Empty-nest elderly are those who have no children or whose children are away from home,and they have to live alone or with their spouses.The prevalence of depression in the elderly is worrying,especially in the empty-...Empty-nest elderly are those who have no children or whose children are away from home,and they have to live alone or with their spouses.The prevalence of depression in the elderly is worrying,especially in the empty-nest elderly.This study aimed to examine the prevalence of depression among the empty-nest elderly in China and explore the factors that influence depression among the empty-nest elderly.Methods:We searched both international(PubMed,Cochrane Library,Embase,and Web of Science)and Chinese(CNKI,WanFang,SinoMed,and VIP)databases from their inception date until 12 April,2020,and collected cross-sectional studies on the prevalence of depression among the empty-nest elderly in China.Two reviewers independently screened the literature,extracted the data,and evaluated the risk of bias included in the study.Meta-analysis was performed using Stata12.0 software.Results:Twenty-seven cross-sectional studies were included in the meta-analysis.The pooled prevalence of depression among the empty-nest elderly in China was 41%(95%CI:32%–50%).Subgroup analysis revealed that the Geriatric Depression Scale versions,sampling methods,living areas,gender,age,chronic diseases,and living arrangements were associated with the prevalence of depression among the empty-nest elderly in China.Conclusions:The prevalence of depression among the empty-nest elderly in China was relatively high.Researchers could explore more reasons for the differences in the prevalence of depression among the empty-nest elderly from multiple perspectives in the future.Relevant departments should identify and routinely evaluate the negative emotions of the empty-nest elderly.Meanwhile,community nurses should care for the emotional needs of the empty-nest elderly,carry out targeted mental health education,and promote the realization of healthy aging.展开更多
An alternative expression for photoionization cross-section of atoms or molecules and a dielectric influence function （DIF） in a high-density system proposed recently are used to study the photoionization cross-sect...An alternative expression for photoionization cross-section of atoms or molecules and a dielectric influence function （DIF） in a high-density system proposed recently are used to study the photoionization cross-sections of solid silver. It is suggested that a density turning point （DTP） of a photoionized system may be viewed as the critical point where the photoionization properties of atoms in a real system may have a notable change. The results show that the present theoretical photoionization cross-sections are in good agreement with the experimental results of a silver crystal both in structure and in magnitude.展开更多
Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between ...Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.展开更多
OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which...OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.展开更多
Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess...Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.展开更多
BACKGROUND Helicobacter pylori(H.pylori)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in ...BACKGROUND Helicobacter pylori(H.pylori)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military personnel.Current guidelines in China state all patients with evidence of active infection with H.pylori are offered treatment.However,the prevalence of H.pylori infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment strategies.Understanding the prevalence of H.pylori infection in the military population will aid in the development of customized strategies to better manage this infectious disease.AIM To investigate the prevalence of H.pylori infection in the Chinese military population in different geographic areas.METHODS This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of China.H.pylori infection was identified using the urea breath test,which had been performed between January 2020 and December 2021.RESULTS Of the 22421 military service members,7416(33.1%)were urea breath test-positive.The highest prevalence of H.pylori was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected population.The individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,respectively.CONCLUSION H.pylori infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.展开更多
association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a ...association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a cross-sectional study in a hospital-based nursing school.EI level was measured using the Schutte Self-report Emotional Intelligence Scale(SSEIS).Results:We recruited 287 participants(mean age:21.9 years).Their mean SSEIS score was 119.6(95%CI=118.57-120.65).The mean SSEIS scores of 172 full-time and 115 part-time nurses were 120.7(95%CI=119.3-122.0)and 118.1(95%CI=116.5-119.6),respectively.There was no significant difference between the groups.Conclusion:The EI difference between full-time and part-time nursing students was statistically insignificant.The need for further EI development among both full-time and part-time students must be addressed.展开更多
Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2...Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.展开更多
Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods...Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.展开更多
The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly comple...The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.展开更多
Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12...Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.展开更多
Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a kno...Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.展开更多
AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National ...AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.展开更多
To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with...To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.展开更多
Joanna Page is Director of CRASSH and Professor of Latin American Studies at the University of Cambridge.Her research interests are generally connected to the relationship between science and culture in Latin America....Joanna Page is Director of CRASSH and Professor of Latin American Studies at the University of Cambridge.Her research interests are generally connected to the relationship between science and culture in Latin America.She has also worked on questions of memory,modernity,capitalism,posthumanism,new materialism,decoloniality,ecology,and environmental thought.This interview covers three main aspects:the characteristics of science fiction texts in Latin America,the interdisciplinary research models at the intersection of science,literature,and art,and Latin America as a field of regional studies.Professor Page starts with Argentine science fiction novels and expands the discussion to include graphic novels in Latin America,outlining the panorama of science fiction and its indigenous features.The conversation delves into the literary and technological relationships within Latin American science fiction texts.Building upon this foundation,this interview explores the interdisciplinary research paradigms concerning the relationship between science and culture,aiming to contribute to regional studies by exploring new pathways for interdisciplinary,cross-regional,and trans-media research.展开更多
Professor Paul Crosthwaite,from the School of Literature,Languages,and Cultures at the University of Edinburgh,is a prominent scholar in the interdisciplinary field of literature and economics.He is a co-editor of the...Professor Paul Crosthwaite,from the School of Literature,Languages,and Cultures at the University of Edinburgh,is a prominent scholar in the interdisciplinary field of literature and economics.He is a co-editor of the Palgrave Studies in Literature,Culture,and Economics series and The Cambridge Companion to Literature and Economics(2022).In recent years,he has significantly influenced the intersection of literature and economics,advocating particularly for a shift towards the Economic Humanities.This interview covers:1.The definition and theoretical origin of the Economic Humanities;2.The internal heterogeneity and critical limitations of the New Economic Criticism,and the theoretical advantages and potential development of the Economic Humanities;3.What research paradigms do Environmental Humanities,Medical Humanities,and Digital Humanities provide for the Economic Humanities;4.How literary researchers can work at the interface of the Economic Humanities research.As a novel interdisciplinary interface between literature and economics,Professor Paul Crosthwaite’s concept of the Economic Humanities not only pioneers methodological tools for interdisciplinary studies of literature and economics but also underscores the interpretative potential and disciplinary benefits of literary viewpoints on economics.This underscores the vital role of literature in human knowledge,meriting attention from the literary research academia.展开更多
Cohort studies are important epidemiological methods to investigate associations between environmental factors,individual characteristics,and disease or other health outcomes.As a paradigm of cohort studies,the Framin...Cohort studies are important epidemiological methods to investigate associations between environmental factors,individual characteristics,and disease or other health outcomes.As a paradigm of cohort studies,the Framingham Heart Study(FHS)is the longest-running cardiovascular epidemiological study,starting in 1948.展开更多
Rapid population aging has led to an increased focus on age-related conditions such as sarcopenia.causing loss of muscle mass and strength^([1,2]). Sarcopenia is associated with adverse outcomes,including falls, funct...Rapid population aging has led to an increased focus on age-related conditions such as sarcopenia.causing loss of muscle mass and strength^([1,2]). Sarcopenia is associated with adverse outcomes,including falls, functional decline, frailty, and mortality, which can lower the quality of life and shorten lifespan^([1,2]).展开更多
The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role i...The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role in determining the output performance of the scroll expander.In this study,in order to investigate the output characteristics of a variable cross-section scroll expander,numerical simulation and experimental studies were con-ducted by using Computational Fluid Dynamics(CFD)methods and dynamic mesh techniques.The impact of critical parameters on the output performance of the scroll expander was analyzed through the utilization of the control variable method.It is found that increasing the inlet pressure and temperature within a certain range can improve the output power of the scroll expander.However,the increase in temperature and meshing clearance leads to a decline in the overall output performance of the scroll expander,leading to a decrease in volumetric efficiency by 8.43%and 12.79%,respectively.The experiments demonstrate that under equal inlet pressure conditions,increasing the inlet temperature elevates both the rotational speed and torque output of the scroll expander.Specifically,compared to operating at normal temperatures,the output torque increases by 21.8%under high-temperature conditions.However,the rate of speed and torque variation decreases as a consequence of enlarged meshing clearance,resulting in increased internal leakage and reduction in isentropic efficiency.展开更多
BACKGROUND Depression is a significant risk factor for diabetes,particularly type 2 diabetes.However,depressive symptoms differ from clinical depression.Previous research has not fully considered the relationship betw...BACKGROUND Depression is a significant risk factor for diabetes,particularly type 2 diabetes.However,depressive symptoms differ from clinical depression.Previous research has not fully considered the relationship between the trajectory of depressive symptoms and the risk of developing diabetes over time.AIM To investigate the association between depressive symptoms,their trajectories,and the risk of developing diabetes in two prospective cohort studies.METHODS In the first phase we analyzed the association between depressive symptoms and the risk of developing diabetes separately using the Health and Retirement Study(HRS).Depressive symptom trajectories were assessed by examining changes in depressive symptoms at baseline and again 8 years later.We then identified specific depressive symptom trajectories that increased the risk of diabetes in the second phase.Finally,we confirmed the association between depressive symptoms and their trajectories with diabetes risk using the English Longitudinal Study of Ageing(ELSA)as a validation study.Depressive symptom trajectories were categorized into five states based on changes in the modified 8-item Center for Epidemiological Studies-Depression scores:Persistently high;increasing;fluctuating;decreasing;and persistently low.Diabetes mellitus was defined as self-reported,physician-diagnosed diabetes.Cox proportional hazards models were used to assess hazard ratios(HR)and 95%confidence intervals(CI),adjusting for potential confounders.RESULTS In the first phase a total of 27658 participants were included(HRS:18633,ELSA:9025),among whom 6582 had depressive symptoms(HRS:4547,ELSA:2035),6407 had somatic depressive symptoms(HRS:4414,ELSA:1993),and 26415 had cognitive-affective depressive symptoms(HRS:17755,ELSA:8660).We found that overall depressive symptoms(HRS:HR=1.14,95%CI:1.07-1.22;ELSA:HR=1.18,95%CI:1.03-1.34)and somatic depressive symptoms(HRS:HR=1.14,95%CI:1.07-1.22;ELSA:HR=1.25,95%CI:1.10-1.42)increased the risk of diabetes,while cognitive depressive symptoms were not associated with diabetes risk.Over an 8-year follow-up we identified 19729 trajectories of overall,somatic,and cognitive-affective depressive symptoms(HRS:13918,ELSA:5811).In the second phase we found that persistently high(HRS:HR=1.22,95%CI:1.06-1.40,ELSA:HR=1.54,95%CI:1.16-2.05 in total and HRS:HR=1.24,95%CI:1.07-1.43,ELSA:HR=1.79,95%CI:1.36-2.35 in somatic)and fluctuating(HRS:HR=1.09,95%CI:1.01-1.17,ELSA:HR=1.33,95%CI:1.14-1.55 in total and HRS:HR=1.10,95%CI:1.02-1.18,ELSA:HR=1.31,95%CI:1.13-1.53 in somatic)trajectories of overall and somatic depressive symptoms increased the risk of diabetes,while increasing trajectories may also raise diabetes risk.However,decreasing trajectories were not associated with diabetes risk.Cognitive-affective depressive symptoms showed no association with diabetes risk regardless of trajectory changes.Sensitivity analyses confirmed the reliability of the findings.CONCLUSION Persistently high and fluctuating trajectories of overall and somatic depressive symptoms increased the risk of diabetes,while decreasing trajectories were not associated with diabetes risk.In contrast trajectories of cognitiveaffective depressive symptoms show no relationship with diabetes risk.Focusing on depressive symptom trajectories,particularly those of somatic depressive symptoms,represented a viable strategy for future diabetes prevention.展开更多
基金This study was funded by the National Natural Science Foundation of China(No.71704133).
文摘Empty-nest elderly are those who have no children or whose children are away from home,and they have to live alone or with their spouses.The prevalence of depression in the elderly is worrying,especially in the empty-nest elderly.This study aimed to examine the prevalence of depression among the empty-nest elderly in China and explore the factors that influence depression among the empty-nest elderly.Methods:We searched both international(PubMed,Cochrane Library,Embase,and Web of Science)and Chinese(CNKI,WanFang,SinoMed,and VIP)databases from their inception date until 12 April,2020,and collected cross-sectional studies on the prevalence of depression among the empty-nest elderly in China.Two reviewers independently screened the literature,extracted the data,and evaluated the risk of bias included in the study.Meta-analysis was performed using Stata12.0 software.Results:Twenty-seven cross-sectional studies were included in the meta-analysis.The pooled prevalence of depression among the empty-nest elderly in China was 41%(95%CI:32%–50%).Subgroup analysis revealed that the Geriatric Depression Scale versions,sampling methods,living areas,gender,age,chronic diseases,and living arrangements were associated with the prevalence of depression among the empty-nest elderly in China.Conclusions:The prevalence of depression among the empty-nest elderly in China was relatively high.Researchers could explore more reasons for the differences in the prevalence of depression among the empty-nest elderly from multiple perspectives in the future.Relevant departments should identify and routinely evaluate the negative emotions of the empty-nest elderly.Meanwhile,community nurses should care for the emotional needs of the empty-nest elderly,carry out targeted mental health education,and promote the realization of healthy aging.
基金Project supported by the National Natural Science Foundation of China （Grant No 10474068） and the Natural Science Foundation of Yantai Normal University （Grant No 22270301）.
文摘An alternative expression for photoionization cross-section of atoms or molecules and a dielectric influence function （DIF） in a high-density system proposed recently are used to study the photoionization cross-sections of solid silver. It is suggested that a density turning point （DTP） of a photoionized system may be viewed as the critical point where the photoionization properties of atoms in a real system may have a notable change. The results show that the present theoretical photoionization cross-sections are in good agreement with the experimental results of a silver crystal both in structure and in magnitude.
文摘Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.
基金National Nonprofit Institute Research Grant for the Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences:Mechanism of Regulating Phlegm-Dampness Constitution to Prevent Metabolic Diseases based on Gut Microbiota-host DNA Methylation(No.YZ-202151)。
文摘OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.
基金supported by an Innovation Fund for Medical Sciences of the Chinese Academy of Medical Sciences (Grant No.2019-I2M-2-007).
文摘Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.
文摘BACKGROUND Helicobacter pylori(H.pylori)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military personnel.Current guidelines in China state all patients with evidence of active infection with H.pylori are offered treatment.However,the prevalence of H.pylori infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment strategies.Understanding the prevalence of H.pylori infection in the military population will aid in the development of customized strategies to better manage this infectious disease.AIM To investigate the prevalence of H.pylori infection in the Chinese military population in different geographic areas.METHODS This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of China.H.pylori infection was identified using the urea breath test,which had been performed between January 2020 and December 2021.RESULTS Of the 22421 military service members,7416(33.1%)were urea breath test-positive.The highest prevalence of H.pylori was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected population.The individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,respectively.CONCLUSION H.pylori infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.
文摘association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a cross-sectional study in a hospital-based nursing school.EI level was measured using the Schutte Self-report Emotional Intelligence Scale(SSEIS).Results:We recruited 287 participants(mean age:21.9 years).Their mean SSEIS score was 119.6(95%CI=118.57-120.65).The mean SSEIS scores of 172 full-time and 115 part-time nurses were 120.7(95%CI=119.3-122.0)and 118.1(95%CI=116.5-119.6),respectively.There was no significant difference between the groups.Conclusion:The EI difference between full-time and part-time nursing students was statistically insignificant.The need for further EI development among both full-time and part-time students must be addressed.
文摘Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.
基金funded by Tianjin Key Medical Discipline(Specialty)Construction Project,China(Grant No.TJYXZDXK-011A)Tianjin Medical University Cancer Institute&Hospital Nursing Special Fund Project(H2304)。
文摘Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.
基金financially supported by Guangdong Province Basic and Applied Basic Research Fund Project(Grant No.2022B1515250009)Liaoning Provincial Natural Science Foundation-Doctoral Research Start-up Fund Project(Grant No.2024-BSBA-05)+1 种基金Major Science and Technology Innovation Project in Shandong Province(Grant No.2024CXGC010803)the National Natural Science Foundation of China(Grant Nos.52271269 and 12302147).
文摘The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.
基金supported by the National Natural Science Foundation of China(T2341019)NSFC-Guangdong Joint Fund(U1132001)+9 种基金General Program of the National Natural Science Foundation of China(82174243 and 82204948)Natural Science Foundation of Guangdong Province,China(2023A1515110757)Guangzhou Science and Technology Plan Project(2024B03J1343)Major Scientific and Technological Project of Guangzhou Municipal Health Commission(20252D003)Research Project of Traditional Chinese Medicine Bureau of Guangdong Province(20241208)General project of Beijing Natural Science Foundation(7242227)Fundamental Research Funds for the Central Universities(BZY-JMZY-2022-001 and 2023-JYB-JBZD-009)High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine(zyyzdxk-2023251)Major Science and Technology Special Projects in Hubei Province(2023BCA005)the Chief Scientist Research Project of Hubei Shizhen Laboratory(HSL2024SX0002).
文摘Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.
基金supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202006)the High-level traditional Chinese medicine key subject construction project of National Administration of Traditional Chinese Medicine-Evidence-based Traditional Chinese Medicine(ZYYZDXK-2023249).
文摘Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.
基金Supported by the National Natural Science Foundation of China(No.82074500)CACMS Innovation Fund(No.CI2021A02605)+1 种基金Administration of Traditional Chinese Medicine of Zhejiang Province(No.2024ZR029)Science and Technology Program of Wenzhou City(No.Y2023210).
文摘AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.
基金supported by the National Natural Science Foundation of China (Grant Nos.52304227 and 52104133)Scientific and Technological Research Platform for Disaster Prevention and Control of Deep Coal Mining (Anhui University of Science and Technology) (Grant No.DPDCM2208).
文摘To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.
基金“Cyborg Narratives and the Construction of 21^(st)Century Science Fiction Poetics”(22BZW175)sponsored by the National Social Science Fund of China。
文摘Joanna Page is Director of CRASSH and Professor of Latin American Studies at the University of Cambridge.Her research interests are generally connected to the relationship between science and culture in Latin America.She has also worked on questions of memory,modernity,capitalism,posthumanism,new materialism,decoloniality,ecology,and environmental thought.This interview covers three main aspects:the characteristics of science fiction texts in Latin America,the interdisciplinary research models at the intersection of science,literature,and art,and Latin America as a field of regional studies.Professor Page starts with Argentine science fiction novels and expands the discussion to include graphic novels in Latin America,outlining the panorama of science fiction and its indigenous features.The conversation delves into the literary and technological relationships within Latin American science fiction texts.Building upon this foundation,this interview explores the interdisciplinary research paradigms concerning the relationship between science and culture,aiming to contribute to regional studies by exploring new pathways for interdisciplinary,cross-regional,and trans-media research.
文摘Professor Paul Crosthwaite,from the School of Literature,Languages,and Cultures at the University of Edinburgh,is a prominent scholar in the interdisciplinary field of literature and economics.He is a co-editor of the Palgrave Studies in Literature,Culture,and Economics series and The Cambridge Companion to Literature and Economics(2022).In recent years,he has significantly influenced the intersection of literature and economics,advocating particularly for a shift towards the Economic Humanities.This interview covers:1.The definition and theoretical origin of the Economic Humanities;2.The internal heterogeneity and critical limitations of the New Economic Criticism,and the theoretical advantages and potential development of the Economic Humanities;3.What research paradigms do Environmental Humanities,Medical Humanities,and Digital Humanities provide for the Economic Humanities;4.How literary researchers can work at the interface of the Economic Humanities research.As a novel interdisciplinary interface between literature and economics,Professor Paul Crosthwaite’s concept of the Economic Humanities not only pioneers methodological tools for interdisciplinary studies of literature and economics but also underscores the interpretative potential and disciplinary benefits of literary viewpoints on economics.This underscores the vital role of literature in human knowledge,meriting attention from the literary research academia.
文摘Cohort studies are important epidemiological methods to investigate associations between environmental factors,individual characteristics,and disease or other health outcomes.As a paradigm of cohort studies,the Framingham Heart Study(FHS)is the longest-running cardiovascular epidemiological study,starting in 1948.
基金supported by the Ministry of Education Chunhui Program Collaborative Scientific Research Projects(Grant No.:HZKY20220286)Henan Province Foreign Experts Introduction Program(Grant No.:HNGD2022021)+1 种基金Natural Science Foundation of Henan Province(Grant No.:23230042151)the Foundation of the National Key Program of Research and Development of China(Grant No.:2016YFC0900803)。
文摘Rapid population aging has led to an increased focus on age-related conditions such as sarcopenia.causing loss of muscle mass and strength^([1,2]). Sarcopenia is associated with adverse outcomes,including falls, functional decline, frailty, and mortality, which can lower the quality of life and shorten lifespan^([1,2]).
基金funded by the National Key Research and Development Program of China(No.2024YFE0208100).
文摘The scroll expander,as the core component of the micro-compressed air energy storage and power generation system,directly affects the output efficiency of the system.Meanwhile,the scroll profile plays a central role in determining the output performance of the scroll expander.In this study,in order to investigate the output characteristics of a variable cross-section scroll expander,numerical simulation and experimental studies were con-ducted by using Computational Fluid Dynamics(CFD)methods and dynamic mesh techniques.The impact of critical parameters on the output performance of the scroll expander was analyzed through the utilization of the control variable method.It is found that increasing the inlet pressure and temperature within a certain range can improve the output power of the scroll expander.However,the increase in temperature and meshing clearance leads to a decline in the overall output performance of the scroll expander,leading to a decrease in volumetric efficiency by 8.43%and 12.79%,respectively.The experiments demonstrate that under equal inlet pressure conditions,increasing the inlet temperature elevates both the rotational speed and torque output of the scroll expander.Specifically,compared to operating at normal temperatures,the output torque increases by 21.8%under high-temperature conditions.However,the rate of speed and torque variation decreases as a consequence of enlarged meshing clearance,resulting in increased internal leakage and reduction in isentropic efficiency.
文摘BACKGROUND Depression is a significant risk factor for diabetes,particularly type 2 diabetes.However,depressive symptoms differ from clinical depression.Previous research has not fully considered the relationship between the trajectory of depressive symptoms and the risk of developing diabetes over time.AIM To investigate the association between depressive symptoms,their trajectories,and the risk of developing diabetes in two prospective cohort studies.METHODS In the first phase we analyzed the association between depressive symptoms and the risk of developing diabetes separately using the Health and Retirement Study(HRS).Depressive symptom trajectories were assessed by examining changes in depressive symptoms at baseline and again 8 years later.We then identified specific depressive symptom trajectories that increased the risk of diabetes in the second phase.Finally,we confirmed the association between depressive symptoms and their trajectories with diabetes risk using the English Longitudinal Study of Ageing(ELSA)as a validation study.Depressive symptom trajectories were categorized into five states based on changes in the modified 8-item Center for Epidemiological Studies-Depression scores:Persistently high;increasing;fluctuating;decreasing;and persistently low.Diabetes mellitus was defined as self-reported,physician-diagnosed diabetes.Cox proportional hazards models were used to assess hazard ratios(HR)and 95%confidence intervals(CI),adjusting for potential confounders.RESULTS In the first phase a total of 27658 participants were included(HRS:18633,ELSA:9025),among whom 6582 had depressive symptoms(HRS:4547,ELSA:2035),6407 had somatic depressive symptoms(HRS:4414,ELSA:1993),and 26415 had cognitive-affective depressive symptoms(HRS:17755,ELSA:8660).We found that overall depressive symptoms(HRS:HR=1.14,95%CI:1.07-1.22;ELSA:HR=1.18,95%CI:1.03-1.34)and somatic depressive symptoms(HRS:HR=1.14,95%CI:1.07-1.22;ELSA:HR=1.25,95%CI:1.10-1.42)increased the risk of diabetes,while cognitive depressive symptoms were not associated with diabetes risk.Over an 8-year follow-up we identified 19729 trajectories of overall,somatic,and cognitive-affective depressive symptoms(HRS:13918,ELSA:5811).In the second phase we found that persistently high(HRS:HR=1.22,95%CI:1.06-1.40,ELSA:HR=1.54,95%CI:1.16-2.05 in total and HRS:HR=1.24,95%CI:1.07-1.43,ELSA:HR=1.79,95%CI:1.36-2.35 in somatic)and fluctuating(HRS:HR=1.09,95%CI:1.01-1.17,ELSA:HR=1.33,95%CI:1.14-1.55 in total and HRS:HR=1.10,95%CI:1.02-1.18,ELSA:HR=1.31,95%CI:1.13-1.53 in somatic)trajectories of overall and somatic depressive symptoms increased the risk of diabetes,while increasing trajectories may also raise diabetes risk.However,decreasing trajectories were not associated with diabetes risk.Cognitive-affective depressive symptoms showed no association with diabetes risk regardless of trajectory changes.Sensitivity analyses confirmed the reliability of the findings.CONCLUSION Persistently high and fluctuating trajectories of overall and somatic depressive symptoms increased the risk of diabetes,while decreasing trajectories were not associated with diabetes risk.In contrast trajectories of cognitiveaffective depressive symptoms show no relationship with diabetes risk.Focusing on depressive symptom trajectories,particularly those of somatic depressive symptoms,represented a viable strategy for future diabetes prevention.
