期刊文献+
共找到603篇文章
< 1 2 31 >
每页显示 20 50 100
Rainwater quality assessment of a solidified soil cistern using new construction technology
1
作者 许秀泉 高建恩 《Journal of Southeast University(English Edition)》 EI CAS 2014年第2期240-245,共6页
A plastic mixture construction technology using MBER (material becoming earth into rock) soil stabilizer is introduced and the water quality of a solidified soil cistern using the technology is analyzed. Rainwater w... A plastic mixture construction technology using MBER (material becoming earth into rock) soil stabilizer is introduced and the water quality of a solidified soil cistern using the technology is analyzed. Rainwater was harvested in July, 2012. Water quality of runoff and cistern water after storage was measured, including turbidity, chemical oxygen demand (COD), total nitrogen, nitrate, and ammonia. Results show that pollutant concentrations in runoff decreased with time, indicating that runoff in the early time should be removed. Nitrate concentrations in cistern water increased after storage, while the remaining parameters decreased. Measured pollutant concentrations did not exceed the limit according to the standard for drinking water in China. It can be concluded that the solidified soil cistern with plastic mixture construction technology can provide available water for domestic use. 展开更多
关键词 soil stabilizer cistern construction technology water quality
在线阅读 下载PDF
Interpeduncular cistern intrathecal targeted drug delivery for intractable postherpetic neuralgia: A case report 被引量:4
2
作者 Feng Fu Xian-Feng Jiang +4 位作者 Jing-Jing Wang Lei Gong Chen Yun Hong-Tao Sun Feng-Wu Tang 《World Journal of Clinical Cases》 SCIE 2023年第30期7380-7385,共6页
BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may ben... BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may benefit from an intrathecal drug delivery system(IDDS).For craniofacial neuropathic pain,the traditional approach has been to place the intrathecal catheter tip below the level of the cranial nerve root entry zones,which may lead to insufficient analgesia.CASE SUMMARY We describe a 69-year-old man with a 1-year history of PHN after developing a vesicular rash in the ophthalmic division of cranial nerve V(trigeminal nerve)distribution.The pain was rated 7-8 at rest and 9-10 at breakthrough pain(BTP)on a numeric rating scale.Despite receiving aggressive multimodal therapies including large doses of oral analgesics(gabapentin 150 mg q12 h,oxycodone 5 mg/acetaminophen 325 mg q6 h,and lidocaine 5%patch 700 mg q12 h)and sphenopalatine ganglion block,there was no relief of pain.Subsequently,the patient elected to have an implantable IDDS with the catheter tip placed at the interpeduncular cistern.The frequency of BTP episodes decreased.The patient’s continuous daily dose was adjusted to 0.032 mg/d after 3 mo of follow-up and stopped 5 mo later.He did not report pain or other discomfort at outpatient follow-up 6 mo and 1 year after stopping intracisternal hydromorphone.CONCLUSION The use of interpeduncular cistern intrathecal infusion with low-dose hydromorphone by IDDS may be effective for severe craniofacial PHN. 展开更多
关键词 Postherpetic neuralgia Intrathecal drug delivery Interpeduncular cistern Craniofacial pain OPIOIDS Case report
暂未订购
Suprasellar cistern tuberculoma presenting as unilateral ocular motility disorder and ptosis:A case report
3
作者 Bi-Bo Zhao Chao Tian +1 位作者 Le-Jun Fu Xue-Bin Zhang 《World Journal of Clinical Cases》 SCIE 2022年第14期4691-4697,共7页
BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberc... BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection. 展开更多
关键词 Tuberculosis Intracranial tuberculoma Suprasellar cistern Ocular motility disorder PTOSIS Case report
暂未订购
Hormonal (Thyroxin, Cortisol) and Immunological (Leucocytes) Responses to Cistern Size and Heat Stress in Tunisia
4
作者 Rim Ben Younes Moez Ayadi +3 位作者 Taha Najar Margherita Caccamo Iris Schadt Moncef Ben M'Rad 《Journal of Life Sciences》 2011年第5期332-338,共7页
This study was designed to determine the effects of heat stress on plasma leucocytes, Thyroxin (T4) and cortisol concentrations in dairy cows with small and large cistern under hot climate. This experiment was carri... This study was designed to determine the effects of heat stress on plasma leucocytes, Thyroxin (T4) and cortisol concentrations in dairy cows with small and large cistern under hot climate. This experiment was carried out in 2006, in North Tunisia, using a randomized block design per udder cistern size, using 60 Holstein cows. Cows were classified according to udder cistern size by ultrasonography as large-cisterned (44 ±13 cm2; LC) and small-cisterned (21 ± 8 cm2; SC). The experiment was carried out in two different periods: spring (Apr. 5 (D1)) and summer (July 19 (D2), Aug. 19 (D3) and Sept. 19 (D4)). On each test day, temperature and relative humidity data were registered hourly and cows' blood was sampled from the jugular vein to determine serum concentrates of cortisol and T4. Leucocytes (lyrnphocytes, eosinophils, neutrophils and monocytes) were counted differentially, and percentages of lymphocytes relative to total counted cells were calculated. Mean temperature-humidity index (THI) values were 62 ±2, 79 ±2, 84 ±2, and 77 ±1 in DI, D2, D3, and D4, respectively. Lymphocyte incidence relative to total cell counts and T4 concentrations were affected by test day (P 〈 0.001). Lymphocytes (%) were significantly less in hotter months. During summer, T4 concentration at D2 (87.4 nmol/L) was higher relative to concentrations at D3 (42.8 nmol/L) and D4 (53.5 nmol/L). T4 concentrations were higher (P 〈 0.01) in SC cows (67.7 ±0.1 nmol/L) compared to LC cows (52.7 ±0.1 nmol/L). Cortisol concentration was effected neither by test day nor by cistern size. However, the decrease of lymphocyte concentration during summer compared to spring could be considered as an evidence of the suppression of cows' immune system under heat stress. 展开更多
关键词 Heat stress cistern size CORTISOL THYROXIN lymphocytes.
在线阅读 下载PDF
The Development and Application of CISMOD 1.0, a New Computerized Tool for Designing Wildlife Rainwater Cisterns
5
作者 Ariel Ortega Dave Menicucci 《Computational Water, Energy, and Environmental Engineering》 2021年第2期71-81,共11页
This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in ... This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in locations that do not have natural water sources, such as streams or wells that can supply water for storage. However, the design and sizing of such a system can be challenging because a number of constantly varying factors must be considered, such as changing precipitation patterns, the evaporative losses from the cistern and </span><span style="font-family:Verdana;">animal water consumption. No standardized sizing methodology currently</span><span style="font-family:Verdana;"> exists for designing wildlife rainwater cisterns. In this article we present a new method for assisting in optimally sizing a rainwater cistern. We discuss how we implemented the quantitative portion of this methodology into a new Excel? model called CISMOD, which we configured for general use by wildlife professionals. We describe the methodology for designing a rainwater cistern based on standard engineering techniques. We then present and discuss our experience in applying the model to design two rainwater cisterns in an area of the Jemez Mountains in northern New Mexico, USA. The CISMOD model and a user manual are available at no cost for wildlife professionals. 展开更多
关键词 cistern WILDLIFE Design SIZING Construction
在线阅读 下载PDF
Suitability and Sustainability of Rainwater QualityMonitoring System in Cistern for Domestic Use
6
作者 Kenedy A.Greyson 《Journal on Internet of Things》 2023年第1期1-11,共11页
Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources ... Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources of contamination in the rainwater cistern systems.Dissolved chemicals from the roofing,storage,and conveyance materials,together with the suspended particulate matter from the airborne,are examples of water contamination.In this work,the water quality monitoring system has been designed and implemented.Chemical and physical parameters of water samples were collected from three locations using a data acquisition(DAQ)system and rainwater quality was analyzed using Water Pollution Index(WPI).Results obtained from three locations have been presented. 展开更多
关键词 cistern DAQ system monitoring system RWH system water pollution WPI
在线阅读 下载PDF
Discussion on the Curative Effect of Lumbar Cistern - Abdominal Shunt in the Treatment of Traffic Hydrocephalus
7
作者 DU Feixiong 《外文科技期刊数据库(文摘版)医药卫生》 2021年第8期401-403,共5页
Objective: to analyze the patients with communicating hydrocephalus as a whole, and then perform lumbar cistern abdominal shunt, or LPS for short, and on this basis, to carry out the diagnosis and treatment and summar... Objective: to analyze the patients with communicating hydrocephalus as a whole, and then perform lumbar cistern abdominal shunt, or LPS for short, and on this basis, to carry out the diagnosis and treatment and summarize the clinical diagnosis and treatment results. Methods: from November 2019 to November 2020, 37 patients with communicating hydrocephalus received in the hospital were randomly selected for lumbar cistern abdominal shunt. Results: of the 37 patients, 30 needed pressure regulation immediately after the operation, and the maximum number of times of pressure regulation was four. After surgical treatment, the overall symptoms of the patients showed signs of improvement, among which 22 patients' conditions were significantly relieved. After the operation, the head CT examination was performed on the patients. The enlarged ventricles of the brain eventually showed significant reduction, and the interstitial edema was relieved. Among them, 25 patients recovered and returned to normal values. After the operation, there was one patient with infection, and the patient gradually recovered after antibiotic treatment. Of these 37 patients, 18 had excessive shunting and 12 had insufficient shunting, all of which improved after pressure adjustment. Conclusion: for patients with communicating hydrocephalus, lumbar cistern abdominal shunt is effective. 展开更多
关键词 lumbar cistern abdominal shunt traffic hydrocephalus treatment effect
暂未订购
Microsurgical anatomy of the ambient cistern and its related arachnoidal membranes
8
作者 樊俊 《外科研究与新技术》 2011年第3期228-228,共1页
Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membra... Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membranes were observed in 20 cadaveric brains using an operating microscope. Results The 展开更多
关键词 Microsurgical anatomy of the ambient cistern and its related arachnoidal membranes
暂未订购
Cisternal and intraventricular irrigation in subarachnoid and intraventricular haemorrhage
9
作者 Allice Nyborg Rosenkrans Lind Mathias Green Krabbenhøft +5 位作者 Jan Brink Valentin Mette Haldrup Stig Dyrskog Mads Rasmussen Claus Ziegler Simonsen Anders Rosendal Korshoej 《Stroke & Vascular Neurology》 2025年第1期5-15,共11页
Background Subarachnoid haemorrhage(SAH)and intraventricular haemorrhage(IVH)are associated with poor patient outcomes.Intraventricular fibrinolysis is effective in clearing IVH and improving patient survival and neur... Background Subarachnoid haemorrhage(SAH)and intraventricular haemorrhage(IVH)are associated with poor patient outcomes.Intraventricular fibrinolysis is effective in clearing IVH and improving patient survival and neurological outcome.By similar rationale,cisternal irrigation has been proposed as a potential method to accelerate haematoma clearance in SAH.We aimed to provide a comprehensive review and meta-analysis evaluating the effect of intraventricular and cisternal irrigation on clinical outcomes in patients with SAH and IVH.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed preparing this systematic review and study selection was performed by multiple investigators.We extracted ORs from the individual studies and aggregated these using a random effects model.The quality of evidence was evaluated using Grading of Recommendations,Assessment,Development and Evaluations assessment and ROBINS-I or RoB-2.Results 24 articles were included.In SAH,we found that cisternal irrigation with fibrinolytic agents was associated with reduced mortality(OR:0.68,95%CI 0.46 to 1.00),higher probability of favourable functional outcome(OR:1.80,95%CI 1.30 to 2.51),and reduced risks of DCI(OR:0.28,95%CI 0.18 to 0.42)and cerebral vasospasm(OR:0.28,95%CI 0.18 to 0.42),compared with conventional therapy.Cisternal irrigation with vasodilatory agents was associated with lower mortality(OR:0.32,95%CI 0.13 to 0.79)and reduced risk of cerebral vasospasm(OR:0.37,95%CI 0.17 to 0.79).The evidence for irrigation therapy of IVH was sparse and insufficient to show any significant effect.Conclusion In this study,we found that cisternal irrigation could improve the prognosis in patients with SAH compared with conventional therapy.There is no evidence to support cisternal irrigation treatment of IVH. 展开更多
关键词 cisternal Irrigation accelerate haematoma clearance Clinical Outcomes subarachnoid haemorrhage sah Intraventricular Fibrinolysis Subarachnoid Hemorrhage intraventricular haemorrhage ivh intraventricular cisternal irrigation
原文传递
重型颅脑损伤患者去骨瓣减压术后脑池造瘘引流与硬膜下引流对患者颅内压及预后转归的影响
10
作者 邵双伟 李帆 +2 位作者 李建红 王伟 杨涛 《中华保健医学杂志》 2025年第4期630-634,共5页
目的分析重型颅脑损伤(severe traumatic brain injury,sTBI)患者去骨瓣减压术后脑池造瘘引流与硬膜下引流对颅内压及预后转归的影响。方法选取2022年1月~2023年12月长治医学院附属和济医院收治的82例sTBI患者为研究对象,均行去骨瓣减压... 目的分析重型颅脑损伤(severe traumatic brain injury,sTBI)患者去骨瓣减压术后脑池造瘘引流与硬膜下引流对颅内压及预后转归的影响。方法选取2022年1月~2023年12月长治医学院附属和济医院收治的82例sTBI患者为研究对象,均行去骨瓣减压术,依据随机数字表法将患者分为A组(脑池造瘘引流,41例)、B组(硬膜下引流,41例)。记录两组患者术后机械通气时间、住院时间及感染率,并对比术后不同时间点颅内压,术后1、3、5、7和14 d的格拉斯哥昏迷评分(GCS),以及术前、术后血乳酸水平、鹿特丹CT评分系统(Rotterdam CT)、脑卒中改良Rankin量表(mRS)评分。结果两组患者术后机械通气时间、住院时间及颅内感染率比较,差异均无统计学意义(P>0.05)。A组术后6、12、24、48和72 h颅内压均低于B组,差异有统计学意义(P<0.05)。术前,两组血乳酸水平比较无统计学意义(P>0.05),术后24、72 h血乳酸水平较术前均下降,且A组低于B组,差异有统计学意义(P<0.05)。两组术前及术后1、3 d的GCS评分对比无显著差异(P>0.05),A组术后5、7、14 d GCS评分均显著高于B组,差异有统计学意义(P<0.05)。两组术前Rotterdam CT评分比较无显著差异(P>0.05),两组术后48 h Rotterdam CT评分较术前均下降,且A组较B组更低,差异有统计学意义(P<0.05)。两组术前mRS评分比较无统计学意义(P>0.05),两组术后3个月mRS评分较术前均下降,且A组较B组更低,差异有统计学意义(P<0.05)。结论相较于硬膜下引流,sTBI患者去骨瓣减压术后应用脑池造瘘引流,在降低患者颅内压及改善预后方面优势更为明显。 展开更多
关键词 重型颅脑损伤 脑池造瘘引流 硬膜下引流 颅内压 预后转归 去骨瓣减压术
暂未订购
脑体积和脑池积血量在动脉瘤性蛛网膜下腔出血预后评估中的价值
11
作者 翟艳 梁慧青 +3 位作者 王亚新 葛敏 马非凡 甘宁 《中国临床神经外科杂志》 2025年第6期326-332,共7页
目的 探讨脑体积和脑池积血量对动脉瘤性蛛网膜下腔出血(aSAH)患者预后的评估价值。方法 回顾性分析2019年1月至2021年1月收治的160例aSAH患者的临床资料。根据入院后1周动态CT影像,使用3D Slicer软件测量脑体积和脑池积血量,计算脑体... 目的 探讨脑体积和脑池积血量对动脉瘤性蛛网膜下腔出血(aSAH)患者预后的评估价值。方法 回顾性分析2019年1月至2021年1月收治的160例aSAH患者的临床资料。根据入院后1周动态CT影像,使用3D Slicer软件测量脑体积和脑池积血量,计算脑体积变化率=(脑体积最大值-脑体积最小值)/颅腔体积×100%。末次随访,根据GOS评分评估预后,其中4~5分为预后良好,1~3分为预后不良。采用多因素logistic回归模型分析预后影响因素。ROC曲线分析脑体积和脑池积血量评估aSAH患者预后的价值。结果 所有患者随访9~24个月,中位数14.6个月。160例中,预后良好98例,预后不良62例。多因素logistic回归分析表明,脑体积变化率大(OR=3.456;95%CI 1.359~8.784;P=0.009)、脚间池积血(OR=2.622;95%CI 1.240~5.544;P=0.012)是aSAH患者预后不良的独立危险因素。ROC曲线分析显示,脑体积变化率、脚间池积血预测aSAH患者预后不良的的曲线下面积分别为0.784(95%CI 0.711~0.857)、0.712(95%CI 0.631~0.792)、敏感度分别为77.42%、66.13%,特异度分别为71.43%、60.20%。结论 入院后1周脑体积变化率和脚间池积血量对aSAH患者预后具有一定的评估价值。 展开更多
关键词 动脉瘤性蛛网膜下腔出血 脑体积 脑池积血量 预后评估
暂未订购
尼莫地平联合持续腰大池引流防治动脉瘤性蛛网膜下腔出血术后脑血管痉挛的效果
12
作者 杨正刚 《临床合理用药》 2025年第9期18-21,26,共5页
目的观察尼莫地平联合持续腰大池引流防治动脉瘤性蛛网膜下腔出血术后脑血管痉挛的效果。方法回顾性选取2021年8月—2023年8月松滋市人民医院收治的动脉瘤性蛛网膜下腔出血患者68例,根据治疗用药方案不同分为试验组和对照组,每组34例。... 目的观察尼莫地平联合持续腰大池引流防治动脉瘤性蛛网膜下腔出血术后脑血管痉挛的效果。方法回顾性选取2021年8月—2023年8月松滋市人民医院收治的动脉瘤性蛛网膜下腔出血患者68例,根据治疗用药方案不同分为试验组和对照组,每组34例。在常规治疗+持续腰大池引流基础上,试验组应用尼莫地平注射液治疗,对照组应用盐酸维拉帕米注射液治疗,2组均用药治疗1周。比较2组临床疗效,治疗1、2周后脑血管痉挛程度,治疗前与治疗2周后脑血流动力学指标、血清学指标。结果试验组治疗总有效率高于对照组(97.06%vs.76.47%,χ^(2)=4.610,P=0.032)。治疗1周后,2组无痉挛、轻度痉挛、重度痉挛患者占比比较,差异无统计学意义(P>0.05),试验组中度痉挛患者占比低于对照组(14.71%vs.38.24%,χ^(2)=4.836,P=0.028);治疗2周后,试验组无痉挛患者占比高于对照组(55.88%vs.26.47%,χ^(2)=6.071,P=0.014),中度痉挛患者占比低于对照组(0 vs.20.59%,χ^(2)=5.733,P=0.017),2组轻度痉挛、重度痉挛患者占比比较,差异无统计学意义(P>0.05)。治疗2周后,2组脑血容量、脑血流量较治疗前增加,对比剂达峰时间、对比剂平均通过时间较治疗前缩短,且试验组增加/缩短幅度大于对照组(P<0.01);2组血清基质金属蛋白酶-9、S-100钙结合蛋白B、可溶性细胞间黏附分子-1及可溶性血管细胞黏附分子-1水平较治疗前下降,且试验组低于对照组(P<0.01)。结论相较于维拉帕米,尼莫地平联合持续腰大池引流防治动脉瘤性蛛网膜下腔出血术后脑血管痉挛的效果更为显著,可减轻患者脑血管痉挛程度,改善脑部血液循环,避免脑损伤加重。 展开更多
关键词 动脉瘤性蛛网膜下腔出血 脑血管痉挛 尼莫地平 手术治疗 持续腰大池引流
原文传递
头颅CT环池分级、D-二聚体及格拉斯哥昏迷量表评分对重型颅脑损伤患者术后近期预后的预测价值 被引量:2
13
作者 张列祥 何裕超 +6 位作者 蔡畅 付宪华 李猛 徐进 姜宁 王协锋 陈宏璘 《实用临床医药杂志》 2025年第8期17-21,共5页
目的探讨头颅CT环池分级联合D-二聚体(D-D)、格拉斯哥昏迷量表(GCS)评分预测重型颅脑损伤患者术后近期预后的价值。方法选取2019年1月—2024年5月在医院治疗的重型颅脑损伤患者165例为研究对象,均行开颅手术治疗。术后随访3个月,分析预... 目的探讨头颅CT环池分级联合D-二聚体(D-D)、格拉斯哥昏迷量表(GCS)评分预测重型颅脑损伤患者术后近期预后的价值。方法选取2019年1月—2024年5月在医院治疗的重型颅脑损伤患者165例为研究对象,均行开颅手术治疗。术后随访3个月,分析预后不良和预后良好患者临床资料及术前头颅CT环池分级、D-D水平、GCS评分等指标的差异,并分析头颅CT环池分级、D-D水平、GCS评分在预测重型颅脑损伤患者术后近期预后不良的价值。结果与预后良好患者比较,预后不良患者年龄、头颅CT环池分级Ⅰ~Ⅱ级,D-D水平和GCS评分<6分占比较高,差异有统计学意义(P<0.05);预后不良和预后良好患者C反应蛋白、凝血酶原时间、活化部分凝血活酶时间、国际标准化比率、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇水平比较,差异无统计学意义(P>0.05)。头颅CT环池分级、D-D水平、GCS评分是重型颅脑损伤患者术后近期预后不良的影响因素(P<0.05)。三者联合预测预后不良的曲线下面积为0.941(95%CI:0.906~0.975),高于头颅CT环池分级、D-D水平和GCS评分单独预测的曲线下面积。结论重型颅脑损伤患者术后近期预后的影响因素包括头颅CT环池分级、D-D水平、GCS评分,基于三者构建的模型在预测患者预后方面具有一定应用价值。 展开更多
关键词 头颅 CT环池分级 D-二聚体 预测 格拉斯哥昏迷量表 重型颅脑损伤 近期预后 影响因素
暂未订购
经腰椎入路脑桥前池吗啡泵治疗难治性头颈部癌痛的疗效
14
作者 张文婕 尹柏华 +4 位作者 李欣宁 雷嘉昕 肖艳英 王亚平 邹定全 《中南大学学报(医学版)》 北大核心 2025年第6期995-1001,共7页
目的:头颈部难治性癌痛患者的疼痛管理是目前临床上较为棘手的问题之一,传统鞘内给药模式镇痛作用欠佳,尚未有完善且有效的治疗手段。本研究旨在观察经腰椎入路脑桥前池吗啡泵治疗难治性头颈部癌痛的疗效及安全性。方法:选取2019年9月至... 目的:头颈部难治性癌痛患者的疼痛管理是目前临床上较为棘手的问题之一,传统鞘内给药模式镇痛作用欠佳,尚未有完善且有效的治疗手段。本研究旨在观察经腰椎入路脑桥前池吗啡泵治疗难治性头颈部癌痛的疗效及安全性。方法:选取2019年9月至2023年7月中南大学湘雅二医院疼痛科收治的18例采用脑桥前池吗啡泵治疗难治性头颈部癌痛的患者为研究对象。分别于术前,术后1周、1个月、2个月收集患者疼痛数字分级评分法(Numerical Rating Scale,NRS)和抑郁自评量表(Self-rating Depression Scale,SDS)评分、日口服吗啡剂量、日暴发痛次数及术后日鞘内吗啡剂量等指标。结果:术后患者各时间点的NRS、SDS评分及日口服吗啡剂量、日暴发痛次数均较术前明显降低(均P<0.05)。随着术后日鞘内吗啡剂量的缓慢增加,患者术后各时间段的日口服吗啡剂量均较术前显著减少(均P<0.05)。手术相关并发症轻微,其中恶心5例(31.3%)、头痛2例(12.5%),低血压、尿潴留、嗜睡、便秘各1例(各6.3%),未发生严重不良事件,患者通过对症治疗后均好转出院。结论:脑桥前池吗啡泵置入术可有效控制难治性头颈部癌痛,在规范操作的前提下,具有微创、不良反应轻、用药量少的特点。 展开更多
关键词 脑桥前池 吗啡泵 难治性癌痛 头颈癌 鞘内靶向药物输注
暂未订购
经皮小脑延髓池穿刺重复抽取大鼠脑脊液的方法研究
15
作者 姚路路 李傅尧 +4 位作者 倪敬年 魏明清 李婷 时晶 田金洲 《神经损伤与功能重建》 2025年第3期125-129,共5页
目的:提出一种操作简便、重复性高的方法,可用于重复采集大鼠脑脊液(cerebrospinal fluid,CSF)样本。方法:25只SD大鼠随机分为对照组和实验组。实验组大鼠麻醉后,调整其头部相对于身体呈45°~90°,以枕骨隆突和第一颈椎之间的... 目的:提出一种操作简便、重复性高的方法,可用于重复采集大鼠脑脊液(cerebrospinal fluid,CSF)样本。方法:25只SD大鼠随机分为对照组和实验组。实验组大鼠麻醉后,调整其头部相对于身体呈45°~90°,以枕骨隆突和第一颈椎之间的中心位置为进针点,针尖向头侧,平行于大鼠头部弯曲方向缓慢刺入,进针深度约为5 mm。缓慢抽吸CSF并记录采样量。通过观察大鼠体重变化和Bederson评分,伊文思蓝和HE染色,检测CSF白细胞介素-6(interleukin-6,IL-6)进行综合评估。结果:实验组大鼠首次采样成功14只(70.0%),采样量为(93.30±13.33)μL。连续二次采样成功10只(50.0%),第二次采样量为(93.00±19.86)μL。连续三次采样成功8只(40.0%),第三次采样量为(89.75±7.72)μL。连续三次采样成功组的大鼠体重增加(47.6±1.51)g,与对照组相比差异无统计学意义(P>0.05)。实验组大鼠Bederson评分均为0分,提示未造成明显神经功能缺损。未观察到明显的伊文思蓝染色和脑组织形态学改变。三次采集的CSF样本中IL-6含量分别为(28.98±4.70)pg/mL、(29.37±6.06)pg/mL和(30.06±5.47)pg/mL,三次对比差异无统计学意义(P>0.05)。第一次采样失败后再次采样成功的CSF样本IL-6含量升高(P<0.05)。结论:经皮小脑延髓池穿刺抽取CSF的方法所需器材简单,操作时间短,可单人操作,且对动物创伤小。 展开更多
关键词 经皮穿刺 小脑延髓池 脑脊液 方法研究
暂未订购
高血压脑出血患者神经内镜颅内血肿清除术后大脑环池受压和形态分级与预后的关系
16
作者 李瑞 何绍坤 +5 位作者 杨云川 高锋 孙碧文 何世维 朱云飞 肖文峰 《中国内镜杂志》 2025年第9期17-28,共12页
目的 探究高血压脑出血(HCH)患者神经内镜颅内血肿清除术(NEIHE)后大脑环池受压程度和形态分级与预后的关系。方法 选择2020年1月-2023年6月于该院接受NEIHE治疗的HCH患者246例。根据术后6个月格拉斯哥预后评分(GOS),将患者分为预后良好... 目的 探究高血压脑出血(HCH)患者神经内镜颅内血肿清除术(NEIHE)后大脑环池受压程度和形态分级与预后的关系。方法 选择2020年1月-2023年6月于该院接受NEIHE治疗的HCH患者246例。根据术后6个月格拉斯哥预后评分(GOS),将患者分为预后良好组(n=158)和预后不良组(n=88)。采用分层回归模型,分析临床病理特征与大脑环池受压程度和形态分级的关系。采用多因素Logistic回归模型,分析影响HCH患者NEIHE后预后不良的独立危险因素,并构建预测模型。以预后不良为结局变量,绘制受试者操作特征曲线(ROC curve)。比较不同预测模型的曲线下面积(AUC)、综合判别改善指数(IDI)和净重新分类指数(NRI)。采用Hosmer-Lemeshow拟合优度检验判断模型的拟合优度。采用广义相加模型(GAM),分析GOS与相关影响因素的关系。结果 与预后良好组相比,预后不良组术前出血量更多,术前格拉斯哥昏迷评分(GCS)更低,中线偏移、高血压病史≥10年、出血破入脑室、手术时机在晚期的患者占比更高,差异均有统计学意义(P<0.05)。与预后良好组相比,预后不良组血肿同侧及对侧大脑环池受压3至4分和大脑环池形态分级为Ⅴ级的患者占比更高,差异均有统计学意义(P<0.05)。分层回归分析显示,出血部位、中线偏移和颅内压对大脑环池受压程度及形态分级有影响,差异均有统计学意义(P<0.05)。多因素Logistic回归分析(模型2:包含大脑环池受压程度和形态分级)结果显示,中线偏移、高血压病史≥10年、术前出血量> 37 mL、出血破入脑室、术前GCS<7分、手术时机晚期、大脑环池受压程度(血肿同侧3至4分,血肿对侧3至4分)和形态分级Ⅴ级,是影响HCH患者NEIHE后预后不良的独立危险因素(P<0.05)。模型1(不包含大脑环池受压程度和形态分级)加入大脑环池受压程度和形态分级后,AUC提高到0.812(95%CI:0.763~0.872),且模型的IDI(0.081,95%CI:0.049~0.095)和NRI(0.611,95%CI:0.510~0.674)提高,差异均有统计学意义(P<0.05)。与模型1比较,模型2的AUC(0.826,95%CI:0.771~0.863)、IDI(0.085,95%CI:0.052~0.110)和NRI(0.628,95%CI:0.510~0.709)提高,差异均有统计学意义(P<0.05)。Hosmer-Lemeshow检验显示,预后不良预测模型2(P=0.878)较模型1(P=0.691)的拟合优度更理想。GAM分析显示,大脑环池受压程度越严重和形态分级越高,GOS评分越低,差异有统计学意义(P<0.05)。ROC curve分析显示,大脑环池受压程度和形态分级联合应用,对预后不良的预测价值较高,AUC为0.935(95%CI:0.890~0.971),敏感度为70.26%,特异度为93.84%。结论 HCH患者NEIHE后大脑环池受压程度和形态改变与预后密切相关,且联合应用对预后不良具有一定的预测价值。出血部位、中线偏移和颅内压等因素,明显影响大脑环池受压程度和形态改变。 展开更多
关键词 颅内出血 高血压 神经内镜 环池形态 预后
暂未订购
The prospective study of the relationship between perimesencephalic cistern of CT scanning and the outcome of the patients with acute craniocerebral injury 被引量:2
17
作者 龙连圣 江基尧 《Chinese Journal of Traumatology》 CAS 2003年第4期226-228,共3页
Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebra... Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebral injury.Methods: The CT scan features including the states of perimesencephalic cisterns, the deformations of the midbrain and the ratios of the occipitofrontal diameter and the transverse diameter of the midbrain of 132 cases were measured. The GOS of the patients 3 months after trauma were regarded as outcome.Results: The rate of unfavorable outcome ( dead, vegetative status, severe disability ) was significantly correlated with perimesencephalic cistern narrower than 1mm (P < 0.05), especially narrower than 0.5 mm (P < 0.005), deformed midbrain (P< 0.005) or abnormal ratio ( < 0.9 or >.1) of the occipitofrontal diameter and transverse diameter of the midbrain (P < 0.01). But the patient's perimesencephalic cistern wider than 1mm and the patients without deformed midbrain got favorable outcome (moderate disability/good recovery).Conclusions: The state of the compressedperimesencephalic cistern ( < 1 mm) and the deformation of the midbrain may significantly indicate unfavorable outcome of the patients with acute craniocerebral injury. 展开更多
关键词 Perimesencephalic cistern CT scanning OUTCOME Acute craniocerebral injury
原文传递
Chiari畸形Ⅰ型患者术后常规腰大池置管引流术的临床疗效
18
作者 樊宇耕 袁胤淞 +2 位作者 赵开胜 杨小岗 强京灵 《延安大学学报(医学科学版)》 2025年第1期32-36,共5页
目的观察常规行腰大池置管引流术(lumbar continuous drainage of fluid,LCDF)对Chiari畸形Ⅰ型患者术后早期并发症的临床疗效。方法回顾性分析2019年07月至2022年12月收治的Chiari畸形Ⅰ型68例患者的临床资料,均在全麻下行后正中入路... 目的观察常规行腰大池置管引流术(lumbar continuous drainage of fluid,LCDF)对Chiari畸形Ⅰ型患者术后早期并发症的临床疗效。方法回顾性分析2019年07月至2022年12月收治的Chiari畸形Ⅰ型68例患者的临床资料,均在全麻下行后正中入路软膜下下疝小脑扁桃体切除及枕大池重建术。按照术后第1天是否行LCDF分为两组,观察组36例行LCDF,对照组32例未行LCDF,比较分析两组患者术后临床症状恢复时间、术后并发症及术后住院时间,术后随访12个月,观察两组的远期疗效情况。结果两组术后随访无死亡病例,对照组总并发症发生率为71.88%,观察组总并发症发生率为25.0%,观察组并发症发生率低于对照组;对照组平均术后住院时间(14.8±1.8)d,观察组平均术后住院时间(10.4±1.5)d,观察组术后住院时长较对照组更短,两组之间差异具有统计学上的显著性意义。两组术后临床症状恢复时间、术后远期疗效情况比较差异无统计学意义(P>0.05)。结论Chiari畸形I型患者实施后正中入路小脑扁桃体软膜下下疝切除联合枕大池重建术后常规行LCDF可明显降低术后并发症,缩短术后住院时间,减少住院费用,符合术后加速康复理念。 展开更多
关键词 Chiari畸形Ⅰ型 小脑扁桃体切除 腰大池引流 枕大池重建。
暂未订购
泡沫敷料联合“回”字型胶布固定腰大池引流管三通阀的效果
19
作者 胡璀 徐园华 方文超 《浙江临床医学》 2025年第1期136-137,共2页
目的 观察自黏性软聚硅酮有边型泡沫敷料联合“回”字型3M胶布固定腰大池引流管三通阀的效果。方法 将59例行腰大池引流患者分成2组,其中观察组30例采用自黏性软聚硅酮有边型泡沫敷料联合“回”字型3M胶布固定,对照组29例采用普通胶布... 目的 观察自黏性软聚硅酮有边型泡沫敷料联合“回”字型3M胶布固定腰大池引流管三通阀的效果。方法 将59例行腰大池引流患者分成2组,其中观察组30例采用自黏性软聚硅酮有边型泡沫敷料联合“回”字型3M胶布固定,对照组29例采用普通胶布二道固定,比较两组患者留置腰大池引流管期间非计划性拔管、皮肤过敏反应、敷料更换次数及并发症发生情况。结果 观察组皮肤异常1例,敷料异常3例;对照组皮肤异常1例,敷料异常9例,两组比较差异有统计学意义(P<0.05)。结论 自黏性软聚硅酮有边型泡沫敷料联合“回”字型3M胶布固定腰大池引流管三通阀的应用显著减少了腰大池引流管敷料更换的频率,减少皮肤损伤的发生,增加管路固定的有效性,具有临床推广应用的价值。 展开更多
关键词 腰大池引流 固定方法 护理 泡沫敷料
暂未订购
腰大池、双侧脑室引流加尿激酶脑室注射治疗脑室出血患者的临床效果
20
作者 郭宏伟 扈俊华 +2 位作者 聂乾坤 马陈建 杨明涛 《河南医学研究》 2025年第16期3009-3012,共4页
目的探讨腰大池引流联合双侧脑室引流及尿激酶脑室注射治疗脑室出血(IVH)患者的临床效果。方法回顾性分析2020年1月至2025年1月收治的96例Graeb评分≥6分的IVH患者,分为对照组(双侧脑室引流+尿激酶注射,45例)和试验组(在对照组治疗基础... 目的探讨腰大池引流联合双侧脑室引流及尿激酶脑室注射治疗脑室出血(IVH)患者的临床效果。方法回顾性分析2020年1月至2025年1月收治的96例Graeb评分≥6分的IVH患者,分为对照组(双侧脑室引流+尿激酶注射,45例)和试验组(在对照组治疗基础上联合腰大池引流,51例)。比较两组血肿清除率、脑脊液循环恢复时间、引流管留置时间、住院时间、并发症发生率及格拉斯哥预后量表(GOS)评分。结果试验组术后3 d和5 d血肿清除率均高于对照组(P<0.001);脑脊液循环恢复时间及住院时间均低于对照组(P<0.001)。试验组颅内感染、脑积水和总并发症发生率降低(P=0.046),术后6个月恢复良好率更高(P=0.025)。结论腰大池引流联合双侧脑室引流及尿激酶注射可加速血肿清除、减少并发症并改善预后,是治疗中重度IVH的安全有效方案。 展开更多
关键词 脑室出血 腰大池引流 脑室引流 尿激酶 预后
暂未订购
上一页 1 2 31 下一页 到第
使用帮助 返回顶部