Altogether 27716 cystic hydatid cases and 445 alveolar hydatid cases slinically diagnosed and surgically treated in China were retrospectively studied.
Large populations with multi-modal biomedical phenotypes are crucial for investigating the potential causes of human diseases.In particular,large population-based imaging studies can provide detailed imaging-derived p...Large populations with multi-modal biomedical phenotypes are crucial for investigating the potential causes of human diseases.In particular,large population-based imaging studies can provide detailed imaging-derived phenotypes(IDPs)to quantitatively describe the anatomical structure and function for assessing their associations with genetics,life-style factors and disease outcomes.However,it is not a trivial task to initiate a large population-based imaging study,considering the challenges of logistics,cost,standardisation of the image acquisition protocol,robust image analysis pipelines for IDP extraction and quality control etc.Published in Phenomics,Wang et al.describe the brain image acquisition and phenotyping protocol for the China Phenobank Project(CHPP)(Wang et al.2023),an effort to assess and understand the current health status of a Chinese population,as well as to investigate the causes and progression of common diseases in China.展开更多
文摘Altogether 27716 cystic hydatid cases and 445 alveolar hydatid cases slinically diagnosed and surgically treated in China were retrospectively studied.
文摘Large populations with multi-modal biomedical phenotypes are crucial for investigating the potential causes of human diseases.In particular,large population-based imaging studies can provide detailed imaging-derived phenotypes(IDPs)to quantitatively describe the anatomical structure and function for assessing their associations with genetics,life-style factors and disease outcomes.However,it is not a trivial task to initiate a large population-based imaging study,considering the challenges of logistics,cost,standardisation of the image acquisition protocol,robust image analysis pipelines for IDP extraction and quality control etc.Published in Phenomics,Wang et al.describe the brain image acquisition and phenotyping protocol for the China Phenobank Project(CHPP)(Wang et al.2023),an effort to assess and understand the current health status of a Chinese population,as well as to investigate the causes and progression of common diseases in China.