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Research progress on subjective well-being and dispositional optimism of the elderly
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作者 Li Zhu Xiang-Shu Cui 《Psychosomatic Medicine Research》 2022年第3期24-29,共6页
The subjective well-being of the elderly is an integral part of healthy aging.This review introduces the concept of subjective well-being of the elderly and the evaluation tools used,reviews the influencing factors of... The subjective well-being of the elderly is an integral part of healthy aging.This review introduces the concept of subjective well-being of the elderly and the evaluation tools used,reviews the influencing factors of subjective well-being of the elderly,and summarizes the intervention measures of subjective well-being of the elderly.From the perspective of positive psychology,based on the introduction of the concept and evaluation tools of temperament optimism,this paper reviews the research status of temperament optimism and subjective well-being and the research progress of their correlation,so as to provide a theoretical basis for the intervention to improve the subjective well-being of the elderly. 展开更多
关键词 The elderly Subjective well-being dispositional optimism OVERVIEW
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Implicit and explicit emotion regulation in adolescents with dispositional optimism 被引量:2
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作者 Rong Zou Jiajin Yuan 《Brain Science Advances》 2021年第4期239-247,共9页
The development of adaptive emotion regulation(ER)plays a pivotal role in adolescent mental health and socio-emotional adaptation.Dispositional optimism,as an important protective factor for adolescent adjustment,may ... The development of adaptive emotion regulation(ER)plays a pivotal role in adolescent mental health and socio-emotional adaptation.Dispositional optimism,as an important protective factor for adolescent adjustment,may affect adolescent ER and subsequently influence adaptive outcomes.In this review,the changes and challenges,the role of ER in socio-emotional adjustment,and the developmental characteristics of implicit and explicit ER during adolescence are described.Subsequently,by employing the top-down model of personality,coping,and emotion,how dispositional optimism may affect psychological adjustment from the perspective of ER is analyzed.Furthermore,how the differences in adolescents’dispositional optimism may be reflected by the differences in implicit ER is discussed.Finally,recommendations for future research are outlined. 展开更多
关键词 emotion regulation dispositional optimism implicit emotion regulation positive expectancy ADOLESCENCE
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上海市食品安全风险监测评估和调查处置体系现状及对策 被引量:3
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作者 吴春峰 秦璐昕 +4 位作者 刘弘 蔡华 陆晔 郭常义 付晨 《中国卫生资源》 北大核心 2021年第1期71-74,共4页
分析上海市食品安全风险监测评估和调查处置体系调研数据,探讨上海市食品安全风险监测评估和调查处置体系建设现状、存在的主要问题,并提出对策与建议。当前现况和主要问题是:上海市食品安全风险监测评估和调查处置的体系架构已相对完整... 分析上海市食品安全风险监测评估和调查处置体系调研数据,探讨上海市食品安全风险监测评估和调查处置体系建设现状、存在的主要问题,并提出对策与建议。当前现况和主要问题是:上海市食品安全风险监测评估和调查处置的体系架构已相对完整,运转效率有待提升;工作的职责不断明确,人员队伍缺失严重;工作的规范有所提升,投入保障有待完善;实验平台技术领先,网络能级差距较大;信息化建设尚在起步阶段。建议加强政府引导,统筹规划,通过推进专业技术核心机构建设,加大人员队伍和设施设备的投入保障,完善食品安全的实验室网络构建,重点推进食品安全信息化建设,完善信息利用和共享机制等,进一步提升食品安全风险监测评估与调查处置在保障上海市居民食品安全中的作用。 展开更多
关键词 食品安全food safety 风险监测risk surveillance 调查处置investigation and disposition 对策分析countermeasure analysis 上海市Shanghai
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Analysis of Culture Expression in the Garden Plants Disposition 被引量:1
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作者 林汉 郄亚微 +2 位作者 徐有明 刘聪 赵巧只 《Journal of Landscape Research》 2009年第1期16-18,共3页
Culture of the garden plants disposition was expressed in many aspects,such as the plant disposition with special cultural environment and specific environment,expression of urban culture in the plant disposition,appl... Culture of the garden plants disposition was expressed in many aspects,such as the plant disposition with special cultural environment and specific environment,expression of urban culture in the plant disposition,application of plants with historical and cultural connotations in the design and protection for ancient and famous trees. 展开更多
关键词 GARDEN plant DISPOSITION CULTURE LANDSCAPE EXPRESSION
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Study on Plants Selection and Disposition in High-grade Residences 被引量:1
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作者 张若冰 包志毅 《Journal of Landscape Research》 2011年第5期49-51,共3页
With rapid development of economy and emergence of more and more high-grade residences,it had highlighted that high-grade residence was the inevitable tendency of economic development and urban construction.Based on t... With rapid development of economy and emergence of more and more high-grade residences,it had highlighted that high-grade residence was the inevitable tendency of economic development and urban construction.Based on the fact that high-grade residences paid more attention to harmony of human and architecture with nature and required higher for landscaping,the paper emphasized that landscape quality of high-grade residences was the key factor deciding quality of the residence.In view of insufficiencies of plant landscaping planning in high-grade residences at home and abroad,by taking high-grade residences in Hangzhou City for example,analysis had been conducted by selecting typical cases.It pointed out that plants disposition in high-grade residences was unreasonable,architectures and landscapes were isolated,and greening ratio was stressed while design was neglected.And then,corresponding solutions had been proposed.In terms of plants selection,it should reasonably utilize native tree species,and properly select new and high-quality plant species.In terms of harmonious unity between plant landscape and architecture,it should lay stress on unity between sensory design and comfort design.In terms of plant design and disposition,it should stick to the theme of "residential environment",so as to rationalize plant design and disposition,and create more comfortable residential environment. 展开更多
关键词 HIGH-GRADE RESIDENCES PLANTS LANDSCAPE Plant DISPOSITION RESIDENTIAL environment
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试论disposition概念的伦理意蕴 被引量:1
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作者 陈晓曦 《郑州轻工业学院学报(社会科学版)》 2016年第2期30-36,共7页
disposition是道德哲学中的一个重要范畴,其基本涵义是道德意向或道德性情。古往今来,许多道德哲学家都对此做过深入分析。亚里士多德的《尼各马可伦理学》明确地将disposition视为"理性规训",并且从伦理德性和理智德性两个... disposition是道德哲学中的一个重要范畴,其基本涵义是道德意向或道德性情。古往今来,许多道德哲学家都对此做过深入分析。亚里士多德的《尼各马可伦理学》明确地将disposition视为"理性规训",并且从伦理德性和理智德性两个层面强调了这一范畴的形而上意蕴。康德的《实践理性批判》从人性分析和人如何向善的角度,赋予disposition这一范畴以更加具体的内容。康德坚持人性善恶并存的观点,把disposition界定为向善的禀赋,并且赋予其三重内涵,即机械性质的自保自爱、人超越于物的类本质意识和敬重道德普遍法则的敏感性人格。另外,哈奇森也对disposition做出了自己的界定。哈奇森力图在情感领域确立一个秩序,以阐明道德意识结构,disposition成了他判断道德与否的一个易感性的尺度和关键位置,它指向何处,将直接决定人的道德善恶倾向。回顾以上这些哲学家们关于disposition的思想和观点,发现在disposition这个重要的道德哲学范畴里蕴含着伦理学的原初家园追求。精神世界、道德世界的理想无疑也是建立一种家园,让出于种种原因暂时不能在家园安顿的人,回归到其应有的居所。这个理想的实现过程,恰恰也是性情的调整、意向态度的觉悟、情感秩序的确立及灵魂的再安顿过程。 展开更多
关键词 DISPOSITION 易感性 性情理论 伦理态度 道德情感
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Depressive symptoms and their associated factors in heart failure patients 被引量:1
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作者 Deng-Xin He Ming-Hao Pan 《Frontiers of Nursing》 2021年第4期389-397,共9页
Objectives:Depressive symptoms are common in heart failure(HF)patients and they may exacerbate the progression of HF.Thus,identifying associations with depressive symptoms is essential to develop effective interventio... Objectives:Depressive symptoms are common in heart failure(HF)patients and they may exacerbate the progression of HF.Thus,identifying associations with depressive symptoms is essential to develop effective interventions to alleviate patients’depressive symptoms.Therefore,this study aimed to explore the factors related to HF patients’depressive symptoms.Methods:Potential hospitalized patients were recruited from a university-affiliated hospital by convenience sampling.This study included 321 HF patients who had completed information about depressive symptoms,functional capacity,social support,dispositional optimism,self-care confidence,and health literacy.Descriptive statistics were used to characterize the sample.Independent group t-tests and one-way analysis of variance were used to assess the difference in depressive symptoms score in demographic and clinical characteristics,while Pearson’s correlation was used to assess the associations among continuous variables.Results:The scores for functional capacity,social support,dispositional optimism,self-care confidence,and health literacy were negatively associated with the score for depressive symptoms.The interaction effect between the functional capacity and the dispositional optimism on depressive symptoms was significant.Conclusions:Interventions targeted improving the above-mentioned factors may be beneficial to reduce depressive symptoms in HF patients. 展开更多
关键词 depressive symptoms dispositional optimism functional capacity heart failure social support
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Analysis of the Current Situation and Disposition of Roadside Trees in Yangling City of China
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作者 张淑英 代亚丽 《Journal of Landscape Research》 2011年第10期54-58,61,共6页
Based on relevant materials, the paper had analyzed the macro-function of roadside trees from the perspectives of urban eco-environment construction and urban plants landscape construction. By taking Yangling City as ... Based on relevant materials, the paper had analyzed the macro-function of roadside trees from the perspectives of urban eco-environment construction and urban plants landscape construction. By taking Yangling City as the demonstration area, the field study had been conducted on trees along 38 roads, which had been analyzed from the aspects of the species of roadside trees, disposition modes and seasonable change. It had found that roadside trees were abundant, including 27 species belonging to 22 families, but the disposition mode was simple. In view of existing problems, suggestions had been proposed. It should make use of native tree species to construct regional characteristic roads; enhance evergreen tree species and enrich seasonable scenery; cultivate fast-growing and slowly-growing tree species alternately and avoid landscape blank; dispose upper, middle and lower layer of plants species reasonably and construct multiple layers of plants landscape. Several good roadside tree species had been recommended, so as to provide scientific reference for roadside greening construction. 展开更多
关键词 ROADSIDE trees SURVEY TREE SPECIES DISPOSITION
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Study on Garden Plant Species and Their Disposition Optimization in Arid Valley of West China
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作者 谢学强 《Journal of Landscape Research》 2010年第12期68-72,共5页
Based on survey of plant species and disposition in major gardens at arid valley and optimization of plant disposition in Sichuan University for Nationalities,the study pointed out the overall target for disposition o... Based on survey of plant species and disposition in major gardens at arid valley and optimization of plant disposition in Sichuan University for Nationalities,the study pointed out the overall target for disposition optimization of garden plants in arid valley,concluded the principles and approaches to optimize garden plant disposition at arid valley and highlight garden features at arid valley,emphasized the vital significance to develop local wild plant resources and introduce exotic garden plants. 展开更多
关键词 ARID valley GARDEN PLANT species PLANT DISPOSITION OPTIMIZATION
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Study on Application of Landscape Plants in Residential Area—A Case Study of "Senqiao Yinxiang" Residential Area in Chizhou City
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作者 汪诗德 《Journal of Landscape Research》 2010年第12期63-67,共5页
With ecological theory followed during disposition and application of landscape plants in residential area as the guidance,ecological landscape concept was established.It emphasized that landscape plants disposition s... With ecological theory followed during disposition and application of landscape plants in residential area as the guidance,ecological landscape concept was established.It emphasized that landscape plants disposition should aim at making the nature reappear,ameliorating and maintaining ecological balance in residential area,with harmonious coexistence between human and nature as the goal,and with systematicness of landscape greening,diversity of biological development and sustainability of plant landscaping as the mission,so as to achieve plane systematicness,spatial hierarchy and temporal relevance. 展开更多
关键词 RESIDENTIAL area Landscape plants DISPOSITION and APPLICATION ECOLOGICAL VIEW AESTHETIC VIEW
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和谐人格的塑造与德育价值观更新
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作者 刘根平 《教育论丛》 1987年第1期50-54,65,共6页
一、和谐人格的理想结构与德育的缺陷人格,英文中通常有三种含义:(1)personality(个人的存在);(2)character(性格);(3)moral quailty(道德品质)。而英文中“性格”一词又有三种基本含义:(1)nature(肉体、精神的自然与本性);(2)dispositi... 一、和谐人格的理想结构与德育的缺陷人格,英文中通常有三种含义:(1)personality(个人的存在);(2)character(性格);(3)moral quailty(道德品质)。而英文中“性格”一词又有三种基本含义:(1)nature(肉体、精神的自然与本性);(2)disposition(倾向性);(3)tem perament(气质).从辞源中,我们发现,人格首先体现为其层级性。 展开更多
关键词 PERSONALITY 道德品质 和谐发展 DISPOSITION 层级性 人格形成 审美基础 思想政治教育 效果评价标准 社会化的过程
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Critical Thinking Disposition among Nurses Working in Puplic Hospitals at Port-Said Governorate 被引量:4
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作者 Amal Sobhy Mahmoud Hind Abdullah Mohamed 《International Journal of Nursing Sciences》 2017年第2期128-134,共7页
Aim: This study aimed to investigate critical thinking disposition among nurses working in Public Hospitals in Port-Said Governorate.Methods: A descriptive research design was conducted in this study. Totally 196 resp... Aim: This study aimed to investigate critical thinking disposition among nurses working in Public Hospitals in Port-Said Governorate.Methods: A descriptive research design was conducted in this study. Totally 196 respondents were chosen by systemic random sampling, to take part in the study as the sample. Data was collected from April to September in 2015. Tools of data collection: A personal and job characteristics data sheet and California Critical Thinking Disposition Inventory(CCTDI) were used. Results: The results revealed that the total critical thinking disposition score mean was 257.05 ± 20.16 and the highest score mean was 48.67 ± 6.28 for inquisitiveness subscale, while the lowest score mean was 21.36 ± 7.19 for the truth-seeking subscale. Also, none of the personal&job characteristics showed statistically significant relations with the total critical thinking disposition. Conclusion: More than three quarters of the nurses had an ambivalent disposition toward critical thinking, and most nurses' scores indicated a negative tendency towards truth-seeking. So the findings pointed for upgrading nurses' critical thinking through educational programs and a need for more problem-based learning with advanced teaching strategies in clinical areas. 展开更多
关键词 California critical thinking disposition Critical thinking disposition Nurses
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Three-axis magnetic flux leakage in-line inspection simulation based on finite-element analysis 被引量:4
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作者 冯健 张峻峰 +2 位作者 卢森骧 王宏阳 马瑞泽 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第1期531-536,共6页
With the increase of pipelines, corrosion leakage accidents happen frequently. Therefore, nondestructive testing technology is important for ensuring the safe operation of the pipelines and energy mining. In this pape... With the increase of pipelines, corrosion leakage accidents happen frequently. Therefore, nondestructive testing technology is important for ensuring the safe operation of the pipelines and energy mining. In this paper, the structure and principle of magnetic flux leakage (MFL) in-line inspection system is introduced first. Besides, a mathematic model of the system according to the ampere circuit rule, flux continuity theorem, and column coordinate transform is built, and the magnetic flux density in every point of space is calculated based on the theory of finite element analysis. Then we analyze and design the disposition of measurement section probes and sensors combining both three-axis MFL in-line inspection and multi-sensor fusion technology. Its advantage is that the three-axis changes of magnetic flux leakage field are measured by the multi-probes at the same time, so we can determine various defects accurately. Finally, the theory of finite element analysis is used to build a finite element simulation model, and the relationship between defects and MFL inspection signals is studied. Simulation and experiment results verify that the method not only enhances the detection ability to different types of defects but also improves the precision and reliability of the inspection system. 展开更多
关键词 magnetic flux leakage in-line inspection multi-sensor data fusion sensor disposition finite element analysis
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New application notion of pipeline transport——integrated in industry solid waste innocuous and efficient disposition 被引量:5
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作者 陈洁 赵学义 +4 位作者 王星 潘越 张娜 吴钰晶 吴淼 《Journal of Coal Science & Engineering(China)》 2006年第2期75-79,共5页
In order to solve transport problems of industry solid,firstly,a new applicationnotion of pipeline transport was presented,that is to say,combining pretreatment andtransport with disposal techniques of industry solid ... In order to solve transport problems of industry solid,firstly,a new applicationnotion of pipeline transport was presented,that is to say,combining pretreatment andtransport with disposal techniques of industry solid waste.Secondly,the integrated dis-posal and transport system for industry solid waste was introduced,in particular,the oper-ating principles,equipment set-up,key technology and technical parameters.Next,thispaper illustrated the application of this integrated system.Such as it can transport coalsludge with sufficiently high solids content(about 72%~77%)and high apparent viscosity(about 1 000~3 000 Pa.s)directly by pipeline having no use for water and addition agent.Generally,the transport distance is about 1 000 m.This system has been successfullyused in innocuous disposition and efficient utilization of other industrial byproducts or solidwastes,such as city sludge and paper making waste.The integrated system causes nopollution to the environment for its complete seal and realizes protecting the environment,conserving the energy,promoting the development of cycling economic.Finally,the paperdiscussed the research works that were needed for studying such pipeline transport sys-tem and narrates the relevant condition and application status. 展开更多
关键词 pipeline transport industry solid waste circulating fluidized bed boiler in- nocuous disposition rheologic behaviors pipeline transport properties
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Organo-Petrographic and Pore Facets of Permian Shale Beds of Jharia Basin with Implications to Shale Gas Reservoir 被引量:2
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作者 Vinod Atmaram Mendhe Subhashree Mishra +6 位作者 Ranjit G.Khangar Alka Damodhar Kamble Durgesh Kumar Atul Kumar Varma H.Singh Sujeet Kumar Mollika Bannerjee 《Journal of Earth Science》 SCIE CAS CSCD 2017年第5期897-916,共20页
The shale deposits of Damodar Valley have received great attention since preliminary studies indicate their potential for shale gas. However, fundamental information allied to shale gas re- servoir characteristics are... The shale deposits of Damodar Valley have received great attention since preliminary studies indicate their potential for shale gas. However, fundamental information allied to shale gas re- servoir characteristics are still rare in India, as exploration is in the primary stage. In this study, Ba- rakar shale beds of eastern part of Jharia Basin are evaluated for gas reservoir characteristics. It is evident that Barakar shales are carbonaceous, silty, contains sub-angular flecks of quartz and mica, irregular hair-line fractures and showing lithological variations along the bedding planes, signifying terrestrial-fluviatile deposits under reducing environment. The values of TOC varies from 1.21 wt.% to 17.32 wt.%, indicating good source rock potentiality. The vitrinite, liptinite, inertinite and mineral matter ranging from 0.28 vol.% to 12.98 vol.%, 0.17 vol.% to 3.23 vol.%, 0.23 vol.% to 9.05 vol.%, and 74.74 vol.% to 99.10 vol.%, respectively. The ternary facies plot of maceral composition substan- tiated that Barakar shales are vitrinite rich and placed in the thermal-dry gas prone region. The low values of the surface area determined following different methods point towards low methane storage capacity, this is because of diagenesis and alterations of potash feldspar responsible for pore blocking effect. The pore size distribution signifying the micro to mesoporous nature, while Type II sorption curve with the H2 type of hysteresis pattern, specifies the heterogeneity in pore structure mainly combined-slit and bottle neck pores. 展开更多
关键词 shale gas petrographic composition surface area pore disposition pore volume.
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Status Quo and Development Prospects of Vertical Greening in Urban Districts of Chongqing City 被引量:2
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作者 MA Lihui XIE Yingzan +2 位作者 FANG Wen HUANG Shiyou LIU Yanxin 《Journal of Landscape Research》 2013年第5期11-13,16,共4页
On the basis of investigating vertical greening in urban districts of Chongqing City, major problems were analyzed, dominant greening patterns were summarized, and major plant species suitable for the vertical greenin... On the basis of investigating vertical greening in urban districts of Chongqing City, major problems were analyzed, dominant greening patterns were summarized, and major plant species suitable for the vertical greening of urban districts in Chongqing City were given. On this basis, key technologies and development prospects of the vertical greening were explored. 展开更多
关键词 CHONGQING VERTICAL GREENING PLANTING DISPOSITION ECO-CITY
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Realizing profits immediately:disposition effect of open-end fund investors in China 被引量:1
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作者 Li Yajing1 Zhu Hongquan2 Luan Mingjing2(1 School of Economics and Management, University of Electronic Science and Technology of China,Chengdu 610054, China)(2 School of Economics and Management, Southwest Jiaotong University, Chengdu 610031, China) 《Journal of Southeast University(English Edition)》 EI CAS 2008年第S1期180-186,共7页
This paper explores the disposition effect, the tendency of investors to hold losing investments too long and sell winning investments too soon, by analyzing a unique data set that consists of the buying and selling p... This paper explores the disposition effect, the tendency of investors to hold losing investments too long and sell winning investments too soon, by analyzing a unique data set that consists of the buying and selling positions of open-end fund investors in China. Results show that investors' buying and selling behaviors are significantly affected by fund performance. The reasons that lie behind such results are mainly related to the non-persistence of fund performance. When fund performance is non-persistent, investors are not clear about the future returns on funds. So, investors, especially individual investors, would have to realize the profits on hand immediately. Meanwhile, fund investors are highly sensitive to fund age and loading fees, but not sensitive to management fees charged by funds when they buy or sell fund shares. 展开更多
关键词 INVESTORS open-end fund disposition effect fund shares
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ANALYSIS OF HYDRAULIC POWER SOURCES DISPOSITION AND ENERGY CONSUMPTION FOR HYDRAULIC DRILL RIG 被引量:1
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作者 He, Qinghua 《中国有色金属学会会刊:英文版》 EI CSCD 1995年第2期120-126,共7页
ANALYSISOFHYDRAULICPOWERSOURCESDISPOSITIONANDENERGYCONSUMPTIONFORHYDRAULICDRILLRIG¥He,Qinghua(DepartmentofMa... ANALYSISOFHYDRAULICPOWERSOURCESDISPOSITIONANDENERGYCONSUMPTIONFORHYDRAULICDRILLRIG¥He,Qinghua(DepartmentofMachineEngineering,... 展开更多
关键词 HYDRAULIC DRILL rig HYDRAULIC POWER source DISPOSITION ENERGY CONSUMPTION
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Application of CITYgreen5.0 model to tender appraisement of small-scale green-space designs 被引量:1
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作者 LIAO Wen-yan ZHAO Lin-sen 《Forestry Studies in China》 CAS 2008年第2期112-118,共7页
Developed by the American Forests, CITYgreen5.0 model has been widely applied to urban forestry research and has played an important role in analyzing quantitatively the ecological benefits produced by varied green-sp... Developed by the American Forests, CITYgreen5.0 model has been widely applied to urban forestry research and has played an important role in analyzing quantitatively the ecological benefits produced by varied green-space ecosystems. One of the functions of this model is to evaluate quickly and objectively on parts of the ecological benefits possibly produced by different design schemes for the same small-scale green-space project before the establishment. A comparative analysis was conducted by modeling partial ecological benefits potentially produced by green-spaces of two different design schemes for the same roof garden of Chuangfushidai-Junjingyuan in Shenzhen, given the growth status of plants both immediately after the establishment and 20 years later. Meanwhile, the project costs for each design scheme were also taken into consideration. The results showed that scheme II, mainly designed with a natural style of plant disposition, had a better greenery structure than that of scheme I, which was basically designed with a regular style of plant disposition. The estimated value of the partial ecological benefits produced by scheme II was larger than that of scheme I and the benefit-cost ratio of scheme II was more rational. It was suggested that scheme II be put into practice. 展开更多
关键词 CITY green 5.0 GARDEN design ecological benefit evaluation plant disposition
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Classification of natural products as sources of drugs according to the biopharmaceutics drug disposition classification system(BDDCS) 被引量:1
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作者 LI Ji Caroline A.Larregieu Leslie Z.Benet 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2016年第12期888-897,共10页
Natural products(NPs) are compounds that are derived from natural sources such as plants, animals, and microisms. Therapeutics has benefited from numerous drug classes derived from natural product sources. The Biophar... Natural products(NPs) are compounds that are derived from natural sources such as plants, animals, and microisms. Therapeutics has benefited from numerous drug classes derived from natural product sources. The Biopharmaceutics Drug position Classification System(BDDCS) was proposed to serve as a basis for predicting the importance of transporters and enzymes in determining drug bioavailability and disposition. It categorizes drugs into one of four biopharmaceutical classes according to their water solubility and extent of metabolism. The present paper reviews 109 drugs from natural product sources: 29% belong to class 1(high solubility, extensive metabolism), 22% to class 2(low solubility, extensive metabolism), 40% to class 3(high solubility, poor metabolism), and 9% to class 4(low solubility, poor metabolism). Herein we evaluated the characteristics of NPs in terms of BDDCS class for all 109 drugs as wells as for subsets of NPs drugs derived from plant sources as antibiotics. In the 109 NPs drugs, we piled 32 drugs from plants, 50%(16) of total in class 1, 22%(7) in class 2 and 28%(9) in class 3, none found in class 4; Meantime, the antibiotics were found 5(16%) in class 2, 22(71%) in class 3, and 4(13%) in class 4; no drug was found in class 1. Based on this classification, we anticipate BDDCS to serve as a useful adjunct in evaluating the potential characteristics of new natural products. 展开更多
关键词 Biopharmaceutics Drug Disposition Classification System(BDDCS) Natural products(NPs) Dose number Solubility and extent of metabolism
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