Out-of-plane microneedle structures are widely used in various applications such as transcutaneous drug delivery and neural signal recording for brain machine interface.This work presents a novel but simple method to ...Out-of-plane microneedle structures are widely used in various applications such as transcutaneous drug delivery and neural signal recording for brain machine interface.This work presents a novel but simple method to fabricate high-density silicon(Si)microneedle arrays with various heights and diverse cross-sectional shapes depending on photomask pattern designs.The proposed fabrication method is composed of a single photolithography and two subsequent deep reactive ion etching(DRIE)steps.First,a photoresist layer was patterned on a Si substrate to define areas to be etched,which will eventually determine the final location and shape of each individual microneedle.Then,the 1st DRIE step created deep trenches with a highly anisotropic etching of the Si substrate.Subsequently,the photoresist was removed for more isotropic etching;the 2nd DRIE isolated and sharpened microneedles from the predefined trench structures.Depending on diverse photomask designs,the 2nd DRIE formed arrays of microneedles that have various height distributions,as well as diverse cross-sectional shapes across the substrate.With these simple steps,high-aspect ratio microneedles were created in the high density of up to 625 microneedles mm^(-2)on a Si wafer.Insertion tests showed a small force as low as~172μN/microneedle is required for microneedle arrays to penetrate the dura mater of a mouse brain.To demonstrate a feasibility of drug delivery application,we also implemented silk microneedle arrays using molding processes.The fabrication method of the present study is expected to be broadly applicable to create microneedle structures for drug delivery,neuroprosthetic devices,and so on.展开更多
Rolling process plays an important role in the manufacture of Bi-based high temperature superconductor tapes, and the plastic flow regularities of the superconducting wires during deformation will directly affect the ...Rolling process plays an important role in the manufacture of Bi-based high temperature superconductor tapes, and the plastic flow regularities of the superconducting wires during deformation will directly affect the ultimate quality of the tapes. In order to investigate the effect of cross-sectional shapes before fiat rolling on the performance and homogeneity of the tapes, some numerical models of Bi-2223/Ag wires with different cross-sectional shapes including circular, square, elliptical and racetrack cross-sections are constructed during the rolling process. By comparing the relative density, logarithmic strain ratio and length-width ratio on the filaments, it is revealed that Bi-2223/Ag wire with special-shaped cross-section can achieve better conductivity than the round wire, in particular, the racetrack cross-sectional wire has the second best performance among four wires. Based on material processability and experimental condition, tri-pass racetrack drawing technique is employed to optimize the process and obtain racetrack cross-sectional wire. The rolling process of Bi-2223/Ag wire with racetrack cross-section causes more intensive deformation of filaments in the center of the tape and achieves the filaments with larger length-width ratio. Also, the deformation distribution of filaments verifies the numerical results. Consequently, the racetrack drawing technique can be utilized for a reference during the mechanical processing and to increase the current transmission capacities of Bi-2223/Ag tapes.展开更多
In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional sha...In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional shapes, such as round or rectangle. The author reveals through geometric calculation of the duct cross-sectional shapes and engineering experiences that the round cross-section is an optimal shape in the duct system. The round duct has the shorter perimeter than the other cross-sectional shape ducts and the stronger structure in the same working condition. The material saving of the round duct due to the shorter perimeter is quantitatively determined. In the pater, it is shown that the round duct is economically attractive. The economic analysis for the material cost saving is illustrated by an example. For a long duct system, the material and material cost savings are significant. It is suggested that the round duct in the gas and air duct system should have priority as long as the field conditions are allowed. In the paper, the material cost saving is also converted to PW, AW, and FW used for LCC economic analysis.展开更多
The heat transfer of hydrocarbon refrigerant across tube bundles have been widely used in refrigeration.Three-dimensional simulation model using volume of fluid(VOF) was presented to study the effects of tube shapes o...The heat transfer of hydrocarbon refrigerant across tube bundles have been widely used in refrigeration.Three-dimensional simulation model using volume of fluid(VOF) was presented to study the effects of tube shapes on flow pattern, film thickness and heat transfer of n-pentane across tube bundles, including circle, ellipse-shaped, egg-shaped and cam-shaped tube bundles. Simulation results agree well with experimental data in the literature. The liquid film thickness of sheet flow and heat transfer for different tube shapes were obtained numerically. The flow pattern transition occurs lower vapor quality for ellipse-shaped tube than other tube shapes. For sheet flow, the liquid film on circle tube and ellipseshaped tube is symmetrically distributed along the circumferential direction. However, the liquid film on egg-shaped tube at circumferential angles(θ) = 15°–60° is thicker than θ = 135°–165°. The liquid film on cam tube at θ = 15°–60° is slightly thinner than θ = 135°–165°. The liquid film thickness varies from thinner to thicker for ellipse-shaped, cam-shaped, egg-shape and circle within θ = 15°–60°. The effect of tube shape is insignificant on thin liquid film thickness. Ellipse-shaped tube has largest heat transfer coefficient for sheet flow. In practical engineering, the tube shape could be designed as ellipse to promote heat transfer.展开更多
Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Fa...Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.展开更多
To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with...To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.展开更多
Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between ...Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.展开更多
The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly comple...The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.展开更多
Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess...Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.展开更多
OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which...OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.展开更多
BACKGROUND As an antioxidant,serum superoxide dismutase(SOD)have been found to be associated with hypertension.METHODS The data were derived from the Chinese Longitudinal Healthy Longevity Survey(CLHLS),a prospective ...BACKGROUND As an antioxidant,serum superoxide dismutase(SOD)have been found to be associated with hypertension.METHODS The data were derived from the Chinese Longitudinal Healthy Longevity Survey(CLHLS),a prospective cohort study in China.We explored the association between serum SOD and blood pressure(BP)using multivariable correction analysis in an older Chinese population.RESULTS We observed a significantly gradual downward trend in the association between serum SOD levels and diastolic BP(DBP)in participants with lower serum SOD levels(<58 IU/mL),while no associations were observed between serum SOD levels and DBP in participants with higher serum SOD levels(>58 IU/mL).Similar results showed a significant gradual downward trend in associations between serum SOD levels and the risk of diastolic hypertension only at SOD<58 IU/mL.Multiple linear regression analysis suggested that serum SOD was negatively correlated with DBP(Sβ=-0.088,P<0.001)but not with SBP(Sβ=0.013,P=0.607).Multiple logistic regression analysis suggested that serum SOD was independently associated with the risk of diastolic hypertension(OR=0.984,95%CI:0.973−0.996,P=0.010)but not with the risk of systolic hypertension(OR=1.001,95%CI:0.990−1.012,P=0.836))after adjusting for relevant confounding factors.Serum SOD levels(<58 IU/mL,>58 IU/mL)were an effect modifier of the association between serum SOD and DBP(interaction P=0.0038)or the risk of diastolic hypertension(interaction P=0.0050).CONCLUSIONS Our study indicated for the first time that there was an L-shaped association between serum SOD levels and the risk of diastolic hypertension in the older Chinese population.展开更多
Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a kno...Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.展开更多
Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods...Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.展开更多
association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a ...association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a cross-sectional study in a hospital-based nursing school.EI level was measured using the Schutte Self-report Emotional Intelligence Scale(SSEIS).Results:We recruited 287 participants(mean age:21.9 years).Their mean SSEIS score was 119.6(95%CI=118.57-120.65).The mean SSEIS scores of 172 full-time and 115 part-time nurses were 120.7(95%CI=119.3-122.0)and 118.1(95%CI=116.5-119.6),respectively.There was no significant difference between the groups.Conclusion:The EI difference between full-time and part-time nursing students was statistically insignificant.The need for further EI development among both full-time and part-time students must be addressed.展开更多
Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2...Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.展开更多
Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12...Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.展开更多
The downstream region of the Yangtze River in China experiences tidal influences, with most tributary inlets regulated by hydraulic hubs that control water diversion and drainage. The cross-sectional characteristics o...The downstream region of the Yangtze River in China experiences tidal influences, with most tributary inlets regulated by hydraulic hubs that control water diversion and drainage. The cross-sectional characteristics of these rivers under intermittent diversion and drainage remain uncertain due to various boundary conditions, including tidal fluctuations from the Yangtze River, hydraulic hub operations, and tributary water levels. This study examines the Yanglintang River as a case study, utilizing a two-dimensional water-sediment numerical model to analyze the response of river cross-sections under varying diversion-to-drainage ratios. The findings demonstrate that river cross-sections transform from a regular trapezoidal shape to a pot-bottom configuration, achieving equilibrium within 2 to 3 years under the influence of water diversion and drainage. The operational duration of water diversion and drainage shows minimal impact on river cross-sectional morphology, with bed scouring reaching approximately 10 cm when the operational duration doubles. However, the flow rate of water diversion-drainage operations emerges as the primary factor controlling river cross-sectional morphology, resulting in bed scouring magnitude of approximately 1 m under doubled flow rate conditions.展开更多
This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are ob...This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are obtained.Pore structures are segmented by the U-shaped network(U-Net)neural network integrated with the Canny edge detection operator,ensuring accurate pore delineation and edge extraction.The trained U-Net achieves 98.55%accuracy.The 2D data are superimposed and processed into 3D point clouds,enabling reconstruction of the pore structure and aluminum skeleton.Analysis of pore 01 shows the cross-sectional area initially increases,and then decreases with milling depth,with a uniform point distribution of 40 per layer.The reconstructed model exhibits a porosity of 77.5%,with section overlap rates between the 2D pore segmentation and the reconstructed model exceeding 96%,confirming high fidelity.Equivalent sphere diameters decrease with size,averaging 1.95 mm.Compression simulations reveal that the stress-strain curve of the 3D reconstruction model of aluminum foam exhibits fluctuations,and the stresses in the reconstruction model concentrate on thin cell walls,leading to localized deformations.This method accurately restores the aluminum foam’s complex internal structure,improving reconstruction preci-sion and simulation reliability.The approach offers a cost-efficient,high-precision technique for optimizing material performance in engineering applications.展开更多
BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of...BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of the pharyngeal airway during sleep;however,the relationship between these two conditions remains unexplored.We hypothesized that a higher TyG-BMI is associated with the occurrence of OSA.AIM To assess the association between TyG-BMI and OSA in adults in the United States.METHODS A cross-sectional study was conducted utilizing data from the National Health and Nutrition Examination Surveys spanning from 2005-2008 to 2015-2018.TyGBMI was calculated as Ln[triglyceride(mg/dL)×fasting blood glucose(mg/dL)/2]×BMI.Restricted cubic splines were used to analyze the risk of TyG-BMI and OSA occurrence.To identify potential nonlinear relationships,we combined Cox proportional hazard regression with smooth curve fitting.We also conducted sensitivity and subgroup analyses to verify the robustness of our findings.RESULTS We included 16794 participants in the final analysis.Multivariate regression analysis showed that participants with a higher TyG-BMI had a higher OSA incidence.After adjusting for all covariates,TyG-BMI was positively correlated with the prevalence of OSA(odds ratio:1.28;95%confidence interval:1.17,1.40;P<0.001);no significant nonlinear relationship was observed.Subgroup analysis showed no strong correlation between TyG-BMI and OSA in patients with diabetes.The correlation between TyG-BMI and OSA was influenced by age,sex,smoking status,marital status,hypertensive stratification,and obesity;these subgroups played a moderating role between TyGBMI and OSA.Even after adjusting for all covariates,there was a positive association between TYG-BMI and OSA prevalence.CONCLUSION A higher TyG-BMI index is linked to higher chances of developing OSA.As TyG-BMI is an indicator of IR,managing IR may help reduce the risk of OSA.展开更多
AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National ...AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.展开更多
基金This work was supported by KIST(Korea Institute of Science and Technology)institutional grants(2E30965,and 2V07360)the National R&D Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science and ICT(Nos.2020R1C1C1006065,2021M3F3A2A01037366)+1 种基金This work was also supported by the Korea Medical Device Development Fund grant funded by the Korea government(the Ministry of Science and ICT,the Ministry of Trade,Industry and Energy,the Ministry of Health&Welfarethe Ministry of Food and Drug Safety)(Project Number:9991006818,KMDF_PR_20200901_0145-2021).
文摘Out-of-plane microneedle structures are widely used in various applications such as transcutaneous drug delivery and neural signal recording for brain machine interface.This work presents a novel but simple method to fabricate high-density silicon(Si)microneedle arrays with various heights and diverse cross-sectional shapes depending on photomask pattern designs.The proposed fabrication method is composed of a single photolithography and two subsequent deep reactive ion etching(DRIE)steps.First,a photoresist layer was patterned on a Si substrate to define areas to be etched,which will eventually determine the final location and shape of each individual microneedle.Then,the 1st DRIE step created deep trenches with a highly anisotropic etching of the Si substrate.Subsequently,the photoresist was removed for more isotropic etching;the 2nd DRIE isolated and sharpened microneedles from the predefined trench structures.Depending on diverse photomask designs,the 2nd DRIE formed arrays of microneedles that have various height distributions,as well as diverse cross-sectional shapes across the substrate.With these simple steps,high-aspect ratio microneedles were created in the high density of up to 625 microneedles mm^(-2)on a Si wafer.Insertion tests showed a small force as low as~172μN/microneedle is required for microneedle arrays to penetrate the dura mater of a mouse brain.To demonstrate a feasibility of drug delivery application,we also implemented silk microneedle arrays using molding processes.The fabrication method of the present study is expected to be broadly applicable to create microneedle structures for drug delivery,neuroprosthetic devices,and so on.
基金supported by Major Program of National Natural Science Foundation of China (Grant No. 50635050)National Natural Science Foundation of China (Grant No. 50575124)
文摘Rolling process plays an important role in the manufacture of Bi-based high temperature superconductor tapes, and the plastic flow regularities of the superconducting wires during deformation will directly affect the ultimate quality of the tapes. In order to investigate the effect of cross-sectional shapes before fiat rolling on the performance and homogeneity of the tapes, some numerical models of Bi-2223/Ag wires with different cross-sectional shapes including circular, square, elliptical and racetrack cross-sections are constructed during the rolling process. By comparing the relative density, logarithmic strain ratio and length-width ratio on the filaments, it is revealed that Bi-2223/Ag wire with special-shaped cross-section can achieve better conductivity than the round wire, in particular, the racetrack cross-sectional wire has the second best performance among four wires. Based on material processability and experimental condition, tri-pass racetrack drawing technique is employed to optimize the process and obtain racetrack cross-sectional wire. The rolling process of Bi-2223/Ag wire with racetrack cross-section causes more intensive deformation of filaments in the center of the tape and achieves the filaments with larger length-width ratio. Also, the deformation distribution of filaments verifies the numerical results. Consequently, the racetrack drawing technique can be utilized for a reference during the mechanical processing and to increase the current transmission capacities of Bi-2223/Ag tapes.
文摘In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional shapes, such as round or rectangle. The author reveals through geometric calculation of the duct cross-sectional shapes and engineering experiences that the round cross-section is an optimal shape in the duct system. The round duct has the shorter perimeter than the other cross-sectional shape ducts and the stronger structure in the same working condition. The material saving of the round duct due to the shorter perimeter is quantitatively determined. In the pater, it is shown that the round duct is economically attractive. The economic analysis for the material cost saving is illustrated by an example. For a long duct system, the material and material cost savings are significant. It is suggested that the round duct in the gas and air duct system should have priority as long as the field conditions are allowed. In the paper, the material cost saving is also converted to PW, AW, and FW used for LCC economic analysis.
基金supported by National Natural Science Foundation of China (52006242)National Natural Science Foundation of China (52192623)+1 种基金Science Foundation of China University of Petroleum,Beijing (ZX20200126)Science and technology program for strategic cooperation of CNPC–China University of Petroleum (ZLZX2020-05)。
文摘The heat transfer of hydrocarbon refrigerant across tube bundles have been widely used in refrigeration.Three-dimensional simulation model using volume of fluid(VOF) was presented to study the effects of tube shapes on flow pattern, film thickness and heat transfer of n-pentane across tube bundles, including circle, ellipse-shaped, egg-shaped and cam-shaped tube bundles. Simulation results agree well with experimental data in the literature. The liquid film thickness of sheet flow and heat transfer for different tube shapes were obtained numerically. The flow pattern transition occurs lower vapor quality for ellipse-shaped tube than other tube shapes. For sheet flow, the liquid film on circle tube and ellipseshaped tube is symmetrically distributed along the circumferential direction. However, the liquid film on egg-shaped tube at circumferential angles(θ) = 15°–60° is thicker than θ = 135°–165°. The liquid film on cam tube at θ = 15°–60° is slightly thinner than θ = 135°–165°. The liquid film thickness varies from thinner to thicker for ellipse-shaped, cam-shaped, egg-shape and circle within θ = 15°–60°. The effect of tube shape is insignificant on thin liquid film thickness. Ellipse-shaped tube has largest heat transfer coefficient for sheet flow. In practical engineering, the tube shape could be designed as ellipse to promote heat transfer.
基金supported by the National Natural Science Foundation of China(82341245,82371491)the Chinese Central Government(Key Project of Public Health Program)the National Key Research and Development Program of China(2018YFC1311706,2018YFC1311702)。
文摘Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.
基金supported by the National Natural Science Foundation of China (Grant Nos.52304227 and 52104133)Scientific and Technological Research Platform for Disaster Prevention and Control of Deep Coal Mining (Anhui University of Science and Technology) (Grant No.DPDCM2208).
文摘To investigate the effects of the maximum principal stress direction(θ)and cross-section shape on the failure characteristics of sandstone,true-triaxial compression experiments were conducted using cubic samples with rectangular,circular,and D-shaped holes.Asθincreases from 0°to 60°in the rectangular hole,the left failure location shifts from the left corner to the left sidewall,the left corner,and then the floor,while the right failure location shifts from the right corner to the right sidewall,right roof corner,and then the roof.Furthermore,the initial failure vertical stress first decreases and then increases.In comparison,the failure severity in the rectangular hole decreases for variousθvalues as 30°>45°>60°>0°.With increasingθ,the fractal dimension(D)of rock slices first increases and then decreases.For the rectangular and D-shaped holes,whenθ=0°,30°,and 90°,D for the rectangular hole is less than that of the D-shaped hole.Whenθ=45°and 60°,D for the rectangular hole is greater than that of the D-shaped hole.Theoretical analysis indicates that the stress concentration at the rectangular and D-shaped corners is greater than the other areas.The failure location rotates with the rotation ofθ,and the failure occurs on the side with a high concentration of compressive stress,while the side with the tensile and compressive stresses remains relatively stable.Therefore,the fundamental reason for the rotation of failure location is the rotation of stress concentration,and the external influencing factor is the rotation ofθ.
文摘Objective The relationship between non-high-density lipoprotein(NHDL)cholesterol to high-density lipoprotein cholesterol(HDL-C)ratio(NHHR)and stoke remains unknown.This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America(USA).Methods To clarify the relationship between the NHHR and stroke risk,this study used a multivariable logistic regression model and a restricted cubic spline(RCS)model to investigate the association between the NHHR and stroke,and data from the National Health and Nutrition Examination Survey(NHANES)from 2005 to 2018.Subgroup and sensitivity analyses were conducted to test the robustness of the results.Results This study included 29,928 adult participants,of which 1,165 participants had a history of stroke.Logistic regression analysis of variables demonstrated a positive association between NHHR and stroke(OR 1.24,95%CI:1.03-1.50,P=0.026).Compared with the lowest reference group of NHHR,participants in the second,third,and fourth quartile had a significantly increased risk of stroke after full adjustments(OR:1.35,95%CI:1.08-1.69)(OR:1.83,95%CI:1.42-2.36)(OR:2.04,95%CI:1.50-2.79).In the total population,a nonlinear dose-response relationship was observed between the NHHR and stroke risk(P non-linearity=0.002).This association remained significant in several subgroup analyses.Further investigation of the NHHR may enhance our understanding of stroke prevention and treatment.Conclusion Our findings suggest a positive correlation between the NHHR and an increased prevalence of stroke,potentially serving as a novel predictive factor for stroke.Timely intervention and management of the NHHR may effectively mitigate stroke occurrence.Prospective studies are required to validate this association and further explore the underlying biological mechanisms.
基金financially supported by Guangdong Province Basic and Applied Basic Research Fund Project(Grant No.2022B1515250009)Liaoning Provincial Natural Science Foundation-Doctoral Research Start-up Fund Project(Grant No.2024-BSBA-05)+1 种基金Major Science and Technology Innovation Project in Shandong Province(Grant No.2024CXGC010803)the National Natural Science Foundation of China(Grant Nos.52271269 and 12302147).
文摘The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections.
基金supported by an Innovation Fund for Medical Sciences of the Chinese Academy of Medical Sciences (Grant No.2019-I2M-2-007).
文摘Objective:Postpartum nutrition plays a critical role in maternal recovery and long-term health.However,the nutritional status of working mothers in the postpartum period remains understudied.This study aimed to assess the dietary quality of postpartum women in urban Beijing,identify occupational-related factors influencing their diet,and explore potential interventions to improve maternal nutrition during the postpartum period.Methods:In this cross-sectional analysis,554 women one year after delivery were recruited from ten community health centers.Sociodemographic,occupational and postpartum care variables were collected via questionnaire.Dietary intake over the preceding year was assessed using a food frequency questionnaire.The modified dietary balance index for postpartum women were used for dietary quality assessment.Results:The study revealed severe dietary imbalances among postpartum women,characterized by excessive consumption of cereals,eggs,and meats,while their intake of vegetables,fruits,and dairy products was inadequate.According to dietary balance index for postpartum women,66.25%of mothers showed varying degrees of excessive intake.45.31%of mothers experienced varying levels of insufficient intake,with only 19.86%of participants having a relatively balanced diet.Occupational differences were observed,with women in the commercial employment group showing higher levels of excessive food intake.The analysis of influencing factors showed that family monthly income,maternity leave,and postpartum care significantly affected the dietary quality.Conclusions:Postpartum women in Beijing experience widespread dietary imbalances,with both excesses and deficiencies.Occupational context and related factors significantly shape diet quality.These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.
基金National Nonprofit Institute Research Grant for the Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences:Mechanism of Regulating Phlegm-Dampness Constitution to Prevent Metabolic Diseases based on Gut Microbiota-host DNA Methylation(No.YZ-202151)。
文摘OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which included 249 participants with damp-heat constitution or balanced constitution.Baseline information of participants was collected,and stool samples were collected for gut microbiota analysis.Principal coordinate analysis,linear discriminant analysis effect size analysis,receiver operating characteristic,random forest model,and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.RESULTS:Compared to those in the BC group,the richness and diversity of the microbiota,specifically those of several short-chain fatty acid producing genera such as Barnesiella,Coprobacter,and Butyricimonas,were significantly decreased in the DHC group.Regarding biological functions,flavonoid biosynthesis,propanoate metabolism,and nucleotide sugar metabolism were suppressed,while arachidonic acid metabolism and glutathione metabolism were enriched in the DHC group.Finally,a classifier based on the microbiota was constructed to discriminate between the DHC and BC populations.CONCLUSION:The gut microbiota of the DHC population exhibits significantly reduced diversity and is closely related to inflammation,metabolic disorders,and liver steatosis,which is consistent with clinical observations,thus serving as a potential diagnostic tool for traditional Chinese medicine constitution discrimination.
基金supported by grants from the National Natural Science Foundation of China(NSFC 81860070 and 82070350)JiangXi Province Science Foundation for Distinguished Young Scholar(20202ACBL216001)Jiangxi Province’s Main Discipline Academic and Technical Leader Training Program-Leading Talent Project(20204BCJ22029).
文摘BACKGROUND As an antioxidant,serum superoxide dismutase(SOD)have been found to be associated with hypertension.METHODS The data were derived from the Chinese Longitudinal Healthy Longevity Survey(CLHLS),a prospective cohort study in China.We explored the association between serum SOD and blood pressure(BP)using multivariable correction analysis in an older Chinese population.RESULTS We observed a significantly gradual downward trend in the association between serum SOD levels and diastolic BP(DBP)in participants with lower serum SOD levels(<58 IU/mL),while no associations were observed between serum SOD levels and DBP in participants with higher serum SOD levels(>58 IU/mL).Similar results showed a significant gradual downward trend in associations between serum SOD levels and the risk of diastolic hypertension only at SOD<58 IU/mL.Multiple linear regression analysis suggested that serum SOD was negatively correlated with DBP(Sβ=-0.088,P<0.001)but not with SBP(Sβ=0.013,P=0.607).Multiple logistic regression analysis suggested that serum SOD was independently associated with the risk of diastolic hypertension(OR=0.984,95%CI:0.973−0.996,P=0.010)but not with the risk of systolic hypertension(OR=1.001,95%CI:0.990−1.012,P=0.836))after adjusting for relevant confounding factors.Serum SOD levels(<58 IU/mL,>58 IU/mL)were an effect modifier of the association between serum SOD and DBP(interaction P=0.0038)or the risk of diastolic hypertension(interaction P=0.0050).CONCLUSIONS Our study indicated for the first time that there was an L-shaped association between serum SOD levels and the risk of diastolic hypertension in the older Chinese population.
基金supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202006)the High-level traditional Chinese medicine key subject construction project of National Administration of Traditional Chinese Medicine-Evidence-based Traditional Chinese Medicine(ZYYZDXK-2023249).
文摘Background:The bibliometrics of acupuncture are growing rapidly.However,the absence of reporting guidelines may lead to significant duplication and waste,thereby undermining the research’s value.To address this,a knowledge mapping was generated based on published studies to investigate the characteristics of bibliometric studies on acupuncture and the extent of duplicate publications,with the overarching goal of providing a comprehensive overview of the knowledge structure in this field.Methods:This cross-sectional study used three databases(PubMed,Web of Science,and Scopus)to identify relevant studies up to May 1,2024.In addition,the reference lists were retrieved as a supplement.To track research trends,we employed Microsoft Excel and R software to extract,code,and analyze information.Study selection,data extraction,and validation were performed independently by at least two reviewers.The reporting quality of included studies was assessed using the Preliminary guideline for reporting bibliometric reviews of the biomedical literature(BIBLIO).Results:Among the 6,221 bibliometric reviews examined,113 relevant publications were identified,80 focusing on various diseases/conditions.The annual number of publications has gradually increased,with the output in the past four years being 3.52 times higher than that before 2020.China(106)and Chengdu University of Traditional Chinese Medicine(16)have the highest number of publications.The most prolific author is Fan-Rong Liang,with six articles.The first bibliometric study,by Hai-Yan Li,was published in 2010.Journal of Pain Research,with 36 articles,holds the most publications.The top three diseases:diseases of the nervous system;symptoms,signs,or clinical findings not elsewhere classified;and mental,behavioral,or neurodevelopmental disorders.There may be potential duplication in research on 13 diseases/conditions,notably stroke,migraine,pain/analgesia,cancer pain,shoulder pain,facial paralysis/bell’s palsy,chronic pain,and cognitive impairment.In BIBLIO,the most frequently missing items are issues/topics(item 2),quality assessment(item 11),and descriptive findings(item 13).Conclusion:This study demonstrates that acupuncture bibliometrics is actively utilized to identify dominant diseases/conditions,aiding scholars in understand the knowledge structure and main topics.Although the number of related studies is increasing,with an average of 25 studies annually,overlap in some areas highlights the need for adherence to reporting guidelines and careful topic selection to ensure truly valuable insights and knowledge contributions.The adherence to BIBLIO’s 20 proposed items across analyzed articles,highlighting important in reporting practices.
基金funded by Tianjin Key Medical Discipline(Specialty)Construction Project,China(Grant No.TJYXZDXK-011A)Tianjin Medical University Cancer Institute&Hospital Nursing Special Fund Project(H2304)。
文摘Objectives:This study aimed to classify young breast cancer patients into distinct ambivalence over emotional expression and to explore the factors influencingthe level of ambivalence over emotional expression.Methods:A total of 217 young breast cancer patients were enrolled from a tertiary Grade A oncology hospital in Tianjin,China,using the convenience sampling method.All participants completed the general questionnaire,Ambivalence over Emotion Expression Questionnaire(AEQ),and Family Adapt-Ability and Cohesion Evaluation Scales-Chinese Version(FACES-CV).We employed exploratory latent profileanalysis for ambivalence over emotional expression profilingand logistic regression analysis to identify the influentialfactors Results:The results of the latent profileanalysis supported the models of four latent profiles,which were definedas“low conflict-lowexpression reflection”(19.2%),“high conflict-high inhibition expression”(43.9%),“moderate conflict-highregret expression”(18.1%),and“moderate conflict-desire understand”(18.8%).Logistic regression revealed that family cohesion,marital status,residence,per capita monthly income,and cancer stage were the influencingfactors of ambivalence over emotional expression in young breast cancer patients(P<0.05)Conclusions:Levels of ambivalence over emotional expression ameast cancer patients with breast cancer were highly heterogeneous.Medical staff should provide psychological counseling and health education tailored to the unique characteristics of emotional expression ambivalence in different patient groups to promote healthy emotional expression among patients.
文摘association with academic and clinical performance.This study aimed to determine the EI level of hospital-based nursing students and examine differences between full-time and part-time students.Methods:We conducted a cross-sectional study in a hospital-based nursing school.EI level was measured using the Schutte Self-report Emotional Intelligence Scale(SSEIS).Results:We recruited 287 participants(mean age:21.9 years).Their mean SSEIS score was 119.6(95%CI=118.57-120.65).The mean SSEIS scores of 172 full-time and 115 part-time nurses were 120.7(95%CI=119.3-122.0)and 118.1(95%CI=116.5-119.6),respectively.There was no significant difference between the groups.Conclusion:The EI difference between full-time and part-time nursing students was statistically insignificant.The need for further EI development among both full-time and part-time students must be addressed.
文摘Objective:This study aimed to examine the association between parent-child relationships and physically aggressive behavior among adolescents.Methods:This is a cross-sectional study that uses secondary data from the 2015 Indonesia Global School-Based Health Survey(IGSHS).Health surveys were conducted in 75 schools representing three regions(Sumatra,Java-Bali;Outer Sumatra;and Java-Bali)in 26 provinces and 68 districts/cities in Indonesia(N=10,139 students).Students who participated were aged 12-19 years,were enrolled in public schools in the junior and high school levels.Results:It has been seen that for most middle-aged adolescents(58.7%),their parents(25%-29%)pay less attention to academic assignments(homework),problems,and use of free time.The most significant factors that influence adolescents to commit violence are smoking and consuming alcohol.Adolescents who smoke are twice as likely to commit physical violence compared with adolescents who do not smoke(OR=2.005;95%CI=1.7062-2.396).Meanwhile,adolescents who consume alcohol are 1.8 times more likely to commit physical violence compared with adolescents who do not consume alcohol(OR=1.807;95%CI=1.421-2.298).Conclusions:Through educational activities and consultations,this study’s findings are valuable for establishing parenting programs among those concerned about their children’s aggressive behavior.Meanwhile,counseling programs can be started in schools by conducting self-detection of negative adolescent behavior,such as screening for smoking,alcohol consumption,sleep issues,and attempted suicide.
基金supported by the National Natural Science Foundation of China(T2341019)NSFC-Guangdong Joint Fund(U1132001)+9 种基金General Program of the National Natural Science Foundation of China(82174243 and 82204948)Natural Science Foundation of Guangdong Province,China(2023A1515110757)Guangzhou Science and Technology Plan Project(2024B03J1343)Major Scientific and Technological Project of Guangzhou Municipal Health Commission(20252D003)Research Project of Traditional Chinese Medicine Bureau of Guangdong Province(20241208)General project of Beijing Natural Science Foundation(7242227)Fundamental Research Funds for the Central Universities(BZY-JMZY-2022-001 and 2023-JYB-JBZD-009)High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine(zyyzdxk-2023251)Major Science and Technology Special Projects in Hubei Province(2023BCA005)the Chief Scientist Research Project of Hubei Shizhen Laboratory(HSL2024SX0002).
文摘Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.
基金financially supported by the National Key Research and Development Program of China (Grant No.2023YFC3208604)Jiangsu Province Water Conservancy Science and Technology Project (Grant No.2023052)the National Natural Science Foundation of China (Grant No.51509168)。
文摘The downstream region of the Yangtze River in China experiences tidal influences, with most tributary inlets regulated by hydraulic hubs that control water diversion and drainage. The cross-sectional characteristics of these rivers under intermittent diversion and drainage remain uncertain due to various boundary conditions, including tidal fluctuations from the Yangtze River, hydraulic hub operations, and tributary water levels. This study examines the Yanglintang River as a case study, utilizing a two-dimensional water-sediment numerical model to analyze the response of river cross-sections under varying diversion-to-drainage ratios. The findings demonstrate that river cross-sections transform from a regular trapezoidal shape to a pot-bottom configuration, achieving equilibrium within 2 to 3 years under the influence of water diversion and drainage. The operational duration of water diversion and drainage shows minimal impact on river cross-sectional morphology, with bed scouring reaching approximately 10 cm when the operational duration doubles. However, the flow rate of water diversion-drainage operations emerges as the primary factor controlling river cross-sectional morphology, resulting in bed scouring magnitude of approximately 1 m under doubled flow rate conditions.
基金supported by the Key Research and DevelopmentPlan in Shanxi Province of China(No.201803D421045)the Natural Science Foundation of Shanxi Province(No.2021-0302-123104)。
文摘This study introduces a novel method for reconstructing the 3D model of aluminum foam using cross-sectional sequence images.Combining precision milling and image acquisition,high-qual-ity cross-sectional images are obtained.Pore structures are segmented by the U-shaped network(U-Net)neural network integrated with the Canny edge detection operator,ensuring accurate pore delineation and edge extraction.The trained U-Net achieves 98.55%accuracy.The 2D data are superimposed and processed into 3D point clouds,enabling reconstruction of the pore structure and aluminum skeleton.Analysis of pore 01 shows the cross-sectional area initially increases,and then decreases with milling depth,with a uniform point distribution of 40 per layer.The reconstructed model exhibits a porosity of 77.5%,with section overlap rates between the 2D pore segmentation and the reconstructed model exceeding 96%,confirming high fidelity.Equivalent sphere diameters decrease with size,averaging 1.95 mm.Compression simulations reveal that the stress-strain curve of the 3D reconstruction model of aluminum foam exhibits fluctuations,and the stresses in the reconstruction model concentrate on thin cell walls,leading to localized deformations.This method accurately restores the aluminum foam’s complex internal structure,improving reconstruction preci-sion and simulation reliability.The approach offers a cost-efficient,high-precision technique for optimizing material performance in engineering applications.
基金Supported by Sanming Project of Medicine in Shenzhen,No.SZZYSM202202010。
文摘BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of the pharyngeal airway during sleep;however,the relationship between these two conditions remains unexplored.We hypothesized that a higher TyG-BMI is associated with the occurrence of OSA.AIM To assess the association between TyG-BMI and OSA in adults in the United States.METHODS A cross-sectional study was conducted utilizing data from the National Health and Nutrition Examination Surveys spanning from 2005-2008 to 2015-2018.TyGBMI was calculated as Ln[triglyceride(mg/dL)×fasting blood glucose(mg/dL)/2]×BMI.Restricted cubic splines were used to analyze the risk of TyG-BMI and OSA occurrence.To identify potential nonlinear relationships,we combined Cox proportional hazard regression with smooth curve fitting.We also conducted sensitivity and subgroup analyses to verify the robustness of our findings.RESULTS We included 16794 participants in the final analysis.Multivariate regression analysis showed that participants with a higher TyG-BMI had a higher OSA incidence.After adjusting for all covariates,TyG-BMI was positively correlated with the prevalence of OSA(odds ratio:1.28;95%confidence interval:1.17,1.40;P<0.001);no significant nonlinear relationship was observed.Subgroup analysis showed no strong correlation between TyG-BMI and OSA in patients with diabetes.The correlation between TyG-BMI and OSA was influenced by age,sex,smoking status,marital status,hypertensive stratification,and obesity;these subgroups played a moderating role between TyGBMI and OSA.Even after adjusting for all covariates,there was a positive association between TYG-BMI and OSA prevalence.CONCLUSION A higher TyG-BMI index is linked to higher chances of developing OSA.As TyG-BMI is an indicator of IR,managing IR may help reduce the risk of OSA.
基金Supported by the National Natural Science Foundation of China(No.82074500)CACMS Innovation Fund(No.CI2021A02605)+1 种基金Administration of Traditional Chinese Medicine of Zhejiang Province(No.2024ZR029)Science and Technology Program of Wenzhou City(No.Y2023210).
文摘AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.
