Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often stru...Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.展开更多
太赫兹成像技术虽已被证实能够用于检测葵花籽内部品质,然而其成像速度较为缓慢,难以实现切实且迅速的检测。为了实现对葵花籽饱满度的快速检测,该研究将压缩感知与注意力增强超分辨率生成对抗网络(A-ESRGAN)模型相结合应用于太赫兹成...太赫兹成像技术虽已被证实能够用于检测葵花籽内部品质,然而其成像速度较为缓慢,难以实现切实且迅速的检测。为了实现对葵花籽饱满度的快速检测,该研究将压缩感知与注意力增强超分辨率生成对抗网络(A-ESRGAN)模型相结合应用于太赫兹成像领域。首先,选用压缩采样匹配追踪(compressive sampling matching pursuit,CoSaMP)重构算法来验证不同测量矩阵的性能,根据最佳综合性能选取高斯矩阵作为测量矩阵。其次,通过比较基于交替方向乘子法(alternating direction method of multipliers,ADMM)结合全变分(total variation,TV)正则化(ADMM_TV)和子空间追踪(subspace pursuit,SP)等5种重构算法的峰值信噪比和重构时间等评价指标评估图像重建质量。结果表明ADMM_TV在峰值信噪比、均方误差、结构相似性指数表现最佳,自然图像质量评估器在测量比例超过6.0%最低,尽管重构时间无明显优势,但综合表现优于其他算法。最后,运用多尺度注意力增强超分辨率生成对抗网络(A-ESRGANmulti)模型对压缩感知不同采样率的重构图像进行处理,其效果优于真实图像增强超分辨率生成对抗网络(RealESRGAN)和单尺度注意力增强超分辨率生成对抗网络(A-ESRGAN-single),提升了图像质量,使边缘对比度得以提高,为后续的图像分割提供了便利。研究表明,压缩感知与A-ESRGAN-multi模型相结合用于检测葵花籽饱满度是可行的,验证集的饱满度误差平均为2.50%,最大检测误差为6.41%。综上所述,将压缩感知与A-ESRGAN-multi模型相结合,能够有效地节省82.5%的采样时间,为葵花籽的品质检测开辟了新的途径。展开更多
基金funded by the Deanship of Graduate Studies and Scientific Research at Jouf University under grant No.(DGSSR-2025-02-01295).
文摘Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.
文摘太赫兹成像技术虽已被证实能够用于检测葵花籽内部品质,然而其成像速度较为缓慢,难以实现切实且迅速的检测。为了实现对葵花籽饱满度的快速检测,该研究将压缩感知与注意力增强超分辨率生成对抗网络(A-ESRGAN)模型相结合应用于太赫兹成像领域。首先,选用压缩采样匹配追踪(compressive sampling matching pursuit,CoSaMP)重构算法来验证不同测量矩阵的性能,根据最佳综合性能选取高斯矩阵作为测量矩阵。其次,通过比较基于交替方向乘子法(alternating direction method of multipliers,ADMM)结合全变分(total variation,TV)正则化(ADMM_TV)和子空间追踪(subspace pursuit,SP)等5种重构算法的峰值信噪比和重构时间等评价指标评估图像重建质量。结果表明ADMM_TV在峰值信噪比、均方误差、结构相似性指数表现最佳,自然图像质量评估器在测量比例超过6.0%最低,尽管重构时间无明显优势,但综合表现优于其他算法。最后,运用多尺度注意力增强超分辨率生成对抗网络(A-ESRGANmulti)模型对压缩感知不同采样率的重构图像进行处理,其效果优于真实图像增强超分辨率生成对抗网络(RealESRGAN)和单尺度注意力增强超分辨率生成对抗网络(A-ESRGAN-single),提升了图像质量,使边缘对比度得以提高,为后续的图像分割提供了便利。研究表明,压缩感知与A-ESRGAN-multi模型相结合用于检测葵花籽饱满度是可行的,验证集的饱满度误差平均为2.50%,最大检测误差为6.41%。综上所述,将压缩感知与A-ESRGAN-multi模型相结合,能够有效地节省82.5%的采样时间,为葵花籽的品质检测开辟了新的途径。
