Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges...Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).展开更多
BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Resear...BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Research in developing nations relating to the cost of treatment is scarce when compared with developed countries.Thus,the drug utilization research studies from developing nations are most needed,and their number has been growing.AIM To evaluate patterns of utilization of antipsychotic drugs and direct medical cost analysis in patients newly diagnosed with schizophrenia.METHODS The present study was observational in type and based on a retrospective cohort to evaluate patterns of utilization of antipsychotic drugs using World Health Organization(WHO)core prescribing indicators and anatomical therapeutic chemical/defined daily dose indicators.We also calculated direct medical costs for a period of 6 months.RESULTS This study has found that atypical antipsychotics are the mainstay of treatment for schizophrenia in every age group and subcategories of schizophrenia.The evaluation based on WHO prescribing indicators showed a low average number of drugs per prescription and low prescribing frequency of antipsychotics from the National List of Essential Medicines 2015 and the WHO Essential Medicines List 2019.The total mean drug cost of our study was 1396 Indian rupees.The total mean cost due to the investigation in our study was 1017.34 Indian rupees.Therefore,the total mean direct medical cost incurred on patients in our study was 4337.28 Indian rupees.CONCLUSION The information from the present study can be used for reviewing and updating treatment policy at the institutional level.展开更多
Co-occurrence pattern of fish species plays an important role in understanding the spatio-temporal structure and the stability of fish community.Species coexistence may vary with time and space.The co-occurrence patte...Co-occurrence pattern of fish species plays an important role in understanding the spatio-temporal structure and the stability of fish community.Species coexistence may vary with time and space.The co-occurrence patterns of fish species were examined using the C-score under fixed-fixed null model for fish communities in spring and autumn over different years in the Haizhou Bay,China.The results showed that fish assemblages in the whole bay had non-random patterns in spring and autumn over different years.However,the fish co-occurrence patterns were different for the northern and southern fish assemblages in spring and autumn.The northern fish assemblage showed structured pattern,whereas the southern assemblage were randomly assembled in spring.The co-occurrence patterns of fish communities were relatively stable over different years,and the number of significant species pairs in northern assemblage was more than that in the southern assemblage.Environmental heterogeneity played an important role in determining the distributions of fish species that formed significant species pairs,which might affect the co-occurrence patterns of northern and southern assemblages further in the Haizhou Bay.展开更多
One of the fundamental questions in community ecology is whether communities are random or formed by deterministic mechanisms. Although many efforts have been made to verify non-randomness in community structure, litt...One of the fundamental questions in community ecology is whether communities are random or formed by deterministic mechanisms. Although many efforts have been made to verify non-randomness in community structure, little is known with regard to co-occurrence patterns in above-ground and below-ground communities. In this paper, we used a null model to test non-randomness in the structure of the above-ground and below-ground mite communities in farmland of the Sanjiang Plain, Northeast China. Then, we used four tests for non-randomness to recognize species pairs that would be demonstrated as significantly aggregated or segregated co-occurrences of the above-ground and below-ground mite communities. The pattern of the above-ground mite commu- nity was significantly non-random in October, suggesting species segregation and hence interspecific competition. Additionally, species co-occurrence patterns did not differ from randomness in the above-ground mite community in August or in below-ground mite com- munities in August and October. Only one significant species pair was detected in the above-ground mite community in August, while no significant species pairs were recognized in the above-ground mite community in October or in the below-ground mite communities in August and October. The results indicate that non-randomness and significant species pairs may not be the general rule in the above-ground and below-ground mite communities in farmland of the Sanjiang Plain at the fine scale.展开更多
Nitrogen(N)deep placement has been found to reduce N leaching and increase N use efficiency in paddy fields.However,relatively little is known how bacterial consortia,especially abundant and rare taxa,respond to N dee...Nitrogen(N)deep placement has been found to reduce N leaching and increase N use efficiency in paddy fields.However,relatively little is known how bacterial consortia,especially abundant and rare taxa,respond to N deep placement,which is critical for understanding the biodiversity and function of agricultural ecosystem.In this study,lllumina sequencing and ecological models were conducted to examine the diversity patterns and underlying assembly mechanisms of abundant and rare taxa in rice rhizosphere soil under different N fertilization regimes at four rice growth stages in paddy fields.The results showed that abundant and rare bacteria had distinct distribution patterns in rhizosphere samples.Abundant bacteria showed ubiquitous distribution;while rare taxa exhibited uneven distribution across all samples.Stochastic processes dominated community assembly of both abundant and rare bacteria,with dispersal limitation playing a more vital role in abundant bacteria,and undominated processes playing a more important role in rare bacteria.The N deep placement was associated with a greater influence of dispersal limitation than the broadcast N fertilizer(BN)and no N fertilizer(NN)treatments in abundant and rare taxa of rhizosphere soil;while greater contributions from homogenizing dispersal were observed for BN and NN in rare taxa.Network analysis indicated that abundant taxa with closer relationships were usually more likely to occupy the central position of the network than rare taxa.Nevertheless,most of the keystone species were rare taxa and might have played essential roles in maintaining the network stability.Overall,these findings highlighted that the ecological mechanisms and co-occurrence patterns of abundant and rare bacteria in rhizosphere soil under N deep placement.展开更多
The Upper Guinea Forest is subject to heavy deforestation. In this context, many endemic and/or rare plant species are threatened with extinction. This is the case of Aubregrinia taïensis (Aubrév. & Pell...The Upper Guinea Forest is subject to heavy deforestation. In this context, many endemic and/or rare plant species are threatened with extinction. This is the case of Aubregrinia taïensis (Aubrév. & Pellegr.) Heine, a critically endangered Sapotaceae species, endemic to Côte d’Ivoire and Ghana. After 3 years of investigation in and around the Tai National Park (TNP) in the West of Côte d’Ivoire, only one individual of this species was located and no sexual reproductive organs (fruits, seeds) were observed. Woody plant species around this individual were inventoried in order to know the species that can co-occur with Aubregrinia taïensis. For that a plot of 30 m of diameter was established around the individual and all of the woody species of this circle were inventoried. Then, the taxonomic diversity, the chorology of the species, the conservation status and their life-form were recorded. A total of 130 woody plant species belonging to 51 families were collected in the site. The most represented families are Euphorbiaceae (12 spp.), Rubiaceae (10 spp.), Annonaceae (7 spp.), Fabaceae, Moraceae, Malvaceae (6 spp. each) while the most represented genera are Diospyros L. (4 spp.), Cola Schott & Endl. and Vitex L. (3 spp.). Species from the Guineo-Congolese Region (GC) are the most abundant (72%). They are followed by West African endemic species (GCW, 19%). Microphanerophytes (mp) are the most abundant and represent more than 40% of the species. Three vulnerable species were found in this plot: Campylospermum amplectens, Placodiscus boya and Trichoscypha cavalliensis. Thus, the preservation of this forest is more than necessary.展开更多
Background: Participating in working life is important for most peoples’ economy, self-confidence, independence, social life, and feeling of belonging. Persons with co-occurring severe mental health difficulties and ...Background: Participating in working life is important for most peoples’ economy, self-confidence, independence, social life, and feeling of belonging. Persons with co-occurring severe mental health difficulties and substance use problems have challenges in entering working life. Objective: The aim of the study was to explore the importance of work and activity for the recovery of persons with co-occurring severe mental health difficulties and substance use problems and to determine the significant elements that aid them in getting into work and/or meaningful activities. Methods: A professional development program was conducted to explore how following-up on these persons could lead to participation in working life. The data were collected through qualitative interviews with 24 participants, and with 25 of those carrying out the follow-up. Results: The participants described the benefit from the follow-up as well. They expressed enthusiasm for work and vocational training, although they all did not obtain work. Many had a better life, with more daily structure and less substance abuse. The personal encounter between the helper and the participant was ascribed crucial importance— being respected and valued, being relied on, and being able to be honest were considered significant. Conclusions: The participants valued work and regular activities, a more structured life, decreased drug abuse, and altogether a better life. The helpers’ respect, recognition and their ability to see dignity through wretchedness?and broken agreements were important. The participants emphasized the importance of getting help for different problems from different helpers at the same time, and the providers’ interdisciplinary collaboration in teams was essential. It seems that the supported employment philosophy on speedy job seeking ought to be adapted to this target group and that prior social training may be necessary.展开更多
The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and...The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and mixed reality applications.Alongside the controlled synthesis of high-performance QDs,a reliable QD patterning technology is crucial in overcoming this challenge.Among the various methods available,photolithography-based patterning technologies show great potentials in producing ultra-fine QD patterns at micron scale.This review article presents the recent advancements in the field of QD patterning using photolithography techniques and explores their applications in micro-display technology.Firstly,we discuss QD patterning through photolithography techniques employing photoresist(PR),which falls into two categories:PRassisted photolithography and photolithography of QDPR.Subsequently,direct photolithography techniques based on photo-induced crosslinking of photosensitive groups and photo-induced ligand cleavage mechanisms are thoroughly reviewed.Meanwhile,we assess the performance of QD arrays fabricated using these photolithography techniques and their integration into QD light emitting diode display devices as well as color conversionbased micro light emitting diode display devices.Lastly,we summarize the most recent developments in this field and outline future prospects.展开更多
The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geog...The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.展开更多
Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guang...Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guangdong and Guangxi sections of the Pearl River Basin as examples,the transfer-matrix method and standard deviation ellipse model were applied to characterize the evolution of territorial space patterns from 1990 to 2020.A trend surface analysis and the Theil index were used to analyze regional differences in the evolution process,and geodetectors were used to identify the underlying mechanisms of the changes.There were three key results.(1)In these critical areas of the Pearl River Basin,agricultural and ecological spaces have rapidly declined due to urban expansion,with transfers between these spaces dominating the evolution of territorial space patterns.Spatial pattern changes in the Guangdong section were more intense than in the Guangxi section.(2)Regional differences in urban space have decreased,whereas differences in agricultural and ecological spaces have intensified.Driven by socio-economic growth,the cross-regional transfers of territorial space have created a“high in the east,while low in the west”inter-regional difference,and a“high in the south,while low in the north”intra-regional difference shaped by natural conditions.The regional differences in space patterns were greater in Guangdong than in Guangxi.(3)The evolution of watershed territorial space patterns resulted from scale changes,locational shifts,structural reorganizations,and directional changes driven by multiple factors.Natural environment,social life,economic development,and policy factors played foundational,leading,key driving,and guiding roles,respectively.Additionally,the regional differences in the evolution of watershed territorial space patterns originated from the differential transmission of the influence of various factors affecting spatial evolution.Enhancing urban space efficiency,restructuring agricultural space,and optimizing ecological space are key strategies for building a complementary and synergistic territorial space pattern in the basin.展开更多
Objective weather classification methods have been extensively applied to identify dominant ozone-favorable synoptic weather patterns(SWPs),however,the consistency of different classification methods is rarely examine...Objective weather classification methods have been extensively applied to identify dominant ozone-favorable synoptic weather patterns(SWPs),however,the consistency of different classification methods is rarely examined.In this study,we apply two widely-used objective methods,the self-organizing map(SOM)and K-means clustering analysis,to derive ozone-favorable SWPs at four Chinese megacities in 2015-2022.We find that the two algorithms are largely consistent in recognizing dominant ozone-favorable SWPs for four Chinese megacities.In the case of classifying six SWPs,the derived circulation fields are highly similar with a spatial correlation of 0.99 between the two methods,and the difference in themean frequency of each SWP is less than 7%.The six dominant ozone-favorable SWPs in Guangzhou are all characterized by anomaly higher radiation and temperature,lower cloud cover,relative humidity,and wind speed,and stronger subsidence compared to climatology mean.We find that during 2015-2022,the occurrence of ozone-favorable SWPs days increases significantly at a rate of 3.2 days/year,faster than the increases in the ozone exceedance days(3.0 days/year).The interannual variability between the occurrence of ozone-favorable SWPs and ozone exceedance days are generally consistent with a temporal correlation coefficient of 0.6.In particular,the significant increase in ozone-favorable SWPs in 2022,especially the Subtropical High type which typically occurs in September,is consistent with a long-lasting ozone pollution episode in Guangzhou during September 2022.Our results thus reveal that enhanced frequency of ozone-favorable SWPs plays an important role in the observed 2015-2022 ozone increase in Guangzhou.展开更多
Rock fractures or faults could be reactivated by the thermal stress generated during the decay process of the high-level radioactive waste in deep geological repositories(DGRs).Understanding thermoshearing behavior an...Rock fractures or faults could be reactivated by the thermal stress generated during the decay process of the high-level radioactive waste in deep geological repositories(DGRs).Understanding thermoshearing behavior and its influencing factors are important for the long-term performance assessment of DGRs.We designed multistage mechanical(M)shear tests and thermomechanical(TM)shear tests on three 100 mm-cubic granite specimens,each containing a single inclined sawcut fracture with distinct microroughness of 8-15μm.M test results have shown that the static friction coefficient of the granite fracture decreases in proportion to the increase in the logarithm of the loading rate within the range of 1-15 kPa/s.For the given heating and boundary conditions,thermal loading rate,i.e.,thermal stress increment with heating time,is measured to be around 1 kPa/s in the fractured granite.Thermoshearing can be well predicted by the linear Mohr-Coulomb failure envelope deduced from M shear tests employing a loading rate that is comparable with the thermal loading rate.The granite fractures exhibited two distinct slip patterns during the mechanical shearing,i.e.,stick-slip observed in the smooth fracture and stable sliding in the relatively rough surface.In contrast,the mechanical loading rate(1-15 kPa/s)investigated in this study appears to not influence the slip pattern.Unlike those in M shear tests,thermoshearing in both smooth and relatively rough fractures show stable sliding with a very slow peak velocity of around 0.002μm/s.展开更多
In the era of the digital economy,digital trade has demonstrated strong vitality,becoming a crucial driving force for the highquality development of national and regional economies.However,understanding the resilience...In the era of the digital economy,digital trade has demonstrated strong vitality,becoming a crucial driving force for the highquality development of national and regional economies.However,understanding the resilience of digital trade in the face of external crises is an important topic.Taking the backdrop of Sino-US trade friction,this paper constructs a resilience index system for digital trade.It utilizes entropy method,kernel density estimation,and ArcGIS mapping to calculate and visually analyze the resilience of China’s digital trade from 2017 to 2021.Additionally,a Tobit model is constructed to explore the main influencing factors of digital trade resilience patterns.The research findings indicate:1)temporally,during the period of Sino-US trade friction,China’s digital trade resilience shows an overall upward trend,but there are regional differences in resilience levels across the country,with a severe polarization phenomenon.2)Spatially,high resilience is observed in the eastern and central regions of China,while the western and northeastern regions exhibit low resilience.3)From a dimensional perspective,the resistance of digital trade resilience displays a spatial distribution of high values in the east and low values in the west.The recovery force is aggregated along coastal areas,and the renewal force tends to aggregate along the eastern coastline.4)Factors such as economic scale,industrial structure,urbanization rate,government fiscal expenditure,and technological talents significantly promote the enhancement of digital trade resilience.This study reveals the dynamic characteristics and influencing factors of digital trade resilience in responding to external shocks,providing theoretical basis and policy suggestions for enhancing digital trade resilience,and promoting high-quality economic development in China.展开更多
A custom micro-arc oxidation(MAO)apparatus is employed to produce coatings under optimized constant voltage–current two-step power supply mode.Various analytical techniques,including scanning electron microscopy,conf...A custom micro-arc oxidation(MAO)apparatus is employed to produce coatings under optimized constant voltage–current two-step power supply mode.Various analytical techniques,including scanning electron microscopy,confocal laser microscopy,X-ray diffraction,X-ray photoelectron spectroscopy,transmission electron microscopy,and electrochemical analysis,are employed to characterize MAO coatings at different stages of preparation.MAO has MgO,hydroxyapatite,Ca_(3)(PO_(4))_(2),and Mg2SiO4 phases.Its microstructure of the coating is characterized by"multiple breakdowns,pores within pores",and"repaired blind pores".The porosity and the uniformity of MAO coating first declines in the constant voltage mode,then augments while the discharge phenomenon takes place,and finally decreases in the repair stage.These analyses reveal a four-stage growth pattern for MAO coatings:anodic oxidation stage,micro-arc oxidation stage,breakdown stage,and repairing stage.During anodic oxidation and MAO stages,inward growth prevails,while the breakdown stage sees outward and accelerated growth.Simultaneous inward and outward growth in the repair stage results in a denser,more uniform coating with increased thickness and improved corrosion resistance.展开更多
The isolated fracture-vug systems controlled by small-scale strike-slip faults within ultra-deep carbonate rocks of the Tarim Basin exhibit significant exploration potential.The study employs a novel training set inco...The isolated fracture-vug systems controlled by small-scale strike-slip faults within ultra-deep carbonate rocks of the Tarim Basin exhibit significant exploration potential.The study employs a novel training set incorporating innovative fault labels to train a U-Net-structured CNN model,enabling effective identification of small-scale strike-slip faults through seismic data interpretation.Based on the CNN faults,we analyze the distribution patterns of small-scale strike-slip faults.The small-scale strike-slip faults can be categorized into NNW-trending and NE-trending groups with strike lengths ranging 200–5000 m.The development intensity of small-scale strike-slip faults in the Lower Yingshan Member notably exceeds that in the Upper Member.The Lower and Upper Yingshan members are two distinct mechanical layers with contrasting brittleness characteristics,separated by a low-brittleness layer.The superior brittleness of the Lower Yingshan Member enhances the development intensity of small-scale strike-slip faults compared to the upper member,while the low-brittleness layer exerts restrictive effects on vertical fault propagation.Fracture-vug systems formed by interactions of two or more small-scale strike-slip faults demonstrate larger sizes than those controlled by individual faults.All fracture-vug system sizes show positive correlations with the vertical extents of associated small-scale strike-slip faults,particularly intersection and approaching fracture-vug systems exhibit accelerated size increases proportional to the vertical extents.展开更多
The transport of suspended particulate matter is a crucial aspect of studies on sediment source-to-sink processes.However,research on its transport patterns in high-erosion areas of low-latitude seas remains limited.T...The transport of suspended particulate matter is a crucial aspect of studies on sediment source-to-sink processes.However,research on its transport patterns in high-erosion areas of low-latitude seas remains limited.To elucidate modern land-sea interaction processes controlled by the monsoon climate,this study investigates the seasonal transport patterns and control mechanisms of suspended particulate matter in the western Sunda Shelf.Results reveal significant seasonal variations in the spatial distribution of suspended particulate matter concentrations,with elevated levels observed during autumn compared with spring.These differences are directly attributed to the East Asian monsoon,including seasonal monsoon precipitation and the associated transport dynamics.During the northeast monsoon,the Malay Peninsula serves as a primary source for the western sea area,with terrestrial materials from its rivers transported to the northern Gulf of Thailand.This transport pattern shifts to an S-shaped,clockwise circulation during upwelling events.Conversely,in the southwest monsoon,rivers in the northern Gulf of Thailand become the predominant sources for the Sunda Shelf,with terrestrial materials carried by clockwise currents toward the eastern Malay Peninsula.When upwelling occurs off the southern Indochina Peninsula,one branch heads toward the South China Sea and the other toward the southern tip of the Malay Peninsula.The seasonal variation in material sources is further supported by the distribution of clay minerals and the discrimination results of rare earth element proxies,including(La/Sm)UCC-(Gd/Yb)UCCand(La/Yb)UCC-(Gd/Yb)UCC,in surface sediments from the Sunda Shelf and surrounding marine areas.展开更多
Gastric cancer(GC)represents a significant global health burden due to its high morbidity and mortality.Specific behaviors of GC sub-types,distinct dissem-ination patterns,and associated risk-factors remain poorly und...Gastric cancer(GC)represents a significant global health burden due to its high morbidity and mortality.Specific behaviors of GC sub-types,distinct dissem-ination patterns,and associated risk-factors remain poorly understood.This editorial highlights several key prognostic factors,including pathological staging and vascular invasion,that impact GC.It examines a recent study’s investigation of differential metastatic lymph nodes distribution and survival in upper and lower GC sub-types,focusing on histological characterization,pathophysiology,usage of neoadjuvant chemotherapy,and additional predictive determinants.We assess the statistical robustness and clinical applicability of the findings,un-derscoring the importance of treating GC as a heterogeneous disease and em-phasizing how tailored surgical approaches informed by lymph node distribution can optimize tumor detection while minimizing unnecessary interventions.The study’s large cohort,multi-center design,and strict inclusion criteria strengthen its validity in guiding surgical planning and risk-stratification.However,inte-grating genetic and molecular data is critical for refining models and broadening applicability.Additionally,recurrence-metrics and infection-related factors,such as Helicobacter pylori and Epstein-Barr virus,absent in the original study,remain vital for directing future research.By bridging metastatic patterns with pros-pective methodologies and inclusion of diverse populations,this editorial pro-vides a framework for advancing early detection and personalized GC care.展开更多
BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have ...BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no research.AIM To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic intervention.METHODS A cross-sectional survey was disseminated among ophthalmologists all over India.The survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up patterns.RESULTS A total of 180 ophthalmologists responded to the survey.Most practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was advised.The most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid surgeries.Sixty-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease patients.CONCLUSION Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular conditions.Many ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract surgery.Eyelid conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.展开更多
Chaoshan drawnwork handkerchief design exhibits self-similarity and fractal characteristics due to their grid-based structure,overall symmetry,and the way local motifs reflect the whole pattern.To explore the potentia...Chaoshan drawnwork handkerchief design exhibits self-similarity and fractal characteristics due to their grid-based structure,overall symmetry,and the way local motifs reflect the whole pattern.To explore the potential of fractals in traditional textile design,a fractal-based generative framework was proposed for efficiently creating drawnwork patterns suitable for practical handicraft production.The research was initiated with an analysis of the structural composition of center,skeleton,and filler motifs extracted from a pattern sample library.Based on this hierarchical classification,the box-counting method was employed to calculate their respective fractal dimensions.Building on fractal art theory,generative algorithms,and studies on the application of Ultra Fractal,a Chaoshan drawnwork fractal design model was established.Using this model,51 drawnwork fractal patterns and 153 handkerchief patterns were generated.These patterns were subsequently applied in real-world production to validate the feasibility and value of fractal techniques in textile design.展开更多
基金the Chinese Academy of Sciences Research Center for Ecology and Environment of Central Asia(RCEECA),the construction and joint research for the China-Tajikistan“Belt and Road”Joint Laboratory on Biodiversity Conservation and Sustainable Use(2024YFE0214200)the Shanghai Cooperation Organization Partnership and International Technology Cooperation Plan of Science and Technology Projects(2023E01018,2025E01056)the Chinese Academy of Sciences President’s International Fellowship Initiative(PIFI)(2024VBC0006).
文摘Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).
文摘BACKGROUND Drug utilization research has an important role in assisting the healthcare administration to know,compute,and refine the prescription whose principal objective is to enable the rational use of drugs.Research in developing nations relating to the cost of treatment is scarce when compared with developed countries.Thus,the drug utilization research studies from developing nations are most needed,and their number has been growing.AIM To evaluate patterns of utilization of antipsychotic drugs and direct medical cost analysis in patients newly diagnosed with schizophrenia.METHODS The present study was observational in type and based on a retrospective cohort to evaluate patterns of utilization of antipsychotic drugs using World Health Organization(WHO)core prescribing indicators and anatomical therapeutic chemical/defined daily dose indicators.We also calculated direct medical costs for a period of 6 months.RESULTS This study has found that atypical antipsychotics are the mainstay of treatment for schizophrenia in every age group and subcategories of schizophrenia.The evaluation based on WHO prescribing indicators showed a low average number of drugs per prescription and low prescribing frequency of antipsychotics from the National List of Essential Medicines 2015 and the WHO Essential Medicines List 2019.The total mean drug cost of our study was 1396 Indian rupees.The total mean cost due to the investigation in our study was 1017.34 Indian rupees.Therefore,the total mean direct medical cost incurred on patients in our study was 4337.28 Indian rupees.CONCLUSION The information from the present study can be used for reviewing and updating treatment policy at the institutional level.
基金funded by the National Natural Science Foundation of China (No. 31772852)the Fundamental Research Funds for the Central Universities (Nos. 2015 62030, 201612004)the Public Science and Technology Research Funds Projects of Ocean (No. 201305030)
文摘Co-occurrence pattern of fish species plays an important role in understanding the spatio-temporal structure and the stability of fish community.Species coexistence may vary with time and space.The co-occurrence patterns of fish species were examined using the C-score under fixed-fixed null model for fish communities in spring and autumn over different years in the Haizhou Bay,China.The results showed that fish assemblages in the whole bay had non-random patterns in spring and autumn over different years.However,the fish co-occurrence patterns were different for the northern and southern fish assemblages in spring and autumn.The northern fish assemblage showed structured pattern,whereas the southern assemblage were randomly assembled in spring.The co-occurrence patterns of fish communities were relatively stable over different years,and the number of significant species pairs in northern assemblage was more than that in the southern assemblage.Environmental heterogeneity played an important role in determining the distributions of fish species that formed significant species pairs,which might affect the co-occurrence patterns of northern and southern assemblages further in the Haizhou Bay.
基金Under the auspices of National Natural Science Foundation of China(No.41101049,40601047,41371072,31101617,41171047)China Postdoctoral Science Foundation(No.2012M511361)+2 种基金Excellent Youth Scholars of Northeast Institute of Geography and Agroecology,Chinese Academy of Sciences(No.DLSYQ2012004)Fund for Distinguished Young Scholar of Harbin Normal University(No.KGB201204)Scientific Innovation Project for Doctoral Candidate of Harbin Normal University(No.HSDBSCX2012-07)
文摘One of the fundamental questions in community ecology is whether communities are random or formed by deterministic mechanisms. Although many efforts have been made to verify non-randomness in community structure, little is known with regard to co-occurrence patterns in above-ground and below-ground communities. In this paper, we used a null model to test non-randomness in the structure of the above-ground and below-ground mite communities in farmland of the Sanjiang Plain, Northeast China. Then, we used four tests for non-randomness to recognize species pairs that would be demonstrated as significantly aggregated or segregated co-occurrences of the above-ground and below-ground mite communities. The pattern of the above-ground mite commu- nity was significantly non-random in October, suggesting species segregation and hence interspecific competition. Additionally, species co-occurrence patterns did not differ from randomness in the above-ground mite community in August or in below-ground mite com- munities in August and October. Only one significant species pair was detected in the above-ground mite community in August, while no significant species pairs were recognized in the above-ground mite community in October or in the below-ground mite communities in August and October. The results indicate that non-randomness and significant species pairs may not be the general rule in the above-ground and below-ground mite communities in farmland of the Sanjiang Plain at the fine scale.
基金the National Key Research and Development Program of China(2016YFD0200309 and 2018YFD0301104-01).
文摘Nitrogen(N)deep placement has been found to reduce N leaching and increase N use efficiency in paddy fields.However,relatively little is known how bacterial consortia,especially abundant and rare taxa,respond to N deep placement,which is critical for understanding the biodiversity and function of agricultural ecosystem.In this study,lllumina sequencing and ecological models were conducted to examine the diversity patterns and underlying assembly mechanisms of abundant and rare taxa in rice rhizosphere soil under different N fertilization regimes at four rice growth stages in paddy fields.The results showed that abundant and rare bacteria had distinct distribution patterns in rhizosphere samples.Abundant bacteria showed ubiquitous distribution;while rare taxa exhibited uneven distribution across all samples.Stochastic processes dominated community assembly of both abundant and rare bacteria,with dispersal limitation playing a more vital role in abundant bacteria,and undominated processes playing a more important role in rare bacteria.The N deep placement was associated with a greater influence of dispersal limitation than the broadcast N fertilizer(BN)and no N fertilizer(NN)treatments in abundant and rare taxa of rhizosphere soil;while greater contributions from homogenizing dispersal were observed for BN and NN in rare taxa.Network analysis indicated that abundant taxa with closer relationships were usually more likely to occupy the central position of the network than rare taxa.Nevertheless,most of the keystone species were rare taxa and might have played essential roles in maintaining the network stability.Overall,these findings highlighted that the ecological mechanisms and co-occurrence patterns of abundant and rare bacteria in rhizosphere soil under N deep placement.
文摘The Upper Guinea Forest is subject to heavy deforestation. In this context, many endemic and/or rare plant species are threatened with extinction. This is the case of Aubregrinia taïensis (Aubrév. & Pellegr.) Heine, a critically endangered Sapotaceae species, endemic to Côte d’Ivoire and Ghana. After 3 years of investigation in and around the Tai National Park (TNP) in the West of Côte d’Ivoire, only one individual of this species was located and no sexual reproductive organs (fruits, seeds) were observed. Woody plant species around this individual were inventoried in order to know the species that can co-occur with Aubregrinia taïensis. For that a plot of 30 m of diameter was established around the individual and all of the woody species of this circle were inventoried. Then, the taxonomic diversity, the chorology of the species, the conservation status and their life-form were recorded. A total of 130 woody plant species belonging to 51 families were collected in the site. The most represented families are Euphorbiaceae (12 spp.), Rubiaceae (10 spp.), Annonaceae (7 spp.), Fabaceae, Moraceae, Malvaceae (6 spp. each) while the most represented genera are Diospyros L. (4 spp.), Cola Schott & Endl. and Vitex L. (3 spp.). Species from the Guineo-Congolese Region (GC) are the most abundant (72%). They are followed by West African endemic species (GCW, 19%). Microphanerophytes (mp) are the most abundant and represent more than 40% of the species. Three vulnerable species were found in this plot: Campylospermum amplectens, Placodiscus boya and Trichoscypha cavalliensis. Thus, the preservation of this forest is more than necessary.
文摘Background: Participating in working life is important for most peoples’ economy, self-confidence, independence, social life, and feeling of belonging. Persons with co-occurring severe mental health difficulties and substance use problems have challenges in entering working life. Objective: The aim of the study was to explore the importance of work and activity for the recovery of persons with co-occurring severe mental health difficulties and substance use problems and to determine the significant elements that aid them in getting into work and/or meaningful activities. Methods: A professional development program was conducted to explore how following-up on these persons could lead to participation in working life. The data were collected through qualitative interviews with 24 participants, and with 25 of those carrying out the follow-up. Results: The participants described the benefit from the follow-up as well. They expressed enthusiasm for work and vocational training, although they all did not obtain work. Many had a better life, with more daily structure and less substance abuse. The personal encounter between the helper and the participant was ascribed crucial importance— being respected and valued, being relied on, and being able to be honest were considered significant. Conclusions: The participants valued work and regular activities, a more structured life, decreased drug abuse, and altogether a better life. The helpers’ respect, recognition and their ability to see dignity through wretchedness?and broken agreements were important. The participants emphasized the importance of getting help for different problems from different helpers at the same time, and the providers’ interdisciplinary collaboration in teams was essential. It seems that the supported employment philosophy on speedy job seeking ought to be adapted to this target group and that prior social training may be necessary.
基金supported by the National Natural Science Foundation of China(62374142,12175189 and 11904302)External Cooperation Program of Fujian(2022I0004)+1 种基金Fundamental Research Funds for the Central Universities(20720190005 and 20720220085)Major Science and Technology Project of Xiamen in China(3502Z20191015).
文摘The preparation of red,green,and blue quantum dot(QD)pixelated arrays with high precision,resolution,and brightness poses a significant challenge on the development of advanced micro-displays for virtual,augmented,and mixed reality applications.Alongside the controlled synthesis of high-performance QDs,a reliable QD patterning technology is crucial in overcoming this challenge.Among the various methods available,photolithography-based patterning technologies show great potentials in producing ultra-fine QD patterns at micron scale.This review article presents the recent advancements in the field of QD patterning using photolithography techniques and explores their applications in micro-display technology.Firstly,we discuss QD patterning through photolithography techniques employing photoresist(PR),which falls into two categories:PRassisted photolithography and photolithography of QDPR.Subsequently,direct photolithography techniques based on photo-induced crosslinking of photosensitive groups and photo-induced ligand cleavage mechanisms are thoroughly reviewed.Meanwhile,we assess the performance of QD arrays fabricated using these photolithography techniques and their integration into QD light emitting diode display devices as well as color conversionbased micro light emitting diode display devices.Lastly,we summarize the most recent developments in this field and outline future prospects.
基金funded by the Yunnan Provincial Basic Research Joint Special Fund Project(2019FH001(-052))Cangshan Mountain Synthetic Scientific Expeditions Fund.
文摘The Hengduan Mountains,situated on the southeastern edge of the Qinghai-Tibet Plateau,are the longest and widest north-south-oriented mountain range in China,exerting a significant influence on the ecological and geographical pattern.Understanding the topographic and geomorphological characteristics of the Hengduan Mountains is fundamental and crucial for research in related fields such as ecology,geography,and sustainability.In this study,Digital Elevation Model(DEM)data were utilized to extract and analyze the topography and geomorphology(TG)pattern.TG maps have been developed to quantitatively classify the TG types in the Hengduan Mountains by combining the five factors of elevation,slope,aspect,relief and landform.The spatial distribution and quantitative characteristics of these factors were mapped and investigated using geographic information systems.The results revealed that:(1)The Hengduan Mountains exhibit an elongated north-south distribution,with an average elevation of approximately 3746 m,an average slope of around 25°,and an average relief of about 266 m.(2)The Hengduan Mountains display significant elevation differences,with an overall high elevation,characterized by a trend of lower elevation in the east and higher elevation in the west,as well as irregular orientations of various aspects.(3)The 19 landform types were identified,the landform types of the Hengduan Mountains are primarily composed of low-relief high-mountains(42.0618%),low-relief mid-mountains(22.4624%),and high-elevation hills(20.5839%).The results of the study can provide data and information support for the ecology,environmental protection and sustainable development of the Hengduan Mountains.
基金National Social Science Foundation Program,No.22VRC163National Natural Science Foundation of China,No.42061043+1 种基金Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.KYCX24_1008Innovation Project of Guangxi Graduate Education,No.YCSW2024473。
文摘Clarifying the mechanisms that control the evolution of territorial space patterns is essential for regulating and optimizing the geographical structure and processes related to sustainable development.Using the Guangdong and Guangxi sections of the Pearl River Basin as examples,the transfer-matrix method and standard deviation ellipse model were applied to characterize the evolution of territorial space patterns from 1990 to 2020.A trend surface analysis and the Theil index were used to analyze regional differences in the evolution process,and geodetectors were used to identify the underlying mechanisms of the changes.There were three key results.(1)In these critical areas of the Pearl River Basin,agricultural and ecological spaces have rapidly declined due to urban expansion,with transfers between these spaces dominating the evolution of territorial space patterns.Spatial pattern changes in the Guangdong section were more intense than in the Guangxi section.(2)Regional differences in urban space have decreased,whereas differences in agricultural and ecological spaces have intensified.Driven by socio-economic growth,the cross-regional transfers of territorial space have created a“high in the east,while low in the west”inter-regional difference,and a“high in the south,while low in the north”intra-regional difference shaped by natural conditions.The regional differences in space patterns were greater in Guangdong than in Guangxi.(3)The evolution of watershed territorial space patterns resulted from scale changes,locational shifts,structural reorganizations,and directional changes driven by multiple factors.Natural environment,social life,economic development,and policy factors played foundational,leading,key driving,and guiding roles,respectively.Additionally,the regional differences in the evolution of watershed territorial space patterns originated from the differential transmission of the influence of various factors affecting spatial evolution.Enhancing urban space efficiency,restructuring agricultural space,and optimizing ecological space are key strategies for building a complementary and synergistic territorial space pattern in the basin.
基金supported by the Guangdong Basic and Applied Basic Research project (No.2020B0301030004)the Key-Area Research and Development Program of Guangdong Province (No.2020B1111360003)+1 种基金the National Natural Science Foundation of China (No.42105103)the Guangdong Basic and Applied Basic Research Foundation (No.2022A1515011554).
文摘Objective weather classification methods have been extensively applied to identify dominant ozone-favorable synoptic weather patterns(SWPs),however,the consistency of different classification methods is rarely examined.In this study,we apply two widely-used objective methods,the self-organizing map(SOM)and K-means clustering analysis,to derive ozone-favorable SWPs at four Chinese megacities in 2015-2022.We find that the two algorithms are largely consistent in recognizing dominant ozone-favorable SWPs for four Chinese megacities.In the case of classifying six SWPs,the derived circulation fields are highly similar with a spatial correlation of 0.99 between the two methods,and the difference in themean frequency of each SWP is less than 7%.The six dominant ozone-favorable SWPs in Guangzhou are all characterized by anomaly higher radiation and temperature,lower cloud cover,relative humidity,and wind speed,and stronger subsidence compared to climatology mean.We find that during 2015-2022,the occurrence of ozone-favorable SWPs days increases significantly at a rate of 3.2 days/year,faster than the increases in the ozone exceedance days(3.0 days/year).The interannual variability between the occurrence of ozone-favorable SWPs and ozone exceedance days are generally consistent with a temporal correlation coefficient of 0.6.In particular,the significant increase in ozone-favorable SWPs in 2022,especially the Subtropical High type which typically occurs in September,is consistent with a long-lasting ozone pollution episode in Guangzhou during September 2022.Our results thus reveal that enhanced frequency of ozone-favorable SWPs plays an important role in the observed 2015-2022 ozone increase in Guangzhou.
基金supported by the International Collaborative Research Program(fundamental research,2021-2023)funded by Korea Institute of Civil Engineering and Building Technology(KICT).
文摘Rock fractures or faults could be reactivated by the thermal stress generated during the decay process of the high-level radioactive waste in deep geological repositories(DGRs).Understanding thermoshearing behavior and its influencing factors are important for the long-term performance assessment of DGRs.We designed multistage mechanical(M)shear tests and thermomechanical(TM)shear tests on three 100 mm-cubic granite specimens,each containing a single inclined sawcut fracture with distinct microroughness of 8-15μm.M test results have shown that the static friction coefficient of the granite fracture decreases in proportion to the increase in the logarithm of the loading rate within the range of 1-15 kPa/s.For the given heating and boundary conditions,thermal loading rate,i.e.,thermal stress increment with heating time,is measured to be around 1 kPa/s in the fractured granite.Thermoshearing can be well predicted by the linear Mohr-Coulomb failure envelope deduced from M shear tests employing a loading rate that is comparable with the thermal loading rate.The granite fractures exhibited two distinct slip patterns during the mechanical shearing,i.e.,stick-slip observed in the smooth fracture and stable sliding in the relatively rough surface.In contrast,the mechanical loading rate(1-15 kPa/s)investigated in this study appears to not influence the slip pattern.Unlike those in M shear tests,thermoshearing in both smooth and relatively rough fractures show stable sliding with a very slow peak velocity of around 0.002μm/s.
基金Under the auspices of National Natural Science Foundation of China(No.42471205)the General Scientific Research Project of Zhejiang Provincial Department of Education(No.2024JYTYB12)the Philosophy and Social Science Planning Project of Zhejiang Province(No.23NDJC109YB)。
文摘In the era of the digital economy,digital trade has demonstrated strong vitality,becoming a crucial driving force for the highquality development of national and regional economies.However,understanding the resilience of digital trade in the face of external crises is an important topic.Taking the backdrop of Sino-US trade friction,this paper constructs a resilience index system for digital trade.It utilizes entropy method,kernel density estimation,and ArcGIS mapping to calculate and visually analyze the resilience of China’s digital trade from 2017 to 2021.Additionally,a Tobit model is constructed to explore the main influencing factors of digital trade resilience patterns.The research findings indicate:1)temporally,during the period of Sino-US trade friction,China’s digital trade resilience shows an overall upward trend,but there are regional differences in resilience levels across the country,with a severe polarization phenomenon.2)Spatially,high resilience is observed in the eastern and central regions of China,while the western and northeastern regions exhibit low resilience.3)From a dimensional perspective,the resistance of digital trade resilience displays a spatial distribution of high values in the east and low values in the west.The recovery force is aggregated along coastal areas,and the renewal force tends to aggregate along the eastern coastline.4)Factors such as economic scale,industrial structure,urbanization rate,government fiscal expenditure,and technological talents significantly promote the enhancement of digital trade resilience.This study reveals the dynamic characteristics and influencing factors of digital trade resilience in responding to external shocks,providing theoretical basis and policy suggestions for enhancing digital trade resilience,and promoting high-quality economic development in China.
文摘A custom micro-arc oxidation(MAO)apparatus is employed to produce coatings under optimized constant voltage–current two-step power supply mode.Various analytical techniques,including scanning electron microscopy,confocal laser microscopy,X-ray diffraction,X-ray photoelectron spectroscopy,transmission electron microscopy,and electrochemical analysis,are employed to characterize MAO coatings at different stages of preparation.MAO has MgO,hydroxyapatite,Ca_(3)(PO_(4))_(2),and Mg2SiO4 phases.Its microstructure of the coating is characterized by"multiple breakdowns,pores within pores",and"repaired blind pores".The porosity and the uniformity of MAO coating first declines in the constant voltage mode,then augments while the discharge phenomenon takes place,and finally decreases in the repair stage.These analyses reveal a four-stage growth pattern for MAO coatings:anodic oxidation stage,micro-arc oxidation stage,breakdown stage,and repairing stage.During anodic oxidation and MAO stages,inward growth prevails,while the breakdown stage sees outward and accelerated growth.Simultaneous inward and outward growth in the repair stage results in a denser,more uniform coating with increased thickness and improved corrosion resistance.
基金supported by the National Natural Science Foundation of China(No.U21B2062).
文摘The isolated fracture-vug systems controlled by small-scale strike-slip faults within ultra-deep carbonate rocks of the Tarim Basin exhibit significant exploration potential.The study employs a novel training set incorporating innovative fault labels to train a U-Net-structured CNN model,enabling effective identification of small-scale strike-slip faults through seismic data interpretation.Based on the CNN faults,we analyze the distribution patterns of small-scale strike-slip faults.The small-scale strike-slip faults can be categorized into NNW-trending and NE-trending groups with strike lengths ranging 200–5000 m.The development intensity of small-scale strike-slip faults in the Lower Yingshan Member notably exceeds that in the Upper Member.The Lower and Upper Yingshan members are two distinct mechanical layers with contrasting brittleness characteristics,separated by a low-brittleness layer.The superior brittleness of the Lower Yingshan Member enhances the development intensity of small-scale strike-slip faults compared to the upper member,while the low-brittleness layer exerts restrictive effects on vertical fault propagation.Fracture-vug systems formed by interactions of two or more small-scale strike-slip faults demonstrate larger sizes than those controlled by individual faults.All fracture-vug system sizes show positive correlations with the vertical extents of associated small-scale strike-slip faults,particularly intersection and approaching fracture-vug systems exhibit accelerated size increases proportional to the vertical extents.
基金the Basic Scientific Fund for National Public Research Institutes of China(No.2023Q03)the National Natural Science Foundation of China(Nos.42476078,42306091)+2 种基金the National Programme on Global Change and Air-Sea Interaction(Nos.GASI-04-HYDZ-02,GASI-02-SCS-CJB01)the China-Malaysia Cooperation Project‘Effect on Variability of Seasonal Monsoon on Sedimentary Process in Peninsular Malaysia Waters’the China-Thailand Cooperation Project‘Research on Vulnerability of Coastal Zone’。
文摘The transport of suspended particulate matter is a crucial aspect of studies on sediment source-to-sink processes.However,research on its transport patterns in high-erosion areas of low-latitude seas remains limited.To elucidate modern land-sea interaction processes controlled by the monsoon climate,this study investigates the seasonal transport patterns and control mechanisms of suspended particulate matter in the western Sunda Shelf.Results reveal significant seasonal variations in the spatial distribution of suspended particulate matter concentrations,with elevated levels observed during autumn compared with spring.These differences are directly attributed to the East Asian monsoon,including seasonal monsoon precipitation and the associated transport dynamics.During the northeast monsoon,the Malay Peninsula serves as a primary source for the western sea area,with terrestrial materials from its rivers transported to the northern Gulf of Thailand.This transport pattern shifts to an S-shaped,clockwise circulation during upwelling events.Conversely,in the southwest monsoon,rivers in the northern Gulf of Thailand become the predominant sources for the Sunda Shelf,with terrestrial materials carried by clockwise currents toward the eastern Malay Peninsula.When upwelling occurs off the southern Indochina Peninsula,one branch heads toward the South China Sea and the other toward the southern tip of the Malay Peninsula.The seasonal variation in material sources is further supported by the distribution of clay minerals and the discrimination results of rare earth element proxies,including(La/Sm)UCC-(Gd/Yb)UCCand(La/Yb)UCC-(Gd/Yb)UCC,in surface sediments from the Sunda Shelf and surrounding marine areas.
文摘Gastric cancer(GC)represents a significant global health burden due to its high morbidity and mortality.Specific behaviors of GC sub-types,distinct dissem-ination patterns,and associated risk-factors remain poorly understood.This editorial highlights several key prognostic factors,including pathological staging and vascular invasion,that impact GC.It examines a recent study’s investigation of differential metastatic lymph nodes distribution and survival in upper and lower GC sub-types,focusing on histological characterization,pathophysiology,usage of neoadjuvant chemotherapy,and additional predictive determinants.We assess the statistical robustness and clinical applicability of the findings,un-derscoring the importance of treating GC as a heterogeneous disease and em-phasizing how tailored surgical approaches informed by lymph node distribution can optimize tumor detection while minimizing unnecessary interventions.The study’s large cohort,multi-center design,and strict inclusion criteria strengthen its validity in guiding surgical planning and risk-stratification.However,inte-grating genetic and molecular data is critical for refining models and broadening applicability.Additionally,recurrence-metrics and infection-related factors,such as Helicobacter pylori and Epstein-Barr virus,absent in the original study,remain vital for directing future research.By bridging metastatic patterns with pros-pective methodologies and inclusion of diverse populations,this editorial pro-vides a framework for advancing early detection and personalized GC care.
文摘BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no research.AIM To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic intervention.METHODS A cross-sectional survey was disseminated among ophthalmologists all over India.The survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up patterns.RESULTS A total of 180 ophthalmologists responded to the survey.Most practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was advised.The most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid surgeries.Sixty-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease patients.CONCLUSION Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular conditions.Many ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract surgery.Eyelid conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.
文摘Chaoshan drawnwork handkerchief design exhibits self-similarity and fractal characteristics due to their grid-based structure,overall symmetry,and the way local motifs reflect the whole pattern.To explore the potential of fractals in traditional textile design,a fractal-based generative framework was proposed for efficiently creating drawnwork patterns suitable for practical handicraft production.The research was initiated with an analysis of the structural composition of center,skeleton,and filler motifs extracted from a pattern sample library.Based on this hierarchical classification,the box-counting method was employed to calculate their respective fractal dimensions.Building on fractal art theory,generative algorithms,and studies on the application of Ultra Fractal,a Chaoshan drawnwork fractal design model was established.Using this model,51 drawnwork fractal patterns and 153 handkerchief patterns were generated.These patterns were subsequently applied in real-world production to validate the feasibility and value of fractal techniques in textile design.
