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毛竹CLCs基因家族鉴定及高盐与干旱胁迫下的表达模式分析
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作者 陈诗蕾 郭琳 +2 位作者 鲁海雯 叶晓莉 林新春 《核农学报》 北大核心 2025年第11期2374-2387,共14页
氯离子通道蛋白(CLC)是一类介导以Cl-为代表的阴离子跨膜转运的重要通道或转运蛋白家族,在高盐与干旱胁迫等多种非生物胁迫中发挥重要作用。为探究毛竹CLCs基因家族的功能,本研究通过生物信息学方法对毛竹CLCs基因家族成员进行鉴定与分... 氯离子通道蛋白(CLC)是一类介导以Cl-为代表的阴离子跨膜转运的重要通道或转运蛋白家族,在高盐与干旱胁迫等多种非生物胁迫中发挥重要作用。为探究毛竹CLCs基因家族的功能,本研究通过生物信息学方法对毛竹CLCs基因家族成员进行鉴定与分析,利用RNA-Seq测序和实时荧光定量PCR(qRT-PCR)技术对高盐与干旱因子胁迫下CLCs基因的表达情况进行分析。结果表明,在毛竹全基因组中共鉴定到18条CLCs基因,这些基因编码蛋白长度为455~1440 aa,分子量为49358.04~157276.61 Da,理论等电点为6.40~8.85。系统进化分析表明,18条PeCLCs基因分为2个亚类,6个亚家族,且同一亚家族在基因结构方面具有相似性。共线性分析得出CLCs基因家族在毛竹中共有9个共线性基因对,且非同义突变率/同义突变率(Ka/Ks)值均小于1。启动子顺式元件结果显示,PeCLCs基因的启动子序列中含有胁迫响应、激素响应等多种元件。转录组数据分析结果显示,PeCLCs基因存在组织与其发育阶段特异性,大部分毛竹PeCLCs基因在鞭根系统与不同发育时期的竹笋中相对高表达,表明PeCLCs可在鞭根系统和竹笋快速生长过程中维持Cl-稳态。qRT-PCR结果显示,大部分PeCLCs在高盐与干旱胁迫条件下被诱导表达,说明PeCLCs可响应高盐与干旱胁迫。本研究结果为毛竹CLCs基因家族功能的进一步研究提供了参考依据与基因资源。 展开更多
关键词 毛竹 clc基因家族 生物信息学 高盐胁迫 干旱胁迫
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基于预训练语言模型的IPC与高相似CLC类目自动映射 被引量:1
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作者 黄敏 魏嘉琴 李茂西 《中文信息学报》 北大核心 2025年第2期153-161,共9页
专利和图书期刊是产业界与学术界的科技创新信息来源,专利通常采用国际专利分类法(International Patent Classification,IPC)标识,而中文图书期刊则采用中国图书馆分类法(Chinese Library Classification,CLC),不同的分类标识体系给专... 专利和图书期刊是产业界与学术界的科技创新信息来源,专利通常采用国际专利分类法(International Patent Classification,IPC)标识,而中文图书期刊则采用中国图书馆分类法(Chinese Library Classification,CLC),不同的分类标识体系给专利、图书期刊信息整合共享和跨库检索浏览带来了挑战。针对IPC类目和高相似的CLC类目难以准确映射的问题,对于计算资源受限的场景,该文提出结合预训练语言模型BERT和文本蕴含模型ESIM的IPC与CLC类目自动映射方法;对于计算资源充足的场景,该文提出了基于大语言模型ChatGLM2-6B的IPC与CLC类目自动映射方法。在公开的IPC与CLC类目映射数据集和在其基础上构建的IPC类目与高相似的CLC类目映射数据集上的实验结果表明,该文所提出的两种方法均统计显著地优于对比的基线方法,包括当前最先进的Sia-BERT等基于深度神经网络的科技文献类目自动映射方法。消融实验和详细的映射实例分析进一步揭示了该文所提方法的有效性。 展开更多
关键词 国际专利分类法 中国图书馆分类法 预训练语言模型 大语言模型 类目映射
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ERα和ClC-3的周期性表达与他莫昔芬抗乳腺癌作用的相关性研究
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作者 李雪苛 侯秀颖 +3 位作者 刘世情 杨海峰 朱林燕 何伟丽 《中国病理生理杂志》 北大核心 2025年第3期417-426,共10页
目的:探讨雌激素受体α(ERα)和ClC-3氯通道的周期性表达、分布和相互作用及其与他莫昔芬(TAM)抗乳腺癌周期特异性的相关性。方法:通过网络数据库分析ERα与ClC-3的表达相关性,三维分子模拟软件和免疫共沉淀法分析ERα和ClC-3的蛋白间... 目的:探讨雌激素受体α(ERα)和ClC-3氯通道的周期性表达、分布和相互作用及其与他莫昔芬(TAM)抗乳腺癌周期特异性的相关性。方法:通过网络数据库分析ERα与ClC-3的表达相关性,三维分子模拟软件和免疫共沉淀法分析ERα和ClC-3的蛋白间相互作用;胸腺嘧啶脱氧核苷(TdR)双阻断释放法和诺考达唑阻滞细胞周期,流式细胞术检测细胞周期;MTT法检测细胞活力;Western blot检测ERα和ClC-3的蛋白表达;免疫荧光染色检测ERα和ClC-3的亚细胞分布。结果:(1)网络数据库分析表明,ERα和ClC-3的表达显著相关;免疫共沉淀实验显示这两种蛋白存在相互作用;(2)使用TdR双阻断释放法和诺考达唑获得不同周期的人乳腺癌T47D细胞;(3)TAM对G2/M期的细胞活力抑制作用最强;(4)ERα和ClC-3的蛋白表达均有周期差异,且二者亚细胞分布存在周期性特点并表现为共定位;(5)ERα和ClC-3在各周期均存在蛋白间的相互作用;(6)TAM作用于各周期细胞后,处于G2/M期细胞的ERα蛋白表达最高,但对ClC-3在各周期的表达无显著影响。结论:人乳腺癌T47D细胞中ERα和ClC-3的表达和分布存在周期差异性,并且ERα和ClC-3存在蛋白间的相互作用;ERα的周期特性可能介导了TAM的抗乳腺癌作用周期特异性。 展开更多
关键词 乳腺癌 雌激素受体Α clc-3氯通道 他莫昔芬 细胞周期
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“CLC”:《中国图书馆分类法=Chinese Library Classification》语种代码
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《应用与环境生物学报》 CAS CSCD 北大核心 2005年第1期27-27,共1页
从2000年第1期起,本刊正式用“CLC”作为《中国图书馆分类法》分类标引符号的语种代码.本刊编辑部曾在专文[见:我国期刊论文分类标引问题面面观孙二虎//编辑学报,1999,11(1):4~8]中论及我国缺乏类似“UDC”、“DDC”之类的分... 从2000年第1期起,本刊正式用“CLC”作为《中国图书馆分类法》分类标引符号的语种代码.本刊编辑部曾在专文[见:我国期刊论文分类标引问题面面观孙二虎//编辑学报,1999,11(1):4~8]中论及我国缺乏类似“UDC”、“DDC”之类的分类语种专用代号的不便,并“盼望中国期刊界尽快得到分类语种代码的法定或约定的统一形式”.现在这一问题事实上已经得到解决:第四版《中国图书馆分类法》(内容上涵盖了详简不同的四种版本, 展开更多
关键词 《中国图书馆分类法》 语种代码 clc”标识 分类标引符号
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拟南芥过表达杉木ClC3HDZ1基因及其对缺磷胁迫的响应
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作者 黄朝章 赵紫宇 +3 位作者 曾一帆 叶小鹏 马祥庆 帅鹏 《森林与环境学报》 北大核心 2025年第5期501-508,共8页
为探究杉木ClC3HDZ1转录因子响应缺磷胁迫的作用机制。通过构建杉木ClC3HDZ1转录因子过表达拟南芥植株,研究其对缺磷胁迫的响应,提取杉木叶片中的总RNA并将其反转为cDNA,利用三步法聚合酶链式反应(PCR)扩增出ClC3HDZ1转录因子的编码序... 为探究杉木ClC3HDZ1转录因子响应缺磷胁迫的作用机制。通过构建杉木ClC3HDZ1转录因子过表达拟南芥植株,研究其对缺磷胁迫的响应,提取杉木叶片中的总RNA并将其反转为cDNA,利用三步法聚合酶链式反应(PCR)扩增出ClC3HDZ1转录因子的编码序列片段,连接至带有35S启动子驱动的PCAMBIA1300载体,转化到农杆菌,通过花序侵染法导入野生型拟南芥植株。经含有潮霉素的MS固体培养基筛选和PCR鉴定获得过表达植株,培养至T_(3)代。将T_(3)代过表达杉木ClC3HDZ1基因植株和野生型植株分别在缺磷和正常磷条件下垂直培养,观察测定不同植株的根长,测定不同植株组织总磷含量、花青素相对含量及叶绿素含量。结果表明:缺磷培养下,过表达植株根长受抑制程度小于野生型,且组织总磷含量高于野生型,花青素相对含量和叶绿素含量均低于野生型。杉木ClC3HDZ1基因异源过表达可促进拟南芥植株体内总磷的积累,抵抗缺磷胁迫,同时使拟南芥叶片中花青素增幅减小。 展开更多
关键词 杉木 clc3HDZ1基因 拟南芥 过表达 缺磷胁迫
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Urban tree species classification based on multispectral airborne LiDAR 被引量:1
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作者 HU Pei-Lun CHEN Yu-Wei +3 位作者 Mohammad Imangholiloo Markus Holopainen WANG Yi-Cheng Juha Hyyppä 《红外与毫米波学报》 北大核心 2025年第2期211-216,共6页
Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services... Urban tree species provide various essential ecosystem services in cities,such as regulating urban temperatures,reducing noise,capturing carbon,and mitigating the urban heat island effect.The quality of these services is influenced by species diversity,tree health,and the distribution and the composition of trees.Traditionally,data on urban trees has been collected through field surveys and manual interpretation of remote sensing images.In this study,we evaluated the effectiveness of multispectral airborne laser scanning(ALS)data in classifying 24 common urban roadside tree species in Espoo,Finland.Tree crown structure information,intensity features,and spectral data were used for classification.Eight different machine learning algorithms were tested,with the extra trees(ET)algorithm performing the best,achieving an overall accuracy of 71.7%using multispectral LiDAR data.This result highlights that integrating structural and spectral information within a single framework can improve the classification accuracy.Future research will focus on identifying the most important features for species classification and developing algorithms with greater efficiency and accuracy. 展开更多
关键词 multispectral airborne LiDAR machine learning tree species classification
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引入源端信息的IPC和CLC类目自动映射研究
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作者 钟易佳 李茂西 +2 位作者 王倩 黄琪 何彦青 《中文信息学报》 北大核心 2025年第3期159-168,共10页
国际专利分类法(International Patent Classification,IPC)是专利文献分类和检索的国际标准;中国图书馆分类法(Chinese library classification,CLC)是我国图书期刊的大型综合性分类法。自动准确地建立IPC类目和CLC类目之间的映射对实... 国际专利分类法(International Patent Classification,IPC)是专利文献分类和检索的国际标准;中国图书馆分类法(Chinese library classification,CLC)是我国图书期刊的大型综合性分类法。自动准确地建立IPC类目和CLC类目之间的映射对实现专利文献和图书期刊文献的跨库检索和交叉浏览有着重要的意义。针对当前研究中仅使用IPC中文译本类目描述文本来建立其与CLC类目之间的映射,完全忽略IPC原版英语类目描述文本信息的不足,该文提出了一种基于神经网络的IPC和CLC类目自动映射方法,通过引入源端信息(英语端信息)实现自动映射。首先分别通过预训练语言模型BERT和XLM-R生成IPC类目描述文本和CLC类目描述文本的词表征;然后利用多头注意力机制融合IPC类目的BERT模型词表征和XLM-R模型词表征,以及CLC类目的BERT模型词表征和XLM-R模型词表征,最后使用两个前馈神经网络层建立IPC类目和CLC类目之间的映射。在公开数据集上的实验结果表明,该文提出的方法显著优于当前最优方法,且其性能更稳定、泛化性更强。 展开更多
关键词 国际专利分类法 中国图书馆分类法 BERT XLM-R 多头注意力机制
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Impact of classification granularity on interdisciplinary performance assessment of research institutes and organizations 被引量:1
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作者 Jiandong Zhang Sonia Gruber Rainer Frietsch 《Journal of Data and Information Science》 2025年第2期61-79,共19页
Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interd... Purpose:Interdisciplinary research has become a critical approach to addressing complex societal,economic,technological,and environmental challenges,driving innovation and integrating scientific knowledge.While interdisciplinarity indicators are widely used to evaluate research performance,the impact of classification granularity on these assessments remains underexplored.Design/methodology/approach:This study investigates how different levels of classification granularity-macro,meso,and micro-affect the evaluation of interdisciplinarity in research institutes.Using a dataset of 262 institutes from four major German non-university organizations(FHG,HGF,MPG,WGL)from 2018 to 2022,we examine inconsistencies in interdisciplinarity across levels,analyze ranking changes,and explore the influence of institutional fields and research focus(applied vs.basic).Findings:Our findings reveal significant inconsistencies in interdisciplinarity across classification levels,with rankings varying substantially.Notably,the Fraunhofer Society(FHG),which performs well at the macro level,experiences significant ranking declines at meso and micro levels.Normalizing interdisciplinarity by research field confirmed that these declines persist.The research focus of institutes,whether applied,basic,or mixed,does not significantly explain the observed ranking dynamics.Research limitations:This study has only considered the publication-based dimension of institutional interdisciplinarity and has not explored other aspects.Practical implications:The findings provide insights for policymakers,research managers,and scholars to better interpret interdisciplinarity metrics and support interdisciplinary research effectively.Originality/value:This study underscores the critical role of classification granularity in interdisciplinarity assessment and emphasizes the need for standardized approaches to ensure robust and fair evaluations. 展开更多
关键词 Interdisciplinarity Paper-level classification system Organization evaluation
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YOLOCSP-PEST for Crops Pest Localization and Classification 被引量:1
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作者 Farooq Ali Huma Qayyum +2 位作者 Kashif Saleem Iftikhar Ahmad Muhammad Javed Iqbal 《Computers, Materials & Continua》 2025年第2期2373-2388,共16页
Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome... Preservation of the crops depends on early and accurate detection of pests on crops as they cause several diseases decreasing crop production and quality. Several deep-learning techniques have been applied to overcome the issue of pest detection on crops. We have developed the YOLOCSP-PEST model for Pest localization and classification. With the Cross Stage Partial Network (CSPNET) backbone, the proposed model is a modified version of You Only Look Once Version 7 (YOLOv7) that is intended primarily for pest localization and classification. Our proposed model gives exceptionally good results under conditions that are very challenging for any other comparable models especially conditions where we have issues with the luminance and the orientation of the images. It helps farmers working out on their crops in distant areas to determine any infestation quickly and accurately on their crops which helps in the quality and quantity of the production yield. The model has been trained and tested on 2 datasets namely the IP102 data set and a local crop data set on both of which it has shown exceptional results. It gave us a mean average precision (mAP) of 88.40% along with a precision of 85.55% and a recall of 84.25% on the IP102 dataset meanwhile giving a mAP of 97.18% on the local data set along with a recall of 94.88% and a precision of 97.50%. These findings demonstrate that the proposed model is very effective in detecting real-life scenarios and can help in the production of crops improving the yield quality and quantity at the same time. 展开更多
关键词 Deep learning classification of pests YOLOCSP-PEST pest detection
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Nondestructive detection and classification of impurities-containing seed cotton based on hyperspectral imaging and one-dimensional convolutional neural network 被引量:1
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作者 Yeqi Fei Zhenye Li +2 位作者 Tingting Zhu Zengtao Chen Chao Ni 《Digital Communications and Networks》 2025年第2期308-316,共9页
The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textile... The cleanliness of seed cotton plays a critical role in the pre-treatment of cotton textiles,and the removal of impurity during the harvesting process directly determines the quality and market value of cotton textiles.By fusing band combination optimization with deep learning,this study aims to achieve more efficient and accurate detection of film impurities in seed cotton on the production line.By applying hyperspectral imaging and a one-dimensional deep learning algorithm,we detect and classify impurities in seed cotton after harvest.The main categories detected include pure cotton,conveyor belt,film covering seed cotton,and film adhered to the conveyor belt.The proposed method achieves an impurity detection rate of 99.698%.To further ensure the feasibility and practical application potential of this strategy,we compare our results against existing mainstream methods.In addition,the model shows excellent recognition performance on pseudo-color images of real samples.With a processing time of 11.764μs per pixel from experimental data,it shows a much improved speed requirement while maintaining the accuracy of real production lines.This strategy provides an accurate and efficient method for removing impurities during cotton processing. 展开更多
关键词 Seed cotton Film impurity Hyperspectral imaging Band optimization classification
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Multi-Scale Dilated Convolution Network for SPECT-MPI Cardiovascular Disease Classification with Adaptive Denoising and Attenuation Correction
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作者 A.Robert Singh Suganya Athisayamani +1 位作者 Gyanendra Prasad Joshi Bhanu Shrestha 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期299-327,共29页
Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronar... Myocardial perfusion imaging(MPI),which uses single-photon emission computed tomography(SPECT),is a well-known estimating tool for medical diagnosis,employing the classification of images to show situations in coronary artery disease(CAD).The automatic classification of SPECT images for different techniques has achieved near-optimal accuracy when using convolutional neural networks(CNNs).This paper uses a SPECT classification framework with three steps:1)Image denoising,2)Attenuation correction,and 3)Image classification.Image denoising is done by a U-Net architecture that ensures effective image denoising.Attenuation correction is implemented by a convolution neural network model that can remove the attenuation that affects the feature extraction process of classification.Finally,a novel multi-scale diluted convolution(MSDC)network is proposed.It merges the features extracted in different scales and makes the model learn the features more efficiently.Three scales of filters with size 3×3 are used to extract features.All three steps are compared with state-of-the-art methods.The proposed denoising architecture ensures a high-quality image with the highest peak signal-to-noise ratio(PSNR)value of 39.7.The proposed classification method is compared with the five different CNN models,and the proposed method ensures better classification with an accuracy of 96%,precision of 87%,sensitivity of 87%,specificity of 89%,and F1-score of 87%.To demonstrate the importance of preprocessing,the classification model was analyzed without denoising and attenuation correction. 展开更多
关键词 SPECT-MPI CAD MSDC DENOISING attenuation correction classification
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Automated ECG arrhythmia classification using hybrid CNN-SVM architectures 被引量:1
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作者 Amine Ben Slama Yessine Amri +1 位作者 Ahmed Fnaiech Hanene Sahli 《Journal of Electronic Science and Technology》 2025年第3期43-55,共13页
Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advanc... Diagnosing cardiac diseases relies heavily on electrocardiogram(ECG)analysis,but detecting myocardial infarction-related arrhythmias remains challenging due to irregular heartbeats and signal variations.Despite advancements in machine learning,achieving both high accuracy and low computational cost for arrhythmia classification remains a critical issue.Computer-aided diagnosis systems can play a key role in early detection,reducing mortality rates associated with cardiac disorders.This study proposes a fully automated approach for ECG arrhythmia classification using deep learning and machine learning techniques to improve diagnostic accuracy while minimizing processing time.The methodology consists of three stages:1)preprocessing,where ECG signals undergo noise reduction and feature extraction;2)feature Identification,where deep convolutional neural network(CNN)blocks,combined with data augmentation and transfer learning,extract key parameters;3)classification,where a hybrid CNN-SVM model is employed for arrhythmia recognition.CNN-extracted features were fed into a binary support vector machine(SVM)classifier,and model performance was assessed using five-fold cross-validation.Experimental findings demonstrated that the CNN2 model achieved 85.52%accuracy,while the hybrid CNN2-SVM approach significantly improved accuracy to 97.33%,outperforming conventional methods.This model enhances classification efficiency while reducing computational complexity.The proposed approach bridges the gap between accuracy and processing speed in ECG arrhythmia classification,offering a promising solution for real-time clinical applications.Its superior performance compared to nonlinear classifiers highlights its potential for improving automated cardiac diagnosis. 展开更多
关键词 ARRHYTHMIA classification Convolutional neural networks ECG signals Support vector machine
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ClC-7在肺泡Ⅱ型细胞板层小体生物发生过程中的作用
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作者 周子旋 郝振华 李巍 《医学分子生物学杂志》 2025年第6期531-538,共8页
目的探究ClC-7在板层小体(lamellar body,LB)生物发生过程中的作用以及ClC-7突变体的可能致病机制。方法使用si RNA降低A549细胞内ClC-7的表达,利用激光共聚焦显微镜以及透射电子显微镜来观察LB的形态变化。构建ClC-7野生型以及突变体质... 目的探究ClC-7在板层小体(lamellar body,LB)生物发生过程中的作用以及ClC-7突变体的可能致病机制。方法使用si RNA降低A549细胞内ClC-7的表达,利用激光共聚焦显微镜以及透射电子显微镜来观察LB的形态变化。构建ClC-7野生型以及突变体质粒,观察ClC-7与LB以及其他细胞器的共定位情况。结果ClC-7定位于LB以及溶酶体上。敲降ClC-7后的A549细胞LB体积增大。p.G203D、p.G215R、p.G292E、p.R403Q、p.L766P突变后的ClC-7主要定位到内质网,但p.P470L突变后ClC-7可以部分转运至LB。结论A549细胞中ClC-7定位于LB与溶酶体。敲降ClC-7后LB的体积显著增大,结构异常。突变后的ClC-7多数不能正确定位在LB以及溶酶体上。 展开更多
关键词 clc-7 板层小体 溶酶体相关细胞器 肺泡Ⅱ型细胞 间质性肺病
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Various classification methods for diabetes mellitus in the management of blood glucose control 被引量:1
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作者 Qing Jiang Yun Hu Jian-Hua Ma 《World Journal of Diabetes》 2025年第5期1-7,共7页
In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in spec... In the era of precision medicine,the classification of diabetes mellitus has evolved beyond the traditional categories.Various classification methods now account for a multitude of factors,including variations in specific genes,type ofβ-cell impairment,degree of insulin resistance,and clinical characteristics of metabolic profiles.Improved classification methods enable healthcare providers to formulate blood glucose management strategies more precisely.Applying these updated classification systems,will assist clinicians in further optimising treatment plans,including targeted drug therapies,personalized dietary advice,and specific exercise plans.Ultimately,this will facilitate stricter blood glucose control,minimize the risks of hypoglycaemia and hyperglycaemia,and reduce long-term complications associated with diabetes. 展开更多
关键词 Diabetes classification Glycaemic control Personalised treatment Soft clustering Precision medicine
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Classification and provenance of exotic impact glasses in Chang’e-5 lunar soil 被引量:1
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作者 YunHong Fan BiWen Wang +3 位作者 Wei Yang QiuLi Li HuiJuan Zhang ShiTou Wu 《Earth and Planetary Physics》 2025年第6期1099-1112,共14页
Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical sign... Lunar impact glasses have been identified as crucial indicators of geochemical information regarding their source regions. Impact glasses can be categorized as either local or exotic. Those preserving geochemical signatures matching local lithologies (e.g., mare basalts or their single minerals) or regolith bulk soil compositions are classified as “local”. Otherwise, they could be defined as “exotic”. The analysis of exotic glasses provides the opportunity to explore previously unsampled lunar areas. This study focuses on the identification of exotic glasses within the Chang’e-5 (CE-5) soil sample by analyzing the trace elements of 28 impact glasses with distinct major element compositions in comparison with the CE-5 bulk soil. However, the results indicate that 18 of the analyzed glasses exhibit trace element compositions comparable to those of the local CE-5 materials. In particular, some of them could match the local single mineral component in major and trace elements, suggesting a local origin. Therefore, it is recommended that the investigation be expanded from using major elements to including nonvolatile trace elements, with a view to enhancing our understanding on the provenance of lunar impact glasses. To achieve a more accurate identification of exotic glasses within the CE-5 soil sample, a novel classification plot of Mg# versus La is proposed. The remaining 10 glasses, which exhibit diverse trace element variations, were identified as exotic. A comparative analysis of their chemical characteristics with remote sensing data indicates that they may have originated from the Aristarchus, Mairan, Sharp, or Pythagoras craters. This study elucidates the classification and possible provenance of exotic materials within the CE-5 soil sample, thereby providing constraints for the enhanced identification of local and exotic components at the CE-5 landing site. 展开更多
关键词 Chang’e-5 impact glass exotic materials classification PROVENANCE
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Three-Stage Transfer Learning with AlexNet50 for MRI Image Multi-Class Classification with Optimal Learning Rate
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作者 Suganya Athisayamani A.Robert Singh +1 位作者 Gyanendra Prasad Joshi Woong Cho 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期155-183,共29页
In radiology,magnetic resonance imaging(MRI)is an essential diagnostic tool that provides detailed images of a patient’s anatomical and physiological structures.MRI is particularly effective for detecting soft tissue... In radiology,magnetic resonance imaging(MRI)is an essential diagnostic tool that provides detailed images of a patient’s anatomical and physiological structures.MRI is particularly effective for detecting soft tissue anomalies.Traditionally,radiologists manually interpret these images,which can be labor-intensive and time-consuming due to the vast amount of data.To address this challenge,machine learning,and deep learning approaches can be utilized to improve the accuracy and efficiency of anomaly detection in MRI scans.This manuscript presents the use of the Deep AlexNet50 model for MRI classification with discriminative learning methods.There are three stages for learning;in the first stage,the whole dataset is used to learn the features.In the second stage,some layers of AlexNet50 are frozen with an augmented dataset,and in the third stage,AlexNet50 with an augmented dataset with the augmented dataset.This method used three publicly available MRI classification datasets:Harvard whole brain atlas(HWBA-dataset),the School of Biomedical Engineering of Southern Medical University(SMU-dataset),and The National Institute of Neuroscience and Hospitals brain MRI dataset(NINS-dataset)for analysis.Various hyperparameter optimizers like Adam,stochastic gradient descent(SGD),Root mean square propagation(RMS prop),Adamax,and AdamW have been used to compare the performance of the learning process.HWBA-dataset registers maximum classification performance.We evaluated the performance of the proposed classification model using several quantitative metrics,achieving an average accuracy of 98%. 展开更多
关键词 MRI TUMORS classification AlexNet50 transfer learning hyperparameter tuning OPTIMIZER
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Deep Learning and Artificial Intelligence-Driven Advanced Methods for Acute Lymphoblastic Leukemia Identification and Classification: A Systematic Review 被引量:1
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作者 Syed Ijaz Ur Rahman Naveed Abbas +5 位作者 Sikandar Ali Muhammad Salman Ahmed Alkhayat Jawad Khan Dildar Hussain Yeong Hyeon Gu 《Computer Modeling in Engineering & Sciences》 2025年第2期1199-1231,共33页
Automatic detection of Leukemia or blood cancer is one of the most challenging tasks that need to be addressed in the healthcare system.Analysis of white blood cells(WBCs)in the blood or bone marrow microscopic slide ... Automatic detection of Leukemia or blood cancer is one of the most challenging tasks that need to be addressed in the healthcare system.Analysis of white blood cells(WBCs)in the blood or bone marrow microscopic slide images play a crucial part in early identification to facilitate medical experts.For Acute Lymphocytic Leukemia(ALL),the most preferred part of the blood or marrow is to be analyzed by the experts before it spreads in the whole body and the condition becomes worse.The researchers have done a lot of work in this field,to demonstrate a comprehensive analysis few literature reviews have been published focusing on various artificial intelligence-based techniques like machine and deep learning detection of ALL.The systematic review has been done in this article under the PRISMA guidelines which presents the most recent advancements in this field.Different image segmentation techniques were broadly studied and categorized from various online databases like Google Scholar,Science Direct,and PubMed as image processing-based,traditional machine and deep learning-based,and advanced deep learning-based models were presented.Convolutional Neural Networks(CNN)based on traditional models and then the recent advancements in CNN used for the classification of ALL into its subtypes.A critical analysis of the existing methods is provided to offer clarity on the current state of the field.Finally,the paper concludes with insights and suggestions for future research,aiming to guide new researchers in the development of advanced automated systems for detecting life-threatening diseases. 展开更多
关键词 Acute lymphoblastic bone marrow SEGMENTATION classification machine learning deep learning convolutional neural network
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TMC-GCN: Encrypted Traffic Mapping Classification Method Based on Graph Convolutional Networks 被引量:1
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作者 Baoquan Liu Xi Chen +2 位作者 Qingjun Yuan Degang Li Chunxiang Gu 《Computers, Materials & Continua》 2025年第2期3179-3201,共23页
With the emphasis on user privacy and communication security, encrypted traffic has increased dramatically, which brings great challenges to traffic classification. The classification method of encrypted traffic based... With the emphasis on user privacy and communication security, encrypted traffic has increased dramatically, which brings great challenges to traffic classification. The classification method of encrypted traffic based on GNN can deal with encrypted traffic well. However, existing GNN-based approaches ignore the relationship between client or server packets. In this paper, we design a network traffic topology based on GCN, called Flow Mapping Graph (FMG). FMG establishes sequential edges between vertexes by the arrival order of packets and establishes jump-order edges between vertexes by connecting packets in different bursts with the same direction. It not only reflects the time characteristics of the packet but also strengthens the relationship between the client or server packets. According to FMG, a Traffic Mapping Classification model (TMC-GCN) is designed, which can automatically capture and learn the characteristics and structure information of the top vertex in FMG. The TMC-GCN model is used to classify the encrypted traffic. The encryption stream classification problem is transformed into a graph classification problem, which can effectively deal with data from different data sources and application scenarios. By comparing the performance of TMC-GCN with other classical models in four public datasets, including CICIOT2023, ISCXVPN2016, CICAAGM2017, and GraphDapp, the effectiveness of the FMG algorithm is verified. The experimental results show that the accuracy rate of the TMC-GCN model is 96.13%, the recall rate is 95.04%, and the F1 rate is 94.54%. 展开更多
关键词 Encrypted traffic classification deep learning graph neural networks multi-layer perceptron graph convolutional networks
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A novel method for clustering cellular data to improve classification
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作者 Diek W.Wheeler Giorgio A.Ascoli 《Neural Regeneration Research》 SCIE CAS 2025年第9期2697-2705,共9页
Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subse... Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are missing.We recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within clusters.Here we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical testing.These general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical datasets.We demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons. 展开更多
关键词 cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering
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Congruent Feature Selection Method to Improve the Efficacy of Machine Learning-Based Classification in Medical Image Processing
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作者 Mohd Anjum Naoufel Kraiem +2 位作者 Hong Min Ashit Kumar Dutta Yousef Ibrahim Daradkeh 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期357-384,共28页
Machine learning(ML)is increasingly applied for medical image processing with appropriate learning paradigms.These applications include analyzing images of various organs,such as the brain,lung,eye,etc.,to identify sp... Machine learning(ML)is increasingly applied for medical image processing with appropriate learning paradigms.These applications include analyzing images of various organs,such as the brain,lung,eye,etc.,to identify specific flaws/diseases for diagnosis.The primary concern of ML applications is the precise selection of flexible image features for pattern detection and region classification.Most of the extracted image features are irrelevant and lead to an increase in computation time.Therefore,this article uses an analytical learning paradigm to design a Congruent Feature Selection Method to select the most relevant image features.This process trains the learning paradigm using similarity and correlation-based features over different textural intensities and pixel distributions.The similarity between the pixels over the various distribution patterns with high indexes is recommended for disease diagnosis.Later,the correlation based on intensity and distribution is analyzed to improve the feature selection congruency.Therefore,the more congruent pixels are sorted in the descending order of the selection,which identifies better regions than the distribution.Now,the learning paradigm is trained using intensity and region-based similarity to maximize the chances of selection.Therefore,the probability of feature selection,regardless of the textures and medical image patterns,is improved.This process enhances the performance of ML applications for different medical image processing.The proposed method improves the accuracy,precision,and training rate by 13.19%,10.69%,and 11.06%,respectively,compared to other models for the selected dataset.The mean error and selection time is also reduced by 12.56%and 13.56%,respectively,compared to the same models and dataset. 展开更多
关键词 Computer vision feature selection machine learning region detection texture analysis image classification medical images
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