Background: Student nurses and other healthcare students are the future mental health professionals and have the potential for changing the future of mental healthcare. Therefore, their negative attitudes and behavior...Background: Student nurses and other healthcare students are the future mental health professionals and have the potential for changing the future of mental healthcare. Therefore, their negative attitudes and behaviors should be screened and corrected by effective anti-stigma interventions. Otherwise, they would likely withhold some health services and practice coercive treatments once planning care to people with mental illness. However, little is known on effective approaches to correct these negative attitudes and behaviors, despite the previous reviews that have shown that contact-based interventions have demonstrated positive attitudinal and behavioral changes for nursing students towards people with mental illness. Aim: The aim of this literature review was to compile the available research evidence on contact-based interventions that have targeted the attitudes and behaviors of nursing students towards people with mental illness. Methods: The relevant literature was extracted by searching electronic databases (MEDLINE, PsycINFO, and CINAHL) and by hand checking reference lists of past similar reviews. Results: Eleven studies were retrieved and included in this review. The included studies in this review either have employed social contact interventions, video-based social contact interventions, or both types for the aim of combining or comparing. Furthermore, the included studies either have targeted the attitudes of nursing students towards people with mental illness (including prejudice), or a combination of attitudinal and behavioral outcomes (including behavioral intentions and social distance). No studies have targeted behavioral outcomes solely. Conclusions: From the available literature, the current authors cannot draw conclusions on the most effective type, form, or ingredients of contact-based interventions among nursing students, as previous literature has large variations. No consistency was found in the previous studies regarding the types or contents of effective contact-based interventions. The compiled evidence in this review, has suggested that contact-based interventions (both social contact and video-based social contact) have been effective in changing the attitudes and behaviors of nursing students favorably, similarly to what previous reviews have found.展开更多
Objective:To analyze the effect of interventional nursing on the therapeutic effect,negative emotion and quality of life of patients undergoing cardiovascular and cerebrovascular interventional therapy.Methods:Eighty-...Objective:To analyze the effect of interventional nursing on the therapeutic effect,negative emotion and quality of life of patients undergoing cardiovascular and cerebrovascular interventional therapy.Methods:Eighty-four patients who received cardio-cerebral vascular interventional therapy in a hospital during January 2024–December 2024 were selected,and were divided into the control group and the observation group by the mean score method,each with 42 cases.The control group was given standardized perioperative care,and the observation group was given interventional nursing intervention on this basis.The two groups were compared in terms of clinical efficacy,negative emotion score,incidence of related complications,quality of life score and nursing satisfaction.Results:The total effective rate of treatment of patients in the observation group(95.24%)was significantly higher than that of the control group(78.57%),and the difference was statistically significant(P<0.05);before nursing care,the difference between SDS and SAS scores of patients in the two groups was insignificant(P>0.05);after nursing care,the scores of various indexes of the two groups were significantly reduced and the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05);the patients in the observation group had more negative moods than those in the control group;the complication rate of patients in the observation group(2.38%)was significantly lower than that of the control group(19.04%),and the difference was statistically significant(P<0.05);the quality of life scores of patients in the observation group were higher than that of the control group,and the difference was statistically significant(P<0.05);the satisfaction rate of patients’nursing care in the observation group was 97.62%,which was higher than that of the control group(78.57%),and the difference was statistically significant(P<0.05).The difference is statistically significant(P<0.05).Conclusion:The implementation of interventional nursing intervention for patients with cardiovascular and cerebrovascular interventional therapy can further enhance the clinical therapeutic effect,improve the negative emotions of patients’anxiety and depression,reduce the risk of related complications,improve the quality of life of patients,and obtain higher satisfaction.展开更多
There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various di...There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various diseases[1−2].While these studies have provided the necessary epidemiological evidence for health authorities in policymaking,it is time to develop and implement tailored health interventions to protect the health and well-being of communities,and particularly that of vulnerable groups.展开更多
Psychological interventions have demonstrated efficacy in improving patients’emotional state,cognition,and thinking abilities,thereby enhancing their quality of life and survival.This review examines literature from ...Psychological interventions have demonstrated efficacy in improving patients’emotional state,cognition,and thinking abilities,thereby enhancing their quality of life and survival.This review examines literature from the China National Knowledge Infrastructure,Wanfang Data,Web of Science,and PubMed databases published over the past decade,focusing on the use of psychotherapy for poststroke anxiety and depression.The prevalence of anxiety and depression is significantly higher among patients who have experienced a stroke than in the general population,possibly due to vestibular dysfunction following brain injury.Current psychological interventions for stroke patients include cognitive behavioral therapy,supportive psychotherapy,music and art therapy,and exercise therapy.These approaches have been shown to promote psychological wellbeing and physical rehabilitation.展开更多
Depression is a common and serious mental disorder,triggered by multiple biological,social and psychological factors.According to the World Health Organization,the incidence of suicide in patients with depression is m...Depression is a common and serious mental disorder,triggered by multiple biological,social and psychological factors.According to the World Health Organization,the incidence of suicide in patients with depression is much higher than in patients with other mental illnesses.Depression has a complex etiology and individual differences,and the effect of single therapy is limited.This review classifies depression into endogenous,exogenous,and secondary categories based on etiology,describes their characteristics,and reviews the research progress of psychological,pharmacological,traditional Chinese medicine,and microbiological interventions.Studies have shown that about 30%-50%of depression has a genetic predisposition;cognitive behavioral therapy is effective for patients with mild-to-moderate depression,and has significant advantages in preventing recurrence,such as networked cognitive behavioral therapy,which is effective in improving mild-to-moderate depressive symptoms,and has a high level of user experience and adherence.Diets rich in dietary fiber,Omega-3 fatty acids,and supplementation with specific probiotics such as Bifidobacterium and Lactobacillus can help alleviate depressive symptoms;preparations of Chinese herbal compounds derived from the Chinese herbal formula,Xiaoyaosan,are effective in alleviating depressive behaviors in mice;and acupuncture is helpful in alleviating primary depression,especially in milder cases.Taken together,gut microbiota influence brain changes through the gut-brain axis.Chinese medicine can realize the combination of Chinese and Western medicine.Both gut microbiota and Chinese medicine show great potential in the treatment of depression.However,the specific therapeutic mechanisms need to be further investigated.展开更多
BACKGROUND Antithrombotic strategies after percutaneous coronary interventions(PCI)in elderly patients on oral anticoagulant therapy(OAT)are debated due to the balance between ischemic and bleeding risks.Recent guidel...BACKGROUND Antithrombotic strategies after percutaneous coronary interventions(PCI)in elderly patients on oral anticoagulant therapy(OAT)are debated due to the balance between ischemic and bleeding risks.Recent guidelines recommend early transitioning from triple antithrombotic therapy to dual antithrombotic therapy,but there are limited data on elderly patients.METHODS We performed a post-hoc age-specific analysis of the PERSEO Registry population aimed to compare clinical features,therapeutic strategies,and outcomes of individuals aged≥80 years and<80 years who were on OAT and underwent PCI with stent.The primary endpoint was net adverse clinical events at 1-year follow-up.Secondary endpoints included major adverse cardiac and cerebral events(MACCE),major bleeding[Bleeding Academic Research Consortium(BARC)type 3–5],and clinically relevant bleeding(BARC type 2-5).RESULTS Among the 1234 patients enrolled,31%of patients were aged≥80 years(84±3 years,76% males).Compared to younger patients,elderly patients had higher rates of comorbidities such as hypertension,anaemia or chronic kidney disease,and atrial fibrillation was the leading indication for OAT.Elderly patients were more often discharged on dual antithrombotic therapy(23%)compared to younger patients(13%)(P<0.0001).They experienced higher net adverse clinical events(38%vs.21%,P<0.001),MACCE(24%vs.12%,P<0.001),as well as higher bleeding rates.Specifically,rates of major bleeding(9%vs.6%,P=0.026),and clinically relevant bleeding(21%vs.12%,P<0.001)were significantly higher in elderly patients.CONCLUSIONS Elderly patients on OAT undergoing PCI are a particular frail population with higher risk of MACCE and bleeding compared to younger patients despite a less aggressive antithrombotic therapy.展开更多
Purpose:This study aimed to provide comparative evidence on the effectiveness of various lifestyle interventions on body composition management for preschool and school-aged children.Methods:PubMed(MEDLINE),Embase,CIN...Purpose:This study aimed to provide comparative evidence on the effectiveness of various lifestyle interventions on body composition management for preschool and school-aged children.Methods:PubMed(MEDLINE),Embase,CINAHL,and Web of Science were systematically searched for this network meta-analysis.Randomized controlled studies(RCTs)that included children aged 4-12 years with no physical or mental conditions;performed at least 1 type of lifestyle intervention;reported change in body mass index(BMI),BMI z-score,or body fat percentage(BFP);and were published between January2010 and August 2023 were included.Results:The final analysis included 91 RCTs with aggregate data for 58,649 children.All interventions were categorized into single-arm approaches(physical activity,diet,and behavioral and informational support)and combined arms approaches(bicomponent and multicomponent treatment).Multicomponent treatment showed significant effectiveness on the reduction of BMI(mean deviation(MD)-0.49,95%confidence interval(95%CI):-0.88 to-0.12),BMI z-score(MD=-0.11,95%CI:-0.18 to-0.04),and BFP(MD=-1.69,95%CI:-2.97 to-0.42)compared to the usual care condition.Bicomponent treatment also significantly reduced BMI(MD=-0.28,95%CI:-0.54 to-0.04)and BMI z-score(MD=-0.07,95%CI:-0.12 to-0.02)compared to usual care.Conclusion:Interventions targeting multiple lifestyle components achieved greater reductions in children's BMI and BFP.Among single-component approaches,physical activity engagement emerged as the most effective.These findings should guide practitioners in recommending comprehensive lifestyle modifications for children.Moreover,children with higher initial BMI and body fat levels tend to exhibit more positive responses to lifestyle interventions aimed at managing obesity.展开更多
Objective:To systematically evaluate the effectiveness of research-oriented integrated nursing interventions on cancer pain management in hospitalized oncology patients in China.Methods:A computerized search of Chines...Objective:To systematically evaluate the effectiveness of research-oriented integrated nursing interventions on cancer pain management in hospitalized oncology patients in China.Methods:A computerized search of Chinese and English databases was conducted to identify relevant studies.Two researchers independently assessed the quality of included literature using the Newcastle-Ottawa Scale(NOS).Data were extracted and analyzed via Stata 14.A random-effects model was applied due to significant heterogeneity(I²>50%).Sensitivity analysis and Egger’s test were performed to assess bias.Results:12 eligible studies(2014-2024)were included.Meta-analysis demonstrated that integrated nursing interventions significantly reduced cancer pain scores compared to routine care(SMD=-1.51,95%CI:-1.90 to-1.12;I²=84.8%),with superior efficacy.Subgroup-analyses revealed enhanced effects for“Nursing modes”(SMD=-2.11)and“cancer pain education”(SMD=-2.30).Conclusion:Research-oriented integrated nursing interventions significantly improve cancer pain management in Chinese hospitalized oncology patients,particularly through synergistic effects of“Nursing modes”and“can-cer pain education.”However,implementation bias from“additive interventions”in teaching hospitals and high heterogeneity warrant attention.Future studies should optimize designs to enhance clinical applicability.展开更多
Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department b...Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department between August 2021 and August 2023 were selected and divided into groups using a random number table. The observation group received preoperative psychological interventions, while the reference group received standard preoperative care. Anxiety and depression scores, fear grading, vital signs, and self-efficacy levels were compared. Results: After the intervention, the anxiety and depression scores in the observation group were lower than those in the reference group, and the proportion of fear graded as Level I was higher. During the waiting period and 15 minutes before entering the operating room, vital sign levels in the observation group were lower than those in the reference group. Additionally, the self-efficacy scores of the observation group were significantly higher than those of the reference group (P < 0.05). Conclusion: Preoperative psychological interventions can alleviate negative emotions, stabilize preoperative vital signs, and significantly improve self-efficacy in patients undergoing elective surgery, demonstrating high feasibility for implementation.展开更多
The initiation and progression of colorectal cancer(CRC)are profoundly influenced by the complex interplay between the gut microbiota and the immune system,underscoring the clinical importance of exploring the bidirec...The initiation and progression of colorectal cancer(CRC)are profoundly influenced by the complex interplay between the gut microbiota and the immune system,underscoring the clinical importance of exploring the bidirectional regulatory mechanisms of the microbiota-immune axis within the CRC immune microenvironment.Emerging evidence indicates that the composition and functional capacity of the gut microbiota play a vital role in modulating the host’s immune responses,while the immune system,in turn,can reciprocally regulate the structure and function of the microbiota.Despite significant insights into the role of the microbiota-immune axis in CRC progression,several critical questions remain unanswered-including how microbial heterogeneity affects therapeutic outcomes and the specific consequences of dysregulated regulatory mechanisms on the immune microenvironment.This review aims to provide a comprehensive analysis of the compositional features of the CRC immune microenvironment,examine the bidirectional molecular mechanisms underpinning the microbiotaimmune axis,and evaluate the potential of targeted therapeutic strategies,thereby offering novel research perspectives and clinical applications for CRC treatment.展开更多
Background Exercise during neoadjuvant chemoradiotherapy(NCRT)has potential to mitigate treatment-related declines in physical fitness,and to improve clinical outcomes,including toxicity and tumor response.However,opt...Background Exercise during neoadjuvant chemoradiotherapy(NCRT)has potential to mitigate treatment-related declines in physical fitness,and to improve clinical outcomes,including toxicity and tumor response.However,optimal frequency and timing of exercise remains to be determined.Therefore,this pilot trial aimed to assess feasibility of 2 different exercise interventions during NCRT in patients with esophageal and rectal cancer and to evaluate potential clinical effects.Methods Patients were randomized into 1 of 3 study arms during NCRT:(a)30-min aerobic exercise in-hospital within 1 h prior to each radiotherapy fraction(ExPR),(b)two 60-min supervised combined aerobic and resistance exercise sessions per week(AE+RE),and(c)usual care(UC).Feasibility was assessed by examining participation rate and exercise adherence.Intervention effects on physical fitness,health-related quality of life,treatment-related toxicity,and tumor response in patients with esophageal cancer were explored using regression analyses and 85%confidence intervals(85%CIs).Results Thirty-seven patients with esophageal cancer(participation rate=45%)and 2 patients with rectal cancer(participation rate=14%)were included.Median session attendance was 98%(interquartile range(IQR):96%–100%)in the ExPR and 78%(IQR:33%–100%)in the AE+RE group.We found clinically relevant benefits of exercise on maximal oxygen uptake(VO2_(max),mL/kg/min)(ExPR:β=9.7,85%CI:6.9–12.6;AE+RE:β=5.6,85%CI:2.6–8.5)and treatment-related toxicity(ExPR:β=–2.8,85%CI:–5.4 to–0.2;AE+RE:β=–2.6,85%CI:–5.3 to 0.0).Additionally,good tumor response was found in 70%in AE+RE and ExPR vs.55%in UC(odds ratio(OR)=1.9,85%CI:0.5–7.7).Conclusion Starting prehabilitation during NCRT is feasible,can increase starting fitness of traditional pre-surgical programs,and has potential to improve clinical outcomes.展开更多
Cancer significantly impacts patients'physical and mental health,leading to a wide range of effects from physical pain to psychological issues such as anxiety and depression,severely diminishing their quality of l...Cancer significantly impacts patients'physical and mental health,leading to a wide range of effects from physical pain to psychological issues such as anxiety and depression,severely diminishing their quality of life.As an emerging psychosomatic intervention,mindfulness interventions have gained increasing attention.This scoping review systematically searches and filters relevant literature,covering databases from their inception to January 2025,aiming to comprehensively outline the application,research characteristics,and main outcomes of mindfulness interventions in cancer recovery.We employed the Arksey and O'Malley framework,utilizing electronic databases and manual searches to rigorously select studies and extract key data.Results indicate that mindfulness interventions show broad potential in improving cancer patients'mental health,physical symptoms,and quality of life,despite the heterogeneity of the evidence.Future research should focus on higher-quality randomized controlled trials to explore different intervention modalities and long-term effects and to analyze their underlying mechanisms.This paper particularly highlights the advancements in Mindfulness-Based Cancer Recovery,providing valuable references for clinical practice.展开更多
Mood disorders include a set of psychiatric manifestations of increasing prevalence in our society,being mainly represented by major depressive disorder(MDD)and bipolar disorder(BD).The etiopathogenesis of mood disord...Mood disorders include a set of psychiatric manifestations of increasing prevalence in our society,being mainly represented by major depressive disorder(MDD)and bipolar disorder(BD).The etiopathogenesis of mood disorders is extremely complex,with a wide spectrum of biological,psychological,and sociocultural factors being responsible for their appearance and development.In this sense,immune system dysfunction represents a key mechanism in the onset and pathophysiology of mood disorders,worsening mainly the central nervous system(neuroinflammation)and the periphery of the body(systemic inflammation).However,these alterations cannot be understood separately,but as part of a complex picture in which different factors and systems interact with each other.Psychoneuroimmunoendocrinology(PNIE)is the area responsible for studying the relationship between these elements and the impact of mind–body integration,placing the immune system as part of a whole.Thus,the dysfunction of the immune system is capable of influencing and activating different mechanisms that promote disruption of the psyche,damage to the nervous system,alterations to the endocrine and metabolic systems,and disruption of the microbiota and intestinal ecosystem,as well as of other organs and,in turn,all these mechanisms are responsible for inducing and enhancing the immune dysfunction.Similarly,the clinical approach to these patients is usually multidisciplinary,and the therapeutic arsenal includes different pharmacological(for example,antidepressants,antipsychotics,and lithium)and non-pharmacological(i.e.,psychotherapy,lifestyle,and electroconvulsive therapy)treatments.These interventions also modulate the immune system and other elements of the PNIE in these patients,which may be interesting to understand the therapeutic success or failure of these approaches.In this sense,this review aims to delve into the relationship between immune dysfunction and mood disorders and their integration in the complex context of PNIE.Likewise,an attempt will be made to explore the effects on the immune system of different strategies available in the clinical approach to these patients,in order to identify the mechanisms described and their possible uses as biomarkers.展开更多
Objective:This scoping review explores digital health interventions used to improve maternal health and the health of children under-5-year-olds in rural areas of low-and middle-income countries(LMICs),identifying cur...Objective:This scoping review explores digital health interventions used to improve maternal health and the health of children under-5-year-olds in rural areas of low-and middle-income countries(LMICs),identifying current practices and research gaps.Methods:Guided by PRISMA Extension for Scoping Reviews,a comprehensive search was conducted across PubMed,Web of Science,and grey literature search with Google Scholar,and the South African National Elec-tronic Theses and Dissertations Portal.MeSH terms and Boolean operators were used.Studies were screened using the Population,Concept,and Context framework,and data were extracted systematically.Results:Of 5,114 records,63 met inclusion criteria.Digital health interventions,particularly mobile health,were found to enhance service delivery,education,and support for maternal and child health in LMICs.However,challenges such as limited access to technology,digital literacy,and cultural barriers persist.Contextual factors,including geography and sociocultural norms,significantly influenced implementation success.Conclusion:Digital health interventions show promise in improving maternal and child health in LMICs.How-ever,regional disparities,technological limitations,and cultural misalignment hinder scalability.Future research should focus on culturally adaptive,community-engaged approaches and long-term impact assessments to sup-port sustainable health promotion in low-resource settings.展开更多
Objective:To assess the method of empathy intervention in nursing students in relation to the three dimensions of empathy:cognitive,affective,and behavioral.Methods:A systematic literature review was conducted followi...Objective:To assess the method of empathy intervention in nursing students in relation to the three dimensions of empathy:cognitive,affective,and behavioral.Methods:A systematic literature review was conducted following the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)2020 guideline.A search for articles in two databases(ScienceDirect and Taylor&Francis)revealed 99 articles.One author independently assessed articles for inclusion,resulting in 10 articles that met the inclusion criteria.Results:Based on a review of ten extracted journal articles,nine interventions showed increases in empathy,while one intervention did not show such outcomes.Four studies(the simulation-based empathic communication training intervention,the situated teaching program,high-fidelity simulation[HFS]training,and the structured empathy educational model[EEM])discussed the impact of interventions on the empathy dimension,while the remaining five only explained the impact of the intervention on empathy in general.Conclusions:The result of this study highlight the need for future research to design empathy interventions for nursing students that effectively target both the affective and behavioral dimensions of empathy.展开更多
Tuberculous meningitis(TBM),which accounts for 1%-5%of global tuberculosis cases,is a severe neurological infection with a mortality rate of 30%-50%.Its high fatality and disability rates disproportionately affect low...Tuberculous meningitis(TBM),which accounts for 1%-5%of global tuberculosis cases,is a severe neurological infection with a mortality rate of 30%-50%.Its high fatality and disability rates disproportionately affect low-and middle-income regions(e.g.,sub-Saharan Africa and Southeast Asia),threatening the lives of patients and imposing significant psychosocial burdens.Recent studies have highlighted the crucial role of psychosocial factors,including socioeconomic status,disease severity,and social support systems in recovery.However,research gaps persist in developing TBM-specific psychosocial interventions.This narrative review summarizes and organizes the key findings of observational studies,cohort studies,and intervention trials published between 2015 and 2024.Databases including PubMed,Scopus,and Web of Science were searched for terms related to TBM,psychosocial risk factors and mental health interventions.Studies were screened for relevance and quality,focusing on those that examined the psychological and social determinants of mental health outcomes in patients with TBM.展开更多
Orthodontic osteodilated arch treatment represents a pivotal approach in dental orthodontics to address dental crowding and misalignment.Integrating cognitive behavioral therapy(CBT)into comprehensive nursing interven...Orthodontic osteodilated arch treatment represents a pivotal approach in dental orthodontics to address dental crowding and misalignment.Integrating cognitive behavioral therapy(CBT)into comprehensive nursing interventions(CNI)aims to address these issues holistically.This editorial explores the effectiveness of CBTbased CNI in improving patient outcomes in orthodontic care.Innovations in remote CBT delivery,such as virtual reality,have also shown potential in reducing pain,anxiety,and depression,emphasizing CBT's adaptability in orthodontic settings.The findings underscore the importance of integrating psychological support into orthodontic care to enhance patient adherence,satisfaction,and overall treatment success.The editorial advocates for a holistic approach that combines psychological and physiological care,highlighting the transformative potential of CBT-based interventions in orthodontic treatment.展开更多
BACKGROUND Implementing nursing interventions in patients undergoing endoscopic treatment for intestinal polyps and early stage cancer can serve as a reference for reducing the incidence of complications,accelerating ...BACKGROUND Implementing nursing interventions in patients undergoing endoscopic treatment for intestinal polyps and early stage cancer can serve as a reference for reducing the incidence of complications,accelerating the recovery process,and improving the quality of life.AIM To impact of systematic nursing intervention on recovery,complications prevention,and quality of life after endoscopic surgery for intestinal polyps.METHODS This retrospective study included 157 patients who underwent endoscopic mucosal resection or endoscopic submucosal dissection at our hospital.The patients were divided into intervention and conventional groups,with no significant differences in age,sex,or surgical methods.The intervention group received multidimensional nursing interventions,including preoperative evaluation,intraoperative cooperation,postoperative rehabilitation,psychological support and nutritional management.The conventional group received standardized care.Clinical efficacy,inflammation and infection indicators,complication rates,rehabilitation indicators,and visual analog scale(VAS)scores were compared.RESULTS On the 7th day after surgery,C-reactive protein(CRP)and white blood cell levels were lower in the intervention group than in the conventional group.Complications occurred in 9.33%of the patients in the intervention group and 23.17%in the conventional group,with significant differences in fever and abdominal distension.The intervention group had shorter first exhaust and hospitalization durations than the control group.By day 3 post-surgery,the intervention group showed lower VAS scores and reduced anxiety and depression.High-risk factors included diabetes[relative risk(RR)=2.43,95%CI:1.21-4.86],laparotomy(RR=2.86,95%CI:1.22-6.71),CRP>15 mg/L(RR=3.12,95%CI:1.54-6.33),and procalcitonin>0.5 ng/mL 1 day after surgery(RR=2.91.95%CI:1.31-6.44),while systematic nursing interventions(OR=0.40,95%CI:0.18-0.89)reduced the complication risk by 60%.CONCLUSION Multidimensional nursing interventions have clinical value in endoscopic treatment of intestinal polyps and early stage cancer,reducing complications and hospital stay.This study provides a basis for establishing patientcentered guidelines.展开更多
Psychiatric disorders significantly impact surgical outcomes,presenting unique challenges in perioperative care.The intricate relationship between preoperative psychiatric conditions and surgical complications involve...Psychiatric disorders significantly impact surgical outcomes,presenting unique challenges in perioperative care.The intricate relationship between preoperative psychiatric conditions and surgical complications involves complex mechanisms,including altered coagulation,cardiovascular function,and pain perception.Common psychiatric disorders in surgical patients,such as anxiety,depression,and substance use disorders,vary in prevalence and manifestation.Demographic factors,comorbidities,and psychotropic medications further modulate these effects on surgical outcomes.Effective screening and assessment strategies are crucial,yet they present both opportunities and limitations in the preoperative setting.Preoperative psychological interventions,including cognitive-behavioral therapy,supportive care,and mind-body techniques,show promise in mitigating psychological distress and improving surgical outcomes.Multidisciplinary approaches,involving collaborative efforts between psychiatric and surgical teams,are essential to provide comprehensive patient care.Emerging inter-ventions,technological innovations,and personalized medicine approaches offer exciting possibilities to advance preoperative psychiatric care.By understanding the complex interplay between psychiatric disorders and surgical outcomes,healthcare professionals can implement integrated,patient-centered approaches to optimize perioperative care and improve overall patient outcomes.展开更多
BACKGROUND Internet gaming disorder(IGD)is a growing concern among adolescents and adults,necessitating effective treatment strategies beyond pharmacological interventions.AIM To evaluated the effectiveness of non-inv...BACKGROUND Internet gaming disorder(IGD)is a growing concern among adolescents and adults,necessitating effective treatment strategies beyond pharmacological interventions.AIM To evaluated the effectiveness of non-invasive interventions for treating IGD among adolescents and adults.METHODS A total of 11 randomized controlled trials published between 2020 and 2025 were included in this meta-analysis,encompassing 1208 participants from diverse geographic and cultural contexts.The interventions examined included cognitive behavioral therapy(CBT),internet-based CBT,neurofeedback,virtual reality therapy,abstinence-based programs,and school-based prevention.The primary outcomes assessed were reductions in gaming time and IGD severity.Secondary outcomes included improvements in mood,anxiety,and psychosocial functioning(e.g.,stronger peer relationships,better academic or work performance,and healthier daily-life role fulfillment).RESULTS The pooled standardized mean difference for IGD symptom reduction significantly favored non-invasive interventions(Hedges’g=0.56,95%CI:0.38-0.74,P<0.001),with moderate heterogeneity observed(I2=47%).Subgroup analyses indicated that CBT-based programs,both in-person and online,yielded the strongest effects,particularly when caregiver involvement or self-monitoring was incorporated.Funnel plot asymmetry was minimal,suggesting a low risk of publication bias.CONCLUSION These findings support the efficacy of scalable,low-risk non-invasive interventions as first-line treatment options for IGD,particularly in youth populations.Future studies should prioritize investigating long-term outcomes,comparing the effectiveness of different non-invasive modalities,and developing culturally adaptive delivery methods.展开更多
文摘Background: Student nurses and other healthcare students are the future mental health professionals and have the potential for changing the future of mental healthcare. Therefore, their negative attitudes and behaviors should be screened and corrected by effective anti-stigma interventions. Otherwise, they would likely withhold some health services and practice coercive treatments once planning care to people with mental illness. However, little is known on effective approaches to correct these negative attitudes and behaviors, despite the previous reviews that have shown that contact-based interventions have demonstrated positive attitudinal and behavioral changes for nursing students towards people with mental illness. Aim: The aim of this literature review was to compile the available research evidence on contact-based interventions that have targeted the attitudes and behaviors of nursing students towards people with mental illness. Methods: The relevant literature was extracted by searching electronic databases (MEDLINE, PsycINFO, and CINAHL) and by hand checking reference lists of past similar reviews. Results: Eleven studies were retrieved and included in this review. The included studies in this review either have employed social contact interventions, video-based social contact interventions, or both types for the aim of combining or comparing. Furthermore, the included studies either have targeted the attitudes of nursing students towards people with mental illness (including prejudice), or a combination of attitudinal and behavioral outcomes (including behavioral intentions and social distance). No studies have targeted behavioral outcomes solely. Conclusions: From the available literature, the current authors cannot draw conclusions on the most effective type, form, or ingredients of contact-based interventions among nursing students, as previous literature has large variations. No consistency was found in the previous studies regarding the types or contents of effective contact-based interventions. The compiled evidence in this review, has suggested that contact-based interventions (both social contact and video-based social contact) have been effective in changing the attitudes and behaviors of nursing students favorably, similarly to what previous reviews have found.
文摘Objective:To analyze the effect of interventional nursing on the therapeutic effect,negative emotion and quality of life of patients undergoing cardiovascular and cerebrovascular interventional therapy.Methods:Eighty-four patients who received cardio-cerebral vascular interventional therapy in a hospital during January 2024–December 2024 were selected,and were divided into the control group and the observation group by the mean score method,each with 42 cases.The control group was given standardized perioperative care,and the observation group was given interventional nursing intervention on this basis.The two groups were compared in terms of clinical efficacy,negative emotion score,incidence of related complications,quality of life score and nursing satisfaction.Results:The total effective rate of treatment of patients in the observation group(95.24%)was significantly higher than that of the control group(78.57%),and the difference was statistically significant(P<0.05);before nursing care,the difference between SDS and SAS scores of patients in the two groups was insignificant(P>0.05);after nursing care,the scores of various indexes of the two groups were significantly reduced and the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05);the patients in the observation group had more negative moods than those in the control group;the complication rate of patients in the observation group(2.38%)was significantly lower than that of the control group(19.04%),and the difference was statistically significant(P<0.05);the quality of life scores of patients in the observation group were higher than that of the control group,and the difference was statistically significant(P<0.05);the satisfaction rate of patients’nursing care in the observation group was 97.62%,which was higher than that of the control group(78.57%),and the difference was statistically significant(P<0.05).The difference is statistically significant(P<0.05).Conclusion:The implementation of interventional nursing intervention for patients with cardiovascular and cerebrovascular interventional therapy can further enhance the clinical therapeutic effect,improve the negative emotions of patients’anxiety and depression,reduce the risk of related complications,improve the quality of life of patients,and obtain higher satisfaction.
文摘There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various diseases[1−2].While these studies have provided the necessary epidemiological evidence for health authorities in policymaking,it is time to develop and implement tailored health interventions to protect the health and well-being of communities,and particularly that of vulnerable groups.
文摘Psychological interventions have demonstrated efficacy in improving patients’emotional state,cognition,and thinking abilities,thereby enhancing their quality of life and survival.This review examines literature from the China National Knowledge Infrastructure,Wanfang Data,Web of Science,and PubMed databases published over the past decade,focusing on the use of psychotherapy for poststroke anxiety and depression.The prevalence of anxiety and depression is significantly higher among patients who have experienced a stroke than in the general population,possibly due to vestibular dysfunction following brain injury.Current psychological interventions for stroke patients include cognitive behavioral therapy,supportive psychotherapy,music and art therapy,and exercise therapy.These approaches have been shown to promote psychological wellbeing and physical rehabilitation.
基金Yan’an University Students Innovation and Entrepreneurship project funding(202310719006)the National Nature Science Foundation of Chinasupported by the National Nature Science Foundation of China(31160004).
文摘Depression is a common and serious mental disorder,triggered by multiple biological,social and psychological factors.According to the World Health Organization,the incidence of suicide in patients with depression is much higher than in patients with other mental illnesses.Depression has a complex etiology and individual differences,and the effect of single therapy is limited.This review classifies depression into endogenous,exogenous,and secondary categories based on etiology,describes their characteristics,and reviews the research progress of psychological,pharmacological,traditional Chinese medicine,and microbiological interventions.Studies have shown that about 30%-50%of depression has a genetic predisposition;cognitive behavioral therapy is effective for patients with mild-to-moderate depression,and has significant advantages in preventing recurrence,such as networked cognitive behavioral therapy,which is effective in improving mild-to-moderate depressive symptoms,and has a high level of user experience and adherence.Diets rich in dietary fiber,Omega-3 fatty acids,and supplementation with specific probiotics such as Bifidobacterium and Lactobacillus can help alleviate depressive symptoms;preparations of Chinese herbal compounds derived from the Chinese herbal formula,Xiaoyaosan,are effective in alleviating depressive behaviors in mice;and acupuncture is helpful in alleviating primary depression,especially in milder cases.Taken together,gut microbiota influence brain changes through the gut-brain axis.Chinese medicine can realize the combination of Chinese and Western medicine.Both gut microbiota and Chinese medicine show great potential in the treatment of depression.However,the specific therapeutic mechanisms need to be further investigated.
基金was given by a 2017 Research Grant of the Italian Society of Interventional Cardiology (SICI-GISE)
文摘BACKGROUND Antithrombotic strategies after percutaneous coronary interventions(PCI)in elderly patients on oral anticoagulant therapy(OAT)are debated due to the balance between ischemic and bleeding risks.Recent guidelines recommend early transitioning from triple antithrombotic therapy to dual antithrombotic therapy,but there are limited data on elderly patients.METHODS We performed a post-hoc age-specific analysis of the PERSEO Registry population aimed to compare clinical features,therapeutic strategies,and outcomes of individuals aged≥80 years and<80 years who were on OAT and underwent PCI with stent.The primary endpoint was net adverse clinical events at 1-year follow-up.Secondary endpoints included major adverse cardiac and cerebral events(MACCE),major bleeding[Bleeding Academic Research Consortium(BARC)type 3–5],and clinically relevant bleeding(BARC type 2-5).RESULTS Among the 1234 patients enrolled,31%of patients were aged≥80 years(84±3 years,76% males).Compared to younger patients,elderly patients had higher rates of comorbidities such as hypertension,anaemia or chronic kidney disease,and atrial fibrillation was the leading indication for OAT.Elderly patients were more often discharged on dual antithrombotic therapy(23%)compared to younger patients(13%)(P<0.0001).They experienced higher net adverse clinical events(38%vs.21%,P<0.001),MACCE(24%vs.12%,P<0.001),as well as higher bleeding rates.Specifically,rates of major bleeding(9%vs.6%,P=0.026),and clinically relevant bleeding(21%vs.12%,P<0.001)were significantly higher in elderly patients.CONCLUSIONS Elderly patients on OAT undergoing PCI are a particular frail population with higher risk of MACCE and bleeding compared to younger patients despite a less aggressive antithrombotic therapy.
文摘Purpose:This study aimed to provide comparative evidence on the effectiveness of various lifestyle interventions on body composition management for preschool and school-aged children.Methods:PubMed(MEDLINE),Embase,CINAHL,and Web of Science were systematically searched for this network meta-analysis.Randomized controlled studies(RCTs)that included children aged 4-12 years with no physical or mental conditions;performed at least 1 type of lifestyle intervention;reported change in body mass index(BMI),BMI z-score,or body fat percentage(BFP);and were published between January2010 and August 2023 were included.Results:The final analysis included 91 RCTs with aggregate data for 58,649 children.All interventions were categorized into single-arm approaches(physical activity,diet,and behavioral and informational support)and combined arms approaches(bicomponent and multicomponent treatment).Multicomponent treatment showed significant effectiveness on the reduction of BMI(mean deviation(MD)-0.49,95%confidence interval(95%CI):-0.88 to-0.12),BMI z-score(MD=-0.11,95%CI:-0.18 to-0.04),and BFP(MD=-1.69,95%CI:-2.97 to-0.42)compared to the usual care condition.Bicomponent treatment also significantly reduced BMI(MD=-0.28,95%CI:-0.54 to-0.04)and BMI z-score(MD=-0.07,95%CI:-0.12 to-0.02)compared to usual care.Conclusion:Interventions targeting multiple lifestyle components achieved greater reductions in children's BMI and BFP.Among single-component approaches,physical activity engagement emerged as the most effective.These findings should guide practitioners in recommending comprehensive lifestyle modifications for children.Moreover,children with higher initial BMI and body fat levels tend to exhibit more positive responses to lifestyle interventions aimed at managing obesity.
文摘Objective:To systematically evaluate the effectiveness of research-oriented integrated nursing interventions on cancer pain management in hospitalized oncology patients in China.Methods:A computerized search of Chinese and English databases was conducted to identify relevant studies.Two researchers independently assessed the quality of included literature using the Newcastle-Ottawa Scale(NOS).Data were extracted and analyzed via Stata 14.A random-effects model was applied due to significant heterogeneity(I²>50%).Sensitivity analysis and Egger’s test were performed to assess bias.Results:12 eligible studies(2014-2024)were included.Meta-analysis demonstrated that integrated nursing interventions significantly reduced cancer pain scores compared to routine care(SMD=-1.51,95%CI:-1.90 to-1.12;I²=84.8%),with superior efficacy.Subgroup-analyses revealed enhanced effects for“Nursing modes”(SMD=-2.11)and“cancer pain education”(SMD=-2.30).Conclusion:Research-oriented integrated nursing interventions significantly improve cancer pain management in Chinese hospitalized oncology patients,particularly through synergistic effects of“Nursing modes”and“can-cer pain education.”However,implementation bias from“additive interventions”in teaching hospitals and high heterogeneity warrant attention.Future studies should optimize designs to enhance clinical applicability.
文摘Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department between August 2021 and August 2023 were selected and divided into groups using a random number table. The observation group received preoperative psychological interventions, while the reference group received standard preoperative care. Anxiety and depression scores, fear grading, vital signs, and self-efficacy levels were compared. Results: After the intervention, the anxiety and depression scores in the observation group were lower than those in the reference group, and the proportion of fear graded as Level I was higher. During the waiting period and 15 minutes before entering the operating room, vital sign levels in the observation group were lower than those in the reference group. Additionally, the self-efficacy scores of the observation group were significantly higher than those of the reference group (P < 0.05). Conclusion: Preoperative psychological interventions can alleviate negative emotions, stabilize preoperative vital signs, and significantly improve self-efficacy in patients undergoing elective surgery, demonstrating high feasibility for implementation.
文摘The initiation and progression of colorectal cancer(CRC)are profoundly influenced by the complex interplay between the gut microbiota and the immune system,underscoring the clinical importance of exploring the bidirectional regulatory mechanisms of the microbiota-immune axis within the CRC immune microenvironment.Emerging evidence indicates that the composition and functional capacity of the gut microbiota play a vital role in modulating the host’s immune responses,while the immune system,in turn,can reciprocally regulate the structure and function of the microbiota.Despite significant insights into the role of the microbiota-immune axis in CRC progression,several critical questions remain unanswered-including how microbial heterogeneity affects therapeutic outcomes and the specific consequences of dysregulated regulatory mechanisms on the immune microenvironment.This review aims to provide a comprehensive analysis of the compositional features of the CRC immune microenvironment,examine the bidirectional molecular mechanisms underpinning the microbiotaimmune axis,and evaluate the potential of targeted therapeutic strategies,thereby offering novel research perspectives and clinical applications for CRC treatment.
基金supported by the Hypatia Fellowship grant from Radboudumc awarded to LB.
文摘Background Exercise during neoadjuvant chemoradiotherapy(NCRT)has potential to mitigate treatment-related declines in physical fitness,and to improve clinical outcomes,including toxicity and tumor response.However,optimal frequency and timing of exercise remains to be determined.Therefore,this pilot trial aimed to assess feasibility of 2 different exercise interventions during NCRT in patients with esophageal and rectal cancer and to evaluate potential clinical effects.Methods Patients were randomized into 1 of 3 study arms during NCRT:(a)30-min aerobic exercise in-hospital within 1 h prior to each radiotherapy fraction(ExPR),(b)two 60-min supervised combined aerobic and resistance exercise sessions per week(AE+RE),and(c)usual care(UC).Feasibility was assessed by examining participation rate and exercise adherence.Intervention effects on physical fitness,health-related quality of life,treatment-related toxicity,and tumor response in patients with esophageal cancer were explored using regression analyses and 85%confidence intervals(85%CIs).Results Thirty-seven patients with esophageal cancer(participation rate=45%)and 2 patients with rectal cancer(participation rate=14%)were included.Median session attendance was 98%(interquartile range(IQR):96%–100%)in the ExPR and 78%(IQR:33%–100%)in the AE+RE group.We found clinically relevant benefits of exercise on maximal oxygen uptake(VO2_(max),mL/kg/min)(ExPR:β=9.7,85%CI:6.9–12.6;AE+RE:β=5.6,85%CI:2.6–8.5)and treatment-related toxicity(ExPR:β=–2.8,85%CI:–5.4 to–0.2;AE+RE:β=–2.6,85%CI:–5.3 to 0.0).Additionally,good tumor response was found in 70%in AE+RE and ExPR vs.55%in UC(odds ratio(OR)=1.9,85%CI:0.5–7.7).Conclusion Starting prehabilitation during NCRT is feasible,can increase starting fitness of traditional pre-surgical programs,and has potential to improve clinical outcomes.
基金Supported by the Teacher Education Research Project of Meizhouwan Vocational and Technical College,No.MZY2407Fujian Province Lifelong Education Quality Enhancement and Excellence Training Project,No.ZS24037.
文摘Cancer significantly impacts patients'physical and mental health,leading to a wide range of effects from physical pain to psychological issues such as anxiety and depression,severely diminishing their quality of life.As an emerging psychosomatic intervention,mindfulness interventions have gained increasing attention.This scoping review systematically searches and filters relevant literature,covering databases from their inception to January 2025,aiming to comprehensively outline the application,research characteristics,and main outcomes of mindfulness interventions in cancer recovery.We employed the Arksey and O'Malley framework,utilizing electronic databases and manual searches to rigorously select studies and extract key data.Results indicate that mindfulness interventions show broad potential in improving cancer patients'mental health,physical symptoms,and quality of life,despite the heterogeneity of the evidence.Future research should focus on higher-quality randomized controlled trials to explore different intervention modalities and long-term effects and to analyze their underlying mechanisms.This paper particularly highlights the advancements in Mindfulness-Based Cancer Recovery,providing valuable references for clinical practice.
基金supported by the Instituto de Salud Carlos III(EstataldeI+D+I2020-2027)co-financed by the European Development Regional Fund“A way to achieve Europe”P2022/BMD-7321(Comunidad de Madrid)and ProACapital,Halekulani S.L.and MJR.
文摘Mood disorders include a set of psychiatric manifestations of increasing prevalence in our society,being mainly represented by major depressive disorder(MDD)and bipolar disorder(BD).The etiopathogenesis of mood disorders is extremely complex,with a wide spectrum of biological,psychological,and sociocultural factors being responsible for their appearance and development.In this sense,immune system dysfunction represents a key mechanism in the onset and pathophysiology of mood disorders,worsening mainly the central nervous system(neuroinflammation)and the periphery of the body(systemic inflammation).However,these alterations cannot be understood separately,but as part of a complex picture in which different factors and systems interact with each other.Psychoneuroimmunoendocrinology(PNIE)is the area responsible for studying the relationship between these elements and the impact of mind–body integration,placing the immune system as part of a whole.Thus,the dysfunction of the immune system is capable of influencing and activating different mechanisms that promote disruption of the psyche,damage to the nervous system,alterations to the endocrine and metabolic systems,and disruption of the microbiota and intestinal ecosystem,as well as of other organs and,in turn,all these mechanisms are responsible for inducing and enhancing the immune dysfunction.Similarly,the clinical approach to these patients is usually multidisciplinary,and the therapeutic arsenal includes different pharmacological(for example,antidepressants,antipsychotics,and lithium)and non-pharmacological(i.e.,psychotherapy,lifestyle,and electroconvulsive therapy)treatments.These interventions also modulate the immune system and other elements of the PNIE in these patients,which may be interesting to understand the therapeutic success or failure of these approaches.In this sense,this review aims to delve into the relationship between immune dysfunction and mood disorders and their integration in the complex context of PNIE.Likewise,an attempt will be made to explore the effects on the immune system of different strategies available in the clinical approach to these patients,in order to identify the mechanisms described and their possible uses as biomarkers.
文摘Objective:This scoping review explores digital health interventions used to improve maternal health and the health of children under-5-year-olds in rural areas of low-and middle-income countries(LMICs),identifying current practices and research gaps.Methods:Guided by PRISMA Extension for Scoping Reviews,a comprehensive search was conducted across PubMed,Web of Science,and grey literature search with Google Scholar,and the South African National Elec-tronic Theses and Dissertations Portal.MeSH terms and Boolean operators were used.Studies were screened using the Population,Concept,and Context framework,and data were extracted systematically.Results:Of 5,114 records,63 met inclusion criteria.Digital health interventions,particularly mobile health,were found to enhance service delivery,education,and support for maternal and child health in LMICs.However,challenges such as limited access to technology,digital literacy,and cultural barriers persist.Contextual factors,including geography and sociocultural norms,significantly influenced implementation success.Conclusion:Digital health interventions show promise in improving maternal and child health in LMICs.How-ever,regional disparities,technological limitations,and cultural misalignment hinder scalability.Future research should focus on culturally adaptive,community-engaged approaches and long-term impact assessments to sup-port sustainable health promotion in low-resource settings.
文摘Objective:To assess the method of empathy intervention in nursing students in relation to the three dimensions of empathy:cognitive,affective,and behavioral.Methods:A systematic literature review was conducted following the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)2020 guideline.A search for articles in two databases(ScienceDirect and Taylor&Francis)revealed 99 articles.One author independently assessed articles for inclusion,resulting in 10 articles that met the inclusion criteria.Results:Based on a review of ten extracted journal articles,nine interventions showed increases in empathy,while one intervention did not show such outcomes.Four studies(the simulation-based empathic communication training intervention,the situated teaching program,high-fidelity simulation[HFS]training,and the structured empathy educational model[EEM])discussed the impact of interventions on the empathy dimension,while the remaining five only explained the impact of the intervention on empathy in general.Conclusions:The result of this study highlight the need for future research to design empathy interventions for nursing students that effectively target both the affective and behavioral dimensions of empathy.
文摘Tuberculous meningitis(TBM),which accounts for 1%-5%of global tuberculosis cases,is a severe neurological infection with a mortality rate of 30%-50%.Its high fatality and disability rates disproportionately affect low-and middle-income regions(e.g.,sub-Saharan Africa and Southeast Asia),threatening the lives of patients and imposing significant psychosocial burdens.Recent studies have highlighted the crucial role of psychosocial factors,including socioeconomic status,disease severity,and social support systems in recovery.However,research gaps persist in developing TBM-specific psychosocial interventions.This narrative review summarizes and organizes the key findings of observational studies,cohort studies,and intervention trials published between 2015 and 2024.Databases including PubMed,Scopus,and Web of Science were searched for terms related to TBM,psychosocial risk factors and mental health interventions.Studies were screened for relevance and quality,focusing on those that examined the psychological and social determinants of mental health outcomes in patients with TBM.
基金Basic Science Research Program Through the National Research Foundation of Korea Funded by the Ministry of Education,No.NRF-RS-2023-00237287 and No.NRF-2021S1A5A8062526Local Government-University Cooperation-Based Regional Innovation Projects,No.2021RIS-003.
文摘Orthodontic osteodilated arch treatment represents a pivotal approach in dental orthodontics to address dental crowding and misalignment.Integrating cognitive behavioral therapy(CBT)into comprehensive nursing interventions(CNI)aims to address these issues holistically.This editorial explores the effectiveness of CBTbased CNI in improving patient outcomes in orthodontic care.Innovations in remote CBT delivery,such as virtual reality,have also shown potential in reducing pain,anxiety,and depression,emphasizing CBT's adaptability in orthodontic settings.The findings underscore the importance of integrating psychological support into orthodontic care to enhance patient adherence,satisfaction,and overall treatment success.The editorial advocates for a holistic approach that combines psychological and physiological care,highlighting the transformative potential of CBT-based interventions in orthodontic treatment.
文摘BACKGROUND Implementing nursing interventions in patients undergoing endoscopic treatment for intestinal polyps and early stage cancer can serve as a reference for reducing the incidence of complications,accelerating the recovery process,and improving the quality of life.AIM To impact of systematic nursing intervention on recovery,complications prevention,and quality of life after endoscopic surgery for intestinal polyps.METHODS This retrospective study included 157 patients who underwent endoscopic mucosal resection or endoscopic submucosal dissection at our hospital.The patients were divided into intervention and conventional groups,with no significant differences in age,sex,or surgical methods.The intervention group received multidimensional nursing interventions,including preoperative evaluation,intraoperative cooperation,postoperative rehabilitation,psychological support and nutritional management.The conventional group received standardized care.Clinical efficacy,inflammation and infection indicators,complication rates,rehabilitation indicators,and visual analog scale(VAS)scores were compared.RESULTS On the 7th day after surgery,C-reactive protein(CRP)and white blood cell levels were lower in the intervention group than in the conventional group.Complications occurred in 9.33%of the patients in the intervention group and 23.17%in the conventional group,with significant differences in fever and abdominal distension.The intervention group had shorter first exhaust and hospitalization durations than the control group.By day 3 post-surgery,the intervention group showed lower VAS scores and reduced anxiety and depression.High-risk factors included diabetes[relative risk(RR)=2.43,95%CI:1.21-4.86],laparotomy(RR=2.86,95%CI:1.22-6.71),CRP>15 mg/L(RR=3.12,95%CI:1.54-6.33),and procalcitonin>0.5 ng/mL 1 day after surgery(RR=2.91.95%CI:1.31-6.44),while systematic nursing interventions(OR=0.40,95%CI:0.18-0.89)reduced the complication risk by 60%.CONCLUSION Multidimensional nursing interventions have clinical value in endoscopic treatment of intestinal polyps and early stage cancer,reducing complications and hospital stay.This study provides a basis for establishing patientcentered guidelines.
文摘Psychiatric disorders significantly impact surgical outcomes,presenting unique challenges in perioperative care.The intricate relationship between preoperative psychiatric conditions and surgical complications involves complex mechanisms,including altered coagulation,cardiovascular function,and pain perception.Common psychiatric disorders in surgical patients,such as anxiety,depression,and substance use disorders,vary in prevalence and manifestation.Demographic factors,comorbidities,and psychotropic medications further modulate these effects on surgical outcomes.Effective screening and assessment strategies are crucial,yet they present both opportunities and limitations in the preoperative setting.Preoperative psychological interventions,including cognitive-behavioral therapy,supportive care,and mind-body techniques,show promise in mitigating psychological distress and improving surgical outcomes.Multidisciplinary approaches,involving collaborative efforts between psychiatric and surgical teams,are essential to provide comprehensive patient care.Emerging inter-ventions,technological innovations,and personalized medicine approaches offer exciting possibilities to advance preoperative psychiatric care.By understanding the complex interplay between psychiatric disorders and surgical outcomes,healthcare professionals can implement integrated,patient-centered approaches to optimize perioperative care and improve overall patient outcomes.
基金Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)Funded by the Ministry of Education,No.NRF-RS-2023-00237287.
文摘BACKGROUND Internet gaming disorder(IGD)is a growing concern among adolescents and adults,necessitating effective treatment strategies beyond pharmacological interventions.AIM To evaluated the effectiveness of non-invasive interventions for treating IGD among adolescents and adults.METHODS A total of 11 randomized controlled trials published between 2020 and 2025 were included in this meta-analysis,encompassing 1208 participants from diverse geographic and cultural contexts.The interventions examined included cognitive behavioral therapy(CBT),internet-based CBT,neurofeedback,virtual reality therapy,abstinence-based programs,and school-based prevention.The primary outcomes assessed were reductions in gaming time and IGD severity.Secondary outcomes included improvements in mood,anxiety,and psychosocial functioning(e.g.,stronger peer relationships,better academic or work performance,and healthier daily-life role fulfillment).RESULTS The pooled standardized mean difference for IGD symptom reduction significantly favored non-invasive interventions(Hedges’g=0.56,95%CI:0.38-0.74,P<0.001),with moderate heterogeneity observed(I2=47%).Subgroup analyses indicated that CBT-based programs,both in-person and online,yielded the strongest effects,particularly when caregiver involvement or self-monitoring was incorporated.Funnel plot asymmetry was minimal,suggesting a low risk of publication bias.CONCLUSION These findings support the efficacy of scalable,low-risk non-invasive interventions as first-line treatment options for IGD,particularly in youth populations.Future studies should prioritize investigating long-term outcomes,comparing the effectiveness of different non-invasive modalities,and developing culturally adaptive delivery methods.
