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Clinical Experience with a System of Direct Componeer(Coltene/Whaledent, Switzerland) Composite Veneers.Work Difficulties and Ways of Overcoming Them
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作者 Bogdan R. Shumilovich~ Irina A. Spivakova Yulia B. Vorobieva 《Journal of Health Science》 2014年第12期604-611,共8页
A system of finished Componeer composite veneers is a unique and having no analogy in the world elaboration of the Swisscompany Coltene/Whaledent, an outcome of almost halfa century experience of the company working i... A system of finished Componeer composite veneers is a unique and having no analogy in the world elaboration of the Swisscompany Coltene/Whaledent, an outcome of almost halfa century experience of the company working in a field of composite materials.It combines the best features of direct and indirect restoration methods. The system is fulfilled of nanocomposite Synergy D6 that hashigh mechanical strength, convenience for workable consistency, color stability and a system of halftone shades, which facilitates colormatching. All this allows achieving excellent aesthetic results in minimal time. Application of an original standard scale givespossibility effectively assess optical properties of dental hard tissues and develop an implementation strategy of restoration before workstarted. Formation of Componeer form, polymerization and polishing at factory allow a practitioner fully utilize effect of"fluorescence" inherent to the material. All this allows us to position the Componeer system as a serious alternative to non-directmethods of restoration with the possibility of both high aesthetic and cosmetic reconstruction reliability. 展开更多
关键词 Caries composite direct restoration veneers componeer AESTHETIC restoration.
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Multiple Tin Compounds Modified Carbon Fibers to Construct Heterogeneous Interfaces for Corrosion Prevention and Electromagnetic Wave Absorption 被引量:1
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作者 Zhiqiang Guo Di Lan +6 位作者 Zirui Jia Zhenguo Gao Xuetao Shi Mukun He Hua Guo Guanglei Wu Pengfei Yin 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期507-527,共21页
Currently,the demand for electromagnetic wave(EMW)absorbing materials with specific functions and capable of withstanding harsh environments is becoming increasingly urgent.Multi-component interface engineering is con... Currently,the demand for electromagnetic wave(EMW)absorbing materials with specific functions and capable of withstanding harsh environments is becoming increasingly urgent.Multi-component interface engineering is considered an effective means to achieve high-efficiency EMW absorption.However,interface modulation engineering has not been fully discussed and has great potential in the field of EMW absorption.In this study,multi-component tin compound fiber composites based on carbon fiber(CF)substrate were prepared by electrospinning,hydrothermal synthesis,and high-temperature thermal reduction.By utilizing the different properties of different substances,rich heterogeneous interfaces are constructed.This effectively promotes charge transfer and enhances interfacial polarization and conduction loss.The prepared SnS/SnS_(2)/SnO_(2)/CF composites with abundant heterogeneous interfaces have and exhibit excellent EMW absorption properties at a loading of 50 wt%in epoxy resin.The minimum reflection loss(RL)is−46.74 dB and the maximum effective absorption bandwidth is 5.28 GHz.Moreover,SnS/SnS_(2)/SnO_(2)/CF epoxy composite coatings exhibited long-term corrosion resistance on Q235 steel surfaces.Therefore,this study provides an effective strategy for the design of high-efficiency EMW absorbing materials in complex and harsh environments. 展开更多
关键词 Electrostatic spinning Component regulation Heterogeneous interfaces Electromagnetic wave absorption Corrosion protection
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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy 被引量:1
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作者 Xin Zhou Dan Ma +7 位作者 Yi-Xiang He Jing Jin Hong-Lian Wang Yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li 《World Journal of Gastroenterology》 SCIE CAS 2025年第1期110-125,共16页
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.... BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway. 展开更多
关键词 Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis
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Geometric parameter identification of bridge precast box girder sections based on deep learning and computer vision 被引量:1
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作者 JIA Jingwei NI Youhao +2 位作者 MAO Jianxiao XU Yinfei WANG Hao 《Journal of Southeast University(English Edition)》 2025年第3期278-285,共8页
To overcome the limitations of low efficiency and reliance on manual processes in the measurement of geometric parameters for bridge prefabricated components,a method based on deep learning and computer vision is deve... To overcome the limitations of low efficiency and reliance on manual processes in the measurement of geometric parameters for bridge prefabricated components,a method based on deep learning and computer vision is developed to identify the geometric parameters.The study utilizes a common precast element for highway bridges as the research subject.First,edge feature points of the bridge component section are extracted from images of the precast component cross-sections by combining the Canny operator with mathematical morphology.Subsequently,a deep learning model is developed to identify the geometric parameters of the precast components using the extracted edge coordinates from the images as input and the predefined control parameters of the bridge section as output.A dataset is generated by varying the control parameters and noise levels for model training.Finally,field measurements are conducted to validate the accuracy of the developed method.The results indicate that the developed method effectively identifies the geometric parameters of bridge precast components,with an error rate maintained within 5%. 展开更多
关键词 bridge precast components section geometry parameters size identification computer vision deep learning
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Function,mechanism of action,metabolism,and commercial application of Lonicera japonica:a review 被引量:1
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作者 Xinli Yang Dan Yan 《Food Science and Human Wellness》 2025年第3期783-805,共23页
Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,includ... Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,including antiviral,antibacterial,antioxidant,hypoglycemic and lipid-lowering,and anti-inflammatory effects.This review summarizes the health effects and pharmacodynamic mechanisms of L.japonica extracts and the major active ingredients in these extracts,and the structures,metabolic process in vivo,and biotransformation processes of these compounds.In addition,the current status of the development of L.japonica-related functional foods is summarized.The aim is to provide a theoretical basis and reference for the further development and use of the active ingredients in L.japonica as functional foods for disease prevention and treatment. 展开更多
关键词 Lonicera japonica extract and functional components Health effects MECHANISMS Commercial application
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Research on multi-scale simulation and dynamic verification of high dynamic MEMS components in additive manufacturing 被引量:1
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作者 Sining Lv Hengzhen Feng +2 位作者 Wenzhong Lou Chuan Xiao Shiyi Li 《Defence Technology(防务技术)》 2025年第5期275-291,共17页
Metal Additive Manufacturing(MAM) technology has become an important means of rapid prototyping precision manufacturing of special high dynamic heterogeneous complex parts. In response to the micromechanical defects s... Metal Additive Manufacturing(MAM) technology has become an important means of rapid prototyping precision manufacturing of special high dynamic heterogeneous complex parts. In response to the micromechanical defects such as porosity issues, significant deformation, surface cracks, and challenging control of surface morphology encountered during the selective laser melting(SLM) additive manufacturing(AM) process of specialized Micro Electromechanical System(MEMS) components, multiparameter optimization and micro powder melt pool/macro-scale mechanical properties control simulation of specialized components are conducted. The optimal parameters obtained through highprecision preparation and machining of components and static/high dynamic verification are: laser power of 110 W, laser speed of 600 mm/s, laser diameter of 75 μm, and scanning spacing of 50 μm. The density of the subordinate components under this reference can reach 99.15%, the surface hardness can reach 51.9 HRA, the yield strength can reach 550 MPa, the maximum machining error of the components is 4.73%, and the average surface roughness is 0.45 μm. Through dynamic hammering and high dynamic firing verification, SLM components meet the requirements for overload resistance. The results have proven that MEM technology can provide a new means for the processing of MEMS components applied in high dynamic environments. The parameters obtained in the conclusion can provide a design basis for the additive preparation of MEMS components. 展开更多
关键词 Additive manufacturing High dynamic MEMS components Multiscale control Process optimization High dynamic verification
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Manufacturing of lithium battery toward deep-sea environment 被引量:1
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作者 Yaohua Zhao Nan Li +4 位作者 Keyu Xie Chuan Wang Sisi Zhou Xianggong Zhang Cong Ye 《International Journal of Extreme Manufacturing》 2025年第2期310-335,共26页
The operation of deep-sea underwater vehicles relies entirely on onboard batteries.However,the extreme deep-sea conditions,characterized by ultrahigh hydraulic pressure,low temperature,and seawater conductivity,pose s... The operation of deep-sea underwater vehicles relies entirely on onboard batteries.However,the extreme deep-sea conditions,characterized by ultrahigh hydraulic pressure,low temperature,and seawater conductivity,pose significant challenges for battery development.These conditions drive the need for specialized designs in deep-sea batteries,incorporating critical aspects of power generation,protection,distribution,and management.Over time,deep-sea battery technology has evolved through multiple generations,with lithium(Li)batteries emerging in recent decades as the preferred power source due to their high energy and reduced operational risks.Although the rapid progress of Li batteries has notably advanced the capabilities of underwater vehicles,critical technical issues remain unresolved.This review first systematically presents the whole picture of deep-sea battery manufacturing,focusing on Li batteries as the current mainstream solution for underwater power.It examines the key aspects of deep-sea Li battery development,including materials selection informed by electro-chemo-mechanics models,component modification and testing,and battery management systems specialized in software and hardware.Finally,it discusses the main challenges limiting the utilization of deep-sea batteries and outlines promising directions for future development.Based on the systematic reflection on deep-sea batteries and discussion on deep-sea Li batteries,this review aims to provide a research foundation for developing underwater power tailored for extreme environmental exploration. 展开更多
关键词 manufacturing of deep-sea battery Li battery materials selection component modification and test specialized battery management system
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Prediction of joint roughness coefficient via hybrid machine learning model combined with principal components analysis 被引量:1
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作者 Shijie Xie Hang Lin +2 位作者 Tianxing Ma Kang Peng Zhen Sun 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期2291-2306,共16页
Joint roughness coefficient(JRC)is the most commonly used parameter for quantifying surface roughness of rock discontinuities in practice.The system composed of multiple roughness statistical parameters to measure JRC... Joint roughness coefficient(JRC)is the most commonly used parameter for quantifying surface roughness of rock discontinuities in practice.The system composed of multiple roughness statistical parameters to measure JRC is a nonlinear system with a lot of overlapping information.In this paper,a dataset of eight roughness statistical parameters covering 112 digital joints is established.Then,the principal component analysis method is introduced to extract the significant information,which solves the information overlap problem of roughness characterization.Based on the two principal components of extracted features,the white shark optimizer algorithm was introduced to optimize the extreme gradient boosting model,and a new machine learning(ML)prediction model was established.The prediction accuracy of the new model and the other 17 models was measured using statistical metrics.The results show that the prediction result of the new model is more consistent with the real JRC value,with higher recognition accuracy and generalization ability. 展开更多
关键词 Rock discontinuities Joint roughness coefficient(JRC) Roughness characterization Principal components analysis(PCA) Machine learning
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Simultaneous identification of multiple animal-derived components in meat and meat products by using MNP marker based on high-throughput sequencing 被引量:1
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作者 Yan Yi Zhanyue Jiang +9 位作者 Lixia Ma Xiaoni Hou Lun Li Deping Ye Juanlan Du Hai Peng Guoquan Han Huaiping Li Jiangwen Tang Lihua Zhou 《Food Science and Human Wellness》 2025年第4期1566-1575,共10页
In order to save manpower and time costs,and to achieve simultaneous detection of multiple animal-derived components in meat and meat products,this study used multiple nucleotide polymorphism(MNP)marker technology bas... In order to save manpower and time costs,and to achieve simultaneous detection of multiple animal-derived components in meat and meat products,this study used multiple nucleotide polymorphism(MNP)marker technology based on the principle of high-throughput sequencing,and established a multi-locus 10 animalderived components identification method of cattle,goat,sheep,donkey,horse,chicken,duck,goose,pigeon,quail in meat and meat products.The specific loci of each species could be detected and the species could be accurately identified,including 5 loci for cattle and duck,3 loci for sheep,9 loci for chicken and horse,10 loci for goose and pigeon,6 loci for quail and 1 locus for donkey and goat,and an adulteration model was established to simulate commercially available samples.The results showed that the method established in this study had high throughput,good repeatability and accuracy,and was able to identify 10 animalderived components simultaneously with 100%repeatability accuracy.The detection limit was 0.1%(m/m)in simulated samples of chicken,duck and horse.Using the method established in this study to test commercially available samples,4 samples from 14 commercially available samples were detected to be inconsistent with the labels,of which 2 did not contain the target ingredient and 2 were adulterated with small amounts of other ingredients. 展开更多
关键词 Meat and meat products Multiple nucleotide polymorphism marker method High-throughput sequencing Animal-derived component identification
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Dip2a regulates stress susceptibility in the basolateral amygdala
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作者 Jing Li Zixuan He +4 位作者 Weitai Chai Meng Tian Huali Yu Xiaoxiao He Xiaojuan Zhu 《Neural Regeneration Research》 SCIE CAS 2025年第6期1735-1748,共14页
Dysregulation of neurotransmitter metabolism in the central nervous system contributes to mood disorders such as depression, anxiety, and post–traumatic stress disorder. Monoamines and amino acids are important types... Dysregulation of neurotransmitter metabolism in the central nervous system contributes to mood disorders such as depression, anxiety, and post–traumatic stress disorder. Monoamines and amino acids are important types of neurotransmitters. Our previous results have shown that disco-interacting protein 2 homolog A(Dip2a) knockout mice exhibit brain development disorders and abnormal amino acid metabolism in serum. This suggests that DIP2A is involved in the metabolism of amino acid–associated neurotransmitters. Therefore, we performed targeted neurotransmitter metabolomics analysis and found that Dip2a deficiency caused abnormal metabolism of tryptophan and thyroxine in the basolateral amygdala and medial prefrontal cortex. In addition, acute restraint stress induced a decrease in 5-hydroxytryptamine in the basolateral amygdala. Additionally, Dip2a was abundantly expressed in excitatory neurons of the basolateral amygdala, and deletion of Dip2a in these neurons resulted in hopelessness-like behavior in the tail suspension test. Altogether, these findings demonstrate that DIP2A in the basolateral amygdala may be involved in the regulation of stress susceptibility. This provides critical evidence implicating a role of DIP2A in affective disorders. 展开更多
关键词 5-HYDROXYTRYPTAMINE acute restraint stress basolateral amygdala CaMKII neurons DIP2A metabolomics NEUROTRANSMITTERS principal component analysis stress susceptibility TRYPTOPHAN
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The serum fascin-1 and tumor components containing this protein in patients with head and neck squamous cell carcinoma:A pilot study 被引量:1
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作者 Gelena V.Kakurina Elena E.Sereda +4 位作者 Marina N.Stakheeva Liubov Tashireva Olga V.Cheremisina Irina V.Kondakova Evgeny L.Choinzonov 《Journal of Biomedical Research》 2025年第5期534-537,I0046,I0047,共6页
Dear Editor,Local recurrence and cervical lymph node metastases are major causes of mortality in patients with head and neck squamous cell carcinoma(HNSCC).To date,none of the proposed strategies for predicting outcom... Dear Editor,Local recurrence and cervical lymph node metastases are major causes of mortality in patients with head and neck squamous cell carcinoma(HNSCC).To date,none of the proposed strategies for predicting outcomes in this disease have proven fully effective,and a comprehensive physical examination remains the primary method for early detection and monitoring of HNSCC. 展开更多
关键词 serum fascin cervical lymph node metastases tumor components comprehensive physical examination head neck squamous cell carcinoma hnscc head neck squamous cell carcinoma pilot study local recurrence
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Low-light image enhancement for UAVs guided by a light weighted map 被引量:1
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作者 BAI Xiaotong WANG Dianwei +2 位作者 FANG Jie LI Yuanqing XU Zhijie 《Optoelectronics Letters》 2025年第6期348-353,共6页
The unmanned aerial vehicle(UAV)images captured under low-light conditions are often suffering from noise and uneven illumination.To address these issues,we propose a low-light image enhancement algorithm for UAV imag... The unmanned aerial vehicle(UAV)images captured under low-light conditions are often suffering from noise and uneven illumination.To address these issues,we propose a low-light image enhancement algorithm for UAV images,which is inspired by the Retinex theory and guided by a light weighted map.Firstly,we propose a new network for reflectance component processing to suppress the noise in images.Secondly,we construct an illumination enhancement module that uses a light weighted map to guide the enhancement process.Finally,the processed reflectance and illumination components are recombined to obtain the enhancement results.Experimental results show that our method can suppress the noise in images while enhancing image brightness,and prevent over enhancement in bright regions.Code and data are available at https://gitee.com/baixiaotong2/uav-images.git. 展开更多
关键词 unmanned aerial vehicle retinex theory light weighted map reflectance component processing illumination enhancement module noise suppression unmanned aerial vehicle uav images low light image enhancement
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Role of preservation conditions on enrichment and fluidity maintenance of medium to high maturity lacustrine shale oil 被引量:1
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作者 ZHAO Wenzhi LIU Wei +9 位作者 BIAN Congsheng LIU Xianyang PU Xiugang LU Jiamin LI Yongxin LI Junhui LIU Shiju GUAN Ming FU Xiuli DONG Jin 《Petroleum Exploration and Development》 2025年第1期1-16,共16页
In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons ... In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons in source rocks of lacustrine shale,yet this aspect has received little attention.This paper,based on the case analysis,explores how preservation conditions influence the enrichment of mobile hydrocarbons in shale oil.Research showns that good preservation conditions play three key roles.(1)Ensure the retention of sufficient light hydrocarbons(C_(1)–C_(13)),medium hydrocarbons(C_(14)–C_(25))and small molecular aromatics(including 1–2 benzene rings)in the formation,which enhances the fluidity and flow of shale oil;(2)Maintain a high energy field(abnormally high pressure),thus facilitating the maximum outflow of shale oil;(3)Ensure that the retained hydrocarbons have the miscible flow condition of multi-component hydrocarbons(light hydrocarbons,medium hydrocarbons,heavy hydrocarbons,and heteroatomic compounds),so that the heavy hydrocarbons(C_(25+))and heavy components(non-hydrocarbons and asphaltenes)have improved fluidity and maximum flow capacity.In conclusion,in addition to the advantages of organic matter type,abundance,thermal maturity,and reservoir space,good preservation conditions of shale layers are essential for the formation of economically viable shale oil reservoirs,which should be incorporated into the evaluation criteria of shale oil-rich areas/segments and considered a necessary factor when selecting favorable exploration targets. 展开更多
关键词 medium-to-high maturity lacustrine shale oil mobile hydrocarbon enrichment preservation conditions stratum energy field miscible hydrocarbon component retained hydrocarbon fluidity Songliao Basin Ordos Basin Junggar Basin Bohai Bay Basin
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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats
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作者 Yunting Xiang Xiangxin Xing +6 位作者 Xuyun Hua Yuwen Zhang Xin Xue Jiajia Wu Mouxiong Zheng He Wang Jianguang Xu 《Neural Regeneration Research》 SCIE CAS 2025年第5期1495-1504,共10页
Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network lev... Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery. 展开更多
关键词 brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity
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Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats
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作者 Pengfei Wang Yuewei Bi +6 位作者 Min Li Jiazhi Chen Zhuyong Wang Huantao Wen Ming Zhou Minjie Luo Wangming Zhang 《Neural Regeneration Research》 SCIE CAS 2025年第4期1164-1177,共14页
Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Cu... Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Currently,studies have reported increased oscillation power in cases of levodopa-induced dyskinesia.However,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced dyskinesia.Furthermore,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is unclear.We found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s disease.Furthermore,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma flow.Administration of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum flow.However,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum direction.These findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia. 展开更多
关键词 aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials NEUROMODULATION Parkinson’s disease primary motor cortex
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Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts
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作者 Xiao-Long Zhou Wei-Jin Jiang +2 位作者 Ji Yu Mao-Jun Yao Yun-Tong Li 《Traditional Medicine Research》 2025年第1期73-81,共9页
Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigat... Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea extracts.Results:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid content.Gas chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted extraction.Specifically,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE extracts.In vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant activity.Conclusion:The findings suggest that extraction methods significantly influence the chemical composition and antioxidant properties of vine tea extracts.Ultrasonic-assisted extraction proved instrumental in elevating the DMY content in vine tea extracts,thereby enriching its flavor profile while maintaining its antioxidant properties. 展开更多
关键词 vine tea DIHYDROMYRICETIN ultrasonic-assisted extraction volatile aroma components
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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation
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作者 Xu Liang Ni-Hui Zhang +4 位作者 Zhi-Lai Zhan Guang-Lu Chang Yan Gao Xia Li Wen-Yuan Gao 《Traditional Medicine Research》 2025年第2期1-15,共15页
Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants h... Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants have some differences in efficacy,but the flower buds are easily confused for similar traits.In addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal roses.Therefore,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography fingerprints.Then,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large differences.Differential compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and Meigui.Results:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the samples.Through principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four groups.Partial least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavonoid glycosides,as well as phenolic acids.Eight differential components were screened out by orthogonal partial least-squares discriminant analysis and S-plot analysis.Quantitative analyses of the eight compounds,including gallic acid,ellagic acid,hyperoside,isoquercitrin,etc.,showed that Yueji was generally richer in phenolic acids and flavonoids than Meigui,and the quality of Yueji from Shandong and Hebei was better.It is worth noting that Xinjiang rose is rich in various components,which is worth focusing on more in-depth research.Conclusion:In this study,the fingerprints of Meigui and Yueji were established.The chemical components information of roses was further improved based on non-targeted metabolomics and mass spectrometry technology.At the same time,eight differential components of Meigui and Yueji were screened out and quantitatively analyzed.The research results provided a scientific basis for the quality control and rational development and utilization of Rosae Chinensis Flos and Rosae Rugosae Flos,and also laid a foundation for the study of their pharmacodynamic material basis. 展开更多
关键词 Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics CHEMOMETRICS multiple component quantification quality evaluation
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Influencing factor of the characterization and restoration of phase aberrations resulting from atmospheric turbulence based on Principal Component Analysis
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作者 WANG Jiang-pu-zhen WANG Zhi-qiang +2 位作者 ZHANG Jing-hui QIAO Chun-hong FAN Cheng-yu 《中国光学(中英文)》 北大核心 2025年第4期899-907,共9页
Restoration of phase aberrations is crucial for addressing atmospheric turbulence in light propagation.Traditional restoration algorithms based on Zernike polynomials(ZPs)often encounter challenges related to high com... Restoration of phase aberrations is crucial for addressing atmospheric turbulence in light propagation.Traditional restoration algorithms based on Zernike polynomials(ZPs)often encounter challenges related to high computational complexity and insufficient capture of high-frequency phase aberration components,so we proposed a Principal-Component-Analysis-based method for representing phase aberrations.This paper discusses the factors influencing the accuracy of restoration,mainly including the sample space size and the sampling interval of D/r_(0),on the basis of characterizing phase aberrations by Principal Components(PCs).The experimental results show that a larger D/r_(0)sampling interval can ensure the generalization ability and robustness of the principal components in the case of a limited amount of original data,which can help to achieve high-precision deployment of the model in practical applications quickly.In the environment with relatively strong turbulence in the test set of D/r_(0)=24,the use of 34 terms of PCs can improve the corrected Strehl ratio(SR)from 0.007 to 0.1585,while the Strehl ratio of the light spot after restoration using 34 terms of ZPs is only 0.0215,demonstrating almost no correction effect.The results indicate that PCs can serve as a better alternative in representing and restoring the characteristics of atmospheric turbulence induced phase aberrations.These findings pave the way to use PCs of phase aberrations with fewer terms than traditional ZPs to achieve data dimensionality reduction,and offer a reference to accelerate and stabilize the model and deep learning based adaptive optics correction. 展开更多
关键词 phase aberration atmospheric turbulence principal component analysis Zernike polynomials
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Call for Paper from Food Science and Human Wellness
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《食品科学》 北大核心 2025年第17期I0023-I0023,共1页
Food Science and Human Wellness(FSHW ISSN:2213-4530,CN10-1750/TS)publishes original research papers demonstrating the latest advancement of multidisci-plinary subjects related to food science and human health.Topics m... Food Science and Human Wellness(FSHW ISSN:2213-4530,CN10-1750/TS)publishes original research papers demonstrating the latest advancement of multidisci-plinary subjects related to food science and human health.Topics may include but not limited to:nutriology,bio-chemistry,microbiology,immunology and toxicology.Papers regarding components of food especially nutrients and non-nutrient bioactive compounds(with putative health benefits)are welcomed.FSHW aims to unveil the correlations between food science and human health through the dissemination of both fundamental and applied research outcomes worldwide. 展开更多
关键词 components food IMMUNOLOGY nutriology BIOCHEMISTRY MICROBIOLOGY unveil correlations food science huma food science human health
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Call for Papers from Food Science of Animal Products
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《肉类研究》 北大核心 2025年第7期I0018-I0018,共1页
Food Science of Animal Products(ISSN:2958-4124,e-ISSN:2958-3780)is a peer-reviewed,open access international journal that publishes the latest research fi ndings in the fi eld of animal-origin foods,involving food mat... Food Science of Animal Products(ISSN:2958-4124,e-ISSN:2958-3780)is a peer-reviewed,open access international journal that publishes the latest research fi ndings in the fi eld of animal-origin foods,involving food materials such as meat,aquatic products,milk,eggs,animal offals and edible insects.The research scope includes the quality and processing characteristics of food raw materials,the relationships of nutritional components and bioactive substances with human health,product fl avor and sensory characteristics,the control of harmful substances during processing or cooking,product preservation,storage and packaging;microorganisms and fermentation,illegal drug residues and food safety detection;authenticity identifi cation;cell-cultured meat,regulations and standards. 展开更多
关键词 productsmilkeggsanimal offals edible insectsthe animal origin foods nutritional components bioactive substances food materials MEAT quality processing characteristics
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