The complexity of living environment system demands higher requirements for the sensitivity and selectivity of the probe.Therefore,it is of great importance to develop a universal strategy for highperformance probe op...The complexity of living environment system demands higher requirements for the sensitivity and selectivity of the probe.Therefore,it is of great importance to develop a universal strategy for highperformance probe optimization.Herein,we propose a novel“Enrichment-enhanced Detection”strategy and use carbon dots-dopamine detection system as a representative model to evaluate its feasibility.The composite probe carbon dots (CDs)-encapsulated in glycol-chitosan (GC)(i.e.,CDs@GC) was obtained by simply mixing GC and CDs through noncovalent interactions,including electrostatic interactions and hydrogen bonding.Dopamine (DA) could be detected through internal filter effect (IFE)-induced quenching of CDs.In the case of CDs@GC,noncovalent interactions (electrostatic interactions) between GC and the formed quinone (oxide of DA) could selectively extract and enrich the local concentration of DA,thus effectively improving the sensitivity and selectivity of the sensing system.The nanosensor had a low detection limit of 3.7 nmol/L,which was a 12-fold sensitivity improvement compared to the bare CDs probes with similar fluorescent profiles,proving the feasibility of the“Enrichment-enhanced Detection”strategy.Further,to examine this theory in real case,we designed a highly portable sensing platform to realize visual determination of DA.Overall,our work introduces a new strategy for accurately detecting DA and provides valuable insights for the universal design and optimization of superior nanoprobes.展开更多
Room-temperature(RT)terahertz(THz)detection finds widespread applications in security inspection,communication,biomedical imaging,and scientific research.However,the state-of-the-art detection strategies are still lim...Room-temperature(RT)terahertz(THz)detection finds widespread applications in security inspection,communication,biomedical imaging,and scientific research.However,the state-of-the-art detection strategies are still limited by issues such as low sensitivity,narrow response range,slow response speed,complex fabrication techniques,and difficulties in scaling up to large arrays.Here,we present a high-sensitivity,broadband-response,and high-speed RT THz detection strategy by utilizing a deep subwavelength metal–semiconductor–metal(MSM)structure.The spontaneously formed 2-dimensional electron gas(2DEG)at the CdTe/PbTe interface provides a superior transport channel characterized by high carrier concentration,low scattering,and high mobility.The synergy of the electromagnetic induced well effect formed in the MSM structure,and the efficient and rapid transport capabilities of the 2DEG channel give rise to an impressive performance improvement.The proposed 2DEG photodetector exhibits a broad frequency range from 22 to 519 GHz,an ultralow noise equivalent power of 3.0×10^(−14)W Hz^(−1/2)at 166 GHz,and a short response time of 6.7μs.This work provides an effective route for the development of high-performance RT THz detection strategies,paving the way for enhanced THz technology applications.展开更多
Mercury ion(Hg^(2+)),known as one of the highly toxic and soluble heavy metal ions,is causing serious environmental pollution and irreversible damage to the health.It is urgent to develop some rapid and ultrasensitive...Mercury ion(Hg^(2+)),known as one of the highly toxic and soluble heavy metal ions,is causing serious environmental pollution and irreversible damage to the health.It is urgent to develop some rapid and ultrasensitive methods for detecting trace mercury ions in the environment especially drink water.Surface-enhanced Raman scattering(SERS)is considered as a novel and powerful optical analysis technique since it has the significant advantages of ultra-sensitivity and high specificity.In recent years,the SERS technique and its application in the detection of Hg^(2+)have become more prevalent and compelling.This review provides an overall survey of the development of SERS-based Hg^(2+)detections and presents a summary relating to the basic principles,detection strategies,recent advances and current challenges of SERS for Hg^(2+)detections.展开更多
基金the financial support from the National Natural Science Foundation of China(No.21904007)the Fundamental Research Funds for the Central Universities(China,No.2412022QD008)+1 种基金the Jilin Provincial Department of Education(China),the Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province(China)the Analysis and Testing Center of Northeast Normal University(China)。
文摘The complexity of living environment system demands higher requirements for the sensitivity and selectivity of the probe.Therefore,it is of great importance to develop a universal strategy for highperformance probe optimization.Herein,we propose a novel“Enrichment-enhanced Detection”strategy and use carbon dots-dopamine detection system as a representative model to evaluate its feasibility.The composite probe carbon dots (CDs)-encapsulated in glycol-chitosan (GC)(i.e.,CDs@GC) was obtained by simply mixing GC and CDs through noncovalent interactions,including electrostatic interactions and hydrogen bonding.Dopamine (DA) could be detected through internal filter effect (IFE)-induced quenching of CDs.In the case of CDs@GC,noncovalent interactions (electrostatic interactions) between GC and the formed quinone (oxide of DA) could selectively extract and enrich the local concentration of DA,thus effectively improving the sensitivity and selectivity of the sensing system.The nanosensor had a low detection limit of 3.7 nmol/L,which was a 12-fold sensitivity improvement compared to the bare CDs probes with similar fluorescent profiles,proving the feasibility of the“Enrichment-enhanced Detection”strategy.Further,to examine this theory in real case,we designed a highly portable sensing platform to realize visual determination of DA.Overall,our work introduces a new strategy for accurately detecting DA and provides valuable insights for the universal design and optimization of superior nanoprobes.
基金supported by the National Natural Science Foundation of China(11933006,61805060,U2141240,and 62175045)National Key Research and Development Project of China(2023YFB2806700)+5 种基金Zhejiang Provincial Natural Science Foundation of China(LGF21F050001)Hangzhou Science and Technology Bureau of Zhejiang Province(TD2020002)Hangzhou Key Research and Development Program(2024SZD1A39)Research Funds of Hangzhou Institute for Advanced Study(B02006C019019 and 2022ZZ01007)Zhejiang Provincial Natural Science Foundation of China(no.LD25F040001)Hangzhou Joint Fund of the Zhejiang Provincial Natural Science Foundation of China(no.LHZQN25F050001).
文摘Room-temperature(RT)terahertz(THz)detection finds widespread applications in security inspection,communication,biomedical imaging,and scientific research.However,the state-of-the-art detection strategies are still limited by issues such as low sensitivity,narrow response range,slow response speed,complex fabrication techniques,and difficulties in scaling up to large arrays.Here,we present a high-sensitivity,broadband-response,and high-speed RT THz detection strategy by utilizing a deep subwavelength metal–semiconductor–metal(MSM)structure.The spontaneously formed 2-dimensional electron gas(2DEG)at the CdTe/PbTe interface provides a superior transport channel characterized by high carrier concentration,low scattering,and high mobility.The synergy of the electromagnetic induced well effect formed in the MSM structure,and the efficient and rapid transport capabilities of the 2DEG channel give rise to an impressive performance improvement.The proposed 2DEG photodetector exhibits a broad frequency range from 22 to 519 GHz,an ultralow noise equivalent power of 3.0×10^(−14)W Hz^(−1/2)at 166 GHz,and a short response time of 6.7μs.This work provides an effective route for the development of high-performance RT THz detection strategies,paving the way for enhanced THz technology applications.
基金the National Basic Research Program of China(2012CB933301)the National Natural Science Foundation of China(21475064)+4 种基金the Natural Science Foundation of Jiangsu Province of China(BM2012010)the Natural Science Fund for Colleges and Universities in Jiangsu Province(13KJB140009)the Sci-tech Support Plan of Jiangsu Province(BE2014719)the Research Innovation Program for College Graduates of Jiangsu Province(SJZZ15_0107)the Priority Academic Program Development of Jiangsu Higher Education Institutions(YX03001)
文摘Mercury ion(Hg^(2+)),known as one of the highly toxic and soluble heavy metal ions,is causing serious environmental pollution and irreversible damage to the health.It is urgent to develop some rapid and ultrasensitive methods for detecting trace mercury ions in the environment especially drink water.Surface-enhanced Raman scattering(SERS)is considered as a novel and powerful optical analysis technique since it has the significant advantages of ultra-sensitivity and high specificity.In recent years,the SERS technique and its application in the detection of Hg^(2+)have become more prevalent and compelling.This review provides an overall survey of the development of SERS-based Hg^(2+)detections and presents a summary relating to the basic principles,detection strategies,recent advances and current challenges of SERS for Hg^(2+)detections.
