Background:The high coverage of annual routine health check-up in China is a unique phenomenon throughout the world.However,its clinical value is controversial.In this cohort study,we chose pancreatic cancer as a dise...Background:The high coverage of annual routine health check-up in China is a unique phenomenon throughout the world.However,its clinical value is controversial.In this cohort study,we chose pancreatic cancer as a disease model to explore the role of routine check-up in the prognosis of patients with pancreatic cancer.Methods:Data from 157 patients who were diagnosed with pancreatic cancer between January 2010 and April 2014 were collected.Patients were divided into two groups depending on how their disease was detected.Group A(n=85):Patients were diagnosed with pancreatic cancer in clinic visits.Group B(n=72):Patients were diagnosed with pancreatic cancer in routine check-ups.We compared their prognosis.Results:The tumor stage in group B was earlier than that in group A.The 1-year survival rate in group B was significantly higher than that in group A(74.6%vs.42.4%,P<0.001),while the 3-and 5-year survival rates of the two groups showed no significant difference(P>0.05).The difference of overall survival time between the two groups was not significant(22.0 vs.9.0 months,P=0.078).Conclusions:The stage of pancreatic cancer diagnosed in routine check-ups was earlier and therefore,the intervention was earlier which improved short-term survival rate.However,early intervention did not improve overall survival in the long-term.展开更多
Objective: In Japan, there are unique facilities (namely Ningen Dock) of health check-up, where asymptomatic participants undergo a medical examination at their own expense. The earlier occurrence of cervical cancer a...Objective: In Japan, there are unique facilities (namely Ningen Dock) of health check-up, where asymptomatic participants undergo a medical examination at their own expense. The earlier occurrence of cervical cancer and the concern on screening prompted us compare to the age distribution in the self-covered system with that of free physical check-up programs at public expense. Methods: We analyzed medical records of Japanese women, who underwent gynecological examinations at self-covered expense and at public expense between for the periods 2002-2011 and 2005-2009, respectively, restricting examinee’s age group. Results: For self-covered system, approximately 80% of the overall examinee population was occupied with three age groups 30-39, 40-49 and 50-59. The participants was extremely fewer in the over 60 years age group accounting for 10%, compared to those for the public expense-covered system, the over 60 years age group being 25%. Participant under the age of 30 years seemed to increase in chronological order in both systems. Conclusion: The level of knowledge on sexually transmitted infections may contribute to screening promotion for the younger women, while the elderly over 60 years’ attitudes toward screening may be mainly related to social-economic status and/or public expense support.展开更多
The present study aims to determine the gynecologic health status of asymptomatic women at a unique Japanese Health Check-up Institute, Ningen Dock. Medical records of Japanese women, who underwent gynecological medic...The present study aims to determine the gynecologic health status of asymptomatic women at a unique Japanese Health Check-up Institute, Ningen Dock. Medical records of Japanese women, who underwent gynecological medical (health) examinations between January 2011 and December 2016, were retrospectively reviewed. Of the cervical smears from 8927 women aged 18 - 85 years, 50 (0.6%) were classified as dysplastic and malignant changes: 18 of low-grade squamous intraepithelial lesion, 10 high-grade squamous intraepithelial lesion, 21 atypical squamous cells of undetermined significance and 1 cervical squamous cell carcinoma. No case of cervical adenocarcinoma was found. Ultrasonographic examination detected uterus enlargements and ovary tumors in 2.0% and 0.9% of cases, respectively. Most of participants (95.6%) revealed no gynecologic abnormalities. The present study based on the records of Ningen Dock, where asymptomatic participants undergo a medical examination at their own expense, showed very low incidence of abnormal cytologic and/or ultrasonographic findings.展开更多
Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data stud...Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.展开更多
Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed...Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.展开更多
Objective:To investigate the application effects of intelligent guidance systems in optimizing health check-up process management.Methods:A total of 400 examinees who underwent physical examinations at the hospital’s...Objective:To investigate the application effects of intelligent guidance systems in optimizing health check-up process management.Methods:A total of 400 examinees who underwent physical examinations at the hospital’s Health Management Center from January to December 2024 were randomly divided into a control group(200 cases)and an observation group(200 cases).The control group used traditional manual guidance methods,while the observation group employed the intelligent guidance system.The study compared two groups in terms of completion time,waiting time for each procedure,check-up efficiency scores,examinee satisfaction,and report issuance time.Results:The overall examination time in the observation group(85.3±12.7 minutes)was significantly shorter than that in the control group(142.6±18.5 minutes)(P<0.01);average waiting time per procedure decreased by 62.4%;check-up efficiency scores(8.9±0.8 points)were significantly higher than those in the control group(5.2±1.1 points)(P<0.01);satisfaction reached 96.5%,significantly higher than the control group’s 78.0%(P<0.01);and report issuance time was advanced by 1.5 days.Conclusion:Intelligent guidance systems can significantly optimize check-up processes,improve work efficiency,and examinee satisfaction,demonstrating significant clinical application value.展开更多
Background: Systematic chest X-ray is the most prescribed examination by occupational physicians during periodic medical check-ups in our context, unlike in most countries where this practice has been discontinued. Ob...Background: Systematic chest X-ray is the most prescribed examination by occupational physicians during periodic medical check-ups in our context, unlike in most countries where this practice has been discontinued. Objective: The objective was to determine the diagnostic yield and cost-effectiveness of chest radiography during periodic medical check-ups of workers in Ngaoundere. Materials and Methods: A cross-sectional and descriptive study was carried out in Ngaoundere Regional Hospital from January to December 2018, concerning all persons coming to perform a systematic chest X-ray in the context of the periodic medical check-up having been consented to participate in the study. Posteroanterior (PA) chest radiographs were obtained from all workers during this periodic medical check-up. The variables studied were: age, sex, clinical manifestations, antecedents, job type, cost, and chest X-ray results. Statistical analysis was performed using the Sphinx Plus2-Lexica-V5 Edition software. Results: 753 workers were selected for this study, of whom 88.04% were men and 11.96% were women, a sex ratio H/F is of 7.4, the average age was 39 ± 7.89 years with extremes of 24 and 56 years, the most frequent job type was the administration (38.37%), the storekeepers (17.92) and the drivers (15.27%), most of them were asymptomatic (97.47%), some had cough (2.52%), chest pain (2.12%), dyspnea (0.26%) and fever (0.13%). History was dominated by lung infection (2.39%), pleurisy (1.06%) and tuberculosis (0.79%). 7.43% of workers occasionally smoked tobacco and consumed alcohol. 41 cases of pathologies (5.44%) were found on the chest X-ray, including 1 case (0.13%) of evolutionary pathology, 40 cases (5.31%) of sequelae pathologies. When the results of the chest X-ray are compared with the clinical signs and the pathological history of the workers, it is found that the only case with evolutionary abnormalities on the chest X-ray showed clinical signs and that the other cases with sequelae abnormalities had either clinical signs or antecedents related to these abnormalities. The cost of a chest X-ray at the time of our study was 5,000 FCFA ($8.59), for a total of 3,765,000 FCFA ($6473.74) for all the X-rays performed. Conclusion: In view of the low rate of abnormalities on the chest X-ray and the sequelae nature of the pathologies, it can be said that the routine X-ray of the chest during the periodic medical check-ups has a low diagnostic yield and a low cost-effectiveness ratio and is not profitable. It should be non-systematic and case-by-case based on the clinical context and background of workers.展开更多
Introduction: In Japan, there is free physical check-up programs of cancer screening, by which asymptomatic participants undergo a medical examination at public expense. The present study aims to describe their gyneco...Introduction: In Japan, there is free physical check-up programs of cancer screening, by which asymptomatic participants undergo a medical examination at public expense. The present study aims to describe their gynecologic findings and compare them with the literatures reported from general hospitals and self-paid check-up programs. Methods: Medical records of Japanese women, who underwent gynecological examinations at public expense between 2005 and 2009, were retrospectively reviewed. Results: Of the cervical smears from 2850 women aged 21 - 82 years, 33 (1.1%) were classified as dysplastic and malignant changes: 28 of low-grade squamous intraepithelial lesion (LSIL), 3 high-grade squamous intraepithelial lesion (HSIL), 2 atypical squamous cells of undeterimined significance (ASC-US). No case of cervical squamous cell carcinoma or adenocarcinoma was found. Ultrasonographic examination detected uterus enlargements and ovary tumors in less than 1% of cases. Most of participants (98%) revealed no gynecologic abnormalities. Conclusion: Annual gynecologic screening and proper follow-up programs even against asymptomatic women may remarkably reduce the probability of (pre)malignant disease.展开更多
Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of compara...Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of comparative studies on the current status of HP infection in high- and low-altitude. Therefore, this study aims to investigate the current status and differences in HP infection between the health check-up populations in the highland region and the plain area. Methods: This is a multicenter cross-sectional study, using convenience sampling method, which included the health check-up population of Ruoergai County People’s Hospital and the health check-up population of Deyang City People’s Hospital from January 2023 to December 2023, to carry out the questionnaire survey of HP-related factors, and to detect HP infection by a 13C-urea breath test. Results: The number of positives was 144 out of 260 health checkups in the plateau region, with a detection rate of 55.4%, which was significantly higher than that of 29.8% in the plains (P H. pylori infection-positive population, the health checkups in the plateau group had a lower education level, a higher proportion of overweight and obesity, a higher proportion of frequent smokers, a higher frequency of frequent eating out, and a lower proportion of abnormalities of uric acid, total cholesterol, LDL cholesterol, alanine aminotransferase, aspartate aminotransferase, and direct bilirubin but a higher proportion of abnormalities of total bilirubin. There was no statistically significant difference between the two groups in terms of age, gender, history of alcohol consumption, family history, urea, creatinine, and blood glucose. Conclusion: Preliminary results indicate that the rate of HP infection in the plateau population is significantly higher than that in the plains, and HP-related health education should be strengthened in the plateau region.展开更多
Background The assembled data from a population could provide information on health trends within the population.The aim of this research was to extract and know basic health information from an urban professional pop...Background The assembled data from a population could provide information on health trends within the population.The aim of this research was to extract and know basic health information from an urban professional population in Beijing.Methods Data analysis was carried out in a population who underwent a routine medical check-up and aged 〉20 years,including 30 058 individuals.General information,data from physical examinations and blood samples were collected in the same method.The health status was separated into three groups by the criteria generated in this study,i.e.,people with common chronic diseases,people in a sub-clinic situation,and healthy people.The proportion of both common diseases suffered and health risk distribution of different age groups were also analyzed.Results The proportion of people with common chronic diseases,in the sub-clinic group and in the healthy group was 28.6%,67.8% and 3.6% respectively.There were significant differences in the health situation in different age groups.Hypertension was on the top of list of self-reported diseases.The proportion of chronic diseases increased significantly in people after 35 years of age.Meanwhile,the proportion of sub-clinic conditions was decreasing at the same rate.The complex risk factors to health in this population were metabolic disturbances （61.3%）,risk for tumor （2.7%）,abnormal results of morphological examination （8.2%） and abnormal results of lab tests of serum （27.8%）.Conclusions Health information could be extracted from a complex data set from the heath check-ups of the general population.The information should be applied to support prevention and control chronic diseases as well as for directing intervention for patients with risk factors for disease.展开更多
Background and Objectives:We aimed to investigate the association of triglyceride–glucose(TyG)index with hypertension and compare the discriminative power of the TyG index,lipid,glycemic parameters for hypertension u...Background and Objectives:We aimed to investigate the association of triglyceride–glucose(TyG)index with hypertension and compare the discriminative power of the TyG index,lipid,glycemic parameters for hypertension using the China Health Examination Collaborative study(CHEC Study).Methods and Study Design:Data were collected at Ningbo Mingzhou Hospital and Beijing physical examination center from the CHEC Study during 2014 and 2021.Participants with≥2 medical check-up times were included.The TyG index is the logarithmized product of fasting triglyceride and glucose.Generalised estimation equation(GEE)model was used to evaluate the association between the TyG index,lipid parameters,glycemic parameters and hypertension.Receiver operating characteristic(ROC)analysis was performed to explore the predictive ability of TyG index on hypertension at different years of medical check-up.Results:112,902 participants with an average age of 42.8 years were recruited in the study,36,839 participants developed hypertension over the 8-year period.GEE model analysis showed that the ORs with 95%CI of hypertension were 3.35(3.15-3.57),1.86(1.76-1.95),1.67(1.58-1.78),1.45(1.33-1.58),1.24(1.19-1.29),0.92(0.86-0.99),and 1.90(1.83-1.97)in the highest versus lowest quintiles of TyG index,TG/HDL-C ratio,TG,TC,LDL-C,HDL-C and FPG in model 2.The area under the ROC curve of the overall years of medical check-up was significantly higher than a particular year in predicting hypertension(AUC:0.883,p<0.05).Conclusions:TyG index is associated with hypertension and shows the superior discriminative ability for hypertension compared with lipid and glycemic parameters.展开更多
基金the National Natural Science Foundation of China(81272075 and 81801572)the Medical and Health Science Foundation of Zhejiang Province(2019327552)+1 种基金the Foundation of Key Research Project of Zhejiang Province for Traditional Chinese Medicine(2019ZZ014)the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine(2017-XKA36).
文摘Background:The high coverage of annual routine health check-up in China is a unique phenomenon throughout the world.However,its clinical value is controversial.In this cohort study,we chose pancreatic cancer as a disease model to explore the role of routine check-up in the prognosis of patients with pancreatic cancer.Methods:Data from 157 patients who were diagnosed with pancreatic cancer between January 2010 and April 2014 were collected.Patients were divided into two groups depending on how their disease was detected.Group A(n=85):Patients were diagnosed with pancreatic cancer in clinic visits.Group B(n=72):Patients were diagnosed with pancreatic cancer in routine check-ups.We compared their prognosis.Results:The tumor stage in group B was earlier than that in group A.The 1-year survival rate in group B was significantly higher than that in group A(74.6%vs.42.4%,P<0.001),while the 3-and 5-year survival rates of the two groups showed no significant difference(P>0.05).The difference of overall survival time between the two groups was not significant(22.0 vs.9.0 months,P=0.078).Conclusions:The stage of pancreatic cancer diagnosed in routine check-ups was earlier and therefore,the intervention was earlier which improved short-term survival rate.However,early intervention did not improve overall survival in the long-term.
文摘Objective: In Japan, there are unique facilities (namely Ningen Dock) of health check-up, where asymptomatic participants undergo a medical examination at their own expense. The earlier occurrence of cervical cancer and the concern on screening prompted us compare to the age distribution in the self-covered system with that of free physical check-up programs at public expense. Methods: We analyzed medical records of Japanese women, who underwent gynecological examinations at self-covered expense and at public expense between for the periods 2002-2011 and 2005-2009, respectively, restricting examinee’s age group. Results: For self-covered system, approximately 80% of the overall examinee population was occupied with three age groups 30-39, 40-49 and 50-59. The participants was extremely fewer in the over 60 years age group accounting for 10%, compared to those for the public expense-covered system, the over 60 years age group being 25%. Participant under the age of 30 years seemed to increase in chronological order in both systems. Conclusion: The level of knowledge on sexually transmitted infections may contribute to screening promotion for the younger women, while the elderly over 60 years’ attitudes toward screening may be mainly related to social-economic status and/or public expense support.
文摘The present study aims to determine the gynecologic health status of asymptomatic women at a unique Japanese Health Check-up Institute, Ningen Dock. Medical records of Japanese women, who underwent gynecological medical (health) examinations between January 2011 and December 2016, were retrospectively reviewed. Of the cervical smears from 8927 women aged 18 - 85 years, 50 (0.6%) were classified as dysplastic and malignant changes: 18 of low-grade squamous intraepithelial lesion, 10 high-grade squamous intraepithelial lesion, 21 atypical squamous cells of undetermined significance and 1 cervical squamous cell carcinoma. No case of cervical adenocarcinoma was found. Ultrasonographic examination detected uterus enlargements and ovary tumors in 2.0% and 0.9% of cases, respectively. Most of participants (95.6%) revealed no gynecologic abnormalities. The present study based on the records of Ningen Dock, where asymptomatic participants undergo a medical examination at their own expense, showed very low incidence of abnormal cytologic and/or ultrasonographic findings.
文摘Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.
文摘Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.
文摘Objective:To investigate the application effects of intelligent guidance systems in optimizing health check-up process management.Methods:A total of 400 examinees who underwent physical examinations at the hospital’s Health Management Center from January to December 2024 were randomly divided into a control group(200 cases)and an observation group(200 cases).The control group used traditional manual guidance methods,while the observation group employed the intelligent guidance system.The study compared two groups in terms of completion time,waiting time for each procedure,check-up efficiency scores,examinee satisfaction,and report issuance time.Results:The overall examination time in the observation group(85.3±12.7 minutes)was significantly shorter than that in the control group(142.6±18.5 minutes)(P<0.01);average waiting time per procedure decreased by 62.4%;check-up efficiency scores(8.9±0.8 points)were significantly higher than those in the control group(5.2±1.1 points)(P<0.01);satisfaction reached 96.5%,significantly higher than the control group’s 78.0%(P<0.01);and report issuance time was advanced by 1.5 days.Conclusion:Intelligent guidance systems can significantly optimize check-up processes,improve work efficiency,and examinee satisfaction,demonstrating significant clinical application value.
文摘Background: Systematic chest X-ray is the most prescribed examination by occupational physicians during periodic medical check-ups in our context, unlike in most countries where this practice has been discontinued. Objective: The objective was to determine the diagnostic yield and cost-effectiveness of chest radiography during periodic medical check-ups of workers in Ngaoundere. Materials and Methods: A cross-sectional and descriptive study was carried out in Ngaoundere Regional Hospital from January to December 2018, concerning all persons coming to perform a systematic chest X-ray in the context of the periodic medical check-up having been consented to participate in the study. Posteroanterior (PA) chest radiographs were obtained from all workers during this periodic medical check-up. The variables studied were: age, sex, clinical manifestations, antecedents, job type, cost, and chest X-ray results. Statistical analysis was performed using the Sphinx Plus2-Lexica-V5 Edition software. Results: 753 workers were selected for this study, of whom 88.04% were men and 11.96% were women, a sex ratio H/F is of 7.4, the average age was 39 ± 7.89 years with extremes of 24 and 56 years, the most frequent job type was the administration (38.37%), the storekeepers (17.92) and the drivers (15.27%), most of them were asymptomatic (97.47%), some had cough (2.52%), chest pain (2.12%), dyspnea (0.26%) and fever (0.13%). History was dominated by lung infection (2.39%), pleurisy (1.06%) and tuberculosis (0.79%). 7.43% of workers occasionally smoked tobacco and consumed alcohol. 41 cases of pathologies (5.44%) were found on the chest X-ray, including 1 case (0.13%) of evolutionary pathology, 40 cases (5.31%) of sequelae pathologies. When the results of the chest X-ray are compared with the clinical signs and the pathological history of the workers, it is found that the only case with evolutionary abnormalities on the chest X-ray showed clinical signs and that the other cases with sequelae abnormalities had either clinical signs or antecedents related to these abnormalities. The cost of a chest X-ray at the time of our study was 5,000 FCFA ($8.59), for a total of 3,765,000 FCFA ($6473.74) for all the X-rays performed. Conclusion: In view of the low rate of abnormalities on the chest X-ray and the sequelae nature of the pathologies, it can be said that the routine X-ray of the chest during the periodic medical check-ups has a low diagnostic yield and a low cost-effectiveness ratio and is not profitable. It should be non-systematic and case-by-case based on the clinical context and background of workers.
文摘Introduction: In Japan, there is free physical check-up programs of cancer screening, by which asymptomatic participants undergo a medical examination at public expense. The present study aims to describe their gynecologic findings and compare them with the literatures reported from general hospitals and self-paid check-up programs. Methods: Medical records of Japanese women, who underwent gynecological examinations at public expense between 2005 and 2009, were retrospectively reviewed. Results: Of the cervical smears from 2850 women aged 21 - 82 years, 33 (1.1%) were classified as dysplastic and malignant changes: 28 of low-grade squamous intraepithelial lesion (LSIL), 3 high-grade squamous intraepithelial lesion (HSIL), 2 atypical squamous cells of undeterimined significance (ASC-US). No case of cervical squamous cell carcinoma or adenocarcinoma was found. Ultrasonographic examination detected uterus enlargements and ovary tumors in less than 1% of cases. Most of participants (98%) revealed no gynecologic abnormalities. Conclusion: Annual gynecologic screening and proper follow-up programs even against asymptomatic women may remarkably reduce the probability of (pre)malignant disease.
文摘Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of comparative studies on the current status of HP infection in high- and low-altitude. Therefore, this study aims to investigate the current status and differences in HP infection between the health check-up populations in the highland region and the plain area. Methods: This is a multicenter cross-sectional study, using convenience sampling method, which included the health check-up population of Ruoergai County People’s Hospital and the health check-up population of Deyang City People’s Hospital from January 2023 to December 2023, to carry out the questionnaire survey of HP-related factors, and to detect HP infection by a 13C-urea breath test. Results: The number of positives was 144 out of 260 health checkups in the plateau region, with a detection rate of 55.4%, which was significantly higher than that of 29.8% in the plains (P H. pylori infection-positive population, the health checkups in the plateau group had a lower education level, a higher proportion of overweight and obesity, a higher proportion of frequent smokers, a higher frequency of frequent eating out, and a lower proportion of abnormalities of uric acid, total cholesterol, LDL cholesterol, alanine aminotransferase, aspartate aminotransferase, and direct bilirubin but a higher proportion of abnormalities of total bilirubin. There was no statistically significant difference between the two groups in terms of age, gender, history of alcohol consumption, family history, urea, creatinine, and blood glucose. Conclusion: Preliminary results indicate that the rate of HP infection in the plateau population is significantly higher than that in the plains, and HP-related health education should be strengthened in the plateau region.
文摘Background The assembled data from a population could provide information on health trends within the population.The aim of this research was to extract and know basic health information from an urban professional population in Beijing.Methods Data analysis was carried out in a population who underwent a routine medical check-up and aged 〉20 years,including 30 058 individuals.General information,data from physical examinations and blood samples were collected in the same method.The health status was separated into three groups by the criteria generated in this study,i.e.,people with common chronic diseases,people in a sub-clinic situation,and healthy people.The proportion of both common diseases suffered and health risk distribution of different age groups were also analyzed.Results The proportion of people with common chronic diseases,in the sub-clinic group and in the healthy group was 28.6%,67.8% and 3.6% respectively.There were significant differences in the health situation in different age groups.Hypertension was on the top of list of self-reported diseases.The proportion of chronic diseases increased significantly in people after 35 years of age.Meanwhile,the proportion of sub-clinic conditions was decreasing at the same rate.The complex risk factors to health in this population were metabolic disturbances （61.3%）,risk for tumor （2.7%）,abnormal results of morphological examination （8.2%） and abnormal results of lab tests of serum （27.8%）.Conclusions Health information could be extracted from a complex data set from the heath check-ups of the general population.The information should be applied to support prevention and control chronic diseases as well as for directing intervention for patients with risk factors for disease.
文摘Background and Objectives:We aimed to investigate the association of triglyceride–glucose(TyG)index with hypertension and compare the discriminative power of the TyG index,lipid,glycemic parameters for hypertension using the China Health Examination Collaborative study(CHEC Study).Methods and Study Design:Data were collected at Ningbo Mingzhou Hospital and Beijing physical examination center from the CHEC Study during 2014 and 2021.Participants with≥2 medical check-up times were included.The TyG index is the logarithmized product of fasting triglyceride and glucose.Generalised estimation equation(GEE)model was used to evaluate the association between the TyG index,lipid parameters,glycemic parameters and hypertension.Receiver operating characteristic(ROC)analysis was performed to explore the predictive ability of TyG index on hypertension at different years of medical check-up.Results:112,902 participants with an average age of 42.8 years were recruited in the study,36,839 participants developed hypertension over the 8-year period.GEE model analysis showed that the ORs with 95%CI of hypertension were 3.35(3.15-3.57),1.86(1.76-1.95),1.67(1.58-1.78),1.45(1.33-1.58),1.24(1.19-1.29),0.92(0.86-0.99),and 1.90(1.83-1.97)in the highest versus lowest quintiles of TyG index,TG/HDL-C ratio,TG,TC,LDL-C,HDL-C and FPG in model 2.The area under the ROC curve of the overall years of medical check-up was significantly higher than a particular year in predicting hypertension(AUC:0.883,p<0.05).Conclusions:TyG index is associated with hypertension and shows the superior discriminative ability for hypertension compared with lipid and glycemic parameters.
