The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organiza...The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organizations and people does it refer to?How can be"earnest"?These questions are worth the contemplation of people like us who are performing China’s public diplomacy.展开更多
Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant ad...Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant advantages of GAs,including improved clarity,increased reader engagement,and enhanced visibility of research findings.By transforming intricate scientific data into accessible visual formats,these abstracts facilitate quick and effective knowledge transfer,crucial in clinical decision-making and patient care.However,challenges such as potential data misrepresentation due to oversimplification,the skill gap in graphic design among researchers,and the lack of standardized creation guidelines pose barriers to their widespread adoption.Additionally,while software such as Adobe Illustrator,BioRender,and Canva are commonly employed to create these visuals,not all researchers may be proficient in their use.To address these issues,we recommend that academic journals establish clear guidelines and provide necessary design training to researchers.This proactive approach will ensure the creation of high-quality GAs,promote their standardization,and expand their use in clinical reporting,ultimately benefiting the medical community and improving healthcare outcomes.展开更多
This paper is focused on discussing the case of Las Loras UNESCO Global Geopark,in Spain,as an example to show the contribution of Geoparks to the dissemination of science and the relevance of preserving geoheritage b...This paper is focused on discussing the case of Las Loras UNESCO Global Geopark,in Spain,as an example to show the contribution of Geoparks to the dissemination of science and the relevance of preserving geoheritage by implementing simple measures based on communication and prevention.Natural and anthropic hazards derived from climate change are endangering heritage and the well-ness of the society.Geoheritage is vulnerable.Nowadays we are witnessing the destruction of monuments with high emotional significance due to wars,but climate change is also contributing to the loss of the same cultural heritage.Prevention is often the best way to protect geoheritage from disappearing and society is the best agent to implement preventive measures.Citizens are often unaware of the important treasures they have around them.Geoparks have been a great tool to bring awareness in society,since by involving the public in the whole process of recognition and promotion,they protect the space and the cultural and economic values associated with them.It is important to communicate the initiatives taking place in the Geoparks to explain the importance of geology and the risk of losing the geoheritage if natural hazards increase.Las Loras study is a good practice to implement in other Geoparks.展开更多
One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces th...One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces the mosquito’s ability to transmit dengue through reproductive strategies associated with Wolbachia infection, such as parthenogenesis, male elimination or feminization, sex ratio distortions and cytoplasmic incompatibility. Expert knowledge and a risk assessment framework were used to identify the risks associated with the release of Wolbachia-bearing mosquitoes. Then, consultations with individual participants were organized and a Bayesian network (BN) was developed to capture the relationship between the hazards as well as the likelihood of these adverse events occurring. Finally, risk was calculated from the probability and consequence estimates obtained from our Burkina Faso participants, using a questionnaire based on the identified risks. Our “Cause More Harm” study yielded 46.15% negligible risk, 44.23% very low risk and 9.62% low risk. The “socio-cultural change” parameter had the greatest influence, with the perception that the dissemination project would be poorly received by the local population. This parameter alone accounted for 80% of the most significant risks. This explains the fact that hazard RA 49 “negative messages in social media” is ranked as the highest individual risk (although the risk is low) with a calculated risk of 0.261. The risk assessment was designed to integrate the interdependent complexity of hazards likely to affect the dissemination of technology in the environment. It represents an important implementation phase in the success of this innovative research, introducing a new technology to combat the transmission of dengue fever.展开更多
BACKGROUND Erythrodermic psoriasis(EP)is a rare and life-threatening form of psoriasis associated with significant morbidity and mortality.Systemic immunosuppre-ssive therapies are often required but may predispose to...BACKGROUND Erythrodermic psoriasis(EP)is a rare and life-threatening form of psoriasis associated with significant morbidity and mortality.Systemic immunosuppre-ssive therapies are often required but may predispose to opportunistic infections.Disseminated herpes simplex virus type-1(HSV-1)is an unusual complication in otherwise immunocompetent patients and has not been reported in association with ixekizumab therapy for EP.CASE SUMMARY We describe a 49-year-old man with longstanding severe plaque psoriasis,liver cirrhosis,and bipolar disorder who developed EP involving>90%of body surface area[Psoriasis Area and Severity Index(PASI)45].Following initial stabil-ization,he was admitted to the intensive care unit(ICU)with hemodynamic instability,leukocytosis with eosinophilia,and diffuse desquamation.Ixekizumab was initiated with high-dose topical clobetasol.During his ICU stay,he developed recurrent bacteremias and neurologic decline(Glasgow Coma Scale 7/15),fo-llowed by the appearance of widespread vesicles and hemorrhagic crusts.HSV-1 infection was confirmed by polymerase chain reaction(PCR).Immunosuppressive therapy was withheld,and intravenous acyclovir was started,leading to progre-ssive improvement.After ten days,ixekizumab was reintroduced with careful monitoring,resulting in marked clinical improvement(PASI 9.7 at six weeks).The patient remained stable on long-term follow-up with oral acyclovir prophylaxis.CONCLUSION This case highlights the diagnostic and therapeutic challenges of managing EP in the setting of biologic therapy.Disseminated cutaneous HSV-1 should be considered in immunosuppressed patients presenting with new vesicular eruptions,and prompt PCR testing with early antiviral therapy is essential.A multidisciplinary approach is critical to balance immunosuppression for disease control with infection risk.展开更多
In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans...In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans-lational Neuroscience.The author(s)shall grant the fol-lowing worldwide exclusive rights carried by the said article in different languages to Journal of Translational Neuroscience free of charge:reproductions,distribution,electronic dissemination,translation and compilation.The author(s)authorize(s)Journal of Translational Neu-roscience to register the said article(including all the in-termedia)with the proper copyright authorities.展开更多
Transactions of Nanjing University of Acronautics&Astronautics(TNUAA)is a bimonthly joumnal facing intermational academic community.Emphasizing prompt and efective dissemination of key data and new scientific insi...Transactions of Nanjing University of Acronautics&Astronautics(TNUAA)is a bimonthly joumnal facing intermational academic community.Emphasizing prompt and efective dissemination of key data and new scientific insights,TNUAA publishes experimental and theoretical papers bearing on applications to all branches of aeronautics,astronautics and civill aviation.展开更多
BACKGROUND Histoplasmosis is a rare infectious condition with mainly pulmonary involvement which is generally self-limiting in immunocompetent individuals.Its manifestation varies and lacks specificity.This study repo...BACKGROUND Histoplasmosis is a rare infectious condition with mainly pulmonary involvement which is generally self-limiting in immunocompetent individuals.Its manifestation varies and lacks specificity.This study reports a case of primary disseminated liver histoplasmosis in a normal host presenting as liver failure cured by liver transplantation and voriconazole.CASE SUMMARY A 43-year-old Chinese man with intermittent fever,malaise,jaundice and extreme hepatomegaly for more than 40 days was admitted to the Second Xiang-ya Hospital.The patient was immunocompetent and lacked a definitive history of exposure.His condition deteriorated to liver failure,and he promptly underwent liver transplantation to ensure survival.One year later,the patient presented with severe gastrointestinal symptoms,including fever,abdominal pain,and diarrhea.Subsequently,tissue samples acquired via gastrointestinal endoscopy were subjected to pathological examination and next-generation sequencing analysis.Through a comprehensive amalgamation of clinical presentation,biopsy pathology,and next-generation sequencing analysis,the patient was ultimately diagnosed with disseminated hepatic histoplasmosis.The patient achieved complete recovery after 6 months of voriconazole treatment.CONCLUSION In patients with chronic-hepatitis-B having atypical symptoms,histoplasmosis can be a differential diagnosis.Voriconazole is effective in treating histoplasmosis.展开更多
Rationale:Melioidosis is a serious opportunistic infection caused by Burkholderia(B.)pseudomallei,primarily affecting immunocompromised individuals,particularly in endemic regions.Timely diagnosis and appropriate trea...Rationale:Melioidosis is a serious opportunistic infection caused by Burkholderia(B.)pseudomallei,primarily affecting immunocompromised individuals,particularly in endemic regions.Timely diagnosis and appropriate treatment are crucial to prevent fatal outcomes.Patient concerns:Case 1 was a 34-year-old male kidney transplant recipient who presented with a 15-day history of intermittent fever,accompanied by liver and spleen abscesses.Case 2 was a 37-year-old female kidney transplant recipient who presented with acute febrile illness and developed leucopenia.Blood cultures for both patients grew B.pseudomallei.Diagnosis:Both patients were diagnosed with melioidosis caused by B.pseudomallei,with the diagnosis confirmed through pus culture from the liver abscess in Case 1 and blood culture in Case 2.Interventions:Both patients were treated with an intensive regimen of meropenem(renal-adjusted doses),followed by a 3-month course of oral cotrimoxazole for eradication therapy.Outcomes:Case 1 experienced resolution of liver and spleen abscesses after 3 months of treatment and continued to recover well.In Case 2,blood cultures became sterile after 4 weeks,with no further complications observed.Lessons:Melioidosis should be suspected in immunocompromised patients,especially kidney transplant recipients,who present with unexplained fever and sepsis-like symptoms.Early diagnosis through aspiration of abscesses and prompt treatment are critical for preventing relapses and improving patient outcomes.展开更多
In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met...In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.展开更多
BACKGROUND Atopic dermatitis(AD),or eczema,is a chronic,pruritic inflammatory skin disease affecting children and adults.Socioeconomic status(SES)plays a significant role in developing AD.However,mixed evidence from a...BACKGROUND Atopic dermatitis(AD),or eczema,is a chronic,pruritic inflammatory skin disease affecting children and adults.Socioeconomic status(SES)plays a significant role in developing AD.However,mixed evidence from a previous study by Bajwa et al makes it difficult to determine the directionality of the association.There is a lite-rature gap in understanding the causal association between AD and socioeco-nomic factors.AIM To evaluate the impact of disparities in SES on pediatric AD populations.METHODS Based on the eligibility criteria,the literature review identified eight articles since July 2021,and a descriptive analysis was conducted using an Excel spreadsheet on key components collected from the identified studies.RESULTS Eight observational studies assessed SES in pediatric AD.Five observational studies showed mixed associations between AD and SES.Sub-analysis revealed that urban areas had a higher prevalence of AD,and four studies identified a positive association between parental education and AD in the pediatric popu-lation.Socioeconomic variables,such as residential areas and household income,significantly influence disease outcomes.CONCLUSION There is mixed association between pediatric AD and SES,with AD positively associated with parental education.There is critical need to evaluate global impact of SES variables on pediatric AD.展开更多
The application of short videos in agricultural scenarios has become a new form of productive force driving agricultural development,injecting new vitality and opportunities into traditional agriculture.These videos l...The application of short videos in agricultural scenarios has become a new form of productive force driving agricultural development,injecting new vitality and opportunities into traditional agriculture.These videos leverage the unique expressive logic of the platform by adopting a small entry point and prioritizing dissemination rate.They are strategically planned in terms of content,visuals,and interaction to cater to users needs for relaxation,knowledge acquisition,social sharing,agricultural product marketing,and talent display.Through careful design,full creativity,rich emotion,and the creation of distinct character personalities,these videos deliver positive,entertaining,informative,and opinion-driven agricultural content.The production and operation of agricultural short videos can be effectively optimized by analyzing the characteristics of both popular and less popular videos,and utilizing smart tools and trending topics.展开更多
As the economy grows, environmental issues are becoming increasingly severe, making the promotion of green behavior more urgent. Information dissemination and policy regulation play crucial roles in influencing and am...As the economy grows, environmental issues are becoming increasingly severe, making the promotion of green behavior more urgent. Information dissemination and policy regulation play crucial roles in influencing and amplifying the spread of green behavior across society. To this end, a novel three-layer model in multilayer networks is proposed. In the novel model, the information layer describes green information spreading, the physical contact layer depicts green behavior propagation, and policy regulation is symbolized by an isolated node beneath the two layers. Then, we deduce the green behavior threshold for the three-layer model using the microscopic Markov chain approach. Moreover, subject to some individuals who are more likely to influence others or become green nodes and the limitations of the capacity of policy regulation, an optimal scheme is given that could optimize policy interventions to most effectively prompt green behavior.Subsequently, simulations are performed to validate the preciseness and theoretical results of the new model. It reveals that policy regulation can prompt the prevalence and outbreak of green behavior. Then, the green behavior is more likely to spread and be prevalent in the SF network than in the ER network. Additionally, optimal allocation is highly successful in facilitating the dissemination of green behavior. In practice, the optimal allocation strategy could prioritize interventions at critical nodes or regions, such as highly connected urban areas, where the impact of green behavior promotion would be most significant.展开更多
Ancient villages in Lingnan serve as crucial carriers of Lingnan culture.Their abundant cultural symbols now face the dual task of inheritance and innovation in the digital era.Drawing on Stuart Hall’s encoding/decod...Ancient villages in Lingnan serve as crucial carriers of Lingnan culture.Their abundant cultural symbols now face the dual task of inheritance and innovation in the digital era.Drawing on Stuart Hall’s encoding/decoding theory,this study explores how representative cultural symbols of Lingnan’s ancient villages are digitally translated and disseminated.By analyzing specific cases,it elucidates the logic of audience interaction and consumption during the decoding of these digital cultural symbols.This study aims to offer valuable insights for revitalizing ancient village culture and informing its sustainable industrial development.展开更多
Disseminated mucormycosis is a life-threatening fungal infection with high mortality,particularly in immunocompromised patients.Early diagnosis and prompt intervention are crutial but often delayed due to nonspecific ...Disseminated mucormycosis is a life-threatening fungal infection with high mortality,particularly in immunocompromised patients.Early diagnosis and prompt intervention are crutial but often delayed due to nonspecific presentations.Many studies have highlighted the challenges in emergency settings,where atypical symptoms may lead to misdiagnosis.We report a rare case of disseminated mucormycosis originating from the stomach in a pregnancy-induced thrombocytopenia(PITP)patient,emphasizing rapid gastroscopy examination,histopathological confi rmation,multidisciplinary management,and high-risk factors for hospital-acquired gastrointestinal mucormycosis infection.展开更多
Ideological and political education in higher education institutions is currently facing the practical challenge of discourse transformation.Traditional theoretical indoctrination models are unable to effectively alig...Ideological and political education in higher education institutions is currently facing the practical challenge of discourse transformation.Traditional theoretical indoctrination models are unable to effectively align with the cognitive characteristics and acceptance habits of young people.With the profound changes in the media ecosystem,the ideological and political discourse system urgently needs to transition from a one-way communication model to an interactive dialogue model.This paper focuses on the bidirectional construction logic of“concise extraction”and“concise dissemination,”revealing the innovative characteristics of the ideological and political discourse system in content creation,dissemination methods,and talent cultivation mechanisms under the new era.It provides new theoretical perspectives and practical reference frameworks for addressing the challenges of insufficient effectiveness in ideological and political education.展开更多
The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these...The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these structures.Scientific imagery combined with artistic expression can further expand the potential of imaging in educational dissemination and interdisciplinary applications.展开更多
The current international dissemination of China’s human rights discourse predominantly adopts a“sender-oriented”model,emphasizing the output of human rights discourse by transmitters while overlooking strategy adj...The current international dissemination of China’s human rights discourse predominantly adopts a“sender-oriented”model,emphasizing the output of human rights discourse by transmitters while overlooking strategy adjustments based on audience feedback.To some extent,the current approach has resulted in characteristics such as strong practical implementation but weak discourse,limited theoretical foundation,and insufficient recognition in China’s international human rights communication.Consequently,while China has achieved remarkable progress in its human rights endeavors,human rights issues remain a critical area of stigmatization by some Western countries.An“effect-oriented”mechanism for the international dissemination of China’s human rights discourse,therefore,aims to address this challenge by re-centering the audience as active participants in the communication process.By emphasizing the dual nature of human rights’international communication,this approach leverages the reflexive monitoring of initial transmitters throughout the dissemination process to finally construct a dynamic human rights discourse framework responsive to different time and space contexts.This mechanism directly confronts the diverse backgrounds of global audiences and the resulting varied interpretations of China’s human rights discourse.It advocates for dynamic evaluation of global dissemination outcomes based on audience feedback and the timely adaptation of communication strategies according to context.By doing so,it seeks to effectively advance China’s human rights communication efforts and enhance dissemination efficiency on the global scale.展开更多
Chinese Physics Letters(CPL) is a peer-reviewed, international and multidisciplinary journal sponsored by the Chinese Physical Society(CPS) and Institute of Physics, CAS,and hosted online by IOP Publishing Ltd. Launch...Chinese Physics Letters(CPL) is a peer-reviewed, international and multidisciplinary journal sponsored by the Chinese Physical Society(CPS) and Institute of Physics, CAS,and hosted online by IOP Publishing Ltd. Launched in 1984 as the flagship journal of CPS, CPL has become one of the most prestigious periodicals published in China, and been among the good choices for worldwide physicists to disseminate their most important breakthroughs.展开更多
文摘The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organizations and people does it refer to?How can be"earnest"?These questions are worth the contemplation of people like us who are performing China’s public diplomacy.
文摘Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant advantages of GAs,including improved clarity,increased reader engagement,and enhanced visibility of research findings.By transforming intricate scientific data into accessible visual formats,these abstracts facilitate quick and effective knowledge transfer,crucial in clinical decision-making and patient care.However,challenges such as potential data misrepresentation due to oversimplification,the skill gap in graphic design among researchers,and the lack of standardized creation guidelines pose barriers to their widespread adoption.Additionally,while software such as Adobe Illustrator,BioRender,and Canva are commonly employed to create these visuals,not all researchers may be proficient in their use.To address these issues,we recommend that academic journals establish clear guidelines and provide necessary design training to researchers.This proactive approach will ensure the creation of high-quality GAs,promote their standardization,and expand their use in clinical reporting,ultimately benefiting the medical community and improving healthcare outcomes.
文摘This paper is focused on discussing the case of Las Loras UNESCO Global Geopark,in Spain,as an example to show the contribution of Geoparks to the dissemination of science and the relevance of preserving geoheritage by implementing simple measures based on communication and prevention.Natural and anthropic hazards derived from climate change are endangering heritage and the well-ness of the society.Geoheritage is vulnerable.Nowadays we are witnessing the destruction of monuments with high emotional significance due to wars,but climate change is also contributing to the loss of the same cultural heritage.Prevention is often the best way to protect geoheritage from disappearing and society is the best agent to implement preventive measures.Citizens are often unaware of the important treasures they have around them.Geoparks have been a great tool to bring awareness in society,since by involving the public in the whole process of recognition and promotion,they protect the space and the cultural and economic values associated with them.It is important to communicate the initiatives taking place in the Geoparks to explain the importance of geology and the risk of losing the geoheritage if natural hazards increase.Las Loras study is a good practice to implement in other Geoparks.
文摘One of the most promising vector control strategies for controlling dengue fever is the stable introduction of the obligate intracellular Wolbachia bacteria strain into Aedes aegypti mosquitoes. This method reduces the mosquito’s ability to transmit dengue through reproductive strategies associated with Wolbachia infection, such as parthenogenesis, male elimination or feminization, sex ratio distortions and cytoplasmic incompatibility. Expert knowledge and a risk assessment framework were used to identify the risks associated with the release of Wolbachia-bearing mosquitoes. Then, consultations with individual participants were organized and a Bayesian network (BN) was developed to capture the relationship between the hazards as well as the likelihood of these adverse events occurring. Finally, risk was calculated from the probability and consequence estimates obtained from our Burkina Faso participants, using a questionnaire based on the identified risks. Our “Cause More Harm” study yielded 46.15% negligible risk, 44.23% very low risk and 9.62% low risk. The “socio-cultural change” parameter had the greatest influence, with the perception that the dissemination project would be poorly received by the local population. This parameter alone accounted for 80% of the most significant risks. This explains the fact that hazard RA 49 “negative messages in social media” is ranked as the highest individual risk (although the risk is low) with a calculated risk of 0.261. The risk assessment was designed to integrate the interdependent complexity of hazards likely to affect the dissemination of technology in the environment. It represents an important implementation phase in the success of this innovative research, introducing a new technology to combat the transmission of dengue fever.
文摘BACKGROUND Erythrodermic psoriasis(EP)is a rare and life-threatening form of psoriasis associated with significant morbidity and mortality.Systemic immunosuppre-ssive therapies are often required but may predispose to opportunistic infections.Disseminated herpes simplex virus type-1(HSV-1)is an unusual complication in otherwise immunocompetent patients and has not been reported in association with ixekizumab therapy for EP.CASE SUMMARY We describe a 49-year-old man with longstanding severe plaque psoriasis,liver cirrhosis,and bipolar disorder who developed EP involving>90%of body surface area[Psoriasis Area and Severity Index(PASI)45].Following initial stabil-ization,he was admitted to the intensive care unit(ICU)with hemodynamic instability,leukocytosis with eosinophilia,and diffuse desquamation.Ixekizumab was initiated with high-dose topical clobetasol.During his ICU stay,he developed recurrent bacteremias and neurologic decline(Glasgow Coma Scale 7/15),fo-llowed by the appearance of widespread vesicles and hemorrhagic crusts.HSV-1 infection was confirmed by polymerase chain reaction(PCR).Immunosuppressive therapy was withheld,and intravenous acyclovir was started,leading to progre-ssive improvement.After ten days,ixekizumab was reintroduced with careful monitoring,resulting in marked clinical improvement(PASI 9.7 at six weeks).The patient remained stable on long-term follow-up with oral acyclovir prophylaxis.CONCLUSION This case highlights the diagnostic and therapeutic challenges of managing EP in the setting of biologic therapy.Disseminated cutaneous HSV-1 should be considered in immunosuppressed patients presenting with new vesicular eruptions,and prompt PCR testing with early antiviral therapy is essential.A multidisciplinary approach is critical to balance immunosuppression for disease control with infection risk.
文摘In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans-lational Neuroscience.The author(s)shall grant the fol-lowing worldwide exclusive rights carried by the said article in different languages to Journal of Translational Neuroscience free of charge:reproductions,distribution,electronic dissemination,translation and compilation.The author(s)authorize(s)Journal of Translational Neu-roscience to register the said article(including all the in-termedia)with the proper copyright authorities.
文摘Transactions of Nanjing University of Acronautics&Astronautics(TNUAA)is a bimonthly joumnal facing intermational academic community.Emphasizing prompt and efective dissemination of key data and new scientific insights,TNUAA publishes experimental and theoretical papers bearing on applications to all branches of aeronautics,astronautics and civill aviation.
文摘BACKGROUND Histoplasmosis is a rare infectious condition with mainly pulmonary involvement which is generally self-limiting in immunocompetent individuals.Its manifestation varies and lacks specificity.This study reports a case of primary disseminated liver histoplasmosis in a normal host presenting as liver failure cured by liver transplantation and voriconazole.CASE SUMMARY A 43-year-old Chinese man with intermittent fever,malaise,jaundice and extreme hepatomegaly for more than 40 days was admitted to the Second Xiang-ya Hospital.The patient was immunocompetent and lacked a definitive history of exposure.His condition deteriorated to liver failure,and he promptly underwent liver transplantation to ensure survival.One year later,the patient presented with severe gastrointestinal symptoms,including fever,abdominal pain,and diarrhea.Subsequently,tissue samples acquired via gastrointestinal endoscopy were subjected to pathological examination and next-generation sequencing analysis.Through a comprehensive amalgamation of clinical presentation,biopsy pathology,and next-generation sequencing analysis,the patient was ultimately diagnosed with disseminated hepatic histoplasmosis.The patient achieved complete recovery after 6 months of voriconazole treatment.CONCLUSION In patients with chronic-hepatitis-B having atypical symptoms,histoplasmosis can be a differential diagnosis.Voriconazole is effective in treating histoplasmosis.
文摘Rationale:Melioidosis is a serious opportunistic infection caused by Burkholderia(B.)pseudomallei,primarily affecting immunocompromised individuals,particularly in endemic regions.Timely diagnosis and appropriate treatment are crucial to prevent fatal outcomes.Patient concerns:Case 1 was a 34-year-old male kidney transplant recipient who presented with a 15-day history of intermittent fever,accompanied by liver and spleen abscesses.Case 2 was a 37-year-old female kidney transplant recipient who presented with acute febrile illness and developed leucopenia.Blood cultures for both patients grew B.pseudomallei.Diagnosis:Both patients were diagnosed with melioidosis caused by B.pseudomallei,with the diagnosis confirmed through pus culture from the liver abscess in Case 1 and blood culture in Case 2.Interventions:Both patients were treated with an intensive regimen of meropenem(renal-adjusted doses),followed by a 3-month course of oral cotrimoxazole for eradication therapy.Outcomes:Case 1 experienced resolution of liver and spleen abscesses after 3 months of treatment and continued to recover well.In Case 2,blood cultures became sterile after 4 weeks,with no further complications observed.Lessons:Melioidosis should be suspected in immunocompromised patients,especially kidney transplant recipients,who present with unexplained fever and sepsis-like symptoms.Early diagnosis through aspiration of abscesses and prompt treatment are critical for preventing relapses and improving patient outcomes.
文摘In Burkina Faso, recent dengue outbreaks were exacerbated by Aedes aegypti mosquitoes, which have developed resistance to conventional insecticides. This study investigates the potential of Metarhizium pingshaense Met_S26, a fungus from Burkina Faso, for controlling both endophilic and exophilic Aedes mosquitoes. Traditional interventions are less effective against mosquitoes resting outdoors, and the ability of the fungus to be sexually transmitted could enhance its efficacy. Aedes mosquitoes were reared and exposed to various concentrations of Metarhizium pingshaense to assess its virulence. The fungus showed significant efficacy, with lethal times (LT80) ranging from 8.67 to 11.83 days depending on the concentration. Furthermore, bioassays demonstrated effective sexual auto-dissemination, with substantial transmission of fungal spores between infected and uninfected mosquitoes, leading to lower survival rates in uninfected mates. This study highlights Metarhizium pingshaense Met_S26 as a promising tool for controlling both indoor and outdoor Aedes populations, complementing existing vector control strategies such as the Sterile Insect Technique (SIT) and Wolbachia-based approaches. Future research should explore integrating this fungus with other control methods for a comprehensive vector management strategy.
文摘BACKGROUND Atopic dermatitis(AD),or eczema,is a chronic,pruritic inflammatory skin disease affecting children and adults.Socioeconomic status(SES)plays a significant role in developing AD.However,mixed evidence from a previous study by Bajwa et al makes it difficult to determine the directionality of the association.There is a lite-rature gap in understanding the causal association between AD and socioeco-nomic factors.AIM To evaluate the impact of disparities in SES on pediatric AD populations.METHODS Based on the eligibility criteria,the literature review identified eight articles since July 2021,and a descriptive analysis was conducted using an Excel spreadsheet on key components collected from the identified studies.RESULTS Eight observational studies assessed SES in pediatric AD.Five observational studies showed mixed associations between AD and SES.Sub-analysis revealed that urban areas had a higher prevalence of AD,and four studies identified a positive association between parental education and AD in the pediatric popu-lation.Socioeconomic variables,such as residential areas and household income,significantly influence disease outcomes.CONCLUSION There is mixed association between pediatric AD and SES,with AD positively associated with parental education.There is critical need to evaluate global impact of SES variables on pediatric AD.
文摘The application of short videos in agricultural scenarios has become a new form of productive force driving agricultural development,injecting new vitality and opportunities into traditional agriculture.These videos leverage the unique expressive logic of the platform by adopting a small entry point and prioritizing dissemination rate.They are strategically planned in terms of content,visuals,and interaction to cater to users needs for relaxation,knowledge acquisition,social sharing,agricultural product marketing,and talent display.Through careful design,full creativity,rich emotion,and the creation of distinct character personalities,these videos deliver positive,entertaining,informative,and opinion-driven agricultural content.The production and operation of agricultural short videos can be effectively optimized by analyzing the characteristics of both popular and less popular videos,and utilizing smart tools and trending topics.
基金Project supported by the National Natural Science Foundation of China (Grant No. 62371253)the Postgraduate Research and Practice Innovation Program of Jiangsu Province, China (Grant No. KYCX24_1179)。
文摘As the economy grows, environmental issues are becoming increasingly severe, making the promotion of green behavior more urgent. Information dissemination and policy regulation play crucial roles in influencing and amplifying the spread of green behavior across society. To this end, a novel three-layer model in multilayer networks is proposed. In the novel model, the information layer describes green information spreading, the physical contact layer depicts green behavior propagation, and policy regulation is symbolized by an isolated node beneath the two layers. Then, we deduce the green behavior threshold for the three-layer model using the microscopic Markov chain approach. Moreover, subject to some individuals who are more likely to influence others or become green nodes and the limitations of the capacity of policy regulation, an optimal scheme is given that could optimize policy interventions to most effectively prompt green behavior.Subsequently, simulations are performed to validate the preciseness and theoretical results of the new model. It reveals that policy regulation can prompt the prevalence and outbreak of green behavior. Then, the green behavior is more likely to spread and be prevalent in the SF network than in the ER network. Additionally, optimal allocation is highly successful in facilitating the dissemination of green behavior. In practice, the optimal allocation strategy could prioritize interventions at critical nodes or regions, such as highly connected urban areas, where the impact of green behavior promotion would be most significant.
基金2025 Institutional-Level Scientific Research Project of South China Business College,Guangdong University of Foreign Studies,“Digital Dissemination and Consumer Behaviour Research:Cultural Symbols of Lingnan Heritage Villages”(Project No.:25-005C)。
文摘Ancient villages in Lingnan serve as crucial carriers of Lingnan culture.Their abundant cultural symbols now face the dual task of inheritance and innovation in the digital era.Drawing on Stuart Hall’s encoding/decoding theory,this study explores how representative cultural symbols of Lingnan’s ancient villages are digitally translated and disseminated.By analyzing specific cases,it elucidates the logic of audience interaction and consumption during the decoding of these digital cultural symbols.This study aims to offer valuable insights for revitalizing ancient village culture and informing its sustainable industrial development.
基金supported by a grant from Guangdong Provincial Natural Science Foundation of China(2023A15115012665).
文摘Disseminated mucormycosis is a life-threatening fungal infection with high mortality,particularly in immunocompromised patients.Early diagnosis and prompt intervention are crutial but often delayed due to nonspecific presentations.Many studies have highlighted the challenges in emergency settings,where atypical symptoms may lead to misdiagnosis.We report a rare case of disseminated mucormycosis originating from the stomach in a pregnancy-induced thrombocytopenia(PITP)patient,emphasizing rapid gastroscopy examination,histopathological confi rmation,multidisciplinary management,and high-risk factors for hospital-acquired gastrointestinal mucormycosis infection.
文摘Ideological and political education in higher education institutions is currently facing the practical challenge of discourse transformation.Traditional theoretical indoctrination models are unable to effectively align with the cognitive characteristics and acceptance habits of young people.With the profound changes in the media ecosystem,the ideological and political discourse system urgently needs to transition from a one-way communication model to an interactive dialogue model.This paper focuses on the bidirectional construction logic of“concise extraction”and“concise dissemination,”revealing the innovative characteristics of the ideological and political discourse system in content creation,dissemination methods,and talent cultivation mechanisms under the new era.It provides new theoretical perspectives and practical reference frameworks for addressing the challenges of insufficient effectiveness in ideological and political education.
基金supported by the Fundamental Research Funds for the Central Universities(No.226-2024-00038),China.
文摘The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these structures.Scientific imagery combined with artistic expression can further expand the potential of imaging in educational dissemination and interdisciplinary applications.
基金This paper is a phased outcome of the“Research on the Strategy to Improve the Mechanism for the International Dissemination of China’s Human Rights Discourse”(22JJD820045),a key research project of the National Human Rights Education and Training Base under China’s Ministry of Education.
文摘The current international dissemination of China’s human rights discourse predominantly adopts a“sender-oriented”model,emphasizing the output of human rights discourse by transmitters while overlooking strategy adjustments based on audience feedback.To some extent,the current approach has resulted in characteristics such as strong practical implementation but weak discourse,limited theoretical foundation,and insufficient recognition in China’s international human rights communication.Consequently,while China has achieved remarkable progress in its human rights endeavors,human rights issues remain a critical area of stigmatization by some Western countries.An“effect-oriented”mechanism for the international dissemination of China’s human rights discourse,therefore,aims to address this challenge by re-centering the audience as active participants in the communication process.By emphasizing the dual nature of human rights’international communication,this approach leverages the reflexive monitoring of initial transmitters throughout the dissemination process to finally construct a dynamic human rights discourse framework responsive to different time and space contexts.This mechanism directly confronts the diverse backgrounds of global audiences and the resulting varied interpretations of China’s human rights discourse.It advocates for dynamic evaluation of global dissemination outcomes based on audience feedback and the timely adaptation of communication strategies according to context.By doing so,it seeks to effectively advance China’s human rights communication efforts and enhance dissemination efficiency on the global scale.
文摘Chinese Physics Letters(CPL) is a peer-reviewed, international and multidisciplinary journal sponsored by the Chinese Physical Society(CPS) and Institute of Physics, CAS,and hosted online by IOP Publishing Ltd. Launched in 1984 as the flagship journal of CPS, CPL has become one of the most prestigious periodicals published in China, and been among the good choices for worldwide physicists to disseminate their most important breakthroughs.
