Herein,we reported a copper-catalyzed stereoselective olefinicβ-C(sp^(2))–H imidation of acyclic enamides employing commercially available N-fluorobenzenesulfonimide(NFSI)as an imidating reagent,which allows for the...Herein,we reported a copper-catalyzed stereoselective olefinicβ-C(sp^(2))–H imidation of acyclic enamides employing commercially available N-fluorobenzenesulfonimide(NFSI)as an imidating reagent,which allows for the synthesis of various imidation products with mainly E-selective control.This methodology was featured by being ligand-free,having good efficacy,and exhibiting broad substrate scope for acyclic enamides.Mechanistically,the imidyl radical species might be involved in the reaction.展开更多
The hydrosulfonylation of terminal alkynes employing sulfonohydrazides has been accomplished with cop- per-catalysis in the presence of BPO （benzoic peroxyanhydride）. Generally, excellent yield of the vinyl sulfone ...The hydrosulfonylation of terminal alkynes employing sulfonohydrazides has been accomplished with cop- per-catalysis in the presence of BPO （benzoic peroxyanhydride）. Generally, excellent yield of the vinyl sulfone products has been acquired by heating the reaction at 70℃ in DMSO.展开更多
基金supported by the National Natural Science Foundation of China(22271062)Natural Science Foundation of Jiangxi Province(20242BAB26027).
文摘Herein,we reported a copper-catalyzed stereoselective olefinicβ-C(sp^(2))–H imidation of acyclic enamides employing commercially available N-fluorobenzenesulfonimide(NFSI)as an imidating reagent,which allows for the synthesis of various imidation products with mainly E-selective control.This methodology was featured by being ligand-free,having good efficacy,and exhibiting broad substrate scope for acyclic enamides.Mechanistically,the imidyl radical species might be involved in the reaction.
基金This work is financially supported by the National Natural Science Foundation of China （No. 21562024）.
文摘The hydrosulfonylation of terminal alkynes employing sulfonohydrazides has been accomplished with cop- per-catalysis in the presence of BPO （benzoic peroxyanhydride）. Generally, excellent yield of the vinyl sulfone products has been acquired by heating the reaction at 70℃ in DMSO.
