Objective To analyze the complications of transsphenoidal operation for pituitary adenomas. Methods Postoperative complications of 323 patients underwent transphenoidal surgery for pituitary adenoma between January 20...Objective To analyze the complications of transsphenoidal operation for pituitary adenomas. Methods Postoperative complications of 323 patients underwent transphenoidal surgery for pituitary adenoma between January 2001 and December 2009 in our department were retrospectively reviewed. Results Insipidus was the most common complication after展开更多
The effect of Radix Scutellariae treated on type 2 diabetic rats has been investigated by a liquid chromatography coupled with tandem mass spectrometry（LC-MS/MS） based urinary quantitative approach.In this research,...The effect of Radix Scutellariae treated on type 2 diabetic rats has been investigated by a liquid chromatography coupled with tandem mass spectrometry（LC-MS/MS） based urinary quantitative approach.In this research,multiple reactions monitoring mode of MS/MS in LC-MS/MS analysis was used to quantitatively analyze the concentrations of 7 endogenous compounds in urine of normal control group,type 2 diabetic model group and Radix Scutellariae-treated group,and multivariate statistical analysis was utilized for MS data processing.The above-mentioned three groups can be distinguished via pattern recognition.The obtained results indicated that Radix Scutellariae affect the urinary metabolic profiling of type 2 diabetic rats on the polyol pathway,protein glycation reaction and amino acids metabolism pathway.According to these results,Radix Scutellariae should have the pharmacological effect on preventing or delaying the onset and progression of diabetes and its complications.展开更多
A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including ...A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including 3 brace damage cases and 2 joint damage cases,were simulated by removing braces and weakening beam鈥揷olumn connections in the structure. The limited acceleration response data generated by hammer impact were used for system identification,and modal parameters were extracted by using the eigensystem realization algorithm. In the first stage,the possible damaged locations are determined by using the damage index and the characteristics of the analytical model itself,and the extent of damage for those substructures identified at stage I is estimated in the second stage by using a second-order eigen-sensitivity approximation method. The main contribution of this paper is to test the two-stage method by using the real dynamic data of a complicated spatial model structure with limited sensors. The analysis results indicate that the two-stage approach is ableto detect the location of both damage cases,only the severity of brace damage cases can be assessed,and the reasonable analytical model is critical for successful damage detection.展开更多
Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by...Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by collecting and sorting out the relevant literature, and the analysis was made with the complex network. Results: It was found that Bai Jie Zi (白芥子 Semen Sinapis Albae), Xi Xin (细辛 Herba Asari), Gan Sui (甘遂 Radix Euphorbiae Kansui) and Yan Hu Suo (延胡索 Rhizoma Corydalis) were used as the basic prescriptions of drugs, Feishu (BL 13), Dazhui (GV 14) and Shanzhong (CV 17) were selected as the basic prescription of points. Conclusion: The knowledge obtained from the complex networks on the basic prescriptions of drugs and points for point-application in summer to treat diseases with attacks in winter can provide a data support for working out operation norms and carrying on verification research.展开更多
文摘Objective To analyze the complications of transsphenoidal operation for pituitary adenomas. Methods Postoperative complications of 323 patients underwent transphenoidal surgery for pituitary adenoma between January 2001 and December 2009 in our department were retrospectively reviewed. Results Insipidus was the most common complication after
基金supported by the National Natural Science Foundation of China(No.81373952,81473537)the Jilin province science and technology development projects(No.20150311039YY)
文摘The effect of Radix Scutellariae treated on type 2 diabetic rats has been investigated by a liquid chromatography coupled with tandem mass spectrometry（LC-MS/MS） based urinary quantitative approach.In this research,multiple reactions monitoring mode of MS/MS in LC-MS/MS analysis was used to quantitatively analyze the concentrations of 7 endogenous compounds in urine of normal control group,type 2 diabetic model group and Radix Scutellariae-treated group,and multivariate statistical analysis was utilized for MS data processing.The above-mentioned three groups can be distinguished via pattern recognition.The obtained results indicated that Radix Scutellariae affect the urinary metabolic profiling of type 2 diabetic rats on the polyol pathway,protein glycation reaction and amino acids metabolism pathway.According to these results,Radix Scutellariae should have the pharmacological effect on preventing or delaying the onset and progression of diabetes and its complications.
基金supported by the National Natural Science Foundation of China (90815025, 90715032 and 50808013)
文摘A two-stage damage detection approach is proposed and experimentally demonstrated on a complicated spatial model structure with a limited number of measurements. In the experiment,five known damage patterns,including 3 brace damage cases and 2 joint damage cases,were simulated by removing braces and weakening beam鈥揷olumn connections in the structure. The limited acceleration response data generated by hammer impact were used for system identification,and modal parameters were extracted by using the eigensystem realization algorithm. In the first stage,the possible damaged locations are determined by using the damage index and the characteristics of the analytical model itself,and the extent of damage for those substructures identified at stage I is estimated in the second stage by using a second-order eigen-sensitivity approximation method. The main contribution of this paper is to test the two-stage method by using the real dynamic data of a complicated spatial model structure with limited sensors. The analysis results indicate that the two-stage approach is ableto detect the location of both damage cases,only the severity of brace damage cases can be assessed,and the reasonable analytical model is critical for successful damage detection.
基金supported by the National Basic Research Program of China (No. 2006CB504601) the National Key Technology R&D Program (No. 2008BA53B00)
文摘Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by collecting and sorting out the relevant literature, and the analysis was made with the complex network. Results: It was found that Bai Jie Zi (白芥子 Semen Sinapis Albae), Xi Xin (细辛 Herba Asari), Gan Sui (甘遂 Radix Euphorbiae Kansui) and Yan Hu Suo (延胡索 Rhizoma Corydalis) were used as the basic prescriptions of drugs, Feishu (BL 13), Dazhui (GV 14) and Shanzhong (CV 17) were selected as the basic prescription of points. Conclusion: The knowledge obtained from the complex networks on the basic prescriptions of drugs and points for point-application in summer to treat diseases with attacks in winter can provide a data support for working out operation norms and carrying on verification research.
