<div style="text-align:justify;"> <strong>Background</strong>: <span "="">Insulin resistance (IR) is the backbone of cardiovascular diseases (CVDs). The latter are the ...<div style="text-align:justify;"> <strong>Background</strong>: <span "="">Insulin resistance (IR) is the backbone of cardiovascular diseases (CVDs). The latter are the most common non-communicable diseases globally. Diet is an important determinant of CVDs. The link between diet and cardiovascular health could be explained by an association between diet pattern and IR. <b>Aims</b>: To investigate the association between salt and specific food consumption as well as different diet patterns (Mediterranean, westernized, and intermediate dietary patterns) with HOMAIR as a surrogate marker of IR, and fasting insulin in Black, sub-Saharan essential hypertensive</span> patient<span "="">s. <b>Methods</b>: The multicentric, cross-sectional analysis involved 77 Congolese Black hypertensive participants with no history of cardiovascular disease. Daily sodium chloride intake (NaCl g/24h) was estimated from 24-hour urine collection. Dietary behaviours were evaluated through a semi-quantitative food frequency questionnaire (FFQ). Homeostatic model assessment of insulin resistance (HOMAIR) ≥ 2.5 was used as surrogate marker of IR. <b>Results</b>: A decrease in weekly consumption of fruits, vegetables and fish would significantly explain an increase of 29% (r = 0.292;p = 0.010), 24% (r = 0.242;p = 0.034) and 23% (r = 0.226;p = 0.048) of the value of HOMAIR respectively. In contrast, an increase in daily sodium chloride intake was associated with 28% (r = 0.283, p = 0.027) of the increase in HOMAIR. Also, a decrease in the average weekly consumption of fruit, vegetables and fish would significantly explain an increase of 25% (r = 0.247;p = 0.030), 30% (r = 0.302;p = 0.008) and 31% (r = 0.313;p = 0.006) of fasting insulin. In contrast, an increase in red meat consumption was associated with a 26% increase (r = 0.257, p = 0.024) in fasting insulin. In multivariable adjusted analysis 45% of variation in fasting insulin (R<sup>2</sup> = 0.452;overall p = 0.005) were explained by fruits, vegetables and fish consumption. 38% of variation in HOMAIR (R<sup>2</sup> = 0.379;overall p = 0.047) were explained by fruits and vegetable consumption and daily sodium chloride intake (NaCl g/24h). <b>Conclusions: </b>In hypertensive Black sub-Saharan Africans, Salt intake and westernized diet seem to promote insulin resistance whereas Mediterranean diet, fruits, vegetables and fish consumption enhance insulin sensitivity.</span> </div>展开更多
Objective: to study the effect of nutrition knowledge, attitude and dietary behavior of medical students before and after clinical nutrition teaching, in order to provide favorable basis for nutrition education of med...Objective: to study the effect of nutrition knowledge, attitude and dietary behavior of medical students before and after clinical nutrition teaching, in order to provide favorable basis for nutrition education of medical students. Methods: 300 students were selected for routine clinical teaching in the first half of 2021 and clinical nutrition teaching in the second half of 2021. After that, questionnaires were used to understand the medical students knowledge, attitude towards nutrition and dietary behavior, and to analyze the effect before and after clinical nutrition teaching. Results: after clinical nutrition teaching, the students awareness rate of nutrition knowledge was significantly higher than before nutrition education, the difference was statistically significant (P < 0.05). After receiving the teaching of clinical nutrition, the students pay close attention to their own nutritional status, which is manifested by the learning attitude of eager to learn nutritional knowledge. Among them, 279 (93.0%) students express that nutritional knowledge is very important, 297 (99.0%) students express that they are willing to take the initiative to learn more nutritional knowledge, and 279 (93.0%) students express that regular eating of snacks will affect their health status. 294 cases (98.0%) of students said it was very important to have breakfast in the morning. However, there were still 180 cases (60.0%) of students who preferred to sleep late rather than eat breakfast early. After the teaching of clinical nutrition, the rates of breakfast, body weight, regular and quantitative meals, fresh vegetables, fruits, bean products, dairy products, nuts, seafood, meat and eggs, carbonated drinks, western fast food, sweets, fried foods, preserved fruits, puffed foods, diet and supper were significantly higher than before (p < 0.05). Conclusion: after receiving clinical nutrition teaching, medical students nutrition knowledge, attitude and eating behavior have been significantly improved, and there is a high probability to control their own diet by using good nutrition knowledge and positive eating attitude, so as to improve their health. It has obvious application significance and is worthy of promotion.展开更多
The aim of this study was to investigate the relationship among body image perceptions, a desire for thinness, and dieting behavior in young females in Japan. The subjects were 302 Japanese female university students ...The aim of this study was to investigate the relationship among body image perceptions, a desire for thinness, and dieting behavior in young females in Japan. The subjects were 302 Japanese female university students (age 19.9 ± 1.4 years). An anonymous, self-administered questionnaire survey was conducted between July and August 2011. The questionnaire clarified the subjects’ physical status, perception about personal body shape, desired body shape, the time frame when they first thought about body shape dieting, exercise habits, and eating behaviors. The results revealed that many of the underweight or normal weight subjects perceived themselves as obese, and often the reasons for the perception of obesity were comparisons with others or with themselves in the past. The scores of EAT-26 in those who perceived themselves as obese were higher than the scores in those who did not. Those who perceived themselves as obese had a desire to become slim, were concerned about body shape at an early age, were concerned about dieting, had dieting experience, and were willing to increase daily exercise. These results indicated that incorrect perceptions about body shape have connection to a desire for thinness and dieting behavior.展开更多
Diet is an important health factor and it has been recently associated with neurodegenerative diseases and cognitive decline. Here it was investigated the effect of fatty acid or cholesterol rich diets with the possib...Diet is an important health factor and it has been recently associated with neurodegenerative diseases and cognitive decline. Here it was investigated the effect of fatty acid or cholesterol rich diets with the possible acceleration of the biological decline in adult hippocampal neurogenesis associated with aging in middle-age rats, and its impact on anxiety and memory function. It was found that a diet of 10 weeks with saturated fatty acids and cholesterol has a detrimental effect on memory function, exerts like-anxiety behavior and diminishes the presence of new generated neurons in the hippocampus in six months old rats.展开更多
Emergence of tablet computers has led to interest in their use to impact health-related behaviors of users. However, little is known regarding which devices are most effective for changing these behaviors, and whether...Emergence of tablet computers has led to interest in their use to impact health-related behaviors of users. However, little is known regarding which devices are most effective for changing these behaviors, and whether or not these devices or accompanying applications (apps) are feasible or desired vehicles for behavior change. Four focus groups were conducted with students from a Western university who were given iPads to download diet-related apps. Participants were asked questions about preferences regarding iPad functionality, app functionality, and the likelihood of using apps and iPads for facilitating diet-related behavior change in the future. Two key themes emerged from focus group discussions on diet-related apps for iPads and their usefulness to facilitate behavior change. The first theme, lack of iPad practicality, contained three subthemes: inconvenient mid-way technology, internet access barriers, and smart-phone preference. The second theme that emerged was attitudes towards apps in general. Three subthemes were identified under the second theme: too intensive;positive functions not specific to iPads;and lack of reliable/trustworthy information. This paper is the first, to this author’s knowledge, to report the use of qualitative methods to study the practicality of using apps and iPads in changing dietrelated behaviors. Early generations of iPads may not be effective devices for facilitating behavior change among college students;and diet-related apps seem to have poor functionality that lead to cessation of use.展开更多
We have previously shown that induction of ketosis by ketogenic diet(KD)conveyed neuroprotection following spinal cord injury in rodent models,however,clinical translation may be limited by the slow raise of ketone le...We have previously shown that induction of ketosis by ketogenic diet(KD)conveyed neuroprotection following spinal cord injury in rodent models,however,clinical translation may be limited by the slow raise of ketone levels when applying KD in the acute post-injury period.Thus we investigated the use of exogenous ketone supplementation(ketone sodium,KS)combined with ketogenic diet as a means rapidly inducing a metabolic state of ketosis following spinal cord injury in adult rats.In uninjured rats,ketone levels increased more rapidly than those in rats with KD alone and peaked at higher levels than we previously demonstrated for the KD in models of spinal cord injury.However,ketone levels in KD+KS treated rats with SCI did not exceed the previously observed levels in rats treated with KD alone.We still demonstrated neuroprotective effects of KD+KS treatment that extend our previous neuroprotective observations with KD only.The results showed increased neuronal and axonal sparing in the dorsal corticospinal tract.Also,better performance of forelimb motor abilities were observed on the Montoya staircase(for testing food pellets reaching)at 4 and 6 weeks post-injury and rearing in a cylinder(for testing forelimb usage)at 6 and 8 weeks post-injury.Taken together,the findings of this study add to the growing body of work demonstrating the potential benefits of inducing ketosis following neurotrauma.Ketone salt combined with a ketogenic diet gavage in rats with acute spinal cord injury can rapidly increase ketone body levels in the blood and promote motor function recovery.This study was approved by the Animal Care Committee of the University of British Columbia(protocol No.A14-350)on August 31,2015.展开更多
文摘<div style="text-align:justify;"> <strong>Background</strong>: <span "="">Insulin resistance (IR) is the backbone of cardiovascular diseases (CVDs). The latter are the most common non-communicable diseases globally. Diet is an important determinant of CVDs. The link between diet and cardiovascular health could be explained by an association between diet pattern and IR. <b>Aims</b>: To investigate the association between salt and specific food consumption as well as different diet patterns (Mediterranean, westernized, and intermediate dietary patterns) with HOMAIR as a surrogate marker of IR, and fasting insulin in Black, sub-Saharan essential hypertensive</span> patient<span "="">s. <b>Methods</b>: The multicentric, cross-sectional analysis involved 77 Congolese Black hypertensive participants with no history of cardiovascular disease. Daily sodium chloride intake (NaCl g/24h) was estimated from 24-hour urine collection. Dietary behaviours were evaluated through a semi-quantitative food frequency questionnaire (FFQ). Homeostatic model assessment of insulin resistance (HOMAIR) ≥ 2.5 was used as surrogate marker of IR. <b>Results</b>: A decrease in weekly consumption of fruits, vegetables and fish would significantly explain an increase of 29% (r = 0.292;p = 0.010), 24% (r = 0.242;p = 0.034) and 23% (r = 0.226;p = 0.048) of the value of HOMAIR respectively. In contrast, an increase in daily sodium chloride intake was associated with 28% (r = 0.283, p = 0.027) of the increase in HOMAIR. Also, a decrease in the average weekly consumption of fruit, vegetables and fish would significantly explain an increase of 25% (r = 0.247;p = 0.030), 30% (r = 0.302;p = 0.008) and 31% (r = 0.313;p = 0.006) of fasting insulin. In contrast, an increase in red meat consumption was associated with a 26% increase (r = 0.257, p = 0.024) in fasting insulin. In multivariable adjusted analysis 45% of variation in fasting insulin (R<sup>2</sup> = 0.452;overall p = 0.005) were explained by fruits, vegetables and fish consumption. 38% of variation in HOMAIR (R<sup>2</sup> = 0.379;overall p = 0.047) were explained by fruits and vegetable consumption and daily sodium chloride intake (NaCl g/24h). <b>Conclusions: </b>In hypertensive Black sub-Saharan Africans, Salt intake and westernized diet seem to promote insulin resistance whereas Mediterranean diet, fruits, vegetables and fish consumption enhance insulin sensitivity.</span> </div>
文摘Objective: to study the effect of nutrition knowledge, attitude and dietary behavior of medical students before and after clinical nutrition teaching, in order to provide favorable basis for nutrition education of medical students. Methods: 300 students were selected for routine clinical teaching in the first half of 2021 and clinical nutrition teaching in the second half of 2021. After that, questionnaires were used to understand the medical students knowledge, attitude towards nutrition and dietary behavior, and to analyze the effect before and after clinical nutrition teaching. Results: after clinical nutrition teaching, the students awareness rate of nutrition knowledge was significantly higher than before nutrition education, the difference was statistically significant (P < 0.05). After receiving the teaching of clinical nutrition, the students pay close attention to their own nutritional status, which is manifested by the learning attitude of eager to learn nutritional knowledge. Among them, 279 (93.0%) students express that nutritional knowledge is very important, 297 (99.0%) students express that they are willing to take the initiative to learn more nutritional knowledge, and 279 (93.0%) students express that regular eating of snacks will affect their health status. 294 cases (98.0%) of students said it was very important to have breakfast in the morning. However, there were still 180 cases (60.0%) of students who preferred to sleep late rather than eat breakfast early. After the teaching of clinical nutrition, the rates of breakfast, body weight, regular and quantitative meals, fresh vegetables, fruits, bean products, dairy products, nuts, seafood, meat and eggs, carbonated drinks, western fast food, sweets, fried foods, preserved fruits, puffed foods, diet and supper were significantly higher than before (p < 0.05). Conclusion: after receiving clinical nutrition teaching, medical students nutrition knowledge, attitude and eating behavior have been significantly improved, and there is a high probability to control their own diet by using good nutrition knowledge and positive eating attitude, so as to improve their health. It has obvious application significance and is worthy of promotion.
文摘The aim of this study was to investigate the relationship among body image perceptions, a desire for thinness, and dieting behavior in young females in Japan. The subjects were 302 Japanese female university students (age 19.9 ± 1.4 years). An anonymous, self-administered questionnaire survey was conducted between July and August 2011. The questionnaire clarified the subjects’ physical status, perception about personal body shape, desired body shape, the time frame when they first thought about body shape dieting, exercise habits, and eating behaviors. The results revealed that many of the underweight or normal weight subjects perceived themselves as obese, and often the reasons for the perception of obesity were comparisons with others or with themselves in the past. The scores of EAT-26 in those who perceived themselves as obese were higher than the scores in those who did not. Those who perceived themselves as obese had a desire to become slim, were concerned about body shape at an early age, were concerned about dieting, had dieting experience, and were willing to increase daily exercise. These results indicated that incorrect perceptions about body shape have connection to a desire for thinness and dieting behavior.
文摘Diet is an important health factor and it has been recently associated with neurodegenerative diseases and cognitive decline. Here it was investigated the effect of fatty acid or cholesterol rich diets with the possible acceleration of the biological decline in adult hippocampal neurogenesis associated with aging in middle-age rats, and its impact on anxiety and memory function. It was found that a diet of 10 weeks with saturated fatty acids and cholesterol has a detrimental effect on memory function, exerts like-anxiety behavior and diminishes the presence of new generated neurons in the hippocampus in six months old rats.
文摘Emergence of tablet computers has led to interest in their use to impact health-related behaviors of users. However, little is known regarding which devices are most effective for changing these behaviors, and whether or not these devices or accompanying applications (apps) are feasible or desired vehicles for behavior change. Four focus groups were conducted with students from a Western university who were given iPads to download diet-related apps. Participants were asked questions about preferences regarding iPad functionality, app functionality, and the likelihood of using apps and iPads for facilitating diet-related behavior change in the future. Two key themes emerged from focus group discussions on diet-related apps for iPads and their usefulness to facilitate behavior change. The first theme, lack of iPad practicality, contained three subthemes: inconvenient mid-way technology, internet access barriers, and smart-phone preference. The second theme that emerged was attitudes towards apps in general. Three subthemes were identified under the second theme: too intensive;positive functions not specific to iPads;and lack of reliable/trustworthy information. This paper is the first, to this author’s knowledge, to report the use of qualitative methods to study the practicality of using apps and iPads in changing dietrelated behaviors. Early generations of iPads may not be effective devices for facilitating behavior change among college students;and diet-related apps seem to have poor functionality that lead to cessation of use.
基金supported by the Craig Neilsen Foundation(to WT)the Canadian Institutes for Health Research(to WT)+2 种基金supported by the China Scholarship Council(No.201508500102)a visiting trainee stipend from the Blusson Integrated Cure Partnershipthe John and Penny Ryan British Columbia Leadership Chair in Spinal Cord Research funded in part by the Rick Hansen Foundation
文摘We have previously shown that induction of ketosis by ketogenic diet(KD)conveyed neuroprotection following spinal cord injury in rodent models,however,clinical translation may be limited by the slow raise of ketone levels when applying KD in the acute post-injury period.Thus we investigated the use of exogenous ketone supplementation(ketone sodium,KS)combined with ketogenic diet as a means rapidly inducing a metabolic state of ketosis following spinal cord injury in adult rats.In uninjured rats,ketone levels increased more rapidly than those in rats with KD alone and peaked at higher levels than we previously demonstrated for the KD in models of spinal cord injury.However,ketone levels in KD+KS treated rats with SCI did not exceed the previously observed levels in rats treated with KD alone.We still demonstrated neuroprotective effects of KD+KS treatment that extend our previous neuroprotective observations with KD only.The results showed increased neuronal and axonal sparing in the dorsal corticospinal tract.Also,better performance of forelimb motor abilities were observed on the Montoya staircase(for testing food pellets reaching)at 4 and 6 weeks post-injury and rearing in a cylinder(for testing forelimb usage)at 6 and 8 weeks post-injury.Taken together,the findings of this study add to the growing body of work demonstrating the potential benefits of inducing ketosis following neurotrauma.Ketone salt combined with a ketogenic diet gavage in rats with acute spinal cord injury can rapidly increase ketone body levels in the blood and promote motor function recovery.This study was approved by the Animal Care Committee of the University of British Columbia(protocol No.A14-350)on August 31,2015.
