This is a correction to:Hao Cheng,Jun Yu,Chi Chun Wong,Adenosine-to-inosine RNA editing in cancer:molecular mechanisms and downstream targets,Protein&Cell,2024;https://doi.org/10.1093/procel/pwae039 In the origina...This is a correction to:Hao Cheng,Jun Yu,Chi Chun Wong,Adenosine-to-inosine RNA editing in cancer:molecular mechanisms and downstream targets,Protein&Cell,2024;https://doi.org/10.1093/procel/pwae039 In the originally published version of the manuscript there were errors in Figure 2.In panel H,text should read:"Loses capacity"instead of:"oses capacity";a redundant letter"I"that was highlighted should be removed.展开更多
TNNI3K(troponin-I interacting kinase)encodes a duo tyrosine and serine/threonine kinase implicated in cardiomyopathy,arrhythmias,and cardiac conduction disease(CCD).1 However,no direct downstream phosphorylation targe...TNNI3K(troponin-I interacting kinase)encodes a duo tyrosine and serine/threonine kinase implicated in cardiomyopathy,arrhythmias,and cardiac conduction disease(CCD).1 However,no direct downstream phosphorylation targets of TNNI3K have been identified yet.2 Here,we employed the CRISPR/Cas9 gene-editing technique to generate a splicing mutation in the 4th exon of zebrafish tnni3k ortholog gene that mimics a TNNI3K splicing variant identified from a patient family with cardiomyopathy and CCD.展开更多
文摘This is a correction to:Hao Cheng,Jun Yu,Chi Chun Wong,Adenosine-to-inosine RNA editing in cancer:molecular mechanisms and downstream targets,Protein&Cell,2024;https://doi.org/10.1093/procel/pwae039 In the originally published version of the manuscript there were errors in Figure 2.In panel H,text should read:"Loses capacity"instead of:"oses capacity";a redundant letter"I"that was highlighted should be removed.
基金supported in part by the National Natural Science Foundation of China(No.31970504,31772548,82371863,82070394)the NHC Key Laboratory of Birth Defect for Research and Prevention(Hunan Provincial Maternal and Child Health Care Hospital)(No.KF2021003)the Postgraduate Scientific Innovation Fund of Hunan Province,China(No.CX2018B302).
文摘TNNI3K(troponin-I interacting kinase)encodes a duo tyrosine and serine/threonine kinase implicated in cardiomyopathy,arrhythmias,and cardiac conduction disease(CCD).1 However,no direct downstream phosphorylation targets of TNNI3K have been identified yet.2 Here,we employed the CRISPR/Cas9 gene-editing technique to generate a splicing mutation in the 4th exon of zebrafish tnni3k ortholog gene that mimics a TNNI3K splicing variant identified from a patient family with cardiomyopathy and CCD.
