Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyro...Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyroidism.This study aims to attribute the trends in AF/AFL-related mortalities over the past two decades 1999-2020 concerning race and sex and disparity among them.To the best of our knowledge,this is the first study that estimates the trends and mortality due to AF/AFL from 1999-2020 in older adults in the United States.In this 21-year analysis of mortality data,we found a constant increase in mortality rates due to AF/AFL in older adults.From 1999 to 2020,the overall mortality in older adults aged 65 and above,regardless of sex and race,is found to be almost doubled i.e.about a 50.2%increase in the number of deaths due to AF/AFL.Furthermore,other confounding risk factors such has obesity,prior myocardial infarction,inflammation,hypertension,birth weight,diabetes mellitus,hyperthyroidism,hormone replacement therapy in menopausal women increases the risk in the occurrence or recurrent occurrence of AF.展开更多
Cropland abandonment has been a widespread phenomenon in mountainous areas due to the increasing number of natural disasters and the massive migration of rural labor in the process of rapid urbanization.Land transfer ...Cropland abandonment has been a widespread phenomenon in mountainous areas due to the increasing number of natural disasters and the massive migration of rural labor in the process of rapid urbanization.Land transfer is a crucial prerequisite for ensuring food security and fostering rural revitalization.How to promote land transfer in mountainous areas remains a challenging but important task.Nevertheless,there is a dearth of research examining land transfers among farm households that specifically address mountainous regions,and the influence of grassroots governance and geographic location has not been thoroughly elucidated within this particular context.Based on 895household samples collected in Dabie Mountainous Area in China,this study employs binary and ordinal logistic regression models to provide a more comprehensive analysis on land transfers among rural households and the determinants,including the decision to transfer land,the existence of land transfer rents,the channel of land transfer,the duration of the transfer,the pre-transfer cultivation situation,and the level of satisfaction with the land transfer rent.The findings reveal that grassroots governance,geographic location,livelihood capital,and demographic factors significantly influence land transfers among rural households.Specifically,villagers'public participation positively affects land transfer participation(β=0.235,p<0.05),while the operation of village rules and regulations negatively impacts it(β=-0.296,p<0.05).Village cadre satisfaction positively influences both land transfer rent(β=0.274,p<0.05)and rent satisfaction(β=0.303,p<0.05).Improved civil relations in the village correlate with lower land transfer rent(β=-0.511,p<0.05),while a better social atmosphere is associated with higher satisfaction with transfer rent(β=0.575,p<0.01).Households at higher elevations tend to prefer government-mediated land transfers with longer durations.The distances to the township and county centers have contrasting effects on land transfer rent,but their impacts on participation in land transfer,choice of transfer channel,and duration are consistent.The study also found that different types of livelihood capital,as well as the demographic characteristics of households,significantly affect various aspects of land transfer.These empirical findings can inform policymaking to promote more efficient land transfers in mountainous region.展开更多
BACKGROUND Ovarian carcinoma has the highest mortality rate among all gynecological cancers.Several reproductive and hormonal risk factors,including early menarche,late menopause,limited use of oral contraceptives,and...BACKGROUND Ovarian carcinoma has the highest mortality rate among all gynecological cancers.Several reproductive and hormonal risk factors,including early menarche,late menopause,limited use of oral contraceptives,and a low pregnancy rate,have been identified as contributors to the increased susceptibility to ovarian cancer.Advancements in cancer therapy over the past century,including the emergence of precision oncology,underscore the importance of early detection and tailored interventions,factors particularly critical in ovarian cancer,where late-stage diagnosis remains a persistent barrier to survival.This challenge is compounded by the lack of a universally endorsed screening program,resulting in late-stage identification and widespread metastasis.AIM To evaluate demographic differences in ovarian cancer-related mortality from 1999 to 2020 among adult females aged≥25 years within the United States.METHODS Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was used to collect de-identified death certificate data for malignant neoplasm of the ovaries related deaths in female adults aged 25 years and older from the year 1999 to 2020.Crude mortality rates and age-adjusted mortality rates(AAMRs)per 100000 people were calculated.Join point regression program was used to assess annual percent changes in mortality trends,with statistical significance set at P value<0.05.RESULTS Between 1999 and 2020,337619 deaths due to ovarian cancer occurred among United States females aged 25 to>85.The AAMR decreased from 14.62 in 1999 to 10.15 in 2020,with significant declines across various demographics.The AAMRs were highest among non-Hispanic White women,i.e.,13.53.Based on region,they were the highest in the Northeast(13.06)and Midwest(12.94).The steepest decline was observed in metropolitan areas as compared to nonmetropolitan ones.The study highlights significant progress in reducing ovarian cancer mortality across age,race/ethnicity,and geographic regions during this period.CONCLUSION The mortality trends for ovarian carcinoma patients showed an overall decrease,with the highest mortality rates observed among older individuals(65 to>85 years)and non-Hispanic Whites.These disparities underscore the need for equitable healthcare access and targeted policy interventions.展开更多
Hu sheep is an indigenous breed from the Taihu Lake Plain in China,known for its high fertility.Although Hu sheep belong to the Mongolian group,their demographic history and genetic architecture remain inconclusive.He...Hu sheep is an indigenous breed from the Taihu Lake Plain in China,known for its high fertility.Although Hu sheep belong to the Mongolian group,their demographic history and genetic architecture remain inconclusive.Here,we analyze 697 sheep genomes from representatives of Mongolian sheep breeds.Our study suggests that the ancestral Hu sheep first separated from the Mongolian group approximately 3000 years ago.As Hu sheep migrated from the north and flourished in the Taihu Lake Plain around 1000 years ago,they developed a unique genetic foundation and phenotypic characteristics,which are evident in the genomic footprints of selective sweeps and structural variation landscape.Genes associated with reproductive traits(BMPR1B and TDRD10)and horn phenotype(RXFP2)exhibit notable selective sweeps in the genome of Hu sheep.A genome-wide association analysis reveals that structural variations at LOC101110773,MAST2,and ZNF385B may significantly impact polledness,teat number,and early growth in Hu sheep,respectively.Our study offers insights into the evolutionary history of Hu sheep and may serve as a valuable genetic resource to enhance the understanding of complex traits in Hu sheep.展开更多
This study examines how demographic factors shape engagement with virtual cultural communities and awareness of emerging economic models.Using survey data from 202 participants,descriptive statistics,independent sampl...This study examines how demographic factors shape engagement with virtual cultural communities and awareness of emerging economic models.Using survey data from 202 participants,descriptive statistics,independent samples t-tests,and One-way Analysis of Variance(ANOVA)with Least Significant Difference(LSD)post-hoc analyses revealed significant influences of age,education,and occupation.No significant gender differences were found.Individuals aged 26-45 demonstrated higher virtual community participation(F=3.439,p=0.01)and emerging model awareness(F=2.834,p=0.026)than younger cohorts(18-25 years and below).Respondents with postgraduate education exhibited superior understanding of emerging economic models(F=3.296,p=0.022)and their nexus with cultural values(F=6.196,p<0.001)compared to those with lower educational attainment.Significant occupational variations existed in virtual participation(F=4.001,p=0.008)and economic model awareness(F=5.611,p=0.001),with enterprise employees and civil servants scoring higher than students and freelancers.These findings underscore the critical roles of life stage,educational investment,and professional context in shaping digital cultural behaviors and economic cognition,offering valuable insights for platform design,educational strategies,and policy development in the digital cultural economy.展开更多
Preserving genetic diversity is crucial for the long-term survival of wild plant species,yet many remain at risk of genetic erosion due to small population sizes and habitat fragmentation.Here,we present a comparative...Preserving genetic diversity is crucial for the long-term survival of wild plant species,yet many remain at risk of genetic erosion due to small population sizes and habitat fragmentation.Here,we present a comparative genomic study of the critically endangered Oreocharis esquirolii(Gesneriaceae)and its widespread congener O.maximowiczii.We assembled and annotated chromosome-level reference genomes for both species and generated whole-genome resequencing data from 28 O.esquirolii and 79 O.maximowiczii individuals.Our analyses reveal substantially lower genetic diversity and higher inbreeding in O.esquirolii,despite its overall reduced mutational burden.Notably,O.esquirolii exhibits an elevated proportion of strongly deleterious mutations relative to O.maximowiczii,suggesting that limited opportunities for purging have allowed these variants to accumulate.These contrasting genomic profileslikely reflectdivergent demographic histories,with O.esquirolii having experienced severe bottlenecks and protracted population decline.Collectively,our findingshighlight the critically endangered status of O.esquirolii,characterized by diminished genetic diversity,pronounced inbreeding,and reduced ability to eliminate deleterious alleles.This study provides valuable genomic resources for the Gesneriaceae family and underscores the urgent need for targeted conservation measures,including habitat protection and ex situ preservation efforts,to mitigate the extinction risk facing O.esquirolii and potentially other threatened congeners.展开更多
Climate change is expected to alter the popu-lation dynamics of pioneer tree species and their planned use in sustainable forest management,but we have a lim-ited understanding of how their demographic rates change in...Climate change is expected to alter the popu-lation dynamics of pioneer tree species and their planned use in sustainable forest management,but we have a lim-ited understanding of how their demographic rates change in response to climate changes during ecological restora-tion.Based on 12 years of demographic data for a pioneer tree species(Pinus massoniana)censused in three plots that correspond to three stages of ecological restoration in south-eastern China.We built integral projection models(IPMs)to assess vital rates(survival,growth,reproduction)and population growth in each plot,then evaluated demographic changes to simulated changes in seasonal mean temperature and precipitation in the current and previous census period.The plot representing the medium restoration stage had the highest population growth rate(λ=0.983).Mean population survival probability increased with ecological restoration,and reproduction probability was significantly suppressed at the high restoration stage.Survival is always the most important vital rate forλ,and climate affectsλprimarily via survival at each restoration stage.The current spring tem-perature was the most critical climate variable forλin the low and medium restoration stages,and previous summer temperature was most critical in the high restoration stage.Simulated warming leads to a decrease in the stochastic population growth rate(λ_(s))of P.massoniana in every stage.These findings suggest that during ecological restoration,P.massoniana responds to habitat change via modified demo-graphic performance,thus altering its response to climate change.Despite diverse responses to climate change,the persistence of P.massoniana populations is facing a wide-spread threat of warming states at each restoration stages.展开更多
With increasing population and changing demographics,food consumption has experienced a significant transition in quantity and quality.However,a dearth of knowledge remains regarding its environmental impacts and how ...With increasing population and changing demographics,food consumption has experienced a significant transition in quantity and quality.However,a dearth of knowledge remains regarding its environmental impacts and how it responds to demographic dynamics,particularly in emerging economies like China.Using the two-stage Quadratic Almost Demand System(QUAIDS)model,this study empirically examines the impact of demographic dynamics on food consumption and its environmental outcomes based on the provincial data from 2000 to 2020 in China.Under various scenarios,according to changes in demographics,we extend our analysis to project the long-term trend of food consumption and its environmental impacts,including greenhouse gas(GHG)emissions,water footprint(WF),and land appropriation(LA).The results reveal that an increase in the proportion of senior people significantly decreases the consumption of grain and livestock meat and increases the consumption of poultry,egg,and aquatic products,particularly for urban residents.Moreover,an increase in the proportion of males in the population leads to higher consumption of poultry and aquatic products.Correspondingly,in the current scenario of an increased aging population and sex ratio,it is anticipated that GHG emissions,WF,and LA are likely to decrease by 1.37,2.52,and 3.56%,respectively.More importantly,in the scenario adhering to the standards of nutritional intake according to the Dietary Guidelines for Chinese Residents in 2022,GHG emissions,WF,and LA in urban areas would increase by 12.78,20.94,and 18.32%,respectively.Our findings suggest that changing demographics should be considered when designing policies to mitigate the diet-environment-health trilemma and achieve sustainable food consumption.展开更多
Objective:To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in China.Methods: Elderly individuals from seven regions in China...Objective:To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in China.Methods: Elderly individuals from seven regions in China were selected as samples in this study using a multistage cluster random sampling method.The basic information questionnaire and Constitution in Chinese Medicine Questionnaire(Elderly Edition)were used.Descriptive statistical analysis,chi-squared tests,and binary logistic regression analysis were used.Results: The single balanced constitution(BC)accounted for 23.9%.The results of the major TCM constitution types showed that BC(43.2%)accounted for the largest proportion and unbalanced constitutions ranged from 0.9%to 15.7%.East China region(odds ratio[OR]=2.097;95%confidence interval[CI],1.912 to 2.301),married status(OR=1.341;95%CI,1.235 to 1.457),and managers(OR=1.254;95%CI,1.044 to 1.505)were significantly associated with BC.Age>70 years was associated with qi-deficiency constitution and blood stasis constitution(BSC).Female sex was significantly associated with yang-deficiency constitution(OR=1.646;95%CI,1.52 to 1.782).Southwest region was significantly associated with phlegm-dampness constitution(OR=1.809;95%CI,1.569 to 2.086).North China region was significantly associated with inherited special constitution(OR=2.521;95%CI,1.569 to 4.05).South China region(OR=2.741;95%CI,1.997 to 1.3.763),Central China region(OR=8.889;95%CI,6.676 to 11.835),senior middle school education(OR=2.442;95%CI,1.932 to 3.088),and managers(OR=1.804;95%CI,1.21 to 2.69)were significantly associated with BSC.Conclusions: This study defined the distribution characteristics and demographic factors of TCM constitution in the elderly population.Adjusting and improving unbalanced constitutions,which are correlated with diseases,can help promote healthy aging through the scientific management of these demographic factors.展开更多
The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse origin.This study was a large-scale genome-wide analysis of the landscape of the complex molecula...The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse origin.This study was a large-scale genome-wide analysis of the landscape of the complex molecular architecture,genetic variability,and detailed structure among 49 populations.These populations represent a significant sample of the world's chicken breeds from Europe(Russia,Czech Republic,France,Spain,UK,etc.),Asia(China),North America(USA),and Oceania(Australia).Based on the results of breed genotyping using the Illumina 60K single nucleotide polymorphism(SNP)chip,a bioinformatic analysis was carried out.This included the calculation of heterozygosity/homozygosity statistics,inbreeding coefficients,and effective population size.It also included assessment of linkage disequilibrium and construction of phylogenetic trees.Using multidimensional scaling,principal component analysis,and ADMIXTURE-assisted global ancestry analysis,we explored the genetic structure of populations and subpopulations in each breed.An overall 49-population phylogeny analysis was also performed,and a refined evolutionary model of chicken breed formation was proposed,which included egg,meat,dual-purpose types,and ambiguous breeds.Such a large-scale survey of genetic resources in poultry farming using modern genomic methods is of great interest both from the viewpoint of a general understanding of the genetics of the domestic chicken and for the further development of genomic technologies and approaches in poultry breeding.In general,whole genome SNP genotyping of promising chicken breeds from the worldwide gene pool will promote the further development of modern genomic science as applied to poultry.展开更多
“Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy makers.The rising conflict between human beings and wild elephants is common in Bu...“Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy makers.The rising conflict between human beings and wild elephants is common in Buxa Tiger Reserve(BTR)and its adjoining area in West Bengal State,India,making the area volatile.People’s attitudes towards elephant conservation activity are very crucial to get rid of HEC,because people’s proximity with wild elephants’habitat can trigger the occurrence of HEC.The aim of this study is to conduct an in-depth investigation about the association of people’s attitudes towards HEC with their locational,demographic,and socio-economic characteristics in BTR and its adjoining area by using Pearson’s bivariate chi-square test and binary logistic regression analysis.BTR is one of the constituent parts of Eastern Doors Elephant Reserve(EDER).We interviewed 500 respondents to understand their perceptions to HEC and investigated their locational,demographic,and socio-economic characteristics including location of village,gender,age,ethnicity,religion,caste,poverty level,education level,primary occupation,secondary occupation,household type,and source of firewood.The results indicate that respondents who are living in enclave forest villages(EFVs),peripheral forest villages(PFVs),corridor village(CVs),or forest and corridor villages(FCVs),mainly males,at the age of 18–48 years old,engaged with agriculture occupation,and living in kancha and mixed houses,have more likelihood to witness HEC.Besides,respondents who are illiterate or at primary education level are more likely to regard elephant as a main problematic animal around their villages and refuse to participate in elephant conservation activity.For the sake of a sustainable environment for both human beings and wildlife,people’s attitudes towards elephants must be friendly in a more prudent way,so that the two communities can live in harmony.展开更多
BACKGROUND The Limb Lengthening and Reconstruction Society(LLRS)is a premier orthopedic specialty organization that promotes limb reconstruction for all ages.LLRS membership characteristics,however,are poorly reported...BACKGROUND The Limb Lengthening and Reconstruction Society(LLRS)is a premier orthopedic specialty organization that promotes limb reconstruction for all ages.LLRS membership characteristics,however,are poorly reported.This study delineates orthopedic surgeon LLRS members’demographic traits,academic achievement,leadership attainment,and geographical distribution across the United States.AIM To inform aspiring orthopedic professionals,as well as to promote growth and diversity in both the LLRS organization and overarching field.METHODS This cross-sectional study examined United States LLRS members’academic,leadership,demographic,and geographical attributes.After reviewing the 2023 LLRS member directory,Google search results were matched to the listings and appended to the compiled data.Sex and ethnicity were evaluated visually utilizing retrieved images.The Hirsch index(H-index)of academic activity,residency and fellowship training,other graduate degrees,leadership positions,practice type(academic or non-academic),and spoken languages were categorized.LLRS members per state and capita determined geographic distribution.The Mann Whitney U test was applied to compare H-index between males and females,as well as to assess member differences pertaining to affiliation with academic vs non-academic practice facilities.RESULTS The study included 101 orthopedic surgeons,78(77.23%)Caucasian and 23(22.77%)non-Caucasian,79(78.22%)male and 22(21.78%)female.Surgeons with DO degrees comprised only 3.96%(4)of the cohort,while the vast majority held MDs[96.04%(97)].Mean H-index was 10.55,with male surgeons having a significantly higher score(P=0.002).Most orthopedic surgeons(88.12%,)practiced in academic centers.Of those professionals who occupied leadership positions,14%were women,while 86%were men.Additionally,19(37.25%)United States regions and the District of Columbia lacked an LLRS-member orthopedic surgeon.Total per capita rate across the United States was 0.30 LLRS orthopedic surgeons per 1 million people.CONCLUSION Over 21%of LLRS members are women,surpassing prior benchmarks noted in orthopedic faculty reporting.LLRS members’high research productivity scores imply field dedication that can refine expertise in the limb lengthening and reconstruction space.Gender disparities in leadership remain,however,necessitating greater equity efforts.A low rate of LLRS representation per capita must be addressed geographically as well,to affect improvements in regional care access.This study can serve to support aspiring orthopedic professionals,inform diversity,leadership,and field advancement strategies,and maintain the continued goal of enhanced patient care worldwide.展开更多
Background: In Sub-Saharan Africa, pre-eclampsia remains a major health problem contributing to high rates of maternal mortality. Despite this condition having adverse effects on maternal and child health, its prevale...Background: In Sub-Saharan Africa, pre-eclampsia remains a major health problem contributing to high rates of maternal mortality. Despite this condition having adverse effects on maternal and child health, its prevalence and associated risk factors are still significant, especially in developing countries including Ghana. This study aimed to assess the prevalence and demographic distributions associated with pre-eclampsia among pregnant women at the Ho Teaching Hospital. Methods: A facility-based retrospective study was conducted by reviewing available data or hospital records of pregnant mothers admitted to the labor and maternity wards from January 2018 to December 2020. All pregnant women who were diagnosed with pre-eclampsia within this period were included in the study. The data were collected using a structured checklist. Results: 5609 data on pregnant women from 2018 to 2020 were recorded. Out of the 5609 data recorded, 314 pre-eclampsia cases were recorded giving an overall prevalence of 5.6%. The yearly prevalence for 2018, 2019, and 2020 were 4.6%, 5.6%, and 6.6%, respectively. The most recorded pre-eclampsia cases were seen among women within the age group of 18 - 24 years. The data showed that 112 (35.7%) of the pregnant women who had pre-eclampsia were nulliparous. Pre-eclampsia-associated maternal and fetal complications were;preterm delivery 221 (70.4%), intrauterine fetal death 62 (19.7%), eclampsia 9 (2.9%), HELLP syndrome 5 (1.6%) and maternal death 17 (5.4%). Associated factors of pre-eclampsia were parity, level of education, and occupation (p ≤ 0.05). Conclusion: The findings of this study showed a rising trend in the incidence of pre-eclampsia over the years at the Ho Teaching Hospital. Parity, level of education, and occupation were found to be associated with developing pre-eclampsia.展开更多
Globally,population dynamics are shifting towards increased life expectancy,and many countries,including Greece,face significant demographic challenges.Greece is particularly impacted by one of the lowest birth rates ...Globally,population dynamics are shifting towards increased life expectancy,and many countries,including Greece,face significant demographic challenges.Greece is particularly impacted by one of the lowest birth rates in the world and a rapidly aging population.This demographic shift places unprecedented pressure on the nation’s pension systems and economic stability,as more people retire than enter the workforce.This study aims to explore the historical factors contributing to Greece’s demographic situation,analyze the consequences of current trends,and propose strategic solutions.The research utilizes a literature review approach and the case study of Greece to understand the depth and breadth of the demographic crisis.Key areas of focus include the declining birth rate,the economic implications of an aging population,and the potential of migration and policy reform to rejuvenate demographic dynamics.The study evaluates various policy interventions from other countries to propose a tailored,multi-faceted strategy for Greece.These strategies emphasize economic incentives for young families,improved childcare and parental support,healthcare investment,and inclusive migration policies to enhance workforce numbers.This comprehensive approach seeks to provide actionable insights that can help Greece mitigate the effects of demographic decline and foster a more sustainable future,aligning policy interventions with socio-economic and cultural realities.展开更多
Objective and Impact Statement:The multi-quantification of the distinct individualized maxillofacial traits,that is,quantifying multiple indices,is vital for diagnosis,decision-making,and prognosis of the maxillofacia...Objective and Impact Statement:The multi-quantification of the distinct individualized maxillofacial traits,that is,quantifying multiple indices,is vital for diagnosis,decision-making,and prognosis of the maxillofacial surgery.Introduction:While the discrete and demographically disproportionate distributions of the multiple indices restrict the generalization ability of artificial intelligence(AI)-based automatic analysis,this study presents a demographic-parity strategy for AI-based multi-quantification.Methods:In the aesthetic-concerning maxillary alveolar basal bone,which requires quantifying a total of 9 indices from length and width dimensional,this study collected a total of 4,000 cone-beam computed tomography(CBCT)sagittal images,and developed a deep learning model composed of a backbone and multiple regression heads with fully shared parameters to intelligently predict these quantitative metrics.Through auditing of the primary generalization result,the sensitive attribute was identified and the dataset was subdivided to train new submodels.Then,submodels trained from respective subsets were ensembled for final generalization.Results:The primary generalization result showed that the AI model underperformed in quantifying major basal bone indices.The sex factor was proved to be the sensitive attribute.The final model was ensembled by the male and female submodels,which yielded equal performance between genders,low error,high consistency,satisfying correlation coefficient,and highly focused attention.The ensemble model exhibited high similarity to clinicians with minor processing time.Conclusion:This work validates that the demographic parity strategy enables the AI algorithm with greater model generalization ability,even for the highly variable traits,which benefits for the appearance-concerning maxillofacial surgery.展开更多
A great discovery made by H. von Foerster, P. M. Mora and L. W. Amiot was published in a 1960 issue of “Science”. The authors showed that existing data for calculating the Earth’s population in the new era (from 1 ...A great discovery made by H. von Foerster, P. M. Mora and L. W. Amiot was published in a 1960 issue of “Science”. The authors showed that existing data for calculating the Earth’s population in the new era (from 1 to 1958) could be described with incredibly high proximity by a hyperbolic function with the point of singularity on 13 November 2026. Thus, empirical regularity of the rise of the human population was established, which was marked by explosive demographic growth in the 20<sup>th</sup> century when during only one century it almost quadrupled: from 1.656 billion in 1900 to 6.144 billion in 2000. Nowadays, the world population has already overcome 7.8 billion people. Immediately after 1960, an active search for phenomenological models began to explain the mechanism of the hyperbolic population growth and the following demographic transition designed to stabilize its population. A significant role in explaining the mechanism of the hyperbolic growth of the world population was played by S. Kuznets (1960) and E. Boserup (1965), who found out that the rates of technological progress historically increased in proportion to the Earth’s population. It meant that the growth of the population led to raising the level of life-supporting technologies, and the latter in its turn enlarged the carrying capacity of the Earth, making it possible for the world population to expand. Proceeding from the information imperative, we have developed the model of the demographic dynamics for the 21<sup>st</sup> century for the first time. The model shows that with the development and spread of Intelligent Machines (IM), the number of the world population reaching a certain maximum will then irreversibly decline. Human depopulation will largely touch upon the most developed countries, where IM is used intensively nowadays. Until a certain moment in time, this depopulation in developed countries will be compensated by the explosive growth of the population in African countries located south of the Sahara. Calculations in our model reveal that the peak of the human population of 8.52 billion people will be reached in 2050, then it will irreversibly go down to 7.9 billion people by 2100, if developed countries do not take timely effective measures to overcome the process of information depopulation.展开更多
The decline in the birth rate,which has been uninterrupted in Italy since the mid-1960s,has had a significant impact on many aspects of society.As far as the educational system is concerned,this phenomenon has acted l...The decline in the birth rate,which has been uninterrupted in Italy since the mid-1960s,has had a significant impact on many aspects of society.As far as the educational system is concerned,this phenomenon has acted like a wave,first causing a decline in the population of the first school age groups,then in the other groups,until recently affecting the 19-25 age group,which includes the majority of university students.As a result,the majority of Italian universities have seen a decline over time in both enrollments(matriculations)and student numbers(enrollments),although the situation varies from one area to another.In the Mezzogiorno,this trend is even more pronounced,since an increasing number of resident students tend to favor universities in the Centre-North,creating a South-Centre-North movement,which could be compared to a particular form of cultural tourism,without a similar flow in the opposite direction.Finally,the study highlights the probable consequences of the recent demographic depopulation on the future trend of university enrollment of residents aged 19-25 in the Calabria region,using the most recent demographic projections of Istat and constructing two evolutionary scenarios.In the first scenario,we have assumed that in the near future university enrollment rates remain constant throughout the period considered;in the second scenario,these rates instead experience a gradual and continuous increase.These results could be useful if further forecasts of university enrollments were to be made at the level of individual Calabrian universities.展开更多
Given the great strides that China＇s education sector has made in recent decades, it can be expected that the overall workforce quality of exiting China＇s labor market in coming one or two decades will be relatively...Given the great strides that China＇s education sector has made in recent decades, it can be expected that the overall workforce quality of exiting China＇s labor market in coming one or two decades will be relatively low, while the overall quality of workforce newly entering into China＇s labor market will be high. As the new, bettereducated generation takes over, China＇s workforce quality will be vastly improved. This in turn will promote economic growth. We refer to economic growth arising from improved workforce quality as qualitative demographic dividend. Using the computable general equilibrium （CGE） model, this paper investigates the relationship between workforce quality improvements and economic growth. According to the model＇s results, an improvement in workforce quality will raise the economic growth rate by about two percentage points per annum between 2016 and 2020 and by 10 percentage points cumulatively by 2020. In other words, GDP will be 1.1 times the level of baseline GDP by 2020 due to the improved education levels. Given different production functions across sectors, the improvement of workforce quality will affect different sectors in different ways. On the whole, the improvement of workforce quality is more favorable to the development of capital-intensive sectors and sectors with rapid technology progress. According to this paper, considering the improvement of workforce quality, we cannot conclude that China＇s potential economic growth rate has already begun to decline. Despite diminishing conventional quantitative demographic dividends, China ＂s qualitative demographic dividends will keep rising. Qualitative demographic dividends will further push forward China＇s industrial restructuring and the strategic transition of industrial competitiveness from quantitative to qualitative and from an extensive to an intensive pattern of development.展开更多
[Objective] The aim was to analyze the phenomenon of employment diffi- culty and labor shortage, and to reveal the influencing factors of employment difli- culty and labor shortage. [Method] On the basis of the econom...[Objective] The aim was to analyze the phenomenon of employment diffi- culty and labor shortage, and to reveal the influencing factors of employment difli- culty and labor shortage. [Method] On the basis of the economic principle of popu- lation dividend, the use of human resources and natural resource constraints The IS-LM model describes these two states. [Results] The resource constraints have a ＂squeeze＂ effect on the demographic dividend, and employment pressure is shown in terms of the population opportunity window; the labor market segmentation, the ir- rational industrial structure, the backward curriculum and employment concept are the main factors affecting employment and labor shortage. [Conclusion] The way to solve this dilemma must be removed from the division of labor market, the adjust- ment of industrial structure, the setting of university specialty, the change of em- ployment concept of university graduates as well as the improvement of the quality of labor.展开更多
文摘Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyroidism.This study aims to attribute the trends in AF/AFL-related mortalities over the past two decades 1999-2020 concerning race and sex and disparity among them.To the best of our knowledge,this is the first study that estimates the trends and mortality due to AF/AFL from 1999-2020 in older adults in the United States.In this 21-year analysis of mortality data,we found a constant increase in mortality rates due to AF/AFL in older adults.From 1999 to 2020,the overall mortality in older adults aged 65 and above,regardless of sex and race,is found to be almost doubled i.e.about a 50.2%increase in the number of deaths due to AF/AFL.Furthermore,other confounding risk factors such has obesity,prior myocardial infarction,inflammation,hypertension,birth weight,diabetes mellitus,hyperthyroidism,hormone replacement therapy in menopausal women increases the risk in the occurrence or recurrent occurrence of AF.
基金supported by the National Natural Science Foundation of China(Grant Nos.42371315,41901213)the Humanities and Social Sciences General Research Program of the Ministry of Education(Grant No.23YJC790141)。
文摘Cropland abandonment has been a widespread phenomenon in mountainous areas due to the increasing number of natural disasters and the massive migration of rural labor in the process of rapid urbanization.Land transfer is a crucial prerequisite for ensuring food security and fostering rural revitalization.How to promote land transfer in mountainous areas remains a challenging but important task.Nevertheless,there is a dearth of research examining land transfers among farm households that specifically address mountainous regions,and the influence of grassroots governance and geographic location has not been thoroughly elucidated within this particular context.Based on 895household samples collected in Dabie Mountainous Area in China,this study employs binary and ordinal logistic regression models to provide a more comprehensive analysis on land transfers among rural households and the determinants,including the decision to transfer land,the existence of land transfer rents,the channel of land transfer,the duration of the transfer,the pre-transfer cultivation situation,and the level of satisfaction with the land transfer rent.The findings reveal that grassroots governance,geographic location,livelihood capital,and demographic factors significantly influence land transfers among rural households.Specifically,villagers'public participation positively affects land transfer participation(β=0.235,p<0.05),while the operation of village rules and regulations negatively impacts it(β=-0.296,p<0.05).Village cadre satisfaction positively influences both land transfer rent(β=0.274,p<0.05)and rent satisfaction(β=0.303,p<0.05).Improved civil relations in the village correlate with lower land transfer rent(β=-0.511,p<0.05),while a better social atmosphere is associated with higher satisfaction with transfer rent(β=0.575,p<0.01).Households at higher elevations tend to prefer government-mediated land transfers with longer durations.The distances to the township and county centers have contrasting effects on land transfer rent,but their impacts on participation in land transfer,choice of transfer channel,and duration are consistent.The study also found that different types of livelihood capital,as well as the demographic characteristics of households,significantly affect various aspects of land transfer.These empirical findings can inform policymaking to promote more efficient land transfers in mountainous region.
文摘BACKGROUND Ovarian carcinoma has the highest mortality rate among all gynecological cancers.Several reproductive and hormonal risk factors,including early menarche,late menopause,limited use of oral contraceptives,and a low pregnancy rate,have been identified as contributors to the increased susceptibility to ovarian cancer.Advancements in cancer therapy over the past century,including the emergence of precision oncology,underscore the importance of early detection and tailored interventions,factors particularly critical in ovarian cancer,where late-stage diagnosis remains a persistent barrier to survival.This challenge is compounded by the lack of a universally endorsed screening program,resulting in late-stage identification and widespread metastasis.AIM To evaluate demographic differences in ovarian cancer-related mortality from 1999 to 2020 among adult females aged≥25 years within the United States.METHODS Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was used to collect de-identified death certificate data for malignant neoplasm of the ovaries related deaths in female adults aged 25 years and older from the year 1999 to 2020.Crude mortality rates and age-adjusted mortality rates(AAMRs)per 100000 people were calculated.Join point regression program was used to assess annual percent changes in mortality trends,with statistical significance set at P value<0.05.RESULTS Between 1999 and 2020,337619 deaths due to ovarian cancer occurred among United States females aged 25 to>85.The AAMR decreased from 14.62 in 1999 to 10.15 in 2020,with significant declines across various demographics.The AAMRs were highest among non-Hispanic White women,i.e.,13.53.Based on region,they were the highest in the Northeast(13.06)and Midwest(12.94).The steepest decline was observed in metropolitan areas as compared to nonmetropolitan ones.The study highlights significant progress in reducing ovarian cancer mortality across age,race/ethnicity,and geographic regions during this period.CONCLUSION The mortality trends for ovarian carcinoma patients showed an overall decrease,with the highest mortality rates observed among older individuals(65 to>85 years)and non-Hispanic Whites.These disparities underscore the need for equitable healthcare access and targeted policy interventions.
基金supported by grants from the Zhejiang Science and Technology Department Project(2023C04004)Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding(2021C02068-6)+2 种基金Department of Science Technology of Huzhou City(2023GZ33)Zhejiang Team Technology Ambassador Project(Tongxiang)the National Natural Science Foundation of China(32172724).
文摘Hu sheep is an indigenous breed from the Taihu Lake Plain in China,known for its high fertility.Although Hu sheep belong to the Mongolian group,their demographic history and genetic architecture remain inconclusive.Here,we analyze 697 sheep genomes from representatives of Mongolian sheep breeds.Our study suggests that the ancestral Hu sheep first separated from the Mongolian group approximately 3000 years ago.As Hu sheep migrated from the north and flourished in the Taihu Lake Plain around 1000 years ago,they developed a unique genetic foundation and phenotypic characteristics,which are evident in the genomic footprints of selective sweeps and structural variation landscape.Genes associated with reproductive traits(BMPR1B and TDRD10)and horn phenotype(RXFP2)exhibit notable selective sweeps in the genome of Hu sheep.A genome-wide association analysis reveals that structural variations at LOC101110773,MAST2,and ZNF385B may significantly impact polledness,teat number,and early growth in Hu sheep,respectively.Our study offers insights into the evolutionary history of Hu sheep and may serve as a valuable genetic resource to enhance the understanding of complex traits in Hu sheep.
文摘This study examines how demographic factors shape engagement with virtual cultural communities and awareness of emerging economic models.Using survey data from 202 participants,descriptive statistics,independent samples t-tests,and One-way Analysis of Variance(ANOVA)with Least Significant Difference(LSD)post-hoc analyses revealed significant influences of age,education,and occupation.No significant gender differences were found.Individuals aged 26-45 demonstrated higher virtual community participation(F=3.439,p=0.01)and emerging model awareness(F=2.834,p=0.026)than younger cohorts(18-25 years and below).Respondents with postgraduate education exhibited superior understanding of emerging economic models(F=3.296,p=0.022)and their nexus with cultural values(F=6.196,p<0.001)compared to those with lower educational attainment.Significant occupational variations existed in virtual participation(F=4.001,p=0.008)and economic model awareness(F=5.611,p=0.001),with enterprise employees and civil servants scoring higher than students and freelancers.These findings underscore the critical roles of life stage,educational investment,and professional context in shaping digital cultural behaviors and economic cognition,offering valuable insights for platform design,educational strategies,and policy development in the digital cultural economy.
基金supported by National Key R&D Program of China(2024YFF1307400)Guangdong S&T Program(2022B1111230001).
文摘Preserving genetic diversity is crucial for the long-term survival of wild plant species,yet many remain at risk of genetic erosion due to small population sizes and habitat fragmentation.Here,we present a comparative genomic study of the critically endangered Oreocharis esquirolii(Gesneriaceae)and its widespread congener O.maximowiczii.We assembled and annotated chromosome-level reference genomes for both species and generated whole-genome resequencing data from 28 O.esquirolii and 79 O.maximowiczii individuals.Our analyses reveal substantially lower genetic diversity and higher inbreeding in O.esquirolii,despite its overall reduced mutational burden.Notably,O.esquirolii exhibits an elevated proportion of strongly deleterious mutations relative to O.maximowiczii,suggesting that limited opportunities for purging have allowed these variants to accumulate.These contrasting genomic profileslikely reflectdivergent demographic histories,with O.esquirolii having experienced severe bottlenecks and protracted population decline.Collectively,our findingshighlight the critically endangered status of O.esquirolii,characterized by diminished genetic diversity,pronounced inbreeding,and reduced ability to eliminate deleterious alleles.This study provides valuable genomic resources for the Gesneriaceae family and underscores the urgent need for targeted conservation measures,including habitat protection and ex situ preservation efforts,to mitigate the extinction risk facing O.esquirolii and potentially other threatened congeners.
基金supported by the National Natural Science Foundation of China(grant no.31971638)the Public Welfare Project of Fujian Science and Technology Department(grant no.2024R1002001).
文摘Climate change is expected to alter the popu-lation dynamics of pioneer tree species and their planned use in sustainable forest management,but we have a lim-ited understanding of how their demographic rates change in response to climate changes during ecological restora-tion.Based on 12 years of demographic data for a pioneer tree species(Pinus massoniana)censused in three plots that correspond to three stages of ecological restoration in south-eastern China.We built integral projection models(IPMs)to assess vital rates(survival,growth,reproduction)and population growth in each plot,then evaluated demographic changes to simulated changes in seasonal mean temperature and precipitation in the current and previous census period.The plot representing the medium restoration stage had the highest population growth rate(λ=0.983).Mean population survival probability increased with ecological restoration,and reproduction probability was significantly suppressed at the high restoration stage.Survival is always the most important vital rate forλ,and climate affectsλprimarily via survival at each restoration stage.The current spring tem-perature was the most critical climate variable forλin the low and medium restoration stages,and previous summer temperature was most critical in the high restoration stage.Simulated warming leads to a decrease in the stochastic population growth rate(λ_(s))of P.massoniana in every stage.These findings suggest that during ecological restoration,P.massoniana responds to habitat change via modified demo-graphic performance,thus altering its response to climate change.Despite diverse responses to climate change,the persistence of P.massoniana populations is facing a wide-spread threat of warming states at each restoration stages.
基金This work was supported by the Qinchuangyuan Project of Shaanxi Province,China(QCYRCXM-2022-145)the Major Project of the Key Research Base of Humanities and Social Sciences of the Ministry of Education,China(22JJD790052)+1 种基金the Chinese Universities Scientific Fund(Z1010422003)the National Natural Science Foundation of China(72373117).
文摘With increasing population and changing demographics,food consumption has experienced a significant transition in quantity and quality.However,a dearth of knowledge remains regarding its environmental impacts and how it responds to demographic dynamics,particularly in emerging economies like China.Using the two-stage Quadratic Almost Demand System(QUAIDS)model,this study empirically examines the impact of demographic dynamics on food consumption and its environmental outcomes based on the provincial data from 2000 to 2020 in China.Under various scenarios,according to changes in demographics,we extend our analysis to project the long-term trend of food consumption and its environmental impacts,including greenhouse gas(GHG)emissions,water footprint(WF),and land appropriation(LA).The results reveal that an increase in the proportion of senior people significantly decreases the consumption of grain and livestock meat and increases the consumption of poultry,egg,and aquatic products,particularly for urban residents.Moreover,an increase in the proportion of males in the population leads to higher consumption of poultry and aquatic products.Correspondingly,in the current scenario of an increased aging population and sex ratio,it is anticipated that GHG emissions,WF,and LA are likely to decrease by 1.37,2.52,and 3.56%,respectively.More importantly,in the scenario adhering to the standards of nutritional intake according to the Dietary Guidelines for Chinese Residents in 2022,GHG emissions,WF,and LA in urban areas would increase by 12.78,20.94,and 18.32%,respectively.Our findings suggest that changing demographics should be considered when designing policies to mitigate the diet-environment-health trilemma and achieve sustainable food consumption.
基金supported by the National Key R&D Program of China(2020YFC2003102).
文摘Objective:To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in China.Methods: Elderly individuals from seven regions in China were selected as samples in this study using a multistage cluster random sampling method.The basic information questionnaire and Constitution in Chinese Medicine Questionnaire(Elderly Edition)were used.Descriptive statistical analysis,chi-squared tests,and binary logistic regression analysis were used.Results: The single balanced constitution(BC)accounted for 23.9%.The results of the major TCM constitution types showed that BC(43.2%)accounted for the largest proportion and unbalanced constitutions ranged from 0.9%to 15.7%.East China region(odds ratio[OR]=2.097;95%confidence interval[CI],1.912 to 2.301),married status(OR=1.341;95%CI,1.235 to 1.457),and managers(OR=1.254;95%CI,1.044 to 1.505)were significantly associated with BC.Age>70 years was associated with qi-deficiency constitution and blood stasis constitution(BSC).Female sex was significantly associated with yang-deficiency constitution(OR=1.646;95%CI,1.52 to 1.782).Southwest region was significantly associated with phlegm-dampness constitution(OR=1.809;95%CI,1.569 to 2.086).North China region was significantly associated with inherited special constitution(OR=2.521;95%CI,1.569 to 4.05).South China region(OR=2.741;95%CI,1.997 to 1.3.763),Central China region(OR=8.889;95%CI,6.676 to 11.835),senior middle school education(OR=2.442;95%CI,1.932 to 3.088),and managers(OR=1.804;95%CI,1.21 to 2.69)were significantly associated with BSC.Conclusions: This study defined the distribution characteristics and demographic factors of TCM constitution in the elderly population.Adjusting and improving unbalanced constitutions,which are correlated with diseases,can help promote healthy aging through the scientific management of these demographic factors.
基金supported by the Ministry of Science and Higher Education of the Russian Federation(No.075-152021-1037,Internal No.15.BRK.21.0001)。
文摘The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse origin.This study was a large-scale genome-wide analysis of the landscape of the complex molecular architecture,genetic variability,and detailed structure among 49 populations.These populations represent a significant sample of the world's chicken breeds from Europe(Russia,Czech Republic,France,Spain,UK,etc.),Asia(China),North America(USA),and Oceania(Australia).Based on the results of breed genotyping using the Illumina 60K single nucleotide polymorphism(SNP)chip,a bioinformatic analysis was carried out.This included the calculation of heterozygosity/homozygosity statistics,inbreeding coefficients,and effective population size.It also included assessment of linkage disequilibrium and construction of phylogenetic trees.Using multidimensional scaling,principal component analysis,and ADMIXTURE-assisted global ancestry analysis,we explored the genetic structure of populations and subpopulations in each breed.An overall 49-population phylogeny analysis was also performed,and a refined evolutionary model of chicken breed formation was proposed,which included egg,meat,dual-purpose types,and ambiguous breeds.Such a large-scale survey of genetic resources in poultry farming using modern genomic methods is of great interest both from the viewpoint of a general understanding of the genetics of the domestic chicken and for the further development of genomic technologies and approaches in poultry breeding.In general,whole genome SNP genotyping of promising chicken breeds from the worldwide gene pool will promote the further development of modern genomic science as applied to poultry.
文摘“Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy makers.The rising conflict between human beings and wild elephants is common in Buxa Tiger Reserve(BTR)and its adjoining area in West Bengal State,India,making the area volatile.People’s attitudes towards elephant conservation activity are very crucial to get rid of HEC,because people’s proximity with wild elephants’habitat can trigger the occurrence of HEC.The aim of this study is to conduct an in-depth investigation about the association of people’s attitudes towards HEC with their locational,demographic,and socio-economic characteristics in BTR and its adjoining area by using Pearson’s bivariate chi-square test and binary logistic regression analysis.BTR is one of the constituent parts of Eastern Doors Elephant Reserve(EDER).We interviewed 500 respondents to understand their perceptions to HEC and investigated their locational,demographic,and socio-economic characteristics including location of village,gender,age,ethnicity,religion,caste,poverty level,education level,primary occupation,secondary occupation,household type,and source of firewood.The results indicate that respondents who are living in enclave forest villages(EFVs),peripheral forest villages(PFVs),corridor village(CVs),or forest and corridor villages(FCVs),mainly males,at the age of 18–48 years old,engaged with agriculture occupation,and living in kancha and mixed houses,have more likelihood to witness HEC.Besides,respondents who are illiterate or at primary education level are more likely to regard elephant as a main problematic animal around their villages and refuse to participate in elephant conservation activity.For the sake of a sustainable environment for both human beings and wildlife,people’s attitudes towards elephants must be friendly in a more prudent way,so that the two communities can live in harmony.
文摘BACKGROUND The Limb Lengthening and Reconstruction Society(LLRS)is a premier orthopedic specialty organization that promotes limb reconstruction for all ages.LLRS membership characteristics,however,are poorly reported.This study delineates orthopedic surgeon LLRS members’demographic traits,academic achievement,leadership attainment,and geographical distribution across the United States.AIM To inform aspiring orthopedic professionals,as well as to promote growth and diversity in both the LLRS organization and overarching field.METHODS This cross-sectional study examined United States LLRS members’academic,leadership,demographic,and geographical attributes.After reviewing the 2023 LLRS member directory,Google search results were matched to the listings and appended to the compiled data.Sex and ethnicity were evaluated visually utilizing retrieved images.The Hirsch index(H-index)of academic activity,residency and fellowship training,other graduate degrees,leadership positions,practice type(academic or non-academic),and spoken languages were categorized.LLRS members per state and capita determined geographic distribution.The Mann Whitney U test was applied to compare H-index between males and females,as well as to assess member differences pertaining to affiliation with academic vs non-academic practice facilities.RESULTS The study included 101 orthopedic surgeons,78(77.23%)Caucasian and 23(22.77%)non-Caucasian,79(78.22%)male and 22(21.78%)female.Surgeons with DO degrees comprised only 3.96%(4)of the cohort,while the vast majority held MDs[96.04%(97)].Mean H-index was 10.55,with male surgeons having a significantly higher score(P=0.002).Most orthopedic surgeons(88.12%,)practiced in academic centers.Of those professionals who occupied leadership positions,14%were women,while 86%were men.Additionally,19(37.25%)United States regions and the District of Columbia lacked an LLRS-member orthopedic surgeon.Total per capita rate across the United States was 0.30 LLRS orthopedic surgeons per 1 million people.CONCLUSION Over 21%of LLRS members are women,surpassing prior benchmarks noted in orthopedic faculty reporting.LLRS members’high research productivity scores imply field dedication that can refine expertise in the limb lengthening and reconstruction space.Gender disparities in leadership remain,however,necessitating greater equity efforts.A low rate of LLRS representation per capita must be addressed geographically as well,to affect improvements in regional care access.This study can serve to support aspiring orthopedic professionals,inform diversity,leadership,and field advancement strategies,and maintain the continued goal of enhanced patient care worldwide.
文摘Background: In Sub-Saharan Africa, pre-eclampsia remains a major health problem contributing to high rates of maternal mortality. Despite this condition having adverse effects on maternal and child health, its prevalence and associated risk factors are still significant, especially in developing countries including Ghana. This study aimed to assess the prevalence and demographic distributions associated with pre-eclampsia among pregnant women at the Ho Teaching Hospital. Methods: A facility-based retrospective study was conducted by reviewing available data or hospital records of pregnant mothers admitted to the labor and maternity wards from January 2018 to December 2020. All pregnant women who were diagnosed with pre-eclampsia within this period were included in the study. The data were collected using a structured checklist. Results: 5609 data on pregnant women from 2018 to 2020 were recorded. Out of the 5609 data recorded, 314 pre-eclampsia cases were recorded giving an overall prevalence of 5.6%. The yearly prevalence for 2018, 2019, and 2020 were 4.6%, 5.6%, and 6.6%, respectively. The most recorded pre-eclampsia cases were seen among women within the age group of 18 - 24 years. The data showed that 112 (35.7%) of the pregnant women who had pre-eclampsia were nulliparous. Pre-eclampsia-associated maternal and fetal complications were;preterm delivery 221 (70.4%), intrauterine fetal death 62 (19.7%), eclampsia 9 (2.9%), HELLP syndrome 5 (1.6%) and maternal death 17 (5.4%). Associated factors of pre-eclampsia were parity, level of education, and occupation (p ≤ 0.05). Conclusion: The findings of this study showed a rising trend in the incidence of pre-eclampsia over the years at the Ho Teaching Hospital. Parity, level of education, and occupation were found to be associated with developing pre-eclampsia.
文摘Globally,population dynamics are shifting towards increased life expectancy,and many countries,including Greece,face significant demographic challenges.Greece is particularly impacted by one of the lowest birth rates in the world and a rapidly aging population.This demographic shift places unprecedented pressure on the nation’s pension systems and economic stability,as more people retire than enter the workforce.This study aims to explore the historical factors contributing to Greece’s demographic situation,analyze the consequences of current trends,and propose strategic solutions.The research utilizes a literature review approach and the case study of Greece to understand the depth and breadth of the demographic crisis.Key areas of focus include the declining birth rate,the economic implications of an aging population,and the potential of migration and policy reform to rejuvenate demographic dynamics.The study evaluates various policy interventions from other countries to propose a tailored,multi-faceted strategy for Greece.These strategies emphasize economic incentives for young families,improved childcare and parental support,healthcare investment,and inclusive migration policies to enhance workforce numbers.This comprehensive approach seeks to provide actionable insights that can help Greece mitigate the effects of demographic decline and foster a more sustainable future,aligning policy interventions with socio-economic and cultural realities.
基金supported by the Guangzhou Science and Technology Project(no.2023B03J1232)National Natural Science Foundation of China(82301036)+1 种基金Special Funds for the Cultivation of Guangdong College Students’Scientific and Technological Innovation(no.pdjh2023b0013)Undergraduate Training Program for Innovation of Sun Yat-sen University(20240518).
文摘Objective and Impact Statement:The multi-quantification of the distinct individualized maxillofacial traits,that is,quantifying multiple indices,is vital for diagnosis,decision-making,and prognosis of the maxillofacial surgery.Introduction:While the discrete and demographically disproportionate distributions of the multiple indices restrict the generalization ability of artificial intelligence(AI)-based automatic analysis,this study presents a demographic-parity strategy for AI-based multi-quantification.Methods:In the aesthetic-concerning maxillary alveolar basal bone,which requires quantifying a total of 9 indices from length and width dimensional,this study collected a total of 4,000 cone-beam computed tomography(CBCT)sagittal images,and developed a deep learning model composed of a backbone and multiple regression heads with fully shared parameters to intelligently predict these quantitative metrics.Through auditing of the primary generalization result,the sensitive attribute was identified and the dataset was subdivided to train new submodels.Then,submodels trained from respective subsets were ensembled for final generalization.Results:The primary generalization result showed that the AI model underperformed in quantifying major basal bone indices.The sex factor was proved to be the sensitive attribute.The final model was ensembled by the male and female submodels,which yielded equal performance between genders,low error,high consistency,satisfying correlation coefficient,and highly focused attention.The ensemble model exhibited high similarity to clinicians with minor processing time.Conclusion:This work validates that the demographic parity strategy enables the AI algorithm with greater model generalization ability,even for the highly variable traits,which benefits for the appearance-concerning maxillofacial surgery.
文摘A great discovery made by H. von Foerster, P. M. Mora and L. W. Amiot was published in a 1960 issue of “Science”. The authors showed that existing data for calculating the Earth’s population in the new era (from 1 to 1958) could be described with incredibly high proximity by a hyperbolic function with the point of singularity on 13 November 2026. Thus, empirical regularity of the rise of the human population was established, which was marked by explosive demographic growth in the 20<sup>th</sup> century when during only one century it almost quadrupled: from 1.656 billion in 1900 to 6.144 billion in 2000. Nowadays, the world population has already overcome 7.8 billion people. Immediately after 1960, an active search for phenomenological models began to explain the mechanism of the hyperbolic population growth and the following demographic transition designed to stabilize its population. A significant role in explaining the mechanism of the hyperbolic growth of the world population was played by S. Kuznets (1960) and E. Boserup (1965), who found out that the rates of technological progress historically increased in proportion to the Earth’s population. It meant that the growth of the population led to raising the level of life-supporting technologies, and the latter in its turn enlarged the carrying capacity of the Earth, making it possible for the world population to expand. Proceeding from the information imperative, we have developed the model of the demographic dynamics for the 21<sup>st</sup> century for the first time. The model shows that with the development and spread of Intelligent Machines (IM), the number of the world population reaching a certain maximum will then irreversibly decline. Human depopulation will largely touch upon the most developed countries, where IM is used intensively nowadays. Until a certain moment in time, this depopulation in developed countries will be compensated by the explosive growth of the population in African countries located south of the Sahara. Calculations in our model reveal that the peak of the human population of 8.52 billion people will be reached in 2050, then it will irreversibly go down to 7.9 billion people by 2100, if developed countries do not take timely effective measures to overcome the process of information depopulation.
文摘The decline in the birth rate,which has been uninterrupted in Italy since the mid-1960s,has had a significant impact on many aspects of society.As far as the educational system is concerned,this phenomenon has acted like a wave,first causing a decline in the population of the first school age groups,then in the other groups,until recently affecting the 19-25 age group,which includes the majority of university students.As a result,the majority of Italian universities have seen a decline over time in both enrollments(matriculations)and student numbers(enrollments),although the situation varies from one area to another.In the Mezzogiorno,this trend is even more pronounced,since an increasing number of resident students tend to favor universities in the Centre-North,creating a South-Centre-North movement,which could be compared to a particular form of cultural tourism,without a similar flow in the opposite direction.Finally,the study highlights the probable consequences of the recent demographic depopulation on the future trend of university enrollment of residents aged 19-25 in the Calabria region,using the most recent demographic projections of Istat and constructing two evolutionary scenarios.In the first scenario,we have assumed that in the near future university enrollment rates remain constant throughout the period considered;in the second scenario,these rates instead experience a gradual and continuous increase.These results could be useful if further forecasts of university enrollments were to be made at the level of individual Calabrian universities.
文摘Given the great strides that China＇s education sector has made in recent decades, it can be expected that the overall workforce quality of exiting China＇s labor market in coming one or two decades will be relatively low, while the overall quality of workforce newly entering into China＇s labor market will be high. As the new, bettereducated generation takes over, China＇s workforce quality will be vastly improved. This in turn will promote economic growth. We refer to economic growth arising from improved workforce quality as qualitative demographic dividend. Using the computable general equilibrium （CGE） model, this paper investigates the relationship between workforce quality improvements and economic growth. According to the model＇s results, an improvement in workforce quality will raise the economic growth rate by about two percentage points per annum between 2016 and 2020 and by 10 percentage points cumulatively by 2020. In other words, GDP will be 1.1 times the level of baseline GDP by 2020 due to the improved education levels. Given different production functions across sectors, the improvement of workforce quality will affect different sectors in different ways. On the whole, the improvement of workforce quality is more favorable to the development of capital-intensive sectors and sectors with rapid technology progress. According to this paper, considering the improvement of workforce quality, we cannot conclude that China＇s potential economic growth rate has already begun to decline. Despite diminishing conventional quantitative demographic dividends, China ＂s qualitative demographic dividends will keep rising. Qualitative demographic dividends will further push forward China＇s industrial restructuring and the strategic transition of industrial competitiveness from quantitative to qualitative and from an extensive to an intensive pattern of development.
基金Supported by the National Social Science Fund of China(13XSH017)~~
文摘[Objective] The aim was to analyze the phenomenon of employment diffi- culty and labor shortage, and to reveal the influencing factors of employment difli- culty and labor shortage. [Method] On the basis of the economic principle of popu- lation dividend, the use of human resources and natural resource constraints The IS-LM model describes these two states. [Results] The resource constraints have a ＂squeeze＂ effect on the demographic dividend, and employment pressure is shown in terms of the population opportunity window; the labor market segmentation, the ir- rational industrial structure, the backward curriculum and employment concept are the main factors affecting employment and labor shortage. [Conclusion] The way to solve this dilemma must be removed from the division of labor market, the adjust- ment of industrial structure, the setting of university specialty, the change of em- ployment concept of university graduates as well as the improvement of the quality of labor.
