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Multi-label fundus disease classification using dual-branch deep learning:an intelligent diagnosis framework inspired by traditional Chinese medicine Five Wheels theory
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作者 Xin He Xiaohui Li +5 位作者 Jun Peng Lei Sun Dan Shu Li Xiao Qinghua Peng Xiaoxia Xiao 《Digital Chinese Medicine》 2026年第1期80-90,共11页
Objective To develop a dual-branch deep learning framework for accurate multi-label classification of fundus diseases,addressing the key limitations of insufficient complementary feature extraction and inadequate cros... Objective To develop a dual-branch deep learning framework for accurate multi-label classification of fundus diseases,addressing the key limitations of insufficient complementary feature extraction and inadequate cross-modal feature fusion in existing automated diagnostic methods.Methods The fundus multi-label classification dataset with 12 disease categories(FMLC-12)dataset was constructed by integrating complementary samples from Ocular Disease Intelligent Recognition(ODIR)and Retinal Fundus Multi-Disease Image Dataset(RFMiD),yielding 6936 fundus images across 12 retinal pathology categories,and the framework was validated on both FMLC-12 and ODIR.Inspired by the holistic multi-regional assessment principle of the Five Wheels theory in traditional Chinese medicine(TCM)ophthalmology,the dualbranch multi-label network(DBMNet)was developed as a novel framework integrating complementary visual feature extraction with pathological correlation modeling.The architecture employed a TransNeXt backbone within a dual-branch design:one branch processed redgreen-blue(RGB)images to capture color-dependent features,such as vascular patterns and lesion morphology,while the other processed grayscale-converted images to enhance subtle textural details and contrast variations.A feature interaction module(FIM)effectively integrated the multi-scale features from both branches.Comprehensive ablation studies were conducted to evaluate the contributions of the dual-branch architecture and the FIM.The performance of DBMNet was compared against four state-of-the-art methods,including EfficientNet Ensemble,transfer learning-based convolutional neural network(CNN),BFENet,and EyeDeep-Net,using mean average precision(mAP),F1-score,and Cohen's kappa coefficient.Results The dual-branch architecture improved mAP by 15.44 percentage points over the single-branch TransNeXt baseline,increasing from 34.41%to 44.24%,and the addition of FIM further boosted mAP to 49.85%.On FMLC-12,DBMNet achieved an mAP of 49.85%,a Cohen’s kappa coefficient of 62.14%,and an F1-score of 70.21%.Compared with BFENet(mAP:45.42%,kappa:46.64%,F1-score:71.34%),DBMNet outperformed it by 4.43 percentage points in mAP and 15.50 percentage points in kappa,while BFENet achieved a marginally higher F1-score.On ODIR,DBMNet achieved an F1-score of 85.50%,comparable to state-of-the-art methods.Conclusion DBMNet effectively integrates RGB and grayscale visual modalities through a dual-branch architecture,significantly improving multi-label fundus disease classification.The framework not only addresses the issue of insufficient feature fusion in existing methods but also demonstrates outstanding performance in balancing detection across both common and rare diseases,providing a promising and clinically applicable pathway for standardized,intelligent fundus disease classification. 展开更多
关键词 Multi-label classification Fundus images Deep learning Dual-branch network Traditional Chinese medicine ophthalmology Five Wheels theory
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Single-atom collaboration with cluster for accelerated nitrate electroreduction:Synergy revelation via machine learning and DFT calculations
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作者 Ruochen Zhu Haoyu Wang +4 位作者 Kongke Tang Xinyuan Yang Xiuxian Zhao Jiayuan Yu Riming Hu 《Journal of Energy Chemistry》 2026年第1期842-851,I0019,共11页
Exploring high-performance electrocatalysts for the nitrate reduction reaction(NO_(3)RR)is crucial for environmental nitrate removal and ammonia synthesis.Single-atom collaboration with cluster can provide sufficient ... Exploring high-performance electrocatalysts for the nitrate reduction reaction(NO_(3)RR)is crucial for environmental nitrate removal and ammonia synthesis.Single-atom collaboration with cluster can provide sufficient active sites for catalysts to promote NO_(3)RR,yet the unclear synergistic effect between the two hinders their rational design.Herein,a series of Ir_(3)clusters and metal single atoms co-embedded in graphitic carbon nitride(g-CN)catalysts(Ir_(3)M1)were constructed,and the synergistic effects of Ir_(3)clusters and M1 single atoms on the NO_(3)RR catalytic mechanism and activity were systematically explored using density functional theory(DFT)calculations combined with machine learning.Comprehensive evaluations of structural stability and catalytic activity demonstrate that the synergy between single atoms and clusters effectively balances the adsorption energies of key intermediates,yielding exceptional catalytic performance(the limiting potential of Ir_(3)Ti_(1)can reach−0.22 V).Machine learning models further clarify the synergistic mechanism,where the geometric configurations of clusters serve as critical features for modulating the catalytic activity of single-atom sites,whereas the electronic structures of single atoms directly govern the reactivity of cluster sites.This DFT-machine learning approach provides theoretical guidelines for catalyst design and a predictive framework for efficient NO_(3)RR electrocatalysts. 展开更多
关键词 Nitrate reduction reaction Density functional theory Single-atom catalysts CLUSTER Machine learning
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Promoting psychological well-being in AI-enhanced english as a foreign language learning:A mixed-methods study of motivation,language learning anxiety and trust in higher education
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作者 Zhiyong Sun 《Journal of Psychology in Africa》 2026年第1期33-43,共11页
This mixed-methods study investigated how AI-enhanced English as a Foreign Language(EFL)learning environments influence students’psychological well-being through the mediating roles of motivation and language learnin... This mixed-methods study investigated how AI-enhanced English as a Foreign Language(EFL)learning environments influence students’psychological well-being through the mediating roles of motivation and language learning anxiety and the moderating role of trust.Participants were Chinese university students(N=310,62%female,mean age=18.9,SD=0.8),of whom 15 completed interviews to both add to and to clarify the evidence from the surveys.Structural equation modeling results revealed that AI use had significant indirect effects on well-being through increased motivation and reduced language learning anxiety.Trust in AI significantly moderated both paths,amplifying the motivational benefits and anxiety reduction associated with AI use.Thematic analysis supported these results,identifying three experiential themes:(1)motivational empowerment through personalization,(2)anxiety regulation through safe practice and feedback,and(3)trust as the emotional bridge between AI and well-being.The study extends AI psychology applications by empirically linking technology engagement with affective outcomes and underscores the need for human-centered and trust-enhancing design in AI-supported education.From these findings,we conclude that adaptive,transparent,and autonomy-supportive AI systems promote self-determined motivation,emotional safety,and overall psychological health among EFL learners. 展开更多
关键词 Artificial intelligence psychology EFL learning MOTIVATION anxiety trust WELL-BEING mixed methods self-determination theory
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Synergistic machine learning and DFT screening strategy:Accelerating discovery of efficient perovskite passivators
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作者 Jianghao Liu Hongyan Lv +4 位作者 Pengyang Wang Guofu Hou Ying Zhao Xiaodan Zhang Qian Huang 《Journal of Energy Chemistry》 2026年第1期56-63,I0003,共9页
Efficient surface passivation is critical for achieving high-performance perovskite solar cells(PSCs),yet the discovery of optimal passivators remains a time-consuming,trial-and-error process.Here,we report a synergis... Efficient surface passivation is critical for achieving high-performance perovskite solar cells(PSCs),yet the discovery of optimal passivators remains a time-consuming,trial-and-error process.Here,we report a synergistic machine learning(ML)and density functional theory(DFT)approach that enables predictive and rapid identification of effective passivation materials.By training an XGBoost model(91.3%accuracy)with DFT-derived molecular descriptors and activity calculations,we identify 2-(4-aminophenyl)-3H-benzimidazol-5-amine(APBIA)as a promising passivator.Experimental validation demonstrates that APBIA effectively removes surface impurities and passivates defects within perovskite films,leading to a significant increase in power conversion efficiency(PCE)from 22.48%to 25.55%(certified as 25.02%).This ML-DFT framework provides a generalizable pathway for accelerating the development of advanced functional materials for photovoltaic applications. 展开更多
关键词 Perovskite solar cells Machine learning(ML) Density functional theory(DFT) Passivators Organic molecule
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Modeling the Influencing Factors of EFL Learners’ Online Interactive Learning: A Grounded Theory Approach
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作者 Guihua Ma 《Chinese Journal of Applied Linguistics》 2025年第3期401-424,481,共25页
Online interactive learning plays a crucial role in improving online education quality.This grounded theory study examines:(1)what key factors shape EFL learners’online interactive learning,(2)how these factors form ... Online interactive learning plays a crucial role in improving online education quality.This grounded theory study examines:(1)what key factors shape EFL learners’online interactive learning,(2)how these factors form an empirically validated model,and(3)how they interact within this model,through systematic analysis of 9,207 discussion forum posts from a Chinese University MOOC platform.Results demonstrate that learning drive,course structure,teaching competence,interaction behavior,expected outcomes,and online learning context significantly influence EFL online interactive learning.The analysis reveals two key mechanisms:expected outcomes mediate the effects of learning drive(β=0.45),course structure,teaching competence,and interaction behavior(β=0.35)on learning outcomes,while online learning context moderates these relationships(β=0.25).Specifically,learning drive provides intrinsic/extrinsic motivation,whereas course structure,teaching competence,interaction behavior,and expected outcomes collectively enhance interaction quality and sustainability.These findings,derived through rigorous grounded theory methodology involving open,axial,and selective coding of large-scale interaction data,yield three key contributions:(1)a comprehensive theoretical model of EFL online learning dynamics,(2)empirical validation of mediation/moderation mechanisms,and(3)practical strategies for designing scaffolded interaction protocols and adaptive feedback systems.The study establishes that its theoretically saturated model(achieved after analyzing 7,366 posts with 1,841 verification cases)offers educators evidence-based approaches to optimize collaborative interaction in digital EFL environments. 展开更多
关键词 online learning EFL learners interactive learning influencing factors grounded theory approach
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Rapid Discovery of Gas Response in Materials Via Density Functional Theory and Machine Learning
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作者 Shasha Gao Yongchao Cheng +1 位作者 Lu Chen Sheng Huang 《Energy & Environmental Materials》 2025年第1期164-172,共9页
In this study,a framework for predicting the gas-sensitive properties of gas-sensitive materials by combining machine learning and density functional theory(DFT)has been proposed.The framework rapidly predicts the gas... In this study,a framework for predicting the gas-sensitive properties of gas-sensitive materials by combining machine learning and density functional theory(DFT)has been proposed.The framework rapidly predicts the gas response of materials by establishing relationships between multisource physical parameters and gas-sensitive properties.In order to prove its effectiveness,the perovskite Cs_(3)Cu_(2)I_(5) has been selected as the representative material.The physical parameters before and after the adsorption of various gases have been calculated using DFT,and then a machine learning model has been trained based on these parameters.Previous studies have shown that a single physical parameter alone is not enough to accurately predict the gas sensitivity of materials.Therefore,a variety of physical parameters have been selected for machine learning,and the final machine learning model achieved 92%accuracy in predicting gas sensitivity.It is important to note that although there have been no previous reports on the response of Cs_(3)Cu_(2)I_(5) to hydrogen sulfide,the resulting model predicts the gas response of H2S;it is subsequently confirmed experimentally.This method not only enhances the understanding of the gas sensing mechanism,but also has a universal nature,making it suitable for the development of various new gas-sensitive materials. 展开更多
关键词 density functional theory gas-sensitive materials machine learning
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Application of Situational Cognitive Learning Theory in College English Teaching
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作者 Hui Zhang 《Journal of Contemporary Educational Research》 2025年第2期78-83,共6页
College English teaching is a crucial component of higher education.Enhancing college students’English learning outcomes has long been a primary focus for educators.With the continuous evolution of educational philos... College English teaching is a crucial component of higher education.Enhancing college students’English learning outcomes has long been a primary focus for educators.With the continuous evolution of educational philosophies,traditional college English teaching methods no longer meet the learning needs of contemporary students.Situational cognitive learning theory emphasizes learner-centered approaches and highlights the contextual and practical application of knowledge,offering innovative perspectives for reforming college English teaching.When applied effectively,situational cognitive learning theory can optimize teaching methods and significantly improve learning outcomes.This paper explores the connotation and characteristics of situational cognitive learning theory,evaluates its applicability in college English teaching,and discusses its practical implementation in this context.The aim is to provide theoretical and practical references for improving the quality of college English education. 展开更多
关键词 Situational cognitive learning theory College English Teaching application
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Designing a Health Education Card Game for Adolescents Based on Constructivist Learning Theory:A Case Study of“Night of Hospital”
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作者 You Zhou 《Journal of Contemporary Educational Research》 2025年第6期257-263,共7页
This study explores the design of functional health science games from the perspective of constructivist learning theory,with a particular focus on card-based gameplay.Using antibiotic-resistant bacteria and phage the... This study explores the design of functional health science games from the perspective of constructivist learning theory,with a particular focus on card-based gameplay.Using antibiotic-resistant bacteria and phage therapy as thematic content,the research proposes three core design principles:interactive exploratory environments,progressively challenging yet controllable level structures,and trial-and-error-based learning.These principles are applied in the prototype game Night of Hospital.The study details the design process across three key dimensions—visual environment,level mechanics,and deck-building systems—and demonstrates how knowledge construction can be embedded within the game system.The findings provide a viable framework for enhancing both the educational impact and entertainment value of science communication games. 展开更多
关键词 Constructivist learning theory Health science communication Card game design
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Project-based Language Learning: an Activity Theory Analysis in SOE Language Learning
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作者 陈苡晴 《海外英语》 2016年第10期215-217,220,共4页
This study focuses on the effectiveness of the project-based language learning(PBLL) in a college Secretarial Oral English(SOE) Module. Student reflections of the language project work have been analyzed through Activ... This study focuses on the effectiveness of the project-based language learning(PBLL) in a college Secretarial Oral English(SOE) Module. Student reflections of the language project work have been analyzed through Activity Theory. Moreover,Data has been collected and categorized based on the components of complex human activity: the subject, object, tools(signs,symbols, and language), the community in which the activity take place, division of labor, and rules. The findings theoretically support the outcome of project-based language learning which align with the object of the activity. 展开更多
关键词 ACTIVITY theory PROJECT-BASED learning SOE LANGUAGE learning
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College English Teaching Study Conducted by Discovery Learning Theory and Action Research——Take College English Ⅱ for Instance
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作者 李姝颖 《海外英语》 2017年第4期221-222,共2页
The unceasing revolution of the global economy and culture boosts the revolutionary step of the educational circle.Combining the creed of The Guide of College English Teaching in 2016 with the results of investigation... The unceasing revolution of the global economy and culture boosts the revolutionary step of the educational circle.Combining the creed of The Guide of College English Teaching in 2016 with the results of investigation and survey in colleges, a research group in the Institute of Foreign Languages of Hankou University comes up with a revolutionary trial scheme on College English teaching conducted by discovery learning theory, as well as a research method of action research, which is in hope of mending the problems and shortcomings of current College English teaching. 展开更多
关键词 college English discovery learning theory action research teaching revolution
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Applying Learning Community Theory to Oral English Teaching in Sport Institutes
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作者 杭花平 《海外英语》 2017年第19期236-237,共2页
Since traditional English teaching method, which merely focuses on language teaching but ignores communicative competence, severely impedes the development of students' oral ability. It is high time that English t... Since traditional English teaching method, which merely focuses on language teaching but ignores communicative competence, severely impedes the development of students' oral ability. It is high time that English teachers took measures to find a workable and valuable teaching method which can improve students' speaking proficiency effectively. Learning community theory provides a broad space for this, for it regards learning as a process which takes place in a community where the learners are sharing their experience towards knowledge building in an interactive and cooperative way. 展开更多
关键词 learning community theory oral English teaching sport institutes
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The Application of Constructivism Theory to the Student-determined College English Learning 被引量:3
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作者 罗丹丹 《Sino-US English Teaching》 2006年第6期33-35,共3页
According to the further exploration into constructivism theory, the author illustrates the application of this theory to China's college English teaching, especially in the new perspective of student-determined lear... According to the further exploration into constructivism theory, the author illustrates the application of this theory to China's college English teaching, especially in the new perspective of student-determined learning. 展开更多
关键词 constructivism theory student-determined learning INSTRUCTION
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A Summary of Some Teaching Methodologies as well as Some Linguistic and Learning Theories
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作者 秦耀咏 《玉林师范学院学报》 2003年第2期99-105,共7页
This paper tries to summarize some main schools 0f teaching methodologies abroad and some main learning theories abroad. From this paper, we can know the main learning theories, the basic theories of them and the lead... This paper tries to summarize some main schools 0f teaching methodologies abroad and some main learning theories abroad. From this paper, we can know the main learning theories, the basic theories of them and the leading figures. It can help us understand the characteristics of each school of the teaching methodologies and learning theories. 展开更多
关键词 英语教学 教学方法论 学习理论 语言学
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Primordial hydrogen partitioning at Earth’s core-mantle boundary:Multicomponent effects revealed by machine learning-augmented first-principles simulations 被引量:1
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作者 ZePing Jiang YuYang He ZhiGang Zhang 《Earth and Planetary Physics》 2025年第5期1001-1009,共9页
Hydrogen partitioning between liquid iron alloys and silicate melts governs its distribution and cycling in Earth’s deep interior.Existing models based on simplified Fe-H systems predict strong hydrogen sequestration... Hydrogen partitioning between liquid iron alloys and silicate melts governs its distribution and cycling in Earth’s deep interior.Existing models based on simplified Fe-H systems predict strong hydrogen sequestration into the core.However,these models do not account for the modulating effects of major light elements such as oxygen and silicon in the core during Earth’s primordial differentiation.In this study,we use first-principles molecular dynamics simulations,augmented by machine learning techniques,to quantify hydrogen chemical potentials in quaternary Fe-O-Si-H systems under early core-mantle boundary conditions(135 GPa,5000 K).Our results demonstrate that the presence of 5.2 wt%oxygen and 4.8 wt%silicon reduces the siderophile affinity of hydrogen by 35%,decreasing its alloy-silicate partition coefficient from 18.2(in the case of Fe-H)to 11.8(in the case of Fe-O-Si-H).These findings suggest that previous estimates of the core hydrogen content derived from binary system models require downward revision.Our study underscores the critical role of multicomponent interactions in core formation models and provides first-principles-derived constraints to reconcile Earth’s present-day hydrogen reservoirs with its accretionary history. 展开更多
关键词 partition coefficient HYDROGEN core-mantle differentiation light elements machine learning density functional theory
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Hybrid data-driven framework for shale gas production performance analysis via game theory, machine learning, and optimization approaches 被引量:3
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作者 Jin Meng Yu-Jie Zhou +4 位作者 Tian-Rui Ye Yi-Tian Xiao Ya-Qiu Lu Ai-Wei Zheng Bang Liang 《Petroleum Science》 SCIE EI CAS CSCD 2023年第1期277-294,共18页
A comprehensive and precise analysis of shale gas production performance is crucial for evaluating resource potential,designing a field development plan,and making investment decisions.However,quantitative analysis ca... A comprehensive and precise analysis of shale gas production performance is crucial for evaluating resource potential,designing a field development plan,and making investment decisions.However,quantitative analysis can be challenging because production performance is dominated by the complex interaction among a series of geological and engineering factors.In fact,each factor can be viewed as a player who makes cooperative contributions to the production payoff within the constraints of physical laws and models.Inspired by the idea,we propose a hybrid data-driven analysis framework in this study,where the contributions of dominant factors are quantitatively evaluated,the productions are precisely forecasted,and the development optimization suggestions are comprehensively generated.More specifically,game theory and machine learning models are coupled to determine the dominating geological and engineering factors.The Shapley value with definite physical meaning is employed to quantitatively measure the effects of individual factors.A multi-model-fused stacked model is trained for production forecast,which provides the basis for derivative-free optimization algorithms to optimize the development plan.The complete workflow is validated with actual production data collected from the Fuling shale gas field,Sichuan Basin,China.The validation results show that the proposed procedure can draw rigorous conclusions with quantified evidence and thereby provide specific and reliable suggestions for development plan optimization.Comparing with traditional and experience-based approaches,the hybrid data-driven procedure is advanced in terms of both efficiency and accuracy. 展开更多
关键词 Shale gas Production performance DATA-DRIVEN Dominant factors Game theory Machine learning Derivative-free optimization
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Item Response Theory Based Ensemble in Machine Learning 被引量:2
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作者 Ziheng Chen Hongshik Ahn 《International Journal of Automation and computing》 EI CSCD 2020年第5期621-636,共16页
In this article,we propose a novel probabilistic framework to improve the accuracy of a weighted majority voting algorithm.In order to assign higher weights to the classifiers which can correctly classify hard-to-clas... In this article,we propose a novel probabilistic framework to improve the accuracy of a weighted majority voting algorithm.In order to assign higher weights to the classifiers which can correctly classify hard-to-classify instances,we introduce the item response theory(IRT)framework to evaluate the samples′difficulty and classifiers′ability simultaneously.We assigned the weights to classifiers based on their abilities.Three models are created with different assumptions suitable for different cases.When making an inference,we keep a balance between the accuracy and complexity.In our experiment,all the base models are constructed by single trees via bootstrap.To explain the models,we illustrate how the IRT ensemble model constructs the classifying boundary.We also compare their performance with other widely used methods and show that our model performs well on 19 datasets. 展开更多
关键词 CLASSIFICATION ensemble learning item response theory machine learning expectation maximization(EM)algorithm
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Anderson's Cognitive Theory and Learning Strategy Studies in Second Language Acquisition 被引量:9
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作者 Lu Wenpeng (Foreign Languages department, Northwest Normal University, Lanzhou, 730070, China) 《兰州大学学报(社会科学版)》 CSSCI 北大核心 2000年第S1期228-231,共4页
Second language acquisition can not be understood without addressing the interaction between language and cognition. Cognitive theory can extend to describe learning strategies as complex cognitive skills. Theoretical... Second language acquisition can not be understood without addressing the interaction between language and cognition. Cognitive theory can extend to describe learning strategies as complex cognitive skills. Theoretical developments in Anderson’s production systems cover a broader range of behavior than other theories, including comprehension and production of oral and written texts as well as comprehension, problem solving, and verbal learning.Thus Anderson’s cognitive theory can be served as a rationale for learning strategy studies in second language acquisition. 展开更多
关键词 Anderson’s cognitive theory Anderson’s production systems learning strategy studies second language acquisition
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Recognition and interfere deceptive behavior based on inverse reinforcement learning and game theory 被引量:2
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作者 ZENG Yunxiu XU Kai 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2023年第2期270-288,共19页
In real-time strategy(RTS)games,the ability of recognizing other players’goals is important for creating artifical intelligence(AI)players.However,most current goal recognition methods do not take the player’s decep... In real-time strategy(RTS)games,the ability of recognizing other players’goals is important for creating artifical intelligence(AI)players.However,most current goal recognition methods do not take the player’s deceptive behavior into account which often occurs in RTS game scenarios,resulting in poor recognition results.In order to solve this problem,this paper proposes goal recognition for deceptive agent,which is an extended goal recognition method applying the deductive reason method(from general to special)to model the deceptive agent’s behavioral strategy.First of all,the general deceptive behavior model is proposed to abstract features of deception,and then these features are applied to construct a behavior strategy that best matches the deceiver’s historical behavior data by the inverse reinforcement learning(IRL)method.Final,to interfere with the deceptive behavior implementation,we construct a game model to describe the confrontation scenario and the most effective interference measures. 展开更多
关键词 deceptive path planning inverse reinforcement learning(IRL) game theory goal recognition
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