The potential migration of chemicals from disposable biodegradable tableware into food raises safety concerns regarding human health.This study utilized an ultra-high-performance liquid chromatography/quadrupole timeo...The potential migration of chemicals from disposable biodegradable tableware into food raises safety concerns regarding human health.This study utilized an ultra-high-performance liquid chromatography/quadrupole timeofflight mass spectrometry(UPLC-QTOF/MS)for the non-targeted identification of chemical migrants in 41 commercially available disposable biodegradable tableware products in the Chinese market.A total of 303 migrant compounds were identified,comprising primarily 123 oligomers,45 esters,and 31 amines.In addition,the predominant additives and related substances included 58 slip agents,27 antistatic agents,and 22 antioxidants.To comprehensively evaluate potential hazards for chemical migrants,we enhanced an existing toxicity risk matrix by incorporating endocrine disruption-related toxicity endpoints.The developed risk classification strategy was employed to categorize the 303 migrants into distinct risk levels.Notably,47 substances were classified as posing the highest risk level(RISK I),which primarily comprised slip agents(e.g.palmitamide),antioxidant degradation products(e.g.bis(2,4-di-tert-butylphenyl)phosphonate,7,9-di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione),and plasticizers(e.g.triisobutyl phosphate),In conclusion,this study presents a comprehensive methodology and offers a scientific basis for the safety assessment of chemical migrants in disposable biodegradable tableware.展开更多
基金the National Natural Science Foundation of China(32472450)。
文摘The potential migration of chemicals from disposable biodegradable tableware into food raises safety concerns regarding human health.This study utilized an ultra-high-performance liquid chromatography/quadrupole timeofflight mass spectrometry(UPLC-QTOF/MS)for the non-targeted identification of chemical migrants in 41 commercially available disposable biodegradable tableware products in the Chinese market.A total of 303 migrant compounds were identified,comprising primarily 123 oligomers,45 esters,and 31 amines.In addition,the predominant additives and related substances included 58 slip agents,27 antistatic agents,and 22 antioxidants.To comprehensively evaluate potential hazards for chemical migrants,we enhanced an existing toxicity risk matrix by incorporating endocrine disruption-related toxicity endpoints.The developed risk classification strategy was employed to categorize the 303 migrants into distinct risk levels.Notably,47 substances were classified as posing the highest risk level(RISK I),which primarily comprised slip agents(e.g.palmitamide),antioxidant degradation products(e.g.bis(2,4-di-tert-butylphenyl)phosphonate,7,9-di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione),and plasticizers(e.g.triisobutyl phosphate),In conclusion,this study presents a comprehensive methodology and offers a scientific basis for the safety assessment of chemical migrants in disposable biodegradable tableware.
