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CLINICAL RESEARCH OF JIAJI(夹脊EX-B2) IN TREATMENT OF SPASTIC CEREBRAL PALSY WITH ACUPUNCTURE 被引量:2
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作者 周君 刘红英 +2 位作者 邓晖 张翠莲 陈晓红 《World Journal of Acupuncture-Moxibustion》 2007年第4期22-26,共5页
Objective To observe the clinical therapeutic effects of Jiájǐ(夹脊EX-B2) on spastic cerebral palsy (SOP) with acupuncture.Methods 62 cases of SOP were randomized into two groups,named treat- ment group with... Objective To observe the clinical therapeutic effects of Jiájǐ(夹脊EX-B2) on spastic cerebral palsy (SOP) with acupuncture.Methods 62 cases of SOP were randomized into two groups,named treat- ment group with acupuncture on Jiájǐ(夹脊EX-B2),and control group with sham-acupuncture.The treatment was applied once a day,10 times made a course,totally 6 courses were required.Modified Ashworth scale and FIM grade were used to observe and assess the results of treatment.Results The total effective rate was 84.4 % in treatment group and was 63.3 % in control group,indicating significant difference (P〈0.01). Conclusion Acupuncture on Jiájǐ(夹脊EX-B2) achieves good clinical therapeutic effects on SCP. 展开更多
关键词 Cerebral palsy Jiájǐ(夹脊ex-b2 ACUPUNCTURE
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Electroacupuncture at jiājǐ(夹脊 EX-B2) for lumbar intervertebral disc herniation:A randomized controlled trial 被引量:10
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作者 Ping SHAO Zhen DU +4 位作者 Zhiping XIN Xiao ZHENG Minlei QIU Zheng ZHU Xuming YANG 《World Journal of Acupuncture-Moxibustion》 CSCD 2018年第3期167-173,I0003,共8页
Objective: To compare the effect differences of electroacupuncture(EA) at Jiajǐ(夹脊 EX-B2) and conventional acupoints for lumbar intervertebral disc herniation(LIDH) and the factors influenced the effect duri... Objective: To compare the effect differences of electroacupuncture(EA) at Jiajǐ(夹脊 EX-B2) and conventional acupoints for lumbar intervertebral disc herniation(LIDH) and the factors influenced the effect during the way of data mining.Methods: A total of 160 patients of LIDH were randomly assigned into the EX-B2 group and the conventional acupoints group, 80 cases in each one. The patients in the EX-B2 group received EA at the symmetrical 2 acupoints of the bilateral EX-B2 on the lesion part. The patients in the conventional acupoints group received EA at the tender point of the lesion part, Zhibian( 秩边BL54), Huantiao(环跳 GB30),weǐzhōng(委中BL40), Chéngshān(承山BL57) and Fúyáng(跗阳BL59) on the affected side. The retain time of the needles is both 45 min. The treatment of the two groups is 3 times a week and for a connective 20 times. The modified Assessment Criteria for Low Lumbar Pain of Japanese Orthopedic Association(JOA),Visual Analogue Scale(VAS) were evaluated before and after the treatment and at the 6-month follow up.Results:(1) Effective outcomes. JOA score: The JOA score of the patients in the EX-B2 group after treatment was(20.89 士 3.43), and was(19.35 ±4.02) on the follow-up. Compared with the JOA score(12.35 ±4.42) in the same group before the treatment, there were statistical significant higher(both P0.05). The JOA score in the EX-B2 group after treatment and on the follow-up were both higher than that of the conventional acupoints group at the same time point(both P0.05). VAS score: The VAS score of the patients in the EX-B2 group on the 24 h after the first treatment was(4.09 ± 1.81), and was(2.11 ± 1.30) after the treatment. Compared with the VAS score(4.09 ± 1.81) in the same group before the treatment, there were statistical significant lower(both P0.05). The VAS score in the EX-B2 group on the 24 h after the first treatment and after treatment showed no statistical differences than that of the conventional acupoints group at the same time point(both P0.05).(2)Related results from data mining: The middle-aged people and disease duration less than six months, their effect of the immediate treatment was the best. According to JOA score, EA at EX-B2 was better than EA conventional acupoints,either in the process of treatment effect, or in pertinence of the treatment, which were superior to EA conventional acupoints therapy; The best curative effect time of EA at EX-B2 was the first treatment after24 h, and the best curative effect of the conventional acupoints was after the first treatment. The age and disease duration also affected curative effect.Conclusion: The effect of EA at EX-B2 was superior to the conventional acupoints in treating LIDH. 展开更多
关键词 ELECTROACUPUNCTURE jiājǐ(夹脊 ex-b2 Lumber intervertebral disc herniation Association algorithm Decision tree Grey slope correlation algorithm Effect
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Observation on efficacy of treating vascular dementia gait disorder with electro-acupuncture(EA) on Jiājǐ(夹脊 EX-B2) along lumbar vertebra combined with scalp acupuncture 被引量:2
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作者 冯罡 《World Journal of Acupuncture-Moxibustion》 2014年第2期1-5,共5页
Objective To observe the efficacy of treating vascular dementia gait disorder with electroacupuncture (EA) on Jiaji (夹脊EX-B2) along the lumbar vertebra combined with scalp acupuncture, in order to explore a more... Objective To observe the efficacy of treating vascular dementia gait disorder with electroacupuncture (EA) on Jiaji (夹脊EX-B2) along the lumbar vertebra combined with scalp acupuncture, in order to explore a more effective therapeutic method. Methods Forty-two patients were divided into an acupuncture group and a drug group according to the method of random number table, with 21 cases in each group. EA on EX-B2 from L2 to L5 (bilateral) and scalp acupuncture on Baihui (百会 CV 20) and Sishencong (四神聪EX-HN 1) were applied in the acupuncture group, once a day the course of treatment was 30 days; Duxil was taken orally by the drug group, one pill twice a day for 30 days as a course of treatment. After treatment was completed, the efficacy was evaluated and activities of daily living (ADL) were compared between the two groups. Results The total effectiveness rate for the acupuncture group was 90.5%, which was significantly better than that of the drug group (61.9%), and the differences were statistically significant (P〈0.05); ADL was compared before and after treatment, and the differences were statistically significant (the acupuncture group: 24.52±9.34 vs 32.85±13.56; the drug group: 25.47±10.04 vs 29.99±13.87, both P〈0.01); after treatment, ADL, including gait disorders, in the acupuncture group was more significantly improved than that of the drug group, and the differences were statistically significant (32.85±13.56 vs 29.99± 13.87, P〈0.01). Conclusion The efficacy of treating vascular dementia gait disorder with electro-acupuncture (EA) on EX-B2 along lumbar vertebra combined with scalp acupuncture was superior to orally administered Duxil. 展开更多
关键词 ELECTRO-ACUPUNCTURE ex-b2 scalp acupuncture vasculardementia gait disorders randomized controlled trial KEY WORDS: electro-acupuncture ex-b2 scalp acupuncture vasculardementia gait disorders randomized controlled trial
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Effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury
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作者 Hui-Jie Chen Xiu-Ming Pang +1 位作者 Song-Yin Zheng Yan Wang 《Journal of Hainan Medical University》 2019年第22期22-26,共5页
Objective:To observe the effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury. Methods:SD rats were randomly divided into s... Objective:To observe the effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury. Methods:SD rats were randomly divided into sham-operated group, model group, electro-acupuncture group and methylprednisolone group. The model of acute spinal cord injury was reproduced by modified Allen's method. Each group was given corresponding intervention treatment 2 hours after modeling. The electroacupuncture group was treated with electro-acupuncture at Jiaji (EX-B2) points in T8 to T12, the methylprednisolone group was given intraperitoneal injection of 30 mg/kg methylprednisolone sodium succinate, and the sham operation group and model group were not treated. After treatment, BBB scores were observed to evaluate the motor function of posterior limb in each group, and the injured spinal cord tissues were taken. The pathological changes of spinal cord neuropathy were observed by Nissl staining. The expression of microRNA-21 was detected by RT-qPCR, and the expression of apoptotic proteins (Bax, Bcl-2 and cleaved-Caspase-3) was detected by Western-Blot. Result:Compared with sham operation group, BBB, neuron survival rate and expression of microRNA-21 were significantly lower, apoptotic rate of neurons was significantly higher, expression of Bax, Bcl-2, cleaved Caspase-3 protein and Bax/Bcl-2 ratio were significantly increased in model group (P< 0.05). Electroacupuncture could significantly increase BBB score, neuron survival rate and expression of microRNA-21, reduce apoptotic rate of neurons and the ratio of Bax/Bcl-2, and inhibit the expression of Bax, Bcl-2 and cleaved Caspase-3 protein in tissues, which were significantly different from those of model group (P< 0.05). Conclusions: Electroacupuncture at Jiaji (EX-B2) points can significantly promote the recovery of neurological function in rats after ASCI, and its mechanism may be closely related to the up-regulation of the expression of microRNA-21 in tissues and the inhibition of the activation of Bax/Bcl-2/cleaved Caspase-3 signaling pathway. 展开更多
关键词 Jiaji(ex-b2)points ELECTROACUPUNCTURE Acute spinal cord injury Apoptosis MICRORNA-21
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基于JAK2/STAT3通路探讨“夹脊”电针治疗脊髓损伤大鼠的神经元凋亡作用机制
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作者 蒋焕莹 张东旭 +7 位作者 孙忠人 焦雪峰 周明园 黄飞 洛子茹 孙美琦 开心 尹洪娜 《针刺研究》 北大核心 2025年第6期633-640,共8页
目的:基于Janus酪氨酸蛋白激酶(JAK)/信号转导及转录激活因子(STAT)信号通路观察电针“夹脊”对脊髓损伤大鼠神经元凋亡的影响,探讨电针治疗脊髓损伤的可能机制。方法:将36只SD大鼠随机分为假手术组、脊髓损伤组、夹脊电针组,每组12只... 目的:基于Janus酪氨酸蛋白激酶(JAK)/信号转导及转录激活因子(STAT)信号通路观察电针“夹脊”对脊髓损伤大鼠神经元凋亡的影响,探讨电针治疗脊髓损伤的可能机制。方法:将36只SD大鼠随机分为假手术组、脊髓损伤组、夹脊电针组,每组12只。采用Allen’s法制备脊髓损伤模型。夹脊电针组给予电针“夹脊”治疗(每日1次,30 min/次,共14 d)。治疗结束后对各组大鼠进行BBB评分评估大鼠后肢运动功能;HE染色观察脊髓组织形态;TUNEL染色观察脊髓病理改变及神经元凋亡率;Western blot法检测脊髓磷酸化(p)-JAK2、p-STAT3、B细胞淋巴瘤-2(Bcl-2)、Bcl-2相关X蛋白(Bax)、天冬半胱氨酸特异性蛋白酶-3(Caspase-3)蛋白的相对表达量。结果:与同时间点假手术组比较,脊髓损伤组BBB评分降低(P<0.01);损伤区脊髓组织结构紊乱,胞体皱缩,神经元凋亡率升高(P<0.01);p-JAK2、p-STAT3、Bax、Caspase-3蛋白表达水平升高(P<0.01),Bcl-2蛋白表达水平降低(P<0.01)。与脊髓损伤组比较,夹脊电针组大鼠干预第7、14天时BBB评分升高(P<0.01);脊髓组织结构趋于正常,神经元受损程度减轻,神经元凋亡率下降(P<0.01);p-JAK2、p-STAT3、Bax、Caspase-3蛋白表达水平降低(P<0.01,P<0.05),Bcl-2蛋白表达水平升高(P<0.05)。结论:电针“夹脊”可改善脊髓损伤大鼠运动功能,上调抗凋亡因子的表达,下调促凋亡因子的表达,减少损伤脊髓中神经元的凋亡,其机制可能与抑制JAK2/STAT3信号通路的激活有关。 展开更多
关键词 脊髓损伤 夹脊 电针 细胞凋亡 Janus酪氨酸蛋白激酶(JAK)/信号转导及转录激活因子(STAT)信号通路
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Spinal stenosis treated with acupuncture on Huátuó Jiájǐ(夹脊EX-B 2) and vertebral curvature adjustment:report of therapeutic effect on 189 cases 被引量:4
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作者 韦以宗 王秀光 +4 位作者 戴国文 田新宇 潘东华 韦春德 高腾 《World Journal of Acupuncture-Moxibustion》 2009年第1期22-29,34,共9页
Objective To observe the clinical effects on spinal stenosis treated with acupuncture on Huatuo Jiaji (夹脊EX-B 2) and vertebral curvature adjustment. Methods Comprehensive therapy was applied to all of 189 cases of... Objective To observe the clinical effects on spinal stenosis treated with acupuncture on Huatuo Jiaji (夹脊EX-B 2) and vertebral curvature adjustment. Methods Comprehensive therapy was applied to all of 189 cases of any type of spinal stenosis, in which gukong needling technique was applied to Huatuo Jiaji (夹脊EX-B 2) at C4 - T5 and T12 - L5, associated with vertebral curvature adjustment with traction. The therapeutic effects were observed. Results Total effective rate was 96.8%, in which, clinical cured rate was 31.7% and excellent and good rate was 89.9% in average 28-month fol- low-up visit. Conclusion Spinal stenosis is segmental dynamic stenosis. It can be cured by acupuncture on Huatuo Jiaji (夹脊EX-B 2) and vertebral curvature adjustment and satisfactory result is achieved. 展开更多
关键词 Huatuo Jiaji (夹脊ex-b 2 gukong Needling Four Dimensional Suspension Traction Vertebral Curvature Adjustment Spinal Stenosis
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Intractable post-herpetic neuralgia in the trunk treated with point injection at Jiájǐ(夹脊 EX-B 2) 被引量:1
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作者 蔡正良 瞿平元 +1 位作者 李亚琴 刘岩峥 《World Journal of Acupuncture-Moxibustion》 2011年第1期33-37,共5页
ABSTRACT Objective To compare the efficacy difference between point injection at Jiiaji (夹脊 EX-B 2) and oral medication in the treatment of intractable post-herpetic neuralgia (PHN) in the trunk. Methods One hun... ABSTRACT Objective To compare the efficacy difference between point injection at Jiiaji (夹脊 EX-B 2) and oral medication in the treatment of intractable post-herpetic neuralgia (PHN) in the trunk. Methods One hundred and thirty cases were randomly divided into an point injection group and an medication group, 65 cases in each one. In point injection group, according to the invasion site of herpes zoster, Jiiaji (夹脊 EX-B 2) of corresponding segments and the meridian points on skin lesion areas, such as Fengchi (风池GB 20), Tianzhu (天柱 BL 10), Feishu (肺俞 BL 13) and Geguan (膈关 BL 46) were selected and injected with the mixed solution of compound Betamethasone (administered only in the first injection), Vitamin B12 and Lidoeaine Carbonate, 2 mL on each point, once per day. In medication group, Diclofenac Sodium sustained release tablets, 75 mg were administered, twice per day. The clinical efficacy was compared 10 days later between two groups. Results The total effective rate in point injection group was 100.0% (65/65), which was better than 66.1% (43/65) in medication group (P〈0.01). Conclusion Point injection mainly at Jiiaji (夹脊 EX-B 2) is effective significantly on intractable PHN in the trunk, which is superior to Diclofenac Sodium sustained release tablets. 展开更多
关键词 Herpes Zoster NEURALGIA HYDRO-ACUPUNCTURE Point ex-b 2 (Jiaji)
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Efficacy observation on cervical spondylosis of nerve root type treated by the warm needling at Jiájǐ(夹脊EX-B 2) and tapping with plum-blossom needle 被引量:1
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作者 刘敏娟 穆敬平 +2 位作者 郑苏 任昌菊 WANG Fang 《World Journal of Acupuncture-Moxibustion》 2013年第4期6-10,共5页
Objective To observe the clinical effect on cervical spondylosis of nerve root type treated by warm needling therapy at Jiáj (夹脊 EX-B 2) and plum-blossom needle therapy. Methods According to the random number... Objective To observe the clinical effect on cervical spondylosis of nerve root type treated by warm needling therapy at Jiáj (夹脊 EX-B 2) and plum-blossom needle therapy. Methods According to the random number table, 150 cases of cervical spondylosis of nerve root type were randomized into an acupuncture-moxibustion group (75 cases) and a control group (75 cases). In the acupuncture-moxibustion group, the warm needling at EX-B 2 and tapping with plum-blossom needle were applied. EX-B 2 on the affected segments were selected and stimulated with warm needling technique for 20– 30 min. Afterward, the plum-blossom needle was used to tap the skin around the acupoints, for 3 min on each site. The treatment was given once every day. Seven treatments made one session. The interval between two sessions was 1 day. In the control group, the medication was used in combination with traction therapy. The intravenous drip with 5% glucose 250 mL and compound salvia miltiorrhiza injection 40 mL was used, once a day. In traction treatment, the patient was in a sitting position, neck anteflexion at 15°–30°, traction force at 10%–20% of the body mass, for 20–30 min in each time. The treatment was given once every day. The appointed person evaluated therapeutic effects after the three sessions of treatment in the two groups. Results The clinical curative rate was 49.3% (37/75) and the total effective rate was 94.7% (71/75) in the acupuncture-moxibustion group and those were 24.0% (18/75) and 81.3% (61/75) respectively in the control group. The total effective rate and clinical curative rate in the acupuncture-moxibustion group were superior to the control group (both P0.05). In the comparison of the duration of treatment and effect in the cured patients between the two groups, the curative rate in the 1st session of treatment in the acupuncture-moxibustion group was higher than that in the control group (P0.05). In the comparison of the 6-month follow-up visit in the cured patients between the two groups, the effect in the acupuncture-moxibustion group was much more stable (P0.05). Conclusion The warm needling therapy at EX-B 2 and tapping therapy with plum-blossom needle achieve the significant effect on cervical spondylosis of nerve root type. 展开更多
关键词 cervical spondylosis of nerve root type warm needling therapy Jiáj(夹脊 ex-b 2 tapping therapy with plum-blossom needle
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Treatment of 100 Cases of Cervical Spondylotic Radiculopathy by Electroacupuncture of Jiaji(Ex-B2)plus Oblique Needling Ashi Point 被引量:19
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作者 李晓清 周伟光 蒯乐(译) 《Journal of Acupuncture and Tuina Science》 2006年第1期54-55,共2页
Summary: One hundred patients were diagnosed with cervicalspondylotic radiculopathy definitely by symptoms, signs and Xray examination. The therapeutic method was acupuncture of Jiaji(Ex-B 2) on the affected segmen... Summary: One hundred patients were diagnosed with cervicalspondylotic radiculopathy definitely by symptoms, signs and Xray examination. The therapeutic method was acupuncture of Jiaji(Ex-B 2) on the affected segment and the upper and lower vertebrae close together. After the arrival of qi, the needles were connected to acupuncture therapeutic instrument. Meanwhile, the numb, heavy and uncomfortable area on the shoulder and upper limb, where something like cord could be touched, was selected as Ashi point. The needle was inserted perpendicularly into the skin on the place that the cord was most obvious and inserted obliquely and deeply along the cord. After 3 4 courses of treatment, 90 cases got marked effectiveness and 10 cases got effectiveness. 展开更多
关键词 Neck Pain ELECTROACUPUNCTURE Point ex-b 2
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夹脊电针通过miR-128-3p/ATG12轴干预大鼠脊髓损伤后神经功能的机制研究 被引量:2
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作者 吴海波 钟前波 +1 位作者 邓寒冰 冯伦冬 《上海针灸杂志》 CSCD 2024年第8期898-905,共8页
目的分析夹脊电针对大鼠脊髓损伤后神经功能的影响,并探讨其可能机制。方法将40只Wistar大鼠随机分为假手术组、模型组、夹脊电针组以及夹脊电针+anta-miR-128-3p组,每组10只。假手术组与模型组不做处理,夹脊电针组给予电针干预(每日1次... 目的分析夹脊电针对大鼠脊髓损伤后神经功能的影响,并探讨其可能机制。方法将40只Wistar大鼠随机分为假手术组、模型组、夹脊电针组以及夹脊电针+anta-miR-128-3p组,每组10只。假手术组与模型组不做处理,夹脊电针组给予电针干预(每日1次,每次20 min,连续2周),夹脊电针+anta-miR-128-3p组在末次电针刺激后,尾静脉注射anta-miR-128-3p。干预结束后通过行为学(Basso Beattie Bresnahan,BBB)评分评估大鼠运动功能;苏木素-伊红染色与原位末端标记法染色观察大鼠脊髓病理改变以及凋亡情况;免疫荧光法测定脊髓组织神经元特异性核蛋白(neuron-specific nuclear protein,NeuN)阳性表达;qRT-PCR法检测脊髓组织miR-128-3p、自噬相关蛋白12(autophagy-related protein 12,ATG12)mRNA水平;Western blot法检测ATG12蛋白表达;双荧光素酶报告基因验证miR-128-3p与ATG12关系。结果假手术组脊髓结构完整,排列整齐;模型组大鼠脊髓结构紊乱,神经元数量减少,存在大量炎性浸润;夹脊电针组脊髓结构紊乱现象有所减轻,炎性浸润减少;与夹脊电针组比较,夹脊电针+anta-miR-128-3p组脊髓损伤加剧;与假手术组比较,模型组大鼠BBB评分、miR-128-3p水平、NeuN阳性神经元数量降低(P<0.05),凋亡率、ATG12 mRNA水平与ATG12蛋白表达升高(P<0.05);夹脊电针组大鼠BBB评分、miR-128-3p水平、NeuN阳性神经元数量高于模型组(P<0.05),凋亡率、ATG12 mRNA水平与ATG12蛋白表达低于模型组(P<0.05);与夹脊电针组比较,夹脊电针+anta-miR-128-3p组大鼠BBB评分、miR-128-3p水平、NeuN阳性神经元数量降低(P<0.05),凋亡率、ATG12 mRNA水平与ATG12蛋白表达升高(P<0.05);miR-128-3p与ATG12靶向结合。结论夹脊电针可能通过调控miR-128-3p/ATG12轴,改善脊髓损伤大鼠神经功能损伤。 展开更多
关键词 夹脊 电针 脊髓损伤 神经功能 miR-128-3p 自噬相关蛋白12 大鼠
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颈夹脊穴深刺联合颈百劳穴隔姜灸治疗气滞血瘀型神经根型颈椎病的临床研究 被引量:3
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作者 王怀泽 苏毅 +2 位作者 熊应宗 马幸福 朱俊琛 《针灸临床杂志》 2025年第1期51-56,共6页
目的:观察颈夹脊穴深刺联合颈百劳穴隔姜灸治疗神经根型颈椎病的临床疗效。方法:选取2022年12月—2023年12月就诊于安徽中医药大学第二附属医院骨伤科的60例神经根型颈椎病患者,随机分为对照组和观察组。对照组进行颈百劳穴隔姜灸治疗;... 目的:观察颈夹脊穴深刺联合颈百劳穴隔姜灸治疗神经根型颈椎病的临床疗效。方法:选取2022年12月—2023年12月就诊于安徽中医药大学第二附属医院骨伤科的60例神经根型颈椎病患者,随机分为对照组和观察组。对照组进行颈百劳穴隔姜灸治疗;观察组采用颈夹脊穴深刺联合颈百劳穴隔姜灸治疗。两组均治疗2周。观察两组治疗后的临床疗效,比较两组治疗前、后及随访1个月的Northwick Park颈痛量表(NPQ)评分、简化麦吉尔疼痛问卷(SF-MPQ)评分及颈部动脉血流动力学。结果:治疗2周及随访1个月,两组Northwick Park颈痛量表NPQ评分、简化麦吉尔疼痛问卷SF-MPQ评分较治疗前均明显下降,差异具有统计学意义(P<0.05),观察组评分优于对照组,差异具有统计学意义(P<0.05);颈部动脉平均血流速度较治疗前均增加,差异具有统计学意义(P<0.05),观察组平均血流速度优于对照组,差异具有统计学意义(P<0.05);治疗后,观察组优良率为90.00%(27/30),高于对照组的66.67%(20/30),差异具有统计学意义(P<0.05)。结论:颈夹脊穴深刺联合颈百劳穴隔姜灸治疗神经根型颈椎病疗效显著,可明显缓解患者的疼痛、颈部功能及活动度,增加颈部动脉平均血流速度,是一种有效、安全的治疗方式。 展开更多
关键词 神经根型颈椎病 颈夹脊 深刺 颈百劳 隔姜灸
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电针联合穴位贴敷治疗带状疱疹后遗神经痛的疗效观察 被引量:4
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作者 朱世壮 宋庆雨 +1 位作者 刘长玥 杨佃会 《世界中医药》 北大核心 2025年第2期303-308,共6页
目的:观察电针华佗夹脊穴联合穴位贴敷治疗老年带状疱疹后遗神经痛(PHN)气滞血瘀型的临床疗效及对血液T细胞亚群分化群3(CD3^(+))、分化群4(CD4^(+))、分化群8(CD8^(+))和疼痛因子P物质(SP)、β-内啡肽(β-EP)的影响。方法:将100例PHN... 目的:观察电针华佗夹脊穴联合穴位贴敷治疗老年带状疱疹后遗神经痛(PHN)气滞血瘀型的临床疗效及对血液T细胞亚群分化群3(CD3^(+))、分化群4(CD4^(+))、分化群8(CD8^(+))和疼痛因子P物质(SP)、β-内啡肽(β-EP)的影响。方法:将100例PHN患者按随机数字表法随机分为观察组与对照组,每组50例。观察组给予电针患侧相应神经节段的华佗夹脊穴联合消肿止痛贴^(+)中药细粉穴位贴敷,贴敷穴位为三阴交(双侧)、神阙穴、阿是穴(两处),对照组给予口服加巴喷丁胶囊。观察治疗前、治疗4周后2组患者视觉模拟评分法(VAS)评分、中医证候积分、匹兹堡睡眠质量指数(PSQI)、T细胞亚群CD3^(+)、CD4^(+)、CD8^(+)及疼痛因子SP、β-EP含量的变化,并评定2组临床疗效。结果:与治疗前比较,治疗4周后2组VAS评分、中医证候积分、PSQI得分及CD8^(+)、SP水平均降低(P<0.05),且观察组低于对照组(P<0.05);CD3^(+)、CD4^(+)、β-EP含量均升高(P<0.05),且观察组高于对照组(P<0.05)。观察组总有效率为95.74%,高于对照组的77.08%(P<0.05)。结论:电针华佗夹脊穴联合穴位贴敷治疗老年性PHN气滞血瘀型的临床疗效明显优于加巴喷丁胶囊,在减轻患者疼痛症状、中医证候及提升睡眠质量方面疗效更佳,且可降低血液CD8^(+)、SP水平,提升CD3^(+)、CD4^(+)及内源性镇痛物质β-EP含量。 展开更多
关键词 电针 华佗夹脊穴 穴位贴敷 带状疱疹后遗神经痛 加巴喷丁胶囊 T细胞亚群 疼痛因子 疗效观察
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芪参通脉饮Ⅰ号联合电针夹脊穴治疗气虚血瘀型Wagner 0级糖尿病足临床观察 被引量:1
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作者 顾召 林权 +2 位作者 夏联恒 李婉婷 高杰 《山东中医杂志》 2025年第1期48-53,共6页
目的:观察芪参通脉饮Ⅰ号联合电针夹脊穴治疗气虚血瘀型Wagner0级糖尿病足的临床疗效。方法:选择气虚血瘀型Wagner0级糖尿病足患者120例,按随机数字表法分为治疗组和对照组各60例。两组均采用西医常规治疗,对照组在西医常规治疗基础上... 目的:观察芪参通脉饮Ⅰ号联合电针夹脊穴治疗气虚血瘀型Wagner0级糖尿病足的临床疗效。方法:选择气虚血瘀型Wagner0级糖尿病足患者120例,按随机数字表法分为治疗组和对照组各60例。两组均采用西医常规治疗,对照组在西医常规治疗基础上予电针夹脊穴治疗,治疗组在对照组基础上予芪参通脉饮Ⅰ号治疗,两组均治疗28 d。比较两组患者治疗前后的中医证候评分、踝肱指数(ABI)、多伦多临床评分系统(TCSS)评分、神经传导速度、血液流变学指标、微循环血流指标,并评价临床疗效。结果:治疗后,两组患者中医证候评分、TCSS评分、血液流变学指标水平均较治疗前降低(P<0.05),且治疗组低于对照组(P<0.05);两组患者ABI、神经传导速度、微循环血流指标水平均较治疗前升高,且治疗组高于对照组(P<0.05);治疗组总有效率(93.33%)高于对照组总有效率(86.67%),两组临床疗效比较,差异有统计学意义(P<0.05)。结论:芪参通脉饮Ⅰ号联合电针夹脊穴治疗气虚血瘀型Wagner0级糖尿病足疗效确切,能有效促进血液循环,改善下肢神经病变情况。 展开更多
关键词 芪参通脉饮Ⅰ号 电针 夹脊穴 糖尿病足 气虚血瘀 Wagner 0级 多伦多临床评分系统 血液流变学
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针刺开音1号穴配合颈夹脊穴治疗声带小结25例临床观察 被引量:7
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作者 李迎春 龚慧涵 +2 位作者 陶波 郭华民 谢强 《广州中医药大学学报》 CAS 2010年第3期239-241,共3页
【目的】观察针刺开音1号穴配合颈夹脊穴治疗声带小结的临床疗效。【方法】将47例声带小结患者随机分为治疗组25例和对照组22例。治疗组以针刺开音1号穴配合颈夹脊穴3-5为主治疗,对照组以口服金嗓散结丸治疗。2组均以20 d为1个疗程。观... 【目的】观察针刺开音1号穴配合颈夹脊穴治疗声带小结的临床疗效。【方法】将47例声带小结患者随机分为治疗组25例和对照组22例。治疗组以针刺开音1号穴配合颈夹脊穴3-5为主治疗,对照组以口服金嗓散结丸治疗。2组均以20 d为1个疗程。观察2组的临床疗效及安全性。【结果】治疗后治疗组愈显率为56.00%,对照组为36.36%,2组比较差异有显著性意义(P〈0.05)。治疗组患者治疗后的症状积分有明显改善(与治疗前比较,P〈0.05);对照组治疗后的症状积分也有所改善,但与治疗前比较差异无显著性意义(P(0.05)。2组治疗后比较差异有显著性意义(P〈0.05),说明治疗组对症状积分的改善作用明显优于对照组。2组病例均未出现任何不良反应。【结论】针刺开音1号穴配合颈夹脊穴为主治疗声带小结是临床安全有效的治法。 展开更多
关键词 声带小结/针灸疗法 开音1号 颈夹脊
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针刺颈夹脊治疗顽固性呃逆20例 被引量:6
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作者 朱士涛 王贵根 《上海针灸杂志》 北大核心 1998年第1期21-21,共1页
根据神经解剖学原理,针刺第4颈夹脊治疗顽固性呃逆20例,经治疗1~5次全部患者治愈。提示针刺可降低神经兴奋性而达到解除膈肌痉挛。
关键词 呃逆 针灸疗法 夹脊穴
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电针夹脊穴结合中频理疗治疗腰椎间盘突出症28例 被引量:20
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作者 张素杰 何鹏宇 《河南中医》 2015年第6期1427-1429,共3页
目的:观察电针夹脊穴结合中频理疗腰椎间盘突出症的临床疗效。方法:选取腰椎间盘突出症患者90例,随机分为电针夹脊穴组、中频理疗组和综合组各30例。电针夹脊穴组给予电针夹脊穴治疗,中频理疗组给予中频理疗治疗,综合组给予电针夹脊穴... 目的:观察电针夹脊穴结合中频理疗腰椎间盘突出症的临床疗效。方法:选取腰椎间盘突出症患者90例,随机分为电针夹脊穴组、中频理疗组和综合组各30例。电针夹脊穴组给予电针夹脊穴治疗,中频理疗组给予中频理疗治疗,综合组给予电针夹脊穴结合中频理疗治疗。结果:治疗后,综合组JOA评分明显优于电针夹脊穴组和中频理疗组,差异具有统计学意义(P<0.05);综合组有效率为89.29%,电针夹脊穴组有效率为80.77%,中频理疗组有效率为60%,综合组优于电针夹脊穴组、中频理疗组(P<0.05)。结论:电针夹脊穴结合中频理疗治疗腰椎间盘突出症疗效显著。 展开更多
关键词 腰椎间盘突出症 电针夹脊穴 中频理疗
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针刺夹脊穴对卒中后上肢运动功能障碍的影响
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作者 庄竞翔 陈晓彤 +3 位作者 阮传亮 雷慧蓉 陈桂芬 曾萍萍 《中国针灸》 北大核心 2025年第8期1037-1041,共5页
目的:观察针刺夹脊穴对卒中后上肢运动功能障碍的影响。方法:将62例卒中后上肢运动功能障碍患者随机分为观察组(31例,脱落3例)和对照组(31例,脱落2例)。两组均予常规内科治疗及康复训练。对照组予常规针刺治疗,穴取患侧肩髃、曲池、手... 目的:观察针刺夹脊穴对卒中后上肢运动功能障碍的影响。方法:将62例卒中后上肢运动功能障碍患者随机分为观察组(31例,脱落3例)和对照组(31例,脱落2例)。两组均予常规内科治疗及康复训练。对照组予常规针刺治疗,穴取患侧肩髃、曲池、手三里、环跳、阳陵泉、足三里等。观察组在对照组治疗基础上,针刺患侧C_(4)-T_(5)夹脊穴。每天1次,每周5次,共治疗4周。观察两组患者治疗前后拇短展肌和小指展肌运动诱发电位(MEP)潜伏期和波幅,上肢Fugl-Meyer运动功能评定量表(FMA-UE)和Wolf运动功能评定量表(WMFT)评分。结果:与治疗前比较,治疗后两组患者拇短展肌和小指展肌MEP的波幅升高、潜伏期缩短(P<0.05),FMAUE、WMFT评分升高(P<0.05);观察组患者拇短展肌和小指展肌MEP的波幅高于对照组、潜伏期短于对照组(P<0.05),FMA-UE、WMFT评分高于对照组(P<0.05)。结论:针刺夹脊穴可改善卒中后上肢运动功能障碍患者上肢运动神经通路兴奋性,促进上肢运动功能恢复。 展开更多
关键词 卒中后上肢运动功能障碍 针刺 夹脊穴 运动诱发电位
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“夹脊”电针调控PI3K/AKT/mTOR信号通路减轻过敏性哮喘大鼠气道炎性反应的机制研究
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作者 朱涛 李洁 +4 位作者 万红叶 常卜 程艳婷 冀雨芳 冀来喜 《针刺研究》 北大核心 2025年第6期666-674,共9页
目的:从磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(AKT)/哺乳动物雷帕霉素靶蛋白(mTOR)信号通路,探讨“夹脊”电针治疗过敏性哮喘(AA)大鼠气道炎性反应的潜在机制。方法:SD大鼠随机分为空白组、模型组、电针组、西药组,每组10只。采用腹腔注射... 目的:从磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(AKT)/哺乳动物雷帕霉素靶蛋白(mTOR)信号通路,探讨“夹脊”电针治疗过敏性哮喘(AA)大鼠气道炎性反应的潜在机制。方法:SD大鼠随机分为空白组、模型组、电针组、西药组,每组10只。采用腹腔注射及雾化吸入卵清蛋白(OVA)建立AA大鼠模型。电针组电针双侧颈(C)7~胸(T)3“夹脊”,每次20 min;西药组腹腔注射0.5 mg/kg地塞米松溶液。各组干预均1次/d,连续14 d。观察大鼠一般情况并进行行为学评分;HE染色法观察大鼠肺组织病理形态并进行病理评分;ELISA法检测肺泡灌洗液(BALF)中白细胞介素(IL)-4、IL-5、IL-13及血清免疫球蛋白E(IgE)的含量;免疫组织化学法检测大鼠肺组织苄氯素-1(Beclin1)、微管相关蛋白1A/1B轻链3B(LC3B)的阳性表达;Western blot法检测并计算大鼠肺组织磷酸化(p)-PI3K/PI3K、p-AKT/AKT、p-mTOR/mTOR的蛋白相对表达量的比值。结果:与空白组比较,模型组大鼠体质量下降(P<0.01),出现呼吸急促、喘息、烦躁等症状且行为学评分升高(P<0.01),肺组织病理评分及BALF中IL-4、IL-5、IL-13和血清IgE含量增加(P<0.01),肺组织p-PI3K/PI3K、p-AKT/AKT、p-mTOR/mTOR比值均降低(P<0.01),Beclin1、LC3B阳性表达升高(P<0.01)。与模型组比较,电针组大鼠体质量升高(P<0.05);电针组、西药组大鼠喘息、烦躁症状得到改善且行为学评分和肺组织病理评分降低(P<0.05,P<0.01),BALF中IL-4、IL-5、IL-13及血清IgE含量减少(P<0.01,P<0.05),肺组织p-PI3K/PI3K、p-AKT/AKT、p-mTOR/mTOR比值升高(P<0.05,P<0.01),Beclin1、LC3B阳性表达降低(P<0.01,P<0.05)。电针组与西药组相比差异均无统计学意义。结论:“夹脊”电针可能通过调控PI3K/AKT/mTOR信号通路抑制AA大鼠肺组织中气道上皮细胞的自噬水平,减轻气道炎性反应。 展开更多
关键词 过敏性哮喘 电针 夹脊 磷脂酰肌醇3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白信号通路 自噬
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THE TREATMENT OF CERVICAL SPONDYLOPATHY BY LASER ACUPUNCTURE AT THE CERVICAL JIAJI POINTS: AN ANALYSIS OF THERAPEUTIC EFFECT OF 102 CASES
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作者 Shan Qiuhua, Qin Pengxiu, Xiao FeiAcupuncture and Moxibustion Department, The Affiliated Hospital of Shandong College of Traditional Chinese Medicine, Jinan 250011, China 《World Journal of Acupuncture-Moxibustion》 1994年第1期6-8,19,共4页
Laser acupuncture therapy was employed in the treatment of spondylopathy.Thetherapeutic effect of the three types of the spondylopathy,nerve root type,vertebral artery type andspinal cord type were stuied and compared... Laser acupuncture therapy was employed in the treatment of spondylopathy.Thetherapeutic effect of the three types of the spondylopathy,nerve root type,vertebral artery type andspinal cord type were stuied and compared.The results indicate a significant difference between thethree types of spondylopathy.The best therapeutic effect was obtained in nerve root type with a remarkable effective rate of 98.5%;the effective rates for the vertebral artery type and the spinal cordtype were 92.3%and 25%,respectively.Combining laser irradiatlon with acupuncture,the therapyposseses the functions of acupuncture,heat effect and mild moxibustion action.Therefore,it showedeffect quickly and had the advantages of short treatment course and high therapeutic effect.Clinicalobservation has confirmed that laser acupuncture is more effective than single laser irradiation.Thistherapy offers another simple but effective method for the treatment of spondylopathy. 展开更多
关键词 Osteophytosis SPONDYLOPATHY Laser ACUPUNCTURE JIAJI POINTS (ex-b2)
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温肾养肝方加减联合针刺夹脊穴治疗对帕金森患者非运动症状的影响
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作者 黄彪 刘大同 程惠 《中华保健医学杂志》 2025年第2期231-234,共4页
目的 探讨温肾养肝方加减联合针刺夹脊穴治疗帕金森(PD)患者非运动症状的影响。方法 回顾性分析2021年5月~2024年5月在庐江县中医院接受治疗的64例PD患者临床资料,依据治疗方式不同分成对照组(n=33)与观察组(n=31)。对照组接受常规治疗... 目的 探讨温肾养肝方加减联合针刺夹脊穴治疗帕金森(PD)患者非运动症状的影响。方法 回顾性分析2021年5月~2024年5月在庐江县中医院接受治疗的64例PD患者临床资料,依据治疗方式不同分成对照组(n=33)与观察组(n=31)。对照组接受常规治疗,观察组接受温肾养肝方加减联合针刺夹脊穴治疗。分析两组患者非运动症状量表(NMSS)、帕金森睡眠量表(PDSS)、帕金森综合评分量表(UPDRS)及帕金森病生活质量量表(PDQ-39)得分变化;比较两组患者炎性指标、氧化应激指标;统计两组患者不良反应发生率。结果 治疗后,观察组NMSS各维度得分均低于对照组,差异有统计学意义(t=3.489、2.645、2.865、2.365、3.286、2.303、2.955,P<0.05);UPDRS及PDQ-39得分均低于对照组,PDSS得分均高于对照组,差异有统计学意义(t=3.653、3.142、3.432,P<0.05)。观察组白介素-6、可溶性白介素-2受体水平均低于对照组,差异有统计学意义(t=3.618、2.225,P<0.05)。两组患者不良反应发生率比较差异无统计学意义(P=0.729)。结论 温肾养肝方加减联合针刺夹脊穴能提高对PD患者非运动症状及炎症反应的改善效果,可提高睡眠质量与生活质量,安全性较好。 展开更多
关键词 温肾养肝方 针刺 夹脊穴 帕金森 非运动症状
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