From March 29 to April 7, Sir Arthur Alexander Foulkes, deputy Governor General of the Bahamas and director of Bahamas Information Services, visited Beijing, Xi’an and Shanghai with his wife and assistant at the invi...From March 29 to April 7, Sir Arthur Alexander Foulkes, deputy Governor General of the Bahamas and director of Bahamas Information Services, visited Beijing, Xi’an and Shanghai with his wife and assistant at the invitation of the CPAFFC. Vice Chairperson of the Standing Committee of the National People’s Congress Uyunqimg met with him.展开更多
A quantitative structure-activity relationship （QSAR） model on depuration rate constants （ka） of polychlorinated biphenyls （PCBs） in freshwater mussel Elliptio complanata was successfully constructed using elect...A quantitative structure-activity relationship （QSAR） model on depuration rate constants （ka） of polychlorinated biphenyls （PCBs） in freshwater mussel Elliptio complanata was successfully constructed using electrotopological state indices （ESI） and partial least squares （PLS） regression. The cross validated 2 Qcum and the correlation coefficient R for the model were determined to be 0.845 and 0.954, respectively. The satisfactory Q2cum and R values indicated significantly high robustness and good predictive ability for the model. The model was tested and found acceptable for the prediction of logkd （the logarithm of the deputation rate constants） by validation set. According to the model, an increase in the values of Saasc, S5＇, S4, S5 and S4＇, led to increased logkd, and a decrease in the values of Na, S2, and S6 also resulted in increased logkd. Among these descriptors, Ncl, S aasC, S5＇,, S4 and S5 made significant contributions to the value of logkd. These significant descriptors showed that the depuration of PCBs in Elliptio complanata may be mainly attributed to an equilibrium partitioning process among compartments with different lipid contents, while the reactivity of PCBs with enzymes or other molecules may play a subordinate role.展开更多
文摘From March 29 to April 7, Sir Arthur Alexander Foulkes, deputy Governor General of the Bahamas and director of Bahamas Information Services, visited Beijing, Xi’an and Shanghai with his wife and assistant at the invitation of the CPAFFC. Vice Chairperson of the Standing Committee of the National People’s Congress Uyunqimg met with him.
基金supported by the Major State Basic Research Development Program(No. 2009CB421605)the National Natural Science Foundation of China(No.40871218)+1 种基金the Special Fund of State Key Laboratory(No.08ESPCT-Y)the Program for New Century Excellent Talents in Universities
文摘A quantitative structure-activity relationship （QSAR） model on depuration rate constants （ka） of polychlorinated biphenyls （PCBs） in freshwater mussel Elliptio complanata was successfully constructed using electrotopological state indices （ESI） and partial least squares （PLS） regression. The cross validated 2 Qcum and the correlation coefficient R for the model were determined to be 0.845 and 0.954, respectively. The satisfactory Q2cum and R values indicated significantly high robustness and good predictive ability for the model. The model was tested and found acceptable for the prediction of logkd （the logarithm of the deputation rate constants） by validation set. According to the model, an increase in the values of Saasc, S5＇, S4, S5 and S4＇, led to increased logkd, and a decrease in the values of Na, S2, and S6 also resulted in increased logkd. Among these descriptors, Ncl, S aasC, S5＇,, S4 and S5 made significant contributions to the value of logkd. These significant descriptors showed that the depuration of PCBs in Elliptio complanata may be mainly attributed to an equilibrium partitioning process among compartments with different lipid contents, while the reactivity of PCBs with enzymes or other molecules may play a subordinate role.
