Protein arginine methyltransferase 7(PRMT7)is closely related to the formation of lung cancer,breast cancer and other malignant tumors,and it may be a potential target gene for malignant tumor therapy.Dishevelleds(DVL...Protein arginine methyltransferase 7(PRMT7)is closely related to the formation of lung cancer,breast cancer and other malignant tumors,and it may be a potential target gene for malignant tumor therapy.Dishevelleds(DVLs)are key factors involved in cell proliferation,invasion and metastasis.Among the dishevelleds,the dishevelled segment polarity protein 3(DVL3)is a key protein in the Wnt signaling pathway,and its abnormal expression plays an important role in the occurrence and development of malignant tumors.This paper reviewed the advances in research of PRMT7 and DVL3 in gastric cancer.展开更多
基金Supported by Chengde Medical University-National Natural Science Foundation of China Project Cultivation Fund (202114)Chengde Medical UniversitySchool-level Key Project Fund (201711)+1 种基金Key Discipline Construction Project of Hebei Province [Ji Jiao Gao (2013) No. 4:Pathology and Pathophysiology]Master Candidate Innovation Ability Training Funding Project of Hebei Province (CXZZSS2022141)
文摘Protein arginine methyltransferase 7(PRMT7)is closely related to the formation of lung cancer,breast cancer and other malignant tumors,and it may be a potential target gene for malignant tumor therapy.Dishevelleds(DVLs)are key factors involved in cell proliferation,invasion and metastasis.Among the dishevelleds,the dishevelled segment polarity protein 3(DVL3)is a key protein in the Wnt signaling pathway,and its abnormal expression plays an important role in the occurrence and development of malignant tumors.This paper reviewed the advances in research of PRMT7 and DVL3 in gastric cancer.
