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Current management of cryptoglandular fistula-in-ano 被引量:7
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作者 Joshua IS Bleier Husein Moloo 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第28期3286-3291,共6页
Fistula-in-ano is a difficult problem that physicians have struggled with for centuries.Appropriate treatment is based on 3 central tenets: (1) control of sepsis;(2) closure of the fistula;and (3) maintenance of conti... Fistula-in-ano is a difficult problem that physicians have struggled with for centuries.Appropriate treatment is based on 3 central tenets: (1) control of sepsis;(2) closure of the fistula;and (3) maintenance of continence.Treatment options continue to evolve-as a result,it is important to review old and new options on a regular basis to ensure that our patients are provided with up to date information and options.This paper will briefly cover some of the traditional approaches that have been used as well as some newer promising procedures. 展开更多
关键词 cryptoglandular FISTULA ANORECTAL Sphincter sparing Ligation of the intersphincteric fistula tract procedure
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Necrotizing fasciitis of cryptoglandular infection treated with multiple incisions and thread-dragging therapy:A case report 被引量:2
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作者 Xiao-Chun Tao De-Chang Hu +2 位作者 Li-Xin Yin Chen Wang Jin-Gen Lu 《World Journal of Clinical Cases》 SCIE 2021年第28期8537-8544,共8页
BACKGROUND Necrotizing fasciitis is a fulminant necrotizing soft tissue disease with a high fatality rate.It always starts with impact on the deep fascia rapidly and might result in secondary necrosis of the subcutane... BACKGROUND Necrotizing fasciitis is a fulminant necrotizing soft tissue disease with a high fatality rate.It always starts with impact on the deep fascia rapidly and might result in secondary necrosis of the subcutaneous tissue,fascia,and muscle.Thus,timely and multiple surgical operations are needed for the treatment.Meanwhile,the damage of skin and soft tissue caused by multiple surgical operations may require dermatoplasty and other treatments as a consequence.CASE SUMMARY Here,we report a case of 50-year-old male patient who was admitted to our hospital with symptoms of necrotizing fasciitis caused by cryptoglandular infection in the perianal and perineal region.The symptoms of necrotizing fasciitis,also known as the cardinal features,include hyperpyrexia,excruciatingly painful lesions,demonstration gas in the tissue,an obnoxious foul odor and uroschesis.The results of postoperative pathology met the diagnosis.Based on the premise of complete debridement,multiple incisions combined with thread-dragging therapy(a traditional Chinese medicine therapy)and intensive supportive therapies including comprising antibiotics,nutrition and fluids were given.The outcome of the treatment was satisfactory.The patient recovered quickly and achieved ideal anal function and morphology.CONCLUSION Timely and effective debridement and multiple incisions combined with thread-dragging therapy are an integrated treatment for necrotizing fasciitis. 展开更多
关键词 Necrotizing fasciitis cryptoglandular infection Traditional Chinese medicine Multiple incisions and thread-dragging therapy Integrated treatment Case report
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Why do we have to review our experience in managing cases with idiopathic fistula-in-ano regularly?
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作者 Claudio Fucini Iacopo Giani 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第28期3297-3299,共3页
"Why do we have to review our experience in managing idiopathic fistula-in-ano regularly?" In order to answer this apparently simple question,we reviewed our clinical and surgical cases and most important re... "Why do we have to review our experience in managing idiopathic fistula-in-ano regularly?" In order to answer this apparently simple question,we reviewed our clinical and surgical cases and most important relevant literature to find a rational and scientific answer.It would appear that whatever method you adopt in fistula management,there is a price to pay regarding either rate of recurrence (higher with conservative methods) or impairment of continence (higher with traditional surgery).Since,at the moment,reliable data to identify a treatment as a gold standard in the management of anal fistulas are lacking,the correct approach to this condition must consider all the anatomic and clinicopathological aspects of the disease;this knowledge joined to an eclectic attitude of the surgeon,who should be familiar with different types of treatment,is the only guarantee for a satisfactory treatment.As a conclusion,it is worthwhile to remember that adequate initial treatment significantly reduces recurrence,which,when it occurs,is usually due to failure to recognise the tract and primary opening at the initial operation. 展开更多
关键词 Anal fistula treatment Surgery of fistulain-ano Anal cryptoglandular infections Anal abscess Recurrent fistula-in-ano
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腺源性肛周脓肿根治术后复发影响因素分析 被引量:1
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作者 魏博文 陈学静 朱晓亮 《中国肛肠病杂志》 2025年第10期52-55,共4页
目的:分析腺源性肛周脓肿根治术后复发的影响因素,为提高患者的长期疗效和减少复发提供理论依据。方法:回顾性选取2022年3月至2024年8月择期行腺源性肛周脓肿根治术患者104例为研究参与者,依据患者术后6个月是否发生复发情况将患者分为... 目的:分析腺源性肛周脓肿根治术后复发的影响因素,为提高患者的长期疗效和减少复发提供理论依据。方法:回顾性选取2022年3月至2024年8月择期行腺源性肛周脓肿根治术患者104例为研究参与者,依据患者术后6个月是否发生复发情况将患者分为复发组28例和未复发组76例。采用单因素和多因素Logistic回归分析腺源性肛周脓肿根治术后复发影响因素。结果:2组患者在性别、年龄、病程、身体质量指数、吸烟、饮酒史、合并高血压方面比较差异无统计学意义(P>0.05),而合并慢性腹泻史、糖尿病情况比较差异有统计学意义(P<0.05),复发组患者合并慢性腹泻史、合并糖尿病占比高于未复发组。2组患者在脓肿范围、切口类型、术前应用抗生素方面比较差异无统计学意义(P>0.05),在脓肿深浅、致病菌群、蹄铁型脓肿方面比较差异有统计学意义(P<0.05),复发组患者合并脓肿程度较深、致病菌群为革兰阴性菌、发生蹄铁型脓肿占比高于未复发组。Logistic回归分析结果显示,有糖尿病、慢性腹泻史、深部脓肿、革兰阴性菌感染及蹄铁型脓肿是肛周脓肿术后复发的危险因素(P<0.05)。结论:糖尿病、慢性腹泻史、深部脓肿、革兰阴性菌感染及蹄铁型脓肿是肛周脓肿术后复发的危险因素,临床医师应针对高危患者进行更严格的术前准备和术后管理,以减少复发的可能性。 展开更多
关键词 腺源性肛周脓肿 术后 复发 影响因素
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自体脂肪干细胞移植治疗复杂性肛瘘的临床观察 被引量:9
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作者 江滨 时宏珍 +7 位作者 史央 张苏闽 王业皇 倪敏 周春根 李猛 章阳 徐大超 《中华结直肠疾病电子杂志》 2019年第6期566-573,共8页
目的评估自体脂肪干细胞移植治疗复杂性肛瘘的有效性和安全性。方法纳入2018年1月到2018年10月间南京市中医院肛肠中心收治的复杂性肛瘘23例,年龄12~51岁,其中克罗恩病肛瘘11例,腺源性肛瘘12例,应用自体脂肪干细胞移植治疗,随访3~12个月... 目的评估自体脂肪干细胞移植治疗复杂性肛瘘的有效性和安全性。方法纳入2018年1月到2018年10月间南京市中医院肛肠中心收治的复杂性肛瘘23例,年龄12~51岁,其中克罗恩病肛瘘11例,腺源性肛瘘12例,应用自体脂肪干细胞移植治疗,随访3~12个月,并收集患者的临床资料。通过临床评估及MRI结果评价瘘管闭合情况,统计瘘管外口完全上皮化的时间,采用SF-36量表和VAS量表评估患者术前、术后的生活质量变化及疼痛评分变化,运用Wexner失禁评分量表评估患者术前术后的肛门失禁情况,对于克罗恩病肛瘘患者需记录其治疗前后的肛周病变活动指数(PDAI),并记录研究中的所有不良事件。结果瘘管的总愈合率为69.57%(16/23),其中克罗恩病肛瘘的愈合率为90.91%(10/11),腺源性肛瘘为50%(6/12);16名瘘管愈合患者的外口平均闭合时间为(17.06±4.54)天,其中克罗恩病肛瘘为(17.90±4.53)天,腺源性肛瘘为(15.67±4.59)天。患者的生活质量评分与疼痛评分在术后7天可恢复至术前水平,而肛门失禁评分则保持不变或降低。克罗恩病肛瘘患者治疗前和治疗后90天的PDAI评分为(8.55±1.37)分和(1.27±1.10)分,二者之间差异有统计学意义(t=12.033,P<0.05)。研究中未出现与ADSCs注射相关的不良事件。结论自体脂肪干细胞移植是治疗复杂性肛瘘特别是克罗恩病肛瘘的一种安全有效的方法,可以保护患者肛门功能,减轻术后疼痛,改善围手术期生活质量。 展开更多
关键词 肛管 脂肪干细胞 复杂性肛瘘 腺源性肛瘘 克罗恩病肛瘘 肛门功能
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腺源性肛瘘经手术治疗后创面愈合困难的危险因素分析 被引量:2
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作者 陈旭渊 罗仕云 +1 位作者 李文忠 李毅 《中华普外科手术学杂志(电子版)》 2024年第1期82-85,共4页
目的探讨腺源性肛瘘经手术治疗后创面愈合困难的危险因素。方法回顾性分析2020年1月至2023年3月期间收治114例腺源性肛瘘患者资料。均行手术治疗,依据术后创面愈合情况将患者分为愈合良好组(n=93)及愈合困难组(n=21)。使用SPSS 22.0统... 目的探讨腺源性肛瘘经手术治疗后创面愈合困难的危险因素。方法回顾性分析2020年1月至2023年3月期间收治114例腺源性肛瘘患者资料。均行手术治疗,依据术后创面愈合情况将患者分为愈合良好组(n=93)及愈合困难组(n=21)。使用SPSS 22.0统计学软件进行分析,计量资料以()表示,采用独立样本t检验;计数资料以[例(%)]呈现,采用χ2检验;通过单因素及多因素Logistic回归分析腺源性肛瘘经手术治疗后创面愈合困难的影响因素。P<0.05为差异有统计学意义。结果对所有患者进行随访4周,创面愈合困难有21例(18.4%),创面愈合良好有93例(81.6%);年龄>60岁、有糖尿病史、合并便秘、合并术后创面细菌感染、术后抗生素使用种类>2种、创面存在引流不畅均为影响腺源性肛瘘经手术治疗后创面愈合的相关危险因素(P<0.05)。结论腺源性肛瘘经手术治疗后创面愈合困难的发生风险较大,其危险因素较多,临床应针对危险因素采取针对性干预措施,以提升预后效果。 展开更多
关键词 腺源性肛瘘 肛瘘手术 创面愈合 危险因素
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