Based on the Chen chaotic system, a new four-dimensional hyperchaotic Chen system is constructed, and the basic dynamic behaviours of the system were studied, and the generalized synchronization has been observed in t...Based on the Chen chaotic system, a new four-dimensional hyperchaotic Chen system is constructed, and the basic dynamic behaviours of the system were studied, and the generalized synchronization has been observed in the coupled four-dimensional hyperchaotic Chen system with unknown parameters. The Routh Hurwitz theorem is used to derive the conditions of stability of this system. Furthermore based on Lyapunov stability theory, the control laws and adaptive laws of parameters are obtained to make generalized synchronization of the coupled new four-dimensional hyperchaotic Chen systems. Numerical simulation results are presented to illustrate the effectiveness of this method.展开更多
This paper investigates the control and synchronization of hyperchaotic Chen system based on the passive theory. By using two outputs, novel passive controllers are respectively designed to realize the globally asympt...This paper investigates the control and synchronization of hyperchaotic Chen system based on the passive theory. By using two outputs, novel passive controllers are respectively designed to realize the globally asymptotical stability of the hyperchaotic Chen system and the error dynamical system, which avoids mistakes in Ref.[11], where function W（z） cannot guarantee that fo（z） is globally asymptotically stable via only one output and W（z） is the Lyapunov function of f0（z）. Furthermore, numerical simulations are given to show the effectiveness of our method.展开更多
This paper presents chaos synchronization between two different four-dimensional （4D） hyperchaotic Chen systems by nonlinear feedback control laws. A modified 4D hyperchaotic Chen system is obtained by changing the ...This paper presents chaos synchronization between two different four-dimensional （4D） hyperchaotic Chen systems by nonlinear feedback control laws. A modified 4D hyperchaotic Chen system is obtained by changing the nonlinear function of the 4D hyperchaotic Chen system, furthermore, an electronic circuit to realize two different 4D hyperchaotic Chen systems is designed. With nonlinear feedback control method, chaos synchronization between two different 4D hyperchaotic Chen systems is achieved. Based on the stability theory~ the functions of the nonlinear feedback control for synchronization of two different 4D hyperchaotic Chen systems is derived, the range of feedback gains is determined. Numerical simulations are shown to verify the theoretical results.展开更多
This paper considers the synchronization of solutions for lattices of the coupled non-autonomous Chen system. By using the Lyapunov function, we show that when the second coupled operator is negative definite self-adj...This paper considers the synchronization of solutions for lattices of the coupled non-autonomous Chen system. By using the Lyapunov function, we show that when the second coupled operator is negative definite self-adjoint and its coefficient is suitable large, the Chen coupled lattice system is bounded dissipative （In particular, the solutions for lattices of the coupled autonomous Chen system converge to zero as t→∞）. The synchronization between any two solutions of the coupled Chen system can be slaved only by coefficients in the x- or y-component for the suitably large second coupled coefficient. Finally, some numerical simulations are given.展开更多
Based on Lyapunov theory, the adaptive generalized synchronization between Chen system and a multi-scroll chaotic system is investigated. According to the form of target function a proper adaptive controller is design...Based on Lyapunov theory, the adaptive generalized synchronization between Chen system and a multi-scroll chaotic system is investigated. According to the form of target function a proper adaptive controller is designed, by which the controlled Chen system can be synchronized with a multi-scroll chaotic system including unknown parameters. The Lyapunov direct method is exploited to prove that the synchronization error and parameter identification error both converge to zero. Numerical simulation results verify the feasibility of the proposed method further.展开更多
The synchronization of hyperchaotic Chen systems is considered. An adaptive synchronization approach and a cascade adaptive synchronization approach are presented to synchronize a drive system and a response system. B...The synchronization of hyperchaotic Chen systems is considered. An adaptive synchronization approach and a cascade adaptive synchronization approach are presented to synchronize a drive system and a response system. By utilizing an adaptive controller based on the dynamic compensation mechanism, exact knowledge of the systems is not necessarily required, and the synchronous speed is controllable by tuning the controller parameters. Sufficient conditions for the asymptotic stability of the two synchronization schemes are derived. Numerical simulation results demonstrate that the adaptive synchronization scheme with four control inputs and the cascade adaptive synchronization scheme with only one control signal are effective and feasible in chaos synchronization of hyperchaotic systems.展开更多
Based on passive theory, this paper studies a hybrid chaotic dynamical system from the mathematics perspective to implement the control of system stabilization. According to the Jacobian matrix of the nonlinear system...Based on passive theory, this paper studies a hybrid chaotic dynamical system from the mathematics perspective to implement the control of system stabilization. According to the Jacobian matrix of the nonlinear system, the stabilization control region is gotten. The controller is designed to stabilize fast the minimum phase Lorenz-Chen chaotic system after equivalently transforming from chaotic system to passive system. The simulation results show that the system not only can be controlled at the different equilibria, but also can be transformed between the different chaotic attractors.展开更多
In this paper we present a new version of Chen＇s system： a piecewise linear （PWL） Chert system of fractional-order. Via a sigmoid-like function, the discontinuous system is transformed into a continuous system. By...In this paper we present a new version of Chen＇s system： a piecewise linear （PWL） Chert system of fractional-order. Via a sigmoid-like function, the discontinuous system is transformed into a continuous system. By numerical simulations, we reveal chaotic behaviors and also multistability, i.e., the existence of small pararheter windows where, for some fixed bifurcation parameter and depending on initial conditions, coexistence of stable attractors and chaotic attractors is possible. Moreover, we show that by using an algorithm to switch the bifurcation parameter, the stable attractors can be numerically approximated.展开更多
In this paper, a novel four dimensional hyper-chaotic system is coined based on the Chen system, which contains two quadratic terms and five system parameters. The proposed system can generate a hyper-chaotic attracto...In this paper, a novel four dimensional hyper-chaotic system is coined based on the Chen system, which contains two quadratic terms and five system parameters. The proposed system can generate a hyper-chaotic attractor in wide parameters regions. By using the center manifold theorem and the local bifurcation theory, a pitchfork bifurcation is demonstrated to arise at the zero equilibrium point. Numerical analysis demonstrates that the hyper-cha^tic system can generate complex dynamical behaviors, e.g., a direct transition from quasi-periodic behavior to hyper-chaotic behavior. Finally, an electronic circuit is designed to implement the hyper-chaotic system, the experimental results are consist with the numerical simulations, which verifies the existence of the hyper-chaotic attractor. Due to the complex dynamic behaviors, this new hyper-cha^tic system is useful in the secure communication.展开更多
In this paper, we characterize all exponential factors and Darbouxian first integrals of the Chen system. We use the weight homogeneous polynomials and the method of characteristic curves to solve the linear partial d...In this paper, we characterize all exponential factors and Darbouxian first integrals of the Chen system. We use the weight homogeneous polynomials and the method of characteristic curves to solve the linear partial differential equations.展开更多
A systematic design process of adaptive synchronizatjon and parameter identification of an uncertain Chen chaotrcsystem is provided.With thia new and effettive method,parameter identification and synchronization of th...A systematic design process of adaptive synchronizatjon and parameter identification of an uncertain Chen chaotrcsystem is provided.With thia new and effettive method,parameter identification and synchronization of the Chensystem,with all the system parameters unknown,can be achieved simultaneously.Theoretical proof and numericalsimulation demonstrate the effectiveness and feaaibility of the proposed method.展开更多
This paper deals with the problem of chaos control and synchronization of the Chen-Liao system. From rigorous mathematic justification, the chaotic trajectories of the Chen-Liao system are led to a type of points whos...This paper deals with the problem of chaos control and synchronization of the Chen-Liao system. From rigorous mathematic justification, the chaotic trajectories of the Chen-Liao system are led to a type of points whose fourdimensional coordinates have a particular functional relation among them. Meanwhile, a new synchronization manner, reduced-order generalized synchronization （RGS）, is proposed which has the characteristic of having a functional relation between the slave and the partial master systems. It is shown that this new synchronization phenomenon can be realized by a novel technique. Numerical simulations have verified the effectiveness of the proposed scheme.展开更多
Since the past two decades, the time delay feedback control method has attracted more and more attention in chaos control studies because of its simplicity and efficiency compared with other chaos control schemes. Rec...Since the past two decades, the time delay feedback control method has attracted more and more attention in chaos control studies because of its simplicity and efficiency compared with other chaos control schemes. Recently, it has been proposed to suppress low-dimensional chaos with the notch filter feedback control method, which can be implemented in a laser system. In this work, we have analytically determined the controllable conditions for notch filter feedback controlling of Chen chaotic system in terms of the Hopf bifurcation theory. The conditions for notch filter feedback controlled Chen chaoitc system having a stable limit cycle solution are given. Meanwhile, we also analysed the Hopf bifurcation direction, which is very important for parameter settings in notch filter feedback control applications. Finally, we apply the notch filter feedback control methods to the electronic circuit experiments and numerical simulations based on the theoretical analysis. The controlling results of notch filter feedback control method well prove the feasibility and reliability of the theoretical analysis.展开更多
This paper brings attention on the hybrid synchronization of the Chen hyper-chaotic system by using some simple controllers. We give the sufficient conditions for achieving the goal by using the Lyapunov stability the...This paper brings attention on the hybrid synchronization of the Chen hyper-chaotic system by using some simple controllers. We give the sufficient conditions for achieving the goal by using the Lyapunov stability theory, and we verify our conclusion by numerical simulations.展开更多
From May 20 to 24,2025,CIIS President Chen Bo led a delegation to visit India.During the visit,the delegation attended the 20th meeting of the Shanghai Cooperation Organization(SCO)Forum hosted by the Indian Council o...From May 20 to 24,2025,CIIS President Chen Bo led a delegation to visit India.During the visit,the delegation attended the 20th meeting of the Shanghai Cooperation Organization(SCO)Forum hosted by the Indian Council of World Affairs(ICWA)and had in-depth exchanges with all participants on topics such as security,sustainable development and cultural cooperation in the SCO region.The delegation also had meetings with the Vivekananda International Foundation(VIF)and the Institute of Chinese Studies(ICS)in India.展开更多
Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman...Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman of Shandong Huasheng Textile Group Co.,Ltd.and leader of Hong Kong Huasheng Group,has the boots-on-the-ground confidence when discussing technological breakthroughs.展开更多
Objective:EPF3 is a fibrinolysin monomer isolated and purified from Pheretima vulgaris Chen,an earthworm used in traditional Chinese medicine as Dilong for treating blood stasis syndrome.Its composition,anticoagulant ...Objective:EPF3 is a fibrinolysin monomer isolated and purified from Pheretima vulgaris Chen,an earthworm used in traditional Chinese medicine as Dilong for treating blood stasis syndrome.Its composition,anticoagulant and fibrinolytic activities,and relevant mechanisms have been confirmed through in vitro experiments.However,whether it has antithrombotic effects in vivo and can be absorbed by the gastrointestinal tract is unknown.This study evaluates the antithrombotic effect in zebrafish and investigates the gastrointestinal stability and intestinal absorption mechanism of this protein in vitro.Methods:The antithrombotic effect of EPF3 in vivo was verified using the zebrafish thrombus model induced by arachidonic acid and FeCl3.Then,the protein bands of EPF3 incubated with simulated gastric fluid(SGF),simulated intestinal fluid(SIF),and homogenate of Caco-2 cells(HC2C)were analyzed by sodium dodecyl sulfate–polyacrylamide gel electrophoresis to evaluate its gastrointestinal stability.Finally,the transport behavior and absorption mechanism of EPF3 were studied using Caco-2 cell monolayer.Results:EPF3 could significantly enhance the returned blood volume and blood flow velocity in zebrafish with platelet aggregation thrombus induced by arachidonic acid.It could also prolong the formation time of tail artery thrombus and increase the blood flow velocity in zebrafish with vessel injury thrombus induced by FeCl3.EPF3 was stable in SIF and HC2C and unstable in SGF.The permeability of EPF3 in Caco-2 monolayer was time-dependent and concentration-dependent.The efflux ratio was less than1.2 during transport,and the transport behavior was not affected by inhibitors.EPF3 could reversibly reduce the expression of tight junction-related proteins,including zonula occludens-1,occludin,and claudin-1 in Caco-2 cells.Conclusion:EPF3 could play a thrombolytic and antithrombotic role in zebrafish.It could be transported and absorbed into the intestine through cellular bypass pathway by opening the intestinal epithelium tight junction.This study provides a scientific explanation for the antithrombotic effect of earthworm and provides a basis for the feasibility of subsequent development of EPF3 as an antithrombotic enteric-soluble preparation.Please cite this article as:Zhong WL,Yang JQ,Liu H,Wu YL,Shen HJ,Li PY,Du SY.Antithrombotic effect in zebrafish of a fibrinolytic protein EPF3 from Dilong(Pheretima vulgaris Chen)and its transport mechanism in Caco-2 monolayer through cell bypass pathway.J Integr Med.2025;23(4):415–428.展开更多
文摘Based on the Chen chaotic system, a new four-dimensional hyperchaotic Chen system is constructed, and the basic dynamic behaviours of the system were studied, and the generalized synchronization has been observed in the coupled four-dimensional hyperchaotic Chen system with unknown parameters. The Routh Hurwitz theorem is used to derive the conditions of stability of this system. Furthermore based on Lyapunov stability theory, the control laws and adaptive laws of parameters are obtained to make generalized synchronization of the coupled new four-dimensional hyperchaotic Chen systems. Numerical simulation results are presented to illustrate the effectiveness of this method.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 60574045 and 70771084)
文摘This paper investigates the control and synchronization of hyperchaotic Chen system based on the passive theory. By using two outputs, novel passive controllers are respectively designed to realize the globally asymptotical stability of the hyperchaotic Chen system and the error dynamical system, which avoids mistakes in Ref.[11], where function W（z） cannot guarantee that fo（z） is globally asymptotically stable via only one output and W（z） is the Lyapunov function of f0（z）. Furthermore, numerical simulations are given to show the effectiveness of our method.
基金Project supported by the National Natural Science Foundation of China （Grant No 90405011）, the Natural Science Foundation of Jiangsu Province, China （Grant No 05KJD120083） and the Natural Science Foundation of Nanjing Institute of Technology, China （Grant No KXJ06047）.
文摘This paper presents chaos synchronization between two different four-dimensional （4D） hyperchaotic Chen systems by nonlinear feedback control laws. A modified 4D hyperchaotic Chen system is obtained by changing the nonlinear function of the 4D hyperchaotic Chen system, furthermore, an electronic circuit to realize two different 4D hyperchaotic Chen systems is designed. With nonlinear feedback control method, chaos synchronization between two different 4D hyperchaotic Chen systems is achieved. Based on the stability theory~ the functions of the nonlinear feedback control for synchronization of two different 4D hyperchaotic Chen systems is derived, the range of feedback gains is determined. Numerical simulations are shown to verify the theoretical results.
基金supported by the National Natural Science Foundation of China (Grant No.10771139)
文摘This paper considers the synchronization of solutions for lattices of the coupled non-autonomous Chen system. By using the Lyapunov function, we show that when the second coupled operator is negative definite self-adjoint and its coefficient is suitable large, the Chen coupled lattice system is bounded dissipative （In particular, the solutions for lattices of the coupled autonomous Chen system converge to zero as t→∞）. The synchronization between any two solutions of the coupled Chen system can be slaved only by coefficients in the x- or y-component for the suitably large second coupled coefficient. Finally, some numerical simulations are given.
基金Project supported by the National Natural Science Foundation of China (Grant No. 50875259)
文摘Based on Lyapunov theory, the adaptive generalized synchronization between Chen system and a multi-scroll chaotic system is investigated. According to the form of target function a proper adaptive controller is designed, by which the controlled Chen system can be synchronized with a multi-scroll chaotic system including unknown parameters. The Lyapunov direct method is exploited to prove that the synchronization error and parameter identification error both converge to zero. Numerical simulation results verify the feasibility of the proposed method further.
基金Project supported by the National Basic Research Program of China (Grant No. 2007CB210106)
文摘The synchronization of hyperchaotic Chen systems is considered. An adaptive synchronization approach and a cascade adaptive synchronization approach are presented to synchronize a drive system and a response system. By utilizing an adaptive controller based on the dynamic compensation mechanism, exact knowledge of the systems is not necessarily required, and the synchronous speed is controllable by tuning the controller parameters. Sufficient conditions for the asymptotic stability of the two synchronization schemes are derived. Numerical simulation results demonstrate that the adaptive synchronization scheme with four control inputs and the cascade adaptive synchronization scheme with only one control signal are effective and feasible in chaos synchronization of hyperchaotic systems.
基金Project supported by the National Natural Science Foundation of China(Grant No60702023)Natural Science Foundation of Zhejiang Province,China(Grant No Y104414)
文摘Based on passive theory, this paper studies a hybrid chaotic dynamical system from the mathematics perspective to implement the control of system stabilization. According to the Jacobian matrix of the nonlinear system, the stabilization control region is gotten. The controller is designed to stabilize fast the minimum phase Lorenz-Chen chaotic system after equivalently transforming from chaotic system to passive system. The simulation results show that the system not only can be controlled at the different equilibria, but also can be transformed between the different chaotic attractors.
基金funded by the European Regional Development Funding via RISC projectby CPER Region Haute Normandie France,the Australian Research Council via a Future Fellowship(FT110100896)Discovery Project(DP140100203)
文摘In this paper we present a new version of Chen＇s system： a piecewise linear （PWL） Chert system of fractional-order. Via a sigmoid-like function, the discontinuous system is transformed into a continuous system. By numerical simulations, we reveal chaotic behaviors and also multistability, i.e., the existence of small pararheter windows where, for some fixed bifurcation parameter and depending on initial conditions, coexistence of stable attractors and chaotic attractors is possible. Moreover, we show that by using an algorithm to switch the bifurcation parameter, the stable attractors can be numerically approximated.
基金Project supported by the Natural Science Foundation of China (Grant Nos.61174094, 50977063, and 60904063)the Foundation of the Application Base and Frontier Technology Research Project of Tianjin, China (Grant No.10JCZDJC23100)the Development of Science and Technology Foundation of the Higher Education Institutions of Tianjin, China (Grant No.20080826)
文摘In this paper, a novel four dimensional hyper-chaotic system is coined based on the Chen system, which contains two quadratic terms and five system parameters. The proposed system can generate a hyper-chaotic attractor in wide parameters regions. By using the center manifold theorem and the local bifurcation theory, a pitchfork bifurcation is demonstrated to arise at the zero equilibrium point. Numerical analysis demonstrates that the hyper-cha^tic system can generate complex dynamical behaviors, e.g., a direct transition from quasi-periodic behavior to hyper-chaotic behavior. Finally, an electronic circuit is designed to implement the hyper-chaotic system, the experimental results are consist with the numerical simulations, which verifies the existence of the hyper-chaotic attractor. Due to the complex dynamic behaviors, this new hyper-cha^tic system is useful in the secure communication.
基金The project is partially supported by the NNSF of China grant No.10231020.
文摘In this paper, we characterize all exponential factors and Darbouxian first integrals of the Chen system. We use the weight homogeneous polynomials and the method of characteristic curves to solve the linear partial differential equations.
基金the Natioral Natural Science Foundation of China(Grant No 19531070)
文摘A systematic design process of adaptive synchronizatjon and parameter identification of an uncertain Chen chaotrcsystem is provided.With thia new and effettive method,parameter identification and synchronization of the Chensystem,with all the system parameters unknown,can be achieved simultaneously.Theoretical proof and numericalsimulation demonstrate the effectiveness and feaaibility of the proposed method.
基金Project supported by the National Natural Science Foundation of China （Grant Nos 10472091 and 1033203）.
文摘This paper deals with the problem of chaos control and synchronization of the Chen-Liao system. From rigorous mathematic justification, the chaotic trajectories of the Chen-Liao system are led to a type of points whose fourdimensional coordinates have a particular functional relation among them. Meanwhile, a new synchronization manner, reduced-order generalized synchronization （RGS）, is proposed which has the characteristic of having a functional relation between the slave and the partial master systems. It is shown that this new synchronization phenomenon can be realized by a novel technique. Numerical simulations have verified the effectiveness of the proposed scheme.
基金supported by the National Natural Science Foundation of China (Grant Nos.70571053,10405018 and 10747147)
文摘Since the past two decades, the time delay feedback control method has attracted more and more attention in chaos control studies because of its simplicity and efficiency compared with other chaos control schemes. Recently, it has been proposed to suppress low-dimensional chaos with the notch filter feedback control method, which can be implemented in a laser system. In this work, we have analytically determined the controllable conditions for notch filter feedback controlling of Chen chaotic system in terms of the Hopf bifurcation theory. The conditions for notch filter feedback controlled Chen chaoitc system having a stable limit cycle solution are given. Meanwhile, we also analysed the Hopf bifurcation direction, which is very important for parameter settings in notch filter feedback control applications. Finally, we apply the notch filter feedback control methods to the electronic circuit experiments and numerical simulations based on the theoretical analysis. The controlling results of notch filter feedback control method well prove the feasibility and reliability of the theoretical analysis.
文摘This paper brings attention on the hybrid synchronization of the Chen hyper-chaotic system by using some simple controllers. We give the sufficient conditions for achieving the goal by using the Lyapunov stability theory, and we verify our conclusion by numerical simulations.
文摘From May 20 to 24,2025,CIIS President Chen Bo led a delegation to visit India.During the visit,the delegation attended the 20th meeting of the Shanghai Cooperation Organization(SCO)Forum hosted by the Indian Council of World Affairs(ICWA)and had in-depth exchanges with all participants on topics such as security,sustainable development and cultural cooperation in the SCO region.The delegation also had meetings with the Vivekananda International Foundation(VIF)and the Institute of Chinese Studies(ICS)in India.
文摘Within the Huasheng Textile Industrial Park in Wudi Economic Development Zone,Binzhou,Shandong,a impressive figure over 1.8 meters tall shuttles back and forth between home and production workshop.Chen Hailin,Chairman of Shandong Huasheng Textile Group Co.,Ltd.and leader of Hong Kong Huasheng Group,has the boots-on-the-ground confidence when discussing technological breakthroughs.
基金supported by grants from the Fundamental Research Funds for the Central Universities(No.2020-JYB-ZDGG-032)National Natural Science Foundation of China(No.82104352)。
文摘Objective:EPF3 is a fibrinolysin monomer isolated and purified from Pheretima vulgaris Chen,an earthworm used in traditional Chinese medicine as Dilong for treating blood stasis syndrome.Its composition,anticoagulant and fibrinolytic activities,and relevant mechanisms have been confirmed through in vitro experiments.However,whether it has antithrombotic effects in vivo and can be absorbed by the gastrointestinal tract is unknown.This study evaluates the antithrombotic effect in zebrafish and investigates the gastrointestinal stability and intestinal absorption mechanism of this protein in vitro.Methods:The antithrombotic effect of EPF3 in vivo was verified using the zebrafish thrombus model induced by arachidonic acid and FeCl3.Then,the protein bands of EPF3 incubated with simulated gastric fluid(SGF),simulated intestinal fluid(SIF),and homogenate of Caco-2 cells(HC2C)were analyzed by sodium dodecyl sulfate–polyacrylamide gel electrophoresis to evaluate its gastrointestinal stability.Finally,the transport behavior and absorption mechanism of EPF3 were studied using Caco-2 cell monolayer.Results:EPF3 could significantly enhance the returned blood volume and blood flow velocity in zebrafish with platelet aggregation thrombus induced by arachidonic acid.It could also prolong the formation time of tail artery thrombus and increase the blood flow velocity in zebrafish with vessel injury thrombus induced by FeCl3.EPF3 was stable in SIF and HC2C and unstable in SGF.The permeability of EPF3 in Caco-2 monolayer was time-dependent and concentration-dependent.The efflux ratio was less than1.2 during transport,and the transport behavior was not affected by inhibitors.EPF3 could reversibly reduce the expression of tight junction-related proteins,including zonula occludens-1,occludin,and claudin-1 in Caco-2 cells.Conclusion:EPF3 could play a thrombolytic and antithrombotic role in zebrafish.It could be transported and absorbed into the intestine through cellular bypass pathway by opening the intestinal epithelium tight junction.This study provides a scientific explanation for the antithrombotic effect of earthworm and provides a basis for the feasibility of subsequent development of EPF3 as an antithrombotic enteric-soluble preparation.Please cite this article as:Zhong WL,Yang JQ,Liu H,Wu YL,Shen HJ,Li PY,Du SY.Antithrombotic effect in zebrafish of a fibrinolytic protein EPF3 from Dilong(Pheretima vulgaris Chen)and its transport mechanism in Caco-2 monolayer through cell bypass pathway.J Integr Med.2025;23(4):415–428.
