The global burden of chronic non-communicable diseases(NCDs),such as cardiovascular diseases,diabetes,chronic respiratory diseases,and cancers,constitutes a paramount public health challenge of our time.While genetic ...The global burden of chronic non-communicable diseases(NCDs),such as cardiovascular diseases,diabetes,chronic respiratory diseases,and cancers,constitutes a paramount public health challenge of our time.While genetic predisposition and lifestyle factors are established contributors,a substantial portion of chronic disease etiology remains unexplained[1].Increasingly,scientific evidence points to the pervasive role of environmental factors—the air we breathe,the water we drink,and the chemicals we encounter—as critical,yet often modifiable,determinants.展开更多
We assessed the prevalence of non‐ communicable diseases（NCDs） risk factors with a focus on their clustering among healthy adults in Shenzhen, China. Data from the 2011 China Health and Nutrition Survey, comprising...We assessed the prevalence of non‐ communicable diseases（NCDs） risk factors with a focus on their clustering among healthy adults in Shenzhen, China. Data from the 2011 China Health and Nutrition Survey, comprising a regionally representative sample of 806 healthy adults aged 35 years or older, were obtained to determine the prevalence of five risk factors for NCDs. The prevalence of current smoking, central obesity, impaired fasting glucose, borderline hypertension, and borderline high total cholesterol was 19.97%, 28.29%, 4.47%, 10.55%, and 36.10%, respectively. A total 63.77% of participants had at least one risk factor. Upon examination of risk factor clustering, we observed that 7.57% of participants had at least three risk factors. Using this threshold as a cutoff, clustering of risk factors was associated with sex [odds ratio（OR） = 3.336, 95% confidence interval（CI）： 1.782 to 6.246], physical activity（OR = 1.913, 95% CI： 1.009 to 3.628）, and BMI（OR = 7.376, 95% CI： 3.812 to 14.270）. The prevalence of risk factors for NCDs is fairly high among healthy adults in Shenzhen, with a clustering tendency.展开更多
Introduction: Self evaluation is a process that defines and collects required data to judge about decision making issues at educational system on whether the educational department is fit to educate students? The obje...Introduction: Self evaluation is a process that defines and collects required data to judge about decision making issues at educational system on whether the educational department is fit to educate students? The objective of this study was determining the quality of the structural elements of the department of Communicable Diseases & determining the strengths, weaknesses, opportunities and threats to improve the quality of activities in the department under research. Materials and Methods: The employed method was Mixed methods (qualitative & quantitative research), on the basis of 10 procedural steps and within 8 sections dealing with evaluated factors;such as 1) organizational and management structure 2) scientific board members 3) students 4) Manpower 5) Space of educational research and health care 6) Equipment 7) curriculum 8) satisfaction of graduates, which were studied using 61 criteria and 172 indicators. Five-point Likert Scale was used for the responses in the questionnaire (1 - 1.75 = undesirable, to 4.2 - 5 completely desirable). Finally the data were analyzed using descriptive statistics indices and the assessment software of the Educational Development Center of TUMS. The instruments used in this method included assessment software, interview, observation and self-prepared questionnaire which consisted of 7 questionnaires and 2 check lists. Finding: The results of the research showed that general average of 8 investigating sections was 56.9% as a rather desirable research work. Conclusions: Therefore, it was concluded that function of the educational management in that group was directly in line with evaluation process, but continuing the process of evaluation seems necessary.展开更多
Introduction: Tobacco use and exposure to tobacco smoke are one of the most preventable causes of death and disability worldwide. The risk is even higher among daily tobacco consumers. The World Health Organization (W...Introduction: Tobacco use and exposure to tobacco smoke are one of the most preventable causes of death and disability worldwide. The risk is even higher among daily tobacco consumers. The World Health Organization (WHO) recommended that surveillance of major risk factors for non- communicable diseases (NCDs), such as smoking, be imperative to predicting the future burden of NCDs, identifying adequate interventions to decrease future burden and monitor trends. In 2015, a survey on NCD risk factors was conducted in Benin to estimate the prevalence of major NCD risk factors. We analyzed the data from this survey to estimate the prevalence and risk factors associated with daily tobacco consumption in Benin. Methods: A nationwide representative sample of the population was constituted in the 12 departments of Benin. The WHO STEPS wise tool was used to collect data on behavioral and demographic characteristics, including daily tobacco consumption. Tobacco consumption was subdivided into three categories: The daily consumption of tobacco, the daily consumption of smoked tobacco and non-smoked tobacco. Multivariate analysis through the weighted logistic regression was used to identify potential factors associated with daily consumption of tobacco. Results: Over the 5.126 surveyed subjects, 7.49% were daily tobacco consumers, with 3.85% being daily users of smoked tobacco and 4.36% being daily consumers of non-smoked tobacco. Men were more likely to be daily consumers of tobacco compared to women (OR = 7.42;95%CI = [4.98;11.06]). Compared to respondents aged 18 to 24, those aged 45 to 54 were five times more likely to consume tobacco (OR = 5.58;95%IC = [2.71;11.47]). Respondents residing in the departments of Atacora, Couffo and Borgou were respectively 4.28 times, 3.93 times and 2.63 times more likely to consume tobacco compared to those residing in the department of Alibori. Respondents with no education were more likely to consume tobacco daily compared to respondents who had finished high school or were in university (OR = 3.73;95%CI = [1.36;10.23]. Respondents who were overweight were less likely to be daily users of tobacco compared to people with normal weight status (OR = 0.57;95%CI = [0.34;0.96]). Conclusion: There is a relatively high prevalence of smoking in Benin, where one out of 8 people, consumes tobacco products daily. Being elderly, male, having no formal education, residing in Atacora, Borgou or Couffo were significantly associated with daily smoking. Prevention actions should thus target those sub-groups of the population.展开更多
In the present review article human diseases caused by various groups of pathogens have been explained with its etiology,epidemiology and treatment.In addition,effect of climatic changes on parasites and pathogens has...In the present review article human diseases caused by various groups of pathogens have been explained with its etiology,epidemiology and treatment.In addition,effect of climatic changes on parasites and pathogens has been demarcated with rising incidences of diseases.In response to environmental changes,mainly external and internal microenvironment of body and drug regimens taken by patients;virus is regularly changing its form and new mutant variants are coming out.These are circulating in many Indian states and cross border countries and causing high infectivity and mortality in human patients.These variants with new mutations are challenging existing drugs and other prophylactic measures and massively disrupting functions of a tissue,organ,or entire organism.Diseases caused by viruses are showing new trends in virulence,with high infectivity,morbidity and mortality.Due to climatic effect and drug resistance and new mutations in pathogens disease burden has been exacerbated enormously at global level.In all cases of helminthes,protozoan’s,fungi,bacteria,virus pathogens and parasites available drug structure seem to be failed or their usefulness has been much reduced due to evolution of new mutant variants with multiple drug resistance.There are serious failures at the level of operation,management and control of disease.The utmost failure is due to lack of appropriate vaccine,drug regimens,clinical care and awareness among people.These are major reasons that is why diseases become uncontrolled and unmanageable.展开更多
Introduction:To address the lack of long-term national–provincial comparisons,we used Global Burden of Disease(GBD)2023 data to assess the burden of non-communicable diseases(NCDs)attributable to high alcohol use acr...Introduction:To address the lack of long-term national–provincial comparisons,we used Global Burden of Disease(GBD)2023 data to assess the burden of non-communicable diseases(NCDs)attributable to high alcohol use across 31 provinciallevel administrative divisions and the Hong Kong and Macao Special Administrative Regions of China at both national and provincial levels from 1990 to 2023.Methods:We summarized deaths and disabilityadjusted life years(DALYs)for GBD Level 1 cause NCDs and alcohol-linked Level 2 causes based on the GBD comparative risk assessment framework.Analyses were stratified by cause composition,age,sex,and region.Results:In 2023,age-standardized death and DALY rates declined markedly compared with 1990,while absolute numbers rose slightly.Neoplasms contributed the largest share of DALYs,followed by substance use disorders;diabetes and kidney diseases contributed smaller shares but demonstrated substantial increases(160.22%,2010–2023).DALY peaks occurred at ages 40 to 64 years for digestive diseases,neoplasms,and substance use disorders,and at ages 65 years and older for cardiovascular diseases and diabetes and kidney diseases;neurological disorders showed the most negative values at ages 65 years and older.The male age-standardized DALY rate was 10.64 times that of females,and marked spatial heterogeneity persisted,with distinct provincial clustering by disease category.Conclusion:Despite declining age-standardized rates,the persistent absolute burden of NCDs attributable to high alcohol use and heterogeneous disease profiles support the need for cause-,age-,sex-,and region-specific prevention strategies.Public health efforts should prioritize substance use disorders,monitor the rising burden of diabetes and kidney diseases,and sustain interventions to reduce the substantial neoplasm burden.展开更多
Non-communicable diseases(NCDs)account for over 70%of all deaths worldwide each year,primarily encompassing cardiovascular diseases(CVD),cancers,diabetes,and chronic respiratory diseases[1].Unlike infectious diseases,...Non-communicable diseases(NCDs)account for over 70%of all deaths worldwide each year,primarily encompassing cardiovascular diseases(CVD),cancers,diabetes,and chronic respiratory diseases[1].Unlike infectious diseases,NCDs are closely associated with modifiable behavioral risk factors,including tobacco,high alcohol consumption,unhealthy diets,and insufficient physical activity[2,3].These behavioral risk factors are prevalent globally and exert long-term adverse effects on health,serving as primary drivers of the high prevalence and mortality rates of NCDs[4].Research indicates that over 50%of deaths related to NCDs are preventable,underscoring the significant public health value of implementing behavioral interventions aimed at preventing and controlling these diseases[5].展开更多
Cynomolgus macaques,a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius,are one of the most important nonhuman primate models for infectious disease.Although the closely ...Cynomolgus macaques,a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius,are one of the most important nonhuman primate models for infectious disease.Although the closely related rhesus macaque is classified into subspecies based on geographic origin,no such subdivision exists for cynomolgus macaques,and they continue to be used interchangeably in infectious disease research,reducing the comparability of data produced from these studies.Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas,including their genetic diversity,with macaques from insular populations such as Mauritius and the Philippines exhibiting highly restricted heterozygosity compared to mainland populations native to Indonesia or Cambodia.In the context of infectious disease studies,research into pathogens,including Ebola virus,Crimean-Congo hemorrhagic fever virus,and Mycobacterium tuberculosis have found differences in study outcomes,survival times,and immune cell responses between different populations of macaques.This review provides an overview of the differences between cynomolgus macaque populations in the context of genetic diversity,and in response to infection,and highlights the need for clear reporting of geographic origin of primates used in research.This will improve data comparison between studies and help to further refine this important animal model.展开更多
The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global he...The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global healthcare resources are intensifying challenges.In the field of nursing,in particular,the latest State of the World’s Nursing Report[1]highlights that,although the current global number of nurses is approximately 29.8 million.展开更多
Background:Disease epidemiology encompasses a wide range of health conditions,divided into communicable and noncommunicable diseases.Aim and Objective:This systematic review investigates the intricate connection betwe...Background:Disease epidemiology encompasses a wide range of health conditions,divided into communicable and noncommunicable diseases.Aim and Objective:This systematic review investigates the intricate connection between genetic susceptibility and disease development within these categories.Understanding genetic factors is crucial for improving prevention,diagnosis,and treatment strategies.The central research question is as follows:Which genes are linked to susceptibility to communicable and noncommunicable diseases,and how do these genetic elements affect susceptibility?We hypothesize that an exhaustive analysis of the literature will reveal numerous genes associated with both types of diseases,revealing the complex genetic landscape influencing susceptibility.Methodology:This systematic review follows a rigorous methodology,including comprehensive search strategies,well-defined inclusion and exclusion criteria,publication bias assessment,data extraction,quality evaluation,and data synthesis,adhering to PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)guidelines to ensure transparency and ethical presentation.Several databases,including PubMed,Embase,Springer Nature,AJOL,CrossRef,Scopus,and Web of Science,were systematically searched to retrieve published articles.Findings:In communicable diseases,the genetic factors influencing susceptibility extend beyond well-established genes,warranting further investigation under conditions such as COVID-19,HIV,tuberculosis,and hepatitis B.Noncommunicable diseases,such as cardiovascular diseases,cancer,neurological disorders,and metabolic disorders,offer promising avenues for exploring additional genetic variations.Research gaps include understanding the functional impact of the identified polymorphisms,their interaction with environmental factors,and their implications for rare diseases.Conclusion:Genome-wide association studies and gene editing therapies have the potential to expand our understanding and therapeutic options for genetically based diseases.This comprehensive review contributes to the evolving landscape of genetic susceptibility and its implications for public health and personalized medicine.展开更多
The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant e...The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant effort and expense.Monitoring is becoming more efficient thanks to technologies such as Unmanned Aerial Vehicles(UAVs),which can access hard-to-reach areas and provide real-time data.However,in disaster-affected areas,these monitoring systems may encounter many obstacles when communicating with servers or transmitting monitored data.This paper proposes an adaptive communication model to overcome the challenges faced in disaster-affected areas.A base station is responsible for collecting data(such as images and videos)captured by UAVs performing surveillance within its communication range.This station is typically a tower providing fixed cellular network service.However,in the absence of such a tower,a selected UAV may serve as the station,depending on the situation.If surveillance needs to be performed outside the coverage area,it can continue to communicate via nearby UAVs through cooperative communication.UAVs with internet support,known as the Internet of Flying Things(IoFT),will also be utilized to enhance communication capacity and efficiency.The proposed communication model is validated through experiments,showing superior data transmission performance and higher throughput.Analysis indicates it outperforms traditional systems,even in rural areas,with or without internet access.展开更多
Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of...Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.展开更多
Efficient energy utilization in covert communication sustains covertness while assuring communication quality and efficiency.This paper investigates covert communication energy efficiency(EE)in direct uplink satellite...Efficient energy utilization in covert communication sustains covertness while assuring communication quality and efficiency.This paper investigates covert communication energy efficiency(EE)in direct uplink satellite-ground communications,focusing on enhancing system EE via optimized transmit beamforming and satellite orbit altitude selection.This paper first establishes an optimization problem to maximize system EE in a direct uplink satelliteground covert communication scenario.To solve this non-convex optimization problem,it is decomposed into two subproblems and solved using the successive convex approximation(SCA)method.Based on the above methods,this paper proposes an overall iterative optimization algorithm.Simulation results demonstrate that the proposed algorithm surpasses the conventional baseline algorithms in terms of system EE.Furthermore,they elucidate the correlation between the amount of information received by the receiver and the variations in the satellite’s orbital altitude.展开更多
To address the issue of instability or even imbalance in the orientation and attitude control of quadrotor unmanned aerial vehicles(QUAVs)under random disturbances,this paper proposes a distributed antidisturbance dat...To address the issue of instability or even imbalance in the orientation and attitude control of quadrotor unmanned aerial vehicles(QUAVs)under random disturbances,this paper proposes a distributed antidisturbance data-driven event-triggered fusion control method,which achieves efficient fault diagnosis while suppressing random disturbances and mitigating communication conflicts within the QUAV swarm.First,the impact of random disturbances on the UAV swarm is analyzed,and a model for orientation and attitude control of QUAVs under stochastic perturbations is established,with the disturbance gain threshold determined.Second,a fault diagnosis system based on a high-gain observer is designed,constructing a fault gain criterion by integrating orientation and attitude information from QUAVs.Subsequently,a model-free dynamic linearization-based data modeling(MFDLDM)framework is developed using model-free adaptive control,which efficiently fits the nonlinear control model of the QUAV swarm while reducing temporal constraints on control data.On this basis,this paper constructs a distributed data-driven event-triggered controller based on the staggered communication mechanism,which consists of an equivalent QUAV controller and an event-triggered controller,and is able to reduce the communication conflicts while suppressing the influence of random interference.Finally,by incorporating random disturbances into the controller,comparative experiments and physical validations are conducted on the QUAV platforms,fully demonstrating the strong adaptability and robustness of the proposed distributed event-triggered fault-tolerant control system.展开更多
Submission.Papers appearing in the Journal comprise Editorials,Rapid Communications,Perspectives,Tutorials,Feature Articles,Reviews,Research Articles,which should contain original information,theoretical or experiment...Submission.Papers appearing in the Journal comprise Editorials,Rapid Communications,Perspectives,Tutorials,Feature Articles,Reviews,Research Articles,which should contain original information,theoretical or experimental,on any topics in the field of polymer science and polymer material science.Papers already published or scheduled to be published elsewhere should not be submitted and certainly will not be accepted.展开更多
Ningxia is an ethnic gathering area boasting abundant tourism and cultural resources.Developing the cause of tourism and culture is an important way to encourage all ethnic groups to respect differences,embrace divers...Ningxia is an ethnic gathering area boasting abundant tourism and cultural resources.Developing the cause of tourism and culture is an important way to encourage all ethnic groups to respect differences,embrace diversity,and demonstrate their interactions,exchanges,and integration in tourism activities.As an important preserve of the distinctive cultures of the Chinese nation and a prominent world tourist destination,Ningxia should strive to foster and consolidate the sense of a community with a shared future for the Chinese nation in developing its tourism and culture under the new historical conditions.It is imperative to advance the prosperity and development of tourism and culture in boosting ethnic interactions,exchanges,and integration through the formulation of tourism and cultural policies and plans,as well as the development and design of tourism and cultural projects.展开更多
文摘The global burden of chronic non-communicable diseases(NCDs),such as cardiovascular diseases,diabetes,chronic respiratory diseases,and cancers,constitutes a paramount public health challenge of our time.While genetic predisposition and lifestyle factors are established contributors,a substantial portion of chronic disease etiology remains unexplained[1].Increasingly,scientific evidence points to the pervasive role of environmental factors—the air we breathe,the water we drink,and the chemicals we encounter—as critical,yet often modifiable,determinants.
基金supported by National Project of NCDs High‐risk Population Health Management,Center for Chronic and Non‐communicable Diseases Control and Prevention,China CDC(Grant No.2013085)The Science and Technology Planning Project of Shenzhen City,Guangdong Province,China(Grant No.201602005)
文摘We assessed the prevalence of non‐ communicable diseases（NCDs） risk factors with a focus on their clustering among healthy adults in Shenzhen, China. Data from the 2011 China Health and Nutrition Survey, comprising a regionally representative sample of 806 healthy adults aged 35 years or older, were obtained to determine the prevalence of five risk factors for NCDs. The prevalence of current smoking, central obesity, impaired fasting glucose, borderline hypertension, and borderline high total cholesterol was 19.97%, 28.29%, 4.47%, 10.55%, and 36.10%, respectively. A total 63.77% of participants had at least one risk factor. Upon examination of risk factor clustering, we observed that 7.57% of participants had at least three risk factors. Using this threshold as a cutoff, clustering of risk factors was associated with sex [odds ratio（OR） = 3.336, 95% confidence interval（CI）： 1.782 to 6.246], physical activity（OR = 1.913, 95% CI： 1.009 to 3.628）, and BMI（OR = 7.376, 95% CI： 3.812 to 14.270）. The prevalence of risk factors for NCDs is fairly high among healthy adults in Shenzhen, with a clustering tendency.
文摘Introduction: Self evaluation is a process that defines and collects required data to judge about decision making issues at educational system on whether the educational department is fit to educate students? The objective of this study was determining the quality of the structural elements of the department of Communicable Diseases & determining the strengths, weaknesses, opportunities and threats to improve the quality of activities in the department under research. Materials and Methods: The employed method was Mixed methods (qualitative & quantitative research), on the basis of 10 procedural steps and within 8 sections dealing with evaluated factors;such as 1) organizational and management structure 2) scientific board members 3) students 4) Manpower 5) Space of educational research and health care 6) Equipment 7) curriculum 8) satisfaction of graduates, which were studied using 61 criteria and 172 indicators. Five-point Likert Scale was used for the responses in the questionnaire (1 - 1.75 = undesirable, to 4.2 - 5 completely desirable). Finally the data were analyzed using descriptive statistics indices and the assessment software of the Educational Development Center of TUMS. The instruments used in this method included assessment software, interview, observation and self-prepared questionnaire which consisted of 7 questionnaires and 2 check lists. Finding: The results of the research showed that general average of 8 investigating sections was 56.9% as a rather desirable research work. Conclusions: Therefore, it was concluded that function of the educational management in that group was directly in line with evaluation process, but continuing the process of evaluation seems necessary.
文摘Introduction: Tobacco use and exposure to tobacco smoke are one of the most preventable causes of death and disability worldwide. The risk is even higher among daily tobacco consumers. The World Health Organization (WHO) recommended that surveillance of major risk factors for non- communicable diseases (NCDs), such as smoking, be imperative to predicting the future burden of NCDs, identifying adequate interventions to decrease future burden and monitor trends. In 2015, a survey on NCD risk factors was conducted in Benin to estimate the prevalence of major NCD risk factors. We analyzed the data from this survey to estimate the prevalence and risk factors associated with daily tobacco consumption in Benin. Methods: A nationwide representative sample of the population was constituted in the 12 departments of Benin. The WHO STEPS wise tool was used to collect data on behavioral and demographic characteristics, including daily tobacco consumption. Tobacco consumption was subdivided into three categories: The daily consumption of tobacco, the daily consumption of smoked tobacco and non-smoked tobacco. Multivariate analysis through the weighted logistic regression was used to identify potential factors associated with daily consumption of tobacco. Results: Over the 5.126 surveyed subjects, 7.49% were daily tobacco consumers, with 3.85% being daily users of smoked tobacco and 4.36% being daily consumers of non-smoked tobacco. Men were more likely to be daily consumers of tobacco compared to women (OR = 7.42;95%CI = [4.98;11.06]). Compared to respondents aged 18 to 24, those aged 45 to 54 were five times more likely to consume tobacco (OR = 5.58;95%IC = [2.71;11.47]). Respondents residing in the departments of Atacora, Couffo and Borgou were respectively 4.28 times, 3.93 times and 2.63 times more likely to consume tobacco compared to those residing in the department of Alibori. Respondents with no education were more likely to consume tobacco daily compared to respondents who had finished high school or were in university (OR = 3.73;95%CI = [1.36;10.23]. Respondents who were overweight were less likely to be daily users of tobacco compared to people with normal weight status (OR = 0.57;95%CI = [0.34;0.96]). Conclusion: There is a relatively high prevalence of smoking in Benin, where one out of 8 people, consumes tobacco products daily. Being elderly, male, having no formal education, residing in Atacora, Borgou or Couffo were significantly associated with daily smoking. Prevention actions should thus target those sub-groups of the population.
文摘In the present review article human diseases caused by various groups of pathogens have been explained with its etiology,epidemiology and treatment.In addition,effect of climatic changes on parasites and pathogens has been demarcated with rising incidences of diseases.In response to environmental changes,mainly external and internal microenvironment of body and drug regimens taken by patients;virus is regularly changing its form and new mutant variants are coming out.These are circulating in many Indian states and cross border countries and causing high infectivity and mortality in human patients.These variants with new mutations are challenging existing drugs and other prophylactic measures and massively disrupting functions of a tissue,organ,or entire organism.Diseases caused by viruses are showing new trends in virulence,with high infectivity,morbidity and mortality.Due to climatic effect and drug resistance and new mutations in pathogens disease burden has been exacerbated enormously at global level.In all cases of helminthes,protozoan’s,fungi,bacteria,virus pathogens and parasites available drug structure seem to be failed or their usefulness has been much reduced due to evolution of new mutant variants with multiple drug resistance.There are serious failures at the level of operation,management and control of disease.The utmost failure is due to lack of appropriate vaccine,drug regimens,clinical care and awareness among people.These are major reasons that is why diseases become uncontrolled and unmanageable.
基金Supported by the Non-communicable Chronic Diseases National Science and Technology Major Project(grant numbers 2024ZD0524100 and 2024ZD0524101).
文摘Introduction:To address the lack of long-term national–provincial comparisons,we used Global Burden of Disease(GBD)2023 data to assess the burden of non-communicable diseases(NCDs)attributable to high alcohol use across 31 provinciallevel administrative divisions and the Hong Kong and Macao Special Administrative Regions of China at both national and provincial levels from 1990 to 2023.Methods:We summarized deaths and disabilityadjusted life years(DALYs)for GBD Level 1 cause NCDs and alcohol-linked Level 2 causes based on the GBD comparative risk assessment framework.Analyses were stratified by cause composition,age,sex,and region.Results:In 2023,age-standardized death and DALY rates declined markedly compared with 1990,while absolute numbers rose slightly.Neoplasms contributed the largest share of DALYs,followed by substance use disorders;diabetes and kidney diseases contributed smaller shares but demonstrated substantial increases(160.22%,2010–2023).DALY peaks occurred at ages 40 to 64 years for digestive diseases,neoplasms,and substance use disorders,and at ages 65 years and older for cardiovascular diseases and diabetes and kidney diseases;neurological disorders showed the most negative values at ages 65 years and older.The male age-standardized DALY rate was 10.64 times that of females,and marked spatial heterogeneity persisted,with distinct provincial clustering by disease category.Conclusion:Despite declining age-standardized rates,the persistent absolute burden of NCDs attributable to high alcohol use and heterogeneous disease profiles support the need for cause-,age-,sex-,and region-specific prevention strategies.Public health efforts should prioritize substance use disorders,monitor the rising burden of diabetes and kidney diseases,and sustain interventions to reduce the substantial neoplasm burden.
基金supported by the Excellent Young Science and Technology Talent Cultivation Special Project of CACMS(CI2023D006)the Xiyuan Hospital’s Support Program for Leading Talents in Traditional Chinese Medicine(0202213)the Xiyuan Hospital CACMS Enhancement Fund(XYZX0201-10).
文摘Non-communicable diseases(NCDs)account for over 70%of all deaths worldwide each year,primarily encompassing cardiovascular diseases(CVD),cancers,diabetes,and chronic respiratory diseases[1].Unlike infectious diseases,NCDs are closely associated with modifiable behavioral risk factors,including tobacco,high alcohol consumption,unhealthy diets,and insufficient physical activity[2,3].These behavioral risk factors are prevalent globally and exert long-term adverse effects on health,serving as primary drivers of the high prevalence and mortality rates of NCDs[4].Research indicates that over 50%of deaths related to NCDs are preventable,underscoring the significant public health value of implementing behavioral interventions aimed at preventing and controlling these diseases[5].
文摘Cynomolgus macaques,a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius,are one of the most important nonhuman primate models for infectious disease.Although the closely related rhesus macaque is classified into subspecies based on geographic origin,no such subdivision exists for cynomolgus macaques,and they continue to be used interchangeably in infectious disease research,reducing the comparability of data produced from these studies.Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas,including their genetic diversity,with macaques from insular populations such as Mauritius and the Philippines exhibiting highly restricted heterozygosity compared to mainland populations native to Indonesia or Cambodia.In the context of infectious disease studies,research into pathogens,including Ebola virus,Crimean-Congo hemorrhagic fever virus,and Mycobacterium tuberculosis have found differences in study outcomes,survival times,and immune cell responses between different populations of macaques.This review provides an overview of the differences between cynomolgus macaque populations in the context of genetic diversity,and in response to infection,and highlights the need for clear reporting of geographic origin of primates used in research.This will improve data comparison between studies and help to further refine this important animal model.
文摘The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global healthcare resources are intensifying challenges.In the field of nursing,in particular,the latest State of the World’s Nursing Report[1]highlights that,although the current global number of nurses is approximately 29.8 million.
文摘Background:Disease epidemiology encompasses a wide range of health conditions,divided into communicable and noncommunicable diseases.Aim and Objective:This systematic review investigates the intricate connection between genetic susceptibility and disease development within these categories.Understanding genetic factors is crucial for improving prevention,diagnosis,and treatment strategies.The central research question is as follows:Which genes are linked to susceptibility to communicable and noncommunicable diseases,and how do these genetic elements affect susceptibility?We hypothesize that an exhaustive analysis of the literature will reveal numerous genes associated with both types of diseases,revealing the complex genetic landscape influencing susceptibility.Methodology:This systematic review follows a rigorous methodology,including comprehensive search strategies,well-defined inclusion and exclusion criteria,publication bias assessment,data extraction,quality evaluation,and data synthesis,adhering to PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)guidelines to ensure transparency and ethical presentation.Several databases,including PubMed,Embase,Springer Nature,AJOL,CrossRef,Scopus,and Web of Science,were systematically searched to retrieve published articles.Findings:In communicable diseases,the genetic factors influencing susceptibility extend beyond well-established genes,warranting further investigation under conditions such as COVID-19,HIV,tuberculosis,and hepatitis B.Noncommunicable diseases,such as cardiovascular diseases,cancer,neurological disorders,and metabolic disorders,offer promising avenues for exploring additional genetic variations.Research gaps include understanding the functional impact of the identified polymorphisms,their interaction with environmental factors,and their implications for rare diseases.Conclusion:Genome-wide association studies and gene editing therapies have the potential to expand our understanding and therapeutic options for genetically based diseases.This comprehensive review contributes to the evolving landscape of genetic susceptibility and its implications for public health and personalized medicine.
文摘The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant effort and expense.Monitoring is becoming more efficient thanks to technologies such as Unmanned Aerial Vehicles(UAVs),which can access hard-to-reach areas and provide real-time data.However,in disaster-affected areas,these monitoring systems may encounter many obstacles when communicating with servers or transmitting monitored data.This paper proposes an adaptive communication model to overcome the challenges faced in disaster-affected areas.A base station is responsible for collecting data(such as images and videos)captured by UAVs performing surveillance within its communication range.This station is typically a tower providing fixed cellular network service.However,in the absence of such a tower,a selected UAV may serve as the station,depending on the situation.If surveillance needs to be performed outside the coverage area,it can continue to communicate via nearby UAVs through cooperative communication.UAVs with internet support,known as the Internet of Flying Things(IoFT),will also be utilized to enhance communication capacity and efficiency.The proposed communication model is validated through experiments,showing superior data transmission performance and higher throughput.Analysis indicates it outperforms traditional systems,even in rural areas,with or without internet access.
基金supported by the Fuxing Nursing Research Foundation of Fudan University[FNF202352].
文摘Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.
基金supported in part by the National Natural Science Foundation of China under Grants 62025110,62271093sponsored by Natural Science Foundation of Chongqing,China,under Grant CSTB2023NSCQ-LZX0108.
文摘Efficient energy utilization in covert communication sustains covertness while assuring communication quality and efficiency.This paper investigates covert communication energy efficiency(EE)in direct uplink satellite-ground communications,focusing on enhancing system EE via optimized transmit beamforming and satellite orbit altitude selection.This paper first establishes an optimization problem to maximize system EE in a direct uplink satelliteground covert communication scenario.To solve this non-convex optimization problem,it is decomposed into two subproblems and solved using the successive convex approximation(SCA)method.Based on the above methods,this paper proposes an overall iterative optimization algorithm.Simulation results demonstrate that the proposed algorithm surpasses the conventional baseline algorithms in terms of system EE.Furthermore,they elucidate the correlation between the amount of information received by the receiver and the variations in the satellite’s orbital altitude.
基金supported in part by the National Natural Science Foundation of China,Grant/Award Number:62003267the Key Research and Development Program of Shaanxi Province,Grant/Award Number:2023-GHZD-33Open Project of the State Key Laboratory of Intelligent Game,Grant/Award Number:ZBKF-23-05。
文摘To address the issue of instability or even imbalance in the orientation and attitude control of quadrotor unmanned aerial vehicles(QUAVs)under random disturbances,this paper proposes a distributed antidisturbance data-driven event-triggered fusion control method,which achieves efficient fault diagnosis while suppressing random disturbances and mitigating communication conflicts within the QUAV swarm.First,the impact of random disturbances on the UAV swarm is analyzed,and a model for orientation and attitude control of QUAVs under stochastic perturbations is established,with the disturbance gain threshold determined.Second,a fault diagnosis system based on a high-gain observer is designed,constructing a fault gain criterion by integrating orientation and attitude information from QUAVs.Subsequently,a model-free dynamic linearization-based data modeling(MFDLDM)framework is developed using model-free adaptive control,which efficiently fits the nonlinear control model of the QUAV swarm while reducing temporal constraints on control data.On this basis,this paper constructs a distributed data-driven event-triggered controller based on the staggered communication mechanism,which consists of an equivalent QUAV controller and an event-triggered controller,and is able to reduce the communication conflicts while suppressing the influence of random interference.Finally,by incorporating random disturbances into the controller,comparative experiments and physical validations are conducted on the QUAV platforms,fully demonstrating the strong adaptability and robustness of the proposed distributed event-triggered fault-tolerant control system.
文摘Submission.Papers appearing in the Journal comprise Editorials,Rapid Communications,Perspectives,Tutorials,Feature Articles,Reviews,Research Articles,which should contain original information,theoretical or experimental,on any topics in the field of polymer science and polymer material science.Papers already published or scheduled to be published elsewhere should not be submitted and certainly will not be accepted.
文摘Ningxia is an ethnic gathering area boasting abundant tourism and cultural resources.Developing the cause of tourism and culture is an important way to encourage all ethnic groups to respect differences,embrace diversity,and demonstrate their interactions,exchanges,and integration in tourism activities.As an important preserve of the distinctive cultures of the Chinese nation and a prominent world tourist destination,Ningxia should strive to foster and consolidate the sense of a community with a shared future for the Chinese nation in developing its tourism and culture under the new historical conditions.It is imperative to advance the prosperity and development of tourism and culture in boosting ethnic interactions,exchanges,and integration through the formulation of tourism and cultural policies and plans,as well as the development and design of tourism and cultural projects.
