Objective: A comparative study on immunologic effects of Composite Prescription in Mice. Methods: Youguiyin , prescription for tonifying Kidney), Sijunzi Decoction , for invigorating Spleen) and Taohong Siwu Decoction...Objective: A comparative study on immunologic effects of Composite Prescription in Mice. Methods: Youguiyin , prescription for tonifying Kidney), Sijunzi Decoction , for invigorating Spleen) and Taohong Siwu Decoction , for promoting blood circulation) were conducted in mice aged 18 months and divided into 4 groups. The above-mentioned prescriptions were given to group Ⅰ-Ⅲ respectively. Group Ⅳ was kept untreated for aged control. Another group of 3 month-old mice was selected as the adult control. Results: T-, B-lymphocyte transformation rate and OKT3 lymphocyte, subgroup in the agedcontrol group were distinctly lower than those in the adult control group. After 4 weeks treatment with different composite prescriptions, the T-, B-lymphocyte transformation rate of group Ⅱ and Ⅲ were evidently higher than those of the aged control group and OKT3 lymphocyte subgroup was distinctly lower in group Ⅰ than that of group Ⅳ. Conclusions: The prescription of tonifying Kidney acted on immunal function of aged animals in a way different from that of prescriptions for invigorating Spleen or for promoting blood circulation.展开更多
文摘Objective: A comparative study on immunologic effects of Composite Prescription in Mice. Methods: Youguiyin , prescription for tonifying Kidney), Sijunzi Decoction , for invigorating Spleen) and Taohong Siwu Decoction , for promoting blood circulation) were conducted in mice aged 18 months and divided into 4 groups. The above-mentioned prescriptions were given to group Ⅰ-Ⅲ respectively. Group Ⅳ was kept untreated for aged control. Another group of 3 month-old mice was selected as the adult control. Results: T-, B-lymphocyte transformation rate and OKT3 lymphocyte, subgroup in the agedcontrol group were distinctly lower than those in the adult control group. After 4 weeks treatment with different composite prescriptions, the T-, B-lymphocyte transformation rate of group Ⅱ and Ⅲ were evidently higher than those of the aged control group and OKT3 lymphocyte subgroup was distinctly lower in group Ⅰ than that of group Ⅳ. Conclusions: The prescription of tonifying Kidney acted on immunal function of aged animals in a way different from that of prescriptions for invigorating Spleen or for promoting blood circulation.
