The actual circumstances of daily life are crucial for the purchasing and pricing strategies of supermarkets.Developing strategies based on these circumstances can assist businesses in ensuring profits and fostering w...The actual circumstances of daily life are crucial for the purchasing and pricing strategies of supermarkets.Developing strategies based on these circumstances can assist businesses in ensuring profits and fostering win-win cooperation.This paper explores methods to maximize profit through purchasing and sales strategies.Initially,the relevant data for various categories of vegetables is integrated.Through histograms,their sales patterns are directly understood,highlighting the most popular vegetables.Upon analyzing each vegetable category,it becomes evident that their sales data do not conform to normal distributions.Therefore,Spearman correlation coefficients are calculated,revealing strong correlations between certain categories,such as aquatic roots and edible fungi.A line chart depicting the top ten selling vegetables indicates a noticeable periodicity.Traditional fitting methods struggle to adequately model the sales of each vegetable category and their relationship with cost-plus pricing.To address this,additional factors such as holidays,weeks,and months are incorporated using techniques like random forest regression.This approach yields cost-plus pricing dependence curves that better capture the relationship,while effectively managing noise.Regarding sales volume prediction,the original data displays significant volatility,necessitating the handling of outliers using the threshold method.For missing data,linear interpolation is employed to mitigate the impact of continuous missing values on prediction accuracy.Subsequently,Adam-optimized long short-term memory(LSTM)networks are utilized to forecast incoming quantities for the next seven days.By extrapolating from normal sales volume,market capacity is estimated,allowing for additional sales through discount strategies.This framework has the potential to increase original income by 1.1 times.展开更多
Clear aligner treatment is a novel technique in current orthodontic practice.Distinct from traditional fixed orthodontic appliances,clear aligners have different material features and biomechanical characteristics and...Clear aligner treatment is a novel technique in current orthodontic practice.Distinct from traditional fixed orthodontic appliances,clear aligners have different material features and biomechanical characteristics and treatment efficiencies,presenting new clinical challenges.Therefore,a comprehensive and systematic description of the key clinical aspects of clear aligner treatment is essential to enhance treatment efficacy and facilitate the advancement and wide adoption of this new technique.This expert consensus discusses case selection and grading of treatment difficulty,principle of clear aligner therapy,clinical procedures and potential complications,which are crucial to the clinical success of clear aligner treatment.展开更多
Urbanization and industrialization have escalated water pollution,threatening ecosystems and human health.Water pollution not only degrades water quality but also poses long-term risks to human health through the food...Urbanization and industrialization have escalated water pollution,threatening ecosystems and human health.Water pollution not only degrades water quality but also poses long-term risks to human health through the food chain.The development of efficient wastewater detection and treatment methods is essential for mitigating this environmental hazard.Carbon dots(CDs),as emerging carbon-based nanomaterials,exhibit properties such as biocompatibility,photoluminescence(PL),water solubility,and strong adsorption,positioning them as promising candidates for environmental monitoring and management.Particularly in wastewater treatment,their optical and electron transfer properties make them ideal for pollutant detection and removal.Despite their potential,comprehensive reviews on CDs'role in wastewater treatment are scarce,often lacking detailed insights into their synthesis,PL mechanisms,and practical applications.This review systematically addresses the synthesis,PL mechanisms,and wastewater treatment applications of CDs,aiming to bridge existing research gaps.It begins with an overview of CDs structure and classification,essential for grasping their properties and uses.The paper then explores the pivotal PL mechanisms of CDs,crucial for their sensing capabilities.Next,comprehensive synthesis strategies are presented,encompassing both top-down and bottom-up strategies such as arc discharge,chemical oxidation,and hydrothermal/solvothermal synthesis.The diversity of these methods highlights the potential for tailored CDs production to suit specific environmental applications.Furthermore,the review systematically discusses the applications of CDs in wastewater treatment,including sensing,inorganic removal,and organic degradation.Finally,it delves into the research prospects and challenges of CDs,proposing future directions to enhance their role in wastewater treatment.展开更多
Ischemic stroke is a major cause of neurological deficits and high disability rate.As the primary immune cells of the central nervous system,microglia play dual roles in neuroinflammation and tissue repair following a...Ischemic stroke is a major cause of neurological deficits and high disability rate.As the primary immune cells of the central nervous system,microglia play dual roles in neuroinflammation and tissue repair following a stroke.Their dynamic activation and polarization states are key factors that influence the disease process and treatment outcomes.This review article investigates the role of microglia in ischemic stroke and explores potential intervention strategies.Microglia exhibit a dynamic functional state,transitioning between pro-inflammatory(M1)and anti-inflammatory(M2)phenotypes.This duality is crucial in ischemic stroke,as it maintains a balance between neuroinflammation and tissue repair.Activated microglia contribute to neuroinflammation through cytokine release and disruption of the blood-brain barrier,while simultaneously promoting tissue repair through anti-inflammatory responses and regeneration.Key pathways influencing microglial activation include Toll-like receptor 4/nuclear factor kappa B,mitogen-activated protein kinases,Janus kinase/signal transducer and activator of transcription,and phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathways.These pathways are targets for various experimental therapies aimed at promoting M2 polarization and mitigating damage.Potential therapeutic agents include natural compounds found in drugs such as minocycline,as well as traditional Chinese medicines.Drugs that target these regulatory mechanisms,such as small molecule inhibitors and components of traditional Chinese medicines,along with emerging technologies such as single-cell RNA sequencing and spatial transcriptomics,offer new therapeutic strategies and clinical translational potential for ischemic stroke.展开更多
Wire-arc directed energy deposition(wire-arc DED)enables the fabrication of large-scale metal components with rapid manufacturing ability and diverse material selection,making it a compelling technology in industries ...Wire-arc directed energy deposition(wire-arc DED)enables the fabrication of large-scale metal components with rapid manufacturing ability and diverse material selection,making it a compelling technology in industries and defenses.However,challenges in both macroscale and microscale defects still limit printed component widespread applications.Recent advances in automatic and intelligent technologies have brought a range of quality controllable strategies to the forefront.This review covers these new strategies for the printing component,including path planning,process monitoring,auxiliary processes,and post processing,while discussing the expectation for structure and quality improvement.In addition,the work brings new areas of intelligent wire-arc DED development,including advances in digital twin,visualization,and human-processing interaction to promote its performance.It is anticipated that a focus on intelligent system will be key to smart and high-quality manufacturing for future wire-arc DED.展开更多
This study aims to explore the characteristics of novice teachers’inappropriate behaviors in classroom teaching and their intervention strategies.With the continuous improvement of education quality,novice teachers f...This study aims to explore the characteristics of novice teachers’inappropriate behaviors in classroom teaching and their intervention strategies.With the continuous improvement of education quality,novice teachers face increasing challenges in teaching practice.Their inappropriate behaviors not only affect the classroom atmosphere but may also negatively impact students’learning outcomes.Therefore,researching the characteristics of novice teachers’inappropriate behaviors and their intervention strategies holds significant scientific and social value.This study employs a combination of quantitative and qualitative methods to analyze the behavioral patterns of novice teachers in classroom teaching and proposes corresponding intervention strategies.The results indicate that novice teachers’inappropriate behaviors mainly manifest as poor classroom management,monotonous teaching methods,and insufficient interaction with students.Based on these findings,the study proposes a series of effective intervention strategies,including enhancing teacher training,optimizing teaching design,and promoting positive interactions between teachers and students.The conclusions of the study not only provide practical guidance for educational practice but also point out directions for future research,emphasizing the crucial role of teacher professional development in improving teaching quality.展开更多
Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug...Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug discovery but also inspire innovative strategies in drug development.The biomimetic synthesis of natural products employs principles from biomimicry,applying inspiration from biogenetic processes to design synthetic strategies that mimic biosynthetic processes.Biomimetic synthesis is a highly efficient approach in synthetic chemistry,as it addresses critical challenges in the synthesis of structurally complex natural products with significant biological and medicinal importance.It has gained widespread attention from researchers in chemistry,biology,pharmacy,and related fields,underscoring its interdisciplinary impact.In this perspective,we present recent advances and challenges in the biomimetic synthesis of natural products,along with the significance and prospects of this field,highlighting the transformative potential of biomimetic synthesis strategies for both chemical and biosynthetic approaches to natural product synthesis in the pursuit of novel therapeutic agents.展开更多
The growing need for higher energy density in rechargeable batteries necessitates the exploration of cathode materials with enhanced specific energy for lithium-ion batteries.Due to their exceptional cost-effectivenes...The growing need for higher energy density in rechargeable batteries necessitates the exploration of cathode materials with enhanced specific energy for lithium-ion batteries.Due to their exceptional cost-effectiveness and specific capacity,lithium-rich manganese-based cathode materials(LRMs)obtain in-creasing attention in the pursuit of enhancing energy density and reducing costs.The implementation has faced obstacles in various applications due to substantial capacity and voltage degradation,insufficient safety performance,and restricted rate capability during cycling.These issues arise from the migration of transition metal,the release of oxygen,and structural transformation.In this review,we provide an integrated survey of the structure,lithium storage mechanism,challenges,and origins of LRMs,as well as recent advancements in various coating strategies.Particularly,the significance of optimizing the design of the cathode electrolyte interphase was emphasized to enhance electrode performance.Furthermore,future perspective was also addressed alongside in-situ measurements,advanced synthesis techniques,and the application of machine learning to overcome encountered challenges in LRMs.展开更多
Climate change is accelerating globally,raising significant concerns regarding the environmental risks associated with combined sewer overflows(CSOs).These rainfall events lead to the excessive discharge of multiple p...Climate change is accelerating globally,raising significant concerns regarding the environmental risks associated with combined sewer overflows(CSOs).These rainfall events lead to the excessive discharge of multiple pollutants into natural waters.However,greenhouse gas(GHG)emissions from CSOs,which are crucial for carbon neutrality in urban water systems,remain fragmented.Using the life-cycle assess-ment method expansion approach,this study breaks down the formation and discharge processes of CSOs and uncovers the underlying mechanisms driving GHG emissions during each period.Given the complex-ity and uncertainty in the spatial distribution of GHG emissions from CSOs,the development of standard monitoring and estimation methods is vital.This study identifies the factors influencing GHG emissions within the urban drainage system(UDS)and defines the interactive GHG emission boundaries and accounting framework related to CSOs.This framework is expanded to consider the hybrid nature of urban engineering and hydraulic interactions during the CSO events.Advanced modeling technologies have emerged as essential tools for predicting and managing GHG emissions from CSOs.This review pro-motes comprehensive data-driven methods for predicting GHG emissions from CSOs,fully considering the inherent heterogeneity of CSOs and the impact of multi-source contaminants discharged into aquatic environments.It emphasizes refining emission boundary definitions,novel accounting practices adapting data-driven methods,and comprehensive management strategies in line with the move toward carbon neutrality in the UDS.It advocates the adoption of solutions including advanced technologies and artifi-cial intelligent methods to mitigate CSO-related GHG emissions,stressing the significance of integrating low-carbon solutions and a comprehensive data-driven management framework in future research directions.展开更多
Pitch is a complex mixture of polycyclic aromatic hydrocarbons and their non-metal derivatives that has a high carbon content.Using pitch as a precursor for carbon materials in alkali metal ion(Li^(+)/Na^(+)/K^(+))bat...Pitch is a complex mixture of polycyclic aromatic hydrocarbons and their non-metal derivatives that has a high carbon content.Using pitch as a precursor for carbon materials in alkali metal ion(Li^(+)/Na^(+)/K^(+))batteries has become of great interest.However,its direct pyrolysis often leads to microstructures with a high orientation and small interlayer spacing due to uncontrolled liquid-phase carbonization,resulting in subpar electrochemical performance.It is therefore important to control the microstructures of pitch-derived carbon materials in order to improve their electrochemical properties.We evaluate the latest progress in the development of these materials using various microstructural engineering approaches,highlighting their use in metal-ion batteries and supercapacitors.The advantages and limitations of pitch molecules and their carbon derivatives are outlined,together with strategies for their modification in order to improve their properties for specific applications.Future research possibilities for structure optimization,scalable production,and waste pitch recycling are also considered.展开更多
We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponen...We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponential distributions.Whenever the server is available,it admits the retrial customers into service based on a first-come first-served rule.The service rate adjusts in real-time based on the retrial queue length.An iterative algorithm is proposed to numerically solve the personal optimal problem in the fully observable scenario.Furthermore,we investigate the impact of parameters on the social optimal threshold.The effectiveness of the results is illustrated by two examples.展开更多
In this paper,based on the structure-behavior coupling paradigm,we propose the concept of deviation of central town to describe the geography-market distance between farmers and the central regional town.Using the sur...In this paper,based on the structure-behavior coupling paradigm,we propose the concept of deviation of central town to describe the geography-market distance between farmers and the central regional town.Using the survey data from farmers in a poverty-stricken village in Western China,the impact of deviation of central town on farmers'livelihood strategies is analyzed.The results indicate that farmers exhibit spatial heterogeneity in their livelihood strategies.Those with low deviation show a strong inclination towards working in urban areas,while those with high deviation tend to integrate into rural industries.The deviation of central town influences farmers'livelihood strategies through the information effect,which is also affected by the level of rural infrastructure and public services,labor force structure and assistance policies.The obtained results are expected to provide guidance for promoting the integration of farmers into the urban-rural economic cycle based on sustainable livelihoods and connecting poverty alleviation with rural revitalization.展开更多
Agriculture has become the backbone of most developing countries in the world, especially Tubah Sub-Division North West region, Cameroon. Following the COVID-19 pandemic and socio-political crisis that hit Cameroon’s...Agriculture has become the backbone of most developing countries in the world, especially Tubah Sub-Division North West region, Cameroon. Following the COVID-19 pandemic and socio-political crisis that hit Cameroon’s economy, there has been a steady increase in food insecurity, which has paved the way for farmers to adopt some sustainable strategies to boost agricultural productivity. Therefore, in trying to find models for survival and the pursuit of growth, farmers adopted some traditional farming methods and the use of local input as a means of sustainability. This study specifically seeks to analyze the effect of sustainability strategies on agricultural productivity in Tubah sub-division North West Region, Cameroon. The data was elicited via a survey questionnaire administered to 202 participating farmers selected from the different farmer organizations in the Tubah sub-division. Using cluster-sampling approach, proximity villages were grouped into four clusters of villages, and stratified sampling was used to select farmers to participate in the study. The objective of the study was achieved using OLS and quantile regression estimation techniques. The result showed evidence that the sustainability strategies implemented by the farmers decreased agricultural productivity in the 25th quantile, and at the 50th and 75th quantile, agricultural productivity still declined. This decline is because of unsustainable agricultural strategies like the use of slash and burn, the use of chemical fertilizers, inadequate capital, low level of education, inadequate farming experience, inadequate income, inadequate farm size, and the type of technology used for farming. Based on the findings, this study recommends that the government should organize training programs and seminars, subsidize farm inputs, grant agricultural loans to farmers, and initiate and support mechanized agriculture to boost agricultural productivity.展开更多
Neural injuries can cause considerable functional impairments,and both central and peripheral nervous systems have limited regenerative capacity.The existing conventional pharmacological treatments in clinical practic...Neural injuries can cause considerable functional impairments,and both central and peripheral nervous systems have limited regenerative capacity.The existing conventional pharmacological treatments in clinical practice show poor targeting,rapid drug clearance from the circulatory system,and low therapeutic efficiency.Therefore,in this review,we have first described the mechanisms underlying nerve regeneration,characterized the biomaterials used for drug delivery to facilitate nerve regeneration,and highlighted the functionalization strategies used for such drug-delivery systems.These systems mainly use natural and synthetic polymers,inorganic materials,and hybrid systems with advanced drug-delivery abilities,including nanoparticles,hydrogels,and scaffoldbased systems.Then,we focused on comparing the types of drug-delivery systems for neural regeneration as well as the mechanisms and challenges associated with targeted delivery of drugs to facilitate neural regeneration.Finally,we have summarized the clinical application research and limitations of targeted delivery of these drugs.These biomaterials and drug-delivery systems can provide mechanical support,sustained release of bioactive molecules,and enhanced intercellular contact,ultimately reducing cell apoptosis and enhancing functional recovery.Nevertheless,immune reactions,degradation regulation,and clinical translations remain major unresolved challenges.Future studies should focus on optimizing biomaterial properties,refining delivery precision,and overcoming translational barriers to advance these technologies toward clinical applications.展开更多
Background:The academic community is increasingly interested in understanding the mechanisms through which gratitude influences coping strategies.In addition,the role of gratitude in fostering long-term resilience and...Background:The academic community is increasingly interested in understanding the mechanisms through which gratitude influences coping strategies.In addition,the role of gratitude in fostering long-term resilience and mental health outcomes has garnered significant attention.This study explores the mechanisms through which gratitude affects problem-focused coping strategies and emotion-focused coping strategies by constructing models involving gratitude,perceived social support,self-esteem,and problem-focused coping strategies,as well as models involving gratitude,perceived social support,self-esteem,and emotion-focused coping strategies.Methods:A longitudinal survey was conducted on 1666 Chinese university students using highly reliable and valid scales,including the Gratitude Scale,Perceived Social Support Scale,Self-Esteem Scale,and Brief Coping Strategies Scale.To examine whether perceived social support and self-esteem play a significant indirect role in the relationship between gratitude and problem-focused coping strategies,as well as between gratitude and emotion-focused coping strategies.Differences in variables based on demographic variables:We used one-way ANOVA to test the differences in gratitude,perceived social support,self-esteem,problem-focused coping strategies,and emotion-focused coping strategies among students of different grades and ages.Additionally,independent samples t-tests were used to examine the differences between students of different genders and household registrations.Results:The study found that(1)Gratitude significantly positively predicted perceived social support(β=0.661,p<0.001),self-esteem(β=0.234,p<0.001),and problemfocused coping strategies(β=0.130,p<0.001);(2)Perceived social support significantly positively predicted self-esteem(β=0.440,p<0.001;β=0.439,p<0.001),problem-focused coping strategies(β=0.443,p<0.001),and emotion-focused coping strategies(β=0.279,p<0.001);(3)Self-esteem significantly positively predicted problem-focused coping strategies(β=0.172,p<0.001)and significantly negatively predicted emotion-focused coping strategies(β=−0.205,p<0.001);(4)Gratitude can influence problem-focused coping strategies through the dual indirect effect of two mediating variables.After the inclusion of the mediating variables,the effect of problem-focused coping strategies in the indirect model was further strengthened.(5)Gratitude can influence emotion-focused coping strategies through a completely indirect effect on perceived social support and self-esteem.After inserting the mediating variables,the effect of emotionfocused coping strategies in the mediating model is enhanced.Conclusion:Gratitude can directly and positively predict problem-focused coping strategies,and it can also positively predict problem-focused coping strategies through the dual indirect effect of two mediating variables.Gratitude does not significantly predict emotion-focused coping strategies directly,but it can influence emotion-focused coping strategies via a double indirect pathway.展开更多
This article focuses on the challenges of rural economic development under the strategy of rural revitalization,and deeply analyzes the current situation of rural economic development.Research has found that although ...This article focuses on the challenges of rural economic development under the strategy of rural revitalization,and deeply analyzes the current situation of rural economic development.Research has found that although the rural revitalization strategy has achieved significant results in improving residents’quality of life,promoting agricultural modernization,it still faces challenges such as severe loss of human resources,insufficient agricultural technological innovation,and backward infrastructure construction.In response to these challenges,this paper proposes optimization strategies from three aspects:strengthening rural education and talent team construction,promoting agricultural technology innovation and achievement transformation,and increasing investment in rural infrastructure construction.展开更多
The interplay of academic atmosphere,learning motivation,and strategies inherently influences English learning.Effective vocabulary acquisition strategies significantly influence the achievements of English acquisitio...The interplay of academic atmosphere,learning motivation,and strategies inherently influences English learning.Effective vocabulary acquisition strategies significantly influence the achievements of English acquisition.Vocabulary mastery,a cornerstone of middle school English education,raises a critical question:How can vocabulary strategies optimize students’memory,understanding,and vocabulary application?This article elaborates on the importance and characteristics of vocabulary learning in Chinese junior high schools,analyzes definitions and theories of learning strategies,and proposes specific vocabulary approaches tailored to junior high school students in rural-urban fringe areas.展开更多
Toluene is widely used as a raw material for many chemical products/pharmaceutical intermediates and as a solvent in many chemical and manufacturing industries.The conversion of toluene into higher value chemicals(ben...Toluene is widely used as a raw material for many chemical products/pharmaceutical intermediates and as a solvent in many chemical and manufacturing industries.The conversion of toluene into higher value chemicals(benzyl alcohol,benzaldehyde,and benzoic acid,etc.)using sunlight is a very promising means.To achieve the full conversion and utilization of toluene,it is necessary to construct photocatalysts with high conversion and selectivity while synergistically optimizing the optimal reaction environment to significantly affect the photo-conversion of toluene.High-performance photocatalysts not only widely absorb sunlight,but also have abundant active sites and generation of free radicals,which can promote the chemical bonds cleavage of toluene,thus greatly increasing the yield of higher-valued products.In addition,the type of photocatalyst and the modification strategy would influence the selectivity of toluene photo-conversion.Therefore,it makes sense that this review presents the reaction mechanism and the influence of reaction factors for the(mainly)photo-oxidation of toluene,a thorough analysis and prediction of the reaction mechanism by theoretical calculations,and the toluene oxidation by different photocatalysts(in particular halogen-containing perovskite materials)to yield specific products,as well as photocatalysts’modifications.Finally,the challenges and prospects for designing efficient photocatalysts and optimizing the toluene oxidation reaction process are summarized.展开更多
Na_(3)V_(2)(PO_(4))_(3)(NVP)has garnered great attentions as a prospective cathode material for sodium-ion batteries(SIBs)by virtue of its decent theoretical capacity,superior ion conductivity and high structural stab...Na_(3)V_(2)(PO_(4))_(3)(NVP)has garnered great attentions as a prospective cathode material for sodium-ion batteries(SIBs)by virtue of its decent theoretical capacity,superior ion conductivity and high structural stability.However,the inherently poor electronic conductivity and sluggish sodium-ion diffusion kinetics of NVP material give rise to inferior rate performance and unsatisfactory energy density,which strictly confine its further application in SIBs.Thus,it is of significance to boost the sodium storage performance of NVP cathode material.Up to now,many methods have been developed to optimize the electrochemical performance of NVP cathode material.In this review,the latest advances in optimization strategies for improving the electrochemical performance of NVP cathode material are well summarized and discussed,including carbon coating or modification,foreign-ion doping or substitution and nanostructure and morphology design.The foreign-ion doping or substitution is highlighted,involving Na,V,and PO_(4)^(3−)sites,which include single-site doping,multiple-site doping,single-ion doping,multiple-ion doping and so on.Furthermore,the challenges and prospects of high-performance NVP cathode material are also put forward.It is believed that this review can provide a useful reference for designing and developing high-performance NVP cathode material toward the large-scale application in SIBs.展开更多
Dynamic wake field information is vital for the optimized design and control of wind farms.Combined with sparse measurement data from light detection and ranging(LiDAR),the physics-informed neural network(PINN)framewo...Dynamic wake field information is vital for the optimized design and control of wind farms.Combined with sparse measurement data from light detection and ranging(LiDAR),the physics-informed neural network(PINN)frameworks have recently been employed for forecasting freestream wind and wake fields.However,these PINN frameworks face challenges of low prediction accuracy and long training times.Therefore,this paper constructed a PINN framework for dynamic wake field prediction by integrating two accuracy improvement strategies and a step-by-step training time saving strategy.The results showed that the different performance improvement routes significantly improved the overall performance of the PINN.The accuracy and efficiency of the PINN with spatiotemporal improvement strategies were validated via LiDAR-measured data from a wind farm in Shandong province,China.This paper sheds light on load reduction,efficiency improvement,intelligent operation and maintenance of wind farms.展开更多
文摘The actual circumstances of daily life are crucial for the purchasing and pricing strategies of supermarkets.Developing strategies based on these circumstances can assist businesses in ensuring profits and fostering win-win cooperation.This paper explores methods to maximize profit through purchasing and sales strategies.Initially,the relevant data for various categories of vegetables is integrated.Through histograms,their sales patterns are directly understood,highlighting the most popular vegetables.Upon analyzing each vegetable category,it becomes evident that their sales data do not conform to normal distributions.Therefore,Spearman correlation coefficients are calculated,revealing strong correlations between certain categories,such as aquatic roots and edible fungi.A line chart depicting the top ten selling vegetables indicates a noticeable periodicity.Traditional fitting methods struggle to adequately model the sales of each vegetable category and their relationship with cost-plus pricing.To address this,additional factors such as holidays,weeks,and months are incorporated using techniques like random forest regression.This approach yields cost-plus pricing dependence curves that better capture the relationship,while effectively managing noise.Regarding sales volume prediction,the original data displays significant volatility,necessitating the handling of outliers using the threshold method.For missing data,linear interpolation is employed to mitigate the impact of continuous missing values on prediction accuracy.Subsequently,Adam-optimized long short-term memory(LSTM)networks are utilized to forecast incoming quantities for the next seven days.By extrapolating from normal sales volume,market capacity is estimated,allowing for additional sales through discount strategies.This framework has the potential to increase original income by 1.1 times.
文摘Clear aligner treatment is a novel technique in current orthodontic practice.Distinct from traditional fixed orthodontic appliances,clear aligners have different material features and biomechanical characteristics and treatment efficiencies,presenting new clinical challenges.Therefore,a comprehensive and systematic description of the key clinical aspects of clear aligner treatment is essential to enhance treatment efficacy and facilitate the advancement and wide adoption of this new technique.This expert consensus discusses case selection and grading of treatment difficulty,principle of clear aligner therapy,clinical procedures and potential complications,which are crucial to the clinical success of clear aligner treatment.
基金supported by the Natural Science Foundation of Hebei Province(No.E2022208046)National Science Foundation of China(No.52004080)+2 种基金Key project of National Natural Science Foundation of China(No.U20A20130)Key research and development project of Hebei Province(No.22373704D)2023 Central Government Guide Local Science and Technology Development Fund Project(No.236Z1812 G)。
文摘Urbanization and industrialization have escalated water pollution,threatening ecosystems and human health.Water pollution not only degrades water quality but also poses long-term risks to human health through the food chain.The development of efficient wastewater detection and treatment methods is essential for mitigating this environmental hazard.Carbon dots(CDs),as emerging carbon-based nanomaterials,exhibit properties such as biocompatibility,photoluminescence(PL),water solubility,and strong adsorption,positioning them as promising candidates for environmental monitoring and management.Particularly in wastewater treatment,their optical and electron transfer properties make them ideal for pollutant detection and removal.Despite their potential,comprehensive reviews on CDs'role in wastewater treatment are scarce,often lacking detailed insights into their synthesis,PL mechanisms,and practical applications.This review systematically addresses the synthesis,PL mechanisms,and wastewater treatment applications of CDs,aiming to bridge existing research gaps.It begins with an overview of CDs structure and classification,essential for grasping their properties and uses.The paper then explores the pivotal PL mechanisms of CDs,crucial for their sensing capabilities.Next,comprehensive synthesis strategies are presented,encompassing both top-down and bottom-up strategies such as arc discharge,chemical oxidation,and hydrothermal/solvothermal synthesis.The diversity of these methods highlights the potential for tailored CDs production to suit specific environmental applications.Furthermore,the review systematically discusses the applications of CDs in wastewater treatment,including sensing,inorganic removal,and organic degradation.Finally,it delves into the research prospects and challenges of CDs,proposing future directions to enhance their role in wastewater treatment.
基金supported by the National Natural Science Foundation of China,82471345(to LC)the Key Research and Development Program for Social Development by the Jiangsu Provincial Department of Science and Technology.No.BE2022668(to LC).
文摘Ischemic stroke is a major cause of neurological deficits and high disability rate.As the primary immune cells of the central nervous system,microglia play dual roles in neuroinflammation and tissue repair following a stroke.Their dynamic activation and polarization states are key factors that influence the disease process and treatment outcomes.This review article investigates the role of microglia in ischemic stroke and explores potential intervention strategies.Microglia exhibit a dynamic functional state,transitioning between pro-inflammatory(M1)and anti-inflammatory(M2)phenotypes.This duality is crucial in ischemic stroke,as it maintains a balance between neuroinflammation and tissue repair.Activated microglia contribute to neuroinflammation through cytokine release and disruption of the blood-brain barrier,while simultaneously promoting tissue repair through anti-inflammatory responses and regeneration.Key pathways influencing microglial activation include Toll-like receptor 4/nuclear factor kappa B,mitogen-activated protein kinases,Janus kinase/signal transducer and activator of transcription,and phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathways.These pathways are targets for various experimental therapies aimed at promoting M2 polarization and mitigating damage.Potential therapeutic agents include natural compounds found in drugs such as minocycline,as well as traditional Chinese medicines.Drugs that target these regulatory mechanisms,such as small molecule inhibitors and components of traditional Chinese medicines,along with emerging technologies such as single-cell RNA sequencing and spatial transcriptomics,offer new therapeutic strategies and clinical translational potential for ischemic stroke.
基金fully appreciate financial support from NingXia Natural Science Foundation for Outstanding Young Scholar(No.2024AAC04002)CAS“Light of West China”Program,National Natural Science Foundation of China(Key Program,No.12232013)Natural Science Foundation of Ningxia(Key Program,No.2022AAC2003)。
文摘Wire-arc directed energy deposition(wire-arc DED)enables the fabrication of large-scale metal components with rapid manufacturing ability and diverse material selection,making it a compelling technology in industries and defenses.However,challenges in both macroscale and microscale defects still limit printed component widespread applications.Recent advances in automatic and intelligent technologies have brought a range of quality controllable strategies to the forefront.This review covers these new strategies for the printing component,including path planning,process monitoring,auxiliary processes,and post processing,while discussing the expectation for structure and quality improvement.In addition,the work brings new areas of intelligent wire-arc DED development,including advances in digital twin,visualization,and human-processing interaction to promote its performance.It is anticipated that a focus on intelligent system will be key to smart and high-quality manufacturing for future wire-arc DED.
文摘This study aims to explore the characteristics of novice teachers’inappropriate behaviors in classroom teaching and their intervention strategies.With the continuous improvement of education quality,novice teachers face increasing challenges in teaching practice.Their inappropriate behaviors not only affect the classroom atmosphere but may also negatively impact students’learning outcomes.Therefore,researching the characteristics of novice teachers’inappropriate behaviors and their intervention strategies holds significant scientific and social value.This study employs a combination of quantitative and qualitative methods to analyze the behavioral patterns of novice teachers in classroom teaching and proposes corresponding intervention strategies.The results indicate that novice teachers’inappropriate behaviors mainly manifest as poor classroom management,monotonous teaching methods,and insufficient interaction with students.Based on these findings,the study proposes a series of effective intervention strategies,including enhancing teacher training,optimizing teaching design,and promoting positive interactions between teachers and students.The conclusions of the study not only provide practical guidance for educational practice but also point out directions for future research,emphasizing the crucial role of teacher professional development in improving teaching quality.
基金financially supported by the National Key Research and Development Program of China(2023YFC3503902)the National Natural Science Foundation of China(82430108,82293681(82293680),and 82321004)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(2022B1515120015 and 2024A1515030103)the Guangdong Major Project of Basic and Applied Basic Research(2023B0303000026)the Science and Technology Projects in Guangzhou(202102070001)。
文摘Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug discovery but also inspire innovative strategies in drug development.The biomimetic synthesis of natural products employs principles from biomimicry,applying inspiration from biogenetic processes to design synthetic strategies that mimic biosynthetic processes.Biomimetic synthesis is a highly efficient approach in synthetic chemistry,as it addresses critical challenges in the synthesis of structurally complex natural products with significant biological and medicinal importance.It has gained widespread attention from researchers in chemistry,biology,pharmacy,and related fields,underscoring its interdisciplinary impact.In this perspective,we present recent advances and challenges in the biomimetic synthesis of natural products,along with the significance and prospects of this field,highlighting the transformative potential of biomimetic synthesis strategies for both chemical and biosynthetic approaches to natural product synthesis in the pursuit of novel therapeutic agents.
基金the support from the National Natural Science Foun-dation of China(Grant No.U21A20311)the Distinguished Scientist Fellowship Program(DSFP)at King Saud University,Riyadh,Saudi Arabia.
文摘The growing need for higher energy density in rechargeable batteries necessitates the exploration of cathode materials with enhanced specific energy for lithium-ion batteries.Due to their exceptional cost-effectiveness and specific capacity,lithium-rich manganese-based cathode materials(LRMs)obtain in-creasing attention in the pursuit of enhancing energy density and reducing costs.The implementation has faced obstacles in various applications due to substantial capacity and voltage degradation,insufficient safety performance,and restricted rate capability during cycling.These issues arise from the migration of transition metal,the release of oxygen,and structural transformation.In this review,we provide an integrated survey of the structure,lithium storage mechanism,challenges,and origins of LRMs,as well as recent advancements in various coating strategies.Particularly,the significance of optimizing the design of the cathode electrolyte interphase was emphasized to enhance electrode performance.Furthermore,future perspective was also addressed alongside in-situ measurements,advanced synthesis techniques,and the application of machine learning to overcome encountered challenges in LRMs.
基金supported by the National Natural Science Foun-dation of China(52325001,52170009,and 52400114)the National Key Research and Development Program of China(2021YFC3200700 and 2021YFC3200702)+1 种基金the Program of Shanghai Academic Research Leader,China(21XD1424000)the Fundamental Research Funds for the Central Universities.
文摘Climate change is accelerating globally,raising significant concerns regarding the environmental risks associated with combined sewer overflows(CSOs).These rainfall events lead to the excessive discharge of multiple pollutants into natural waters.However,greenhouse gas(GHG)emissions from CSOs,which are crucial for carbon neutrality in urban water systems,remain fragmented.Using the life-cycle assess-ment method expansion approach,this study breaks down the formation and discharge processes of CSOs and uncovers the underlying mechanisms driving GHG emissions during each period.Given the complex-ity and uncertainty in the spatial distribution of GHG emissions from CSOs,the development of standard monitoring and estimation methods is vital.This study identifies the factors influencing GHG emissions within the urban drainage system(UDS)and defines the interactive GHG emission boundaries and accounting framework related to CSOs.This framework is expanded to consider the hybrid nature of urban engineering and hydraulic interactions during the CSO events.Advanced modeling technologies have emerged as essential tools for predicting and managing GHG emissions from CSOs.This review pro-motes comprehensive data-driven methods for predicting GHG emissions from CSOs,fully considering the inherent heterogeneity of CSOs and the impact of multi-source contaminants discharged into aquatic environments.It emphasizes refining emission boundary definitions,novel accounting practices adapting data-driven methods,and comprehensive management strategies in line with the move toward carbon neutrality in the UDS.It advocates the adoption of solutions including advanced technologies and artifi-cial intelligent methods to mitigate CSO-related GHG emissions,stressing the significance of integrating low-carbon solutions and a comprehensive data-driven management framework in future research directions.
文摘Pitch is a complex mixture of polycyclic aromatic hydrocarbons and their non-metal derivatives that has a high carbon content.Using pitch as a precursor for carbon materials in alkali metal ion(Li^(+)/Na^(+)/K^(+))batteries has become of great interest.However,its direct pyrolysis often leads to microstructures with a high orientation and small interlayer spacing due to uncontrolled liquid-phase carbonization,resulting in subpar electrochemical performance.It is therefore important to control the microstructures of pitch-derived carbon materials in order to improve their electrochemical properties.We evaluate the latest progress in the development of these materials using various microstructural engineering approaches,highlighting their use in metal-ion batteries and supercapacitors.The advantages and limitations of pitch molecules and their carbon derivatives are outlined,together with strategies for their modification in order to improve their properties for specific applications.Future research possibilities for structure optimization,scalable production,and waste pitch recycling are also considered.
基金supported by the National Natural Science Foundation of China(Grant No.11971486)。
文摘We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponential distributions.Whenever the server is available,it admits the retrial customers into service based on a first-come first-served rule.The service rate adjusts in real-time based on the retrial queue length.An iterative algorithm is proposed to numerically solve the personal optimal problem in the fully observable scenario.Furthermore,we investigate the impact of parameters on the social optimal threshold.The effectiveness of the results is illustrated by two examples.
文摘In this paper,based on the structure-behavior coupling paradigm,we propose the concept of deviation of central town to describe the geography-market distance between farmers and the central regional town.Using the survey data from farmers in a poverty-stricken village in Western China,the impact of deviation of central town on farmers'livelihood strategies is analyzed.The results indicate that farmers exhibit spatial heterogeneity in their livelihood strategies.Those with low deviation show a strong inclination towards working in urban areas,while those with high deviation tend to integrate into rural industries.The deviation of central town influences farmers'livelihood strategies through the information effect,which is also affected by the level of rural infrastructure and public services,labor force structure and assistance policies.The obtained results are expected to provide guidance for promoting the integration of farmers into the urban-rural economic cycle based on sustainable livelihoods and connecting poverty alleviation with rural revitalization.
文摘Agriculture has become the backbone of most developing countries in the world, especially Tubah Sub-Division North West region, Cameroon. Following the COVID-19 pandemic and socio-political crisis that hit Cameroon’s economy, there has been a steady increase in food insecurity, which has paved the way for farmers to adopt some sustainable strategies to boost agricultural productivity. Therefore, in trying to find models for survival and the pursuit of growth, farmers adopted some traditional farming methods and the use of local input as a means of sustainability. This study specifically seeks to analyze the effect of sustainability strategies on agricultural productivity in Tubah sub-division North West Region, Cameroon. The data was elicited via a survey questionnaire administered to 202 participating farmers selected from the different farmer organizations in the Tubah sub-division. Using cluster-sampling approach, proximity villages were grouped into four clusters of villages, and stratified sampling was used to select farmers to participate in the study. The objective of the study was achieved using OLS and quantile regression estimation techniques. The result showed evidence that the sustainability strategies implemented by the farmers decreased agricultural productivity in the 25th quantile, and at the 50th and 75th quantile, agricultural productivity still declined. This decline is because of unsustainable agricultural strategies like the use of slash and burn, the use of chemical fertilizers, inadequate capital, low level of education, inadequate farming experience, inadequate income, inadequate farm size, and the type of technology used for farming. Based on the findings, this study recommends that the government should organize training programs and seminars, subsidize farm inputs, grant agricultural loans to farmers, and initiate and support mechanized agriculture to boost agricultural productivity.
基金the support from Base for Interdisciplinary Innovative Talent Training,Shanghai Jiao Tong UniversityYouth Science and Technology Innovation Studio of Shanghai Jiao Tong University School of Medicine。
文摘Neural injuries can cause considerable functional impairments,and both central and peripheral nervous systems have limited regenerative capacity.The existing conventional pharmacological treatments in clinical practice show poor targeting,rapid drug clearance from the circulatory system,and low therapeutic efficiency.Therefore,in this review,we have first described the mechanisms underlying nerve regeneration,characterized the biomaterials used for drug delivery to facilitate nerve regeneration,and highlighted the functionalization strategies used for such drug-delivery systems.These systems mainly use natural and synthetic polymers,inorganic materials,and hybrid systems with advanced drug-delivery abilities,including nanoparticles,hydrogels,and scaffoldbased systems.Then,we focused on comparing the types of drug-delivery systems for neural regeneration as well as the mechanisms and challenges associated with targeted delivery of drugs to facilitate neural regeneration.Finally,we have summarized the clinical application research and limitations of targeted delivery of these drugs.These biomaterials and drug-delivery systems can provide mechanical support,sustained release of bioactive molecules,and enhanced intercellular contact,ultimately reducing cell apoptosis and enhancing functional recovery.Nevertheless,immune reactions,degradation regulation,and clinical translations remain major unresolved challenges.Future studies should focus on optimizing biomaterial properties,refining delivery precision,and overcoming translational barriers to advance these technologies toward clinical applications.
基金Tourism College of Zhejiang Fund provided financial support for this research(Project Number:2023CGYB05).
文摘Background:The academic community is increasingly interested in understanding the mechanisms through which gratitude influences coping strategies.In addition,the role of gratitude in fostering long-term resilience and mental health outcomes has garnered significant attention.This study explores the mechanisms through which gratitude affects problem-focused coping strategies and emotion-focused coping strategies by constructing models involving gratitude,perceived social support,self-esteem,and problem-focused coping strategies,as well as models involving gratitude,perceived social support,self-esteem,and emotion-focused coping strategies.Methods:A longitudinal survey was conducted on 1666 Chinese university students using highly reliable and valid scales,including the Gratitude Scale,Perceived Social Support Scale,Self-Esteem Scale,and Brief Coping Strategies Scale.To examine whether perceived social support and self-esteem play a significant indirect role in the relationship between gratitude and problem-focused coping strategies,as well as between gratitude and emotion-focused coping strategies.Differences in variables based on demographic variables:We used one-way ANOVA to test the differences in gratitude,perceived social support,self-esteem,problem-focused coping strategies,and emotion-focused coping strategies among students of different grades and ages.Additionally,independent samples t-tests were used to examine the differences between students of different genders and household registrations.Results:The study found that(1)Gratitude significantly positively predicted perceived social support(β=0.661,p<0.001),self-esteem(β=0.234,p<0.001),and problemfocused coping strategies(β=0.130,p<0.001);(2)Perceived social support significantly positively predicted self-esteem(β=0.440,p<0.001;β=0.439,p<0.001),problem-focused coping strategies(β=0.443,p<0.001),and emotion-focused coping strategies(β=0.279,p<0.001);(3)Self-esteem significantly positively predicted problem-focused coping strategies(β=0.172,p<0.001)and significantly negatively predicted emotion-focused coping strategies(β=−0.205,p<0.001);(4)Gratitude can influence problem-focused coping strategies through the dual indirect effect of two mediating variables.After the inclusion of the mediating variables,the effect of problem-focused coping strategies in the indirect model was further strengthened.(5)Gratitude can influence emotion-focused coping strategies through a completely indirect effect on perceived social support and self-esteem.After inserting the mediating variables,the effect of emotionfocused coping strategies in the mediating model is enhanced.Conclusion:Gratitude can directly and positively predict problem-focused coping strategies,and it can also positively predict problem-focused coping strategies through the dual indirect effect of two mediating variables.Gratitude does not significantly predict emotion-focused coping strategies directly,but it can influence emotion-focused coping strategies via a double indirect pathway.
文摘This article focuses on the challenges of rural economic development under the strategy of rural revitalization,and deeply analyzes the current situation of rural economic development.Research has found that although the rural revitalization strategy has achieved significant results in improving residents’quality of life,promoting agricultural modernization,it still faces challenges such as severe loss of human resources,insufficient agricultural technological innovation,and backward infrastructure construction.In response to these challenges,this paper proposes optimization strategies from three aspects:strengthening rural education and talent team construction,promoting agricultural technology innovation and achievement transformation,and increasing investment in rural infrastructure construction.
文摘The interplay of academic atmosphere,learning motivation,and strategies inherently influences English learning.Effective vocabulary acquisition strategies significantly influence the achievements of English acquisition.Vocabulary mastery,a cornerstone of middle school English education,raises a critical question:How can vocabulary strategies optimize students’memory,understanding,and vocabulary application?This article elaborates on the importance and characteristics of vocabulary learning in Chinese junior high schools,analyzes definitions and theories of learning strategies,and proposes specific vocabulary approaches tailored to junior high school students in rural-urban fringe areas.
基金supported by the Natural Sciences and Engineering Research Council of Canada-Discovery Grant(Canada).
文摘Toluene is widely used as a raw material for many chemical products/pharmaceutical intermediates and as a solvent in many chemical and manufacturing industries.The conversion of toluene into higher value chemicals(benzyl alcohol,benzaldehyde,and benzoic acid,etc.)using sunlight is a very promising means.To achieve the full conversion and utilization of toluene,it is necessary to construct photocatalysts with high conversion and selectivity while synergistically optimizing the optimal reaction environment to significantly affect the photo-conversion of toluene.High-performance photocatalysts not only widely absorb sunlight,but also have abundant active sites and generation of free radicals,which can promote the chemical bonds cleavage of toluene,thus greatly increasing the yield of higher-valued products.In addition,the type of photocatalyst and the modification strategy would influence the selectivity of toluene photo-conversion.Therefore,it makes sense that this review presents the reaction mechanism and the influence of reaction factors for the(mainly)photo-oxidation of toluene,a thorough analysis and prediction of the reaction mechanism by theoretical calculations,and the toluene oxidation by different photocatalysts(in particular halogen-containing perovskite materials)to yield specific products,as well as photocatalysts’modifications.Finally,the challenges and prospects for designing efficient photocatalysts and optimizing the toluene oxidation reaction process are summarized.
基金partly supported by the National Natural Science Foundation of China(Grant No.52272225).
文摘Na_(3)V_(2)(PO_(4))_(3)(NVP)has garnered great attentions as a prospective cathode material for sodium-ion batteries(SIBs)by virtue of its decent theoretical capacity,superior ion conductivity and high structural stability.However,the inherently poor electronic conductivity and sluggish sodium-ion diffusion kinetics of NVP material give rise to inferior rate performance and unsatisfactory energy density,which strictly confine its further application in SIBs.Thus,it is of significance to boost the sodium storage performance of NVP cathode material.Up to now,many methods have been developed to optimize the electrochemical performance of NVP cathode material.In this review,the latest advances in optimization strategies for improving the electrochemical performance of NVP cathode material are well summarized and discussed,including carbon coating or modification,foreign-ion doping or substitution and nanostructure and morphology design.The foreign-ion doping or substitution is highlighted,involving Na,V,and PO_(4)^(3−)sites,which include single-site doping,multiple-site doping,single-ion doping,multiple-ion doping and so on.Furthermore,the challenges and prospects of high-performance NVP cathode material are also put forward.It is believed that this review can provide a useful reference for designing and developing high-performance NVP cathode material toward the large-scale application in SIBs.
基金supported by the National Natural Science Foundation of China(Grant Nos.12072105,11932006,and 52308498)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20220976).
文摘Dynamic wake field information is vital for the optimized design and control of wind farms.Combined with sparse measurement data from light detection and ranging(LiDAR),the physics-informed neural network(PINN)frameworks have recently been employed for forecasting freestream wind and wake fields.However,these PINN frameworks face challenges of low prediction accuracy and long training times.Therefore,this paper constructed a PINN framework for dynamic wake field prediction by integrating two accuracy improvement strategies and a step-by-step training time saving strategy.The results showed that the different performance improvement routes significantly improved the overall performance of the PINN.The accuracy and efficiency of the PINN with spatiotemporal improvement strategies were validated via LiDAR-measured data from a wind farm in Shandong province,China.This paper sheds light on load reduction,efficiency improvement,intelligent operation and maintenance of wind farms.
