To elucidate the mechanism by which supercritical CO_(2)(SCCO_(2))-water-shale interactions during CO_(2)energized fracturing influence proppant embedment in lacustrine shale,shale samples from the Bohai Bay Basin wer...To elucidate the mechanism by which supercritical CO_(2)(SCCO_(2))-water-shale interactions during CO_(2)energized fracturing influence proppant embedment in lacustrine shale,shale samples from the Bohai Bay Basin were selected for SCCO_(2)-water-shale interaction experiments.X-ray diffraction(XRD),SEM large-area high-resolution imaging,automated mineral identification and characterization system(AMICS),and nanoindentation tests were employed to examine the micro-mechanical damage mechanisms of fracture surfaces and the evolving patterns of proppant embedment characteristics.The results reveal that:Prolonged interaction time reduces the contents of dolomite,feldspar,and clay minerals,while quartz content increases,with dolomite showing the most pronounced dissolution effect.As interaction time increases,the hardness and elasticity modulus of shale follow a power-law decay pattern,with the peak degradation rate occurring at 1 d,followed by a gradual decline of degradation velocity.Increasing interaction time results in growth in both the number and depth of embedment pits on the sample surface.After more than 3 d of interaction,clustered proppant embedment is observed,accompanied by the formation of deep embedment pits on the surface.展开更多
Objective To observe the clinical efficacy of catgut embedment combined with moxibustion and bloodletting in the treatment of androgenic alopecia and to probe into its therapeutic mechanism. Methods Eighty-four patien...Objective To observe the clinical efficacy of catgut embedment combined with moxibustion and bloodletting in the treatment of androgenic alopecia and to probe into its therapeutic mechanism. Methods Eighty-four patients with androgenic alopecia were divided into catgut embedment group (group A) and western medicine group (group B) on the basis of random number table and according to the order of treatment. For the pateints in group A, Shenguan (肾关) on both sides, Minghuang (明黄) and Zusanli (足三里 ST 36) were selected to receive catgut embedment therapy, once every month, combined with moxibustion on the lower abdomen and local bloodletting treatment. For the patients in group B, finasteride 1mg/d was orally administrated. The treatment period for two groups was 3 months, and the follow-up visit lasted for 3 months. Serum testosterone (T) and estradiol (E2) contents were detected respectively before treatment, after i month and 3 months of treatment and after 3 months of follow-up visit, and the specific values were calculated to make statistical analysis of T, E2, T/E2 and curative effects of the two groups after i month and 3 months of treatment and after 3 months of follow-up visit. Results There was no statistical significance in curative effect between the two groups after i month of treatment (P〉0.05), and the curative effect in group A were better than that in group B after 3 months of treatment or after 3 months of follow-up visit (both P〈0.05); E2 level in group A was lower than that in group A after 3 months of treatment (P〈0.05); T, E2 and T/E2 in group A were all lower than that in group B after 3 month of follow-up visit (all P〈0.05). Conclusion The curative effect of treating androgenic alopecia with catgut embedment, moxibustion and bloodletting is definite, and its mechanism of action may be related to the reduction of T levels and T/E2 values.展开更多
Experimental and theoretical studies of drag embedment plate anchors recently carried out in Tianjin University are summarized in this research paper, which involve a series of important topics relevant to the study o...Experimental and theoretical studies of drag embedment plate anchors recently carried out in Tianjin University are summarized in this research paper, which involve a series of important topics relevant to the study of drag anchors. The techniques for measuring the trajectory and movement direction of drag anchors in soils, the techniques for measuring the moving embedment point and reverse eatenary shape of the embedded drag line, the penetration mechanism and kinematic behavior of drag anchors, the ultimate embedment depth of drag anchors, the movement direction of the anchor with an arbitrary fluke section, the reverse catenary properties of the embedded drag line, the interaetional properties between drag anchor and installation line, the kinematic model of drag anchors in seabed soils, and the analytical method for predicting the anchor trajectory in soils will all be examined. The present work remarkably reduces the uncertainties in design and analysis of drag embedment plate anchors, and is beneficial to improving the application of this new type of drag anchor in offshore engineering.展开更多
Crushing and embedment are two critical downhole proppant degradation mechanisms that lead to a significant drop in production outputs in unconventional oil/gas stimulation projects. These persistent production drops ...Crushing and embedment are two critical downhole proppant degradation mechanisms that lead to a significant drop in production outputs in unconventional oil/gas stimulation projects. These persistent production drops due to the non-linear responses of proppants under reservoir conditions put the future utilization of such advanced stimulation techniques in unconventional energy extraction in doubt. The aim of this study is to address these issues by conducting a comprehensive experimental approach. According to the results, whatever the type of proppant, all proppant packs tend to undergo significant plastic deformation under the first loading cycle.Moreover, the utilization of ceramic proppants(which retain proppant pack porosity up to 75%), larger proppant sizes(which retain proppant pack porosity up to 15.2%) and higher proppant concentrations(which retain proppant pack porosity up to 29.5%) in the fracturing stimulations with higher in-situ stresses are recommended to de-escalate the critical consequences of crushing associated issues. Similarly, the selection of resin-coated proppants over ceramic and sand proppants may benefit in terms of obtaining reduced proppant embedment.In addition, selection of smaller proppant sizes and higher proppant concentrations are suggested for stimulation projects at depth with sedimentary formations and lower in-situ stresses where proppant embedment predominates. Furthermore, correlation between proppant embedment with repetitive loading cycles was studied.Importantly, microstructural analysis of the proppant-embedded siltstone rock samples revealed that the initiation of secondary induced fractures. Finally, the findings of this study can greatly contribute to accurately select optimum proppant properties(proppant type, size and concentration) depending on the oil/gas reservoir characteristics to minimize proppant crushing and embedment effects.展开更多
The overturning stability is vital for the retaining wall design of foundation pits, where the surrounding soils are usually unsaturated due to water draining. Moreover, the intermediate principal stress does affect t...The overturning stability is vital for the retaining wall design of foundation pits, where the surrounding soils are usually unsaturated due to water draining. Moreover, the intermediate principal stress does affect the unsaturated soil strength; meanwhile, the relationship between the unsaturated soil strength and matric suction is nonlinear. This work is to present closed-form equations of critical embedment depth for a rigid retaining wall against overturning by means of moment equilibrium. Matric suction is considered to be distributed uniformly and linearly with depth. The unified shear strength formulation for unsaturated soils under the plane strain condition is adopted to characterize the intermediate principal stress effect, and strength nonlinearity is described by a hyperbolic model of suction angle. The result obtained is orderly series solutions rather than one specific answer; thus, it has wide theoretical significance and good applicability. The validity of this present work is demonstrated by comparing it with a lower bound solution. The traditional overturning designs for rigid retaining walls, in which the saturated soil mechanics neglecting matric suction or the unsaturated soil mechanics based on the Mohr-Coulomb criterion are employed, are special cases of the proposed result. Parametric studies about the intermediate principal stress, matric suction and its distributions along with two strength nonlinearity methods on a new defined critical buried coefficient are discussed.展开更多
Hydraulic fracturing technology plays a key role in improving the recovery rate of shale gas.The improvement of permeability in relation to hydraulic fracturing depends on changes brought about by the proppant on the ...Hydraulic fracturing technology plays a key role in improving the recovery rate of shale gas.The improvement of permeability in relation to hydraulic fracturing depends on changes brought about by the proppant on the fracture structure in reservoirs.Then it is of great significance to describe the microscopic changes during this process by means of an accurate theoretical model.In this study,based on the heterogeneity of shale fracture and the compaction and embedment of a proppant,we proposed a permeability model to examine the combined effects of a proppant and stress to describe the change mechanism in permeability.Further,changes in fracture width and porosity were considered,and a calculation model of fracture compressibility under proppant compaction and embedment was proposed.The difference from previous studies is that the compressibility and permeability of supported fractures can be further quantified and analyzed by this model.Moreover,its rationality was verified by publicly released test data.The results show that,the compressive effect of stress and the embedding of proppant both have a negative impact on shale permeability.展开更多
Stability analysis of gravity retaining wall was currently based on the assumption that the wall had no embedment depth. The effect of earth berm was usually neglected. The present work highlighted the importance of e...Stability analysis of gravity retaining wall was currently based on the assumption that the wall had no embedment depth. The effect of earth berm was usually neglected. The present work highlighted the importance of embedment depth when assessing the seismic stability of gravity retaining walls with the pattern of pure rotation. In the framework of upper bound theorem of limit analysis, pseudo-static method was applied into two groups of parallel rigid soil slices methods in order to account for the effect of embedment depth on evaluating the critical acceleration of wall-soil system. The present analytical solution is identical to the results obtained from using limit equilibrium method, and the two methods are based on different theory backgrounds. Parameter analysis indicates that the critical acceleration increases slowly when the ratio of the embedment depth to the total height of the wall is from 0 to 0.15 and increases drastically when the ratio exceeds 0.15.展开更多
Complete bearing spiral case has not been applied to large power stations in China so far. The proposal of applying complete bearing spiral case necessitates an analysis of the reliability of the spiral case structure...Complete bearing spiral case has not been applied to large power stations in China so far. The proposal of applying complete bearing spiral case necessitates an analysis of the reliability of the spiral case structure and the security of units under various working conditions. In combination with practice of a project, this paper presents a three-dimensional nonlinear finite element static analysis of the concrete using a concrete smeared crack model by means of the well-known finite element method (FEM) software ABAQUS. The stress distribution of the spiral case and reinforcing bars, the range of damages in surrounding concrete, and the displacement of structure are quantified. The computational results indicate that the embedment method ensures the structure's safety in strength. At the same time, the result shows that this embedment is a kind of preponderant method for embedment in aspects of economy and technique of construction, and the application of this embedment method to the hydropower station is feasible provided that some proper engineering measures are taken to constrain the width of the concrete in accord with the code's requirements. The paper proves the security and reliability of the structural design of spiral case in hydropower station accordingly.展开更多
For the issue of proppant embedment in hydraulic fracturing,a new calculation method of embedment depth considering elastic-plastic deformation was proposed based on the mechanism of proppant embedment into rocks by c...For the issue of proppant embedment in hydraulic fracturing,a new calculation method of embedment depth considering elastic-plastic deformation was proposed based on the mechanism of proppant embedment into rocks by combining proppant embedment constitutive equations and contact stresses on the rock-proppant system.And factors affecting embedment depth of proppant were analyzed using the new method.Compared with the elastic embedment model,the results calculated by the new method match well with the experimental data,proving the new method is more reliable and more convenient to make theoretical calculation and analysis.The simulation results show the process of proppant embedment into rocks is mainly elastic-plastic.The embedment depth of monolayer proppants decreases with higher proppant concentration.Under multi-layer distribution conditions,increasing the proppant concentration will not change its embedment depth.The larger the proppant embedment ratio,the more the stress-bearing proppants,and the smaller the embedment depth will be.The embedment depth under higher closure stress is more remarkable.The embedment depth increased with the drawdown of fluid pressure in the fracture.Increasing proppant radius or the ratio of proppant Young’s modulus to rock Young’s modulus can reduce the proppant embedment depth.展开更多
Hydraulic fracturing is designed to form a high-conductivity fracture. The proppant will embed into the formation rock, especially in soft rock, owing to the interaction between proppant and fracture surface after fra...Hydraulic fracturing is designed to form a high-conductivity fracture. The proppant will embed into the formation rock, especially in soft rock, owing to the interaction between proppant and fracture surface after fracture closure. Proppant embedment would reduce the fracture width and then lower the fracture conductivity. According to dimensional analysis, the rock is assumed to be an elastic material. Using the theory of elasticity to describe the stage of elastic deformation and analysis of the corresponding simplified embedding process, the study establish the static computation model of the two-dimensional infinite half plane and three-dimensional infinite half space model of the proppant embedment. According to laboratory results, the calculation model was modified, got an effective correction factor and analyzed the causes of errors, then discussed the factors which have impact on proppant embedment. The result calculated by the model in this paper can be reference of prop- pant optimization in on-site fracturing for a certainty degree.展开更多
Facing the ethical potentials of technology, there appears a new trend in technology assessment (TA) recently, which is techno-ethics embedment that aims embed ethical perspectives within the process of assessing an...Facing the ethical potentials of technology, there appears a new trend in technology assessment (TA) recently, which is techno-ethics embedment that aims embed ethical perspectives within the process of assessing and developing new technologies. There are two basic dimensions of this trend: the role of ethics and the status of technology. By referring these dimensions, I articulate two different TA modes of the techno-ethics embedment: One is the ethical technology assessment (eTA) that appears as a combination of an ethical judge with the objective technological force, while the other is the combination of an engaged ethical participant with an active technological mediator. Moreover, there is an ideal status of this trend that is an engaged ethical participant with an active technological mediator. As the thought of technology accompaniment shows, both the "agency" of human and technology will be embodied to the most in this ideal status of techno-ethics embedment.展开更多
BACKGROUND : Some studies demonstrate that allogenic peripheral nerve segment embedded subcutaneously significantly reduce the infiltration of lymphocyte and decrease immunological reaction.OBJECTIVE : To observe th...BACKGROUND : Some studies demonstrate that allogenic peripheral nerve segment embedded subcutaneously significantly reduce the infiltration of lymphocyte and decrease immunological reaction.OBJECTIVE : To observe the gross shape, optical and electron microscope results of allogenic nerve segment in rats 2 weeks after subcutaneous embedment, and compare with subcutaneous emdedment of autologous nerve segment. DESIGN : A randomized and controlled experiment.SETTING : Department of Orthopaedics of Fifth People's Hospital of Zhengzhou; Department of Orthopaedics,First Hospital Affiliated to Chongqing Medical University.MATERIALS : Totally 30 adult healthy Wistar male rats, with body mass of (200±20) g, were enrolled. Ten rats were chosen as the donors of allogenic nerve transplantation. The other 20 rats were randomly divided into 2 groups: allogenic nerve embedment group and autologous nerve embedment group, with 10 rats in each one. JEM-1220 transmission electron microscope (Japan) and Olympus BX50 optical microscope (Japan) were used. METHODS : This experiment was carried out at the laboratory of Orthopaedic Department, Chongqing Medical University from October 2000 to April 2002. ① Sciatic nerve of donor rats for allogenic nerve transplantation was cut off at 5 mm distant from pelvic strait.15 mm sciatic nerve segment was chosen from lateral part as graft, allogenic nerve embedment group: 15 mm sciatic nerve form the donor rats was embedded in the posterior part of right legs. Autologous nerve embedment group: 15 mm sciatic nerve segment of autologous left side was embedded in the posterior side of right legs. ② Nerve segment embedded subcutaneously was taken out at postoperative 2 weeks and performed gross observation; then 5 samples chosen randomly respectively from 2 groups and given haematoxylin-eosin staining and observation under optical microscope (×400);The other 5 samples were made into ultrathin sections (0.5μm)and observed under transmission electron microscope(×17 000). MAIN OUTCOME MEASURES : Gross shape, optical and electron microscope results of nerve segments of rats between two groups at 2 weeks after subcutaneous embedment. RESULTS : ① Results of gross observation: Appearance of nerve segment was similar between 2 groups. ② Results of optical observation: medullary sheath denaturation, axonotmesis, vascular engorgement, desmoplasia of adventitia and infiltration of inflammatory cells were all found in both 2 groups. Inflammatory reaction was a little more severe in the allogenic nerve embedment group than in the autologous nerve embedment groups.③Results of electron microscope : Similar cataplasia and denaturation of medullary sheath and cataplasia of Schwann cell were all found in the 2 groups. CONCLUSION: Some inflammatory reaction occurs after allogenic nerve embedment, but the activity of Schwann cell is similar to that of peripheral nerve after autologous nerve embedment.展开更多
The rivet joints have been widely applied in aerospace and vehicle fields.During the joining process of the carbon fiber reinforced plastic(CFRP)laminates,the pre-tightening force of pulling-rivet was the key factor t...The rivet joints have been widely applied in aerospace and vehicle fields.During the joining process of the carbon fiber reinforced plastic(CFRP)laminates,the pre-tightening force of pulling-rivet was the key factor to ensure the connection performance.To predict the impact of clamping loads on stress and failure of laminates,the value of stress and damage evolution of the wall of a hole under the pre-tightening force were simulated by the finite element method.The results of the simulation showed that excessive clamping force led to the damage and failure of CFRP in the hole edge.Connection performance together with progressive failure process and failure modes of CFRP laminates with various pre-tightening forces were investigated.A kind of metal embedded parts embedded in the laminates was designed to reduce the damage by the simulation study.Simulation results showed that embedment reduced the failure and damage efficiently.The embedment reduced about 64%of the maximum stress.展开更多
In this paper, we showed how groups are embedded into wreath products, we gave a simpler proof of the theorem by Audu (1991) (see <a href="#ref1">[1]), also proved that a group can be embedded into the...In this paper, we showed how groups are embedded into wreath products, we gave a simpler proof of the theorem by Audu (1991) (see <a href="#ref1">[1]), also proved that a group can be embedded into the wreath product of a factor group by a normal subgroup and also proved that a factor group can be embedded inside a wreath product and the wreath product of a factor group by a factor group can be embedded into a group. We further showed that when the abstract group in the Universal Embedding Theorem is a p-group, cyclic and simple, the embedding becomes an isomorphism. Examples were given to justify the results.展开更多
Establishing renewables on a floating platform in the deep sea needs secure anchoring to the seabed,commonly achieved with drag embedment anchors(DEAs).The conventional design process relies heavily on empirical testi...Establishing renewables on a floating platform in the deep sea needs secure anchoring to the seabed,commonly achieved with drag embedment anchors(DEAs).The conventional design process relies heavily on empirical testing and is often time and resource-intensive,potentially leading to suboptimal designs.This research aims to overcome these limitations by applying an evolutionary optimization algorithm to existing analytical solutions for DEAs,identifying optimal anchor fluke and shank lengths.By leveraging an optimization strategy,we aim to enhance the design process while diminishing the dependency on exhaustive physical testing and high computational cost.We employ the Non-Dominated Sorting Genetic Algorithm Ⅱ(NSGA-Ⅱ)to optimize anchor shapes,with a focus on three key objectives:maximizing embedment depth and bearing capacity,and minimizing anchor volume.The methodology presents a Pareto front,encompassing all optimal solutions based on the formulated objectives,and demonstrates the efficiency of NSGA-Ⅱ as a tool for optimizing anchor shapes.展开更多
Let X = X(t),t < σ (σ is lifespan) be a birth and death process with explosion whose characteristic triple is (α, C, D). For a set $\bar M \subset \bar E = \left\{ {0, 1, 2, \cdots , \infty } \right\}$ , reservi...Let X = X(t),t < σ (σ is lifespan) be a birth and death process with explosion whose characteristic triple is (α, C, D). For a set $\bar M \subset \bar E = \left\{ {0, 1, 2, \cdots , \infty } \right\}$ , reserving the trajectories before the first explosion time τ and decomposing the trajectories after τ for X according to $\bar M$ we obtain a new birth and death process $_{\bar M} X = \left\{ {_{\bar M} X\left( t \right), t < _{\bar M} \tau } \right\}$ . We calculate the average lifetime after τ for $_{\bar M} X$ and corresponding characteristic triple $\left( {_{\bar M} \alpha , _{\bar M} C, _{\bar M} D} \right)_{\bar M} X$ of $_{\bar M} X$ in terms of (α,C, D) and $\bar M$ . This means that a lot of given birth and death processes can be embedded in one and the same birth and death process. If $k \in \bar E$ and $\bar M = \left\{ k \right\}$ , we decompose X into $_k X, k \in \bar E$ .展开更多
Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.Thi...Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.This paper presents a complete design and implementation of a compact autonomous quadcopter capable of trajectory tracking,object detection,precision landing,and real-time telemetry via long-range communication protocols.The system integrates an onboard flight controller running real-time sensor fusion algorithms,a vision-based detection system on a companion single-board computer,and a telemetry unit using Long Range(LoRa)communication.Extensive flight tests were conducted to validate the system’s stability,communication range,and autonomous capabilities.Potential applications in law enforcement,agriculture,search and rescue,and environmental monitoring are also discussed.展开更多
Embedded printing is a highly promising approach for creating complex structures within a yield-stress support bath.However,the accurate prediction and control of printability remain fundamental challenges due to the ...Embedded printing is a highly promising approach for creating complex structures within a yield-stress support bath.However,the accurate prediction and control of printability remain fundamental challenges due to the complex interactions between inks and support baths.Here,we present an artificial intelligence(AI)-driven framework that interprets and predicts embedded printability using rheological data.Using a standardized workflow,we extracted 21 rheological descriptors and established 12 indicators to evaluate structural continuity and geometric fidelity.Interpretable machine learning models revealed that direction-dependent defects are governed by the synergistic interplay among ink yield stress,support bath zero shear viscosity,flow behavior index,and time constant.To enable the prediction of printability in a generalizable manner,we further developed a cascaded neural network,which achieved mean relative prediction errors below 15%across all indicators.Experimental validation using three-dimensional(3 D)-printed constructs and micro-computed tomography(μCT)reconstructions confirmed a strong correlation between predicted and actual fidelity.This work establishes a physics-informed,data-driven paradigm for decoding and optimizing embedded printing,offering broad applicability and providing a robust tool for the rapid pairing of suitable printable ink-support bath combinations.展开更多
With the rapid development of intelligent cyber-physical systems(ICPS),diverse services with varying Quality of Service(QoS)requirements have brought great challenges to traditional network resource allocation.Further...With the rapid development of intelligent cyber-physical systems(ICPS),diverse services with varying Quality of Service(QoS)requirements have brought great challenges to traditional network resource allocation.Furthermore,given the open environment and a multitude of devices,enhancing the security of ICPS is an urgent concern.To address these issues,this paper proposes a novel trusted virtual network embedding(T-VNE)approach for ICPS based combining blockchain and edge computing technologies.Additionally,the proposed algorithm leverages a deep reinforcement learning(DRL)model to optimize decision-making processes.It employs the policygradient-based agent to compute candidate embedding nodes and utilizes a breadth-first search(BFS)algorithm to determine the optimal embedding paths.Finally,through simulation experiments,the efficacy of the proposed method was validated,demonstrating outstanding performance in terms of security,revenue generation,and virtual network request(VNR)acceptance rate.展开更多
Spam emails remain one of the most persistent threats to digital communication,necessitating effective detection solutions that safeguard both individuals and organisations.We propose a spam email classification frame...Spam emails remain one of the most persistent threats to digital communication,necessitating effective detection solutions that safeguard both individuals and organisations.We propose a spam email classification frame-work that uses Bidirectional Encoder Representations from Transformers(BERT)for contextual feature extraction and a multiple-window Convolutional Neural Network(CNN)for classification.To identify semantic nuances in email content,BERT embeddings are used,and CNN filters extract discriminative n-gram patterns at various levels of detail,enabling accurate spam identification.The proposed model outperformed Word2Vec-based baselines on a sample of 5728 labelled emails,achieving an accuracy of 98.69%,AUC of 0.9981,F1 Score of 0.9724,and MCC of 0.9639.With a medium kernel size of(6,9)and compact multi-window CNN architectures,it improves performance.Cross-validation illustrates stability and generalization across folds.By balancing high recall with minimal false positives,our method provides a reliable and scalable solution for current spam detection in advanced deep learning.By combining contextual embedding and a neural architecture,this study develops a security analysis method.展开更多
基金Supported by the National Natural Science Foundation of China(52425402,52204021,52404038)Scientific Research Fund of China University of Petroleum(Beijing)(2462022BJRC002).
文摘To elucidate the mechanism by which supercritical CO_(2)(SCCO_(2))-water-shale interactions during CO_(2)energized fracturing influence proppant embedment in lacustrine shale,shale samples from the Bohai Bay Basin were selected for SCCO_(2)-water-shale interaction experiments.X-ray diffraction(XRD),SEM large-area high-resolution imaging,automated mineral identification and characterization system(AMICS),and nanoindentation tests were employed to examine the micro-mechanical damage mechanisms of fracture surfaces and the evolving patterns of proppant embedment characteristics.The results reveal that:Prolonged interaction time reduces the contents of dolomite,feldspar,and clay minerals,while quartz content increases,with dolomite showing the most pronounced dissolution effect.As interaction time increases,the hardness and elasticity modulus of shale follow a power-law decay pattern,with the peak degradation rate occurring at 1 d,followed by a gradual decline of degradation velocity.Increasing interaction time results in growth in both the number and depth of embedment pits on the sample surface.After more than 3 d of interaction,clustered proppant embedment is observed,accompanied by the formation of deep embedment pits on the surface.
基金Supported by Scientific research projects under Hebei Provincial Administration of Traditional Chinese Medicine:2011142National Natural Science Foundation of China:8107288381172342
文摘Objective To observe the clinical efficacy of catgut embedment combined with moxibustion and bloodletting in the treatment of androgenic alopecia and to probe into its therapeutic mechanism. Methods Eighty-four patients with androgenic alopecia were divided into catgut embedment group (group A) and western medicine group (group B) on the basis of random number table and according to the order of treatment. For the pateints in group A, Shenguan (肾关) on both sides, Minghuang (明黄) and Zusanli (足三里 ST 36) were selected to receive catgut embedment therapy, once every month, combined with moxibustion on the lower abdomen and local bloodletting treatment. For the patients in group B, finasteride 1mg/d was orally administrated. The treatment period for two groups was 3 months, and the follow-up visit lasted for 3 months. Serum testosterone (T) and estradiol (E2) contents were detected respectively before treatment, after i month and 3 months of treatment and after 3 months of follow-up visit, and the specific values were calculated to make statistical analysis of T, E2, T/E2 and curative effects of the two groups after i month and 3 months of treatment and after 3 months of follow-up visit. Results There was no statistical significance in curative effect between the two groups after i month of treatment (P〉0.05), and the curative effect in group A were better than that in group B after 3 months of treatment or after 3 months of follow-up visit (both P〈0.05); E2 level in group A was lower than that in group A after 3 months of treatment (P〈0.05); T, E2 and T/E2 in group A were all lower than that in group B after 3 month of follow-up visit (all P〈0.05). Conclusion The curative effect of treating androgenic alopecia with catgut embedment, moxibustion and bloodletting is definite, and its mechanism of action may be related to the reduction of T levels and T/E2 values.
基金Foundation item: Supported by the National Natural Science Foundation of China (Grant nos. 50639030 and 50979070) and the 863 Program of China (Grant no. 2006AA09Z348).
文摘Experimental and theoretical studies of drag embedment plate anchors recently carried out in Tianjin University are summarized in this research paper, which involve a series of important topics relevant to the study of drag anchors. The techniques for measuring the trajectory and movement direction of drag anchors in soils, the techniques for measuring the moving embedment point and reverse eatenary shape of the embedded drag line, the penetration mechanism and kinematic behavior of drag anchors, the ultimate embedment depth of drag anchors, the movement direction of the anchor with an arbitrary fluke section, the reverse catenary properties of the embedded drag line, the interaetional properties between drag anchor and installation line, the kinematic model of drag anchors in seabed soils, and the analytical method for predicting the anchor trajectory in soils will all be examined. The present work remarkably reduces the uncertainties in design and analysis of drag embedment plate anchors, and is beneficial to improving the application of this new type of drag anchor in offshore engineering.
文摘Crushing and embedment are two critical downhole proppant degradation mechanisms that lead to a significant drop in production outputs in unconventional oil/gas stimulation projects. These persistent production drops due to the non-linear responses of proppants under reservoir conditions put the future utilization of such advanced stimulation techniques in unconventional energy extraction in doubt. The aim of this study is to address these issues by conducting a comprehensive experimental approach. According to the results, whatever the type of proppant, all proppant packs tend to undergo significant plastic deformation under the first loading cycle.Moreover, the utilization of ceramic proppants(which retain proppant pack porosity up to 75%), larger proppant sizes(which retain proppant pack porosity up to 15.2%) and higher proppant concentrations(which retain proppant pack porosity up to 29.5%) in the fracturing stimulations with higher in-situ stresses are recommended to de-escalate the critical consequences of crushing associated issues. Similarly, the selection of resin-coated proppants over ceramic and sand proppants may benefit in terms of obtaining reduced proppant embedment.In addition, selection of smaller proppant sizes and higher proppant concentrations are suggested for stimulation projects at depth with sedimentary formations and lower in-situ stresses where proppant embedment predominates. Furthermore, correlation between proppant embedment with repetitive loading cycles was studied.Importantly, microstructural analysis of the proppant-embedded siltstone rock samples revealed that the initiation of secondary induced fractures. Finally, the findings of this study can greatly contribute to accurately select optimum proppant properties(proppant type, size and concentration) depending on the oil/gas reservoir characteristics to minimize proppant crushing and embedment effects.
基金Project(41202191)supported by the National Natural Science Foundation of ChinaProject(2015JM4146)supported by the Natural Science Foundation of Shaanxi Province,ChinaProject(2015)supported by the Postdoctoral Research Project of Shaanxi Province,China
文摘The overturning stability is vital for the retaining wall design of foundation pits, where the surrounding soils are usually unsaturated due to water draining. Moreover, the intermediate principal stress does affect the unsaturated soil strength; meanwhile, the relationship between the unsaturated soil strength and matric suction is nonlinear. This work is to present closed-form equations of critical embedment depth for a rigid retaining wall against overturning by means of moment equilibrium. Matric suction is considered to be distributed uniformly and linearly with depth. The unified shear strength formulation for unsaturated soils under the plane strain condition is adopted to characterize the intermediate principal stress effect, and strength nonlinearity is described by a hyperbolic model of suction angle. The result obtained is orderly series solutions rather than one specific answer; thus, it has wide theoretical significance and good applicability. The validity of this present work is demonstrated by comparing it with a lower bound solution. The traditional overturning designs for rigid retaining walls, in which the saturated soil mechanics neglecting matric suction or the unsaturated soil mechanics based on the Mohr-Coulomb criterion are employed, are special cases of the proposed result. Parametric studies about the intermediate principal stress, matric suction and its distributions along with two strength nonlinearity methods on a new defined critical buried coefficient are discussed.
基金financially supported by the National Natural Science Foundation of China(Grants No.52064007,51804085,and 51911530203)supported by Guizhou Provincial Science and Technology Projects(Qianke Combination Foundation-ZK[2021]Key 052)
文摘Hydraulic fracturing technology plays a key role in improving the recovery rate of shale gas.The improvement of permeability in relation to hydraulic fracturing depends on changes brought about by the proppant on the fracture structure in reservoirs.Then it is of great significance to describe the microscopic changes during this process by means of an accurate theoretical model.In this study,based on the heterogeneity of shale fracture and the compaction and embedment of a proppant,we proposed a permeability model to examine the combined effects of a proppant and stress to describe the change mechanism in permeability.Further,changes in fracture width and porosity were considered,and a calculation model of fracture compressibility under proppant compaction and embedment was proposed.The difference from previous studies is that the compressibility and permeability of supported fractures can be further quantified and analyzed by this model.Moreover,its rationality was verified by publicly released test data.The results show that,the compressive effect of stress and the embedding of proppant both have a negative impact on shale permeability.
基金Project(41472245)supported by the National Natural Science Foundation of ChinaProject(CQGT-KJ-2014049)supported by the Chongqing Administration of Land,Resources and Housing,ChinaProject(106112014CDJZR200009)supported by the Fundamental Research Funds for the Central Universities,China
文摘Stability analysis of gravity retaining wall was currently based on the assumption that the wall had no embedment depth. The effect of earth berm was usually neglected. The present work highlighted the importance of embedment depth when assessing the seismic stability of gravity retaining walls with the pattern of pure rotation. In the framework of upper bound theorem of limit analysis, pseudo-static method was applied into two groups of parallel rigid soil slices methods in order to account for the effect of embedment depth on evaluating the critical acceleration of wall-soil system. The present analytical solution is identical to the results obtained from using limit equilibrium method, and the two methods are based on different theory backgrounds. Parameter analysis indicates that the critical acceleration increases slowly when the ratio of the embedment depth to the total height of the wall is from 0 to 0.15 and increases drastically when the ratio exceeds 0.15.
基金Supported by the Sustentation Plan Projects for Out-standing Young Teachers of the Ministry of Education (20011879)
文摘Complete bearing spiral case has not been applied to large power stations in China so far. The proposal of applying complete bearing spiral case necessitates an analysis of the reliability of the spiral case structure and the security of units under various working conditions. In combination with practice of a project, this paper presents a three-dimensional nonlinear finite element static analysis of the concrete using a concrete smeared crack model by means of the well-known finite element method (FEM) software ABAQUS. The stress distribution of the spiral case and reinforcing bars, the range of damages in surrounding concrete, and the displacement of structure are quantified. The computational results indicate that the embedment method ensures the structure's safety in strength. At the same time, the result shows that this embedment is a kind of preponderant method for embedment in aspects of economy and technique of construction, and the application of this embedment method to the hydropower station is feasible provided that some proper engineering measures are taken to constrain the width of the concrete in accord with the code's requirements. The paper proves the security and reliability of the structural design of spiral case in hydropower station accordingly.
文摘For the issue of proppant embedment in hydraulic fracturing,a new calculation method of embedment depth considering elastic-plastic deformation was proposed based on the mechanism of proppant embedment into rocks by combining proppant embedment constitutive equations and contact stresses on the rock-proppant system.And factors affecting embedment depth of proppant were analyzed using the new method.Compared with the elastic embedment model,the results calculated by the new method match well with the experimental data,proving the new method is more reliable and more convenient to make theoretical calculation and analysis.The simulation results show the process of proppant embedment into rocks is mainly elastic-plastic.The embedment depth of monolayer proppants decreases with higher proppant concentration.Under multi-layer distribution conditions,increasing the proppant concentration will not change its embedment depth.The larger the proppant embedment ratio,the more the stress-bearing proppants,and the smaller the embedment depth will be.The embedment depth under higher closure stress is more remarkable.The embedment depth increased with the drawdown of fluid pressure in the fracture.Increasing proppant radius or the ratio of proppant Young’s modulus to rock Young’s modulus can reduce the proppant embedment depth.
基金Supported by the Sichuan Youth Science & Technology Foundation (2011JTD0009) the National Natural Science Foundation of China (51074138)
文摘Hydraulic fracturing is designed to form a high-conductivity fracture. The proppant will embed into the formation rock, especially in soft rock, owing to the interaction between proppant and fracture surface after fracture closure. Proppant embedment would reduce the fracture width and then lower the fracture conductivity. According to dimensional analysis, the rock is assumed to be an elastic material. Using the theory of elasticity to describe the stage of elastic deformation and analysis of the corresponding simplified embedding process, the study establish the static computation model of the two-dimensional infinite half plane and three-dimensional infinite half space model of the proppant embedment. According to laboratory results, the calculation model was modified, got an effective correction factor and analyzed the causes of errors, then discussed the factors which have impact on proppant embedment. The result calculated by the model in this paper can be reference of prop- pant optimization in on-site fracturing for a certainty degree.
文摘Facing the ethical potentials of technology, there appears a new trend in technology assessment (TA) recently, which is techno-ethics embedment that aims embed ethical perspectives within the process of assessing and developing new technologies. There are two basic dimensions of this trend: the role of ethics and the status of technology. By referring these dimensions, I articulate two different TA modes of the techno-ethics embedment: One is the ethical technology assessment (eTA) that appears as a combination of an ethical judge with the objective technological force, while the other is the combination of an engaged ethical participant with an active technological mediator. Moreover, there is an ideal status of this trend that is an engaged ethical participant with an active technological mediator. As the thought of technology accompaniment shows, both the "agency" of human and technology will be embodied to the most in this ideal status of techno-ethics embedment.
文摘BACKGROUND : Some studies demonstrate that allogenic peripheral nerve segment embedded subcutaneously significantly reduce the infiltration of lymphocyte and decrease immunological reaction.OBJECTIVE : To observe the gross shape, optical and electron microscope results of allogenic nerve segment in rats 2 weeks after subcutaneous embedment, and compare with subcutaneous emdedment of autologous nerve segment. DESIGN : A randomized and controlled experiment.SETTING : Department of Orthopaedics of Fifth People's Hospital of Zhengzhou; Department of Orthopaedics,First Hospital Affiliated to Chongqing Medical University.MATERIALS : Totally 30 adult healthy Wistar male rats, with body mass of (200±20) g, were enrolled. Ten rats were chosen as the donors of allogenic nerve transplantation. The other 20 rats were randomly divided into 2 groups: allogenic nerve embedment group and autologous nerve embedment group, with 10 rats in each one. JEM-1220 transmission electron microscope (Japan) and Olympus BX50 optical microscope (Japan) were used. METHODS : This experiment was carried out at the laboratory of Orthopaedic Department, Chongqing Medical University from October 2000 to April 2002. ① Sciatic nerve of donor rats for allogenic nerve transplantation was cut off at 5 mm distant from pelvic strait.15 mm sciatic nerve segment was chosen from lateral part as graft, allogenic nerve embedment group: 15 mm sciatic nerve form the donor rats was embedded in the posterior part of right legs. Autologous nerve embedment group: 15 mm sciatic nerve segment of autologous left side was embedded in the posterior side of right legs. ② Nerve segment embedded subcutaneously was taken out at postoperative 2 weeks and performed gross observation; then 5 samples chosen randomly respectively from 2 groups and given haematoxylin-eosin staining and observation under optical microscope (×400);The other 5 samples were made into ultrathin sections (0.5μm)and observed under transmission electron microscope(×17 000). MAIN OUTCOME MEASURES : Gross shape, optical and electron microscope results of nerve segments of rats between two groups at 2 weeks after subcutaneous embedment. RESULTS : ① Results of gross observation: Appearance of nerve segment was similar between 2 groups. ② Results of optical observation: medullary sheath denaturation, axonotmesis, vascular engorgement, desmoplasia of adventitia and infiltration of inflammatory cells were all found in both 2 groups. Inflammatory reaction was a little more severe in the allogenic nerve embedment group than in the autologous nerve embedment groups.③Results of electron microscope : Similar cataplasia and denaturation of medullary sheath and cataplasia of Schwann cell were all found in the 2 groups. CONCLUSION: Some inflammatory reaction occurs after allogenic nerve embedment, but the activity of Schwann cell is similar to that of peripheral nerve after autologous nerve embedment.
文摘The rivet joints have been widely applied in aerospace and vehicle fields.During the joining process of the carbon fiber reinforced plastic(CFRP)laminates,the pre-tightening force of pulling-rivet was the key factor to ensure the connection performance.To predict the impact of clamping loads on stress and failure of laminates,the value of stress and damage evolution of the wall of a hole under the pre-tightening force were simulated by the finite element method.The results of the simulation showed that excessive clamping force led to the damage and failure of CFRP in the hole edge.Connection performance together with progressive failure process and failure modes of CFRP laminates with various pre-tightening forces were investigated.A kind of metal embedded parts embedded in the laminates was designed to reduce the damage by the simulation study.Simulation results showed that embedment reduced the failure and damage efficiently.The embedment reduced about 64%of the maximum stress.
文摘In this paper, we showed how groups are embedded into wreath products, we gave a simpler proof of the theorem by Audu (1991) (see <a href="#ref1">[1]), also proved that a group can be embedded into the wreath product of a factor group by a normal subgroup and also proved that a factor group can be embedded inside a wreath product and the wreath product of a factor group by a factor group can be embedded into a group. We further showed that when the abstract group in the Universal Embedding Theorem is a p-group, cyclic and simple, the embedding becomes an isomorphism. Examples were given to justify the results.
基金the financial support of the German Research Foundation(DFG)for project number 526159939(Grant GR 1024/61-1).
文摘Establishing renewables on a floating platform in the deep sea needs secure anchoring to the seabed,commonly achieved with drag embedment anchors(DEAs).The conventional design process relies heavily on empirical testing and is often time and resource-intensive,potentially leading to suboptimal designs.This research aims to overcome these limitations by applying an evolutionary optimization algorithm to existing analytical solutions for DEAs,identifying optimal anchor fluke and shank lengths.By leveraging an optimization strategy,we aim to enhance the design process while diminishing the dependency on exhaustive physical testing and high computational cost.We employ the Non-Dominated Sorting Genetic Algorithm Ⅱ(NSGA-Ⅱ)to optimize anchor shapes,with a focus on three key objectives:maximizing embedment depth and bearing capacity,and minimizing anchor volume.The methodology presents a Pareto front,encompassing all optimal solutions based on the formulated objectives,and demonstrates the efficiency of NSGA-Ⅱ as a tool for optimizing anchor shapes.
基金This work was supported by the National Natural Science Foundation of China(Grant No. 10071019) the Centre of Researching Mathematics and Fostering Higher Talent the Ministry of Education of China, and the Natural Science Foundation of Hunan Provi
文摘Let X = X(t),t < σ (σ is lifespan) be a birth and death process with explosion whose characteristic triple is (α, C, D). For a set $\bar M \subset \bar E = \left\{ {0, 1, 2, \cdots , \infty } \right\}$ , reserving the trajectories before the first explosion time τ and decomposing the trajectories after τ for X according to $\bar M$ we obtain a new birth and death process $_{\bar M} X = \left\{ {_{\bar M} X\left( t \right), t < _{\bar M} \tau } \right\}$ . We calculate the average lifetime after τ for $_{\bar M} X$ and corresponding characteristic triple $\left( {_{\bar M} \alpha , _{\bar M} C, _{\bar M} D} \right)_{\bar M} X$ of $_{\bar M} X$ in terms of (α,C, D) and $\bar M$ . This means that a lot of given birth and death processes can be embedded in one and the same birth and death process. If $k \in \bar E$ and $\bar M = \left\{ k \right\}$ , we decompose X into $_k X, k \in \bar E$ .
文摘Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.This paper presents a complete design and implementation of a compact autonomous quadcopter capable of trajectory tracking,object detection,precision landing,and real-time telemetry via long-range communication protocols.The system integrates an onboard flight controller running real-time sensor fusion algorithms,a vision-based detection system on a companion single-board computer,and a telemetry unit using Long Range(LoRa)communication.Extensive flight tests were conducted to validate the system’s stability,communication range,and autonomous capabilities.Potential applications in law enforcement,agriculture,search and rescue,and environmental monitoring are also discussed.
基金supported by the National Natural Science Foundation of China(Nos.52305314 and U21A20394)the Beijing Natural Science Foundation(Nos.7252285 and L246001)the National Key Research and Development Program of China(No.2023YFB4605800)。
文摘Embedded printing is a highly promising approach for creating complex structures within a yield-stress support bath.However,the accurate prediction and control of printability remain fundamental challenges due to the complex interactions between inks and support baths.Here,we present an artificial intelligence(AI)-driven framework that interprets and predicts embedded printability using rheological data.Using a standardized workflow,we extracted 21 rheological descriptors and established 12 indicators to evaluate structural continuity and geometric fidelity.Interpretable machine learning models revealed that direction-dependent defects are governed by the synergistic interplay among ink yield stress,support bath zero shear viscosity,flow behavior index,and time constant.To enable the prediction of printability in a generalizable manner,we further developed a cascaded neural network,which achieved mean relative prediction errors below 15%across all indicators.Experimental validation using three-dimensional(3 D)-printed constructs and micro-computed tomography(μCT)reconstructions confirmed a strong correlation between predicted and actual fidelity.This work establishes a physics-informed,data-driven paradigm for decoding and optimizing embedded printing,offering broad applicability and providing a robust tool for the rapid pairing of suitable printable ink-support bath combinations.
基金supported by the National Natural Science Foundation of China under Grant 62471493supported by the Natural Science Foundation of Shandong Province under Grant ZR2023LZH017,ZR2024MF066。
文摘With the rapid development of intelligent cyber-physical systems(ICPS),diverse services with varying Quality of Service(QoS)requirements have brought great challenges to traditional network resource allocation.Furthermore,given the open environment and a multitude of devices,enhancing the security of ICPS is an urgent concern.To address these issues,this paper proposes a novel trusted virtual network embedding(T-VNE)approach for ICPS based combining blockchain and edge computing technologies.Additionally,the proposed algorithm leverages a deep reinforcement learning(DRL)model to optimize decision-making processes.It employs the policygradient-based agent to compute candidate embedding nodes and utilizes a breadth-first search(BFS)algorithm to determine the optimal embedding paths.Finally,through simulation experiments,the efficacy of the proposed method was validated,demonstrating outstanding performance in terms of security,revenue generation,and virtual network request(VNR)acceptance rate.
基金funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2026R234)Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘Spam emails remain one of the most persistent threats to digital communication,necessitating effective detection solutions that safeguard both individuals and organisations.We propose a spam email classification frame-work that uses Bidirectional Encoder Representations from Transformers(BERT)for contextual feature extraction and a multiple-window Convolutional Neural Network(CNN)for classification.To identify semantic nuances in email content,BERT embeddings are used,and CNN filters extract discriminative n-gram patterns at various levels of detail,enabling accurate spam identification.The proposed model outperformed Word2Vec-based baselines on a sample of 5728 labelled emails,achieving an accuracy of 98.69%,AUC of 0.9981,F1 Score of 0.9724,and MCC of 0.9639.With a medium kernel size of(6,9)and compact multi-window CNN architectures,it improves performance.Cross-validation illustrates stability and generalization across folds.By balancing high recall with minimal false positives,our method provides a reliable and scalable solution for current spam detection in advanced deep learning.By combining contextual embedding and a neural architecture,this study develops a security analysis method.