Demo</span><span style="font-family:Verdana;">ns-Meigs syndrome combines a benign tumor of the ovary with thorac</span><span style="font-family:Verdana;">ic and abdominal<...Demo</span><span style="font-family:Verdana;">ns-Meigs syndrome combines a benign tumor of the ovary with thorac</span><span style="font-family:Verdana;">ic and abdominal</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">effusion, it is a rare disease whose pathophysiological mechanism is not yet well understood.</span><span style="font-family:""> </span><span style="font-family:Verdana;">This rare syndrome often gives rise to fear of ovarian neoplasia due to the existence of ascites and the significant elevation of CA 125. In this observation, we report the case of Demons-Meigs syndrome diagnosed in a 36-year-old young woman who presented with pleural and peritoneal effusion syndrome with an</span><span style="font-family:""> </span><span style="font-family:Verdana;">ovarian mass and a CA 125 level = 406.6</span><span style="font-family:""> </span><span style="font-family:Verdana;">IU/ml.</span><span style="font-family:""> </span><span style="font-family:Verdana;">Laparotomy performed revealed very abundant ascites, the uterus and tubes were healthy, no</span><span style="font-family:""> </span><span style="font-family:Verdana;">suspicious peritoneal lesions, the left ovary is healthy, a right ovarian mass of 300 </span><span style="font-family:""><span style="font-family:Verdana;">×</span><span style="font-family:Verdana;"> 150</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">mm.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">A right annexectomy was performed. The operative suites were simple with drying of the</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">effusions. Th</span><span style="font-family:Verdana;">e control CA 125 returned to normal after 6 months of follow-up. A path</span><span style="font-family:Verdana;">ological anatomy result is a fibrothecoma. Demons-Meigs syndrome has a good prognosis;treatment is based on removal of the ovarian tumor.展开更多
Introduction: Demons-Meigs syndrome combines a benign tumor of the ovary with ascites and pleural effusion. It is a rare disease and the pathophysiological mechanism is not yet well understood. The aim of our study is...Introduction: Demons-Meigs syndrome combines a benign tumor of the ovary with ascites and pleural effusion. It is a rare disease and the pathophysiological mechanism is not yet well understood. The aim of our study is to report a case of Demons-Meigs syndrome, to determine its different characteristics and to make clinicians aware of the malignant predictive value of CA 125 in front of an ovarian tumor. Observation: The patient was 42 years old and had no previous history. She presented with intense abdominal pain of sudden onset, prompting a medical consultation. On clinical examination, the abdomen was distended with signs of peritoneal effusion and right pleural effusion. Ultrasound revealed a well-circumscribed, ovarian mass with an internal fluid component and hypervascularization on Doppler. The CA 125 level was elevated (293.9 U/ml). Exploratory laparotomy revealed two bilateral, firm, solid ovarian tumors without vegetation or peritoneal lesions. Macroscopically, one of the tumors was well circumscribed, lobulated with a smooth outer surface. It measured 20 × 17 × 8 cm and weighed 1400 g. The other tumor measured 19 × 11 × 5 cm, weighed 1090 g and had the same characteristics as the other tumor. Histologically, both tumors were a proliferation of fibroblastic spindle cells organized in short intersecting or storiform bundles, without cyto-nuclear atypia or excess mitoses. The diagnosis retained was bilateral ovarian fibroma in the context of a Demons-Meigs syndrome. Conclusion: Demons-Meigs syndrome is a rare entity. The concomitant elevation of the CA 125 level is not always an indicator of ovarian cancer. The curative treatment is surgical based on tumor removal ensuring the disappearance of peritoneal and pleural effusions.展开更多
文摘Demo</span><span style="font-family:Verdana;">ns-Meigs syndrome combines a benign tumor of the ovary with thorac</span><span style="font-family:Verdana;">ic and abdominal</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">effusion, it is a rare disease whose pathophysiological mechanism is not yet well understood.</span><span style="font-family:""> </span><span style="font-family:Verdana;">This rare syndrome often gives rise to fear of ovarian neoplasia due to the existence of ascites and the significant elevation of CA 125. In this observation, we report the case of Demons-Meigs syndrome diagnosed in a 36-year-old young woman who presented with pleural and peritoneal effusion syndrome with an</span><span style="font-family:""> </span><span style="font-family:Verdana;">ovarian mass and a CA 125 level = 406.6</span><span style="font-family:""> </span><span style="font-family:Verdana;">IU/ml.</span><span style="font-family:""> </span><span style="font-family:Verdana;">Laparotomy performed revealed very abundant ascites, the uterus and tubes were healthy, no</span><span style="font-family:""> </span><span style="font-family:Verdana;">suspicious peritoneal lesions, the left ovary is healthy, a right ovarian mass of 300 </span><span style="font-family:""><span style="font-family:Verdana;">×</span><span style="font-family:Verdana;"> 150</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">mm.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">A right annexectomy was performed. The operative suites were simple with drying of the</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">effusions. Th</span><span style="font-family:Verdana;">e control CA 125 returned to normal after 6 months of follow-up. A path</span><span style="font-family:Verdana;">ological anatomy result is a fibrothecoma. Demons-Meigs syndrome has a good prognosis;treatment is based on removal of the ovarian tumor.
文摘Introduction: Demons-Meigs syndrome combines a benign tumor of the ovary with ascites and pleural effusion. It is a rare disease and the pathophysiological mechanism is not yet well understood. The aim of our study is to report a case of Demons-Meigs syndrome, to determine its different characteristics and to make clinicians aware of the malignant predictive value of CA 125 in front of an ovarian tumor. Observation: The patient was 42 years old and had no previous history. She presented with intense abdominal pain of sudden onset, prompting a medical consultation. On clinical examination, the abdomen was distended with signs of peritoneal effusion and right pleural effusion. Ultrasound revealed a well-circumscribed, ovarian mass with an internal fluid component and hypervascularization on Doppler. The CA 125 level was elevated (293.9 U/ml). Exploratory laparotomy revealed two bilateral, firm, solid ovarian tumors without vegetation or peritoneal lesions. Macroscopically, one of the tumors was well circumscribed, lobulated with a smooth outer surface. It measured 20 × 17 × 8 cm and weighed 1400 g. The other tumor measured 19 × 11 × 5 cm, weighed 1090 g and had the same characteristics as the other tumor. Histologically, both tumors were a proliferation of fibroblastic spindle cells organized in short intersecting or storiform bundles, without cyto-nuclear atypia or excess mitoses. The diagnosis retained was bilateral ovarian fibroma in the context of a Demons-Meigs syndrome. Conclusion: Demons-Meigs syndrome is a rare entity. The concomitant elevation of the CA 125 level is not always an indicator of ovarian cancer. The curative treatment is surgical based on tumor removal ensuring the disappearance of peritoneal and pleural effusions.
