The exploitation of organic-inorganic hybrid perovskites(OIHPs) as active layer materials for typical sandwich-structured resistive memories has attracted widespread interest due to the property of low power consumpti...The exploitation of organic-inorganic hybrid perovskites(OIHPs) as active layer materials for typical sandwich-structured resistive memories has attracted widespread interest due to the property of low power consumption and fast switching. However, the inherent thermal instability of perovskites limits the application of OIHPs-based resistive memories under extreme conditions, while the infiuence of thermal effects on their resistance change characteristics remains unclear. Herein, a novel 2D <100>-oriented high-temperature resistant OIHP [(BIZ-H)_(2)(PbBr_(4))]n(BIZ = benzimidazole) is prepared as an active layer material to fabricate FTO/[(BIZ-H)_(2)(PbBr_(4))]n/Ag resistive memory with excellent thermal reproducibility and stability up to 120℃. The increase in temperature leads to a decrease in the PbBr_(6) octahedral distortion in the crystal structure, an increase in hydrogen bonding between the(BIZ-H)+cation and the(PbBr_(4))_(n)^(2n-)layer, and a shortening of the spacing of the inorganic layers, which is found to result in the creation and predominance of thermally activated traps with increasing temperature. This work provides a new direction for the next generation of OIHPs-based resistive memories with high-temperature tolerance.展开更多
The high demands for load-carrying capability and structural efficiency of composite-metal bolted joints trigger in-depth investigations on failure mechanisms of the joints in hygrothermal environments.However,few stu...The high demands for load-carrying capability and structural efficiency of composite-metal bolted joints trigger in-depth investigations on failure mechanisms of the joints in hygrothermal environments.However,few studies have been presented to exhaustively reveal hygrothermal effects on the failure of CFRP-metal bolted joints,which differ from CFRP-CFRP or metal-metal bolted joints because of the remarkably different material properties of CFRPs and metals.In this paper,hygrothermal effects on tensile failures of single-lap and double-lap CFRP-aluminum bolted joints were experimentally and numerically investigated.A novel numerical model,in which a hygrothermal-included progressive damage model of composites was established and elastic-plastic models of metals were built,was proposed to predict the failures of the CFRP-metal bolted joints in hygrothermal environments and validated by corresponding experiments.Different failure mechanisms of single-lap and double-lap CFRP-aluminum bolted joints,under 23°C/Dry and 70°C/Wet conditions,were revealed,respectively.It follows that both the collapse failures of the single-lap and double-lap bolted joints were dominated by the bearing failure of the CFRP hole laminate in the two conditions,indicating that the hygrothermal environment did not change the macro failure modes of the joints.However,the hygrothermal environment considerably shortened the damage propagation processes and reduced the strength of the joints.Besides,the hygrothermal environment weakened the load-transfer capability of the single-lap joint more severely than the double-lap joint because it aggravated the secondary bending effects of the single-lap joint obviously.展开更多
Persistent free radicals(PFRs)in biochar have attracted wide attention due to their multifaceted roles in the environment.The regulation of PFRs in biochar is not only beneficial to broaden its application potential,b...Persistent free radicals(PFRs)in biochar have attracted wide attention due to their multifaceted roles in the environment.The regulation of PFRs in biochar is not only beneficial to broaden its application potential,but also eliminates its environmental risks.However,as a common biochar modification reagent,phosphoric acid(H_(3)PO_(4))has not been studied in the field of PFRs regulation.Herein,this study systematically investigated the effect of H_(3)PO_(4)on PFRs in biochar under various conditions.The results indicated that H_(3)PO_(4)promoted the formation of PFRs in biochar at low pyrolysis temperature(<500℃),owing to the positive effect of catalytic cross-linking on the degradation of biomass precursor.Yet,H_(3)PO_(4)reduced PFRs in biochar at high pyrolysis temperature(≥500℃),since the capture of H∙or HO∙by PO∙and the steric hindrance changed by H_(3)PO_(4),which caused the rearrangement and polycondensation of carbon structure.H_(3)PO_(4)also favored carbon-centered PFRs as the dominant type.The ingredients of biomass precursor,including cellulose,Fe,Ti,protein,etc.,contributed to different effects on PFRs under H_(3)PO_(4)modification.This study provided new insights into the roles of H_(3)PO_(4)on the formation and transformation of PFRs in biochar,coupled with regulation strategies in the practical application.展开更多
Lithium metal batteries(LMBs)have been regarded as one of the most promising alternatives in the post-lithium battery era due to their high energy density,which meets the needs of light-weight electronic devices and l...Lithium metal batteries(LMBs)have been regarded as one of the most promising alternatives in the post-lithium battery era due to their high energy density,which meets the needs of light-weight electronic devices and long-range electric vehicles.However,technical barriers such as dendrite growth and poor Li plating/stripping reversibility severely hinder the practical application of LMBs.However,lithium nitrate(LiNO_(3))is found to be able to stabilize the Li/electrolyte interface and has been used to address the above challenges.To date,considerable research efforts have been devoted toward understanding the roles of LiNO_(3) in regulating the surface properties of Li anodes and toward the development of many effective strategies.These research efforts are partially mentioned in some articles on LMBs and yet have not been reviewed systematically.To fill this gap,we discuss the recent advances in fundamental and technological research on LiNO_(3) and its derivatives for improving the performances of LMBs,particularly for Li-sulfur(S),Li-oxygen(O),and Li-Li-containing transition-metal oxide(LTMO)batteries,as well as LiNO_(3)-containing recipes for precursors in battery materials and interphase fabrication.This review pays attention to the effects of LiNO_(3) in lithium-based batteries,aiming to provide scientific guidance for the optimization of electrode/electrolyte interfaces and enrich the design of advanced LMBs.展开更多
Under the pressures of both the de＇crease of high-grade high quality iron ore resources and the increase of raw material costs, the iron and steel enter＇prises in China turn to adopt iron ores which contain special ...Under the pressures of both the de＇crease of high-grade high quality iron ore resources and the increase of raw material costs, the iron and steel enter＇prises in China turn to adopt iron ores which contain special elements such as nickel, manganese, etc. in the sintering blend. Anaiytica｜ reagents were used for sintering experiments, and the sinters were analyzed with X-ray diffraction, s6ailning electron microscopy and mineralogical microscopy to study the effect of nickel on the silico ferrite of calcium and aluminum （SF（＇A） bonding phase formation during sinte- ring. The results indicated that SFCA was divided into nickel containing and nickel-free areas due to the presence of nickel. The increasing content of nickel would greatly reduce the content of SFCA and promote the formation of calcium aluminum silicate. A great deal of Fe2 Oa participated in the crystal transition to Fe3 O3 , reducing the a mount of Fe2O2 involved in the formation of calcium ferrite. When the blending ratio of NiO, which is used to provide the nickel in the sintering process, is less than 3 % , the calcium ferrite is in substantially interleaving cot rosion with hematite and magnetite. Both the porosity and silicate glass phase content are low, which contributes to the sintering production.展开更多
Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer, the biological effect and mechanism of material-organism interaction become more important. Since most of animal tes...Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer, the biological effect and mechanism of material-organism interaction become more important. Since most of animal tests and cellular experiments stay on the phenomenon description instead of mechanism interpretation, the development of proteomics technologies provides a golden opportunity to uncover the molecular interaction mechanism between biomaterial-organism on whole scale. This review summarizes current application of proteomics in biological effect and mechanism study of biomaterials, and discusses the development and challenges for future studies.展开更多
The structure of the solid solution treated and deformed Fe-25Mn-(0-3.11)Al-0.15C alloys was examined by means of metallograph and X-ray diffraction, which has confirmed that Al restrains the γ→ε transformation in ...The structure of the solid solution treated and deformed Fe-25Mn-(0-3.11)Al-0.15C alloys was examined by means of metallograph and X-ray diffraction, which has confirmed that Al restrains the γ→ε transformation in the Fe-Mn alloys. The mechanism on the restraining effect of Al has been discussed on the basis of the efFect of Al upon the stacking fault energy in the Fe-Mn alloys.Aluminium increases thermodynamically the stability of the Fe-Mn austenite and the driving force limit necessitated to be overcome for the γ→ε transformation, because the thermodynamicalcalculation indicates that Al increases the stacking fault energy in the Fe-Mn alloys at 300 K.Al will decrease the number and the size for the ε-martensite nucleus according to the stacking fault mechanism of the ε-martensite nucleation展开更多
This study aims to observe the protective effects of ginsenoside Rbl on liver and lung in rats with septic shock and reveal its mechanism. Rats were randomly divided into three groups： sham, cecal ligation and punctu...This study aims to observe the protective effects of ginsenoside Rbl on liver and lung in rats with septic shock and reveal its mechanism. Rats were randomly divided into three groups： sham, cecal ligation and puncture （CLP）, and CLP with ginsenoside Rb1. Then, the survival rate, arterial blood pressure, TLR4 mRNA, and TNF-α levels were determined. The liver and lung tissues were stained with hematoxylin-eosin （HE）. The overall survival rate of the Rb1 group was significantly higher than that of the CLP group. Mean arterial blood pressure went down in both the CLP and Rb1 groups after CLP, and there was a significant difference both in the sham and Rb1 groups when compared with the CLP group. The Rb1 treatment group had markedly lower TLR4 mRNA expression and TNF-a levels than the CLP group. In the CLP group, pathology showed swelling, degeneration, necrosis, and neutrophii infiltration in the liver and alveolar epithelial cells. However, in the Rb1 group, there was mild degeneration and slight neutrophil infiltration, but no obvious necrosis. Rb1 may improve the survival rate, ameliorate arterial blood pressure, and protect the liver and lung in septic shock rats by downregulating the expression of TLR4 mRNA and inhibiting the production of TNF-α.展开更多
Obesity has become one of the most prevalent health issues of our time. According to a 2012 WHO report, around 3.4 million adults die each year as a result of being overweight or obese. Humans are in fact superorganis...Obesity has become one of the most prevalent health issues of our time. According to a 2012 WHO report, around 3.4 million adults die each year as a result of being overweight or obese. Humans are in fact superorganisms composed of both human and microbial cells with 2 sets of genes, those encoded in our own genome and those encoded in our microbiota. All these cells and genes have the potential to influence our health.展开更多
In China, it is widely believed that teacher feedback plays a crucial role in EFL writing course, exerting a great impact on the improvement of Chinese EFL students＇ writing abilities so that teachers have been requi...In China, it is widely believed that teacher feedback plays a crucial role in EFL writing course, exerting a great impact on the improvement of Chinese EFL students＇ writing abilities so that teachers have been required to deliver feedback on students＇ writings. Teachers, consequently, spare no pains to give feedback, expecting their students would make progress in their writing, but it seems that things go contrary to their wishes. Although there are various complicated factors contributing to the situation, one of the important factors lies in the teachers, a number of whom do not grasp a systematic and effective mechanism of delivering feedback on EFL student writing. Much importance has been attached to Chinese EFL student writing, however, rare attention has been paid to conducting research on concrete ways of delivering feedback on Chinese EFL student writing in China. Therefore, this paper serves to fill the gap, mainly devoting itself to exploring concrete methods of delivering teacher feedback on EFL student writing.展开更多
The effects of mono-valent cations, Li^+, K^+, Rb^+, Cs^+ and NH_4^+, on ^(23)Na NMR were investigated. It was found that the chemical shifts for Na^+ signal shifted downfield with the increase in the relative amounts...The effects of mono-valent cations, Li^+, K^+, Rb^+, Cs^+ and NH_4^+, on ^(23)Na NMR were investigated. It was found that the chemical shifts for Na^+ signal shifted downfield with the increase in the relative amounts of monovalent cations. It was suggested that mono-valent cations had competition coordination with Na^+ for Dy(PPP)_2^(7-).展开更多
Degradation reaction of doxycycline or methacycline was carried out in KOH solution and intense fluorescence was obtained.A degradation mechanism of doxycycline or methacycline was suggested.
Objective: To investigate the effect and the mechanism of Shenfu injection (SFI, ) on the resuscitation from general anesthesia . Methods: Forty patients who received selective abdominal surgery with general anesthesi...Objective: To investigate the effect and the mechanism of Shenfu injection (SFI, ) on the resuscitation from general anesthesia . Methods: Forty patients who received selective abdominal surgery with general anesthesia for 3-4 hrs and ASA grade Ⅰ-Ⅱ were divided into two groups, the trial group and the control group, 20 patients in each group. After being sent into the postanesthesia care unit (PACU), the trial group was treated with intravenous dripping of SFI 1.0 ml/kg and the control group was treated with intravenous dripping of equal volume of normal saline. All patients were observed in double blindly manner, the self ventilation recovery time, extubation time, the time of leaving PACU and their Glasgow coma scale (GCS) were recorded and compared. 2 ml of peripheral venous blood were taken to determine the plasma β-endorphin (β-EP) content at the time points of before (T1), 5min (T2), 15min (T3) and 30 min (T4) after dripping. Results: The self ventilation recovery time, extubation time and time of leaving PACU in the trial group were all shorter than those in the control group (P<0 01), the GCS in the trial group was better than that in the control group (P<0 01). The plasma content of β-EP raised gradually along the recovering of patients consciousness, as compared with the content before dripping (T1), it showed insignificant difference at time point T2 but significant difference at T3 and T4, comparison at the corres ponding time point showed that the content at T1 and T2 were similar in the two groups (P>0 05), but at T3 and T4, the content was higher in the trial group than that in the control group respectively (P<0 01). There was insignificant difference between T1 and before treatment ( P>0 05), but significant difference was found when compared T3, T4 and before treatment (P<0 01).Conclusion: SFI could accelerate the resuscitation after general anesthesia, the mechanism may be related with its action in raising plasma β-EP level.展开更多
The effects of riboflavin deficiency and simultaneously nitrosodimethylamine (NDMA) given by gastric intubation on the hepatic glutathione (GSH) content were examined in rats. On different days of the experiment, hepa...The effects of riboflavin deficiency and simultaneously nitrosodimethylamine (NDMA) given by gastric intubation on the hepatic glutathione (GSH) content were examined in rats. On different days of the experiment, hepatic GSH content of the riboflavin deficient rats decreased to 55-61% of the control rats. When NDMA was given 6 mg kg by gastric intubation to riboflavin deficient rats, hepatic GSH content decreased markedly to 39-43% of the control rats. After supplying riboflavin, hepatie GSH content of the deficient rats recovered to the level of the control rats. These results suggest that alterations of rat hepatic GSH content during riboflavin deficiency may imply as one of the promoting effects of riboflavin deficiency on the carcinogenesis of nitrosamines.展开更多
The coating and deposition process with excellent anti wear and suitable for industrial application were developed, and the optimum bath composition and process were obtained by studying the influence of the bath comp...The coating and deposition process with excellent anti wear and suitable for industrial application were developed, and the optimum bath composition and process were obtained by studying the influence of the bath composition, temperature and pH value on the deposition rate and the plating solution stability. Moreover, the tribological properties of nano-Cu lubricating additives and electroless deposited Ni-W-P coating as well as their synergistic effect are researched using ring-block abrasion testing machine and energy dispersive spectrometer. Research results show that Ni-W-P alloy coating and nano-Cu lubricating additive have excellent synergistic effect, e g, the wear resistance of Ni-W-P alloy coating （with heat treatment and the oil with nano-Cu additives） has increased hundreds times than 45 steel as the metal substrate with the basic oil, and zero wear is achieved, which breaks through the bottleneck of previous separate research of the above-mentioned two aspects.展开更多
By using a nine-layer global spectral model involving fuller parameterization of physical processes, with a rhomboidal truncation at wavenumber 15, experiments are performed in terms of two numerical schemes, one with...By using a nine-layer global spectral model involving fuller parameterization of physical processes, with a rhomboidal truncation at wavenumber 15, experiments are performed in terms of two numerical schemes, one with long-term mean coverage of Arctic ice (Exp.1), the other without the ice (Exp.2). Results indicate that the Arctic region is a heat source in Exp.2 relative to the case in Exp.1. Under the influence of the polar heat source simulated, there still exist stationary wavetrains that produce WA-EUP and weak PNA patterns in Northern winter. That either the Arctic or the tropical heat source can cause identical climatic effects is due to the fact that the anomaly of the Arctic ice cover will directly induce a south-propagating wavetrain, and bring about the redistribution of the tropical heat source / sink. The redistribution is responsible for new wavetrains that will exert impact on the global climate. The simulation results bear out further that the polar region in Exp.2 as a heat source, can produce, by local forcing, a pair of positive and negative difference centers, which circle the Arctic moving eastwards. Observed in the Northern Hemisphere extratropics is a 40-50 day oscillation in relation to the moving pair, both having the same period.展开更多
This paper discusses the novelty search report on the efficacy and mechanism of Gukangling liquid, and analyzes the project basis and research content of Gukangling liquid project. Research objectives and novelty sear...This paper discusses the novelty search report on the efficacy and mechanism of Gukangling liquid, and analyzes the project basis and research content of Gukangling liquid project. Research objectives and novelty search conclusions. We have developed and produced a valuable drug for patients, and provided experimental basis for future clinical application of Gukangling Liquid.展开更多
Objective To investigate the effect and mechanism of adrenomedullin ( AM ) on apoptosis of renal tubular epithelial cell in rats induced by renal ischemia reperfusion injury. Methods Thirty-two Wistar rats were random...Objective To investigate the effect and mechanism of adrenomedullin ( AM ) on apoptosis of renal tubular epithelial cell in rats induced by renal ischemia reperfusion injury. Methods Thirty-two Wistar rats were randomly divided into 4 groups: control group,IRI group, empty plasmid group and AM group. One week after re-展开更多
基金financially supported by the Ph.D. start-up funds of Jiangxi Science and Technology Normal University (Nos. 2023BSQD11, 2023BSQD13)Jiangxi Province Key Laboratory of Organic Functional Molecules (No. 2024SSY05141)。
文摘The exploitation of organic-inorganic hybrid perovskites(OIHPs) as active layer materials for typical sandwich-structured resistive memories has attracted widespread interest due to the property of low power consumption and fast switching. However, the inherent thermal instability of perovskites limits the application of OIHPs-based resistive memories under extreme conditions, while the infiuence of thermal effects on their resistance change characteristics remains unclear. Herein, a novel 2D <100>-oriented high-temperature resistant OIHP [(BIZ-H)_(2)(PbBr_(4))]n(BIZ = benzimidazole) is prepared as an active layer material to fabricate FTO/[(BIZ-H)_(2)(PbBr_(4))]n/Ag resistive memory with excellent thermal reproducibility and stability up to 120℃. The increase in temperature leads to a decrease in the PbBr_(6) octahedral distortion in the crystal structure, an increase in hydrogen bonding between the(BIZ-H)+cation and the(PbBr_(4))_(n)^(2n-)layer, and a shortening of the spacing of the inorganic layers, which is found to result in the creation and predominance of thermally activated traps with increasing temperature. This work provides a new direction for the next generation of OIHPs-based resistive memories with high-temperature tolerance.
基金supported by the National Science Foundation of China(11772028,11872131,11702012,U1864208,11572058 and 11372020)the Academic Excellence Foundation of BUAA for PhD Students.
文摘The high demands for load-carrying capability and structural efficiency of composite-metal bolted joints trigger in-depth investigations on failure mechanisms of the joints in hygrothermal environments.However,few studies have been presented to exhaustively reveal hygrothermal effects on the failure of CFRP-metal bolted joints,which differ from CFRP-CFRP or metal-metal bolted joints because of the remarkably different material properties of CFRPs and metals.In this paper,hygrothermal effects on tensile failures of single-lap and double-lap CFRP-aluminum bolted joints were experimentally and numerically investigated.A novel numerical model,in which a hygrothermal-included progressive damage model of composites was established and elastic-plastic models of metals were built,was proposed to predict the failures of the CFRP-metal bolted joints in hygrothermal environments and validated by corresponding experiments.Different failure mechanisms of single-lap and double-lap CFRP-aluminum bolted joints,under 23°C/Dry and 70°C/Wet conditions,were revealed,respectively.It follows that both the collapse failures of the single-lap and double-lap bolted joints were dominated by the bearing failure of the CFRP hole laminate in the two conditions,indicating that the hygrothermal environment did not change the macro failure modes of the joints.However,the hygrothermal environment considerably shortened the damage propagation processes and reduced the strength of the joints.Besides,the hygrothermal environment weakened the load-transfer capability of the single-lap joint more severely than the double-lap joint because it aggravated the secondary bending effects of the single-lap joint obviously.
基金supported by[National Natural Science Foundation of China](Grant numbers[52270059])[National Key Research and Development Program of China](Grant numbers[2020YFC1807800])[Natural Science Foundation of Liaoning Province of China](Grant numbers[2023-MS-095]).
文摘Persistent free radicals(PFRs)in biochar have attracted wide attention due to their multifaceted roles in the environment.The regulation of PFRs in biochar is not only beneficial to broaden its application potential,but also eliminates its environmental risks.However,as a common biochar modification reagent,phosphoric acid(H_(3)PO_(4))has not been studied in the field of PFRs regulation.Herein,this study systematically investigated the effect of H_(3)PO_(4)on PFRs in biochar under various conditions.The results indicated that H_(3)PO_(4)promoted the formation of PFRs in biochar at low pyrolysis temperature(<500℃),owing to the positive effect of catalytic cross-linking on the degradation of biomass precursor.Yet,H_(3)PO_(4)reduced PFRs in biochar at high pyrolysis temperature(≥500℃),since the capture of H∙or HO∙by PO∙and the steric hindrance changed by H_(3)PO_(4),which caused the rearrangement and polycondensation of carbon structure.H_(3)PO_(4)also favored carbon-centered PFRs as the dominant type.The ingredients of biomass precursor,including cellulose,Fe,Ti,protein,etc.,contributed to different effects on PFRs under H_(3)PO_(4)modification.This study provided new insights into the roles of H_(3)PO_(4)on the formation and transformation of PFRs in biochar,coupled with regulation strategies in the practical application.
基金supported by the Yunnan Fundamental Research Projects(Grant Nos.202401AU070163 and 202501AT070298)the Yunnan Engineering Research Center Innovation Ability Construction and Enhancement Projects(Grant No.2023-XMDJ-00617107)+5 种基金the University Service Key Industry Project of Yunnan Province(Grant No.FWCY-ZD2024005)the Expert Workstation Support Project of Yunnan Province(Grant No.202405AF140069)the Scientific Research Foundation of Kunming University of Science and Technology(Grant No.20220122)the Analysis and Test Foundation of Kunming University of Science and Technology(Grant No.2023T20220122)the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN02057)the Ordos City Strategic Pioneering Science and Technology Special Program for New Energy(Grant No.DC2400003365).
文摘Lithium metal batteries(LMBs)have been regarded as one of the most promising alternatives in the post-lithium battery era due to their high energy density,which meets the needs of light-weight electronic devices and long-range electric vehicles.However,technical barriers such as dendrite growth and poor Li plating/stripping reversibility severely hinder the practical application of LMBs.However,lithium nitrate(LiNO_(3))is found to be able to stabilize the Li/electrolyte interface and has been used to address the above challenges.To date,considerable research efforts have been devoted toward understanding the roles of LiNO_(3) in regulating the surface properties of Li anodes and toward the development of many effective strategies.These research efforts are partially mentioned in some articles on LMBs and yet have not been reviewed systematically.To fill this gap,we discuss the recent advances in fundamental and technological research on LiNO_(3) and its derivatives for improving the performances of LMBs,particularly for Li-sulfur(S),Li-oxygen(O),and Li-Li-containing transition-metal oxide(LTMO)batteries,as well as LiNO_(3)-containing recipes for precursors in battery materials and interphase fabrication.This review pays attention to the effects of LiNO_(3) in lithium-based batteries,aiming to provide scientific guidance for the optimization of electrode/electrolyte interfaces and enrich the design of advanced LMBs.
基金Sponsored by National Natural Science Foundation of China(51174023)
文摘Under the pressures of both the de＇crease of high-grade high quality iron ore resources and the increase of raw material costs, the iron and steel enter＇prises in China turn to adopt iron ores which contain special elements such as nickel, manganese, etc. in the sintering blend. Anaiytica｜ reagents were used for sintering experiments, and the sinters were analyzed with X-ray diffraction, s6ailning electron microscopy and mineralogical microscopy to study the effect of nickel on the silico ferrite of calcium and aluminum （SF（＇A） bonding phase formation during sinte- ring. The results indicated that SFCA was divided into nickel containing and nickel-free areas due to the presence of nickel. The increasing content of nickel would greatly reduce the content of SFCA and promote the formation of calcium aluminum silicate. A great deal of Fe2 Oa participated in the crystal transition to Fe3 O3 , reducing the a mount of Fe2O2 involved in the formation of calcium ferrite. When the blending ratio of NiO, which is used to provide the nickel in the sintering process, is less than 3 % , the calcium ferrite is in substantially interleaving cot rosion with hematite and magnetite. Both the porosity and silicate glass phase content are low, which contributes to the sintering production.
基金support of Natural Science Foundation of Guangdong Province, China (Nos. 2016A030310245 and 2016A030310244)China Postdoctoral Science Foundation (No. 2016M591017)Key Projects in the National Science &Technology Pillar program during the thirteenth Five-year Plan Period (No. 2016YFC1102800)
文摘Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer, the biological effect and mechanism of material-organism interaction become more important. Since most of animal tests and cellular experiments stay on the phenomenon description instead of mechanism interpretation, the development of proteomics technologies provides a golden opportunity to uncover the molecular interaction mechanism between biomaterial-organism on whole scale. This review summarizes current application of proteomics in biological effect and mechanism study of biomaterials, and discusses the development and challenges for future studies.
文摘The structure of the solid solution treated and deformed Fe-25Mn-(0-3.11)Al-0.15C alloys was examined by means of metallograph and X-ray diffraction, which has confirmed that Al restrains the γ→ε transformation in the Fe-Mn alloys. The mechanism on the restraining effect of Al has been discussed on the basis of the efFect of Al upon the stacking fault energy in the Fe-Mn alloys.Aluminium increases thermodynamically the stability of the Fe-Mn austenite and the driving force limit necessitated to be overcome for the γ→ε transformation, because the thermodynamicalcalculation indicates that Al increases the stacking fault energy in the Fe-Mn alloys at 300 K.Al will decrease the number and the size for the ε-martensite nucleus according to the stacking fault mechanism of the ε-martensite nucleation
基金supported by the Major Invite Tender Project of Health Department of Jiangxi Province(No.20104005)the Major Project of the Department of Education of Jiangxi Province(No.GJJ12003)the 13th’Challenge Cup’of Extracurricular academic and scientific works of Nanchang University
文摘This study aims to observe the protective effects of ginsenoside Rbl on liver and lung in rats with septic shock and reveal its mechanism. Rats were randomly divided into three groups： sham, cecal ligation and puncture （CLP）, and CLP with ginsenoside Rb1. Then, the survival rate, arterial blood pressure, TLR4 mRNA, and TNF-α levels were determined. The liver and lung tissues were stained with hematoxylin-eosin （HE）. The overall survival rate of the Rb1 group was significantly higher than that of the CLP group. Mean arterial blood pressure went down in both the CLP and Rb1 groups after CLP, and there was a significant difference both in the sham and Rb1 groups when compared with the CLP group. The Rb1 treatment group had markedly lower TLR4 mRNA expression and TNF-a levels than the CLP group. In the CLP group, pathology showed swelling, degeneration, necrosis, and neutrophii infiltration in the liver and alveolar epithelial cells. However, in the Rb1 group, there was mild degeneration and slight neutrophil infiltration, but no obvious necrosis. Rb1 may improve the survival rate, ameliorate arterial blood pressure, and protect the liver and lung in septic shock rats by downregulating the expression of TLR4 mRNA and inhibiting the production of TNF-α.
基金supported by the National Natural Science Foundation major international(regional)joint research project(81220108006)Young Scientists Fund of National Natural Science Foundation(81200292)+3 种基金‘Chen Guang’project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation(13CG11)Shanghai Rising-Star Program(13QA1402900)Hong Kong Scholars Program(XJ2013035)Doctoral Fund of Ministry of Education of China(137000)
文摘Obesity has become one of the most prevalent health issues of our time. According to a 2012 WHO report, around 3.4 million adults die each year as a result of being overweight or obese. Humans are in fact superorganisms composed of both human and microbial cells with 2 sets of genes, those encoded in our own genome and those encoded in our microbiota. All these cells and genes have the potential to influence our health.
文摘In China, it is widely believed that teacher feedback plays a crucial role in EFL writing course, exerting a great impact on the improvement of Chinese EFL students＇ writing abilities so that teachers have been required to deliver feedback on students＇ writings. Teachers, consequently, spare no pains to give feedback, expecting their students would make progress in their writing, but it seems that things go contrary to their wishes. Although there are various complicated factors contributing to the situation, one of the important factors lies in the teachers, a number of whom do not grasp a systematic and effective mechanism of delivering feedback on EFL student writing. Much importance has been attached to Chinese EFL student writing, however, rare attention has been paid to conducting research on concrete ways of delivering feedback on Chinese EFL student writing in China. Therefore, this paper serves to fill the gap, mainly devoting itself to exploring concrete methods of delivering teacher feedback on EFL student writing.
文摘The effects of mono-valent cations, Li^+, K^+, Rb^+, Cs^+ and NH_4^+, on ^(23)Na NMR were investigated. It was found that the chemical shifts for Na^+ signal shifted downfield with the increase in the relative amounts of monovalent cations. It was suggested that mono-valent cations had competition coordination with Na^+ for Dy(PPP)_2^(7-).
文摘Degradation reaction of doxycycline or methacycline was carried out in KOH solution and intense fluorescence was obtained.A degradation mechanism of doxycycline or methacycline was suggested.
文摘Objective: To investigate the effect and the mechanism of Shenfu injection (SFI, ) on the resuscitation from general anesthesia . Methods: Forty patients who received selective abdominal surgery with general anesthesia for 3-4 hrs and ASA grade Ⅰ-Ⅱ were divided into two groups, the trial group and the control group, 20 patients in each group. After being sent into the postanesthesia care unit (PACU), the trial group was treated with intravenous dripping of SFI 1.0 ml/kg and the control group was treated with intravenous dripping of equal volume of normal saline. All patients were observed in double blindly manner, the self ventilation recovery time, extubation time, the time of leaving PACU and their Glasgow coma scale (GCS) were recorded and compared. 2 ml of peripheral venous blood were taken to determine the plasma β-endorphin (β-EP) content at the time points of before (T1), 5min (T2), 15min (T3) and 30 min (T4) after dripping. Results: The self ventilation recovery time, extubation time and time of leaving PACU in the trial group were all shorter than those in the control group (P<0 01), the GCS in the trial group was better than that in the control group (P<0 01). The plasma content of β-EP raised gradually along the recovering of patients consciousness, as compared with the content before dripping (T1), it showed insignificant difference at time point T2 but significant difference at T3 and T4, comparison at the corres ponding time point showed that the content at T1 and T2 were similar in the two groups (P>0 05), but at T3 and T4, the content was higher in the trial group than that in the control group respectively (P<0 01). There was insignificant difference between T1 and before treatment ( P>0 05), but significant difference was found when compared T3, T4 and before treatment (P<0 01).Conclusion: SFI could accelerate the resuscitation after general anesthesia, the mechanism may be related with its action in raising plasma β-EP level.
文摘The effects of riboflavin deficiency and simultaneously nitrosodimethylamine (NDMA) given by gastric intubation on the hepatic glutathione (GSH) content were examined in rats. On different days of the experiment, hepatic GSH content of the riboflavin deficient rats decreased to 55-61% of the control rats. When NDMA was given 6 mg kg by gastric intubation to riboflavin deficient rats, hepatic GSH content decreased markedly to 39-43% of the control rats. After supplying riboflavin, hepatie GSH content of the deficient rats recovered to the level of the control rats. These results suggest that alterations of rat hepatic GSH content during riboflavin deficiency may imply as one of the promoting effects of riboflavin deficiency on the carcinogenesis of nitrosamines.
文摘The coating and deposition process with excellent anti wear and suitable for industrial application were developed, and the optimum bath composition and process were obtained by studying the influence of the bath composition, temperature and pH value on the deposition rate and the plating solution stability. Moreover, the tribological properties of nano-Cu lubricating additives and electroless deposited Ni-W-P coating as well as their synergistic effect are researched using ring-block abrasion testing machine and energy dispersive spectrometer. Research results show that Ni-W-P alloy coating and nano-Cu lubricating additive have excellent synergistic effect, e g, the wear resistance of Ni-W-P alloy coating （with heat treatment and the oil with nano-Cu additives） has increased hundreds times than 45 steel as the metal substrate with the basic oil, and zero wear is achieved, which breaks through the bottleneck of previous separate research of the above-mentioned two aspects.
文摘By using a nine-layer global spectral model involving fuller parameterization of physical processes, with a rhomboidal truncation at wavenumber 15, experiments are performed in terms of two numerical schemes, one with long-term mean coverage of Arctic ice (Exp.1), the other without the ice (Exp.2). Results indicate that the Arctic region is a heat source in Exp.2 relative to the case in Exp.1. Under the influence of the polar heat source simulated, there still exist stationary wavetrains that produce WA-EUP and weak PNA patterns in Northern winter. That either the Arctic or the tropical heat source can cause identical climatic effects is due to the fact that the anomaly of the Arctic ice cover will directly induce a south-propagating wavetrain, and bring about the redistribution of the tropical heat source / sink. The redistribution is responsible for new wavetrains that will exert impact on the global climate. The simulation results bear out further that the polar region in Exp.2 as a heat source, can produce, by local forcing, a pair of positive and negative difference centers, which circle the Arctic moving eastwards. Observed in the Northern Hemisphere extratropics is a 40-50 day oscillation in relation to the moving pair, both having the same period.
文摘This paper discusses the novelty search report on the efficacy and mechanism of Gukangling liquid, and analyzes the project basis and research content of Gukangling liquid project. Research objectives and novelty search conclusions. We have developed and produced a valuable drug for patients, and provided experimental basis for future clinical application of Gukangling Liquid.
文摘Objective To investigate the effect and mechanism of adrenomedullin ( AM ) on apoptosis of renal tubular epithelial cell in rats induced by renal ischemia reperfusion injury. Methods Thirty-two Wistar rats were randomly divided into 4 groups: control group,IRI group, empty plasmid group and AM group. One week after re-
