The electrochemical behavior of trifluoperazine at decanethiol self-assembledmonolayer(SAM)modified gold electrodes(i.e.C_(10)H_(21)SH/Au)has been studied,Trifluoperazine can effectively accumulate on C_(10)H_(21)SH/A...The electrochemical behavior of trifluoperazine at decanethiol self-assembledmonolayer(SAM)modified gold electrodes(i.e.C_(10)H_(21)SH/Au)has been studied,Trifluoperazine can effectively accumulate on C_(10)H_(21)SH/Au electrodes and generate asensitive anodic peak at about 0.63 V(vs.SCE)in 0.05 mol/L pH 9.4 Na_2 B_4 O_7 buffer solution.Under the selected conditions,the anodic peak current was linear to trifluoperazine concentrationin the range of 5.0 X 10^(-7)-3.O X 10^(-3)mol/Lwith correlation coefficient of 0.997,thedetection limit was 3.0 X 10^(-5)mol/L.This method was applied to the determination oftrifluoperazine in drug samples and the recovery was 97.3%-104.0%It was found that sodium dodecylsulfate(SDS)could make the anodic peak current increase.In the presence of SDS,the peak at about0.63 V turned into two peaks,resulting from the change of the electrochemical mechanism.展开更多
基金Supported by the National Natural Science Foundation of China(20173040)
文摘The electrochemical behavior of trifluoperazine at decanethiol self-assembledmonolayer(SAM)modified gold electrodes(i.e.C_(10)H_(21)SH/Au)has been studied,Trifluoperazine can effectively accumulate on C_(10)H_(21)SH/Au electrodes and generate asensitive anodic peak at about 0.63 V(vs.SCE)in 0.05 mol/L pH 9.4 Na_2 B_4 O_7 buffer solution.Under the selected conditions,the anodic peak current was linear to trifluoperazine concentrationin the range of 5.0 X 10^(-7)-3.O X 10^(-3)mol/Lwith correlation coefficient of 0.997,thedetection limit was 3.0 X 10^(-5)mol/L.This method was applied to the determination oftrifluoperazine in drug samples and the recovery was 97.3%-104.0%It was found that sodium dodecylsulfate(SDS)could make the anodic peak current increase.In the presence of SDS,the peak at about0.63 V turned into two peaks,resulting from the change of the electrochemical mechanism.
