We have found recently that two-step intrinsic hydroxyl radical(·OH)-dependent chemiluminescence(CL)could be produced by carcinogenic tetrahaloquinone and H_(2)O_(2).However,the first-step CL was too fast to clea...We have found recently that two-step intrinsic hydroxyl radical(·OH)-dependent chemiluminescence(CL)could be produced by carcinogenic tetrahaloquinone and H_(2)O_(2).However,the first-step CL was too fast to clearly detect the stepwise generation of·OH and CL,and to distinguish the exact dividing point between the first-step and second-step CL.Here we found that,extremely clear two-step intrinsic CL could be produced by the relative slow reaction of tetrabromohydroquinone(TBHQ)with H_(2)O_(2),which was directly dependent on the two-step·OH generation.Interestingly,the second-step,but not the first-step CL production of TBHQ/H_(2)O_(2)(CRET donor)was markedly enhanced by fluorescein(a typical xanthene dye,CRET acceptor)through a unique chemiluminescence resonance energy transfer(CRET)process.The novel CRET system of TBHQ/H_(2)O_(2)/fluorescein was successfully applied for the sensitive detection of TBHQ with the detection limit as low as 2.5μmol/L.These findings will help to develop more sensitive and highly efficient CL or CRET systems and specific CL sensor to detect the carcinogenic haloquinones,which may have broad environmental applications.展开更多
Electrophysical devices based on diathermy are one of the modalities used by many professionals to treat pain. The objective of this study was to identify the effects of Tecartherapy on healthy and unhealthy tissues. ...Electrophysical devices based on diathermy are one of the modalities used by many professionals to treat pain. The objective of this study was to identify the effects of Tecartherapy on healthy and unhealthy tissues. A systematic review of Tecartherapy technology was carried out. Articles published up to the year 2023 were investigated. The search argument used was “Capacitive-resistive electrical transfer” OR “Tecar” OR “Therapy Tecar” OR “CRET” in the BVS, Cochrane, PEDro, PubMed, IEEE Explore databases, Scielo and Web of Science. As for the main results of using Tecartherapy, there is an increase in temperature. In healthy tissues there is an increase in local blood flow, a decrease in muscle fatigue and an increase in muscle flexibility. In addition to the effects observed on healthy tissues, pain reduction and improved joint function were also observed. It was concluded that this technology has similar effects to other diathermy, but Tecartherapy proved to be safer and more comfortable. .展开更多
Nitrogen-doped carbon quantum dots(N-CQDs),synthesized via the rapid pyrolysis of ammonium citrate dibasic and ethylenediamine dihydrochloride,demonstrate remarkable chemiluminescence capabilities,emitting a vibrant b...Nitrogen-doped carbon quantum dots(N-CQDs),synthesized via the rapid pyrolysis of ammonium citrate dibasic and ethylenediamine dihydrochloride,demonstrate remarkable chemiluminescence capabilities,emitting a vibrant blue-green light in peroxyoxalate chemiluminescence(PO-CL)reactions.Among these,a distinct variant of N-CQDs is an exceptionally sensitive biosensor,facilitating the swift detection of copper ions(Cu^(2+))within human plasma and urine samples.Upon rapid binding of N-CQDs and Cu^(2+),non-emissive complex forms due to intra-chemiluminescence resonance energy transfer(intra-CRET)initiated by the PO-CL reaction.Consequently,the brightness of the biosensor diminishes proportionally with increasing Cu^(2+)concentrations in human samples.Featuring a low sensing limit of 19.5 nM and an expansive dynamic range spanning from 0.05 to 3.8μM,this biosensor empowers the rapid and precise quantification of trace Cu^(2+)levels with exceptional accuracy and recovery rates.In alignment with copper quantification guidelines set forth by the Environmental Protection Agency(EPA)and the National Institutes of Health(NIH),this selective biosensor stands as a cutting-edge monitoring tool,poised to advance analytical capabilities in various fields.展开更多
20151809 Chen Jun(Institute of Geology and Paleontology,Linyi University,Linyi276000,China);Zhang Haichun A New Genus and Species of Palaeontinidae(Insecta,Hemip-tera)from the Middle Jurassic of Daohugou,Inner Mongoli...20151809 Chen Jun(Institute of Geology and Paleontology,Linyi University,Linyi276000,China);Zhang Haichun A New Genus and Species of Palaeontinidae(Insecta,Hemip-tera)from the Middle Jurassic of Daohugou,Inner Mongolia(Acta Palaeontologica Sinica,展开更多
基金supported by National Natural Science Foundation of China(Nos.22176205,22021003,92043301,21836005)“From 0 to 1”Original Innovation Project,the Basic Frontier Scientific Research Program,CAS(No.ZDBS-LYSLH027)。
文摘We have found recently that two-step intrinsic hydroxyl radical(·OH)-dependent chemiluminescence(CL)could be produced by carcinogenic tetrahaloquinone and H_(2)O_(2).However,the first-step CL was too fast to clearly detect the stepwise generation of·OH and CL,and to distinguish the exact dividing point between the first-step and second-step CL.Here we found that,extremely clear two-step intrinsic CL could be produced by the relative slow reaction of tetrabromohydroquinone(TBHQ)with H_(2)O_(2),which was directly dependent on the two-step·OH generation.Interestingly,the second-step,but not the first-step CL production of TBHQ/H_(2)O_(2)(CRET donor)was markedly enhanced by fluorescein(a typical xanthene dye,CRET acceptor)through a unique chemiluminescence resonance energy transfer(CRET)process.The novel CRET system of TBHQ/H_(2)O_(2)/fluorescein was successfully applied for the sensitive detection of TBHQ with the detection limit as low as 2.5μmol/L.These findings will help to develop more sensitive and highly efficient CL or CRET systems and specific CL sensor to detect the carcinogenic haloquinones,which may have broad environmental applications.
文摘Electrophysical devices based on diathermy are one of the modalities used by many professionals to treat pain. The objective of this study was to identify the effects of Tecartherapy on healthy and unhealthy tissues. A systematic review of Tecartherapy technology was carried out. Articles published up to the year 2023 were investigated. The search argument used was “Capacitive-resistive electrical transfer” OR “Tecar” OR “Therapy Tecar” OR “CRET” in the BVS, Cochrane, PEDro, PubMed, IEEE Explore databases, Scielo and Web of Science. As for the main results of using Tecartherapy, there is an increase in temperature. In healthy tissues there is an increase in local blood flow, a decrease in muscle fatigue and an increase in muscle flexibility. In addition to the effects observed on healthy tissues, pain reduction and improved joint function were also observed. It was concluded that this technology has similar effects to other diathermy, but Tecartherapy proved to be safer and more comfortable. .
基金performed as part of Luminescent MD,LLC’s Research Program(LMD-201)supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2023R1A2C1004109 and 2022R1I1A1A01070007)supported by Korea Energy(No.2024-Research and Development in Field Technology,Yeongheung-01).
文摘Nitrogen-doped carbon quantum dots(N-CQDs),synthesized via the rapid pyrolysis of ammonium citrate dibasic and ethylenediamine dihydrochloride,demonstrate remarkable chemiluminescence capabilities,emitting a vibrant blue-green light in peroxyoxalate chemiluminescence(PO-CL)reactions.Among these,a distinct variant of N-CQDs is an exceptionally sensitive biosensor,facilitating the swift detection of copper ions(Cu^(2+))within human plasma and urine samples.Upon rapid binding of N-CQDs and Cu^(2+),non-emissive complex forms due to intra-chemiluminescence resonance energy transfer(intra-CRET)initiated by the PO-CL reaction.Consequently,the brightness of the biosensor diminishes proportionally with increasing Cu^(2+)concentrations in human samples.Featuring a low sensing limit of 19.5 nM and an expansive dynamic range spanning from 0.05 to 3.8μM,this biosensor empowers the rapid and precise quantification of trace Cu^(2+)levels with exceptional accuracy and recovery rates.In alignment with copper quantification guidelines set forth by the Environmental Protection Agency(EPA)and the National Institutes of Health(NIH),this selective biosensor stands as a cutting-edge monitoring tool,poised to advance analytical capabilities in various fields.
文摘20151809 Chen Jun(Institute of Geology and Paleontology,Linyi University,Linyi276000,China);Zhang Haichun A New Genus and Species of Palaeontinidae(Insecta,Hemip-tera)from the Middle Jurassic of Daohugou,Inner Mongolia(Acta Palaeontologica Sinica,
