The Boeing 787 Dreamliner,launched in 2011,was presented as a game changer in air travel.With the aim of producing an efficient,mid-size,wide-body plane,Boeing initiated innovations in product and process design,suppl...The Boeing 787 Dreamliner,launched in 2011,was presented as a game changer in air travel.With the aim of producing an efficient,mid-size,wide-body plane,Boeing initiated innovations in product and process design,supply chain operation,and risk management.Nevertheless,there were reliability issues from the start,and the plane was grounded by the U.S.Federal Aviation Administration(FAA)in 2013,due to safety problems associated with Li-ion battery fires.This paper chronicles events associated with the aircraft’s initial reliability challenges.The manufacturing,supply chain,and organizational factors that contributed to these problems are assessed based on FAA data.Recommendations and lessons learned are provided for the benefit of engineers and managers who will be engaged in future complex systems development.展开更多
Nowadays,p53 is like a Dreamliner airplane,riding the high skies of cancer research with dignity and pride.You do not have to be a card-bearing p53 researcher to know about p53,care about it,and respect it.Yet,this wa...Nowadays,p53 is like a Dreamliner airplane,riding the high skies of cancer research with dignity and pride.You do not have to be a card-bearing p53 researcher to know about p53,care about it,and respect it.Yet,this was not always so.As a matter of fact,in the first years of p53 research,from its discovery in the late 1970's to about the end of the 1980's,p53 was more like a kite:one moment high up in the air,the next moment being dragged on the ground.展开更多
文摘The Boeing 787 Dreamliner,launched in 2011,was presented as a game changer in air travel.With the aim of producing an efficient,mid-size,wide-body plane,Boeing initiated innovations in product and process design,supply chain operation,and risk management.Nevertheless,there were reliability issues from the start,and the plane was grounded by the U.S.Federal Aviation Administration(FAA)in 2013,due to safety problems associated with Li-ion battery fires.This paper chronicles events associated with the aircraft’s initial reliability challenges.The manufacturing,supply chain,and organizational factors that contributed to these problems are assessed based on FAA data.Recommendations and lessons learned are provided for the benefit of engineers and managers who will be engaged in future complex systems development.
文摘Nowadays,p53 is like a Dreamliner airplane,riding the high skies of cancer research with dignity and pride.You do not have to be a card-bearing p53 researcher to know about p53,care about it,and respect it.Yet,this was not always so.As a matter of fact,in the first years of p53 research,from its discovery in the late 1970's to about the end of the 1980's,p53 was more like a kite:one moment high up in the air,the next moment being dragged on the ground.
