BACKGROUND Cognitive frailty and depression are prevalent among the elderly,significantly impairing physical and cognitive functions,psychological well-being,and quality of life.Effective interventions are essential t...BACKGROUND Cognitive frailty and depression are prevalent among the elderly,significantly impairing physical and cognitive functions,psychological well-being,and quality of life.Effective interventions are essential to mitigate these adverse effects and enhance overall health outcomes in this population.AIM To evaluate the effects of exercise-cognitive dual-task training on frailty,cognitive function,psychological status,and quality of life in elderly patients with cognitive frailty and depression.METHODS A retrospective study was conducted on 130 patients with cognitive frailty and depression admitted between December 2021 and December 2023.Patients were divided into a control group receiving routine intervention and an observation group undergoing exercise-cognitive dual-task training in addition to routine care.Frailty,cognitive function,balance and gait,psychological status,and quality of life were assessed before and after the intervention.RESULTS After the intervention,the frailty score of the observation group was(5.32±0.69),lower than that of the control group(5.71±0.55).The Montreal cognitive assessment basic scale score in the observation group was(24.06±0.99),higher than the control group(23.43±1.40).The performance oriented mobility assessment score in the observation group was(21.81±1.24),higher than the control group(21.15±1.26).The self-efficacy in the observation group was(28.27±2.66),higher than the control group(30.05±2.66).The anxiety score in the hospital anxiety and depression scale(HADS)for the observation group was(5.86±0.68),lower than the control group(6.21±0.64).The depression score in the HADS for the observation group was(5.67±0.75),lower than the control group(6.27±0.92).Additionally,the scores for each dimension of the 36-item short form survey in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).CONCLUSION Exercise-cognitive dual-task training is beneficial for improving frailty,enhancing cognitive function,and improving psychological status and quality of life in elderly patients with cognitive frailty and depression.展开更多
Emotion recognition plays a crucial role in various fields and is a key task in natural language processing (NLP). The objective is to identify and interpret emotional expressions in text. However, traditional emotion...Emotion recognition plays a crucial role in various fields and is a key task in natural language processing (NLP). The objective is to identify and interpret emotional expressions in text. However, traditional emotion recognition approaches often struggle in few-shot cross-domain scenarios due to their limited capacity to generalize semantic features across different domains. Additionally, these methods face challenges in accurately capturing complex emotional states, particularly those that are subtle or implicit. To overcome these limitations, we introduce a novel approach called Dual-Task Contrastive Meta-Learning (DTCML). This method combines meta-learning and contrastive learning to improve emotion recognition. Meta-learning enhances the model’s ability to generalize to new emotional tasks, while instance contrastive learning further refines the model by distinguishing unique features within each category, enabling it to better differentiate complex emotional expressions. Prototype contrastive learning, in turn, helps the model address the semantic complexity of emotions across different domains, enabling the model to learn fine-grained emotions expression. By leveraging dual tasks, DTCML learns from two domains simultaneously, the model is encouraged to learn more diverse and generalizable emotions features, thereby improving its cross-domain adaptability and robustness, and enhancing its generalization ability. We evaluated the performance of DTCML across four cross-domain settings, and the results show that our method outperforms the best baseline by 5.88%, 12.04%, 8.49%, and 8.40% in terms of accuracy.展开更多
The off situ accurate reconstruction of the core neutron field is an important step in realizing real-time reactor monitoring.The existing off situ reconstruction method of the neutron field is only applicable to case...The off situ accurate reconstruction of the core neutron field is an important step in realizing real-time reactor monitoring.The existing off situ reconstruction method of the neutron field is only applicable to cases wherein a single region changes at a specified location of the core.However,when the neutron field changes are complex,the accurate identification of the individual changed regions becomes challenging,which seriously affects the accuracy and stability of the neutron field recon-struction.Therefore,this study proposed a dual-task hybrid network architecture(DTHNet)for off situ reconstruction of the core neutron field,which trained the outermost assembly reconstruction task and the core reconstruction task jointly such that the former could assist the latter in the reconstruction of the core neutron field under core complex changes.Furthermore,to exploit the characteristics of the ex-core detection signals,this study designed a global-local feature upsampling module that efficiently distributed the ex-core detection signals to each reconstruction unit to improve the accuracy and stability of reconstruction.Reconstruction experiments were performed on the simulation datasets of the CLEAR-I reactor to verify the accuracy and stability of the proposed method.The results showed that when the location uncertainty of a single region did not exceed nine and the number of multiple changed regions did not exceed five.Further,the reconstructed ARD was within 2%,RD_(max)was maintained within 17.5%,and the number of RD≥10%was maintained within 10.Furthermore,when the noise interference of the ex-core detection signals was within±2%,although the average number of RD≥10%increased to 16,the average ARD was still within in 2%,and the average RD_(max)was within 22%.Collectively,these results show that,theoretically,the DTHNet can accurately and stably reconstruct most of the neutron field under certain complex core changes.展开更多
Physical-layer secret key generation(PSKG)provides a lightweight way for group key(GK)sharing between wireless users in large-scale wireless networks.However,most of the existing works in this field consider only grou...Physical-layer secret key generation(PSKG)provides a lightweight way for group key(GK)sharing between wireless users in large-scale wireless networks.However,most of the existing works in this field consider only group communication.For a commonly dual-task scenario,where both GK and pairwise key(PK)are required,traditional methods are less suitable for direct extension.For the first time,we discover a security issue with traditional methods in dual-task scenarios,which has not previously been recognized.We propose an innovative segment-based key generation method to solve this security issue.We do not directly use PK exclusively to negotiate the GK as traditional methods.Instead,we generate GK and PK separately through segmentation which is the first solution to meet dual-task.We also perform security and rate analysis.It is demonstrated that our method is effective in solving this security issue from an information-theoretic perspective.The rate results of simulation are also consistent with the our rate derivation.展开更多
<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ran...<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.展开更多
Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous...Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.展开更多
Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health even...Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.展开更多
Background:This systematic review aimed to examine whether dual-task(DT)training was superior to single-task(ST)training in improving DT walking,balance and cognitive functions for individuals with Parkinson’s diseas...Background:This systematic review aimed to examine whether dual-task(DT)training was superior to single-task(ST)training in improving DT walking,balance and cognitive functions for individuals with Parkinson’s disease(PD).Methods:Literature search was performed in the following electronic databases:PubMed,the Cochrane Library,Web of Science,and Metstr covering inception to May 10,2023.And in order to facilitate comparison across trials,we calculated the effect size(Hedges’g)of gait,balance,cognitive,and other parameters under both ST and DT conditions,using the mean change score and standard deviation(SD)of change score of the experimental and control groups.Randomized controlled trials that examined the effects of DT motor and cognitive training in individuals with Parkinson’s disease were included for this systematic review.Results:A total of 214 participants recruited from six articles(actually five trials)were involved in this review.In terms of walking ability,only double support time and stride time variability showed significant between-group difference(Hedges’g=0.34,0.18,respectively).Compared to ST training group,DT training group had a more improvement effect in laboratory balance measurement(Hedges’g=0.18,1.25),but no significant improvement in clinical balance measurement.No significant between-group differences were observed,thus its training effect on cognitive function was inconclusive.Conclusions:The DT training failed to achieve promising results better than ST training in improving DT walking and balance functions for individuals with PD.Any firm conclusion cannot be drawn at present,due to the limited number of eligible publications.Larger sample size and high-quality studies are needed to investigate the effectiveness of DT training in individuals with PD.展开更多
目的:探讨认知-运动双任务训练对脑卒中患者步行稳定性的影响。方法:计算机检索中国知网、万方数据库、Pubmed、Web of Science、Cochrane library等中英文文献数据库关于认知-运动双任务训练对脑卒中患者步行稳定性影响相关的随机对照...目的:探讨认知-运动双任务训练对脑卒中患者步行稳定性的影响。方法:计算机检索中国知网、万方数据库、Pubmed、Web of Science、Cochrane library等中英文文献数据库关于认知-运动双任务训练对脑卒中患者步行稳定性影响相关的随机对照试验。检索时间为数据库建库至2024年8月20日。由2名研究人员独立对纳入文献进行筛选、数据提取和质量评价。采用Revman5.4软件进行Meta分析。结果:共纳入19篇随机对照试验,共823例患者。Meta分析结果显示,与单任务康复组相比,认知-运动双任务组可改善患者平衡功能[MD=3.94,95%CI(2.84,5.05),P<0.0001]、Fugl-Meyer下肢运动功能评分量表(FMA-LE)评分[MD=2.19,95%CI(0.57,3.81),P=0.008]、单任务步速[MD=0.07,95%CI(0.04,0.09),P<0.0001]、双任务步速[MD=0.12,95%CI(0.09,0.15),P<0.0001]、单任务步长[MD=0.03,95%CI(0.00,0.06),P=0.04]、双任务步长[MD=0.01,95%CI(0.01,0.02),P=0.0008],降低患者跌倒发生率[OR=0.32,95%CI(0.11,0.87),Z=2.24,P=0.03],以上差异均具有统计学意义(P<0.05);2组MMSE量表评分[MD=-0.65,95%CI(-5.82,4.51),P=0.80],差异无统计学意义。结论:认知-运动双任务训练可以有效地改善脑卒中患者单任务步长、双任务步长、单任务步速、双任务步速、平衡功能及FMA-LE评分,并降低跌倒发生率,提升其步态稳定性,但对于认知功能的改善情况尚需更多研究进一步验证。展开更多
文摘BACKGROUND Cognitive frailty and depression are prevalent among the elderly,significantly impairing physical and cognitive functions,psychological well-being,and quality of life.Effective interventions are essential to mitigate these adverse effects and enhance overall health outcomes in this population.AIM To evaluate the effects of exercise-cognitive dual-task training on frailty,cognitive function,psychological status,and quality of life in elderly patients with cognitive frailty and depression.METHODS A retrospective study was conducted on 130 patients with cognitive frailty and depression admitted between December 2021 and December 2023.Patients were divided into a control group receiving routine intervention and an observation group undergoing exercise-cognitive dual-task training in addition to routine care.Frailty,cognitive function,balance and gait,psychological status,and quality of life were assessed before and after the intervention.RESULTS After the intervention,the frailty score of the observation group was(5.32±0.69),lower than that of the control group(5.71±0.55).The Montreal cognitive assessment basic scale score in the observation group was(24.06±0.99),higher than the control group(23.43±1.40).The performance oriented mobility assessment score in the observation group was(21.81±1.24),higher than the control group(21.15±1.26).The self-efficacy in the observation group was(28.27±2.66),higher than the control group(30.05±2.66).The anxiety score in the hospital anxiety and depression scale(HADS)for the observation group was(5.86±0.68),lower than the control group(6.21±0.64).The depression score in the HADS for the observation group was(5.67±0.75),lower than the control group(6.27±0.92).Additionally,the scores for each dimension of the 36-item short form survey in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).CONCLUSION Exercise-cognitive dual-task training is beneficial for improving frailty,enhancing cognitive function,and improving psychological status and quality of life in elderly patients with cognitive frailty and depression.
基金supported by the ScientificResearch and Innovation Team Program of Sichuan University of Science and Technology(No.SUSE652A006)Sichuan Key Provincial Research Base of Intelligent Tourism(ZHYJ22-03)In addition,it is also listed as a project of Sichuan Provincial Science and Technology Programme(2022YFG0028).
文摘Emotion recognition plays a crucial role in various fields and is a key task in natural language processing (NLP). The objective is to identify and interpret emotional expressions in text. However, traditional emotion recognition approaches often struggle in few-shot cross-domain scenarios due to their limited capacity to generalize semantic features across different domains. Additionally, these methods face challenges in accurately capturing complex emotional states, particularly those that are subtle or implicit. To overcome these limitations, we introduce a novel approach called Dual-Task Contrastive Meta-Learning (DTCML). This method combines meta-learning and contrastive learning to improve emotion recognition. Meta-learning enhances the model’s ability to generalize to new emotional tasks, while instance contrastive learning further refines the model by distinguishing unique features within each category, enabling it to better differentiate complex emotional expressions. Prototype contrastive learning, in turn, helps the model address the semantic complexity of emotions across different domains, enabling the model to learn fine-grained emotions expression. By leveraging dual tasks, DTCML learns from two domains simultaneously, the model is encouraged to learn more diverse and generalizable emotions features, thereby improving its cross-domain adaptability and robustness, and enhancing its generalization ability. We evaluated the performance of DTCML across four cross-domain settings, and the results show that our method outperforms the best baseline by 5.88%, 12.04%, 8.49%, and 8.40% in terms of accuracy.
基金supported by the National Natural Science Foundation of China(No.12305344)the 2023 Anhui university research project of China(No.2023AH052179).
文摘The off situ accurate reconstruction of the core neutron field is an important step in realizing real-time reactor monitoring.The existing off situ reconstruction method of the neutron field is only applicable to cases wherein a single region changes at a specified location of the core.However,when the neutron field changes are complex,the accurate identification of the individual changed regions becomes challenging,which seriously affects the accuracy and stability of the neutron field recon-struction.Therefore,this study proposed a dual-task hybrid network architecture(DTHNet)for off situ reconstruction of the core neutron field,which trained the outermost assembly reconstruction task and the core reconstruction task jointly such that the former could assist the latter in the reconstruction of the core neutron field under core complex changes.Furthermore,to exploit the characteristics of the ex-core detection signals,this study designed a global-local feature upsampling module that efficiently distributed the ex-core detection signals to each reconstruction unit to improve the accuracy and stability of reconstruction.Reconstruction experiments were performed on the simulation datasets of the CLEAR-I reactor to verify the accuracy and stability of the proposed method.The results showed that when the location uncertainty of a single region did not exceed nine and the number of multiple changed regions did not exceed five.Further,the reconstructed ARD was within 2%,RD_(max)was maintained within 17.5%,and the number of RD≥10%was maintained within 10.Furthermore,when the noise interference of the ex-core detection signals was within±2%,although the average number of RD≥10%increased to 16,the average ARD was still within in 2%,and the average RD_(max)was within 22%.Collectively,these results show that,theoretically,the DTHNet can accurately and stably reconstruct most of the neutron field under certain complex core changes.
基金supported in part by the National Key R&D Program of China(No.2022YFB2902202)in part by the Fundamental Research Funds for the Central Universities(No.2242023K30034)+2 种基金in part by the National Natural Science Foundation of China(No.62171121,U22A2001),in part by the National Natural Science Foundation of China(No.62301144)in part by the National Natural Science Foundation of Jiangsu Province,China(No.BK20211160)in part by the Southeast University Startup Fund(No.4009012301)。
文摘Physical-layer secret key generation(PSKG)provides a lightweight way for group key(GK)sharing between wireless users in large-scale wireless networks.However,most of the existing works in this field consider only group communication.For a commonly dual-task scenario,where both GK and pairwise key(PK)are required,traditional methods are less suitable for direct extension.For the first time,we discover a security issue with traditional methods in dual-task scenarios,which has not previously been recognized.We propose an innovative segment-based key generation method to solve this security issue.We do not directly use PK exclusively to negotiate the GK as traditional methods.Instead,we generate GK and PK separately through segmentation which is the first solution to meet dual-task.We also perform security and rate analysis.It is demonstrated that our method is effective in solving this security issue from an information-theoretic perspective.The rate results of simulation are also consistent with the our rate derivation.
文摘<strong>Objective</strong>: Purpose of this study was to investigate the behavioral and brain activity impairments in patients after moderate traumatic brain injury (mTBI) in comparison with the normal ranges while dual-tasks performing. We would like to evaluate dual-tasking as diagnostic and rehabilitation tool and to test hypothesis of brain aging after mTBI. <strong>Material and Methods</strong>: Electroencephalographic (EEG), stabilographic and clinical study was performed in 11 patients (mean age 28.8 ± 8.4 years) for up to 1 - 12 months after a mTBI in comparison with 17 healthy subjects (26.7 ± 5.1 years). All the participants performed two motor and two cognitive tasks presented separately, and simultaneously (dual-tasking). <strong>Results</strong>: Clinical examination revealed predominantly cognitive deficit in mTBI patients with intact postural control. EEG data demonstrated coherence decrease for slow (delta-theta) rhythms in frontal-temporal areas predominantly for left hemisphere during cognitive tasks performance. In contrast, EEG coherence for slow spectral bands increased in the same areas in healthy volunteers. EEG coherence increased for fast spectral bands—alpha2 and beta, predominantly in right hemisphere while both healthy adults and patients performed motor components of dual tasks. Rehabilitation course with dual tasks, led to a predominant reduction in cognitive deficits, and EEG coherence increases at the frontal-temporal areas of the left hemisphere. <strong>Conclusions</strong>: Dual-tasks may be used as diagnostic tool in patients after mTBI. This approach demonstrates predominant cognitive deficit, and left hemispheric dysfunction in patients similar to elderly persons and support the hypothesis of brain aging after TBI. Pilot studies also suggested rehabilitation effect of dual-tasking in mTBI patients.
基金the China Postdoctoral Science Foundation,No.2001,#14the Capital Medical Development Science Research Program,No.2005-2003
文摘Stuttering is a common neurological deficit and its underlying cognitive mechanisms are a matter of debate, with evidence suggesting abnormal modulation between speech encoding and other cognitive components. Previous studies have mainly used single task experiments to investigate the disturbance of language production. It is unclear whether there is abnormal interaction between the three language tasks （orthographic, phonological and semantic judgment） in stuttering patients. This study used dual tasks and manipulated the stimulus onset asynchrony （SOA） between tasks 1 and 2 and the nature of the second task, including orthographic, phonological, and semantic judgments. The results showed that the performance records of orthographic judgment, phonological judgment, and semantic judgment were significantly reduced between the patient and control groups with short SOA （P 〈 0.05）. However, different patterns of interaction between task 2 and SOA were observed across subject groups： subjects with stuttering were more strongly modulated by SOA when the second task was semantic judgment or phonological judgment （P 〈 0.05）, but not in the orthographic judgment experiment （P 〉 0.05）. These results indicated that the interaction mechanism between semantic processing and phonological encoding might be an underlying cause for stuttering.
文摘Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.
基金Kunming Health Science and Technology Talent Training Project,Training Plan for Medical Science and Technology Discipline Leaders(No.2022-SW[Leaders]-27)
文摘Background:This systematic review aimed to examine whether dual-task(DT)training was superior to single-task(ST)training in improving DT walking,balance and cognitive functions for individuals with Parkinson’s disease(PD).Methods:Literature search was performed in the following electronic databases:PubMed,the Cochrane Library,Web of Science,and Metstr covering inception to May 10,2023.And in order to facilitate comparison across trials,we calculated the effect size(Hedges’g)of gait,balance,cognitive,and other parameters under both ST and DT conditions,using the mean change score and standard deviation(SD)of change score of the experimental and control groups.Randomized controlled trials that examined the effects of DT motor and cognitive training in individuals with Parkinson’s disease were included for this systematic review.Results:A total of 214 participants recruited from six articles(actually five trials)were involved in this review.In terms of walking ability,only double support time and stride time variability showed significant between-group difference(Hedges’g=0.34,0.18,respectively).Compared to ST training group,DT training group had a more improvement effect in laboratory balance measurement(Hedges’g=0.18,1.25),but no significant improvement in clinical balance measurement.No significant between-group differences were observed,thus its training effect on cognitive function was inconclusive.Conclusions:The DT training failed to achieve promising results better than ST training in improving DT walking and balance functions for individuals with PD.Any firm conclusion cannot be drawn at present,due to the limited number of eligible publications.Larger sample size and high-quality studies are needed to investigate the effectiveness of DT training in individuals with PD.
文摘目的:探讨认知-运动双任务训练对脑卒中患者步行稳定性的影响。方法:计算机检索中国知网、万方数据库、Pubmed、Web of Science、Cochrane library等中英文文献数据库关于认知-运动双任务训练对脑卒中患者步行稳定性影响相关的随机对照试验。检索时间为数据库建库至2024年8月20日。由2名研究人员独立对纳入文献进行筛选、数据提取和质量评价。采用Revman5.4软件进行Meta分析。结果:共纳入19篇随机对照试验,共823例患者。Meta分析结果显示,与单任务康复组相比,认知-运动双任务组可改善患者平衡功能[MD=3.94,95%CI(2.84,5.05),P<0.0001]、Fugl-Meyer下肢运动功能评分量表(FMA-LE)评分[MD=2.19,95%CI(0.57,3.81),P=0.008]、单任务步速[MD=0.07,95%CI(0.04,0.09),P<0.0001]、双任务步速[MD=0.12,95%CI(0.09,0.15),P<0.0001]、单任务步长[MD=0.03,95%CI(0.00,0.06),P=0.04]、双任务步长[MD=0.01,95%CI(0.01,0.02),P=0.0008],降低患者跌倒发生率[OR=0.32,95%CI(0.11,0.87),Z=2.24,P=0.03],以上差异均具有统计学意义(P<0.05);2组MMSE量表评分[MD=-0.65,95%CI(-5.82,4.51),P=0.80],差异无统计学意义。结论:认知-运动双任务训练可以有效地改善脑卒中患者单任务步长、双任务步长、单任务步速、双任务步速、平衡功能及FMA-LE评分,并降低跌倒发生率,提升其步态稳定性,但对于认知功能的改善情况尚需更多研究进一步验证。
