Previous studies have shown cost effectiveness and quality-of-life benefit of pneumatic compression therapy(PCT)for lymphedema(LE).Insurers,such as the Centers for Medicare/Medicaid(CMS),however,desire visual proof th...Previous studies have shown cost effectiveness and quality-of-life benefit of pneumatic compression therapy(PCT)for lymphedema(LE).Insurers,such as the Centers for Medicare/Medicaid(CMS),however,desire visual proof that PCT moves lymph.Near infrared fuorescence lymphatic imaging(NIRFLI)was used to visualize lymphatic anatomy and function in four subjects with primary and cancer treatment-related LE of the lower extremities before,during,and after PCT.Optically transparent and windowed PCT garments allowed visualization of lymph movement during single,1h PCT treatment sessions.Visualization revealed significant extravascular and lymphatic vascular movement of intradermally injected dye in all subjects.In one subject with sufficient patent lymphatic vessels to allow quantification of lymph pumping velocities and frequencies,these values were significantly increased during and after PCT as compared to pre-treatment values.Lymphatic contractile activity in patent lymphatic vessels occurred in concert with the sequential cycling of PCT.Direct visualization revealed increased lymphatic function,during and after PCT therapy,in all LE-affected extremities.Further studies are warranted to assess the effects of PCT pressure and sequences on lymph uptake and movement.展开更多
Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the ...Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.展开更多
[Objectives] To observe the clinical therapeutic efficacy of local hot-wet compress therapy of digestion ointment prescription on the patients with moderate and severe mastalgia. [Methods] Firstly,60 patients with mas...[Objectives] To observe the clinical therapeutic efficacy of local hot-wet compress therapy of digestion ointment prescription on the patients with moderate and severe mastalgia. [Methods] Firstly,60 patients with mastalgia were selected,and divided into the experimental group and control group( 30 cases for each group). The control group was treated with acupuncture at distal point,and the experimental group was treated with TCM local hot-wet compress therapy combined with acupuncture at distal point. Then,the clinical therapeutic efficacy of two groups was compared. [Results]The experimental group was superior to the control group in relieving the breast pain,improving emotional integral,reducing breast lumps,improving lump texture,and improving TCM syndrome integral( P < 0. 05). [Conclusions]The digestion ointment prescription local hot-wet compress therapy has a significant therapeutic effect on treatment of mastalgia and can significantly improve the breast pain symptom of patients.展开更多
Driven by the accelerating global aging population and increasing health consciousness, compression stocking market is experiencing rapid growth. According to the latest data from Grand View Research, the global compr...Driven by the accelerating global aging population and increasing health consciousness, compression stocking market is experiencing rapid growth. According to the latest data from Grand View Research, the global compression therapy market reached $4.25 billion in 2024, with medical compression stockings, as a core segment, boasting a compound annual growth rate(CAGR) of nearly 6%.展开更多
Intermittent pneumatic compression(IPC)is a noninvasive therapy choice for patients with peripheral arterial diseases,which typically inflates cuffs with a fixed compression period to facilitate peripheral perfusion.T...Intermittent pneumatic compression(IPC)is a noninvasive therapy choice for patients with peripheral arterial diseases,which typically inflates cuffs with a fixed compression period to facilitate peripheral perfusion.The fixed compression period ignores the synergistic effect between human cardiac pulsation and external inter-mittent compression,limiting the potential of IPC therapy.Meanwhile,existing IPC devices cannot directly assess peripheral perfusion in the target lower limb to provide feedback for adjusting treatment parameters and improving therapeutic efficacy.This work develops a cardiac cycle-synchronous IPC prototype,featuring an innovative flexible perfusion sensor module that enables real-time synchronization of compression with local blood perfusion distribution.By continuously monitoring peripheral perfusion distribution,the system adjusts compression timing based on real-time data,offering enhanced therapeutic efficacy compared to traditional fixed-period IPC treatments.We compare the therapeutic efficacy between an asynchronous mode and three cardiac cycle-synchronous modes.The results of on-body experiments show that the systole synchronous mode outperforms other modes,significantly improving the peripheral perfusion index(PPI)and augmentation index compared to the resting state.On the control side,the PPI had no significant difference between rest and treatment phase,which suggests that IPC treatment would not damage the peripheral blood perfusion on other body parts.The developed cardiac cycle-synchronous IPC prototype demonstrates that a good synchronization between the compression and the cardiac cycle might bring better therapeutic efficacy.The proposed prototype and the exploration of cardiac cycle-synchronous IPC therapy strategies are conducive to the development of non-invasive and intelligent therapies.展开更多
Aim:The objective of this follow-up study was to explore the barriers and facilitators to use of daytime compression among women with breast cancer related lymphedema who previously took part in a trial examining the ...Aim:The objective of this follow-up study was to explore the barriers and facilitators to use of daytime compression among women with breast cancer related lymphedema who previously took part in a trial examining the efficacy of night compression.Methods:We used a multi-methods approach involving a survey and subsequent focus group sessions.The survey questions were developed based on clinical experience and findings from the literature.Questions were framed to align with the Theoretical Domains Framework.For the focus group data,we applied an interpretive description qualitative methodology to understand participants'experiences and views on use of daytime compression.Qualitative findings were mapped to the Theoretical Domains Framework.Results:Questionnaires were completed by 48 of 52 participants.Only 15 participants(31%)reported adhering to wearing the garment for greater than 12 h each day.Better adherence was positively associated with perceived control of lymphedema(r=0.304;95%CI:0.051-0.564;P=0.021).Survey findings suggest that participants have good knowledge about the rationale for,and the benefits of,wearing the compression sleeve.Twenty-three survey respondents took part in one of the five subsequent focus group sessions.Five key themes were identified representing the primary barriers to regular use of daytime compression:discomfort,negative emotions,interference with function,social situations and visibility,and use of alternative management strategies. ;Conclusion:The findings suggest less than optimal adherence to daytime compression sleeve use.Further research is needed to explore the relative benefit of daytime compression,optimal wear times,and implementable strategies to improve adherence.展开更多
Objective:To discuss the clinical efficacy of treating lumbar muscle strain(LMS)with Tuina(Chinese therapeutic massage)plus Chinese medication hot compress.Methods:A total of 147 LMS patients were randomized into a Tu...Objective:To discuss the clinical efficacy of treating lumbar muscle strain(LMS)with Tuina(Chinese therapeutic massage)plus Chinese medication hot compress.Methods:A total of 147 LMS patients were randomized into a Tuina group,a Chinese medication hot compress group,and a combined group,each consisting of 49 cases.The Tuina group received Tuina treatment;the Chinese medication hot compress group received Chinese medication hot compress treatment;and the combined group received the forementioned two therapies alternately.The three groups of patients were assessed using the visual analog scale(VAS)and Oswestry disability index(ODI)before treatment and after 2 weeks of treatment.A 2-month follow-up was also conducted to observe the relapse rate.Results:The VAS and ODI scores dropped significantly after treatment in all three groups compared with their baseline(P<0.05),and the combined group surpassed the other two groups in comparing the ODI score(P<0.05).The 2-month follow-up showed that the combined group had the lowest relapse rate among the three groups(P<0.05).Conclusion:Compared to each therapy used alone,Tuina plus Chinese medication hot compress can relieve pain,improve daily living function,and reduce the short-term relapse rate better in treating LMS patients.展开更多
基金NIH/NCI grant U54 CA 136404 and NIH/NCI grant R01 CA201487.
文摘Previous studies have shown cost effectiveness and quality-of-life benefit of pneumatic compression therapy(PCT)for lymphedema(LE).Insurers,such as the Centers for Medicare/Medicaid(CMS),however,desire visual proof that PCT moves lymph.Near infrared fuorescence lymphatic imaging(NIRFLI)was used to visualize lymphatic anatomy and function in four subjects with primary and cancer treatment-related LE of the lower extremities before,during,and after PCT.Optically transparent and windowed PCT garments allowed visualization of lymph movement during single,1h PCT treatment sessions.Visualization revealed significant extravascular and lymphatic vascular movement of intradermally injected dye in all subjects.In one subject with sufficient patent lymphatic vessels to allow quantification of lymph pumping velocities and frequencies,these values were significantly increased during and after PCT as compared to pre-treatment values.Lymphatic contractile activity in patent lymphatic vessels occurred in concert with the sequential cycling of PCT.Direct visualization revealed increased lymphatic function,during and after PCT therapy,in all LE-affected extremities.Further studies are warranted to assess the effects of PCT pressure and sequences on lymph uptake and movement.
文摘Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.
基金Supported by Basic Scientific Research Project of Beijing University of Chinese Medicine(2015-JYB-XS166)Project of National Natural Science Foundation(3157397)+2 种基金Project of Beijing Natural Science Foundation(7162082)Beijing TCM Science and Technology Development Fund Project(JJ2015-13)Beijing Municipal Health System High-level Health Technology Talents Training Program(2015-3-113)
文摘[Objectives] To observe the clinical therapeutic efficacy of local hot-wet compress therapy of digestion ointment prescription on the patients with moderate and severe mastalgia. [Methods] Firstly,60 patients with mastalgia were selected,and divided into the experimental group and control group( 30 cases for each group). The control group was treated with acupuncture at distal point,and the experimental group was treated with TCM local hot-wet compress therapy combined with acupuncture at distal point. Then,the clinical therapeutic efficacy of two groups was compared. [Results]The experimental group was superior to the control group in relieving the breast pain,improving emotional integral,reducing breast lumps,improving lump texture,and improving TCM syndrome integral( P < 0. 05). [Conclusions]The digestion ointment prescription local hot-wet compress therapy has a significant therapeutic effect on treatment of mastalgia and can significantly improve the breast pain symptom of patients.
文摘Driven by the accelerating global aging population and increasing health consciousness, compression stocking market is experiencing rapid growth. According to the latest data from Grand View Research, the global compression therapy market reached $4.25 billion in 2024, with medical compression stockings, as a core segment, boasting a compound annual growth rate(CAGR) of nearly 6%.
基金supported by the National Key Research and Development Program of China(Grant number 2023YFC3603500)the National Natural Science Foundation of China(Grant Number 12332019 and U20A20390)the Fundamental Research Funds for the Central Universities.
文摘Intermittent pneumatic compression(IPC)is a noninvasive therapy choice for patients with peripheral arterial diseases,which typically inflates cuffs with a fixed compression period to facilitate peripheral perfusion.The fixed compression period ignores the synergistic effect between human cardiac pulsation and external inter-mittent compression,limiting the potential of IPC therapy.Meanwhile,existing IPC devices cannot directly assess peripheral perfusion in the target lower limb to provide feedback for adjusting treatment parameters and improving therapeutic efficacy.This work develops a cardiac cycle-synchronous IPC prototype,featuring an innovative flexible perfusion sensor module that enables real-time synchronization of compression with local blood perfusion distribution.By continuously monitoring peripheral perfusion distribution,the system adjusts compression timing based on real-time data,offering enhanced therapeutic efficacy compared to traditional fixed-period IPC treatments.We compare the therapeutic efficacy between an asynchronous mode and three cardiac cycle-synchronous modes.The results of on-body experiments show that the systole synchronous mode outperforms other modes,significantly improving the peripheral perfusion index(PPI)and augmentation index compared to the resting state.On the control side,the PPI had no significant difference between rest and treatment phase,which suggests that IPC treatment would not damage the peripheral blood perfusion on other body parts.The developed cardiac cycle-synchronous IPC prototype demonstrates that a good synchronization between the compression and the cardiac cycle might bring better therapeutic efficacy.The proposed prototype and the exploration of cardiac cycle-synchronous IPC therapy strategies are conducive to the development of non-invasive and intelligent therapies.
基金an Alberta Cancer Foundation Investigator Initiated Trials Grant and through funding from the Canadian Institutes of Health Research.
文摘Aim:The objective of this follow-up study was to explore the barriers and facilitators to use of daytime compression among women with breast cancer related lymphedema who previously took part in a trial examining the efficacy of night compression.Methods:We used a multi-methods approach involving a survey and subsequent focus group sessions.The survey questions were developed based on clinical experience and findings from the literature.Questions were framed to align with the Theoretical Domains Framework.For the focus group data,we applied an interpretive description qualitative methodology to understand participants'experiences and views on use of daytime compression.Qualitative findings were mapped to the Theoretical Domains Framework.Results:Questionnaires were completed by 48 of 52 participants.Only 15 participants(31%)reported adhering to wearing the garment for greater than 12 h each day.Better adherence was positively associated with perceived control of lymphedema(r=0.304;95%CI:0.051-0.564;P=0.021).Survey findings suggest that participants have good knowledge about the rationale for,and the benefits of,wearing the compression sleeve.Twenty-three survey respondents took part in one of the five subsequent focus group sessions.Five key themes were identified representing the primary barriers to regular use of daytime compression:discomfort,negative emotions,interference with function,social situations and visibility,and use of alternative management strategies. ;Conclusion:The findings suggest less than optimal adherence to daytime compression sleeve use.Further research is needed to explore the relative benefit of daytime compression,optimal wear times,and implementable strategies to improve adherence.
文摘Objective:To discuss the clinical efficacy of treating lumbar muscle strain(LMS)with Tuina(Chinese therapeutic massage)plus Chinese medication hot compress.Methods:A total of 147 LMS patients were randomized into a Tuina group,a Chinese medication hot compress group,and a combined group,each consisting of 49 cases.The Tuina group received Tuina treatment;the Chinese medication hot compress group received Chinese medication hot compress treatment;and the combined group received the forementioned two therapies alternately.The three groups of patients were assessed using the visual analog scale(VAS)and Oswestry disability index(ODI)before treatment and after 2 weeks of treatment.A 2-month follow-up was also conducted to observe the relapse rate.Results:The VAS and ODI scores dropped significantly after treatment in all three groups compared with their baseline(P<0.05),and the combined group surpassed the other two groups in comparing the ODI score(P<0.05).The 2-month follow-up showed that the combined group had the lowest relapse rate among the three groups(P<0.05).Conclusion:Compared to each therapy used alone,Tuina plus Chinese medication hot compress can relieve pain,improve daily living function,and reduce the short-term relapse rate better in treating LMS patients.
