The assessment of translation quality in political texts is primarily based on achieving effective communication.Throughout the translation process,it is essential to not only accurately convey the original content bu...The assessment of translation quality in political texts is primarily based on achieving effective communication.Throughout the translation process,it is essential to not only accurately convey the original content but also effectively transform the structural mechanisms of the source language.In the translation reconstruction of political texts,various textual cohesion methods are often employed,with conjunctions serving as a primary means for semantic coherence within text units.展开更多
From the study of polysemy of coordinate conjunctions, it can be found that there are grammaticalization processes from coordination to transition and from coordination to succession. It is a general evolutionary proc...From the study of polysemy of coordinate conjunctions, it can be found that there are grammaticalization processes from coordination to transition and from coordination to succession. It is a general evolutionary process in connective structures to go from non-specific semantic relationship to specific semantic relationship. This was caused by the cognitive tendency of approximately substituting typical functions for atypical functions.展开更多
Corpus is a kind of database that may contain texts in a single language(monolingual corpus)or text data in multiple languages(multilingual corpus).Most of the words can be involved in such a database,so it is provide...Corpus is a kind of database that may contain texts in a single language(monolingual corpus)or text data in multiple languages(multilingual corpus).Most of the words can be involved in such a database,so it is provided with significant realistic meaning for language learners.Also,the use of causality conjunction in Korean plays a more important guiding role in listening,speaking,reading and writing of Korean.However,the status with regard to the application of causality conjunction in Korean is not optimistic and the problems such as the improper use of language,lack of knowledge about conjunction by learners,short of professional Korean teaching consciousness by teachers and others are being,thereby seriously hindering the learning interests of Korean learners and educational progress.Thus,in accordance with research status at home and abroad,this paper carries out indepth analysis on the basic theory of corpus and Korean conjunction as well as the application of causality conjunction in Korean based on the corpus.And it can be found that the research on the application of causality conjunction in Korean based on corpus is with important value for both the flexible use of language and the improvement of comprehensive application ability of language.展开更多
The paper explored the development of successive conjunctions from Archaic Chinese to Contemporary Chinese from a macroscopic perspective.Data statistics and diachronic study method were adopted in this paper,and the ...The paper explored the development of successive conjunctions from Archaic Chinese to Contemporary Chinese from a macroscopic perspective.Data statistics and diachronic study method were adopted in this paper,and the results indicated that a quantity of new successive conjunctions have been produced both in Archaic Chinese and Mid-ancient Chinese,and at the same time a very large proportion of the old successive conjunctions were superseded by the new.Those which appeared in very few types of corpus and have low frequency of use are more likely to be eliminated.In Contemporary Chinese,the successive conjunction system tends to be stable and concise.展开更多
The present study is a contrastive study of inter-sentence conjunctions in Chinese/English legal parallel texts. Conjunction is one of the five cohesive devices put forward by Halliday and Hasan (1976). Many scholars ...The present study is a contrastive study of inter-sentence conjunctions in Chinese/English legal parallel texts. Conjunction is one of the five cohesive devices put forward by Halliday and Hasan (1976). Many scholars have applied their model of cohesion to the study of English and Chinese languages. As for the use of conjunction in Chinese and English, most scholars believe that there are more cases of conjunction in the English legal texts than in the Chinese ones because it is generally considered that Chinese is predominantly paratactic and English mainly hypotactic. Besides, up to now little detailed contrastive study has been done on conjunctions in Chinese/English non-literary texts.展开更多
Language transfer is one of the most significant aspects of cross-linguistic influ-ence.It can be divided into two types:positive and negative,the beneficial and det-rimental use of one language's acquired charact...Language transfer is one of the most significant aspects of cross-linguistic influ-ence.It can be divided into two types:positive and negative,the beneficial and det-rimental use of one language's acquired characteristics in another.This study aims to investigate the L1(Chinese)influence on Hong Kong ESL learners'acquisition of conjunctions and whether the use of L1 has an impact on this influence.An online questionnaire combining questions about students'English learning experience and a grammatical judgement task was sent to a government-funded secondary school in Hong Kong and completed by 79 students.Evidence of both positive and negative transfer from Chinese to English was found by testing six conjunctions or conjunc-tion pairs:although...but,because...so,not only...but also,either...or,neither...nor,.and despite.The results suggest that Chinese is likely to have an impact on students'acquisition of conjunctions,and the use of Chinese in English classes can worsen negative transfer and boost positive transfer.The degree of transfer might increase when more Chinese is used in class.To alleviate the impact of Chinese transfer and to provide more effective L2 teaching,monitoring the use of L1 and regular evalua-tion might be useful.Teachers can also adjust the amount of Chinese used according to the students'English proficiency level.展开更多
Linking words,also called transition words,are quite useful in English expressions.Linking words are not the same as conjunctions,although some conjunctions can function as linking words.Here's a clear explanation...Linking words,also called transition words,are quite useful in English expressions.Linking words are not the same as conjunctions,although some conjunctions can function as linking words.Here's a clear explanation for English learners,followed by a wellorganized passage on the functions of linking words in writing and communication.展开更多
Allergic conjunctivitis is a common ocular surface condition.Although corticosteroids are potent antiinflammatory agents for its management,their use is often restricted by potential side effects.Conventional eye drop...Allergic conjunctivitis is a common ocular surface condition.Although corticosteroids are potent antiinflammatory agents for its management,their use is often restricted by potential side effects.Conventional eye drops face challenges such as short retention time and poor corneal permeability,resulting in low drug bioavailability.To overcome these limitations,we developed a preservative-free synthetic high-density lipoprotein(sHDL)nanodisc eye drop containing dexamethasone palmitate.This novel formulation enhances drug stability and extends retention time on the ocular surface.In a mouse model of ovalbumin(OVA)-induced allergic conjunctivitis,the nanodisc eye drop significantly alleviated symptoms while reducing corticosteroid concentration,demonstrating excellent safety and biocompatibility.This innovative approach shows great promise for the treatment of allergic conjunctivitis and may lay the groundwork for new therapeutic strategies in anterior ocular disease management.展开更多
Red eye affects patients of all ages and is one of the most common ocular complaints seen in primary care and emergency rooms.Some conditions,like scleritis,keratitis,uveitis,or endophthalmitis,can be vision-threateni...Red eye affects patients of all ages and is one of the most common ocular complaints seen in primary care and emergency rooms.Some conditions,like scleritis,keratitis,uveitis,or endophthalmitis,can be vision-threatening and necessitate an immediate diagnosis and referral,but many others,like conjunctivitis or episcleritis,are benign and self-limiting.To prevent complications,such as irreversible vision loss or the spread of infection throughout the body,it is essential to accurately and promptly distinguish between benign and serious causes.With a broad range of etiologies covered,this review offers a thorough,evidence-based method for assessing red eye in primary care.For inflammatory,infectious,traumatic,and non-inflammatory disorders,we look at important clinical characteristics,diagnostic factors,and therapeutic approaches.Dry eye syndrome,pterygium,scleritis,episcleritis,keratitis,conjunctivitis,uveitis,blepharitis,hordeolum,endophthalmitis,orbital cellulitis,hyphema,trichiasis,and subconjunctival hemorrhage are among them.Whereas episcleritis usually responds to topical treatment,inflammatory conditions like scleritis and uveitis need systemic corticosteroids or immunosuppressive therapy.Infections such as keratitis,conjunctivitis,and endophthalmitis require treatments specific to the pathogen,while diseases like orbital cellulitis and hyphema may require hospitalization or surgery.External conditions like dry eye and blepharitis are treated conservatively with lubrication and cleanliness.This review aims to provide general practitioners with useful clinical tools for timely assessment,efficient triage,and referral by defining red flag symptoms,hallmark signs,and updated treatment protocols.Regular eye exams and patient education also improve results and lower recurrence.展开更多
AIM:To investigate the factors influencing meibomian gland atrophy(MGA)in children with allergic conjunctivitis(AC).METHODS:In this cross-sectional study,60 children with AC aged 6-17y and 20 age-matched children with...AIM:To investigate the factors influencing meibomian gland atrophy(MGA)in children with allergic conjunctivitis(AC).METHODS:In this cross-sectional study,60 children with AC aged 6-17y and 20 age-matched children without signs or symptoms of ocular surface dysfunction were included.Information on the duration of AC,untreated time,electronic screen time(EST),outdoor exercise time,body mass index(BMI),and frequency of eye rubbing was collected using a health history form.The Standard Patient Evaluation of Eye Dryness(SPEED)score was used for dry eye assessment.Images of the meibomian glands(MGs)were obtained using Keratograph 5M,and the rate of meibomian gland atrophy(MGAR)was calculated using Image J.All subjects underwent routine eye examinations.RESULTS:The average age of the AC group was 10.43±2.75y(range 6-17y)and 10.35±3.42y(range 6-14y)in the control group.The MGAR in the AC group was 33.42%±11.91%,significantly higher than that in the control group(18.10%±11.74%,P<0.001).Moreover,the MGAR in younger children(aged 12 and below)was significantly higher than in older children(P<0.05).Multi-factor linear regression analysis revealed that EST non-projector was a risk factor for MGAR(β=0.332,95%CI 0.04-0.22,P=0.004),while outdoor exercise time was a protective factor against MGAR(β=-0.407,95%CI-0.39 to-0.10,P=0.001).The untreated time of AC was identified as a risk factor for MGAR(β=0.24,95%CI 0.07-1.98,P=0.037),and the frequency of eye rubbing was associated with MG distortion score(P=0.00).CONCLUSION:Children with AC exhibit exacerbate MGA,with the degree of atrophy worsening as the untreated time of AC prolongs.Children under 12 years old show a higher MGAR,and EST non-projector negatively impacts MGA,while increased outdoor exercise time acts as a protective factor against MGA.展开更多
Viral infections of the ocular surface significantly contribute to morbidity and visual impairment globally.The herpes simplex virus(HSV),adenovirus,cytomegalovirus(CMV),and human papillomavirus(HPV)are predominant pa...Viral infections of the ocular surface significantly contribute to morbidity and visual impairment globally.The herpes simplex virus(HSV),adenovirus,cytomegalovirus(CMV),and human papillomavirus(HPV)are predominant pathogens impacting the cornea and conjunctiva,resulting in recurrent illness,epidemic outbreaks,and virus-associated neoplasia.Progress in virology,immunology,and molecular diagnostics has enhanced comprehension of host–virus interactions and introduced novel therapeutic opportunities.A narrative literature review was performed utilizing PubMed,Scopus,and Web of Science,encompassing papers published from 2000 to 2025,with a specific focus on research from 2020 onwards.Eligible publications were peer-reviewed clinical and experimental investigations,together with reviews that focused on epidemiology,etiology,diagnostic methodologies,and therapeutic alternatives.Research indicates that HSV keratitis is the predominant infectious cause of corneal blindness in high-income nations,although adenovirus persists in instigating epidemics of keratoconjunctivitis in the absence of licensed antiviral treatments.CMV keratitis,previously confined to immunocompromised persons,is now acknowledged in immunocompetent patients as a causative agent of corneal endotheliitis.HPV is associated with ocular surface squamous neoplasia,especially in areas with elevated ultraviolet exposure and high human immunodeficiency virus prevalence.Innovative molecular diagnostics,innovative antiviral agents,immunomodulatory approaches,and immunization initiatives signify significant progress that could enhance preventative and therapeutic results.展开更多
Data privacy leakage has always been a critical concern in cloud-based Internet of Things(IoT)systems.Dynamic Symmetric Searchable Encryption(DSSE)with forward and backward privacy aims to address this issue by enabli...Data privacy leakage has always been a critical concern in cloud-based Internet of Things(IoT)systems.Dynamic Symmetric Searchable Encryption(DSSE)with forward and backward privacy aims to address this issue by enabling updates and retrievals of ciphertext on untrusted cloud server while ensuring data privacy.However,previous research on DSSE mostly focused on single keyword search,which limits its practical application in cloud-based IoT systems.Recently,Patranabis(NDSS 2021)[1]proposed a groundbreaking DSSE scheme for conjunctive keyword search.However,this scheme fails to effectively handle deletion operations in certain circumstances,resulting in inaccurate query results.Additionally,the scheme introduces unnecessary search overhead.To overcome these problems,we present CKSE,an efficient conjunctive keyword DSSE scheme.Our scheme improves the oblivious shared computation protocol used in the scheme of Patranabis,thus enabling a more comprehensive deletion functionality.Furthermore,we introduce a state chain structure to reduce the search overhead.Through security analysis and experimental evaluation,we demonstrate that our CKSE achieves more comprehensive deletion functionality while maintaining comparable search performance and security,compared to the oblivious dynamic cross-tags protocol of Patranabis.The combination of comprehensive functionality,high efficiency,and security makes our CKSE an ideal choice for deployment in cloud-based IoT systems.展开更多
This study investigates the transmission dynamics of conjunctivitis using stochastic delay differential equations(SDDEs).A delayed stochastic model is formulated by dividing the population into five distinct compartme...This study investigates the transmission dynamics of conjunctivitis using stochastic delay differential equations(SDDEs).A delayed stochastic model is formulated by dividing the population into five distinct compartments:susceptible,exposed,infected,environmental irritants,and recovered individuals.The model undergoes thorough analytical examination,addressing key dynamical properties including positivity,boundedness,existence,and uniqueness of solutions.Local and global stability around the equilibrium points is studied with respect to the basic reproduction number.The existence of a unique global positive solution for the stochastic delayed model is established.In addition,a stochastic nonstandard finite difference scheme is developed,which is shown to be dynamically consistent and convergent toward the equilibrium states.The scheme preserves the essential qualitative features of the model and demonstrates improved performance when compared to existing numerical methods.Finally,the impact of time delays and stochastic fluctuations on the susceptible and infected populations is analyzed.展开更多
The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplane...The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere ionosphere.Combining these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE mission.Here,we describe current community efforts to prepare for SMILE,and the benefits and context various experiments that have explicitly expressed support for SMILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these efforts.Preparations include constructing an online SMILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft conjunctions.We anticipate growing interest and community engagement with the SMILE mission,and we welcome novel ideas and insights from the solar-terrestrial community.展开更多
Objective To observe the clinical efficacy of bloodletting at Erjian（耳尖EX- HN 6） combined with traditional Chinese herbal medication （heat-clearing I recipe） ultrasonic atomization in treatment of acute catarrha...Objective To observe the clinical efficacy of bloodletting at Erjian（耳尖EX- HN 6） combined with traditional Chinese herbal medication （heat-clearing I recipe） ultrasonic atomization in treatment of acute catarrhal conjunctivitis （fulminant wind and invading fever）. Method One hundred and twenty- two patients （244 eyes） were randomly divided into 3 groups. In group A （40 cases, 80 eyes）, levofloxacin hydrochloride eye drops were administrated for four times per day; in group B （42 cases, 84 eyes）, ＂heat-clearing I recipe＂ ultrasonic atomization was applied for twice per day with 20 rain for each time; and in group C （40 cases, 80 eyes）, bloodletting at EX-HN 6 was applied before ultrasonic atomization on the first 3 days of treatment, with once per day. Result （1） The total effective rate of group C was 100.00% which was significantly superior to 88.75% in group A （P〈0.05）; （2） the average course of treatment of clinical cured patients of group C was significantly shorter than those of group A and group B （P〈0.05）. Conclusion It is indicated from this study that ＂heat-clearing I recipe＂ ultrasonic atomization combined with bloodletting at EX-HN 6 in treatment of acute catarrhal conjunctivitis （fulminant wind and invading fever） have definite efficacy, its clinical efficacy is significantly superior to traditional levofloxacin treatment, and its course of treatment is obviously shorter than that of simple traditional Chinese medicine ultrasonic atomization. Cold ultrasonic atomization can effectively relieve local burning sensation, obviously relieve reddening and swelling and heat pain of patients, and ease subjective discomfort and emotional tension of patients.展开更多
Alongside organizing events as they unfold sequentially,authors employ argumentation in an attempt to debate on the events and convince the readers.This paper is intended to compare two texts from the persuasion genre...Alongside organizing events as they unfold sequentially,authors employ argumentation in an attempt to debate on the events and convince the readers.This paper is intended to compare two texts from the persuasion genre family,and observe the channels from which they demonstrate the arguments experientially,interpersonally and textually.展开更多
The effects of BCG PSN on T cell subsets and cytokines in vernal conjunctivitis were observed. The level of total IgE was quantitatively determined before and after treatment with BCG PSN by allergen diagnostic ins...The effects of BCG PSN on T cell subsets and cytokines in vernal conjunctivitis were observed. The level of total IgE was quantitatively determined before and after treatment with BCG PSN by allergen diagnostic instrument in vitro . The content of T cell subsets of peripheral blood and cytokine were determined by using indirect immune fluorescence method, and IL 4 and INF γ were quantified by ELISA. The results showed that the level of total IgE was substantially reduced ( P <0.01) after treatment in the BCG PSN group. Meanwhile, CD + 8 was decreased, CD + 4 and CD + 4/CD + 8 ratio elevated with significant differences ( P <0.05) as compared with pre treatment results. The changes in total IgE, CD + 8 ,CD + 4 and CD + 4/CD + 8 ratio after treatment also presented significant differences ( P <0.05) between BCG PSN group and routine treatment group. The level of IL 4 in serum declined ( P <0.05) after treatment in the BCG PSN group, and INF γ went up ( P <0 05). IL 4 and INF γ in serum showed significant differences ( P <0.05) between two groups after treatment. It is concluded that BCG PSN has a bi directional immunoregulating effect. It can bring CD + 4 and CD + 8 into homeostasis, thereby preventing the occurrence of anaphylaxis. At the same time, BCG PSN can restrain Th 2, decrease the synthesis of IL 4, switch the balance of Th l/Th 2 to Th 1 side, boost up the predominance of Th 1 relatively, which is propitious to perennial stabilization and recovery of vernal conjunctivitis.展开更多
AIM: To assess the efficacy of topical Semaphorin 3A(SEMA3A) in the treatment of allergic conjunctivitis.METHODS: Experimental allergic conjunctivitis(EAC)mice model induced by short ragweed pollen(SRW) in 4-week-old ...AIM: To assess the efficacy of topical Semaphorin 3A(SEMA3A) in the treatment of allergic conjunctivitis.METHODS: Experimental allergic conjunctivitis(EAC)mice model induced by short ragweed pollen(SRW) in 4-week-old of BALB/c mice, mice were evaluated using haematoxylin and eosin(H&E) staining, immunofluor-escence and light microscope photographs. Early phase took the samples in 24 h after instillation and late phase took the samples between 4 to 14 d after the start of treatment. The study use of topical SEMA3A(10 U, 100 U,1000 U) eye drops and subconjunctival injection of SEMA3 A with same concentration. For comparison, five types of allergy eyedrops were quantified using clinical characteristics.· RESULTS: Clinical score of composite ocular symptoms of the mice treated with SEMA3 A were significantly decreased both in the immediate phase and the late phase compared to those treated with commercial ophthalmic formulations and non-treatment mice. SEMA3 A treatment attenuates infiltration of eosinophils entering into conjunctiva in EAC mice. The score of eosinophil infiltration in the conjunctiva of SEMA3 A 1000 U-treated group were significantly lower than low-concentration of SEMA3 A treated groups and non-treated group. SEMA3 A treatment also suppressed T-cell proliferation in vitro and decreased serum total Ig E levels in EAC mice. Moreover, treatment of SEMA3 A suppressed Th2-related cytokines(IL-5, IL-13 and IL-4)and pro-inflammatory cytokines(IFN-γ, IL-17 and TNF-α)release, but increased regulatory cytokine IL-10 concentration in the conjunctiva of EAC mice.CONCLUSION: SEMA3 A as a biological agent, showed the beneficial activity in ocular allergic processes with the less damage to the intraocular tissue. It is expected that SEMA3 A may be contributed in patients with a more severe spectrum of refractory ocular allergic diseases including allergic conjunctivitis in the near future.展开更多
AIM: To demonstrate the effects of two different types of allergic conjunctivitis on severity of keratoconus (KC). ·METHODS: We retrospectively reviewed the medical records of 171 KC patients referred between Jun...AIM: To demonstrate the effects of two different types of allergic conjunctivitis on severity of keratoconus (KC). ·METHODS: We retrospectively reviewed the medical records of 171 KC patients referred between June 2010 and June 2011. The KC patients were divided into 3 groups as KC (group A), KC with vernal keratoconjunctivitis (VKC) (group B) and KC with allergic conjunctivitis (AC) (group C). Main outcome measures were demographic and ocular clinical features including age at presentation, gender, spherical equivalent (SE), best spectacle corrected visual acuity (BCVA), mean keratometric measurement (Km), central corneal thickness (CCT), and intraocular pressure (IOP). Groups were compared in term of study variables. · RESULTS: The median age at presentation was significantly lower in group B (P 【0.001). According to the median SE (P =0.003), BCVA(P =0.022), Km(P 【0.001), CCT (P =0.015) and Amsler-Krumeich classification (P 【 0.001), KC was more severe in group B. There was no significant difference in terms of IOP and corrected IOP among the groups (P =0.44), however there were 4 patients who had increased corrected IOP developed after topical corticosteroid use in group B. The differences among the groups persisted even after controlling for age and gender. · CONCLUSION: Our findings demonstrated a more severe KC in VKC patients despite their younger age which suggests evaluation of VKC patients as a separate group in keratoconus disease.展开更多
基金This article is a phased achievement of the 2020 research project“Research on Chinese-Russian Translation of Political Terminology Based on Corpora”(YB2020005)by CNTERM.
文摘The assessment of translation quality in political texts is primarily based on achieving effective communication.Throughout the translation process,it is essential to not only accurately convey the original content but also effectively transform the structural mechanisms of the source language.In the translation reconstruction of political texts,various textual cohesion methods are often employed,with conjunctions serving as a primary means for semantic coherence within text units.
文摘From the study of polysemy of coordinate conjunctions, it can be found that there are grammaticalization processes from coordination to transition and from coordination to succession. It is a general evolutionary process in connective structures to go from non-specific semantic relationship to specific semantic relationship. This was caused by the cognitive tendency of approximately substituting typical functions for atypical functions.
文摘Corpus is a kind of database that may contain texts in a single language(monolingual corpus)or text data in multiple languages(multilingual corpus).Most of the words can be involved in such a database,so it is provided with significant realistic meaning for language learners.Also,the use of causality conjunction in Korean plays a more important guiding role in listening,speaking,reading and writing of Korean.However,the status with regard to the application of causality conjunction in Korean is not optimistic and the problems such as the improper use of language,lack of knowledge about conjunction by learners,short of professional Korean teaching consciousness by teachers and others are being,thereby seriously hindering the learning interests of Korean learners and educational progress.Thus,in accordance with research status at home and abroad,this paper carries out indepth analysis on the basic theory of corpus and Korean conjunction as well as the application of causality conjunction in Korean based on the corpus.And it can be found that the research on the application of causality conjunction in Korean based on corpus is with important value for both the flexible use of language and the improvement of comprehensive application ability of language.
基金National Social Science Foundation key project“Research on Functional Words in Middle Chinese and Compilation of Functional Words Dictionary in Middle Chinese”(18AYY020).
文摘The paper explored the development of successive conjunctions from Archaic Chinese to Contemporary Chinese from a macroscopic perspective.Data statistics and diachronic study method were adopted in this paper,and the results indicated that a quantity of new successive conjunctions have been produced both in Archaic Chinese and Mid-ancient Chinese,and at the same time a very large proportion of the old successive conjunctions were superseded by the new.Those which appeared in very few types of corpus and have low frequency of use are more likely to be eliminated.In Contemporary Chinese,the successive conjunction system tends to be stable and concise.
文摘The present study is a contrastive study of inter-sentence conjunctions in Chinese/English legal parallel texts. Conjunction is one of the five cohesive devices put forward by Halliday and Hasan (1976). Many scholars have applied their model of cohesion to the study of English and Chinese languages. As for the use of conjunction in Chinese and English, most scholars believe that there are more cases of conjunction in the English legal texts than in the Chinese ones because it is generally considered that Chinese is predominantly paratactic and English mainly hypotactic. Besides, up to now little detailed contrastive study has been done on conjunctions in Chinese/English non-literary texts.
文摘Language transfer is one of the most significant aspects of cross-linguistic influ-ence.It can be divided into two types:positive and negative,the beneficial and det-rimental use of one language's acquired characteristics in another.This study aims to investigate the L1(Chinese)influence on Hong Kong ESL learners'acquisition of conjunctions and whether the use of L1 has an impact on this influence.An online questionnaire combining questions about students'English learning experience and a grammatical judgement task was sent to a government-funded secondary school in Hong Kong and completed by 79 students.Evidence of both positive and negative transfer from Chinese to English was found by testing six conjunctions or conjunc-tion pairs:although...but,because...so,not only...but also,either...or,neither...nor,.and despite.The results suggest that Chinese is likely to have an impact on students'acquisition of conjunctions,and the use of Chinese in English classes can worsen negative transfer and boost positive transfer.The degree of transfer might increase when more Chinese is used in class.To alleviate the impact of Chinese transfer and to provide more effective L2 teaching,monitoring the use of L1 and regular evalua-tion might be useful.Teachers can also adjust the amount of Chinese used according to the students'English proficiency level.
文摘Linking words,also called transition words,are quite useful in English expressions.Linking words are not the same as conjunctions,although some conjunctions can function as linking words.Here's a clear explanation for English learners,followed by a wellorganized passage on the functions of linking words in writing and communication.
基金financially supported by General Scientific Research Project for Higher Education Institutions of Liaoning Provincial Department of Education(Grant No.:LJKMZ20221171)Liaoning Provincial Science and Technology Planning Joint Program(Grant No.:2024-MSLH-580).
文摘Allergic conjunctivitis is a common ocular surface condition.Although corticosteroids are potent antiinflammatory agents for its management,their use is often restricted by potential side effects.Conventional eye drops face challenges such as short retention time and poor corneal permeability,resulting in low drug bioavailability.To overcome these limitations,we developed a preservative-free synthetic high-density lipoprotein(sHDL)nanodisc eye drop containing dexamethasone palmitate.This novel formulation enhances drug stability and extends retention time on the ocular surface.In a mouse model of ovalbumin(OVA)-induced allergic conjunctivitis,the nanodisc eye drop significantly alleviated symptoms while reducing corticosteroid concentration,demonstrating excellent safety and biocompatibility.This innovative approach shows great promise for the treatment of allergic conjunctivitis and may lay the groundwork for new therapeutic strategies in anterior ocular disease management.
文摘Red eye affects patients of all ages and is one of the most common ocular complaints seen in primary care and emergency rooms.Some conditions,like scleritis,keratitis,uveitis,or endophthalmitis,can be vision-threatening and necessitate an immediate diagnosis and referral,but many others,like conjunctivitis or episcleritis,are benign and self-limiting.To prevent complications,such as irreversible vision loss or the spread of infection throughout the body,it is essential to accurately and promptly distinguish between benign and serious causes.With a broad range of etiologies covered,this review offers a thorough,evidence-based method for assessing red eye in primary care.For inflammatory,infectious,traumatic,and non-inflammatory disorders,we look at important clinical characteristics,diagnostic factors,and therapeutic approaches.Dry eye syndrome,pterygium,scleritis,episcleritis,keratitis,conjunctivitis,uveitis,blepharitis,hordeolum,endophthalmitis,orbital cellulitis,hyphema,trichiasis,and subconjunctival hemorrhage are among them.Whereas episcleritis usually responds to topical treatment,inflammatory conditions like scleritis and uveitis need systemic corticosteroids or immunosuppressive therapy.Infections such as keratitis,conjunctivitis,and endophthalmitis require treatments specific to the pathogen,while diseases like orbital cellulitis and hyphema may require hospitalization or surgery.External conditions like dry eye and blepharitis are treated conservatively with lubrication and cleanliness.This review aims to provide general practitioners with useful clinical tools for timely assessment,efficient triage,and referral by defining red flag symptoms,hallmark signs,and updated treatment protocols.Regular eye exams and patient education also improve results and lower recurrence.
基金Supported by the Natural Science Foundation of the Zhejiang Province(No.LGD22H120002).
文摘AIM:To investigate the factors influencing meibomian gland atrophy(MGA)in children with allergic conjunctivitis(AC).METHODS:In this cross-sectional study,60 children with AC aged 6-17y and 20 age-matched children without signs or symptoms of ocular surface dysfunction were included.Information on the duration of AC,untreated time,electronic screen time(EST),outdoor exercise time,body mass index(BMI),and frequency of eye rubbing was collected using a health history form.The Standard Patient Evaluation of Eye Dryness(SPEED)score was used for dry eye assessment.Images of the meibomian glands(MGs)were obtained using Keratograph 5M,and the rate of meibomian gland atrophy(MGAR)was calculated using Image J.All subjects underwent routine eye examinations.RESULTS:The average age of the AC group was 10.43±2.75y(range 6-17y)and 10.35±3.42y(range 6-14y)in the control group.The MGAR in the AC group was 33.42%±11.91%,significantly higher than that in the control group(18.10%±11.74%,P<0.001).Moreover,the MGAR in younger children(aged 12 and below)was significantly higher than in older children(P<0.05).Multi-factor linear regression analysis revealed that EST non-projector was a risk factor for MGAR(β=0.332,95%CI 0.04-0.22,P=0.004),while outdoor exercise time was a protective factor against MGAR(β=-0.407,95%CI-0.39 to-0.10,P=0.001).The untreated time of AC was identified as a risk factor for MGAR(β=0.24,95%CI 0.07-1.98,P=0.037),and the frequency of eye rubbing was associated with MG distortion score(P=0.00).CONCLUSION:Children with AC exhibit exacerbate MGA,with the degree of atrophy worsening as the untreated time of AC prolongs.Children under 12 years old show a higher MGAR,and EST non-projector negatively impacts MGA,while increased outdoor exercise time acts as a protective factor against MGA.
文摘Viral infections of the ocular surface significantly contribute to morbidity and visual impairment globally.The herpes simplex virus(HSV),adenovirus,cytomegalovirus(CMV),and human papillomavirus(HPV)are predominant pathogens impacting the cornea and conjunctiva,resulting in recurrent illness,epidemic outbreaks,and virus-associated neoplasia.Progress in virology,immunology,and molecular diagnostics has enhanced comprehension of host–virus interactions and introduced novel therapeutic opportunities.A narrative literature review was performed utilizing PubMed,Scopus,and Web of Science,encompassing papers published from 2000 to 2025,with a specific focus on research from 2020 onwards.Eligible publications were peer-reviewed clinical and experimental investigations,together with reviews that focused on epidemiology,etiology,diagnostic methodologies,and therapeutic alternatives.Research indicates that HSV keratitis is the predominant infectious cause of corneal blindness in high-income nations,although adenovirus persists in instigating epidemics of keratoconjunctivitis in the absence of licensed antiviral treatments.CMV keratitis,previously confined to immunocompromised persons,is now acknowledged in immunocompetent patients as a causative agent of corneal endotheliitis.HPV is associated with ocular surface squamous neoplasia,especially in areas with elevated ultraviolet exposure and high human immunodeficiency virus prevalence.Innovative molecular diagnostics,innovative antiviral agents,immunomodulatory approaches,and immunization initiatives signify significant progress that could enhance preventative and therapeutic results.
基金supported in part by the Major Science and Technology Projects in Yunnan Province(202202AD080013)King Khalid University for funding this work through Large Group Project under grant number RGP.2/373/45.
文摘Data privacy leakage has always been a critical concern in cloud-based Internet of Things(IoT)systems.Dynamic Symmetric Searchable Encryption(DSSE)with forward and backward privacy aims to address this issue by enabling updates and retrievals of ciphertext on untrusted cloud server while ensuring data privacy.However,previous research on DSSE mostly focused on single keyword search,which limits its practical application in cloud-based IoT systems.Recently,Patranabis(NDSS 2021)[1]proposed a groundbreaking DSSE scheme for conjunctive keyword search.However,this scheme fails to effectively handle deletion operations in certain circumstances,resulting in inaccurate query results.Additionally,the scheme introduces unnecessary search overhead.To overcome these problems,we present CKSE,an efficient conjunctive keyword DSSE scheme.Our scheme improves the oblivious shared computation protocol used in the scheme of Patranabis,thus enabling a more comprehensive deletion functionality.Furthermore,we introduce a state chain structure to reduce the search overhead.Through security analysis and experimental evaluation,we demonstrate that our CKSE achieves more comprehensive deletion functionality while maintaining comparable search performance and security,compared to the oblivious dynamic cross-tags protocol of Patranabis.The combination of comprehensive functionality,high efficiency,and security makes our CKSE an ideal choice for deployment in cloud-based IoT systems.
基金supported by Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2025R899)Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabiasupported by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia(KFU252831)。
文摘This study investigates the transmission dynamics of conjunctivitis using stochastic delay differential equations(SDDEs).A delayed stochastic model is formulated by dividing the population into five distinct compartments:susceptible,exposed,infected,environmental irritants,and recovered individuals.The model undergoes thorough analytical examination,addressing key dynamical properties including positivity,boundedness,existence,and uniqueness of solutions.Local and global stability around the equilibrium points is studied with respect to the basic reproduction number.The existence of a unique global positive solution for the stochastic delayed model is established.In addition,a stochastic nonstandard finite difference scheme is developed,which is shown to be dynamically consistent and convergent toward the equilibrium states.The scheme preserves the essential qualitative features of the model and demonstrates improved performance when compared to existing numerical methods.Finally,the impact of time delays and stochastic fluctuations on the susceptible and infected populations is analyzed.
基金supported by Royal Society grant DHFR1211068funded by UKSA+14 种基金STFCSTFC grant ST/M001083/1funded by STFC grant ST/W00089X/1supported by NERC grant NE/W003309/1(E3d)funded by NERC grant NE/V000748/1support from NERC grants NE/V015133/1,NE/R016038/1(BAS magnetometers),and grants NE/R01700X/1 and NE/R015848/1(EISCAT)supported by NERC grant NE/T000937/1NSFC grants 42174208 and 41821003supported by the Research Council of Norway grant 223252PRODEX arrangement 4000123238 from the European Space Agencysupport of the AUTUMN East-West magnetometer network by the Canadian Space Agencysupported by NASA’s Heliophysics U.S.Participating Investigator Programsupport from grant NSF AGS 2027210supported by grant Dnr:2020-00106 from the Swedish National Space Agencysupported by the German Research Foundation(DFG)under number KR 4375/2-1 within SPP"Dynamic Earth"。
文摘The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere ionosphere.Combining these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE mission.Here,we describe current community efforts to prepare for SMILE,and the benefits and context various experiments that have explicitly expressed support for SMILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these efforts.Preparations include constructing an online SMILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft conjunctions.We anticipate growing interest and community engagement with the SMILE mission,and we welcome novel ideas and insights from the solar-terrestrial community.
文摘Objective To observe the clinical efficacy of bloodletting at Erjian（耳尖EX- HN 6） combined with traditional Chinese herbal medication （heat-clearing I recipe） ultrasonic atomization in treatment of acute catarrhal conjunctivitis （fulminant wind and invading fever）. Method One hundred and twenty- two patients （244 eyes） were randomly divided into 3 groups. In group A （40 cases, 80 eyes）, levofloxacin hydrochloride eye drops were administrated for four times per day; in group B （42 cases, 84 eyes）, ＂heat-clearing I recipe＂ ultrasonic atomization was applied for twice per day with 20 rain for each time; and in group C （40 cases, 80 eyes）, bloodletting at EX-HN 6 was applied before ultrasonic atomization on the first 3 days of treatment, with once per day. Result （1） The total effective rate of group C was 100.00% which was significantly superior to 88.75% in group A （P〈0.05）; （2） the average course of treatment of clinical cured patients of group C was significantly shorter than those of group A and group B （P〈0.05）. Conclusion It is indicated from this study that ＂heat-clearing I recipe＂ ultrasonic atomization combined with bloodletting at EX-HN 6 in treatment of acute catarrhal conjunctivitis （fulminant wind and invading fever） have definite efficacy, its clinical efficacy is significantly superior to traditional levofloxacin treatment, and its course of treatment is obviously shorter than that of simple traditional Chinese medicine ultrasonic atomization. Cold ultrasonic atomization can effectively relieve local burning sensation, obviously relieve reddening and swelling and heat pain of patients, and ease subjective discomfort and emotional tension of patients.
文摘Alongside organizing events as they unfold sequentially,authors employ argumentation in an attempt to debate on the events and convince the readers.This paper is intended to compare two texts from the persuasion genre family,and observe the channels from which they demonstrate the arguments experientially,interpersonally and textually.
文摘The effects of BCG PSN on T cell subsets and cytokines in vernal conjunctivitis were observed. The level of total IgE was quantitatively determined before and after treatment with BCG PSN by allergen diagnostic instrument in vitro . The content of T cell subsets of peripheral blood and cytokine were determined by using indirect immune fluorescence method, and IL 4 and INF γ were quantified by ELISA. The results showed that the level of total IgE was substantially reduced ( P <0.01) after treatment in the BCG PSN group. Meanwhile, CD + 8 was decreased, CD + 4 and CD + 4/CD + 8 ratio elevated with significant differences ( P <0.05) as compared with pre treatment results. The changes in total IgE, CD + 8 ,CD + 4 and CD + 4/CD + 8 ratio after treatment also presented significant differences ( P <0.05) between BCG PSN group and routine treatment group. The level of IL 4 in serum declined ( P <0.05) after treatment in the BCG PSN group, and INF γ went up ( P <0 05). IL 4 and INF γ in serum showed significant differences ( P <0.05) between two groups after treatment. It is concluded that BCG PSN has a bi directional immunoregulating effect. It can bring CD + 4 and CD + 8 into homeostasis, thereby preventing the occurrence of anaphylaxis. At the same time, BCG PSN can restrain Th 2, decrease the synthesis of IL 4, switch the balance of Th l/Th 2 to Th 1 side, boost up the predominance of Th 1 relatively, which is propitious to perennial stabilization and recovery of vernal conjunctivitis.
基金A grant-in-aid for Scientific Research from the Japanese Ministry of Education,Culture,Sports,Science and Technology
文摘AIM: To assess the efficacy of topical Semaphorin 3A(SEMA3A) in the treatment of allergic conjunctivitis.METHODS: Experimental allergic conjunctivitis(EAC)mice model induced by short ragweed pollen(SRW) in 4-week-old of BALB/c mice, mice were evaluated using haematoxylin and eosin(H&E) staining, immunofluor-escence and light microscope photographs. Early phase took the samples in 24 h after instillation and late phase took the samples between 4 to 14 d after the start of treatment. The study use of topical SEMA3A(10 U, 100 U,1000 U) eye drops and subconjunctival injection of SEMA3 A with same concentration. For comparison, five types of allergy eyedrops were quantified using clinical characteristics.· RESULTS: Clinical score of composite ocular symptoms of the mice treated with SEMA3 A were significantly decreased both in the immediate phase and the late phase compared to those treated with commercial ophthalmic formulations and non-treatment mice. SEMA3 A treatment attenuates infiltration of eosinophils entering into conjunctiva in EAC mice. The score of eosinophil infiltration in the conjunctiva of SEMA3 A 1000 U-treated group were significantly lower than low-concentration of SEMA3 A treated groups and non-treated group. SEMA3 A treatment also suppressed T-cell proliferation in vitro and decreased serum total Ig E levels in EAC mice. Moreover, treatment of SEMA3 A suppressed Th2-related cytokines(IL-5, IL-13 and IL-4)and pro-inflammatory cytokines(IFN-γ, IL-17 and TNF-α)release, but increased regulatory cytokine IL-10 concentration in the conjunctiva of EAC mice.CONCLUSION: SEMA3 A as a biological agent, showed the beneficial activity in ocular allergic processes with the less damage to the intraocular tissue. It is expected that SEMA3 A may be contributed in patients with a more severe spectrum of refractory ocular allergic diseases including allergic conjunctivitis in the near future.
文摘AIM: To demonstrate the effects of two different types of allergic conjunctivitis on severity of keratoconus (KC). ·METHODS: We retrospectively reviewed the medical records of 171 KC patients referred between June 2010 and June 2011. The KC patients were divided into 3 groups as KC (group A), KC with vernal keratoconjunctivitis (VKC) (group B) and KC with allergic conjunctivitis (AC) (group C). Main outcome measures were demographic and ocular clinical features including age at presentation, gender, spherical equivalent (SE), best spectacle corrected visual acuity (BCVA), mean keratometric measurement (Km), central corneal thickness (CCT), and intraocular pressure (IOP). Groups were compared in term of study variables. · RESULTS: The median age at presentation was significantly lower in group B (P 【0.001). According to the median SE (P =0.003), BCVA(P =0.022), Km(P 【0.001), CCT (P =0.015) and Amsler-Krumeich classification (P 【 0.001), KC was more severe in group B. There was no significant difference in terms of IOP and corrected IOP among the groups (P =0.44), however there were 4 patients who had increased corrected IOP developed after topical corticosteroid use in group B. The differences among the groups persisted even after controlling for age and gender. · CONCLUSION: Our findings demonstrated a more severe KC in VKC patients despite their younger age which suggests evaluation of VKC patients as a separate group in keratoconus disease.
