Modified NaY zeolites have been widely studied and the modification metal element is normally single, while few researches have been conducted on NaY zeolites modified by two kinds of metals. In our study, a series of...Modified NaY zeolites have been widely studied and the modification metal element is normally single, while few researches have been conducted on NaY zeolites modified by two kinds of metals. In our study, a series of La3+ and Ba2+ modified NaY zeolites were synthesized through different impregnation procedures. Lactic acid dehydration to acrylic acid was selected as a probe reaction to test the catalytic performance of these zeolites synthesized. The effects of synthesis details on their pore structures an...展开更多
Four types of seismic design details were tested using 11 transfer column specimens and one comparison specimen of RC under low cyclic reversed loading. Test results show that diagonal cracks control the failure patte...Four types of seismic design details were tested using 11 transfer column specimens and one comparison specimen of RC under low cyclic reversed loading. Test results show that diagonal cracks control the failure pattern and damage occurs mainly in the RC section with weak shear capacity in the transfer columns. There is a large difference in the bearing capacity and ductility of the transfer columns according to the test results, which indicates that the strengthening effect of diverse structural measures is quite different. The section ratio of I-section-encased steel and the axial compression ratio also have a great influence on the bearing capacity and ductility. Although the bearing capacity of transfer columns with additional longitudinal bars and additional X bars is relatively large, they have poor deformation capacity. Setting more stirrups along the columns is the best structural measure to enhance the seismic performance. The studs on the I-sectionencased steel by welding can help to complete the stress transfer between the steel and concrete, and avoid performance degradation of the two materials due to bonding failure.展开更多
An original reinforced concrete(RC) column and four strengthened specimens, two with RC jackets and two with wing walls, were tested in this study. The original column specimen was designed to comply with older(pre-19...An original reinforced concrete(RC) column and four strengthened specimens, two with RC jackets and two with wing walls, were tested in this study. The original column specimen was designed to comply with older(pre-1999) design standards so that the usual detailing defi ciencies in existing school buildings in Taiwan could be simulated. Two different structural details were chosen to fabricate the full-scale specimens for each retrofi tting technique. The study confi rmed that either RC jacketing or the installation of wing walls with two different structural details can effectively improve the stiffness and strength of an existing column. RC jacketing shows a better improvement in energy dissipation and ductility when compared to the columns with wing walls installed. This is because the two RC jacketed columns experienced a fl exural failure, while a shear failure was found in the two columns with the wing walls installed, and thus led to a drastic decrease of the maximum lateral strengths and ductility. Since many factors may affect the installation of a post-installed anchor, it is better to use standard hooks to replace post-installed anchors in some specifi c points when using RC jacketing or installing wing walls.展开更多
To study the fatigue performance of welded details in the orthotropic steel decks,the steel box girder for Taizhou Yangtze River Bridge is taken as the research object.Based on the field monitoring data obtained from ...To study the fatigue performance of welded details in the orthotropic steel decks,the steel box girder for Taizhou Yangtze River Bridge is taken as the research object.Based on the field monitoring data obtained from the load test,the stress response test of the orthotropic steel box girder under wheel loads is performed and the correctness of the vehicle test data obtained from the field monitoring data also have been verified by the numerical results of the finite element model.Based on the Miner linear cumulative damage theory,the S-N curve of the Eurocode3 specification is referenced,and the fatigue life calculation formula of the welded details is determined according to the actual structural features.The fatigue life evaluation of the four typical welded details is obtained.The results indicate that:The load test data is compared and verified by the numerical result of finite element model.The local effect of stress distribution is remarkable.The stress measurement points on the four typical welded details are mainly based on low amplitude stress cycles.Most of the stress ranges are 2-10 MPa,among which the stress range of the welded details at the U-rib butt joint is larger.The fatigue life of welded details in the 14 mm thick top plate is smaller than that of the 16 mm thick top plate corresponding to the fatigue life of the welded details.The rib-to-rib butt welded joints and the openings of the diaphragms were prone to fatigue failure.Among them,the welding details of the 14 mm thick U-rib butt joints first appeared fatigue failure.The arrangement of the diaphragm can effectively increase the fatigue life of the top-U rib weld and improve the fatigue performance at this detail.展开更多
In order to study the fatigue properties of rib-to-deck welded connection and rib-to-rib welded connection in orthotropic steel bridge decks,a multi-scale finite element model was set up to analyze the stress distribu...In order to study the fatigue properties of rib-to-deck welded connection and rib-to-rib welded connection in orthotropic steel bridge decks,a multi-scale finite element model was set up to analyze the stress distribution characteristics and the load test was conducted on the Taizhou Yangtze River Bridge.Comparing the vehicle test results with the muli-scale finite element model results to verify the accuracy of the finite element simulation for the stress response of two welded details.The results indicated that The stress at the rib-to-deck welded connection and the rib-to-rib welded connection are the bending stress and the membrane stress,respectively;the stress response of the two welded connection has strong local characteristics;the lateral stress influence line of the two welded connection is relatively short and the length of the lateral stress influence line is greatly affected by the longitudinal ribs;increasing the thickness of the roof and longitudinal ribs can reduce the stress response and improve the stress performance of the heavy lanes.For the two welded details,the fatigue damage increment of the ordinary lane is greater than the heavy lane.The thickened roof and longitudinal ribs at the position of the heavy lane still cannot balance the fatigue damage caused by the heavy truck.Therefore,it is necessary to strictly control the fatigue effect of overloaded vehicles on steel box girders.展开更多
Objective: This paper aims to explore the impact of optimizing details in the operating room on the level of knowledge, attitude, and practice of hospital infection prevention and control by surgeons, as well as the e...Objective: This paper aims to explore the impact of optimizing details in the operating room on the level of knowledge, attitude, and practice of hospital infection prevention and control by surgeons, as well as the effectiveness of infection control. Methods: From January 2022 to June 2023, a total of 120 patients were screened and randomly divided into a control group (routine care and hospital infection management) and a study group (optimizing details in the operating room). Results: Significant differences were found between the two groups in the data of surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, infection rates, and nursing satisfaction, with the study group showing better results (P Conclusion: The use of optimizing details in the operating room among surgeons can effectively improve surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, reduce infection occurrence, and is worth promoting.展开更多
Advances in imaging have led to the development of several new types of microscopes such as serial block face scanning electron microscopy (SBF-SEM),lightsheet microscopy,as well as X-ray micro-computed tomography (mi...Advances in imaging have led to the development of several new types of microscopes such as serial block face scanning electron microscopy (SBF-SEM),lightsheet microscopy,as well as X-ray micro-computed tomography (micro-CT),which enables the study of samples in fundamentally different ways.展开更多
2016 Amazing China - The Most Attractive Chinese Cities for Foreigners election were released. 1701 foreign experts participated in a survey along with the election. The survey is mainly about expats’ working and liv...2016 Amazing China - The Most Attractive Chinese Cities for Foreigners election were released. 1701 foreign experts participated in a survey along with the election. The survey is mainly about expats’ working and living environment in china . Why they come to china? What factors affect their choice in cities? Are they satisfied with their salary? We will disclose the details for you.展开更多
Objective: to study and analyze the role of details combined with home care in intensive care. Methods: the critically ill patients admitted to our hospital in recent 1 year (August 2020-August 2021) were selected for...Objective: to study and analyze the role of details combined with home care in intensive care. Methods: the critically ill patients admitted to our hospital in recent 1 year (August 2020-August 2021) were selected for nursing combined with the details of home care. Results: after effective nursing, the patients bad psychology was obviously relieved, which further promoted the improvement of nursing satisfaction. Conclusion: for critically ill patients, the implementation of detailed nursing combined with family-friendly nursing has a positive effect on improving the prognosis and is worthy of promotion and application.展开更多
At present, the most important part of Chinas infrastructure is the road and bridge project, which has a significant impact on social traffic and has played a positive role in the development of the whole society. How...At present, the most important part of Chinas infrastructure is the road and bridge project, which has a significant impact on social traffic and has played a positive role in the development of the whole society. However, the road and bridge engineering is very complicated, and it is bound to encounter various problems. Relevant personnel must pay attention to the construction technology and improve the construction quality. Specifically, relevant personnel should strictly implement relevant codes and technical standards, strictly follow the construction principles, strengthen the quality monitoring of road and bridge construction, and effectively extend the service life of road and bridge. Before construction, relevant design work must be done first, and then the details of various construction technologies should be optimized. If the construction technology is not properly selected, it will involve many quality problems of road and bridge, and even shorten the service life. Therefore, in the process of road and bridge construction, technicians need to solve the details of existing construction techniques in time to improve traffic safety.展开更多
ECO-88D Double Rope High Speed Dyeing Machine ECO-88D Double Rope High Speed Dyeing Machine is suitable for the processing of light to medium weight fabric made from synthetic ber. Fabric structure suitable for the dy...ECO-88D Double Rope High Speed Dyeing Machine ECO-88D Double Rope High Speed Dyeing Machine is suitable for the processing of light to medium weight fabric made from synthetic ber. Fabric structure suitable for the dyeing process inside the ECO-88D includes woven,展开更多
For accurate and stable haptic rendering, collision detection for interactive haptic applications has to be done by filling in or covering target objects as tightly as possible with bounding volumes （spheres, axis-al...For accurate and stable haptic rendering, collision detection for interactive haptic applications has to be done by filling in or covering target objects as tightly as possible with bounding volumes （spheres, axis-aligned bounding boxes, oriented bounding boxes, or polytopes）. In this paper, we propose a method for creating bounding spheres with respect to the contact levels of details （CLOD）, which can fit objects while maintaining the balance between high speed and precision of collision detection. Our method is composed mainly of two parts： bounding sphere formation and two-level collision detection. To specify further, bounding sphere formation can be divided into two steps： creating spheres and clustering spheres. Two-level collision detection has two stages as well： fast detection of spheres and precise detection in spheres. First, bounding spheres are created for initial fast probing to detect collisions of spheres. Once a collision is probed, a more precise detection is executed by examining the distance between a haptie pointer and each mesh inside the colliding boundaries. To achieve this refmed level of detection, a special data structure of a bounding volume needs to be defined to include all mesh information in the sphere. After performing a number of experiments to examine the usefulness and performance of our method, we have concluded that our algorithm is fast and precise enough for haptic simulations. The high speed detection is achieved through the clustering of spheres, while detection precision is realized by voxel-based direct collision detection. Our method retains its originality through the CLOD by distance-based clustering.展开更多
Osteoblasts are essential in the maintenance of human bone homeostasis.1 The abnormal formation and impaired differentiation ability of osteoblasts are pivotal factors leading to bone-related diseases,suggesting that ...Osteoblasts are essential in the maintenance of human bone homeostasis.1 The abnormal formation and impaired differentiation ability of osteoblasts are pivotal factors leading to bone-related diseases,suggesting that an indepth study of osteoblasts can provide novel treatment strategies for these diseases.2 Human primary osteoblasts are precious experimental models in bone-related research.3 However,the isolation and culture of human primary osteoblasts still have some difficulties and limitations.Here,we refined a method to isolate and culture human primary osteoblasts by taking cancellous bone through a bone tissue sampler and pre-digesting it with pancreatin,which makes the process easier,cheaper,and more efficient.Furthermore,we compared the effects of the subtle changes in isolation and culture methods on the phenotype of human primary osteoblasts and examined the differences in morphology,proliferation,and differentiation between micro-explants cultured osteoblasts(MECOBs)and explants cultured osteoblasts(EC-OBs).展开更多
High-resolution lens-coupled indirect X-ray scintillator imagers are required by many imaging applications.However,the severe weakening of image details prevents its further performance improvement.Through our researc...High-resolution lens-coupled indirect X-ray scintillator imagers are required by many imaging applications.However,the severe weakening of image details prevents its further performance improvement.Through our research,this image degradation is attributed to the broadband loss of the high-spatial-frequency information caused by the high refractive index.A technique known as high-spatial-frequency spectrum enhanced reconstruction is thus proposed to retrieve this information.A two-dimensional high-density array is covered on the scintillator’s exit surface and operates as an encoder based on which high-frequency information can be shifted to the low-frequency region to improve the signal-to-noise ratio.The experimental results show that the middle-high-frequency signal intensities can be increased by an order of magnitude or more,up to^50 times.Therefore,the image details can be effectively enhanced to break through the performance bottleneck of such widely used X-ray imagers for synchrotron radiation facilities or tabletop X-ray tubes.展开更多
Many foreign sinologists often suffer from misconception and confusion about China,its governance,society and culture.The three volumes of Xi Jinping:The Governance of China,published in many languages,address the pre...Many foreign sinologists often suffer from misconception and confusion about China,its governance,society and culture.The three volumes of Xi Jinping:The Governance of China,published in many languages,address the predicament of foreigners wanting to know about China.For me,these books have been the best source to learn about contemporary China,its people,society,foreign policy and the driving spirit behind the country’s remarkable success.展开更多
As machine learning(ML)continues to advance in the field of materials science,the variation in strategies for the same steps of the ML workflow becomes increasingly significant.These details can have a substantial imp...As machine learning(ML)continues to advance in the field of materials science,the variation in strategies for the same steps of the ML workflow becomes increasingly significant.These details can have a substantial impact on results,yet they have not received the deserved attention.This review aims to explore the various strategies available for each detail within the general workflow of materials ML.Firstly,the general workflow of materials ML will be introduced to help readers gain an understanding of potential details.Subsequently,different strategies of details within each step of the workflow will be presented through state-of-the-art case studies.The potential outcomes associated with choosing different strategies to details will be explored.Following this,suitable strategies for details will be recommended based on distinct application scenarios.Finally,directions for the future development of materials ML concerning details will be proposed.Through these discussions,we aspire to offer a comprehensive understanding of the nuances in details within materials ML.This will serve as valuable reference and guidance for researchers in both materials science and ML.展开更多
Interview time: August 16, 2006 Figure in focus: Wang Jun, Director of Sales & Marketing of Plaza Hotel Wang Jun, Director of Sales and Marketing at the Plaza Hotel, has worked as a senior officer for top-ranking ...Interview time: August 16, 2006 Figure in focus: Wang Jun, Director of Sales & Marketing of Plaza Hotel Wang Jun, Director of Sales and Marketing at the Plaza Hotel, has worked as a senior officer for top-ranking hotels over the past 15 years. And now, he is pursuing higher goals in his new career at the Plaza Hotel. During the interview, his kindness and modesty left a deep impression. He is efficient, conscientious and always pleasant to everyone,展开更多
基金Project supported by National Natural Science Foundation of China (20906051)Jiangsu Province Fundamental Research Plan (BK2009478)+1 种基金Hi-Tech Research and Development Program of China (2006AA020101)the Key Discipline Fund of Nanjing University of Technology
文摘Modified NaY zeolites have been widely studied and the modification metal element is normally single, while few researches have been conducted on NaY zeolites modified by two kinds of metals. In our study, a series of La3+ and Ba2+ modified NaY zeolites were synthesized through different impregnation procedures. Lactic acid dehydration to acrylic acid was selected as a probe reaction to test the catalytic performance of these zeolites synthesized. The effects of synthesis details on their pore structures an...
基金Supported by:National Natural Science Foundation of China under Grant No.51208175the Fundamental Research Funds for the Central Universities under Grant Nos.2015B17514 and 2016B20514
文摘Four types of seismic design details were tested using 11 transfer column specimens and one comparison specimen of RC under low cyclic reversed loading. Test results show that diagonal cracks control the failure pattern and damage occurs mainly in the RC section with weak shear capacity in the transfer columns. There is a large difference in the bearing capacity and ductility of the transfer columns according to the test results, which indicates that the strengthening effect of diverse structural measures is quite different. The section ratio of I-section-encased steel and the axial compression ratio also have a great influence on the bearing capacity and ductility. Although the bearing capacity of transfer columns with additional longitudinal bars and additional X bars is relatively large, they have poor deformation capacity. Setting more stirrups along the columns is the best structural measure to enhance the seismic performance. The studs on the I-sectionencased steel by welding can help to complete the stress transfer between the steel and concrete, and avoid performance degradation of the two materials due to bonding failure.
基金the fi nancial support for this study from the Architecture and Building Research Institute,Chinese Taipei,under Grant No.099301070000G1005
文摘An original reinforced concrete(RC) column and four strengthened specimens, two with RC jackets and two with wing walls, were tested in this study. The original column specimen was designed to comply with older(pre-1999) design standards so that the usual detailing defi ciencies in existing school buildings in Taiwan could be simulated. Two different structural details were chosen to fabricate the full-scale specimens for each retrofi tting technique. The study confi rmed that either RC jacketing or the installation of wing walls with two different structural details can effectively improve the stiffness and strength of an existing column. RC jacketing shows a better improvement in energy dissipation and ductility when compared to the columns with wing walls installed. This is because the two RC jacketed columns experienced a fl exural failure, while a shear failure was found in the two columns with the wing walls installed, and thus led to a drastic decrease of the maximum lateral strengths and ductility. Since many factors may affect the installation of a post-installed anchor, it is better to use standard hooks to replace post-installed anchors in some specifi c points when using RC jacketing or installing wing walls.
基金This study was financially supported by the National Natural Science Foundation,China(51778135)the Natural Science Foundation of Jiangsu Province,China(BK20160207)+3 种基金Aeronautical Science Foundation,China(20130969010)the Fundamental Research Funds for the Central Universities and Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(KYCX18_0113KYLX16_0253)the National Key Research and Development Program of China(2017YFC0806001).
文摘To study the fatigue performance of welded details in the orthotropic steel decks,the steel box girder for Taizhou Yangtze River Bridge is taken as the research object.Based on the field monitoring data obtained from the load test,the stress response test of the orthotropic steel box girder under wheel loads is performed and the correctness of the vehicle test data obtained from the field monitoring data also have been verified by the numerical results of the finite element model.Based on the Miner linear cumulative damage theory,the S-N curve of the Eurocode3 specification is referenced,and the fatigue life calculation formula of the welded details is determined according to the actual structural features.The fatigue life evaluation of the four typical welded details is obtained.The results indicate that:The load test data is compared and verified by the numerical result of finite element model.The local effect of stress distribution is remarkable.The stress measurement points on the four typical welded details are mainly based on low amplitude stress cycles.Most of the stress ranges are 2-10 MPa,among which the stress range of the welded details at the U-rib butt joint is larger.The fatigue life of welded details in the 14 mm thick top plate is smaller than that of the 16 mm thick top plate corresponding to the fatigue life of the welded details.The rib-to-rib butt welded joints and the openings of the diaphragms were prone to fatigue failure.Among them,the welding details of the 14 mm thick U-rib butt joints first appeared fatigue failure.The arrangement of the diaphragm can effectively increase the fatigue life of the top-U rib weld and improve the fatigue performance at this detail.
基金This research has been supported by the National Natural Science Foundation of China(Grant No.51778135)the National Key R&D Program Foundation of China(Grant No.2017YFC0806001)+2 种基金the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20160207)Aeronautical Science Foundation of China(Grant No.20130969010)the Fundamental Research Funds for the Central Universities and Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant Nos.KYCX18_0113 and KYLX16_0253).
文摘In order to study the fatigue properties of rib-to-deck welded connection and rib-to-rib welded connection in orthotropic steel bridge decks,a multi-scale finite element model was set up to analyze the stress distribution characteristics and the load test was conducted on the Taizhou Yangtze River Bridge.Comparing the vehicle test results with the muli-scale finite element model results to verify the accuracy of the finite element simulation for the stress response of two welded details.The results indicated that The stress at the rib-to-deck welded connection and the rib-to-rib welded connection are the bending stress and the membrane stress,respectively;the stress response of the two welded connection has strong local characteristics;the lateral stress influence line of the two welded connection is relatively short and the length of the lateral stress influence line is greatly affected by the longitudinal ribs;increasing the thickness of the roof and longitudinal ribs can reduce the stress response and improve the stress performance of the heavy lanes.For the two welded details,the fatigue damage increment of the ordinary lane is greater than the heavy lane.The thickened roof and longitudinal ribs at the position of the heavy lane still cannot balance the fatigue damage caused by the heavy truck.Therefore,it is necessary to strictly control the fatigue effect of overloaded vehicles on steel box girders.
文摘Objective: This paper aims to explore the impact of optimizing details in the operating room on the level of knowledge, attitude, and practice of hospital infection prevention and control by surgeons, as well as the effectiveness of infection control. Methods: From January 2022 to June 2023, a total of 120 patients were screened and randomly divided into a control group (routine care and hospital infection management) and a study group (optimizing details in the operating room). Results: Significant differences were found between the two groups in the data of surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, infection rates, and nursing satisfaction, with the study group showing better results (P Conclusion: The use of optimizing details in the operating room among surgeons can effectively improve surgeons’ level of knowledge, attitude, and practice in hospital infection prevention and control, reduce infection occurrence, and is worth promoting.
基金supported by the Awards to JAR from the UK Macular Society,UKRI Quality Research Strategic Priorities Fund from Public Policy Southampton (New Things Fund) as well as the Gift of Sight Appeal。
文摘Advances in imaging have led to the development of several new types of microscopes such as serial block face scanning electron microscopy (SBF-SEM),lightsheet microscopy,as well as X-ray micro-computed tomography (micro-CT),which enables the study of samples in fundamentally different ways.
文摘2016 Amazing China - The Most Attractive Chinese Cities for Foreigners election were released. 1701 foreign experts participated in a survey along with the election. The survey is mainly about expats’ working and living environment in china . Why they come to china? What factors affect their choice in cities? Are they satisfied with their salary? We will disclose the details for you.
文摘Objective: to study and analyze the role of details combined with home care in intensive care. Methods: the critically ill patients admitted to our hospital in recent 1 year (August 2020-August 2021) were selected for nursing combined with the details of home care. Results: after effective nursing, the patients bad psychology was obviously relieved, which further promoted the improvement of nursing satisfaction. Conclusion: for critically ill patients, the implementation of detailed nursing combined with family-friendly nursing has a positive effect on improving the prognosis and is worthy of promotion and application.
文摘At present, the most important part of Chinas infrastructure is the road and bridge project, which has a significant impact on social traffic and has played a positive role in the development of the whole society. However, the road and bridge engineering is very complicated, and it is bound to encounter various problems. Relevant personnel must pay attention to the construction technology and improve the construction quality. Specifically, relevant personnel should strictly implement relevant codes and technical standards, strictly follow the construction principles, strengthen the quality monitoring of road and bridge construction, and effectively extend the service life of road and bridge. Before construction, relevant design work must be done first, and then the details of various construction technologies should be optimized. If the construction technology is not properly selected, it will involve many quality problems of road and bridge, and even shorten the service life. Therefore, in the process of road and bridge construction, technicians need to solve the details of existing construction techniques in time to improve traffic safety.
文摘ECO-88D Double Rope High Speed Dyeing Machine ECO-88D Double Rope High Speed Dyeing Machine is suitable for the processing of light to medium weight fabric made from synthetic ber. Fabric structure suitable for the dyeing process inside the ECO-88D includes woven,
基金supported by Incheon National University Research,Korea(No.20120238)
文摘For accurate and stable haptic rendering, collision detection for interactive haptic applications has to be done by filling in or covering target objects as tightly as possible with bounding volumes （spheres, axis-aligned bounding boxes, oriented bounding boxes, or polytopes）. In this paper, we propose a method for creating bounding spheres with respect to the contact levels of details （CLOD）, which can fit objects while maintaining the balance between high speed and precision of collision detection. Our method is composed mainly of two parts： bounding sphere formation and two-level collision detection. To specify further, bounding sphere formation can be divided into two steps： creating spheres and clustering spheres. Two-level collision detection has two stages as well： fast detection of spheres and precise detection in spheres. First, bounding spheres are created for initial fast probing to detect collisions of spheres. Once a collision is probed, a more precise detection is executed by examining the distance between a haptie pointer and each mesh inside the colliding boundaries. To achieve this refmed level of detection, a special data structure of a bounding volume needs to be defined to include all mesh information in the sphere. After performing a number of experiments to examine the usefulness and performance of our method, we have concluded that our algorithm is fast and precise enough for haptic simulations. The high speed detection is achieved through the clustering of spheres, while detection precision is realized by voxel-based direct collision detection. Our method retains its originality through the CLOD by distance-based clustering.
基金supported by the National Natural Science Foundation of China(No.82170896,31970569)Science Fund for Distinguished Young Scholars of Shaanxi Province,China(No.2021JC-02)+3 种基金Innovation Capability Support Program of Shaanxi Province,China(No.2022TD-44)China Postdoctoral Science Foundation(No.2021M692582)Natural Science Basic Research Program of Shaanxi Province,China(No.2022JQ-808,2023-YBSF-180)Fundamental Research Funds for the Central Universities(China)(No.xzy012022032).
文摘Osteoblasts are essential in the maintenance of human bone homeostasis.1 The abnormal formation and impaired differentiation ability of osteoblasts are pivotal factors leading to bone-related diseases,suggesting that an indepth study of osteoblasts can provide novel treatment strategies for these diseases.2 Human primary osteoblasts are precious experimental models in bone-related research.3 However,the isolation and culture of human primary osteoblasts still have some difficulties and limitations.Here,we refined a method to isolate and culture human primary osteoblasts by taking cancellous bone through a bone tissue sampler and pre-digesting it with pancreatin,which makes the process easier,cheaper,and more efficient.Furthermore,we compared the effects of the subtle changes in isolation and culture methods on the phenotype of human primary osteoblasts and examined the differences in morphology,proliferation,and differentiation between micro-explants cultured osteoblasts(MECOBs)and explants cultured osteoblasts(EC-OBs).
基金National Key Research and Development Program of China(2017YFA0403400,2016YFA0401302)Science and Technology Commission of Shanghai Municipality(17JC1400802)+1 种基金National Natural Science Foundation of China(11775291)Shanghai Giant Science Center RD Project。
文摘High-resolution lens-coupled indirect X-ray scintillator imagers are required by many imaging applications.However,the severe weakening of image details prevents its further performance improvement.Through our research,this image degradation is attributed to the broadband loss of the high-spatial-frequency information caused by the high refractive index.A technique known as high-spatial-frequency spectrum enhanced reconstruction is thus proposed to retrieve this information.A two-dimensional high-density array is covered on the scintillator’s exit surface and operates as an encoder based on which high-frequency information can be shifted to the low-frequency region to improve the signal-to-noise ratio.The experimental results show that the middle-high-frequency signal intensities can be increased by an order of magnitude or more,up to^50 times.Therefore,the image details can be effectively enhanced to break through the performance bottleneck of such widely used X-ray imagers for synchrotron radiation facilities or tabletop X-ray tubes.
文摘Many foreign sinologists often suffer from misconception and confusion about China,its governance,society and culture.The three volumes of Xi Jinping:The Governance of China,published in many languages,address the predicament of foreigners wanting to know about China.For me,these books have been the best source to learn about contemporary China,its people,society,foreign policy and the driving spirit behind the country’s remarkable success.
基金supported by the National Natural Science Foundation of China(No.52102140)Shanghai Pujiang Program(No.21PJD024)+2 种基金the Major Science and Technology Projects of Yunnan Precious Metals Laboratory Co.,Ltd(No.YPML-2023050205)the Science and Technology Plan Project of Yunnan Precious Metals Laboratory Co.,Ltd(No.YPML-2023050208)the Open Project of Yunnan Precious Metals Laboratory Co.,Ltd(No.YPML-2023050280).
文摘As machine learning(ML)continues to advance in the field of materials science,the variation in strategies for the same steps of the ML workflow becomes increasingly significant.These details can have a substantial impact on results,yet they have not received the deserved attention.This review aims to explore the various strategies available for each detail within the general workflow of materials ML.Firstly,the general workflow of materials ML will be introduced to help readers gain an understanding of potential details.Subsequently,different strategies of details within each step of the workflow will be presented through state-of-the-art case studies.The potential outcomes associated with choosing different strategies to details will be explored.Following this,suitable strategies for details will be recommended based on distinct application scenarios.Finally,directions for the future development of materials ML concerning details will be proposed.Through these discussions,we aspire to offer a comprehensive understanding of the nuances in details within materials ML.This will serve as valuable reference and guidance for researchers in both materials science and ML.
文摘Interview time: August 16, 2006 Figure in focus: Wang Jun, Director of Sales & Marketing of Plaza Hotel Wang Jun, Director of Sales and Marketing at the Plaza Hotel, has worked as a senior officer for top-ranking hotels over the past 15 years. And now, he is pursuing higher goals in his new career at the Plaza Hotel. During the interview, his kindness and modesty left a deep impression. He is efficient, conscientious and always pleasant to everyone,
