期刊文献+
共找到12,697篇文章
< 1 2 250 >
每页显示 20 50 100
Perspectives on Transcranial Direct Current Stimulation(tDCS)and Its Potential Integration With Nuclear Medicine as a Therapeutic Approach
1
作者 Suman Pradhan Subhasish Chatterjee Mousumi Saha 《Asia Pacific Journal of Clinical Medical Research》 2026年第1期1-4,共4页
Transcranial direct current stimulation(tDCS)is a non-invasive technique that modifies cortical excitability and induces neuroplasticity using low-intensity electrical currents.Nuclear medicine technologies like posit... Transcranial direct current stimulation(tDCS)is a non-invasive technique that modifies cortical excitability and induces neuroplasticity using low-intensity electrical currents.Nuclear medicine technologies like positron emission tomography(PET)and single-photon emission computed tomography(SPECT)can quantify cerebral metabolism and other dynamics.Evidence suggests that combining tDCS with these imaging methods enhances understanding and outcomes for neurological and psychiatric conditions.This review highlights how nuclear medicine can objectively characterize tDCS eff ects,map network modulation,and identify predictive biomarkers.PET and SPECT indicate changes in glucose metabolism and neurotransmitter activity post-tDCS,demonstrating their value in validation.While the co-application of these methodologies is still in conceptual stages,their integration may advance precision neuromodulation and inform rehabilitation strategies. 展开更多
关键词 DEPRESSION Nuclear Medicine Transcranial direct current Stimulation Cortical Excitability Neuronal Plasticity TOMOGRAPHY
暂未订购
A Composite Multi-Port Hybrid DC Circuit Breaker with DC Power Flow and Fault Current Limitation Abilities
2
作者 Xiaoya Chen Chao Zhang +5 位作者 Xufeng Yuan Wei Xiong Zhiyang Lu Huajun Zheng Yutao Xu Zhukui Tan 《Energy Engineering》 2026年第3期306-325,共20页
To address the issues of high costs and low component utilization caused by the independent configuration of hybrid DC circuit breakers(HCBs)and DC power flow controllers(DCPFCs)at each port in existing DC distributio... To address the issues of high costs and low component utilization caused by the independent configuration of hybrid DC circuit breakers(HCBs)and DC power flow controllers(DCPFCs)at each port in existing DC distribution networks,this paper adopts a component sharing mechanism to propose a composite multi-port hybrid DC circuit breaker(CM-HCB)with DC power flow and fault current limitation abilities,as well as reduced component costs.The proposed CM-HCB topology enables the sharing of the main breaker branch(MB)and the energy dissipation branch,while the load commutation switches(LCSs)in the main branch are reused as power flow control components,enabling flexible regulation of power flow in multiple lines.Meanwhile,by reconstructing the current path during the fault process,the proposed CM-HCB can utilize the internal coupled inductor to limit the current rise rate at the initial stage of the fault,significantly reducing the requirement for breaking current.A detailed study on the topological structure,steady-state power flow regulation mechanism,transient fault isolation mechanism,control strategy and characteristic analysis of the proposed CM-HCB is presented.Then,a Matlab/Simulink-based meshed three-terminal DC grid simulation platform with the proposed CM-HCB is built.The results indicate that the proposed CM-HCB can not only achieve flexible power flow control during steady-state operation,but also obtain current rise limitation and fault isolation abilities under short-circuit fault conditions,verifying its correctness and effectiveness.Finally,a comparative economic analysis is conducted between the proposed CM-HCB and the other two existing solutions,confirming that its component sharing mechanism can significantly reduce the number of components,lower system costs,and improve component utilization. 展开更多
关键词 dc power grid dc power flow control fault current limiting fault isolation hybrid dc circuit breaker
在线阅读 下载PDF
Does transcranial direct current stimulation enhance the hypoalgesic effect of exercise?
3
作者 Aidan Lewis Ben Rattray +1 位作者 Constantino Toufexis Andrew Flood 《Sports Medicine and Health Science》 2026年第1期102-109,共8页
Exercise produces a decrease in pain sensitivity via an effect called exercise-induced hypoalgesia(EIH).Transcranial direct current stimulation(tDCS),acting on similar analgesic mechanisms as EIH,represents a potentia... Exercise produces a decrease in pain sensitivity via an effect called exercise-induced hypoalgesia(EIH).Transcranial direct current stimulation(tDCS),acting on similar analgesic mechanisms as EIH,represents a potential complementary intervention that may amplify the effects of exercise on pain.This study aimed to explore if anodal tDCS could enhance the effect of exercise on pain compared to exercise alone.A total of 35 healthy participants aged 19–37 years completed a familiarisation session followed by two separate sessions where active and sham tDCS was applied in a randomised cross-over design.The familiarisation session involved familiarisation to the pain assessment and exercise tasks,while the subsequent tDCS sessions involved pain sensitivity assessment,exercise and either anodal tDCS or sham tDCS.tDCS doses were applied at 2 mA over the primary motor cortex for 10 min,with the reference electrode placed over the contralateral supraorbital area.The exercise task involved a sustained isometric grip strength contraction at 35%of maximal voluntary contraction(MVC)until volitional exhaustion.Pain sensitivity was evaluated as pressure pain threshold before tDCS,after tDCS,and after exercise.Across both tDCS conditions,pain threshold was higher after exercise when compared to pre-and post-tDCS measurement.This increase in pain threshold did not differ between active and sham tDCS conditions.Our findings suggest that the hypoalgesic effects of active anodal tDCS over the motor cortex prior to exercise are no greater than the effects of sham tDCS prior to exercise. 展开更多
关键词 Transcranial direct current stimulation Grip strength Pain sensitivity Time to exhaustion Pain pressure threshold TdcS
在线阅读 下载PDF
Effects of transcranial direct current stimulation (tDCS) for auditory hallucinations: A systematic review 被引量:1
4
作者 Haibin LI Yiran WANG +2 位作者 Jiangling JIANG Wei LI Chunbo LI 《上海精神医学》 CSCD 2016年第6期301-308,共8页
关键词 TdcS 电刺激 系统 直流 随机对照试验 中文科技期刊数据库 医学文献数据库 精神分裂症
在线阅读 下载PDF
Integrated Equipment with Functions of Current Flow Control and Fault Isolation for Multiterminal DC Grids 被引量:1
5
作者 Shuo Zhang Guibin Zou 《Energy Engineering》 EI 2025年第1期85-99,共15页
The multi-terminal direct current(DC)grid has extinctive superiorities over the traditional alternating current system in integrating large-scale renewable energy.Both the DC circuit breaker(DCCB)and the current flow ... The multi-terminal direct current(DC)grid has extinctive superiorities over the traditional alternating current system in integrating large-scale renewable energy.Both the DC circuit breaker(DCCB)and the current flow controller(CFC)are demanded to ensure the multiterminal DC grid to operates reliably and flexibly.However,since the CFC and the DCCB are all based on fully controlled semiconductor switches(e.g.,insulated gate bipolar transistor,integrated gate commutated thyristor,etc.),their separation configuration in the multiterminal DC grid will lead to unaffordable implementation costs and conduction power losses.To solve these problems,integrated equipment with both current flow control and fault isolation abilities is proposed,which shares the expensive and duplicated components of CFCs and DCCBs among adjacent lines.In addition,the complicated coordination control of CFCs and DCCBs can be avoided by adopting the integrated equipment in themultiterminal DC grid.In order to examine the current flow control and fault isolation abilities of the integrated equipment,the simulation model of a specific meshed four-terminal DC grid is constructed in the PSCAD/EMTDC software.Finally,the comparison between the integrated equipment and the separate solution is presented a specific result or conclusion needs to be added to the abstract. 展开更多
关键词 Integrated equipment multiterminal direct current grid current flow control fault isolation
在线阅读 下载PDF
Clay Minerals Channels Identification in the Tindikala-Boutou Area (Eastern-Cameroon) along the Kadey River Using Direct Current (DC) Method
6
作者 Daniel Hervé Gouet Arsène Meying +1 位作者 Stéphane Patrick Assembe Théophile Ndougsa-Mbarga 《Journal of Geoscience and Environment Protection》 2015年第6期123-133,共11页
To achieve the current study, geoelectrical surveys along six (06) profiles of 4 km long in a 100 m × 200 m grid defined according to the triangulation principle in the Tindikala-Boutou (Eastern-Cameroon) area al... To achieve the current study, geoelectrical surveys along six (06) profiles of 4 km long in a 100 m × 200 m grid defined according to the triangulation principle in the Tindikala-Boutou (Eastern-Cameroon) area along the Kadey River have been made through electrical sounding and profiling following Schlumberger array. The instrument is the resistive meter Syscal Junior 48 (IRIS Instrument). The data have been processed and modelled with Res2Dinv and Winsev softwares, and then interpolated with Surfer software. Investigation method used is the Direct Current (DC) method. Interpretations and analyses of results from the investigation method highlight weak zones or conductive discontinuities. The latter has been identified as shear zones within granitic structures of the Precambrian basement, according to the geologic and tectonic background of the area. The structural trend of these shear zones is E-W approximately. The mineralization characterized by conductive zones proves the presence of clay minerals disseminated in weathered quartz vein, which cross the shear zones. The intense activities of gold washers encountered in the studied area are able to attest the presence of clay minerals concentrations. 展开更多
关键词 Geoelectrical Surveys direct current METHOD RESISTIVITY Shear ZONES Clay MINERALS
暂未订购
“Flow” Transcranial Direct Current Stimulation (tDCS) for Depression Treatment in a Primary Healthcare General Practice—An Open-Label Cohort Study Measuring Montgomery-Åsberg Depression Rating Scale (MADRS-S) Outcomes
7
作者 Chris Griffiths Harmony Jiang +1 位作者 David Smart Azhar Zafar 《Open Journal of Psychiatry》 2024年第4期386-399,共14页
Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS... Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS has evidence of effectiveness in treating symptoms of depression. Purpose/Aim: This post marketing study evaluated the effect of Flow on depression for primary care general practice patients with depression symptoms. Methods: Open-label patient cohort design with no control group. Inclusion criteria were aged 18 years or over and reporting depression symptoms. Participants self-administered five 30 minute tDCS sessions per week for the first three weeks, and then 3 sessions per week following this. Three, six and ten week assessment with participant self-report measure: Montgomery- Åsberg Depression Rating Scale (MADRS-S). Results: MADRS-S remission rates were between 29% - 30% at three weeks, 33% - 34% at six-weeks and 50% at 10-weeks treatment. There was a significant improvement in MADRS-S with large effect sizes at all time points. Conclusions: Flow tDCS can be delivered through a primary healthcare general practice service and patients will choose to use. Flow tDCS provides an effective depression treatment in addition and as an alternative to antidepressants and psychotherapy. tDCS has evidence as an effective depression treatment, and the widespread availability of tDCS in primary care general practice should be considered. 展开更多
关键词 DEPRESSION Transcranial direct current Stimulation Wellbeing General Practice
在线阅读 下载PDF
Self-Administered “Flow” Transcranial Direct Current Stimulation (tDCS) Depression Treatment in a Crisis Resolution & Home Treatment (CRT) Service: Functioning, and Health-Related Quality of Life Outcomes
8
作者 Chris Griffiths Sherif Abdalla +1 位作者 Mark Mcconnochie Harmony Jiang 《Open Journal of Psychiatry》 2024年第S2期514-527,共14页
Background: Transcranial direct current stimulation (tDCS) has research evidence that it can reduce symptoms of depression. Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a... Background: Transcranial direct current stimulation (tDCS) has research evidence that it can reduce symptoms of depression. Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application that delivers wellbeing behaviour therapy training. Purpose/aim: The purpose of this study was to investigate if Flow can be introduced to a Crisis Resolution & Home Treatment (CRT) service and the impact of Flow in treating depression. The study addresses the questions: 1) “what are the depression reliable improvement and remission rates?” and 2) “can Flow significantly reduce depressive symptoms and improve real world functioning (every-day, social and occupational functioning) and health-related quality of life?”. Methods: An open-label patient cohort design with no control group. Pre-intervention and 6-week follow-up intervention assessments using the participant self-report measures: Patient Health Questionnaire (PHQ-9), Work and Social Adjustment Scale (WSAS), and EuroQol five-dimension (EQ-5D-5L). Participants were 49 CRT patients, 19 males and 30 females, with an age range of 20 to 66 years, and average age of 42 years. Results: PHQ-9 reliable improvement and remission rates were 57.1% and 14.3%. PHQ-9 scores significantly improved, from 23.1 (SD 3.44) to 14.8 (SD 6.82) at 6 weeks, with a large effect size. PHQ-9 suicide/self-harm related question significantly improved from 2.51 (SD 0.77) to 1.08 (SD 1.17), with a large effect size. WSAS scores significantly improved, from 33.6 (SD 5.22) to 21.9 (SD 10.82) at 6 weeks, with a large effect size. EQ-5D-5L results showed significant improvements in the health index score, global assessment of health EQ-VAS from 34.2 (22.26) to 51.6 (24.95), and three EQ-5D-5L dimensions (“self-care”, “usual activity”, and “anxiety/depression”). Conclusion: A CRT service effectively integrated Flow tDCS treatment. Flow was beneficial in terms of improving functioning and quality of life and reducing depression symptoms and thoughts of suicide/self-harm. Flow FL100 tDCS and wellbeing behaviour therapy training could be offered through all CRT services to treat depression, reduce thoughts of suicide/self-harm, enable better functioning, and improve quality of life. 展开更多
关键词 DEPRESSION Quality of Life FUNCTIONING Transcranial direct current Stimulation (tdcS)
在线阅读 下载PDF
Clinical Trial Demonstrates Efficacy of Transcranial Direct Current Stimulation (tDCS) in Improving Pain Management from Post-Laminectomy Syndrome
9
作者 Marilia Capuço Oliveira Fernanda Menezes de Faria +3 位作者 Gerardo Maria de Araújo Filho Ana Carolina Gonçalves Olmos Demosthenes Santana Silva Junior Camila Souza Alves Cosmo 《Pain Studies and Treatment》 2023年第4期27-42,共16页
Chronic pain, a multidimensional experience affecting individuals’ sensory, cognitive, and emotional aspects, significantly impacts their quality of life. Post-laminectomy syndrome, a condition characterized by persi... Chronic pain, a multidimensional experience affecting individuals’ sensory, cognitive, and emotional aspects, significantly impacts their quality of life. Post-laminectomy syndrome, a condition characterized by persistent back pain following spinal surgery, often leads to disability and increased healthcare utilization. Methods: This randomized, controlled, blind clinical trial aimed to investigate the efficacy of Transcranial Direct Current Stimulation (tDCS) in managing pain from post-laminectomy syndrome in patients. Twenty-four participants were assigned to three groups: sham stimulation, active stimulation over primary motor cortex (M1), or stimulation over dorsolateral prefrontal cortex (DLPFC). Stimulation was administered for five consecutive days, 20 minutes per session, using a current of 1.5 mA through 25 cm<sup>2</sup> electrodes. Pain intensity was assessed using Visual Analog Scale (VAS) before, during, and after intervention. Results: An ANOVA model demonstrates significant reduction in pain intensity compared to baseline in VAS, (F(7, 285) = 12.292;p 0.001;Power = 1.000;η2p = 0.534), in tDCS applied to M1, after five days of intervention. After stimulation, a significant improvement was observed in WHOQoL-Bref Quality of life item 1 (p = 0.04), considering statistical significant difference p 0.05. Correlation between the variables: quality of life, depression, anxiety and pain also demonstrates reduction in depression and anxiety according to Beck’s Depression and Anxiety Inventories (BDI and BAI), p 0.05. This effect was not observed in DLPFC stimulation group. Patients who believed they received active stimulation, in sham group, demonstrated potential for effective blinding. Conclusion: The tDCS applied to primary motor cortex effectively improved pain management and psychiatry symptoms in post-laminectomy syndrome patients. The technique’s low cost, ease of use, and high tolerability make it a promising adjuvant therapy for chronic pain conditions like post-laminectomy syndrome. 展开更多
关键词 Non-Invasive Neuromodulation Transcranial direct current Stimulation Post-Laminectomy Syndrome Chronic Pain
暂未订购
Therapeutic efficacy of transcranial direct current stimulation in treating auditory hallucinations in schizophrenia:A meta-analysis 被引量:1
10
作者 Shi-Jia Zou Jin-Nan Shi 《World Journal of Psychiatry》 2025年第3期302-310,共9页
BACKGROUND Schizophrenia is a chronic psychiatric condition with complex symptomatology,including debilitating auditory hallucinations.Transcranial direct current stimulation(tDCS)has been explored as an adjunctive tr... BACKGROUND Schizophrenia is a chronic psychiatric condition with complex symptomatology,including debilitating auditory hallucinations.Transcranial direct current stimulation(tDCS)has been explored as an adjunctive treatment to alleviate such symptoms.AIM To evaluate the therapeutic efficacy of tDCS in schizophrenia.METHODS Adhering to PRISMA guidelines,we systematically searched PubMed,Embase,Web of Science,and the Cochrane Library on September 19,2023,for randomized controlled trials examining the efficacy of tDCS in schizophrenia,with no language or time restrictions.We included studies that compared tDCS with a control condition and reported clinically relevant outcomes.Data extraction and quality assessments were performed by independent evaluators using the Cochrane Collaboration's risk of bias tool.Statistical heterogeneity was evaluated,and a random-effects model was applied due to moderate heterogeneity(I2=41.3%).RESULTS Nine studies comprising 425 participants(tDCS group:219,control group:206)were included.The meta-analysis demonstrated a significant reduction in auditory hallucination scores following tDCS treatment(weighted mean difference:-2.18,95%confidence interval:-4.0 to-0.29,P<0.01).Sensitivity analysis confirmed the robustness of the results,with no significant influence from individual studies.Additionally,publication bias was not detected,supporting the reliability and generalizability of the findings.These results underscore the efficacy of tDCS as a therapeutic intervention for auditory hallucinations in schizophrenia.CONCLUSION tDCS significantly reduces auditory hallucinations in schizophrenia,suggesting its potential as an effective adjunctive treatment for managing this disabling symptom.The findings highlight the practical significance of tDCS in clinical settings,particularly for patients with treatment-resistant auditory hallucinations. 展开更多
关键词 SCHIZOPHRENIA Transcranial direct current stimulation Auditory hallucinations META-ANALYSIS
暂未订购
Refining mechanism of tin–bismuth alloy solidified structure upon applying direct current attached mold 被引量:1
11
作者 Si-yao Liu Ye Zhou +4 位作者 Xin-cheng Miao Qing-he Xiao Rui Guan Xin-gang Ai Sheng-li Li 《Journal of Iron and Steel Research International》 2025年第3期619-628,共10页
Herein,the effect of direct current(DC)attached the mold on refining the microstructure and alleviating the central segregation of a tin–bismuth(Sn–10 wt.%Bi)alloy ingot during the solidification process has been in... Herein,the effect of direct current(DC)attached the mold on refining the microstructure and alleviating the central segregation of a tin–bismuth(Sn–10 wt.%Bi)alloy ingot during the solidification process has been investigated.The experiment used a self-made device,which can achieve the effect of refining the solidified structure and alleviate the segregation of the metal casting.Numerical simulations were performed to calculate the Lorentz force,Joule heating and induced melt vortex flow for the magneto-hydrodynamic case.Our results show that the maximum velocity of the global electro-vortex reached 0.017 m s^(–1).The DC-induced electro-vortex was found to be the primary reason of refining the equiaxed grain and alleviating the segregation of theβ-Sn crystal boundary.The grain refining effect observed in these experiments can be solely attributed to the forced melt flow driven by the Lorentz force.DC field attached the mold can lead to grain refinement and alleviate the segregation of the ingot via a global vortex.The technology can be applied not only to opened molds,but also toward improving the quality in closed molds. 展开更多
关键词 Metal solidification direct current Forced melt flow Grain refinement Segregation alleviation
原文传递
Highly Effective Brushless DC Motor in Which Unidirectional Current Flows in
12
作者 Y. Komatsu T.A. Amarsanaa Y. Araki S.A.K. Zawawi 《Journal of Energy and Power Engineering》 2010年第10期58-64,共7页
Authors developed a highly effective brushless DC motor with a simple operation principle. If the operation principle of the motor is simple, a drive circuit will also become simple and its production cost will be low... Authors developed a highly effective brushless DC motor with a simple operation principle. If the operation principle of the motor is simple, a drive circuit will also become simple and its production cost will be lower. From the above fact, Minato motor was noticed. In this motor, a unidirectional current flows in the electromagnets. In other words, unidirectional windings are used. In this motor, only strong repulsive force is utilized when a permanent magnet of a rotor and an electromagnet of a stator are adjacent. Hence, torque constant becomes higher and the efficiency of the motor is high. However, an effective value of the electromagnetic current increases because a large current flows in a short period. Therefore, copper loss increases and the efficiency of the motor decreases. In order to solve above defects, a new motor is proposed. From the experiment, it is clarified that the efficiency of the proposed motor is higher than that of the commercial motors. 展开更多
关键词 Brushless dc motor Minato motor repulsive force unidirectional current back-EMF.
在线阅读 下载PDF
Calculation of Commutation Failure Overvoltage in High-Voltage Direct Current Transmission Terminal Systems with Grid-Forming Renewable Energy Sources
13
作者 Weibing Xu Bo Yao +5 位作者 Xiangjun Quan Xunyou Zhang Ning Zou Shuo Liu Jia Wang Jiansuo Zhang 《Energy Engineering》 2025年第10期4225-4243,共19页
The integration of large-scale new energy and high-capacity DC transmission leads to a reduction in system inertia.Grid-forming renewable energy sources(GF-RES)has a significant improvement effect on system inertia.Co... The integration of large-scale new energy and high-capacity DC transmission leads to a reduction in system inertia.Grid-forming renewable energy sources(GF-RES)has a significant improvement effect on system inertia.Commutation failure faults may cause a short-term reactive power surplus at the sending end and trigger transient overvoltage,threatening the safe and stable operation of the power grid.However,there is a lack of research on the calculation method of transient overvoltage caused by commutation failure in high-voltage DC transmission systems with grid-forming renewable energy sources integration.Based on the existing equivalent model of highvoltage DC transmission systems at the sending end,this paper proposes to construct a model of the high-voltage DC transmission system at the sending end with grid-forming renewable energy sources.The paper first clarifies the mechanism of overvoltage generation,then considers the reactive power droop control characteristics of GF-RES,and derives the transient voltage calculation model of theDC transmission system with GF-RES integration.It also proposes a calculation method for transient overvoltage at the sending-end converter bus with GF-RES integration.Based on the PSCAD/EMTDC simulation platform,this paper builds an experimental simulation model.By constructing three different experimental scenarios,the accuracy and effectiveness of the proposed transient overvoltage calculation method are verified,with a calculation error within 5%.At the same time,this paper quantitatively analyzes the impact of grid strength,new energy proportion,and rated transmission power on transient overvoltage from three different perspectives. 展开更多
关键词 Grid-forming renewable energy commutation failure transient overvoltage high-voltage direct current sending-end direct current system
在线阅读 下载PDF
Sub-forum on standardization of new energy and direct-current diversified applications held
14
作者 Cao Xinxin 《China Standardization》 2025年第5期52-53,共2页
The sub-forum on standardization of new energy and direct-current diversified applications was held on July 9,which gathered leaders and experts to discuss how to thoroughly implement the national green power direct c... The sub-forum on standardization of new energy and direct-current diversified applications was held on July 9,which gathered leaders and experts to discuss how to thoroughly implement the national green power direct connection policy proposed in the transformation of the energy landscape,pool wisdom to tackle bottlenecks in the industrialization of DC technology,and leverage the role of standardization in coordinating and regulating the diversified applications of DC technology.It was designed to promote the establishment of a collaborative,open,and advanced global standards system for DC technology. 展开更多
关键词 transformation energy landscapepool wisdom tackle bottlenecks direct current technology green power coordinating regulating diversified applications new energy global standards system dc technologyand STANDARDIZATION
原文传递
Short-term effects of transcranial direct current stimulation on pain sensitivity, emotional and cognitive processes in non-suicidal self-injury: a randomised controlled trial
15
作者 Chang Lei Diyang Qu +4 位作者 Dennis Chong Yangyang Yi Weijian Wu Yiheng Tu Runsen Chen 《General Psychiatry》 2025年第3期176-185,共10页
Background Pain sensitivity is critical for preventing non-suicidal self-injury(NSSI)behaviours;however,individuals engaging in such behaviours often exhibit decreased pain sensitivity,which may undermine this natural... Background Pain sensitivity is critical for preventing non-suicidal self-injury(NSSI)behaviours;however,individuals engaging in such behaviours often exhibit decreased pain sensitivity,which may undermine this natural safeguard.The dorsolateral prefrontal cortex(DLPFC)is a key region involved in pain regulation,and recent approaches using transcranial direct current stimulation(tDCS)to target the DLPFC have shown potential for modulating pain processing and restoring normal pain perception for individuals engaging in NSSI behaviours.Aims This study aimed to explore the immediate and short-term effects of a single session of tDCS on pain sensitivity in individuals with NSSI,as well as its secondary effects on mood and NSSI-related factors.Methods In this randomised,double-blind,parallel,sham-controlled clinical trial,participants with a history of NSSI were randomly assigned to receive either active or sham tDCS.The intervention consisted of a single 20 min tDCS session targeting the left DLPFC.The primary outcome was pain sensitivity,measured by the pressure pain threshold(PPT)and heat pain score(HPS).Secondary and additional outcomes included NSSI urges,NSSI resistance,self-efficacy in resisting NSSI,mood-related variables and exploratory cognitive-affective processes such as rumination,self-criticism and self-perceived pain sensitivity,assessed at baseline,immediately post-intervention,and at 24 hours,1 week and 2 weeks follow-ups.Results For the primary outcomes,no significant differences between groups were observed for pain sensitivity(PPT,padj=0.812;HPS,padj=0.608).However,an exploratory sensitivity analysis treating each trial as an individual observation revealed a significant effect on HPS(padj=0.036).For the secondary and additional outcomes,although there were initial improvements in joyful feelings and reductions in negative affect at 2 weeks post-intervention,these effects did not remain significant after multiple comparison corrections.Notably,reductions in rumination were statistically significant at both 1-week and 2-week follow-ups(1 week,p_(adj)=0.040;2 weeks,p_(adj)=0.042).There were no significant effects on NSSI urges,NSSI resistance,self-efficacy in resisting NSSI or self-criticism.Conclusions A single session of tDCS over the left DLPFC did not produce significant changes in pain sensitivity in individuals with NSSI.A sensitivity analysis indicated an effect on heat pain sensitivity,possibly reflecting changes in brain activity,warranting confirmation through neuroimaging.These findings suggest that tDCS warrants further investigation for its potential to influence pain-related cognitive-affective processes in individuals with NSSI. 展开更多
关键词 Non Suicidal Self Injury MOOD Dorsolateral Prefrontal Cortex modulating pain processing Transcranial direct current Stimulation Cognitive Processes dorsolateral prefrontal cortex dlpfc transcranial direct current stimulation tdcs
暂未订购
Dark current investigation of a direct-current and superconducting radio-frequency combined photocathode gun
16
作者 Tian-Yi Li Hao-Yan Jia +6 位作者 Jun-Tao Liu Lin Lin Fei Jiao Li-Wen Feng Sheng-Wen Quan Jing-Yi Li Sen-Lin Huang 《Nuclear Science and Techniques》 2025年第8期49-57,共9页
Low dark current photocathode guns are highly desired for high-brightness continuous-wave operations.Direct-current superconducting radio-frequency(DC-SRF)gun,a hybrid photocathode gun combining a DC gap and an SRF ca... Low dark current photocathode guns are highly desired for high-brightness continuous-wave operations.Direct-current superconducting radio-frequency(DC-SRF)gun,a hybrid photocathode gun combining a DC gap and an SRF cavity,effectively isolates the photocathode from the SRF cavity and offers significant advantages in terms of minimizing dark current levels.This paper presents an in-depth analysis of the dark current of a newly developed high-brightness DC-SRF photocathode gun(DC-SRF-Ⅱ gun).Particularly,a systematic experimental investigation of the dark current was conducted,and a comprehensive understanding of its formation was achieved through compliant simulations and measurements.Additionally,measures for attaining sub-nanoampere dark currents in the DC-SRF-Ⅱ gun are presented,including design considerations,cavity processing,assembly,and conditioning.The findings of this study establish a strong foundation for achieving high-performance operation of the DC-SRF-Ⅱ gun and provide a valuable reference for other photocathode guns. 展开更多
关键词 Dark current Photocathode gun dc conditioning RF conditioning Tracking simulation
在线阅读 下载PDF
Effect of pulse current and its application direction on the size effect of nanocrystalline nickel foil
17
作者 WANG Yi-yan LI Chao +2 位作者 CHEN Zi-shuai DU Jin-yang LI Feng 《Journal of Central South University》 2025年第7期2416-2431,共16页
In order to gain a deeper understanding of the effect of pulsed current on the mechanical properties and size effect of nanocrystalline Ni foils,nanocrystalline Ni foils with different grain thickness-to-grain size ra... In order to gain a deeper understanding of the effect of pulsed current on the mechanical properties and size effect of nanocrystalline Ni foils,nanocrystalline Ni foils with different grain thickness-to-grain size ratios(λ)were prepared using pulsed electrodeposition in this paper and unidirectional tensile experiments were carried out at room temperature with different currents and their applied directions.The experimental results show that the nanocrystalline Ni foil produces an obvious electroplasticity effect after applying the current field,and when 300<λ<1100,the current weakens the size effect of nanocrystalline Ni foils to a certain extent,and the angle between the current direction and the deformation direction also affects the mechanical response of nanocrystalline Ni foils,and when the angle between the current direction and the deformation direction is 0°,electroplasticity effect is the best,and the current has the most significant effect of abating the size effect of the material.The mechanism of unidirectional tensile deformation of nanocrystalline Ni foils under the effect of pulsed current was analyzed using TEM and TKD.It was found that the applied pulse current increased the activity of the nanocrystalline boundaries,promoted the movement of dislocations,and reduced the tendency of dislocation entanglement.The higher the peak current density and the smaller the angle between the direction of the current and the direction of deformation,the smaller the grain boundary orientation difference,the more dispersed the grain orientation,and the lower the density of geometrically necessary dislocations(GND)in the deformed nanocrystalline foil,the more significant the effect on material plasticity improvement. 展开更多
关键词 nanocrystalline Ni foil size effect electroplasticity effect current direction
在线阅读 下载PDF
Correction:Impact of twice-a-day transcranial direct current stimulation interuention on cognitive function and motor cortex plasticity in patients with Alzheimer's disease
18
《General Psychiatry》 2025年第5期415-415,共1页
An unauthorised version of the Chinese MMSE was used in this article by the authors without permission from the copyright owner,PAR.Necessary permission has now been retrospectively obtained from PAR.The MMSE is a cop... An unauthorised version of the Chinese MMSE was used in this article by the authors without permission from the copyright owner,PAR.Necessary permission has now been retrospectively obtained from PAR.The MMSE is a copyrighted instrument and may not be used or reproduced in whole or in part,in any form or language,or by any means without the written permission of PAR(www.parinc.com). 展开更多
关键词 transcranial direct current stimulation motor cortex plasticity COPYRIGHT cognitive function retrospective permission unauthorized version alzheimer's disease
暂未订购
Effect of preoperative transcranial direct current stimulation on postoperative delirium in elderly patients following laparoscopic surgery
19
作者 Xi Yang Yu-Fei Wei +4 位作者 Chen-Hui Ye Wen-Di Tian Xue-Yao Li Ye-Ju Hu Li-Ping Chen 《World Journal of Psychiatry》 2025年第10期239-249,共11页
BACKGROUND Postoperative delirium(POD),an acute neuropsychiatric complication in elderly surgical patients,manifests as attention and cognitive disturbances that may last 24-72 hours after surgery,potentially progress... BACKGROUND Postoperative delirium(POD),an acute neuropsychiatric complication in elderly surgical patients,manifests as attention and cognitive disturbances that may last 24-72 hours after surgery,potentially progressing to dementia.Transcranial direct current stimulation(tDCS),a non-invasive neuromodulation technique,enhances cortical excitability and cognitive function by modulating brain networks and synaptic plasticity.Elderly patients undergoing major laparoscopic surgery face elevated POD risks due to prolonged anesthesia and pneumoperitoneum-induced cerebral hypoperfusion.This study investigates whether pre-anesthesia tDCS can reduce POD incidence in this population.AIM To investigate the effect of preoperative tDCS on reducing the incidence of POD in elderly patients undergoing major laparoscopic surgery.METHODS In this study,we enrolled 220 elderly patients who underwent major laparoscopic surgery between April 2024 and December 2024.Patients were randomly assigned to the active-tDCS(group A)and sham-tDCS(group S)groups.A single session of tDCS or sham stimulation was administered 30 minutes before anesthesia induction.The primary outcome was the incidence of POD during within 3 days postoperatively.RESULTS A total of 201 patients were included in the final analysis,with 100 patients in group A and 101 in group S.The incidence of POD within 3 days postoperatively was 7.0%in group A,which was significantly lower than 22.8%in group S.On postoperative day 1,the Self-Rating Anxiety Scale and Self-Rating Depression Scale scores significantly differed between the two groups,but the pain scores showed no significant difference.CONCLUSION A single session of preoperative tDCS can reduce the incidence of POD in elderly patients undergoing major laparoscopic surgery and can also reduce postoperative anxiety and depression in these patients. 展开更多
关键词 Transcranial direct current stimulation Postoperative delirium COGNITION Laparoscopic surgery Randomized controlled trial
暂未订购
Simulation-based parameter optimization and development of a split-core fluxgate DC current sensor
20
作者 YANG Dechao SHI Junjiang +3 位作者 ZHAO Zhengang HOU Yingjie YANG Kuisong JIANG Xin 《Journal of Measurement Science and Instrumentation》 2025年第4期588-602,共15页
Fluxgate current sensors(FGCSs)are increasingly employed in power systems due to their high-precision characteristics,yet their measurement flexibility remains constrained by conventional closed-core designs.To addres... Fluxgate current sensors(FGCSs)are increasingly employed in power systems due to their high-precision characteristics,yet their measurement flexibility remains constrained by conventional closed-core designs.To address this limitation,we proposed a split-core sensor structure comprising four magnetic core strips,which achieved non-intrusive current measurement while maintaining detection accuracy.An analytical model of the induced electromotive force was established based on the probe’s geometric configuration,followed by finite element simulations to optimize key parameters including core radius,core width,excitation coil turns,and sensing coil configuration.A complete prototype integrating the measurement probe,excitation circuit,and signal processing circuitry was developed and experimentally validated.The experimental results show a sensitivity of 0.1099 V/A,a hysteresis error of 0.559%,and a repeatability error of 1.574%over a measurement range of±10 A.After polynomial fitting-based error compensation,the nonlinearity error was reduced to 0.208%,achieving performance comparable to closed-core sensors.This work provided a practical solution for applications demanding both high measurement accuracy and installation flexibility. 展开更多
关键词 fluxgate current sensor second harmonic method finite element simulation parameter optimization circuit design dc measurement
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部