve cavity after the valve plug and the outlet cavity. After modifying the structure, the numerical results show a better performance of steam flow.
