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NiTi-NbTi原位复合材料的Lüders带型变形和载荷转移行为 被引量:1
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作者 姜江 郝世杰 +3 位作者 姜大强 郭方敏 任洋 崔立山 《金属学报》 SCIE EI CAS CSCD 北大核心 2021年第7期921-927,共7页
采用电弧熔炼、锻造和拔丝方法原位合成了一种高Nb含量的NiTi-NbTi记忆合金复合材料。TEM显微分析显示,在材料内部纳米尺度的NbTi和NiTi纤维沿丝材轴向交替分布,NbTi纤维体积分数高达约70%。通过同步辐射高能X射线原位拉伸实验研究了复... 采用电弧熔炼、锻造和拔丝方法原位合成了一种高Nb含量的NiTi-NbTi记忆合金复合材料。TEM显微分析显示,在材料内部纳米尺度的NbTi和NiTi纤维沿丝材轴向交替分布,NbTi纤维体积分数高达约70%。通过同步辐射高能X射线原位拉伸实验研究了复合材料的变形机制。结果显示,虽然NiTi体积分数仅约30%,但复合材料的变形仍受NiTi的应力诱发相变控制。在加载初期,复合材料先发生均匀变形,并且在拉伸曲线出现屈服平台之前,NiTi已发生均匀相变。当平台出现之后,NiTi转而发生Lüders带型相变,进而诱发NbTi也随之发生Lüders带型变形,使整个复合材料都展现Lüders带型变形。Lüders带前沿存在载荷转移现象,载荷由正在发生相变的B2-NiTi同时转移到NbTi相及之前在均匀相变过程中形成的B19’-TiNi马氏体相。 展开更多
关键词 NiTi-NbTi复合材料 形状记忆合金 ders带型变形
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On the Lüders band formation and propagation in NiTi shape memory alloys
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作者 Bashir S.Shariat Yingchao Li +2 位作者 Hong Yang Yunzhi Wang Yinong Liu 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第21期22-29,共8页
Near-equiatomic NiTi shape memory alloys are known to exhibit Lüders-type deformation associated with a stress-induced transformation.Many studies have been conducted in the past mainly focusing on the macroscopi... Near-equiatomic NiTi shape memory alloys are known to exhibit Lüders-type deformation associated with a stress-induced transformation.Many studies have been conducted in the past mainly focusing on the macroscopic characteristics of the phenomenon and some theories have been proposed in the literature to explain its mechanisms,but some aspects of this phenomenon are still unclear,particularly at the microscopic scale.This study investigated the local strain evolution during the initiation and propagation of Lüders band in a pseudoelastic NiTi alloy during tensile deformation by means of digital image correlation(DIC)analysis.Based on the evidence collected,distinct stages of Lüders band formation and propagation are defined and the corresponding local strain rates are obtained.These local strain rates are much higher than the global strain rate of the testing,giving insight to the mechanism of this phenomenon. 展开更多
关键词 Shape memory alloy(SMA) NITI Martensitic transformation ders-type deformation ders band Digital image correlation(DIC)
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碳化物演变对冷轧ART 0.1C-7Mn钢Lüders行为影响 被引量:5
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作者 田亚强 毕文强 +3 位作者 潘红波 李红斌 郑小平 陈连生 《钢铁研究学报》 CAS CSCD 北大核心 2020年第6期505-511,共7页
采用SEM、XRD、力学性能测试等实验分析方法对冷轧中锰钢(0.1C-7Mn)在奥氏体逆相变不同温度退火过程中碳化物演变对Lüders应变的影响进行了分析。结果表明:随着退火温度的升高,碳化物先析出后溶解,在640℃退火时碳化物全部溶解,逆... 采用SEM、XRD、力学性能测试等实验分析方法对冷轧中锰钢(0.1C-7Mn)在奥氏体逆相变不同温度退火过程中碳化物演变对Lüders应变的影响进行了分析。结果表明:随着退火温度的升高,碳化物先析出后溶解,在640℃退火时碳化物全部溶解,逆转变奥氏体的稳定性适中,强塑积最高为25 GPa·%。退火温度偏低导致奥氏体稳定性过高,同时碳化物会抑制位错运动,使得屈服点延伸较为明显;退火温度适中则高密度位错开始回复,变形时能持续地产生TRIP效应硬化基体,提高材料的综合性能;退火温度偏高时,碳化物的溶解导致位错对消重排,Lüders应变消失,奥氏体稳定性降低,应变诱导马氏体快速形成,导致中锰钢抗拉强度较高但均匀伸长率降低。 展开更多
关键词 中锰TRIP钢 两相区退火 残余奥氏体 碳化物 ders应变
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基于P2P的DERS系统的研究与实现
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作者 汪方正 《电脑知识与技术》 2010年第9X期7468-7469,共2页
基于P2P的远程教育资源共享平台的定义,简单地说就是基于P2P网络或者说在P2P的网络环境中实现远程教育中的资源共享。在该课题的研究中,采用技术手段研发资源共享平台,结合C/S和P2P网络各自的优势在远程教育中有效实现资源的共享,为远... 基于P2P的远程教育资源共享平台的定义,简单地说就是基于P2P网络或者说在P2P的网络环境中实现远程教育中的资源共享。在该课题的研究中,采用技术手段研发资源共享平台,结合C/S和P2P网络各自的优势在远程教育中有效实现资源的共享,为远程教育中优质资源的整理奠定基础。 展开更多
关键词 P2P 远程教育 ders 资源共享
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Effect of Lüders Bands by Strain Ageing on Strain Distribution,Microstructure and Texture Evolution of High-Strength Pipe Steel
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作者 Jian Han Jun Wang +6 位作者 Sunusi Marwana Manladan Yangchuan Cai Qian Wang Zhixiong Zhu Lisong Zhu Lianzhong Lu Zhengyi Jiang 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2021年第5期657-667,共11页
In this study,the high-strength pipe steel,i.e.X80,was heated at 260℃for half an hour followed by air cooling for thermal simulation of pipe coating process.During the uniaxial loading of the specified tension sample... In this study,the high-strength pipe steel,i.e.X80,was heated at 260℃for half an hour followed by air cooling for thermal simulation of pipe coating process.During the uniaxial loading of the specified tension samples,the migration behaviour of Lüders bands and the re-distribution of stress after strain ageing heat treatment were investigated using digital image correlation.Digital image correlation was adopted to characterise the local axial and shear strain fields of samples that were extracted from different locations across the wall thickness of the high-strength pipe steel,and electron backscatter diffraction was used to compare the evolution of crystallographic texture among these locations.Other characterisation methods regarding microstructure and mechanical properties were conducted meanwhile,including optical microscopy,scanning electron microscopy and X-ray diffraction to accurately define the detailed performances that strain ageing,i.e.being heated to 260℃for half an hour,has led to.The obtained results show that the Lüders band-related microstructure,dislocation density,lattice constant and texture vary at the different locations across the wall thickness and influence the fi nal mechanical properties of the selected high-strength pipe steel. 展开更多
关键词 High-strength pipe steel ders band Strain ageing Stress distribution TEXTURE Mechanical property
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Acquire A Full Understanding of the Guidelines for Running CAS in the New Era and Promote the Knowledge Innovation Program in An All-round Way
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作者 Lu Yongxiang(Chinese Academy of Sciences) 《Bulletin of the Chinese Academy of Sciences》 2002年第1期11-21,共11页
Editor's note: We are sorry that because of the over-crowded space in our last issue, we are delayed in presenting the second part of the report delivered by the CAS President Lu Yongxiang at the 2002 working conf... Editor's note: We are sorry that because of the over-crowded space in our last issue, we are delayed in presenting the second part of the report delivered by the CAS President Lu Yongxiang at the 2002 working conference of CAS. The report appears in two installments in this and the 1st issue of this volume. 展开更多
关键词 der Acquire A Full Understanding of the Guidelines for Running CAS in the New Era and Promote the Knowledge Innovation Program in An All-round Way CAS Innovation
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Fe-Mo-B-CSINTERED STE ELS PRODUCED BY ADDITI ON OF MASTER ALLOY POWDERS 被引量:26
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作者 Z. M. Xiu1) , L. X. Ding2) , Z. J. Zhao3) , J. You3) , Z. Zhang3) , F. M. He1)and X. D. Sun1)1) School of Materials and Metallurgy , Northeastern University , Shenyang 110006 , China2) Department of Materials , School of Mechan 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1999年第5期1198-1201,共4页
Addition of Fe B C and Fe Mo B C m aster alloy pow ders to Fe Mo B Csintered steels can ac tivate the sintering process by liquid phase sintering . The for m ation of liquid ( α- Fe + ( Fe , Mo... Addition of Fe B C and Fe Mo B C m aster alloy pow ders to Fe Mo B Csintered steels can ac tivate the sintering process by liquid phase sintering . The for m ation of liquid ( α- Fe + ( Fe , Mo) 2 B+ Fe3( B, C) → L) i m proves m echanical properties of the steels , and ultim ate tensilestrengths of 684 774 M Pa , i m pact energy of 47 ±7 Jand elongation of 2 5 ±0 9 were ob tained . Optim u m a mount of liquid phase exists , and alarge a mount of liquid phase will re sult in the form ation of continuous netw ork of liquid phase that is detrim ental to strength andelongation . 展开更多
关键词 m aster alloy po w der DENSIFICATION SHRINKAGE
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PRODUCTION OF ULTRA-FINEα-AL_2O_3 PO WDERSFROM AMMONIUM A LUMINUM CARBONATE HY DROXIDE
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作者 F. Zhang1) , X. D. Sun1) , J. You2) , Z. Zhang2) , L. X. Ding3)and Y. M. Wang3)1) School of Materials and Metallurgy , Northeastern University , Shenyang 110006 , China2) Liaoning Analyzing and Testing Research Center , Shenyang 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1999年第5期1194-1197,共4页
Synthesis of a m m oniu m alu min u m carbonate hydroxide ( A A C H) w as investigated usinga m m oniu m alu min u m sulfate and a m moniu m hydro carbonate as the starting m aterials . Itw as found that A A C Hca... Synthesis of a m m oniu m alu min u m carbonate hydroxide ( A A C H) w as investigated usinga m m oniu m alu min u m sulfate and a m moniu m hydro carbonate as the starting m aterials . Itw as found that A A C Hcan be synthesized by adding a m m oniu m alu m inu m sulfate solution torapidly stirred a m moniu m hydro - carbonate solution at a tem perature of 30 ℃. A A C Hcantransfor m to α Al2 O3 co m pletely by calcining at 1100 ℃ for 1 hour , and the obtained po w ders , with a particle size of 100 n m , can be sintered to 98 99 % relative density at 1500 ℃for 2 hours . 展开更多
关键词 a m moniu m alu m inu m carbonate hydroxide α alu mina ultra - finepow der SINTERING
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Hard-to-Soft Transition in Radial Buckling of Multi-Concentric Nanocylinders
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作者 Sung-Jin Park Motohiro Sato +1 位作者 Tetsuro Ikeda Hiroyuki Shima 《World Journal of Mechanics》 2012年第1期42-50,共9页
We investigate the cross-sectional buckling of multi-concentric tubular nanomaterials, which are called multiwalled carbon nanotubes (MWNTs), using an analysis based on thin-shell theory. MWNTs under hydrostatic press... We investigate the cross-sectional buckling of multi-concentric tubular nanomaterials, which are called multiwalled carbon nanotubes (MWNTs), using an analysis based on thin-shell theory. MWNTs under hydrostatic pressure experience radial buckling. As a result of this, different buckling modes are obtained depending on the inter-tube separation d as well as the number of constituent tubes N and the innermost tube diameter. All of the buckling modes are classified into two deformation phases. In the first phase, which corresponds to an elliptic deformation, the radial stiffness increases rapidly with increasing N. In contrast, the second phase yields wavy, corrugated structures along the circumference for which the radial stiffness declines with increasing N. The hard-to-soft phase transition in radial buckling is a direct consequence of the core-shell structure of MWNTs. Special attention is devoted to how the variation in d affects the critical tube number Nc, which separates the two deformation phases observed in N -walled nanotubes, i.e., the elliptic phase for N Nc. We demonstrate that a larger d tends to result in a smaller Nc, which is attributed to the primary role of the interatomic forces between concentric tubes in the hard-to-soft transition during the radial buckling of MWNTs. 展开更多
关键词 Carbon NANOTUBE BUCKLING RADIAL CORRUGATION High Pressure Phenomenon Van der WAALS Coupling Multiple CORE-SHELL Structure Thin Shell Theory
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Understanding the deformability of 2D van der Waals materials from the perspective of chemical bonds
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作者 Haoran Huang Zhiqiang Gao +4 位作者 Ling Fu Kunpeng Zhao Jiawei Zhang Tian-Ran Wei Xun Shi 《npj Computational Materials》 2025年第1期337-344,共8页
Exceptional room-temperature plastic deformability has been recently uncovered in a series of two-dimensional(2D)van der Waals(vdW)crystals,adding a new facet to these materials alongside the rich physical properties.... Exceptional room-temperature plastic deformability has been recently uncovered in a series of two-dimensional(2D)van der Waals(vdW)crystals,adding a new facet to these materials alongside the rich physical properties.Although several mechanisms have been proposed to interpret the deformation of specific materials,a deep and systematic understanding is still missing to rationalize and compare the deformability for a variety of vdW materials.In this work,focusing on typical hexagonal vdW crystals such as graphite,h-BN,transition metal dichalcogenides(TMDCs),and IIIA-VIA compounds,the deformation parameters(slip barrier energy,cleavage energy,elastic modulus)and bond features are calculated,and their correlations are systematically studied.Noticeably,there is a strong positive relation between cross-layer slip/cleavage energy,in-plane modulus,and the intralayer bond strength.The IIIA-VIA compounds(GaS,GaSe,InSe)are predicted to show a larger deformability factor,probably due to their weaker and softer chemical bonds.Moreover,it is anticipated that the deformability can be further modulated by constructing superlattice structures.These findings will facilitate the understanding and development of a variety of deformable 2D inorganic semiconductors as both few-layers and bulks. 展开更多
关键词 rationalize compare deformability van der waals materials DEFORMABILITY chemical bonds interpret deformation MATERIALS deep systematic understanding cleavage energy
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基于洋流能的水下涡激振动能量俘获系统动力学特性研究
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作者 刘丽兰 任航 +1 位作者 汪甡 李佳佳 《工程科学与技术》 北大核心 2026年第1期253-265,共13页
随着清洁可再生能源的不断发展,利用洋流能为水下微型无线传感器提供电能已成为研究热点。水下涡激振动能量俘获系统是一种在浅海低流速条件下利用涡激振动效应俘获洋流能的发电装置。本文将非线性恢复力、单向轴承及齿轮齿条机构与振... 随着清洁可再生能源的不断发展,利用洋流能为水下微型无线传感器提供电能已成为研究热点。水下涡激振动能量俘获系统是一种在浅海低流速条件下利用涡激振动效应俘获洋流能的发电装置。本文将非线性恢复力、单向轴承及齿轮齿条机构与振动钝体结合,提出一种新型基于洋流能的涡激振动能量俘获系统。采用Van der Pol方程描述流体和钝体间的耦合效应,建立系统流-固-电耦合动力学方程。对系统进行稳定性分析,得到系统在单稳、双稳及三稳态情况下的参数数值范围,将3种稳态下系统的振幅比进行对比,发现系统处于三稳态时具有较强的发电优势。借助数值仿真,通过钝体振动的时域图、相图、分岔图及庞加莱截面详细研究流体参数(水流流速)和结构参数(质量比和阻尼比)对系统位移响应的影响,并分析单向轴承对传动轴转速的影响。分析质量比和阻尼比对发电功率的影响。结果表明,三稳态系统拥有非常丰富的非线性动力学行为,出现混沌运动、多周期运动及准周期运动,阻尼比的变化主要影响发电功率的峰值,而质量比的变化主要影响涡激振动的共振区间范围。 展开更多
关键词 涡激振动 能量俘获 Van der Pol方程 三稳态 流固耦合
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Modeling challenges and potential solutions for integration of emerging DERs in DMS applications: power flow and short-circuit analysis 被引量:5
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作者 Luka V.STREZOSKI Nikola R.VOJNOVIC +3 位作者 Vladimir C.STREZOSKI Predrag M.VIDOVIC Marija D.PRICA Kenneth A.LOPARO 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2019年第6期1365-1384,共20页
We aim to systematically review challenges imposed by emerging distributed energy resources(DERs)to model in two basic distribution management system(DMS)online applications—power flow and short-circuit analysis,as w... We aim to systematically review challenges imposed by emerging distributed energy resources(DERs)to model in two basic distribution management system(DMS)online applications—power flow and short-circuit analysis,as well as to offer a systematic review of potential solutions.In the last decade,electronically coupled DERs became increasingly popular.DERs can employ a wide range of control strategies for power,current,or voltage control,in both normal and faulted conditions.Therefore,DERs cannot be modeled with the traditional PQ(load or generator bus)or PV(generator bus)bus types used for modeling synchronous and induction machines in online power flow calculations.Moreover,since fault currents of DERs are limited to predefined maximal values,electronically coupled DERs cannot be represented with traditional voltage source behind impedance models for online short-circuit calculation(SCC).However,most of the DMS software packages still use the traditional models to represent all DER types,including those that are electronically coupled.This paper shows that there will be large calculation errors in such practice,which make the system model an inadequate representation of the system.This will lead to serious errors in the management,control,and operation of distribution systems.Nonetheless,potential solutions to the challenges are systematically reviewed.Finally,the calculation results on a distribution test system with all DER types are used to prove the claim. 展开更多
关键词 Distributed energy resources(ders) Distribution management system(DMS) Power flow MODELING SHORT-CIRCUIT MODELING
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Negative Coulomb drag between graphene quantum Hall edges
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作者 SONG Junwei GAN Qikang +4 位作者 ZHU Wang WATANABE Kenji TANIGUCHI Takashi YU Geliang WANG Lei 《物理学进展》 北大核心 2026年第1期1-12,共12页
Coulomb drag refers to the phenomenon in which a current driven through one conducting layer induces a voltage nearby,electrically isolated layer sorely through interlayer Coulomb interactions between charge carriers.... Coulomb drag refers to the phenomenon in which a current driven through one conducting layer induces a voltage nearby,electrically isolated layer sorely through interlayer Coulomb interactions between charge carriers.It has been extensively studied in various systems,including parallel nanowires,double quantum wells,and double-layer graphene.Here,we report the observation of Coulomb drag in a novel system consisting of two graphene layers separated laterally by a 30 nm gap within the material plane,exhibiting behavior distinct from that in vertical graphene heterostructures.Our experiments reveal pronounced negative drag resistances under an out-of-plane magnetic field at the quantum Hall edges,reaching a maximum when the carrier densities in both graphene layers are tuned to the charge neutrality point via gate voltages.Our work establish two separate and spatially closed quantum Hall edge modes as a new platform to explore electronic interaction physics between one dimensional systems. 展开更多
关键词 negative Coulomb drag quantum Hall edges van der Waals heterostructures
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SECOND ORDER DIFFRACTION FORCES ON HORIZONTAL CYLINDERS
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作者 G.X.Wu R.EatockTaylor 《Journal of Hydrodynamics》 SCIE EI CSCD 1989年第2期55-65,共11页
The second order diffraction forces on a floating semicircular cylinder and a submerged circular cylinder are calculated using the method of Lighthill(ref.3). The first order potential is obtained by the multipole exp... The second order diffraction forces on a floating semicircular cylinder and a submerged circular cylinder are calculated using the method of Lighthill(ref.3). The first order potential is obtained by the multipole expansion and numerical results are provided. 展开更多
关键词 der SECOND ORDER DIFFRACTION FORCES ON HORIZONTAL CYLINders BODY
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Enhancing Heat Transfer in X-ray Tube by van der Waals Heterostructures-based Thermionic Emission
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作者 LI Qian-qian HUANG Sun-chao +8 位作者 CHEN Su-guo WANG Yue SHI Xi-hang ZHANG Xiao-qiu-yan HU Min ZHANG Ping WANG Shao-meng ZHANG Chao GONG Yu-bin 《真空电子技术》 2026年第1期21-27,共7页
Van der Waals(vdW)heterostructures have attracted much attention due to their distinctive optical,electrical,and thermal properties,demonstrating promising potential in areas such as photocatalysis,ultrafast photonics... Van der Waals(vdW)heterostructures have attracted much attention due to their distinctive optical,electrical,and thermal properties,demonstrating promising potential in areas such as photocatalysis,ultrafast photonics,and free electron radiation devices.Particularly,they are promising platforms for studying thermionic emission.It is illustrated that using vdW heterostructure-based thermionic emission can enhance heat transfer in vacuum devices.As a proof of concept,the approach is demonstrated to offer a promising solution for the long-standing overheating issue in X-ray tubes.Specifically,it is shown that the saturated target temperature of a 2000 W X-ray tube can be reduced from around 1200℃ to 490℃.Additionally,it is also demonstrated that by reducing the height of the Schottky barrier formed in the vdW heterostructures,the thermionic cooling performance can be enhanced.The findings pave the way for the development of high-power X-ray tubes. 展开更多
关键词 X-ray tube Heat transfer Thermionic emission Thermionic cooling Van der Waals Heterostructures
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The resonance scattering of underwater elastic cylinders
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作者 JING Tinghua, WANG Runtian, ZHOU Genxiang WU Zhihao, XU Zhe and FENG Shaosong(institude of Acoustics, Academia sinica) 《Chinese Journal of Acoustics》 1990年第3期241-248,共8页
If the frequency of the incident sound wave coincides with one of the eigenfrequencies of the underwater elastic cylinder, the corresponding eigenvibration will be excited by incident sound wave and strongly reradiate... If the frequency of the incident sound wave coincides with one of the eigenfrequencies of the underwater elastic cylinder, the corresponding eigenvibration will be excited by incident sound wave and strongly reradiate sound wave towards surronding water. It has been revealed by previous investigations that the amplitude of backscattering sound appears to be minimum at the eigenfrequencies of the underwater metallic cylinders because of the destructive interference between reradiated wave of the eigenvibration and the geometrical reflected wave from surface of the cylinders. In this paper, a new phenomenon has been revealed. The amplitude of backscattering sound appears to be maximum at the eigenfrequencies of a cylinder made from nonmetallic material in which the velocity of elastic transverse wave is less than the sound velocity in water. 展开更多
关键词 der The resonance scattering of underwater elastic cylinders NYLON
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Building Peaceful Borders
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作者 By ZHANG LIJUN The author is with the China Institute of International Studies 《Beijing Review》 2006年第25期10-11,共2页
China's efforts to build a harmonious world begin with establishing peaceful borders with its neighbors China's recent contribution to the world of international relations is the promotion of "building a ... China's efforts to build a harmonious world begin with establishing peaceful borders with its neighbors China's recent contribution to the world of international relations is the promotion of "building a harmonious world together," put forward by President Hu Jintao at the 60th anniversary of the UN in September 2005. As the core of the country's peaceful foreign policy in the new era, this approach has been well received and widely discussed in the international community. Meanwhile, Chinese foreign pol... 展开更多
关键词 Building Peaceful Borders der
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FLOW PROPERTIES OF COHESIVE NANOPOWDERS
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作者 Jgen Tomas 《China Particuology》 SCIE EI CAS CSCD 2003年第6期231-241,共11页
The fundamentals of cohesive powder consolidation and flow behaviour using a reasonable combination of particle and continuum mechanics are explained. By means of the model 搒tiff particles with soft contacts? the inf... The fundamentals of cohesive powder consolidation and flow behaviour using a reasonable combination of particle and continuum mechanics are explained. By means of the model 搒tiff particles with soft contacts? the influ-ence of elastic-plastic repulsion in particle contacts is demonstrated. With this as the physical basis, the stationary yield locus, instantaneous yield loci and consolidation loci, flow function and compression function are presented. The flow properties of a very cohesive titania nanopowder (dS=200 nm) are shown. These models are used to evaluate shear cell test results as constitutive functions for computer aided apparatus design for reliable powder flow. 展开更多
关键词 particle mechanics adhesion force van der Waals forces constitutive models cohesive powder flow properties
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建筑新型供配电系统探讨 被引量:1
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作者 李慧 《建筑电气》 2025年第9期8-13,共6页
根据国家标准、IEC标准和相关行业标准,从零碳建筑的能源特点,供配电系统架构、关键组成部分、能量管理和负荷调控策略等方面,探讨建筑新型供配电系统类型及基本特征。
关键词 建筑新型供配电系统 区域/本地EPS 微电网 产消式低压电气系统(PEI) 分布式电源(DER) 可控负荷 虚拟电厂 分散式电能系统 并网点(POC) 公共连接点(PCC)
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Helsmoortel-Van der Aa综合征1例并文献复习
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作者 刘颖 潘一新 +2 位作者 陈太芳 唐辉振 赵婧娴 《中国热带医学》 北大核心 2025年第9期1225-1228,共4页
Helsmoortel-Van der Aa综合征(HVDAS)是一种罕见的神经发育障碍性疾病,主要由活性依赖性神经保护蛋白(ADNP)基因突变引起,是最常见的孤独症谱系障碍(ASD)单基因病因之一。本文分析2024年就诊于海口市妇幼保健院的1例患儿,男,3岁10个月... Helsmoortel-Van der Aa综合征(HVDAS)是一种罕见的神经发育障碍性疾病,主要由活性依赖性神经保护蛋白(ADNP)基因突变引起,是最常见的孤独症谱系障碍(ASD)单基因病因之一。本文分析2024年就诊于海口市妇幼保健院的1例患儿,男,3岁10个月,因“运动、语言发育迟缓2年余,社交障碍1年余”入院,检查发现患儿存在孤独症谱系障碍、全面发育迟缓、特殊面容、矮小、脑积水等临床表现,基因检测发现患儿携带ADNP基因杂合突变{NM_001282531.3(ADNP):c.2189(exon6)delG[p.(Arg730Glnfs3)]},其父母及妹妹均未携带该突变。总结临床资料并结合文献复习,ADNP基因在染色质重塑和神经发育障碍中发挥重要作用,ADNP基因突变可累及多系统。此例HVDAS具有典型临床表现,并拓宽了脑积水的表型谱,为此类基因变异的遗传咨询以及临床医师的早期识别提供了参考依据。 展开更多
关键词 ADNP基因 Helsmoorte1-Van der Aa综合征 孤独症谱系障碍 发育迟缓 脑积水
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