Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investiga...Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific studies.Our study seeks to establish reference values for hematological and biochemical parameters of four lineages of mice.Methods:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages Swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 mice.Analysis were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical parameters.Results:Results are shown as means and standard deviation,grouped by lineage and genre.Comparing the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual variability.Conclusion:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model.展开更多
Fiber-reinforced silica ceramic matrix composites(SiO_(2) f/SiO_(2))have gained extensive attention in recent years for its applications in aeronautics field such as radar radome and window.However,the machining prope...Fiber-reinforced silica ceramic matrix composites(SiO_(2) f/SiO_(2))have gained extensive attention in recent years for its applications in aeronautics field such as radar radome and window.However,the machining properties and mechanism of the material remain unclear.The features and mechanical properties of the material itself have a significant influence on both its machining characteristics and surface integrity.Thus,a full-factor grinding experiment is conducted using a 3 D orthogonal SiO_(2) f/SiO_(2) aiming to obtain its machining characteristics.The effects of grinding parameters and tools on the grinding force,surface roughness,and material damage type are investigated using a dynamometer,Scanning Electron Microscope(SEM),and Acoustic Emission(AE)analysis.The AE frequency band is analyzed,and a semi-analytical force model is established to study the difference between a single grain and wheel grinding.It was found that the changes in surface roughness correlate with the changes in grinding force,with fiber fracture being the main reason behind the increase in grinding force.Finally,the material removal mechanism was studied based on the AE analysis.It was found that the removal mechanism is fiber fracture dominated with matrix crack and debonding,and the primary sources of energy consumption are fiber fracture and friction.展开更多
High-resolution atomic-beam laser spectroscopy has been performed to study Stark effect of Ba atom. Stark spectra have been observed at various electric fields for Ba highly excited states. The scalar polarizability o...High-resolution atomic-beam laser spectroscopy has been performed to study Stark effect of Ba atom. Stark spectra have been observed at various electric fields for Ba highly excited states. The scalar polarizability of the transition from 6s5d3D2 to 5d6p3F3 at 728.0 nm and the tensor polarizability of the 3F3 level have been determined for the first time, to be αs = -89.8 (12) kHz/(kV/cm)2 and αt = -133.7 (20) kHz/(kV/cm)2, respectively.展开更多
基金National Council for Scientific and Technological Development(CNPq)Coordination for the Improvement of Higher Level Personnel,Brazil(CAPES)Research Support Foundation for the State of Rio de Janeiro,Brazil(FAPERJ)。
文摘Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific studies.Our study seeks to establish reference values for hematological and biochemical parameters of four lineages of mice.Methods:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages Swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 mice.Analysis were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical parameters.Results:Results are shown as means and standard deviation,grouped by lineage and genre.Comparing the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual variability.Conclusion:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model.
基金supported by the National Natural Science Foundation of China(Nos.51375333 and 51805365)。
文摘Fiber-reinforced silica ceramic matrix composites(SiO_(2) f/SiO_(2))have gained extensive attention in recent years for its applications in aeronautics field such as radar radome and window.However,the machining properties and mechanism of the material remain unclear.The features and mechanical properties of the material itself have a significant influence on both its machining characteristics and surface integrity.Thus,a full-factor grinding experiment is conducted using a 3 D orthogonal SiO_(2) f/SiO_(2) aiming to obtain its machining characteristics.The effects of grinding parameters and tools on the grinding force,surface roughness,and material damage type are investigated using a dynamometer,Scanning Electron Microscope(SEM),and Acoustic Emission(AE)analysis.The AE frequency band is analyzed,and a semi-analytical force model is established to study the difference between a single grain and wheel grinding.It was found that the changes in surface roughness correlate with the changes in grinding force,with fiber fracture being the main reason behind the increase in grinding force.Finally,the material removal mechanism was studied based on the AE analysis.It was found that the removal mechanism is fiber fracture dominated with matrix crack and debonding,and the primary sources of energy consumption are fiber fracture and friction.
文摘High-resolution atomic-beam laser spectroscopy has been performed to study Stark effect of Ba atom. Stark spectra have been observed at various electric fields for Ba highly excited states. The scalar polarizability of the transition from 6s5d3D2 to 5d6p3F3 at 728.0 nm and the tensor polarizability of the 3F3 level have been determined for the first time, to be αs = -89.8 (12) kHz/(kV/cm)2 and αt = -133.7 (20) kHz/(kV/cm)2, respectively.
