In this article, the relationship between the knowledge of competitors and the development of new products in the field of capital medical equipment has been investigated. In order to identify the criteria for measuri...In this article, the relationship between the knowledge of competitors and the development of new products in the field of capital medical equipment has been investigated. In order to identify the criteria for measuring competitors’ knowledge and developing new capital medical equipment products, marketing experts were interviewed and then a researcher-made questionnaire was compiled and distributed among the statistical sample of the research. Also, in order to achieve the goals of the research, a questionnaire among 100 members of the statistical community was selected, distributed and collected. To analyze the gathered data, the structural equation modeling (SEM) method was used in the SMART PLS 2 software to estimate the model and then the K-MEAN approach was used to cluster the capital medical equipment market based on the knowledge of actual and potential competitors. The results have shown that the knowledge of potential and actual competitors has a positive and significant effect on the development of new products in the capital medical equipment market. From the point of view of the knowledge of actual competitors, the market of “MRI”, “Ultrasound” and “SPECT” is grouped in the low knowledge cluster;“Pet MRI”, “CT Scan”, “Mammography”, “Radiography, Fluoroscopy and CRM”, “Pet CT”, “SPECT CT” and “Gamma Camera” markets are clustered in the medium knowledge. Finally, “Angiography” and “CBCT” markets are located in the knowledge cluster. From the perspective of knowledge of potential competitors, the market of “angiography”, “mammography”, “SPECT” and “SPECT CT” in the low knowledge cluster, “CT scan”, “radiography, fluoroscopy and CRM”, “pet CT”, “CBCT” markets in the medium knowledge cluster and “MRI”, “pet MRI”, “ultrasound” and “gamma camera” markets in the high knowledge cluster are located.展开更多
Considering China’s current economic growth, it is predictable that a surge for buying private cars will emerge around the year 2000. At that time, China will become the world’s largest automobile market. Having see...Considering China’s current economic growth, it is predictable that a surge for buying private cars will emerge around the year 2000. At that time, China will become the world’s largest automobile market. Having seen this trend, foreign automobile manufacturers are turning their eyes on China, the country with展开更多
From October 18 to 19,the final of the National University Student Standardization Olympiad 2025 was successfully held at China Jiliang University in Hangzhou City,Zhejiang Province.The final attracted over 400 attend...From October 18 to 19,the final of the National University Student Standardization Olympiad 2025 was successfully held at China Jiliang University in Hangzhou City,Zhejiang Province.The final attracted over 400 attendees,including members of the review expert group,representatives of organizing units,competitors,and instructors.展开更多
Send us your photographs and let us know what lies behind them at contacts@chinafrica.cnHighline Challenge Competitors race on slacklines at the Yellow River Ladder Cliffs Scenic Area in Yuncheng,Shanxi Province,on 16...Send us your photographs and let us know what lies behind them at contacts@chinafrica.cnHighline Challenge Competitors race on slacklines at the Yellow River Ladder Cliffs Scenic Area in Yuncheng,Shanxi Province,on 16 September.After fierce competition,Chinese athlete He Jinyi won the 100-metre sprint title.SOURCE:VCG。展开更多
Crown development is closely related to the biomass and growth rate of the tree and its width(CW)is an important covariable in growth and yield models and in forest management.To date,various CW models have been propo...Crown development is closely related to the biomass and growth rate of the tree and its width(CW)is an important covariable in growth and yield models and in forest management.To date,various CW models have been proposed.However,limited studies have explicitly focused on additive and inherent correlation of crown components and total CW as well as the influence of competition on crown radius from the corresponding direction.In this study,two model systems were used,i.e.,aggregation method system(AMS)and disaggregation method system(DMS),to develop crown width additive model systems.For calculating spatially explicit competition index(CI),four neighbor tree selection methods were evaluated.CI was decomposed into four cardinal directions and added into the model systems.Results show that the power model form was more proper for our data to fit CW growth.For each crown radius and total CW,height to the diameter at breast height(HDR)and basal area of trees larger than the subject tree(BAL)significantly contributed to the increase of prediction accuracy.The 3-m fixed radius was optimal among the four neighborhoods selection ways.After adding decomposed competition Hegyi index into model systems AMS and DMS,the prediction accuracy improved.Of the model systems evaluated,AMS based on decomposed CI provided the best performance as well as the inherent correlation and additivity properties.Our study highlighted the importance of decomposed CI in tree CW modelling for additive model systems.This study focused on methodology and could be applied to other species or stands.展开更多
The pathology of Alzheimer’s disease involves a long preclinical period,where the characteristic clinical symptoms of the changes in the brain are undetectable.During the preclinical period,homeostatic mechanisms may...The pathology of Alzheimer’s disease involves a long preclinical period,where the characteristic clinical symptoms of the changes in the brain are undetectable.During the preclinical period,homeostatic mechanisms may help prevent widespread cell death.Evidence has pointed towards selective cell death of diseased neurons playing a potentially protective role.As the disease progresses,dysregulation of signaling pathways that govern cell death contributes to neurodegeneration.Aberrant activation of the c-Jun N-terminal kinase pathway has been established in human and animal models of Alzheimer’s disease caused by amyloid-beta 42-or tau-mediated neurodegeneration.Clonal mosaic studies in Drosophila that examine amyloid-beta 42 in a subset of neurons suggest complex interplay between amyloid-beta 42-expressing and wild-type cells.This review examines the role of c-Jun N-terminal kinase signaling in the context of cell competition and short-range signaling interactions between amyloid-beta 42-expressing and wild-type neurons.Cell competition is a conserved phenomenon regulating tissue integrity by assessing the fitness of cells relative to their neighbors and eliminating suboptimal cells.Somatic clones of amyloid-beta 42 that juxtapose genetically distinct neuronal cell populations show promise for studying neurodegeneration.Generating genetic mosaics with labeled clones of amyloid-beta 42-or tau-expressing and wild-type neurons will allow us to understand how short-range signaling alterations trigger cell death in neurons and thereby contribute to the progression of Alzheimer’s disease.These approaches have the potential to uncover biomarkers for early Alzheimer’s disease detection and new therapeutic targets for intervention.展开更多
The Union Interationale de Pentathlon Moderne(UIPM)held its first Obstacle World Championships in Beijing from October 23 to 26.The global debut attracted more than 500 competitors from 30 countries and regions.
Patents are critically important for a company to protect its core business concepts and proprietary technologies. Effective patent mining in massive patent databases not only provides business enterprises with valuab...Patents are critically important for a company to protect its core business concepts and proprietary technologies. Effective patent mining in massive patent databases not only provides business enterprises with valuable insights to develop strategies for research and development, intellectual property management, and product marketing, but also helps patent offices to improve efficiency and optimize their patent examination processes. This paper describes the patent mining problem of automatically discovering core patents （i.e., novel and influential patents in a domain）. In addition, the value of core patent mining is illustrated by revealing the potential competitive relationships among companies in their core patents. The work addresses the unique patent vocabulary usage which is not considered in traditional word-based statistical methods with a topic-based temporal mining approach that quantifies a patent＇s novelty and influence through topic activeness variations. Tests of this method on real-world patent portfolios show the effectiveness of this approach over state-of-the-art methods.展开更多
Change in diplomatic parlance hints at a further warming of Sino-U.S. ties, even as differences continue If there is one word that has emerged as a keyword in Sino-U.S. relations since 2005, that is "stakeholder....Change in diplomatic parlance hints at a further warming of Sino-U.S. ties, even as differences continue If there is one word that has emerged as a keyword in Sino-U.S. relations since 2005, that is "stakeholder." It first came up in a speech last September by U.S. Deputy Secretary of State Robert Zoellick, who proposed that China be a "responsible stakeholder" in the international system. To many experts in international studies, it indicated that Washington was展开更多
文摘In this article, the relationship between the knowledge of competitors and the development of new products in the field of capital medical equipment has been investigated. In order to identify the criteria for measuring competitors’ knowledge and developing new capital medical equipment products, marketing experts were interviewed and then a researcher-made questionnaire was compiled and distributed among the statistical sample of the research. Also, in order to achieve the goals of the research, a questionnaire among 100 members of the statistical community was selected, distributed and collected. To analyze the gathered data, the structural equation modeling (SEM) method was used in the SMART PLS 2 software to estimate the model and then the K-MEAN approach was used to cluster the capital medical equipment market based on the knowledge of actual and potential competitors. The results have shown that the knowledge of potential and actual competitors has a positive and significant effect on the development of new products in the capital medical equipment market. From the point of view of the knowledge of actual competitors, the market of “MRI”, “Ultrasound” and “SPECT” is grouped in the low knowledge cluster;“Pet MRI”, “CT Scan”, “Mammography”, “Radiography, Fluoroscopy and CRM”, “Pet CT”, “SPECT CT” and “Gamma Camera” markets are clustered in the medium knowledge. Finally, “Angiography” and “CBCT” markets are located in the knowledge cluster. From the perspective of knowledge of potential competitors, the market of “angiography”, “mammography”, “SPECT” and “SPECT CT” in the low knowledge cluster, “CT scan”, “radiography, fluoroscopy and CRM”, “pet CT”, “CBCT” markets in the medium knowledge cluster and “MRI”, “pet MRI”, “ultrasound” and “gamma camera” markets in the high knowledge cluster are located.
文摘Considering China’s current economic growth, it is predictable that a surge for buying private cars will emerge around the year 2000. At that time, China will become the world’s largest automobile market. Having seen this trend, foreign automobile manufacturers are turning their eyes on China, the country with
文摘From October 18 to 19,the final of the National University Student Standardization Olympiad 2025 was successfully held at China Jiliang University in Hangzhou City,Zhejiang Province.The final attracted over 400 attendees,including members of the review expert group,representatives of organizing units,competitors,and instructors.
文摘Send us your photographs and let us know what lies behind them at contacts@chinafrica.cnHighline Challenge Competitors race on slacklines at the Yellow River Ladder Cliffs Scenic Area in Yuncheng,Shanxi Province,on 16 September.After fierce competition,Chinese athlete He Jinyi won the 100-metre sprint title.SOURCE:VCG。
基金supported by the National Natural Science Foundation of China,“Study on crown models for L arix olgensis based on tree growth” (No.31870620)。
文摘Crown development is closely related to the biomass and growth rate of the tree and its width(CW)is an important covariable in growth and yield models and in forest management.To date,various CW models have been proposed.However,limited studies have explicitly focused on additive and inherent correlation of crown components and total CW as well as the influence of competition on crown radius from the corresponding direction.In this study,two model systems were used,i.e.,aggregation method system(AMS)and disaggregation method system(DMS),to develop crown width additive model systems.For calculating spatially explicit competition index(CI),four neighbor tree selection methods were evaluated.CI was decomposed into four cardinal directions and added into the model systems.Results show that the power model form was more proper for our data to fit CW growth.For each crown radius and total CW,height to the diameter at breast height(HDR)and basal area of trees larger than the subject tree(BAL)significantly contributed to the increase of prediction accuracy.The 3-m fixed radius was optimal among the four neighborhoods selection ways.After adding decomposed competition Hegyi index into model systems AMS and DMS,the prediction accuracy improved.Of the model systems evaluated,AMS based on decomposed CI provided the best performance as well as the inherent correlation and additivity properties.Our study highlighted the importance of decomposed CI in tree CW modelling for additive model systems.This study focused on methodology and could be applied to other species or stands.
基金supported by 1RO1EY032959-01,NIH1R15GM124654-01 from NIHSchuellein Chair Endowment Fund and STEM Catalyst Grant and start-up support from the University of Dayton(to AS,MKS is Co-PI on NIH RO1 and Co-I on NIH R15)。
文摘The pathology of Alzheimer’s disease involves a long preclinical period,where the characteristic clinical symptoms of the changes in the brain are undetectable.During the preclinical period,homeostatic mechanisms may help prevent widespread cell death.Evidence has pointed towards selective cell death of diseased neurons playing a potentially protective role.As the disease progresses,dysregulation of signaling pathways that govern cell death contributes to neurodegeneration.Aberrant activation of the c-Jun N-terminal kinase pathway has been established in human and animal models of Alzheimer’s disease caused by amyloid-beta 42-or tau-mediated neurodegeneration.Clonal mosaic studies in Drosophila that examine amyloid-beta 42 in a subset of neurons suggest complex interplay between amyloid-beta 42-expressing and wild-type cells.This review examines the role of c-Jun N-terminal kinase signaling in the context of cell competition and short-range signaling interactions between amyloid-beta 42-expressing and wild-type neurons.Cell competition is a conserved phenomenon regulating tissue integrity by assessing the fitness of cells relative to their neighbors and eliminating suboptimal cells.Somatic clones of amyloid-beta 42 that juxtapose genetically distinct neuronal cell populations show promise for studying neurodegeneration.Generating genetic mosaics with labeled clones of amyloid-beta 42-or tau-expressing and wild-type neurons will allow us to understand how short-range signaling alterations trigger cell death in neurons and thereby contribute to the progression of Alzheimer’s disease.These approaches have the potential to uncover biomarkers for early Alzheimer’s disease detection and new therapeutic targets for intervention.
文摘The Union Interationale de Pentathlon Moderne(UIPM)held its first Obstacle World Championships in Beijing from October 23 to 26.The global debut attracted more than 500 competitors from 30 countries and regions.
基金the National Natural Science Foundation of China (No. 61272227)the National Key Technology Research and Development Program(No. 20121857860)the Tsinghua University Initiative Scientific Research Program (No. 20121088071)
文摘Patents are critically important for a company to protect its core business concepts and proprietary technologies. Effective patent mining in massive patent databases not only provides business enterprises with valuable insights to develop strategies for research and development, intellectual property management, and product marketing, but also helps patent offices to improve efficiency and optimize their patent examination processes. This paper describes the patent mining problem of automatically discovering core patents （i.e., novel and influential patents in a domain）. In addition, the value of core patent mining is illustrated by revealing the potential competitive relationships among companies in their core patents. The work addresses the unique patent vocabulary usage which is not considered in traditional word-based statistical methods with a topic-based temporal mining approach that quantifies a patent＇s novelty and influence through topic activeness variations. Tests of this method on real-world patent portfolios show the effectiveness of this approach over state-of-the-art methods.
文摘Change in diplomatic parlance hints at a further warming of Sino-U.S. ties, even as differences continue If there is one word that has emerged as a keyword in Sino-U.S. relations since 2005, that is "stakeholder." It first came up in a speech last September by U.S. Deputy Secretary of State Robert Zoellick, who proposed that China be a "responsible stakeholder" in the international system. To many experts in international studies, it indicated that Washington was
