The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and run...The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and running resistance,and the dynamic models of gear transmission system are not sufficiently comprehensive.This paper aims to establish an electromechanical coupling dynamic model of HST traction transmission system and study its electromechanical coupling vibration characteristics,in which the internal excitation factors such as gear eccentricity,time-varying meshing stiffness,backlash,meshing error,and external excitation factors such as electromagnetic torque and running resistance are stressed.The research results indicate that gear eccentricity and running resistance have a significant impact on the stability of the system,and gear eccentricity leads to intensified system vibration and decreased anti-interference ability.In addition,the characteristic frequency of gear eccentricity can be extracted from mechanical signals and current signals as a preliminary basis for eccentricity detection,and electrical signals can also be used to monitor changes in train running resistance in real time.The results of this study provide some useful insights into designing dynamic performance parameters for HST transmission systems and monitoring train operational states.展开更多
Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is...Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is often proposed as a key stimulus due to its association with increased fascicle length in humans.However,the most efficient exercise stimuli and the effectiveness of eccentric training in increasing SSN remain unclear.The objective of this study was to provide a detailed historical overview of research exploring the mechanical factors regulating muscle/fiber length and its relationship with function,and to explore more recent evidence that eccentric muscle contractions might be an important stimulus for SSN regulation using a meta-analytic approach.Methods An extensive literature search with snowballing was conducted to build the historical review.A systematic review with random-effect meta analyses was performed to compare proposed types of fiber-lengthening exercises to control conditions.Results The historical review demonstrated that the application of forces at long fiber lengths,but not specifically the use of greater excursions,plays an important role in increasing SSN.Animal data showed changes in SSN exceeding 20%over several weeks with varied forms of activities.Nonetheless,the meta-analysis revealed a lack of effect of eccentric resistance training in animal models(Δ=1%;Cohen’s d=0.19(95%confidence interval:–0.29 to 0.67),p=0.449).Conclusion High active or passive muscle forces applied at long fiber lengths appear to be the key stimuli triggering sarcomerogenesis.Eccentric exercise does not seem to be a key promoter of SSN.Too few studies exist to draw conclusions as to the effect of eccentric exercise on SSN in humans.Understanding the mechanical triggers and physiological mechanisms involved in serial sarcomere addition could help in the development of exercise(and other)interventions to optimize muscle function and reduce injury risk.展开更多
The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Train...The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Training the hamstrings 3 times per week for 9 weeks with the Nordic hamstring exercise was found to increase the number of sarcomeres in series in the biceps femoris long head(BFlh)by≥25%.1 In this commentary,we highlight an additional,paradoxical finding,which was not discussed by the authors;namely that the substantial serial sarcomere addition must have been accompanied by a subtraction of sarcomeres in parallel to match the relatively small increase in muscle volume after training.展开更多
Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow f...Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow for sarcomerogenesis are not fully understood.In some diseases,such as cerebral palsy in children,sarcomerogenesis appears to be inhibited or at least reduced,1,2 often causing severe restrictions in muscle and joint function.展开更多
In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking m...In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking mechanism is designed.The push rod iquickly driven by the combined action of the handle and the drum,so that the cross shaft work piece can be quickly locked in the axial direction.The eccentric locking mechanism not only has simple operation and convenient maintenance,but also has the characteristics of low manufacturing cost and high life,and has certain reference value for future special fixture design.展开更多
Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasi...Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.展开更多
Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for...Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for achieving an excellent smooth blasting effect.In this paper,the Riedel-Hiermaier-Thoma(RHT)model was employed to study rock mass damage under smooth blasting.Firstly,the parameters of the RHT model were calibrated by using the existing SHPB experiment,which were then verified by the existing blasting experiment results.Secondly,the influence of different charge structures on the blasting effect was investigated using the RHT model.The simulation results indicated that eccentric charge blasting has an obvious pressure eccentricity effect.Finally,to improve the blasting effect,the smooth blasting parameters were optimized based on an eccentric charge structure.The overbreak and underbreak phenomena were effectively controlled,and a good blasting effect was achieved with the optimized blasting parameters.展开更多
The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a l...The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a little study about the eccentric-gear.And it is necessary to take a further research on eccentric-gear transmission for the applications in the transplanting mechanism of high-speed rice transplanter.The key of this paper is to extend understanding of three following characteristics of this drive:(1)The rotation-center-distance and the geometrical-center-distance of the two meshing eccentric gears are respectively the hypotenuse and the straight edge of a right triangle in a cycle.(2)The geometrical center line of two meshing gears divides the linking-line of the two rotational centers equally.(3)When two times the eccentricity of gear,the rotation-center-distance and the geometrical-center-distance form a right triangle,the optimal value of rotation-center-distance can be determined.In addition,the kinematic analysis,such as the relationship between contact point and midpoint of the linking-line of two gears'rotational centers,transmission ratio between the driving-gear and the driven-gear,contact angle and coordinate of contact point are be made,further the formula for calculation of contact force,flow chart for writing optimization program and curve for analysis of data are also be developed.The relationship between the rotation-center-distance and the geometrical-center-distance,which is determined by three characteristics mentioned above,is a key for the rational design and application of eccentric-gear transmission.Particularly,the presented right triangle property of eccentric gear drive is an important reference for effective analysis of dynamic characteristic of eccentric-gear mechanism and its reliable design.展开更多
The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-...The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-maining approximately constant. The experimental results were provided such as the mean velocity field, fluctuat-ing velocities, turbulent kinetic energy, Reynolds shear stress and time series of the velocity in the stirred tank. These results probably provided the valuable basis to further optimize and enlarge the stirred tank in the industrial process.展开更多
In this paper, the numerical predictions of 3D hydrodynamics and power consumption in a vessel stirred by mul- tiple eccentrically located impellers are presented. The vessel is a fiat-bottomed cylindrical one equippe...In this paper, the numerical predictions of 3D hydrodynamics and power consumption in a vessel stirred by mul- tiple eccentrically located impellers are presented. The vessel is a fiat-bottomed cylindrical one equipped with six-curved bladed impellers. Aqueous solutions of xanthan gum are used, which have a shear thinning behavior with yield stress. The influence of several parameters on the mixing efficiency has been investigated, namely： the stirring rate, fluid theology, impeller number and impeller clearance from the tank bottom. Our predicted results are compared with other experimental data and a satisfactory agreement is found.展开更多
The anchoring eccentricity of the bolt and cable bolt is a common problem in geotechnical support engineering and affects the ability of the bolt and cable bolt to control the rock mass to a certain extent.This paper ...The anchoring eccentricity of the bolt and cable bolt is a common problem in geotechnical support engineering and affects the ability of the bolt and cable bolt to control the rock mass to a certain extent.This paper reports on numerical simulation and laboratory experiments conducted to clarify the effect of eccentricity on the anchoring quality of the bolt and cable bolt,and to establish an effective solution strategy.The results reveal that the anchoring eccentricity causes unbalanced stress distribution and the uncoordinated deformation of the resin layer,which results in higher stress and greater deformation of the resin layer at the near side of the rod body.Additionally,as the degree of anchoring eccentricity increases,the effect becomes more significant,and the resin layer of the anchoring system becomes more likely to undergo preferential failure locally,which weakens the load-bearing performance of the anchoring system.This paper develops an innovative bolt anchoring rectifying device(B-ARD)and cable bolt anchoring rectifying device(C-ARD)on the basis of the structural characteristics of the bolt and cable bolt to better ensure the anchoring effect of them.The working effects of these two devices were verified in detailed experiments and analysis.The experimental results show that the anchoring rectifying devices(ARD)improve and ensure the anchoring concentricity of the bolt and cable bolt,which will help improve the supporting performance of them.The paper provides a convenient and effective method for improving the anchoring concentricity of the bolt and cable bolt,and provides a concept and reference for technical research on improving the effect of roof bolting.展开更多
The location and geometry of large-scale asperity present at the foundation of concrete gravity dams and buttress dams affect the shear resistance of the concrete-rock interface.However,the parameters describing the f...The location and geometry of large-scale asperity present at the foundation of concrete gravity dams and buttress dams affect the shear resistance of the concrete-rock interface.However,the parameters describing the frictional resistance of the interface usually do not account for these asperities.This could result in an underestimate of the peak shear stre ngth,which leads to significantly conservative design for new dams or unnecessary stability enhancing measures for existing ones.The aim of this work was to investigate the effect of the location of first-order asperity on the peak shear strength of a concrete-rock interface under eccentric load and the model discrepancy associated with the commonly used rigid body methods for calculating the factor of safety(FS)against sliding.For this,a series of direct and eccentric shear tests under constant normal load(CNL)was carried out on concrete-rock samples.The peak shear strengths measured in the tests were compared in terms of asperity location and with the predicted values from analytical rigid body methods.The results showed that the large-scale asperity under eccentric load significantly affected the peak shear strength.Furthermore,unlike the conventional assumption of sliding or shear failure of an asperity in direct shear,under the effect of eccentric shear load,a tensile failure in the rock or in the concrete could occur,resulting in a lower shear strength compared with that of direct shear tests.These results could have important implications for assessment of the FS against sliding failure in the concrete-rock interface.展开更多
Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its ea...Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its earliest stage to prevent operation degradation, and malfunction of IMs. An intelligent harmonic synthesis technique is pro- posed in this work to conduct incipient air-gap eccentricity fault detection in IMs. The fault harmonic series are syn- thesized to enhance fault features. Fault related local spectra are processed to derive fault indicators for IM air- gap eccentricity diagnosis. The effectiveness of the pro- posed harmonic synthesis technique is examined experi- mentally by IMs with static air-gap eccentricity and dynamic air-gap eccentricity states under different load conditions. Test results show that the developed harmonic synthesis technique can extract fault features effectively for initial IM air-gap eccentricity fault detection.展开更多
In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable f...In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable for high refining efficiency. Eccentric mechanical stirring with unidirectional impeller rotation was tested using a water model for pursuing better bubble disintegration and dispersion. Absorption rate are used to research on the influence law of the bubble dispersion and disintegration and gas-liquid absorption by the influence of, rotation mode, rotation speed and gas flow rate. Compared to the experimental results of absorption rate under eccentric stirring and centric stirring ,provide the scientific experimental and theoretical guidance for high-temperature experiment of hot metal desulfurization .According to experimental and theoretical analysis, this paper has studied various factors effecting on gas absorption process and volumetric mass transfer coefficient using the system of CO2-NaOH-H2O.The results show that:the volumetric mass transfer coefficient and absorption efficiency of CO2 can be increased under eccentric stirring mode, Because bubble disperse quickly with eccentric mechanical stirring, which results in promoting complete reaction between CO2 and NaOH, and improving the mass transfer coefficient and absorption. Volumetric mass transfer coefficient and efficiency of CO2 increase with the increasing rotation speed under the condition of eccentric stirring .But volumetric mass transfer coefficient and efficiency of CO2 decrease with the increasing rotation speed under the condition of centric stirring.展开更多
Under the effect of eccentric loads,when the suction pressure of the composite bucket foundation is leveled,the seepage failure is very easy to occur.The seepage failure occurrence causes the foundation to settle unev...Under the effect of eccentric loads,when the suction pressure of the composite bucket foundation is leveled,the seepage failure is very easy to occur.The seepage failure occurrence causes the foundation to settle unevenly and impairs the bearing performance.This study uses ABAQUS finite element software to establish a composite bucket foundation model for finite element analysis.The model simulates the seepage of the foundation penetrating process under eccentric load to reveal the induced seepage characteristics of the bucket foundation.The most vulnerable position of seepage failure under the eccentric loading is elucidated.Critical suction formulas for different offset eccentric moment strategies are derived and compared with existing literature formulas.Then the derived formula is supplemented and corrected according to the pressure difference between adjacent cabins.Conclusions can be drawn:(1)Under eccentric loads,the critical suction decreases about 7%−10%.(2)The pressure difference between adjacent cabins impacts significantly on the seepage field,and the critical suction,at most,can be reduced by 17.56%.(3)the offset strategies have little effect on the seepage field.Efficient and appropriate strategies can be selected to meet the requirement of leveling in engineering project.展开更多
With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentatio...With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentation of a type of D-shaped casing, which is a common asymmetric casing in the field of warhead design. Based on the radiograph technique, static explosive experiments were conducted with D-shaped casings under four different eccentric initiation ratios to explore their fragmentation. A numerical model was then established to simulate the dynamic response of D-shaped casing filled with explosive. The results of numerical simulation were found to agree well with the experimental data.According to the results of numerical simulation and experimental data, the dynamic responses of Dshaped casing were analyzed. The results of the current work pave way for the innovative design of new warhead and for further studying the dynamic response of asymmetric casing.展开更多
A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's wef...A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's weft insertion mechanism as well as reduce the manufacturing difficulty. Meanwhile, based on the working principle of this mechanism, kinematical mathematic models of this mechanism were established and an aided analysis and simulation software was compiled. The influences of eccentricity ratio, deformation coefficient, and other important parameters on the kinematics characteristics of this mechanism were analyzed by using the software. A group of preferable parameters which could meet the requirements of weft insertion technology were obtained by means of human-computer interactive optimization method. The maximum velocity, maximum acceleration, and variation of acceleration of this mechanism are smaller than those of the conjugate cam weft insertion mechanism applied on TT96 rapier loom under the conditions of the same unilateral total stroke of rapier head and the same rotary speed of loom spindle; meanwhile the other demands of weaving technology can be met by this novel weft insertion mechanism.展开更多
This work aims to systematically study hydrodynamics and mixing characteristics of non-Newtonian fluid(carboxyl methyl cellulose,CMC)in dual shaft eccentric mixer.Fluid rheology was described by the power law rheologi...This work aims to systematically study hydrodynamics and mixing characteristics of non-Newtonian fluid(carboxyl methyl cellulose,CMC)in dual shaft eccentric mixer.Fluid rheology was described by the power law rheological model.Computational fluid dynamics was employed to simulate the velocity field and shear rate inside the stirred tank.The influence mechanism of the rotational modes,height difference between impellers,impeller eccentricities,and impeller types on the flow field have been well investigated.We studied the performance of different dual-shaft eccentric mixers at the constant power input with its fluid velocity profiles,average shear strain rate,mixing time and mixing energy.The counter-rotation mode shows better mixing performance than co-rotation mode,and greater eccentricity can shorten mixing time on the basis of same stirred condition.To intensify the hydrodynamic interaction between impellers and enhance the overall mixing performance of the dual shaft eccentric mixers,it is critical to have a reasonable combination of impellers and an appropriate spatial position of impellers.展开更多
Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by ...Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by reduced electromyography signal amplitude,diminished evoked H-reflex responses,increased autogenic MN inhibition,and decreased excitability in descending corticospinal motor pathways.Maximum ECC muscle force recorded during maximal voluntary contraction can be increased by superimposed electrical muscle stimulation only in untrained individuals and not in trained strength athletes,indicating that the suppression in MN activation is modifiable by resistance training.In support of this notion,maximum ECC muscle strength can be increased by use of heavy-load resistance training owing to a removed or diminished suppression in neuromuscular activity.Prolonged(weeks to months)of heavy-load resistance training results in increased H-reflex and V-wave responses during maximal ECC muscle actions along with marked gains in maximal ECC muscle strength,indicating increased excitability of spinal MNs,decreased presynaptic and/or postsynaptic MN inhibition,and elevated descending motor drive.Notably,the use of supramaximal ECC resistance training can lead to selectively elevated V-wave responses during maximal ECC contraction,demonstrating that adaptive changes in spinal circuitry function and/or gains in descending motor drive can be achieved during maximal ECC contraction in response to heavy-load resistance training.展开更多
Reinforced concrete(RC)structures are generally designed to carry quasi-static gravity loads through almost indispensable components namely slab,however,it may be subjected to high intense loads induced from the impac...Reinforced concrete(RC)structures are generally designed to carry quasi-static gravity loads through almost indispensable components namely slab,however,it may be subjected to high intense loads induced from the impact of projectiles generated by the tornado,falling construction equipment,and also from accidental explosions during their construction and service lifespan.Impacts due to rock/boulder falls do occur on the structures located especially in hilly areas.Such loadings are not predictable but may cause severe damage to the slab/structure.It stimulates structural engineers and researchers to investigate and understand the dynamic response of RC structures under such impulsive loading.This research work first investigates the performance of 1000×1000×75 mm^(3)conventionally reinforced two-way spanning normal strength concrete slab with only tension reinforcement(0.88%)under the concentric impact load(1035 N)using the finite element method based computer code,ABAQUS/Explicit-v.6.15.The impact load is delivered to the centroid of the slab using a solid-steel cylindroconical impactor(drop weight)with a flat nose of diameter 40 mm,having a total mass of 105 kg released from a fixed height of 2500 mm.Two popular concrete constitutive models in ABAQUS namely;Holmquist-Johnson-Cook(HJC)and Concrete Damage Plasticity(CDP),with strain rate effects as per fib MODEL CODE 2010,are used to model the concrete material behavior to impact loading and to simulate the damage to the slab.The slab response using these two models is analyzed and compared with the impact test results.The strain rate effect on the reinforcing steel bars has been incorporated in the analysis using the Malvar and Crawford(1998)approach.A classical elastoplastic kinematic idealization is considered to model the steel impactor and support system.Results reveal that the HJC model gives a little overestimation of peak displacement,maximum acceleration,and damage of the slab while the predictions given by the CDP model are in reasonable agreement with the experimental test results/observations available in the open literature.Following the validation of the numerical model,analyses have been extended to further investigate the damage response of the slab under eccentric impact loadings.In addition to the concentric location(P1)of the impacting device,five locations on a quarter of the slab i.e.,two along the diagonal(P2&P3),the other two along the mid-span(P4&P5),and the last one(P6)between P3 and P5,covering the entire slab,are considered.Computational results have been discussed and compared,and the evaluation of the most damaging location(s)of the impact is investigated.It has been found that the most critical location of the impact is not the centroid of the slab but the eccentric one with the eccentricity of 1/6th of the span from the centroid along the mid-span section.展开更多
基金supported by Sichuan Science and Technology Program(Grant No.2020YFH0080)the National Natural Science Foundation of China(Grant No.51475386)the National Basic Research Project of China(973 Program,Grant No.2015CB654801).
文摘The gear transmission system directly affects the operational performance of high-speed trains(HST).However,current research on gear transmission systems of HST often overlooks the effects of gear eccentricity and running resistance,and the dynamic models of gear transmission system are not sufficiently comprehensive.This paper aims to establish an electromechanical coupling dynamic model of HST traction transmission system and study its electromechanical coupling vibration characteristics,in which the internal excitation factors such as gear eccentricity,time-varying meshing stiffness,backlash,meshing error,and external excitation factors such as electromagnetic torque and running resistance are stressed.The research results indicate that gear eccentricity and running resistance have a significant impact on the stability of the system,and gear eccentricity leads to intensified system vibration and decreased anti-interference ability.In addition,the characteristic frequency of gear eccentricity can be extracted from mechanical signals and current signals as a preliminary basis for eccentricity detection,and electrical signals can also be used to monitor changes in train running resistance in real time.The results of this study provide some useful insights into designing dynamic performance parameters for HST transmission systems and monitoring train operational states.
文摘Background Serial sarcomere number(SSN)critically influences muscle function and is hypothesized to protect against injury.While most evidence for SSN addition comes from non-human animal studies,eccentric exercise is often proposed as a key stimulus due to its association with increased fascicle length in humans.However,the most efficient exercise stimuli and the effectiveness of eccentric training in increasing SSN remain unclear.The objective of this study was to provide a detailed historical overview of research exploring the mechanical factors regulating muscle/fiber length and its relationship with function,and to explore more recent evidence that eccentric muscle contractions might be an important stimulus for SSN regulation using a meta-analytic approach.Methods An extensive literature search with snowballing was conducted to build the historical review.A systematic review with random-effect meta analyses was performed to compare proposed types of fiber-lengthening exercises to control conditions.Results The historical review demonstrated that the application of forces at long fiber lengths,but not specifically the use of greater excursions,plays an important role in increasing SSN.Animal data showed changes in SSN exceeding 20%over several weeks with varied forms of activities.Nonetheless,the meta-analysis revealed a lack of effect of eccentric resistance training in animal models(Δ=1%;Cohen’s d=0.19(95%confidence interval:–0.29 to 0.67),p=0.449).Conclusion High active or passive muscle forces applied at long fiber lengths appear to be the key stimuli triggering sarcomerogenesis.Eccentric exercise does not seem to be a key promoter of SSN.Too few studies exist to draw conclusions as to the effect of eccentric exercise on SSN in humans.Understanding the mechanical triggers and physiological mechanisms involved in serial sarcomere addition could help in the development of exercise(and other)interventions to optimize muscle function and reduce injury risk.
文摘The first in vivo measurements of serial sarcomere number in human muscles before and after eccentric strength training have just been published and the results will interest anyone involved with sport or health:Training the hamstrings 3 times per week for 9 weeks with the Nordic hamstring exercise was found to increase the number of sarcomeres in series in the biceps femoris long head(BFlh)by≥25%.1 In this commentary,we highlight an additional,paradoxical finding,which was not discussed by the authors;namely that the substantial serial sarcomere addition must have been accompanied by a subtraction of sarcomeres in parallel to match the relatively small increase in muscle volume after training.
文摘Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow for sarcomerogenesis are not fully understood.In some diseases,such as cerebral palsy in children,sarcomerogenesis appears to be inhibited or at least reduced,1,2 often causing severe restrictions in muscle and joint function.
文摘In view of the time-consuming and unreliable deficiencies of the cross-axis work piece in the clamping process,combined with the working characteristics of the eccentric mechanism,a simple and fast eccentric locking mechanism is designed.The push rod iquickly driven by the combined action of the handle and the drum,so that the cross shaft work piece can be quickly locked in the axial direction.The eccentric locking mechanism not only has simple operation and convenient maintenance,but also has the characteristics of low manufacturing cost and high life,and has certain reference value for future special fixture design.
基金Supported by National Natural Science Foundation of China(Grant No.52205455)Fujian Provincial Health Technology Project(Grant Nos.2022CXA005,2022CXA015)。
文摘Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.
基金Projects(11802058,52074262)supported by the National Natural Science Foundation of ChinaProjects(BK20170670,BK20180651)supported by the Jiangsu Youth Foundation,China+2 种基金Project(2020QN06)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(SKLGDUEK1803)supported by the State Key Laboratory for Geomechanics and Deep Underground Engineering,ChinaProject supported by the Mass Entrepreneurship and Innovation Project of Jiangsu,China。
文摘Eccentric decoupling blasting is commonly used in underground excavation.Determination of perimeter hole parameters(such as the blasthole diameter,spacing,and burden)based on an eccentric charge structure is vital for achieving an excellent smooth blasting effect.In this paper,the Riedel-Hiermaier-Thoma(RHT)model was employed to study rock mass damage under smooth blasting.Firstly,the parameters of the RHT model were calibrated by using the existing SHPB experiment,which were then verified by the existing blasting experiment results.Secondly,the influence of different charge structures on the blasting effect was investigated using the RHT model.The simulation results indicated that eccentric charge blasting has an obvious pressure eccentricity effect.Finally,to improve the blasting effect,the smooth blasting parameters were optimized based on an eccentric charge structure.The overbreak and underbreak phenomena were effectively controlled,and a good blasting effect was achieved with the optimized blasting parameters.
基金supported by National Basic Research Program of China(973 Program,Grant No.2004CCA05700)National Natural Science Foundation of China(Grant No.50875244)Zhejiang Provincial Natural Science Foundation of China(Grant No.Z105706)
文摘The eccentric-gear can be used for variable speed transmission.But,due to the vibrations caused by variation of backlash in working process,the eccentric-gear is seldom applied in engineering project.There is just a little study about the eccentric-gear.And it is necessary to take a further research on eccentric-gear transmission for the applications in the transplanting mechanism of high-speed rice transplanter.The key of this paper is to extend understanding of three following characteristics of this drive:(1)The rotation-center-distance and the geometrical-center-distance of the two meshing eccentric gears are respectively the hypotenuse and the straight edge of a right triangle in a cycle.(2)The geometrical center line of two meshing gears divides the linking-line of the two rotational centers equally.(3)When two times the eccentricity of gear,the rotation-center-distance and the geometrical-center-distance form a right triangle,the optimal value of rotation-center-distance can be determined.In addition,the kinematic analysis,such as the relationship between contact point and midpoint of the linking-line of two gears'rotational centers,transmission ratio between the driving-gear and the driven-gear,contact angle and coordinate of contact point are be made,further the formula for calculation of contact force,flow chart for writing optimization program and curve for analysis of data are also be developed.The relationship between the rotation-center-distance and the geometrical-center-distance,which is determined by three characteristics mentioned above,is a key for the rational design and application of eccentric-gear transmission.Particularly,the presented right triangle property of eccentric gear drive is an important reference for effective analysis of dynamic characteristic of eccentric-gear mechanism and its reliable design.
基金Supported by the Natural Science Foundation of Inner Mongolia (No.200408020715).
文摘The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-maining approximately constant. The experimental results were provided such as the mean velocity field, fluctuat-ing velocities, turbulent kinetic energy, Reynolds shear stress and time series of the velocity in the stirred tank. These results probably provided the valuable basis to further optimize and enlarge the stirred tank in the industrial process.
文摘In this paper, the numerical predictions of 3D hydrodynamics and power consumption in a vessel stirred by mul- tiple eccentrically located impellers are presented. The vessel is a fiat-bottomed cylindrical one equipped with six-curved bladed impellers. Aqueous solutions of xanthan gum are used, which have a shear thinning behavior with yield stress. The influence of several parameters on the mixing efficiency has been investigated, namely： the stirring rate, fluid theology, impeller number and impeller clearance from the tank bottom. Our predicted results are compared with other experimental data and a satisfactory agreement is found.
基金This study was supported by the National Natural Science Foundation of China(No.52074102)Foundation for Distinguished Young Talents in Higher Education of Henan(No.212300410006)+1 种基金Foundation for the Science and Technology Innovation Talents Project of Universities in Henan(No.22HASTIT010)Special Funds for Fundamental Scientific Research Expenses of Universities in Henan(No.NSFRF210202).
文摘The anchoring eccentricity of the bolt and cable bolt is a common problem in geotechnical support engineering and affects the ability of the bolt and cable bolt to control the rock mass to a certain extent.This paper reports on numerical simulation and laboratory experiments conducted to clarify the effect of eccentricity on the anchoring quality of the bolt and cable bolt,and to establish an effective solution strategy.The results reveal that the anchoring eccentricity causes unbalanced stress distribution and the uncoordinated deformation of the resin layer,which results in higher stress and greater deformation of the resin layer at the near side of the rod body.Additionally,as the degree of anchoring eccentricity increases,the effect becomes more significant,and the resin layer of the anchoring system becomes more likely to undergo preferential failure locally,which weakens the load-bearing performance of the anchoring system.This paper develops an innovative bolt anchoring rectifying device(B-ARD)and cable bolt anchoring rectifying device(C-ARD)on the basis of the structural characteristics of the bolt and cable bolt to better ensure the anchoring effect of them.The working effects of these two devices were verified in detailed experiments and analysis.The experimental results show that the anchoring rectifying devices(ARD)improve and ensure the anchoring concentricity of the bolt and cable bolt,which will help improve the supporting performance of them.The paper provides a convenient and effective method for improving the anchoring concentricity of the bolt and cable bolt,and provides a concept and reference for technical research on improving the effect of roof bolting.
基金funded by the Research Council of Norway(Grant No.244029)。
文摘The location and geometry of large-scale asperity present at the foundation of concrete gravity dams and buttress dams affect the shear resistance of the concrete-rock interface.However,the parameters describing the frictional resistance of the interface usually do not account for these asperities.This could result in an underestimate of the peak shear stre ngth,which leads to significantly conservative design for new dams or unnecessary stability enhancing measures for existing ones.The aim of this work was to investigate the effect of the location of first-order asperity on the peak shear strength of a concrete-rock interface under eccentric load and the model discrepancy associated with the commonly used rigid body methods for calculating the factor of safety(FS)against sliding.For this,a series of direct and eccentric shear tests under constant normal load(CNL)was carried out on concrete-rock samples.The peak shear strengths measured in the tests were compared in terms of asperity location and with the predicted values from analytical rigid body methods.The results showed that the large-scale asperity under eccentric load significantly affected the peak shear strength.Furthermore,unlike the conventional assumption of sliding or shear failure of an asperity in direct shear,under the effect of eccentric shear load,a tensile failure in the rock or in the concrete could occur,resulting in a lower shear strength compared with that of direct shear tests.These results could have important implications for assessment of the FS against sliding failure in the concrete-rock interface.
基金Supported in part by Natural Sciences and Engineering Research Council of Canada(NSERC)eMech Systems IncBare Point Water Treatment Plant in Thunder Bay,Ontario,Canada
文摘Induction motors （IMs） are commonly used in various industrial applications. To improve energy con- sumption efficiency, a reliable IM health condition moni- toring system is very useful to detect IM fault at its earliest stage to prevent operation degradation, and malfunction of IMs. An intelligent harmonic synthesis technique is pro- posed in this work to conduct incipient air-gap eccentricity fault detection in IMs. The fault harmonic series are syn- thesized to enhance fault features. Fault related local spectra are processed to derive fault indicators for IM air- gap eccentricity diagnosis. The effectiveness of the pro- posed harmonic synthesis technique is examined experi- mentally by IMs with static air-gap eccentricity and dynamic air-gap eccentricity states under different load conditions. Test results show that the developed harmonic synthesis technique can extract fault features effectively for initial IM air-gap eccentricity fault detection.
基金supported by the National Natural Science Foundation of China(No.50974035)National Natural Science Foundation of China(No.51074047)the doctoral fund of EDU gov(20090407)
文摘In gas injection refining processes, a great amount of gas is injected into molten metal in short time, so that very large bubbles are inevitably formed. Wide dispersion of small bubbles in the bath is indispensable for high refining efficiency. Eccentric mechanical stirring with unidirectional impeller rotation was tested using a water model for pursuing better bubble disintegration and dispersion. Absorption rate are used to research on the influence law of the bubble dispersion and disintegration and gas-liquid absorption by the influence of, rotation mode, rotation speed and gas flow rate. Compared to the experimental results of absorption rate under eccentric stirring and centric stirring ,provide the scientific experimental and theoretical guidance for high-temperature experiment of hot metal desulfurization .According to experimental and theoretical analysis, this paper has studied various factors effecting on gas absorption process and volumetric mass transfer coefficient using the system of CO2-NaOH-H2O.The results show that:the volumetric mass transfer coefficient and absorption efficiency of CO2 can be increased under eccentric stirring mode, Because bubble disperse quickly with eccentric mechanical stirring, which results in promoting complete reaction between CO2 and NaOH, and improving the mass transfer coefficient and absorption. Volumetric mass transfer coefficient and efficiency of CO2 increase with the increasing rotation speed under the condition of eccentric stirring .But volumetric mass transfer coefficient and efficiency of CO2 decrease with the increasing rotation speed under the condition of centric stirring.
基金supported by the National Natural Science Foundation of China(Grant No.51779171)the Tianjin Municipal Natural Science Foundation(Grant No.18JCYBJC22800).
文摘Under the effect of eccentric loads,when the suction pressure of the composite bucket foundation is leveled,the seepage failure is very easy to occur.The seepage failure occurrence causes the foundation to settle unevenly and impairs the bearing performance.This study uses ABAQUS finite element software to establish a composite bucket foundation model for finite element analysis.The model simulates the seepage of the foundation penetrating process under eccentric load to reveal the induced seepage characteristics of the bucket foundation.The most vulnerable position of seepage failure under the eccentric loading is elucidated.Critical suction formulas for different offset eccentric moment strategies are derived and compared with existing literature formulas.Then the derived formula is supplemented and corrected according to the pressure difference between adjacent cabins.Conclusions can be drawn:(1)Under eccentric loads,the critical suction decreases about 7%−10%.(2)The pressure difference between adjacent cabins impacts significantly on the seepage field,and the critical suction,at most,can be reduced by 17.56%.(3)the offset strategies have little effect on the seepage field.Efficient and appropriate strategies can be selected to meet the requirement of leveling in engineering project.
基金supported by the National Natural Science Foundation of China [grant number 11772059]the National KeyResearch and Development Program of China [grant number 2017yfc0822300]+1 种基金the 111 Project[grant number G20012017001]the Foundation of State Key Laboratory of Explosion Science and Technology of China[grant number KFJJ13-1Z]
文摘With the technical development of new warhead designs and improvised explosive device protection,irregular casing filled with explosive has been paid more attention recently. In this paper, we studied the fragmentation of a type of D-shaped casing, which is a common asymmetric casing in the field of warhead design. Based on the radiograph technique, static explosive experiments were conducted with D-shaped casings under four different eccentric initiation ratios to explore their fragmentation. A numerical model was then established to simulate the dynamic response of D-shaped casing filled with explosive. The results of numerical simulation were found to agree well with the experimental data.According to the results of numerical simulation and experimental data, the dynamic responses of Dshaped casing were analyzed. The results of the current work pave way for the innovative design of new warhead and for further studying the dynamic response of asymmetric casing.
基金National Natural Science Foundation of China(No.50875243)
文摘A novel weft insertion mechanism named eccentric conjugate non-circular gear & crank-rocker & gears train weft insertion mechanism was proposed in order to better meet the requirements of rapier loom's weft insertion mechanism as well as reduce the manufacturing difficulty. Meanwhile, based on the working principle of this mechanism, kinematical mathematic models of this mechanism were established and an aided analysis and simulation software was compiled. The influences of eccentricity ratio, deformation coefficient, and other important parameters on the kinematics characteristics of this mechanism were analyzed by using the software. A group of preferable parameters which could meet the requirements of weft insertion technology were obtained by means of human-computer interactive optimization method. The maximum velocity, maximum acceleration, and variation of acceleration of this mechanism are smaller than those of the conjugate cam weft insertion mechanism applied on TT96 rapier loom under the conditions of the same unilateral total stroke of rapier head and the same rotary speed of loom spindle; meanwhile the other demands of weaving technology can be met by this novel weft insertion mechanism.
基金supported by the National Natural Science Foundation of China(22078030,52021004)National Natural Science Foundation of Chongqing(2022NSCQ-LZX0271)+2 种基金Fundamental Research Funds for the Central Universities(2022CDJQY-005)National Key Research and Development Project(2019YFC1905802,2022YFC3901204)Key Project of Independent Research Project of State Key Laboratory of coal mine disaster dynamics and control(2011DA105287-zd201902).
文摘This work aims to systematically study hydrodynamics and mixing characteristics of non-Newtonian fluid(carboxyl methyl cellulose,CMC)in dual shaft eccentric mixer.Fluid rheology was described by the power law rheological model.Computational fluid dynamics was employed to simulate the velocity field and shear rate inside the stirred tank.The influence mechanism of the rotational modes,height difference between impellers,impeller eccentricities,and impeller types on the flow field have been well investigated.We studied the performance of different dual-shaft eccentric mixers at the constant power input with its fluid velocity profiles,average shear strain rate,mixing time and mixing energy.The counter-rotation mode shows better mixing performance than co-rotation mode,and greater eccentricity can shorten mixing time on the basis of same stirred condition.To intensify the hydrodynamic interaction between impellers and enhance the overall mixing performance of the dual shaft eccentric mixers,it is critical to have a reasonable combination of impellers and an appropriate spatial position of impellers.
文摘Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by reduced electromyography signal amplitude,diminished evoked H-reflex responses,increased autogenic MN inhibition,and decreased excitability in descending corticospinal motor pathways.Maximum ECC muscle force recorded during maximal voluntary contraction can be increased by superimposed electrical muscle stimulation only in untrained individuals and not in trained strength athletes,indicating that the suppression in MN activation is modifiable by resistance training.In support of this notion,maximum ECC muscle strength can be increased by use of heavy-load resistance training owing to a removed or diminished suppression in neuromuscular activity.Prolonged(weeks to months)of heavy-load resistance training results in increased H-reflex and V-wave responses during maximal ECC muscle actions along with marked gains in maximal ECC muscle strength,indicating increased excitability of spinal MNs,decreased presynaptic and/or postsynaptic MN inhibition,and elevated descending motor drive.Notably,the use of supramaximal ECC resistance training can lead to selectively elevated V-wave responses during maximal ECC contraction,demonstrating that adaptive changes in spinal circuitry function and/or gains in descending motor drive can be achieved during maximal ECC contraction in response to heavy-load resistance training.
文摘Reinforced concrete(RC)structures are generally designed to carry quasi-static gravity loads through almost indispensable components namely slab,however,it may be subjected to high intense loads induced from the impact of projectiles generated by the tornado,falling construction equipment,and also from accidental explosions during their construction and service lifespan.Impacts due to rock/boulder falls do occur on the structures located especially in hilly areas.Such loadings are not predictable but may cause severe damage to the slab/structure.It stimulates structural engineers and researchers to investigate and understand the dynamic response of RC structures under such impulsive loading.This research work first investigates the performance of 1000×1000×75 mm^(3)conventionally reinforced two-way spanning normal strength concrete slab with only tension reinforcement(0.88%)under the concentric impact load(1035 N)using the finite element method based computer code,ABAQUS/Explicit-v.6.15.The impact load is delivered to the centroid of the slab using a solid-steel cylindroconical impactor(drop weight)with a flat nose of diameter 40 mm,having a total mass of 105 kg released from a fixed height of 2500 mm.Two popular concrete constitutive models in ABAQUS namely;Holmquist-Johnson-Cook(HJC)and Concrete Damage Plasticity(CDP),with strain rate effects as per fib MODEL CODE 2010,are used to model the concrete material behavior to impact loading and to simulate the damage to the slab.The slab response using these two models is analyzed and compared with the impact test results.The strain rate effect on the reinforcing steel bars has been incorporated in the analysis using the Malvar and Crawford(1998)approach.A classical elastoplastic kinematic idealization is considered to model the steel impactor and support system.Results reveal that the HJC model gives a little overestimation of peak displacement,maximum acceleration,and damage of the slab while the predictions given by the CDP model are in reasonable agreement with the experimental test results/observations available in the open literature.Following the validation of the numerical model,analyses have been extended to further investigate the damage response of the slab under eccentric impact loadings.In addition to the concentric location(P1)of the impacting device,five locations on a quarter of the slab i.e.,two along the diagonal(P2&P3),the other two along the mid-span(P4&P5),and the last one(P6)between P3 and P5,covering the entire slab,are considered.Computational results have been discussed and compared,and the evaluation of the most damaging location(s)of the impact is investigated.It has been found that the most critical location of the impact is not the centroid of the slab but the eccentric one with the eccentricity of 1/6th of the span from the centroid along the mid-span section.
