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Influence of Cell Confluency on the Expression of the α4 Integrin Subunit of Retinal Pigment Epithelial Cells
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作者 Jean-Michel Bourget Mohib Morcos +2 位作者 Karine Zaniolo Sylvain L. Guérin Stéphanie Proulx 《Advances in Biological Chemistry》 2015年第2期73-82,共10页
Integrins are a family of transmembrane glycoproteins that mediate cell-cell and cell-extracellular matrix interactions. The integrin α4 subunit is widely expressed by cells from the immune system and its expression ... Integrins are a family of transmembrane glycoproteins that mediate cell-cell and cell-extracellular matrix interactions. The integrin α4 subunit is widely expressed by cells from the immune system and its expression by non-hematopoietic cells is scarce. In the present study, gene and protein expression of this integrin subunit was characterized in proliferating and quiescent human RPE cells. Immunofluorescent studies confirm that the α4 subunit is expressed in vitro by RPE cells, a result that has been validated by immunofluorescence and FACS analyses. The accumulation of the α4 integrin at cell-cell junctions in post-confluent RPE cell cultures negatively correlated with the level of expression of the mRNA transcript. Accordingly, transient transfection analyses reveal that the α4 promoter activity is considerably reduced when RPE cells form a confluent monolayer. Moreover, transfection of recombinant constructs bearing 5’-deletions of the α4 promoter segment allows the localization of strong negative regulatory elements on the -76 to -300 region of the α4 gene suggesting that its expression is intimately linked to the proliferative state of primary cultured RPE cells. 展开更多
关键词 Retinal PIGMENT EPITHELIUM INTEGRIN Alpha 4 SUBUNIT CELL Culture confluency PROMOTER
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Three-dimensional numerical simulation of mixing patterns at open channel confluences
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作者 Ali Aghazadegan Ali Shokri 《Water Science and Engineering》 2025年第2期236-246,共11页
Open channel confluences,where two streams or rivers converge,play a crucial role in hydraulic engineering and river dynamics.These confluences are characterized by complex hydrodynamics influenced by the discharge ra... Open channel confluences,where two streams or rivers converge,play a crucial role in hydraulic engineering and river dynamics.These confluences are characterized by complex hydrodynamics influenced by the discharge ratios of merging water bodies.This study investigated the mixing structure at open channel confluences using three-dimensional numerical modeling.A comprehensive three-dimensional numerical model was developed and validated against a dataset obtained from controlled laboratory experiments.This dataset incorporated three-dimensional time-averaged velocity measurements.The skew-induced and stress-induced equation systems were adopted as the core governing equations,providing a framework for simulating various scenarios.A total of ten different cases were analyzed.The results highlighted the effect of discharge ratios on turbulence,lateral and vertical vorticities,and the distribution of mixing,which intensified with higher magnitudes of discharge ratios.The mixing structure,driven by velocity gradients and vorticity,revealed the significant role of lateral and vertical vorticities in determining hydrodynamic behaviors and mixing distributions at confluences.Specifically,the momentum ratio of incoming flows governed the spatial evolution of mixing processes.This study revealed that the distribution of mixing served as a key indicator for identifying the formation of mid-channel scours.High normalized velocities induced toward the left bank led to the superelevation of the water surface,enhancing the potential for bed material and the formation of significant scour holes beneath the elevated water surface.This novel approach provides a deeper understanding of the mixing patterns at confluences,particularly in scenarios with equilibrated discharge ratios but in different magnitudes. 展开更多
关键词 CONFLUENCE Mixing pattern Numerical modelling Transverse vorticity Vertical vorticity
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Dynamics and energetics of semidiurnal internal tides in the Weddell-Scotia Confluence
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作者 Wenjia Min Qun Li +4 位作者 Zhiliang Liu Bo Zhao Yue Ma Hang Chang Weidong Wang 《Acta Oceanologica Sinica》 2025年第3期117-129,共13页
We use a high-resolution numerical simulation to analyze the generation and evolution of semidiurnal internal tides in the Weddell-Scotia Confluence.Our results indicate that two ridges near the Antarctic Peninsula,th... We use a high-resolution numerical simulation to analyze the generation and evolution of semidiurnal internal tides in the Weddell-Scotia Confluence.Our results indicate that two ridges near the Antarctic Peninsula,the South Scotia Ridge(SSR)and the Philip Ridge(PR),are energetic sources of semidiurnal internal tides.The strongest semidiurnal barotropic to baroclinic energy conversion occurs around the crest of the SSR,reaching 0.3 W/m^(2).The depthintegrated,tidally averaged semidiurnal internal tide energy fluxes that radiated from the SSR reach about 2 kW/m.The northward semidiurnal internal tide energy fluxes entering the Scotia Sea are stronger than the southward energy fluxes entering the Powell Basin.For the SSR region between the South Orkney Plateau and Elephant Island,the areaintegrated barotropic to baroclinic conversion rate is 0.71 GW,of which 0.56 GW(79%)dissipates locally.The dissipation of internal tides occurs mainly in water depths of less than 1000 m.The dissipation rate over the SSR is as high as 10−7 W/kg.The energy fluxes create an anticlockwise gyre between the SSR and PR.The horizontal kinetic energy and available potential energy oscillate sinusoidally with peaks occurring at quarter-wavelength intervals.This energy pattern suggests the formation of standing waves due to interference between the semidiurnal internal tides originating from the SSR and PR.The results of this study show that internal tides and related mixing need to be considered in the analysis of water mass transformation in the Southern Ocean. 展开更多
关键词 internal tides Weddell-Scotia Confluence standing waves MITgcm
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Quantification of backwater effect in Jingjiang Reach due to confluence with Dongting Lake using a machine learning model
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作者 Hai-xin Shang Jun-qiang Xia +2 位作者 Chun-hong Hu Mei-rong Zhou Shan-shan Deng 《Water Science and Engineering》 2025年第2期187-199,共13页
The backwater effect caused by tributary inflow can significantly elevate the water level profile upstream of a confluence point.However,the influence of mainstream and confluence discharges on the backwater effect in... The backwater effect caused by tributary inflow can significantly elevate the water level profile upstream of a confluence point.However,the influence of mainstream and confluence discharges on the backwater effect in a river reach remains unclear.In this study,various hydrological data collected from the Jingjiang Reach of the Yangtze River in China were statistically analyzed to determine the backwater degree and range with three representative mainstream discharges.The results indicated that the backwater degree increased with mainstream discharge,and a positive relationship was observed between the runoff ratio and backwater degree at specific representative mainstream discharges.Following the operation of the Three Gorges Project,the backwater effect in the Jingjiang Reach diminished.For instance,mean backwater degrees for low,moderate,and high mainstream discharges were recorded as 0.83 m,1.61 m,and 2.41 m during the period from 1990 to 2002,whereas these values decreased to 0.30 m,0.95 m,and 2.08 m from 2009 to 2020.The backwater range extended upstream as mainstream discharge increased from 7000 m3/s to 30000 m3/s.Moreover,a random forest-based machine learning model was used to quantify the backwater effect with varying mainstream and confluence discharges,accounting for the impacts of mainstream discharge,confluence discharge,and channel degradation in the Jingjiang Reach.At the Jianli Hydrological Station,a decrease in mainstream discharge during flood seasons resulted in a 7%–15%increase in monthly mean backwater degree,while an increase in mainstream discharge during dry seasons led to a 1%–15%decrease in monthly mean backwater degree.Furthermore,increasing confluence discharge from Dongting Lake during June to July and September to November resulted in an 11%–42%increase in monthly mean backwater degree.Continuous channel degradation in the Jingjiang Reach contributed to a 6%–19%decrease in monthly mean backwater degree.Under the influence of these factors,the monthly mean backwater degree in 2017 varied from a decrease of 53%to an increase of 37%compared to corresponding values in 1991. 展开更多
关键词 Backwater effect Stage-discharge relationship Machine learning model Dongting Lake confluence Jingjiang reach
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Flow loss characteristics in parallel confluence sections of tunnels
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作者 Xin ZHANG Hao HE +5 位作者 Xiaofeng CHEN Yachao LI Tianhang ZHANG Yuehui WANG Kai ZHU Ke WU 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 2025年第7期666-678,共13页
The construction of bifurcated tunnels is essential to advancing urban infrastructure systems,as they conserve land,reduce carbon emissions,and optimize traffic.However,the bifurcation structure of the parallel conflu... The construction of bifurcated tunnels is essential to advancing urban infrastructure systems,as they conserve land,reduce carbon emissions,and optimize traffic.However,the bifurcation structure of the parallel confluence section of such tunnels poses significant challenges in the design and operation of the tunnel ventilation system,in terms of both the internal and external environment.In this work,the flow and loss characteristics of parallel confluence sections are studied with numerical simulations and model experiments.The influences of the confluence ratio q and the confluence angle O on the flow characteristics and loss mechanisms of the parallel confluence section are revealed theoretically.The results indicate that when q is small,the high-velocity airflow from the mainline entrains the low-speed airflow from the ramp,leading to flow separation at the upper connection between the parallel section and the gradual transition section;when q is large,the high-velocity airflow from the ramp entrains the low-speed airflow from the mainline,resulting in flow separation on the side of the confluence section adjacent to the mainline.Additionally,the mismatch between the airflow ratio Q and cross-sectional area ratio of the mainline tunnel and the ramp prior to confluence enhances the jet entrainment effect,increases the curvature of the streamline,expands the range of the flow separation area,and generates higher confluence loss coefficients|K_(13)|and|K_(23)|of the mainline and the ramp.For small q,|K_(13)|,and|K_(23)|,remain relatively constant with respect toθ,whereas for large q,both|K_(13)|and|K_(23)|decrease asθincreases.Finally,a semi-empirical formula is proposed to predict the loss coefficients for parallel bifurcated tunnels with confluence angles ranging from 5°to 15°.This study provides insights into the aerodynamic behaviour and loss mechanisms in bifurcated tunnels,offering guidelines for enhancing the efficiency of tunnel ventilation systems in tunnel-like underground infrastructure. 展开更多
关键词 Parallel bifurcated tunnel Confluence ratio Flow characteristics Loss coefficients
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Impact of channel regulation on tributary main-stem interactions in the VsetínskáBečva River
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作者 VAVERKA Lukáš ŠKARPICH Václav 《Journal of Mountain Science》 2025年第6期2053-2067,共15页
River confluences represent an integral component of the fluvial system,with the potential to disrupt downstream longitudinal trends in the main river through inputs of water,sediments,and other materials,such as wood... River confluences represent an integral component of the fluvial system,with the potential to disrupt downstream longitudinal trends in the main river through inputs of water,sediments,and other materials,such as woody debris.These various inputs at confluence zones result in a high degree of morphological and,consequently,ecological diversity.This study examines the potential relationship between the spatial characteristics of the catchment and the parameters of the confluence hydrodynamic zones(CHZs).A total of 15 tributaries and their adjacent CHZs were selected for analysis along a 50 km reach of the VsetínskáBečva River in the Javorníky and Hostýn-Vsetín Mountains in the Czech part of the Outer Western Carpathians.The VsetínskáBečva River is highly channelized,with the majority of channelization efforts involving riverbank stabilization,weirs,or grade control structures.The study hypothesized a correlation between the spatial arrangement of the channel,as indicated by the channel width symmetry ratio,and the angle between the tributary and main-stem river,and the increased morphological activity,evidenced by changes in average bed depth at the CHZs.The correlation coefficient(r)and p significance were employed to describe the relationships among the parameters.The results indicated a significant correlation between channel width and the catchment area symmetry ratio(r=0.747,p=0.001),likely influenced by channel regulation works(e.g.,channel shape or size),which are often artificially adjusted to accommodate local hydrological conditions and flood discharges for flood protection.A significant inverse correlation between channel width symmetry ratio and average main-stem channel depth was also found(r=-0.584,p=0.022). 展开更多
关键词 Mountain stream Confluence hydrodynamic zone Channelized river VsetínskáBečva River Outer Western Carpathians
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Laparoscopic micro-incision technique at cystic duct confluence for pediatric choledocholithiasis management:A case report
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作者 Guang-Bin Chen Yan-Guang Sha +3 位作者 Zhi-Lin Wang Ding-Bang Wang Rong-Mei Tang Yi-Sheng Chen 《World Journal of Gastrointestinal Surgery》 2025年第5期404-411,共8页
BACKGROUND The management of pediatric choledocholithiasis is complicated by anatomical constraints and the subsequent risks of conventional therapies requiring external drainage.This case report introduces a novel la... BACKGROUND The management of pediatric choledocholithiasis is complicated by anatomical constraints and the subsequent risks of conventional therapies requiring external drainage.This case report introduces a novel laparoscopic microincision tech-nique at the cystic duct confluence,designed to eliminate T-tube dependence,minimize ductal trauma,and expedite recovery,which are critical priorities for active children.We present this innovation to address unmet pediatric-specific surgical needs and demonstrate its feasibility as a tailored,minimally invasive solution for choledocholithiasis in children.A 12-year-old girl with a 5-year history of recurrent upper abdominal pain was diagnosed with choledocholithiasis,cholelithiasis,and biliary pancreatitis based on imaging and laboratory tests.After failed conservative management,laparo-scopic cholecystectomy with a microincision at the cystic duct confluence enabled choledochoscopic extraction of seven stones without T-tube placement.Primary closure using absorbable sutures with cystic duct confluence preserved biliary integrity.Postoperatively,liver function and amylase levels normalized by day 3,and abdominal ultrasonography confirmed no complications.The patient promptly resumed normal activity with no recurrence observed at the 16-month follow-up visit.This approach avoids external drainage,minimizes ductal manipulation,and optimizes recovery,which are key advantages for pediatric patients.CONCLUSION Microincision at the cystic duct confluence safely eliminates T-tubes,ensures stone clearance,and accelerates pediatric recovery. 展开更多
关键词 Pediatric choledocholithiasis Laparoscopic common bile duct exploration Micro-incision technique Cystic duct confluence Ductal integrity preservation Minimally invasive pediatric surgery Case report
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Distributed power conditioning unit of large-scale space solar power station 被引量:1
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作者 Xintong LI Jianwei MI +2 位作者 Yiqun ZHANG Guanheng FAN Jie DU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第8期421-434,共14页
In this paper,a multi-bus distributed Power Conditioning Unit(PCU)is proposed for the Space Solar Power Station with large scale photovoltaic(PV)array and power levels reaching MW level.In this unit,there are multiple... In this paper,a multi-bus distributed Power Conditioning Unit(PCU)is proposed for the Space Solar Power Station with large scale photovoltaic(PV)array and power levels reaching MW level.In this unit,there are multiple independent PV arrays.In each PV array,there are multiple independent PV subarrays.In this paper,a V-P droop control method with adaptive droop coefficient is proposed,which modifies the droop intercept based on the bus voltage deviation and the power per unit value of the PV array.This method ensures the accuracy of bus voltage and achieves proportional distribution of power between PV arrays based on the proposed topology structure in this paper.When the load changes or the output power of the PV array fluctuates,this method can ensure that power is distributed proportionally.The principle and control method of the proposed droop control method is analyzed in this paper.The effectiveness of the method is verified through MATLAB/Simulink simulation and experiment.Simulation and experimental results show that the proposed method can achieve power distributed proportionally when load changes and PV output power fluctuates,reduce bus voltage error caused by line impedance and differences in rated power of different PV arrays,and improve the performance of PV power generation system applied to space. 展开更多
关键词 Space Solar Power Station Photovoltaics Droop control DC confluence Power conditioning unit
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Effect of coir geotextile and geocell on ephemeral gully erosion in the Mollisol region of Northeast China
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作者 QIN Xijin SUN Yiqiu +4 位作者 ZHANG Yan GUAN Yinghui WU Hailong WANG Xinyu WANG Guangyu 《Journal of Arid Land》 SCIE CSCD 2024年第4期518-530,共13页
The unique geomorphological features and farming methods in the Mollisol region of Northeast China increase water catchment flow and aggravate the erosion of ephemeral gully(EG).Vegetation suffers from rain erosion an... The unique geomorphological features and farming methods in the Mollisol region of Northeast China increase water catchment flow and aggravate the erosion of ephemeral gully(EG).Vegetation suffers from rain erosion and damage during the growth stage,which brings serious problems to the restoration of grass in the early stage.Therefore,effects of coir geotextile and geocell on EG erosion under four confluence intensities were researched in this study.Results of the simulated water discharge erosion test showed that when the confluence strength was less than 30 L/min,geocell and coir geotextile had a good effect on controlling EG erosion,and sediment yield of geocell and coir geotextile was reduced by 25.95%–37.82%and 73.73%–88.96%,respectively.However,when confluence intensity increased to 40 L/min,protective effect of coir geotextile decreased,and sediment yield rate increased sharply by 189.03%.When confluence intensity increased to 50 L/min,the protective effect of coir geotextile was lost.On the other hand,geocell showed that the greater the flow rate,the better the protective effect.In addition,with the increase in confluence intensity,erosion pattern of coir geotextile developed from sheet erosion to intermittent fall and then to completion of main rill,and the protective effect was gradually weakened.In contrast,the protective effect of EG under geocell was gradually enhanced from the continuous rill to the intermittent rill and finally to the intermittent fall.This study shows that coir geotextile and geocell can prevent EG erosion,and the effect of geocell is better than that of coir geotextile on the surface of EG. 展开更多
关键词 GEOCELL coir geotextile ephemeral gully confluence intensity erosion control
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Effects of Serum Concentration, Synchronization Time and Confluence on the Cell-Cycle Synchronization Efficiency of Goat Fibroblasts
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作者 Van Khanh Nguyen Huong Thu Thi Vu +4 位作者 Au Thi Hoang Yen Kim Thi Pham Giang Thi Thanh Nhan Hung Phu Lai Lan Doan Pham 《Open Journal of Animal Sciences》 2024年第3期194-203,共10页
This study aims to evaluate the effect of serum concentration, synchronization time, and confluence degree on the synchronisation efficiency of goat fibroblast cycle. The results indicated that there was no difference... This study aims to evaluate the effect of serum concentration, synchronization time, and confluence degree on the synchronisation efficiency of goat fibroblast cycle. The results indicated that there was no difference in the percentage of nucleated fibroblasts in the G0/G1 stage between serum concentrations of 0.3% and 0.4% (83.89% and 82.69%, respectively, P > 0.05) as well as between serum concentrations of 0.2% and 0.5% (76.95% and 75.46%, respectively, P > 0.05). The percentage of nucleated fibroblasts in the G0/G1 stage was highest at the concentration of 0.3% and lowest in the control group (83.89% vs. 62.67%, P 0.05). The beneficial effect of high confluence was confirmed by the large percentage of nucleated fibroblasts at the G0/G1 stage. The 60% confluency was significantly lower than the 80% and 100% confluency (73.44%, 86.63%, and 87.17%, respectively, P < 0.05). The results indicate that the goat fibroblast cycle synchronization is the most effective at the serum concentration of 0.3%, 72 hours of synchronization and 100% confluency. 展开更多
关键词 Goat Fibroblast Cycle Synchronisation Serum Concentration Synchronization Time CONFLUENCE
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Context-attributed graph grammar framework for specifying visual languages
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作者 邹阳 曾晓勤 +1 位作者 韩秀清 张康 《Journal of Southeast University(English Edition)》 EI CAS 2008年第4期455-461,共7页
Since the specifications of most of the existing context-sensitive graph grammars tend to be either too intricate or not intuitive, a novel context-sensitive graph grammar formalism, called context-attributed graph gr... Since the specifications of most of the existing context-sensitive graph grammars tend to be either too intricate or not intuitive, a novel context-sensitive graph grammar formalism, called context-attributed graph grammar(CAGG), is proposed. In order to resolve the embedding problem, context information of a graph production in the CAGG is represented in the form of context attributes of the nodes involved. Moreover, several properties of a set of confluent CAGG productions are characterized, and then an algorithm based on them is developed to decide whether or not a set of productions is confluent, which provides the foundation for the design of efficient parsing algorithms. It can also be shown through the comparison of CAGG with several typical context-sensitive graph grammars that CAGG is more succinct and, at the same time, more intuitive than the others, making it more suitably and effortlessly applicable to the specification of visual languages. 展开更多
关键词 visual language graph grammar context-attributed PARSING CONFLUENCE
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Pollution control of outfall of rainwater-sewage confluence in old town
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作者 黄勇强 史凯 +1 位作者 朱艳 刘荣平 《Journal of Southeast University(English Edition)》 EI CAS 2014年第2期230-233,共4页
In order to improve water quality of middle ancient canal in Zhenjiang city a pollution control project was carried out.The research area is the middle catchment area of the ancient canal river system in the old town ... In order to improve water quality of middle ancient canal in Zhenjiang city a pollution control project was carried out.The research area is the middle catchment area of the ancient canal river system in the old town of Zhenjiang. The specific research object is the runoff of the outfall of rainwater-sewage confluence in the area. On the basis of detecting and analyzing the water yield and water quality of the runoff of rainwater-sewage confluence a combined technology which contains four independent continuous processes for lowering pollution load was developed and system equipment was established and put into operation. The processing effects of the project were monitored and analyzed.The results show that the pollution control project of outfall runoff is efficient which decreases the pollution load including chemical oxygen demand COD total phosphorus TP suspended solids SS and ammonia-nitrogen NH3-N .As a result the water environment of the ancient canal is protected. 展开更多
关键词 urban rainwater confluence of rainwater and sewage outfall rainwater runoff pollution load processing equipment
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改进YoloV5的行人检测算法 被引量:7
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作者 曹海涛 邓小颖 +3 位作者 张梦 张剑云 贺翔 朱金荣 《计算机辅助工程》 2023年第1期53-59,共7页
针对在行人行进过程中出现拥挤、遮挡、目标尺寸小所导致的行人检测精度低和效果不佳等问题,通过修改YoloV5算法的backbone特征提取网络,加入注意力机制,优化后处理阶段的目标框选定方法等改进措施,提出一种基于YoloV5算法的YoloV5-PED... 针对在行人行进过程中出现拥挤、遮挡、目标尺寸小所导致的行人检测精度低和效果不佳等问题,通过修改YoloV5算法的backbone特征提取网络,加入注意力机制,优化后处理阶段的目标框选定方法等改进措施,提出一种基于YoloV5算法的YoloV5-PED改进算法。结果表明:与YoloV5算法相比,YoloV5-PED算法的平均精度均值(mAP)提升3.8%,验证该算法检测行人时具有良好的效果。 展开更多
关键词 目标检测 行人遮挡检测 随机擦除 Res2Net 注意力机制 CONFLUENCE
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Total Deformation and its Role in Heavy Precipitation Events Associated with Deformation-Dominant Flow Patterns 被引量:16
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作者 高守亭 杨帅 +1 位作者 薛明 崔春光 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2008年第1期11-23,共13页
In this paper, it is elucidated that the total deformation (TD), defined as the square root of the sum of squared stretching deformation and squared shearing deformation, is an invariant independent of the coordinat... In this paper, it is elucidated that the total deformation (TD), defined as the square root of the sum of squared stretching deformation and squared shearing deformation, is an invariant independent of the coordinate system used. An idealized flow field is then constructed to demonstrate the confluence effect of a non-divergent and irrotational deformation field on moisture transport. To explore the characteristics and role of TD, one heavy rainfall case that occurred in the middle and lower reaches of the Yangtze River (MRYR) over China, associated with a front with shear line, is analyzed using the Weather Research and Forecasting (WRF) model output data. It is found that right before the occurrence of precipitation, the effect of the confluence induced by deformation on moisture transport provides a favorable condition for precipitation. During the precipitation, both location and orientation of the zone of large TD coincide with the confluent shear line. The rainhands are nearly parallel with, and located lightly to the south of the zones of large TD and the confluent shear line. The TD in the lower troposphere increases in value as precipitation persists. When TD approaches its maximal value, the next 6-hour precipitation reaches its peak correspondingly. A tendency equation for TD is derived. The analysis of linear correlation and RMS difference between individual terms in the total deformation equation and the sum of the terms shows that the pressure gradient plays a major role in determining the local change of total deformation. 展开更多
关键词 DEFORMATION CONFLUENCE PRECIPITATION equation
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Influence of bed elevation discordance on flow patterns and head losses in an open-channel confluence 被引量:6
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作者 Pedro Xavier Ramos Laurent Schindfessel +1 位作者 Joao Pedro Pego Tom De Mulder 《Water Science and Engineering》 EI CAS CSCD 2019年第3期235-243,共9页
Confluences play a major role in the dynamics of networks of natural and man-made open channels, and field measurements on river confluences reveal that discordance in bed elevation is common.Studies of schematized co... Confluences play a major role in the dynamics of networks of natural and man-made open channels, and field measurements on river confluences reveal that discordance in bed elevation is common.Studies of schematized confluences with a step at the interface between the tributary and the main channel bed reveal that bed elevation discordance is an important additional control for the confluence hydrodynamics.This study aimed to improve understanding of the influence of bed elevation discordance on the flow patterns and head losses in a right-angled confluence of an open channel with rectangular cross-sections.A large eddy simulation (LES)-based numerical model was set up and validated with experiments by others.Four configurations with different bed discordance ratios were investigated.The results confirm that, with increasing bed elevation discordance, the tributary streamlines at the confluence interface deviate less from the geometrical confluence angle, the extent of the recirculation zone (RZ) gets smaller, the ratio of the water depth upstream to that downstream of the confluence decreases, and the water level depression reduces.The bed elevation discordance also leads to the development of a large-scale structure in the lee of the step.Despite the appearance of the large-scale structure, the reduced extent of the RZ and associated changes in flow deflection/contraction reduce total head losses experienced by the main channel with an increase of the bed discordance ratio.It turns out that bed elevation discordance converts the lateral momentum from the tributary to streamwise momentum in the main channel more efficiently. 展开更多
关键词 Open channel CONFLUENCE BED ELEVATION DISCORDANCE Three-dimensional numerical modelling Large EDDY simulation Recirculation ZONE
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Hydrological processes of glacier and snow melting and runoff in the Urumqi River source region, eastern Tianshan Mountains, China 被引量:6
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作者 SUN Meiping YAO Xiaojun +1 位作者 LI Zhongqin ZHANG Mingjun 《Journal of Geographical Sciences》 SCIE CSCD 2015年第2期149-164,共16页
Hydrological processes were compared, with and without the influence of precipita- tion on discharge, to identify the differences between glacierized and non-glacierized catchments in the Urumqi River source region, o... Hydrological processes were compared, with and without the influence of precipita- tion on discharge, to identify the differences between glacierized and non-glacierized catchments in the Urumqi River source region, on the northern slope of the eastern Tianshan Mountains, during the melting season (May-September) in 2011. The study was based on hydrological data observed at 10-min intervals, meteorological data observed at 15-min intervals, and glacier melting and snow observations from the Empty Cirque, Zongkong, and Urumqi Glacier No.1 gauging stations. The results indicated that the discharge differed markedly among the three gauging stations. The daily discharge was more than the nightly discharge at the Glacier No.1 gauging station, which contrasted with the patterns observed at the Zongkong and Empty Cirque gauging stations. There was a clear daily variation in the discharge at the three gauging stations, with differences in the magnitude and duration of the peak discharge. When precipitation was not considered, the time-lags between the maximum discharge and the highest temperature were 1-3 h, 10-16 h, and 5-11 h at the Glacier No.l, Empty Cirque, and Zongkong gauging stations, respectively. When precipitation was taken into consideration, the corresponding time-lags were 0-1 h, 13 h, and 6-7 h, respectively. Therefore, the duration from the generation of discharge to confluence was the shortest in the glacierized catchment and the longest in the catchment where was mainly covered by snow. It was also shown that the hydrological process from the generation of discharge to confluence shortened when precipitation was considered. The factors influencing changes in the discharge among the three gauging stations were different. For Glacier No.1 station, the discharge was mainly controlled by heat conditions in the glacierized region, and the discharge displayed an accelerated growth when the temperature exceeded 5℃ in the melt season. It was found that the englacial and subglacial drainage channel of Glacier No.1 had become simpler during the past 20 years. Its weaker retardance and storage of glacier melting water resulted in rapid discharge confluence. It was also shown that the discharge curve and the time-lag between the maximum discharge and the highest temperature could be used to reveal the evolution of the drainage system and the process of glacier and snow melting at different levels of glacier coverage. 展开更多
关键词 glacier and snow melting runoff generation and confluence hydrological process Urumqi Riversource region Tianshan Mountains
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Confluence and cold shut computation based on time field in casting simulation 被引量:5
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作者 Yong-shuai Feng Dun-ming Liao Tao Chen 《China Foundry》 SCIE CAS 2021年第2期101-109,共9页
Numerical simulation technology has been widely used in the foundry industry to analyze and improve casting processes.During the casting filling process,many filling-related defects form easily at the confluences of l... Numerical simulation technology has been widely used in the foundry industry to analyze and improve casting processes.During the casting filling process,many filling-related defects form easily at the confluences of liquid metal streams.The main filling-related defects are cold shut defects.To calculate the positions of casting defects,the characteristics of liquid metal confluences were analyzed.The flow front of liquid metal was captured by the volume-of-fluid algorithm to obtain a time field,which was used to calculate the time derivatives of the liquid front position and the confluences of liquid metal streams.To distinguish small confluences from the main confluences,the concept of confluent scale was developed,which was used to filter the small confluences based on a threshold.The calculation process was demonstrated through the post-processing of numerical simulation.A "W" shaped casting and a steering wheel casting were calculated to validate the accuracy of the method developed in this study.The positions of cold shut defects were predicted by calculating the confluences of liquid metal streams.The method was proved to be practical by comparing the calculation results with the positions of cold shut defects in an end cover casting.The computation of confluences and cold shut defects can improve the analysis efficiency and provide assurance for the optimization of a casting process plan. 展开更多
关键词 numerical simulation casting defects flow front time field CONFLUENCE cold shut
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Managing injuries of hepatic duct confluence variants after major hepatobiliary surgery:An algorithmic approach 被引量:4
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作者 Georgios Fragulidis Athanasios Marinis +5 位作者 Andreas Polydorou Christos Konstantinidis Georgios Anastasopoulos John Contis Dionysios Voros Vassilios Smyrniotis 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第19期3049-3053,共5页
AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of th... AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of these injuries is proposed. METHODS:During a 6-year period 234 patients who had undergone major hepatobiliary surgery were retrospectively reviewed in order to study postoperative bile leakage. Diagnostic workup included endoscopic and magnetic retrograde cholangiopancreatography (E/MRCP), scintigraphy and fistulography. RESULTS:Thirty (12.8%) patients who developed postoperative bile leaks were identified. Endoscopic stenting and percutaneous drainage were successful in 23 patients with bile leaks from the liver cut surface. In the rest seven patients with injuries of hepatic duct confluence, biliary variations were recognized and a stepwise therapeutic approach was considered. Conservative management was successful only in 2 patients. Volume of the liver remnant and functional liver reserve as well as local sepsis were used as criteria for either resection of the corresponding liver segment or construction of a biliary-enteric anastomosis. Two deaths occurred in this group of patients with hepatic duct confluence variants (mortality rate 28.5%). CONCLUSION:Management of major biliary fistulaethat are disconnected from the mainstream of the biliary tree and related to injury of variants of the hepatic duct confluence is extremely challenging. These patients have a grave prognosis and an early surgical procedure has to be considered. 展开更多
关键词 Biliary aberrations Bile duct injury Postope-rative bile leakage Hepatic duct confluence HEPATECTOMY
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Impact of changes in precipitation pattern on food supply in a monsoon interlacing area and its mechanism:A case study of Yunnan Province 被引量:3
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作者 LIU Zhilin DING Yinping JIAO Yuanmei 《Journal of Geographical Sciences》 SCIE CSCD 2021年第10期1490-1506,共17页
Following climate change,changes in precipitation patterns and food security are major challenges faced by humans.However,research on how these changes in precipitation pattern impacts food supply is limited.This stud... Following climate change,changes in precipitation patterns and food security are major challenges faced by humans.However,research on how these changes in precipitation pattern impacts food supply is limited.This study aims to elucidate this impact and response mechanisms using precipitation data of a climate change-sensitive confluence zone of the southwest and southeast monsoons in Yunnan Province from 1988 to 2018.The results revealed that the precipitation pattern could be divided into three periods:abundant precipitation(Stage I,from 1988 to 2004),decreased precipitation(Stage II,from 2005 to 2015),and drought recovery(Stage III,from 2016 to 2018).Following the transition from Stage I to Stage II and from Stage II to Stage III,the area of precipitation changed significantly,accounting for 15.07%,13.87%,and 16.53%of Yunnan’s total area,for Stages I,II,and III,respectively.At the provincial level,a significant positive correlation was observed between precipitation and food production(r=0.535,P<0.01),and the correlation coefficient between precipitation and grain yield was higher than that between precipitation and meat and milk production.Based on a precipitation–grain yield transect and breakpoint detection method,key precipitation thresholds affecting grain yield were estimated as 700 and 1500 mm,respectively;when precipitation was<700,700–1500,and≥1500 mm,the correlation coefficients between precipitation and grain yield were 0.448(P<0.01),0.370(P<0.01),and–0.229(P>0.05),respectively.Based on the precipitation thresholds,Yunnan Province can be divided into precipitation surplus,precipitation equilibrium,and precipitation deficit regions,corresponding countermeasures to stabilize grain yield were proposed for each of these regions.The threshold effect of precipitation on grain yield is controlled by molecular-level water–crop mechanisms,in which reactive oxygen species,a by-product of plant aerobic metabolism,plays a key regulatory role. 展开更多
关键词 monsoon confluence region precipitation patterns food supply influencing mechanisms Yunnan Province
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Numerical Simulation of Interaction Between Tributary Debris Flow and Main River 被引量:2
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作者 Zhang, Wanshun Cui, Peng +2 位作者 Wang, Ying Qiao, Fei Wang, Xiekang 《四川大学学报(工程科学版)》 EI CAS CSCD 北大核心 2005年第S1期75-80,共6页
Based on two-phase flow theory and shallow water flow assumption,a mathematical model is applied to simulate debris flow.The model considers a two-phase mixture of sediments and water fluid.Assuming that the sediments... Based on two-phase flow theory and shallow water flow assumption,a mathematical model is applied to simulate debris flow.The model considers a two-phase mixture of sediments and water fluid.Assuming that the sediments and the water fluid move downstream with the same velocity,the flow of the mixture is described using a two dimensional depth averaged model with a unique 2-D momentum equation and two mass balance e- quations for the mixture and the sediments,respectively.The finite volume method is used f... 展开更多
关键词 Debris flow water flow confluence theory numerical simulation
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