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An Empirical Analysis of the Effect of Text-Based Computer-Mediated Communication on Communicative Competence
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作者 王剑娜 《海外英语》 2016年第8期225-228,共4页
It has been suggested that text-based computer-mediated communication can help learners to use target language both in classrooms and in social contexts.It’s necessary to investigate the effect of text-based CMC on l... It has been suggested that text-based computer-mediated communication can help learners to use target language both in classrooms and in social contexts.It’s necessary to investigate the effect of text-based CMC on learners’communicative competence by conducting the method of systematic review.The findings implied that text-based CMC settings allowed learners to interact.The interaction provided learners with more opportunities to develop their communicative competence of target language. 展开更多
关键词 text-based computer-mediated communication(CMC) second language acquisition(SLA) communicATIVE compe
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Anonymity Effects and Implications in the Virtual Environment: From Crowd to Computer-Mediated Communication
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作者 Zuoming Wang 《Social Networking》 2018年第1期45-62,共18页
Anonymity, an important feature of computer-mediated communication (CMC), is embedded in this new technology. With the penetration of the Internet in society, many daily activities involve online interactions. Anonymi... Anonymity, an important feature of computer-mediated communication (CMC), is embedded in this new technology. With the penetration of the Internet in society, many daily activities involve online interactions. Anonymity affects both the task and social aspects of online communication including information exchange, decision making, and relationship development. This review examines the effects of anonymity on human behavior. It outlines how the prior literature has attempted to address this issue and how the Social Identity Deindividuation (SIDE) model has developed as an attempt to tackle this question. More importantly, it discusses a framework describing the multidimensions of anonymity in CMC [1], and subsequently raised five propositions inspired by this framework. Furthermore, using McLeod’s framework, this review evaluates SIDE studies with regard to their anonymity manipulations. This critique reveals possible future research directions for refining the SIDE model and better studying the effect of anonymity in virtual environment. 展开更多
关键词 ANONYMITY VIRTUAL Environment computer-mediated communication SIDE
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Analysis on Chinese/English Code-Switching in Computer-Mediated Communication Based on Meme Theory
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作者 张淳 石娟丽 《海外英语》 2011年第7X期11-14,共4页
Nowadays,computer-mediated communication(CMC) becomes one of the most convenient ways for people to connect with each other in which Chinese/English code-switching has been frequently used and widely spread.The articl... Nowadays,computer-mediated communication(CMC) becomes one of the most convenient ways for people to connect with each other in which Chinese/English code-switching has been frequently used and widely spread.The article will memeticly interpret this language phenomenon based on the authentic examples collected from various kinds of CMC,and point out that the Chinese/English code-switching in CMC is a kind of strong memeplex which includes many different strong memes,resulting in the popularity of Chinese/English code-switching in CMC. 展开更多
关键词 Chinese/English CODE-SWITCHING computer mediated communication(CMC) MEME THEORY strong MEMES
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Integrating Computer-Mediated Communication into an EAP course
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作者 Li Xiao Cao Ru-hua 《Frontiers of Education in China》 2006年第4期589-600,共12页
The development of the computer along with the widespread use of the Internet has rapidly promoted Computer-Mediated Communication(CMC)as a very important communication media,which can be used widely and effectively i... The development of the computer along with the widespread use of the Internet has rapidly promoted Computer-Mediated Communication(CMC)as a very important communication media,which can be used widely and effectively in foreign language teaching and learning.This essay tries to explore the advantages of CMC as well as its proposed application,beginning with the introduction of some concepts related to CMC.From the research history,the rationale of using CMC in foreign language learning is summarised.The context of an EAP course is introduced and some suggestions on using CMC in this course are proposed. 展开更多
关键词 computer-mediated communication(CMC) synchronous CMC asynchronous CMC English for academic purposes(EAP)
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Joint jammer selection and power optimization in covert communications against a warden with uncertain locations 被引量:1
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作者 Zhijun Han Yiqing Zhou +3 位作者 Yu Zhang Tong-Xing Zheng Ling Liu Jinglin Shi 《Digital Communications and Networks》 2025年第4期1113-1123,共11页
In covert communications,joint jammer selection and power optimization are important to improve performance.However,existing schemes usually assume a warden with a known location and perfect Channel State Information(... In covert communications,joint jammer selection and power optimization are important to improve performance.However,existing schemes usually assume a warden with a known location and perfect Channel State Information(CSI),which is difficult to achieve in practice.To be more practical,it is important to investigate covert communications against a warden with uncertain locations and imperfect CSI,which makes it difficult for legitimate transceivers to estimate the detection probability of the warden.First,the uncertainty caused by the unknown warden location must be removed,and the Optimal Detection Position(OPTDP)of the warden is derived which can provide the best detection performance(i.e.,the worst case for a covert communication).Then,to further avoid the impractical assumption of perfect CSI,the covert throughput is maximized using only the channel distribution information.Given this OPTDP based worst case for covert communications,the jammer selection,the jamming power,the transmission power,and the transmission rate are jointly optimized to maximize the covert throughput(OPTDP-JP).To solve this coupling problem,a Heuristic algorithm based on Maximum Distance Ratio(H-MAXDR)is proposed to provide a sub-optimal solution.First,according to the analysis of the covert throughput,the node with the maximum distance ratio(i.e.,the ratio of the distances from the jammer to the receiver and that to the warden)is selected as the friendly jammer(MAXDR).Then,the optimal transmission and jamming power can be derived,followed by the optimal transmission rate obtained via the bisection method.In numerical and simulation results,it is shown that although the location of the warden is unknown,by assuming the OPTDP of the warden,the proposed OPTDP-JP can always satisfy the covertness constraint.In addition,with an uncertain warden and imperfect CSI,the covert throughput provided by OPTDP-JP is 80%higher than the existing schemes when the covertness constraint is 0.9,showing the effectiveness of OPTDP-JP. 展开更多
关键词 Covert communications Uncertain warden Jammer selection Power optimization Throughput maximization
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Learning Based Interference Coordination for Maritime Communications 被引量:1
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作者 Liu Chuhuan Xiao Liang +3 位作者 Chen Yifan Li Siyao Yang Helin Lyu Zefang 《China Communications》 2025年第4期356-374,共19页
With the boom in maritime activities,the need for highly reliable maritime communication is becoming urgent,which is an important component of 5G/6G communication networks.However,the bandwidth reuse characteristic of... With the boom in maritime activities,the need for highly reliable maritime communication is becoming urgent,which is an important component of 5G/6G communication networks.However,the bandwidth reuse characteristic of 5G/6G networks will inevitably lead to severe interference,resulting in degradation in the communication performance of maritime users.In this paper,we propose a safe deep reinforcement learning based interference coordination scheme to jointly optimize the power control and bandwidth allocation in maritime communication systems,and exploit the quality-of-service requirements of users as the risk value references to evaluate the communication policies.In particular,this scheme designs a deep neural network to select the communication policies through the evaluation network and update the parameters using the target network,which improves the communication performance and speeds up the convergence rate.Moreover,the Nash equilibrium of the interference coordination game and the computational complexity of the proposed scheme are analyzed.Simulation and experimental results verify the performance gain of the proposed scheme compared with benchmarks. 展开更多
关键词 bandwidth allocation interference coordination maritime communication power control rein-forcement learning
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Advanced 6 G wireless communication technologies for intelligent high-speed railways 被引量:2
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作者 Wei Chen Bo Ai +3 位作者 Yuxuan Sun Cong Yu Bowen Zhang Chau Yuen 《High-Speed Railway》 2025年第1期78-92,共15页
The rapid expansion of railways,especially High-Speed Railways(HSRs),has drawn considerable interest from both academic and industrial sectors.To meet the future vision of smart rail communications,the rail transport ... The rapid expansion of railways,especially High-Speed Railways(HSRs),has drawn considerable interest from both academic and industrial sectors.To meet the future vision of smart rail communications,the rail transport industry must innovate in key technologies to ensure high-quality transmissions for passengers and railway operations.These systems must function effectively under high mobility conditions while prioritizing safety,ecofriendliness,comfort,transparency,predictability,and reliability.On the other hand,the proposal of 6 G wireless technology introduces new possibilities for innovation in communication technologies,which may truly realize the current vision of HSR.Therefore,this article gives a review of the current advanced 6 G wireless communication technologies for HSR,including random access and switching,channel estimation and beamforming,integrated sensing and communication,and edge computing.The main application scenarios of these technologies are reviewed,as well as their current research status and challenges,followed by an outlook on future development directions. 展开更多
关键词 High-speed railway Random access and switching Channel estimation and beamforming Integrated sensing and communication Edge computing
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Low-profile,low sidelobe array antenna with ultrawide beam coverage for UAV communication 被引量:1
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作者 Mei LI Zhiliang SHANG +2 位作者 Lin PU Ming-Chun TANG Lei ZHU 《Chinese Journal of Aeronautics》 2025年第1期444-454,共11页
This paper presents a design method to implement an antenna array characterized by ultra-wide beam coverage,low profile,and low Sidelobe Level(SLL)for the application of Unmanned Aerial Vehicle(UAV)air-to-ground commu... This paper presents a design method to implement an antenna array characterized by ultra-wide beam coverage,low profile,and low Sidelobe Level(SLL)for the application of Unmanned Aerial Vehicle(UAV)air-to-ground communication.The array consists of ten broadside-radiating,ultrawide-beamwidth elements that are cascaded by a central-symmetry series-fed network with tapered currents following Dolph-Chebyshev distribution to provide low SLL.First,an innovative design of end-fire Huygens source antenna that is compatible with metal ground is presented.A low-profile,half-mode Microstrip Patch Antenna(MPA)is utilized to serve as the magnetic dipole and a monopole is utilized to serves as the electric dipole,constructing the compact,end-fire,grounded Huygens source antenna.Then,two opposite-oriented end-fire Huygens source antennas are seamlessly integrated into a single antenna element in the form of monopole-loaded MPA to accomplish the ultrawide,broadside-radiating beam.Particular consideration has been applied into the design of series-fed network as well as antenna element to compensate the adverse coupling effects between elements on the radiation performance.Experiment indicates an ultrawide Half-Power Beamwidth(HPBW)of 161°and a low SLL of-25 dB with a high gain of 12 d Bi under a single-layer configuration.The concurrent ultrawide beamwidth and low SLL make it particularly attractive for applications of UAV air-to-ground communication. 展开更多
关键词 Array antenna Broad beam Fan beam Low sidelobe level Chebyshev synthesis UAV communication
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Integrated Scheduling of Communication,Sensing,and Control for UAV-aided FSO Systems
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作者 LU Dingshan YU Yinchang +1 位作者 SU Daopeng WANG Jinyuan 《电讯技术》 北大核心 2025年第6期892-902,共11页
Recently,unmanned aerial vehicle(UAV)-aided free-space optical(FSO)communication has attracted widespread attentions.However,most of the existing research focuses on communication performance only.The authors investig... Recently,unmanned aerial vehicle(UAV)-aided free-space optical(FSO)communication has attracted widespread attentions.However,most of the existing research focuses on communication performance only.The authors investigate the integrated scheduling of communication,sensing,and control for UAV-aided FSO communication systems.Initially,a sensing-control model is established via the control theory.Moreover,an FSO communication channel model is established by considering the effects of atmospheric loss,atmospheric turbulence,geometrical loss,and angle-of-arrival fluctuation.Then,the relationship between the motion control of the UAV and radial displacement is obtained to link the control aspect and communication aspect.Assuming that the base station has instantaneous channel state information(CSI)or statistical CSI,the thresholds of the sensing-control pattern activation are designed,respectively.Finally,an integrated scheduling scheme for performing communication,sensing,and control is proposed.Numerical results indicate that,compared with conventional time-triggered scheme,the proposed integrated scheduling scheme obtains comparable communication and control performance,but reduces the sensing consumed power by 52.46%. 展开更多
关键词 FSO communications integrated scheduling of communication sensing and control unmanned aerial vehicle(UAV)
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High-precision spot centroid positioning of high-frame-rate short-wave infrared images for satellite laser communication
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作者 FU Peng HE Dao-Gang +1 位作者 LIU Jun WANG Yue-Ming 《红外与毫米波学报》 北大核心 2025年第1期66-77,共12页
The accuracy of spot centroid positioning has a significant impact on the tracking accuracy of the system and the stability of the laser link construction.In satellite laser communication systems,the use of short-wave... The accuracy of spot centroid positioning has a significant impact on the tracking accuracy of the system and the stability of the laser link construction.In satellite laser communication systems,the use of short-wave infrared wavelengths as beacon light can reduce atmospheric absorption and signal attenuation.However,there are strong non-uniformity and blind pixels in the short-wave infrared image,which makes the image distorted and leads to the decrease of spot centroid positioning accuracy.Therefore,the high-precision localization of the spot centroid of the short-wave infrared images is of great research significance.A high-precision spot centroid positioning model for short-wave infrared is proposed to correct for non-uniformity and blind pixels in short-wave infrared images and quantify the localization errors caused by the two,further model-based localization error simulations are performed,and a novel spot centroid positioning payload for satellite laser communications has been designed using the latest 640×512 planar array InGaAs shortwave infrared detector.The experimental results show that the non-uniformity of the corrected image is reduced from 7%to 0.6%,the blind pixels rejection rate reaches 100%,the frame rate can be up to 2000 Hz,and the spot centroid localization accuracy is as high as 0.1 pixel point,which realizes high-precision spot centroid localization of high-frame-frequency short-wave infrared images. 展开更多
关键词 satellite laser communication spot centroid positioning short-wave infrared high frame rate NONUNIFORMITY
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Resource Allocation for Emergency Communications in Distribution Network Satellite Communication System
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作者 Xie Haoran Zhan Yafeng Fang Xin 《China Communications》 2025年第2期95-111,共17页
Frequent extreme disasters have led to frequent large-scale power outages in recent years.To quickly restore power,it is necessary to understand the damage information of the distribution network accurately.However,th... Frequent extreme disasters have led to frequent large-scale power outages in recent years.To quickly restore power,it is necessary to understand the damage information of the distribution network accurately.However,the public network communication system is easily damaged after disasters,causing the operation center to lose control of the distribution network.In this paper,we considered using satellites to transmit the distribution network data and focus on the resource scheduling problem of the satellite emergency communication system for the distribution network.Specifically,this paper first formulates the satellite beam-pointing problem and the accesschannel joint resource allocation problem.Then,this paper proposes the Priority-based Beam-pointing and Access-Channel joint optimization algorithm(PBAC),which uses convex optimization theory to solve the satellite beam pointing problem,and adopts the block coordinate descent method,Lagrangian dual method,and a greedy algorithm to solve the access-channel joint resource allocation problem,thereby obtaining the optimal resource scheduling scheme for the satellite network.Finally,this paper conducts comparative experiments with existing methods to verify the effec-tiveness of the proposed methods.The results show that the total weighted transmitted data of the proposed algorithm is increased by about 19.29∼26.29%compared with other algorithms. 展开更多
关键词 distribution network emergency communication resource scheduling satellite communication
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Child vaccine communication practice in promoting child immunization in the Amhara region of Ethiopia
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作者 Amlakie Nigussie Assefa Jemal Mohammed Haile Amanuel Gebru Woldearegay 《World Journal of Clinical Pediatrics》 2025年第4期348-360,共13页
BACKGROUND Child vaccination plays a great role in preventing infectious diseases in children.While Ethiopia has emphasized child vaccination,its effectiveness largely depends on efficient communication between health... BACKGROUND Child vaccination plays a great role in preventing infectious diseases in children.While Ethiopia has emphasized child vaccination,its effectiveness largely depends on efficient communication between health practitioners and mothers/caregivers.Thus,sufficient communication contributes to promoting child immunization and in turn improving child health.AIM To examine child vaccine communication practices and strategies as well as their relationship with sociodemographic characteristics of respondents in the Amhara region of Ethiopia.METHODS A quantitative cross-sectional survey was conducted using a pretested Likert scale questionnaire and distributed to 123 health workers in primary healthcare centers between April 2024 and June 2024.The data were analyzed using both descriptive and inferential statistics.RESULTS The results indicated that the most common vaccine communication activities included education and communication(mean score=24.1),vaccine data registration(mean score=8.86),and information exchange(mean score=8.3).A significant correlation was found between the implementation of interpersonal health communication principles and immunization communication training(F=341.756,P=0.000,P<0.05).However,no significant correlations were observed between age,education,work experience,and vaccine communication practices.Additionally,the study found that the application of interpersonal communication principles was associated with the perceived relevance of immunization communication(F=27.790,P=0.000,P<0.05).CONCLUSION Based on the findings the study concluded that communication practice in promoting child immunization is insufficient.To enhance vaccine acceptance,continuous immunization communication training for health workers is recommended. 展开更多
关键词 Child vaccine communication Health workers Health communication modes and strategies Vaccine communication activities
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Strategic Communications for the US Digital Infrastructure and Its Inherent Contradictions
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作者 Dai Yonghong Han Ruimeng 《Contemporary International Relations》 2025年第3期94-114,共21页
Digital infrastructure possesses dual attributes as both an international public good and a strategic communication tool for major countries. In recent years, the US has been active in the field of global digital infr... Digital infrastructure possesses dual attributes as both an international public good and a strategic communication tool for major countries. In recent years, the US has been active in the field of global digital infrastructure, showing a trend of deep coupling and mutual embedding with strategic communication. The US has built a strategic communication system for digital infrastructure. This system is designed to set the international agenda, collect information and intelligence, and deter its competitors. The system presents a three-way coherent infrastructure of a basic layer, application layer,and value layer. The mode of operation is characterized by commercial force collaboration, alliance system linkage, and global multi-domain network layout. However, to maintain its unipolar digital hegemony,the United States has over-instrumentalized its digital infrastructure and exploited and amplified the asymmetry of digital science and technology for a long period of time, which not only highlights its unilateral stance and exclusionary nature but also results in a global digital divide and trust deficit, which will pose constraints on its sustainability in the long term. 展开更多
关键词 digital infrastructure international communication strategic communication United States
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Communications in Urban Low-Altitude Drone Logistics Networks:Requirements,Solutions and Challenges
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作者 Duan Ruiyang Mao Yinian +1 位作者 Chen Jialong Song Jian 《China Communications》 2025年第9期37-47,共11页
Communications system has a signifi-cant impact on both operational safety and logisti-cal efficiency within low-altitude drone logistics net-works.Aiming at providing a systematic investiga-tion of real-world communi... Communications system has a signifi-cant impact on both operational safety and logisti-cal efficiency within low-altitude drone logistics net-works.Aiming at providing a systematic investiga-tion of real-world communication requirements and challenges encountered in Meituan UAV’s daily oper-ations,this article first introduces the operational sce-narios within current drone logistics networks and an-alyzes the related communication requirements.Then,the current communication solution and its inherent bottlenecks are elaborated.Finally,this paper explores emerging technologies and examines their application prospects in drone logistics networks. 展开更多
关键词 communication challenges communication requirements drone logistics low-altitude economy
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Call for Papers─Feature Topic Vol.23,No.2,2026 Beyond Terrestrial Infrastructure: Meteor Burst Communications for Next-Generation Emergency Communication Networks
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《China Communications》 2025年第8期I0002-I0002,共1页
Meteor Burst Communication(MBC),a niche yet revolutionary wireless communication paradigm,exploits the transient ionized trails generated by meteors ablating in Earth’s atmosphere to enable sporadic yet resilient lon... Meteor Burst Communication(MBC),a niche yet revolutionary wireless communication paradigm,exploits the transient ionized trails generated by meteors ablating in Earth’s atmosphere to enable sporadic yet resilient long-distance radio links.Known for its exceptional resilience,robustness,and sustained connectivity,MBC holds significant promise for applications in emergency communications,remote area connectivity,military/defense systems,and environmental monitoring.However,the scientific exploration and application of MBC have long been highly challenging.In particular,under the combined influence of multiple physical field factors,the channel experiences superimposed multiple random fading effects,exhibiting bursty,highly time-varying,and strongly random characteristics.This persistent technical challenge has resulted in the absence of a practical statistical channel model for MBC to date. 展开更多
关键词 wireless communication paradigmexploits earth s atmosphere Resilient Long Distance Radio Links Emergency communication Networks Meteor Burst communications emergency communicationsremote area connectivitymilitary defense transient ionized trails meteor burst communication mbc
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HF skywave communication for air-to-ground networks:A cooperative transmission framework
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作者 Yan LI Yitao XU +2 位作者 Haichao WANG Guoru DING Jiangchun Gu 《Chinese Journal of Aeronautics》 2025年第5期335-349,共15页
High-Frequency(HF)communication is widely used for long-distance transmission in remote and disaster areas.However,the dynamic nature of the ionosphere and multipath propagation in the HF channel pose significant chal... High-Frequency(HF)communication is widely used for long-distance transmission in remote and disaster areas.However,the dynamic nature of the ionosphere and multipath propagation in the HF channel pose significant challenges to designing efficient and robust communication systems.In this paper,we propose a Fixed Station(FS)and frequency matching method,as well as a power allocation method,to improve the sum-rate of air-to-ground HF communication networks.We derive optimal power allocation among users that share the same frequency,based on which a modified water-filling algorithm is used to solve the power allocation problem in multi-user scenarios,while a low-complexity algorithm is proposed to solve the integer optimization problem of frequency-FS matching.Simulation results demonstrate that the proposed algorithm outperforms the naive algorithm,indicating its effectiveness. 展开更多
关键词 High-frequency communications Frequency selection Skywave communications Wide-area coverage Resource allocation
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Outage Performance Analysis of UAV-Cooperative Vehicular Communication Systems
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作者 Liang Linlin Tian Zongkai +4 位作者 Huang Haiyan Zhang Nina Zhang Dehua Song Qipeng Li Yue 《China Communications》 2025年第8期245-256,共12页
The utilization of unmanned aerial vehicle(UAV) relays in cooperative communication has gained considerable attention in recent years.However,the current research is mostly based on fixed base stations and users,lacki... The utilization of unmanned aerial vehicle(UAV) relays in cooperative communication has gained considerable attention in recent years.However,the current research is mostly based on fixed base stations and users,lacking sufficient exploration of scenarios where communication nodes are in motion.This paper presents a multi-destination vehicle communication system based on decode-and-forward(DF)UAV relays,where source and destination vehicles are moving and an internal eavesdropper intercepts messages from UAV.The closed-form expressions for system outage probability and secrecy outage probability are derived to analyze the reliability and security of the system.Furthermore,the impact of the UAV's position,signal transmission power,and system time allocation ratio on the system's performance are also analyzed.The numerical simulation results validate the accuracy of the derived formulas and confirm the correctness of the analysis.The appropriate time allocation ratio significantly enhances the security performance of system under various environmental conditions. 展开更多
关键词 covert communication outage probability secrecy outage probability transport communication
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Dynamic Multi-Target Jamming Channel Allocation and Power Decision-Making in Wireless Communication Networks:A Multi-Agent Deep Reinforcement Learning Approach
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作者 Peng Xiang Xu Hua +4 位作者 Qi Zisen Wang Dan Zhang Yue Rao Ning Gu Wanyi 《China Communications》 2025年第5期71-91,共21页
This paper studies the problem of jamming decision-making for dynamic multiple communication links in wireless communication networks(WCNs).We propose a novel jamming channel allocation and power decision-making(JCAPD... This paper studies the problem of jamming decision-making for dynamic multiple communication links in wireless communication networks(WCNs).We propose a novel jamming channel allocation and power decision-making(JCAPD)approach based on multi-agent deep reinforcement learning(MADRL).In high-dynamic and multi-target aviation communication environments,the rapid changes in channels make it difficult for sensors to accurately capture instantaneous channel state information.This poses a challenge to make centralized jamming decisions with single-agent deep reinforcement learning(DRL)approaches.In response,we design a distributed multi-agent decision architecture(DMADA).We formulate multi-jammer resource allocation as a multiagent Markov decision process(MDP)and propose a fingerprint-based double deep Q-Network(FBDDQN)algorithm for solving it.Each jammer functions as an agent that interacts with the environment in this framework.Through the design of a reasonable reward and training mechanism,our approach enables jammers to achieve distributed cooperation,significantly improving the jamming success rate while considering jamming power cost,and reducing the transmission rate of links.Our experimental results show the FBDDQN algorithm is superior to the baseline methods. 展开更多
关键词 jamming resource allocation JCAPD MADRL wireless communication countermeasure wireless communication networks
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Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury
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作者 Shiming Li Jianfeng Li +5 位作者 Guoliang Chen Tao Lin Penghui Zhang Kuileung Tong Ningning Chen Shaoyu Liu 《Neural Regeneration Research》 SCIE CAS 2025年第11期3273-3286,共14页
We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine func... We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine function,their precise function in spinal cord injury remains unclear.To investigate the role of exosomes generated following neural stem cells necroptosis after spinal cord injury,we conducted singlecell RNA sequencing and validated that neural stem cells originate from ependymal cells and undergo necroptosis in response to spinal cord injury.Subsequently,we established an in vitro necroptosis model using neural stem cells isolated from embryonic mice aged 16-17 days and extracted exosomes.The results showed that necroptosis did not significantly impact the fundamental characteristics or number of exosomes.Transcriptome sequencing of exosomes in necroptosis group identified 108 differentially expressed messenger RNAs,104 long non-coding RNAs,720 circular RNAs,and 14 microRNAs compared with the control group.Construction of a competing endogenous RNA network identified the following hub genes:tuberous sclerosis 2(Tsc2),solute carrier family 16 member 3(Slc16a3),and forkhead box protein P1(Foxp1).Notably,a significant elevation in TSC2 expression was observed in spinal cord tissues following spinal cord injury.TSC2-positive cells were localized around SRY-box transcription factor 2-positive cells within the injury zone.Furthermore,in vitro analysis revealed increased TSC2 expression in exosomal receptor cells compared with other cells.Further assessment of cellular communication following spinal cord injury showed that Tsc2 was involved in ependymal cellular communication at 1 and 3 days post-injury through the epidermal growth factor and midkine signaling pathways.In addition,Slc16a3 participated in cellular communication in ependymal cells at 7 days post-injury via the vascular endothelial growth factor and macrophage migration inhibitory factor signaling pathways.Collectively,these findings confirm that exosomes derived from neural stem cells undergoing necroptosis play an important role in cellular communication after spinal cord injury and induce TSC2 upregulation in recipient cells. 展开更多
关键词 cellular communication competing endogenous RNA EXOSOMES Foxp1 NECROPTOSIS neural stem cells Slc16a3 spinal cord injury transcriptome sequencing Tsc2
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Opening Moves Involved in Text-based Computer-Mediated-Communication (CMC) by Chinese Adults
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作者 李莉华 《海外英语》 2011年第3X期257-258,260,共3页
The development of science and technology has made it not only possible but very convenient for people living in different parts of the world to communicate with each other, thus bringing forth a new form of communica... The development of science and technology has made it not only possible but very convenient for people living in different parts of the world to communicate with each other, thus bringing forth a new form of communication: computer-mediated communication (CMC). Text-based CMC is one of the most popular forms of CMC in which people send instant messages to others in different settings. Since this mode of interaction combines features of both the written and spoken language (Greenfield & Subrahmanyam, 2003), it's of great interest whether it follows the same sequential rule as the telephone conversation. However, compared to telephone conversations, computer-mediated communication has received much less attention, let alone text-based CMC. The existing body of literature mostly focuses on content analysis and linguistic features but neglects the sequential organization of such interaction (Paolillo, 1999; Greenfield and Subrahmanyam, 2003; Herring, 1999). In light of this, this paper examines the opening moves of instant message exchanges among Chinese adults in an attempt to find out the unique features characterizing the way they open an online chat. The framework that was chosen for data analysis was the sequential model proposed by Schegloff for American telephone openings. 展开更多
关键词 computer-mediated communication(CMC) Text-based CMC OPENING MOVES instant message exchanges on line chat sequential model
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