The effect of ultrathin Fe layer on perpendicular magnetic anisotropy(PMA) in magnetron-sputtered Co/Pt multilayers was investigated by magnetic measurements.Magnetization hysteresis(M-H) loops and microstructures of ...The effect of ultrathin Fe layer on perpendicular magnetic anisotropy(PMA) in magnetron-sputtered Co/Pt multilayers was investigated by magnetic measurements.Magnetization hysteresis(M-H) loops and microstructures of the samples were measured by vibrating sample magnetometer(VSM) and X-ray diffraction(XRD) and highresolution transmission electron microscopy(HRTEM),respectively.It is found that the PMA is strongly dependent on the interface where Fe layer was doped.When Fe layer was doped at Co/Pt interface where Pt was deposited on Co,the PMA decreases monotonically with Fe layer thickness(tFe) increasing.However,when Fe layer was doped at Pt/Co interface where Co was deposited on Pt,the PMA shows a peak at t_(Fe)=0.1 nm.It is considered that the PMA variation is mainly due to the tuning in the electron occupation states of 3 d orbits at Fe-doped Pt/Co interface.Furthermore,the annealing stability of PMA can also be improved when Fe layer was doped at Pt/Co interface.HRTEM results demonstrate that the magnetic anisotropy evolution is mainly caused by anneal-induced interdiffusion.展开更多
Thanks to the strong perpendicular magnetic anisotropy(PMA), excellent processing compatibility as well as novel spintronic phenomenon, Co/Pt multilayers have been attracting massive attention and widely used in magne...Thanks to the strong perpendicular magnetic anisotropy(PMA), excellent processing compatibility as well as novel spintronic phenomenon, Co/Pt multilayers have been attracting massive attention and widely used in magnetic storage.However, reversed magnetic domains come into being with the increasing layer repetition ‘N’ to reduce magneto-static energy, resulting in the remarkable diminishment of the remanent magnetization(Mr). As a result, the product of Mrand thickness(i.e., the remanent moment-thickness product, Mrt), a key parameter in magnetic recording for reliable data storing and reading, also decreases dramatically. To overcome this issue, we deposit an ultra-thick granular [Co/Pt]80multilayer with a total thickness of 68 nm on granular SiNxbuffer layer. The Mrt value, Mrto saturation magnetization(Ms) ratio as well as out of plane(OOP) coercivity(Hcoop) are high up to 2.97 memu/cm^(2), 67%, and 1940 Oe(1 Oe = 79.5775 A·m^(-1)),respectively, which is remarkably improved compared with that of continuous [Co/Pt]80multilayers. That is because large amounts of grain boundaries in the granular multilayers can efficiently impede the propagation and expansion of reversed magnetic domains, which is verified by experimental investigations and micromagnetic simulation results. The simulation results also indicate that the value of Mrt, Mr/Msratio, and Hcoopcan be further improved through optimizing the granule size, which can be experimentally realized by manipulating the process parameter of SiNxbuffer layer. This work provides an alternative solution for achieving high Mrt value in ultra-thick Co/Pt multilayers, which is of unneglectable potential in applications of high-density magnetic recording.展开更多
Out-of-plane angular dependence of ferromagnetic resonance spectra was measured in sputtered Co/Pt multilayers and analyzed with the Landau-Lifshitz-Gilbert equation. The effective demagnetizing field 4πMeff is found...Out-of-plane angular dependence of ferromagnetic resonance spectra was measured in sputtered Co/Pt multilayers and analyzed with the Landau-Lifshitz-Gilbert equation. The effective demagnetizing field 4πMeff is found to increase with decreasing tPt and decreasing 1/tco, which can be considered as a result of interplay between the interlayer coupling and a lowdimensional effect. The g factor increases with increasing tpt and decreasing tCo, indicating contribution of spin-polarization of Pt atoms and additional contribution of orbital moment of Co atoms. The in-plane resonance line-width increases with decreasing too and increases with increasing tPt.展开更多
Co/Pt multilayers with perpendicular anisotropy were deposited using a dc magnetron sputtering system under high vacuum.Magnetization process was investigated by the measurement of magnetic components parallel and per...Co/Pt multilayers with perpendicular anisotropy were deposited using a dc magnetron sputtering system under high vacuum.Magnetization process was investigated by the measurement of magnetic components parallel and perpendicular to the applied field.A dependence of the coercivity of Co/Pt multilayers on the Co layer thickness was reported,in which the total thickness of Co layers kept constant.It is observed that the coercivity increases with the increment of Co layer thickness.For the samples with the same Co layer thickness while different total Co layer thickness,the coercivity first increases and then decreases with the increase of the total thickness of Co layers.This effect could be attributed to the competition between the reduction of HC related to incoherent reversal and the step-up of HC contributed by the magnetic polarization of Pt atoms at the interface of Co and Pt layers during magnetization reversal.The results show that the change of the coercivity is strongly related to the Co layer thickness,but not the total thickness of Co layers.The dependence of the coercivity on the angle between an applied field and the easy axis shows that the nucleation mode is dominant in magnetization reversal process of the samples.展开更多
[FePt/Ag]n multilayers were deposited on glass substrates by RF magnetron sputtering and ex situ annealed at 550℃ for 30 min. The effects of inserted Ag layer thickness and the number of bilayer repetitions （n） on ...[FePt/Ag]n multilayers were deposited on glass substrates by RF magnetron sputtering and ex situ annealed at 550℃ for 30 min. The effects of inserted Ag layer thickness and the number of bilayer repetitions （n） on the structure and magnetic properties of the multilayers were investigated. It was found that the difference between in-plane and out-of-plane coercivities varied with an increase of inserted Ag layer thickness in the [FePt 2 nm/Ag x nm]10 multilayers. The ratio of out-of-plane coercivity to in-plane coercivity reached the maximum value with the Ag layer thickness of 5 nm, indicating that the Ag layer thickness plays an important role in obtaining perpendicular orientation. For the [FePt 2 nm/Ag 5 um]n multilayers, perpendicular orientation is also influenced by n. The maximum value of the ratio of out-of-plane coercivity to in-plane coercivity appeared when n was given as 8. It was found that the [FePt 2 nm/Ag 5 nm]8 had a high perpendicular coercivity of 520 kA/m and a low in-plane one of 88 kA/m, which shows a strong perpendicular anisotropy.展开更多
Highly transparent indium-free composite electrodes of TiO2/Cu/TiO2 are deposited by electron-beam evaporation at room temperature. The effects of Cu thickness and annealing temperature on the electrical and optical p...Highly transparent indium-free composite electrodes of TiO2/Cu/TiO2 are deposited by electron-beam evaporation at room temperature. The effects of Cu thickness and annealing temperature on the electrical and optical properties of the multilayer film are investigated. The critical thickness of Cu mid-layer to form a continuous conducting layer is found to be 11 nm. The multilayer with a mid-Cu thickness of 11 nm is optimized to obtain a resistivity of 7.4× 10^- 5 Ω-cm and an average optical transmittance of 86% in the visible spectral range. The figure of merit of the TiO2/Cu（ 11 nm）/TiO2 multilayer annealed at 150℃ reaches a minimum resistivity of 5.9× 10^- 5 ℃.cm and an average optical transmittance of 88% in the visible spectral range. The experimental results indicate that TiO2/Cu/TiO2 multilayers can be used as a transparent electrode for solar cell and other display applications.展开更多
Based on a geology-engineering sweet spot evaluation,the high-quality reservoir zones and horizontal well landing points were determined.Subsequently,fracture propagation and production were simulated with a multilaye...Based on a geology-engineering sweet spot evaluation,the high-quality reservoir zones and horizontal well landing points were determined.Subsequently,fracture propagation and production were simulated with a multilayer fracturing scenario.The optimal hydraulic fracturing strategy for themultilayer fracturing networkwas determined by introducing a vertical asymmetry factor.This strategy aimed to minimize stress shadowing effects in the vertical direction while maximizing the stimulated reservoir volume(SRV).The study found that the small vertical layer spacing of high-quality reservoirs and the presence of stress-masking layers(with a stress difference of approximately 3∼8 MPa)indicate that interlayer stress interference from multilayers and multiwells fracturing between neighboring developed formations could affect the longitudinal propagation of the reservoirs.In addition,this study investigated well spacing optimization by comparing uniformly spaced wells(100–300 m)with asymmetric spaced wells(200 m upper layer,250 m lower layer).Numerical results indicated that asymmetric spaced well placement yielded the largest stimulated reservoir volume(SRV)of 73,082 m^(3),representing a 65.42%increase compared to 100 m spaced wells.Furthermore,four different hydraulic fracturing sequences(interlayer,up-down,down-up,and center-edge)were compared for multilayer and multiwell networks.The center-edge sequence exhibited the lowest vertical asymmetry factor(0.71)and the least stress shadowing effects compared to the other sequences(0.78 for interlayer,0.75 for up-down,and 0.76 for down-up).This sequence also achieved the largest SRV(486,194m^(3)),representing an 11.87%increase compared to the down-up sequence.Therefore,the center-edge fracturing sequence is recommended formultilayer development in this block.These results offer valuable insights for optimizing well placement and fracturing sequence design in multilayer well networks,ultimately advancing the development of multilayer fracturing technology in the region.展开更多
Electron doping has been established as an effective method to enhance the superconducting transition temperature and superconducting energy gap of FeSe thin films on strontium titanate(SrTiO_(3))substrates.Previous s...Electron doping has been established as an effective method to enhance the superconducting transition temperature and superconducting energy gap of FeSe thin films on strontium titanate(SrTiO_(3))substrates.Previous studies have demonstrated that electron/hole doping can be achieved through the adsorption of metal phthalocyanine(MPc,M=Co,Cu,Mn,Fe,and Ni)molecules on surfaces.This work explores the electron doping induced by the adsorption of MPc molecules,specifically cobalt phthalocyanine(CoPc)and copper phthalocyanine(CuPc),onto FeSe monolayer and multilayers.Utilizing first-principles calculations based on density functional theory,we demonstrate that charge rearrangement occurs when MPc molecules adsorb on the FeSe substrate,contributing to an accumulation of electrons at the interface.In the CoPc/FeSe systems,the electron accumulation increases with the layer number of FeSe substrate,converging for substrates with 3-5 layers.The analysis of the integrated planar charge difference up to the position with zero integrated charge transfer reveals that all the five MPc molecules donate electrons to the uppermost FeSe layer.The electron donation suggests that MPc adsorption can be a promising strategy to modulate the superconductivity of FeSe layers.展开更多
（Pt/Co）n/FeMn multilayers with perpendicular anisotropy （PA） were prepared by magnetron sputtering with Pt as the buffer layer and the capping layer. The dependence of perpendicular exchange bias （PEB）, Hex, on ...（Pt/Co）n/FeMn multilayers with perpendicular anisotropy （PA） were prepared by magnetron sputtering with Pt as the buffer layer and the capping layer. The dependence of perpendicular exchange bias （PEB）, Hex, on the thickness of the FeMn anfiferromagnet （AFM） layer is similar to that of in-plane exchange bias. The value of Hex for the （Pt/Co）3/FeMn multilayer reaches 22.3 kA/m. A thin Pt spacer was inserted between the Co/FeMn interface to enhance PEB. The PEB reaches the largest at 39.8 kA/m when the thickness of the Pt spacer is 0.4 nm.展开更多
Polyelectrolyte multilayers were self-assembled onto planar glass substrates and multimode optic fibers. The multilayer thin films deposited on glass substrates were characterized by using UV-vis spectroscopy and X-ra...Polyelectrolyte multilayers were self-assembled onto planar glass substrates and multimode optic fibers. The multilayer thin films deposited on glass substrates were characterized by using UV-vis spectroscopy and X-ray photoelectron spectroscope. The multilayer thin films containing hydrophilic side-groups possessed are affinity for uwer molecules. The adsorption and desorption of free water vapor gave rise to the changes in the refractive index and in the reflectance of the thin films. A multilayer thin film based fiber optic humidity sensor with an LED light source of 0.85 mum was designed. Under certain conditions, the rejected light intensity of the thin film sensor was a function of the humidity of air. About 30 bilayers was optimal for the multilayer thin film sensor working at wavelength of 0.85 mum. This sensor can work over almost the whole relative humidity range with very good sensitivity.展开更多
Objective:Prostate cancer(PCa)exhibits significant genomic differences between Western and Asian populations.This study aimed to design a predictive model applicable across diverse populations while selecting a limite...Objective:Prostate cancer(PCa)exhibits significant genomic differences between Western and Asian populations.This study aimed to design a predictive model applicable across diverse populations while selecting a limited set of genes suitable for clinical implementation.Methods:We utilized an integrated dataset of 1360 whole-exome and whole-genome sequences from Chinese and Western PCa cohorts to develop and evaluate the model.External validation was conducted using an independent cohort of patients.A graph neural network architecture,termed the pathway-aware multi-layered hierarchical network-Western and Asian(P-NETwa),was developed and trained on combined genomic profiles from Chinese and Western cohorts.The model employed a multilayer perceptron(MLP)to identify key signature genes from multiomics data,enabling precise prediction of PCa metastasis.Results:The model achieved an accuracy of 0.87 and an F1-score of 0.85 on Western population datasets.The application of integrated Chinese and Western population data improved the accuracy to 0.88,achieving an F1-score of 0.75.The analysis identified 18 signature genes implicated in PCa progression,including established markers(AR and TP53)and novel candidates(MUC16,MUC4,and ASB12).For clinical adoption,the model was optimized for commercially available gene panels while maintaining high classification accuracy.Additionally,a user-friendly web interface was developed to facilitate real-time prediction of primary versus metastatic status using the pre-trained P-NETwa-MLP model.Conclusion:The P-NETwa-MLP model integrates a query system that allows for efficient retrieval of prediction outcomes and associated genomic signatures via sample ID,enhancing its potential for seamless integration into clinical workflows.展开更多
FePt （50 nm） and [FePt（a nm）/MgO（b nm）5/glass （a=1, 2, 3; b=1, 2, 3） films were prepared by radio frequency （RF） magnetron sputtering technique, and then were annealed at 600℃ for 30 min. The effect of MgO ...FePt （50 nm） and [FePt（a nm）/MgO（b nm）5/glass （a=1, 2, 3; b=1, 2, 3） films were prepared by radio frequency （RF） magnetron sputtering technique, and then were annealed at 600℃ for 30 min. The effect of MgO layer thickness on the structures and magnetic properties of the FePt/MgO multilayers was investigated. The coercivities and inter-grain interactions of the FePt/MgO films were decreased, yet the degree of （001） texturing drastically increased with the increase in MgO layer thickness when the FePt layer thickness was fixed. Thus, the FePt/MgO films with appropriate coercivities, high perpendicular anisotropy, and weak intergrain interactions were obtained by controlling the MgO layer thickness. Overall, these results indicate that the FePt/MgO nanostructured films are promising candidates for future high-density perpendicular recording media.展开更多
基金financially supported by the National Natural Science Foundation of China (Nos.51371027 and 51331002)the National Key Scientific Research Projects of China (No.2015CB921502)the Ph.D.Programs Foundation of Ministry of Education (No.20120006130002)。
文摘The effect of ultrathin Fe layer on perpendicular magnetic anisotropy(PMA) in magnetron-sputtered Co/Pt multilayers was investigated by magnetic measurements.Magnetization hysteresis(M-H) loops and microstructures of the samples were measured by vibrating sample magnetometer(VSM) and X-ray diffraction(XRD) and highresolution transmission electron microscopy(HRTEM),respectively.It is found that the PMA is strongly dependent on the interface where Fe layer was doped.When Fe layer was doped at Co/Pt interface where Pt was deposited on Co,the PMA decreases monotonically with Fe layer thickness(tFe) increasing.However,when Fe layer was doped at Pt/Co interface where Co was deposited on Pt,the PMA shows a peak at t_(Fe)=0.1 nm.It is considered that the PMA variation is mainly due to the tuning in the electron occupation states of 3 d orbits at Fe-doped Pt/Co interface.Furthermore,the annealing stability of PMA can also be improved when Fe layer was doped at Pt/Co interface.HRTEM results demonstrate that the magnetic anisotropy evolution is mainly caused by anneal-induced interdiffusion.
基金supported by the National Natural Science Foundation of China (Grant No. 51901008)the National Key Research and Development Program of China (Grant No. 2021YFB3201800)。
文摘Thanks to the strong perpendicular magnetic anisotropy(PMA), excellent processing compatibility as well as novel spintronic phenomenon, Co/Pt multilayers have been attracting massive attention and widely used in magnetic storage.However, reversed magnetic domains come into being with the increasing layer repetition ‘N’ to reduce magneto-static energy, resulting in the remarkable diminishment of the remanent magnetization(Mr). As a result, the product of Mrand thickness(i.e., the remanent moment-thickness product, Mrt), a key parameter in magnetic recording for reliable data storing and reading, also decreases dramatically. To overcome this issue, we deposit an ultra-thick granular [Co/Pt]80multilayer with a total thickness of 68 nm on granular SiNxbuffer layer. The Mrt value, Mrto saturation magnetization(Ms) ratio as well as out of plane(OOP) coercivity(Hcoop) are high up to 2.97 memu/cm^(2), 67%, and 1940 Oe(1 Oe = 79.5775 A·m^(-1)),respectively, which is remarkably improved compared with that of continuous [Co/Pt]80multilayers. That is because large amounts of grain boundaries in the granular multilayers can efficiently impede the propagation and expansion of reversed magnetic domains, which is verified by experimental investigations and micromagnetic simulation results. The simulation results also indicate that the value of Mrt, Mr/Msratio, and Hcoopcan be further improved through optimizing the granule size, which can be experimentally realized by manipulating the process parameter of SiNxbuffer layer. This work provides an alternative solution for achieving high Mrt value in ultra-thick Co/Pt multilayers, which is of unneglectable potential in applications of high-density magnetic recording.
基金Project supported by the National Natural Science Foundation of China （Grant Nos.10504019, 10574087）, and the Shanghai Leading Academic Disciplines Program （Grant No.T0104）
文摘Out-of-plane angular dependence of ferromagnetic resonance spectra was measured in sputtered Co/Pt multilayers and analyzed with the Landau-Lifshitz-Gilbert equation. The effective demagnetizing field 4πMeff is found to increase with decreasing tPt and decreasing 1/tco, which can be considered as a result of interplay between the interlayer coupling and a lowdimensional effect. The g factor increases with increasing tpt and decreasing tCo, indicating contribution of spin-polarization of Pt atoms and additional contribution of orbital moment of Co atoms. The in-plane resonance line-width increases with decreasing too and increases with increasing tPt.
基金Projects(10574065,20833002) supported by the National Natural Science Foundation of ChinaProject(2009CB929503) supported by the National Basic Research Program of China
文摘Co/Pt multilayers with perpendicular anisotropy were deposited using a dc magnetron sputtering system under high vacuum.Magnetization process was investigated by the measurement of magnetic components parallel and perpendicular to the applied field.A dependence of the coercivity of Co/Pt multilayers on the Co layer thickness was reported,in which the total thickness of Co layers kept constant.It is observed that the coercivity increases with the increment of Co layer thickness.For the samples with the same Co layer thickness while different total Co layer thickness,the coercivity first increases and then decreases with the increase of the total thickness of Co layers.This effect could be attributed to the competition between the reduction of HC related to incoherent reversal and the step-up of HC contributed by the magnetic polarization of Pt atoms at the interface of Co and Pt layers during magnetization reversal.The results show that the change of the coercivity is strongly related to the Co layer thickness,but not the total thickness of Co layers.The dependence of the coercivity on the angle between an applied field and the easy axis shows that the nucleation mode is dominant in magnetization reversal process of the samples.
基金This work is financially supported by the National Natural Science Foundation of China (No. 10574085) Natural Science Foundation ofShanxi Province, China (No. 20041032).
文摘[FePt/Ag]n multilayers were deposited on glass substrates by RF magnetron sputtering and ex situ annealed at 550℃ for 30 min. The effects of inserted Ag layer thickness and the number of bilayer repetitions （n） on the structure and magnetic properties of the multilayers were investigated. It was found that the difference between in-plane and out-of-plane coercivities varied with an increase of inserted Ag layer thickness in the [FePt 2 nm/Ag x nm]10 multilayers. The ratio of out-of-plane coercivity to in-plane coercivity reached the maximum value with the Ag layer thickness of 5 nm, indicating that the Ag layer thickness plays an important role in obtaining perpendicular orientation. For the [FePt 2 nm/Ag 5 um]n multilayers, perpendicular orientation is also influenced by n. The maximum value of the ratio of out-of-plane coercivity to in-plane coercivity appeared when n was given as 8. It was found that the [FePt 2 nm/Ag 5 nm]8 had a high perpendicular coercivity of 520 kA/m and a low in-plane one of 88 kA/m, which shows a strong perpendicular anisotropy.
基金Project supported by the Research Innovation Key Project of Education Committee of Shanghai,China(Grant No.14ZZ137)the National Cultivation Fund from University of Shanghai for Science and Technology(Grant No.14XPM04)
文摘Highly transparent indium-free composite electrodes of TiO2/Cu/TiO2 are deposited by electron-beam evaporation at room temperature. The effects of Cu thickness and annealing temperature on the electrical and optical properties of the multilayer film are investigated. The critical thickness of Cu mid-layer to form a continuous conducting layer is found to be 11 nm. The multilayer with a mid-Cu thickness of 11 nm is optimized to obtain a resistivity of 7.4× 10^- 5 Ω-cm and an average optical transmittance of 86% in the visible spectral range. The figure of merit of the TiO2/Cu（ 11 nm）/TiO2 multilayer annealed at 150℃ reaches a minimum resistivity of 5.9× 10^- 5 ℃.cm and an average optical transmittance of 88% in the visible spectral range. The experimental results indicate that TiO2/Cu/TiO2 multilayers can be used as a transparent electrode for solar cell and other display applications.
基金supported by the National Natural Science Foundation of China(51704324,52374027)Shandong Natural Science Foundation of China(ZR2022ME025,ZR2023ME158).
文摘Based on a geology-engineering sweet spot evaluation,the high-quality reservoir zones and horizontal well landing points were determined.Subsequently,fracture propagation and production were simulated with a multilayer fracturing scenario.The optimal hydraulic fracturing strategy for themultilayer fracturing networkwas determined by introducing a vertical asymmetry factor.This strategy aimed to minimize stress shadowing effects in the vertical direction while maximizing the stimulated reservoir volume(SRV).The study found that the small vertical layer spacing of high-quality reservoirs and the presence of stress-masking layers(with a stress difference of approximately 3∼8 MPa)indicate that interlayer stress interference from multilayers and multiwells fracturing between neighboring developed formations could affect the longitudinal propagation of the reservoirs.In addition,this study investigated well spacing optimization by comparing uniformly spaced wells(100–300 m)with asymmetric spaced wells(200 m upper layer,250 m lower layer).Numerical results indicated that asymmetric spaced well placement yielded the largest stimulated reservoir volume(SRV)of 73,082 m^(3),representing a 65.42%increase compared to 100 m spaced wells.Furthermore,four different hydraulic fracturing sequences(interlayer,up-down,down-up,and center-edge)were compared for multilayer and multiwell networks.The center-edge sequence exhibited the lowest vertical asymmetry factor(0.71)and the least stress shadowing effects compared to the other sequences(0.78 for interlayer,0.75 for up-down,and 0.76 for down-up).This sequence also achieved the largest SRV(486,194m^(3)),representing an 11.87%increase compared to the down-up sequence.Therefore,the center-edge fracturing sequence is recommended formultilayer development in this block.These results offer valuable insights for optimizing well placement and fracturing sequence design in multilayer well networks,ultimately advancing the development of multilayer fracturing technology in the region.
基金support from the National Natural Science Foundation of China(Grant No.62488201)the National Key Research and Development Program of China(Grant No.2022YFA1204100).
文摘Electron doping has been established as an effective method to enhance the superconducting transition temperature and superconducting energy gap of FeSe thin films on strontium titanate(SrTiO_(3))substrates.Previous studies have demonstrated that electron/hole doping can be achieved through the adsorption of metal phthalocyanine(MPc,M=Co,Cu,Mn,Fe,and Ni)molecules on surfaces.This work explores the electron doping induced by the adsorption of MPc molecules,specifically cobalt phthalocyanine(CoPc)and copper phthalocyanine(CuPc),onto FeSe monolayer and multilayers.Utilizing first-principles calculations based on density functional theory,we demonstrate that charge rearrangement occurs when MPc molecules adsorb on the FeSe substrate,contributing to an accumulation of electrons at the interface.In the CoPc/FeSe systems,the electron accumulation increases with the layer number of FeSe substrate,converging for substrates with 3-5 layers.The analysis of the integrated planar charge difference up to the position with zero integrated charge transfer reveals that all the five MPc molecules donate electrons to the uppermost FeSe layer.The electron donation suggests that MPc adsorption can be a promising strategy to modulate the superconductivity of FeSe layers.
基金This work was financially supported by the National Natural Science Foundation of China (No.50471093)the Science Founda-tion of Beijing (No.2052014)
文摘（Pt/Co）n/FeMn multilayers with perpendicular anisotropy （PA） were prepared by magnetron sputtering with Pt as the buffer layer and the capping layer. The dependence of perpendicular exchange bias （PEB）, Hex, on the thickness of the FeMn anfiferromagnet （AFM） layer is similar to that of in-plane exchange bias. The value of Hex for the （Pt/Co）3/FeMn multilayer reaches 22.3 kA/m. A thin Pt spacer was inserted between the Co/FeMn interface to enhance PEB. The PEB reaches the largest at 39.8 kA/m when the thickness of the Pt spacer is 0.4 nm.
基金Funded by the Natural Science Foundation of Hubei Prov-ince (No. 2000J002)
文摘Polyelectrolyte multilayers were self-assembled onto planar glass substrates and multimode optic fibers. The multilayer thin films deposited on glass substrates were characterized by using UV-vis spectroscopy and X-ray photoelectron spectroscope. The multilayer thin films containing hydrophilic side-groups possessed are affinity for uwer molecules. The adsorption and desorption of free water vapor gave rise to the changes in the refractive index and in the reflectance of the thin films. A multilayer thin film based fiber optic humidity sensor with an LED light source of 0.85 mum was designed. Under certain conditions, the rejected light intensity of the thin film sensor was a function of the humidity of air. About 30 bilayers was optimal for the multilayer thin film sensor working at wavelength of 0.85 mum. This sensor can work over almost the whole relative humidity range with very good sensitivity.
基金supported by the National Key R&D Program of China(2022YFA1305700 to Li J)the“Dawn”Program of Shanghai Education Commission,China(21SG33 to Li J)The National Natural Science Foundation of China(82272793 to Gao X).
文摘Objective:Prostate cancer(PCa)exhibits significant genomic differences between Western and Asian populations.This study aimed to design a predictive model applicable across diverse populations while selecting a limited set of genes suitable for clinical implementation.Methods:We utilized an integrated dataset of 1360 whole-exome and whole-genome sequences from Chinese and Western PCa cohorts to develop and evaluate the model.External validation was conducted using an independent cohort of patients.A graph neural network architecture,termed the pathway-aware multi-layered hierarchical network-Western and Asian(P-NETwa),was developed and trained on combined genomic profiles from Chinese and Western cohorts.The model employed a multilayer perceptron(MLP)to identify key signature genes from multiomics data,enabling precise prediction of PCa metastasis.Results:The model achieved an accuracy of 0.87 and an F1-score of 0.85 on Western population datasets.The application of integrated Chinese and Western population data improved the accuracy to 0.88,achieving an F1-score of 0.75.The analysis identified 18 signature genes implicated in PCa progression,including established markers(AR and TP53)and novel candidates(MUC16,MUC4,and ASB12).For clinical adoption,the model was optimized for commercially available gene panels while maintaining high classification accuracy.Additionally,a user-friendly web interface was developed to facilitate real-time prediction of primary versus metastatic status using the pre-trained P-NETwa-MLP model.Conclusion:The P-NETwa-MLP model integrates a query system that allows for efficient retrieval of prediction outcomes and associated genomic signatures via sample ID,enhancing its potential for seamless integration into clinical workflows.
基金This work was financially supported by the National Natural Science Foundation of China (No.10574085)the Opening Foundation of the Key Laboratory of Shanxi Province (200503010)the Key Project of the Ministry of Education of China (No.207020).
文摘FePt （50 nm） and [FePt（a nm）/MgO（b nm）5/glass （a=1, 2, 3; b=1, 2, 3） films were prepared by radio frequency （RF） magnetron sputtering technique, and then were annealed at 600℃ for 30 min. The effect of MgO layer thickness on the structures and magnetic properties of the FePt/MgO multilayers was investigated. The coercivities and inter-grain interactions of the FePt/MgO films were decreased, yet the degree of （001） texturing drastically increased with the increase in MgO layer thickness when the FePt layer thickness was fixed. Thus, the FePt/MgO films with appropriate coercivities, high perpendicular anisotropy, and weak intergrain interactions were obtained by controlling the MgO layer thickness. Overall, these results indicate that the FePt/MgO nanostructured films are promising candidates for future high-density perpendicular recording media.
